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| Product | Description | |
|---|---|---|
| RVD-Hpα | RVD-Hpα is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. CAS No. 1193362-76-3. Molecular formula: C65H105N19O17. Mole weight: 1424.66. |  |
| RVD-Hpα acetate | RVD-Hpα acetate is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+. It is also a high-affinity CB2 positive allosteric modulator (Ki = 50 nM). Alternative Names: H-Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH.CH3CO2H; L-arginyl-L-valyl-L-alpha-aspartyl-L-prolyl-L-valyl-L-asparagyl-L-phenylalanyl-L-lysyl-L-leucyl-L-leucyl-L-seryl-L-histidine. Grades: ≥95%. Molecular formula: C67H109N19O19. Mole weight: 1484.71. | |
| R-Venlafaxine | R-Venlafaxine. Group: Biochemicals. Alternative Names: 1-[ (1R) -2- (Dimethylamino) -1- (4-methoxyphenyl) ethyl]cyclohexanol; (+)-Venlafaxine. Grades: Highly Purified. CAS No. 93413-46-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H27NO2. US Biological Life Sciences. |  Worldwide |
| R-Venlafaxine-di-p-toluoyl-D-tartrate Salt | A metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant. Group: Biochemicals. Grades: Highly Purified. CAS No. 272788-00-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| RVG | RVG (RVG29) is a blood-brain barrier-permeable peptide derived from rabies virus glycoprotein, which binds to the α-7 subunit of neuronal nicotinic acetylcholine receptor (AchR). RVG efficiently delivers drugs to nerve cells and antigen-presenting cells in a targeted manner, and enhances the efficiency of antigen presentation and drug delivery[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RVG29; RDP; Rabies Virus Glycoprotein-29. CAS No. 115136-25-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5623. |  |
| RVG-9R | RVG-9R, a chimeric rabies virus glycoprotein fragment, binds and transduces siRNA in vitro into neuronal cells, resulting in highly efficient gene silencing. Repeated administration of RVG-9R-bound siRNA did not induce inflammatory cytokines or anti-peptide antibodies. Alternative Names: Rabies Virus Glycoprotein (194-221) Nonaarginine Chimer; H-Tyr-Thr-Ile-Trp-Met-Pro-Glu-Asn-Pro-Arg-Pro-Gly-Thr-Pro-Cys-Asp-Ile-Phe-Thr-Asn-Ser-Arg-Gly-Lys-Arg-Ala-Ser-Asn-Gly-Gly-Gly-Gly-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-OH. Grades: ≥95%. CAS No. 1678417-57-6. Molecular formula: C201H334N82O55S2. Mole weight: 4843.51. | |
| RVG-Cys | RVG-Cys (RVG29-Cys) is a peptide derived from rabies virus glycoprotein (RVG29) with Cys attached to facilitate subsequent conjugation. RVG-Cys enhances the specific targeted delivery of proteins in brain tissue and neurons[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RVG29-Cys; RDP-Cys; Rabies Virus Glycoprotein-29-Cys. CAS No. 1186105-01-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5623A. | |
| RVT-501 | RVT-501, also referred to E6005, is a selective phosphodiesterase 4 (PDE4) inhibitor (IC50 = 2.8 nM) with potential effect to treat atopic dermatitis. Alternative Names: E-6005; E6005; E6005; RVT-501; RVT501; RVT 501; lotamilast; methyl 4-[[3-[6,7-dimethoxy-2-(methylamino)quinazolin-4-yl]phenyl]carbamoyl]benzoate; E6005; methyl 4-(((3-(6,7-dimethoxy-2-(methylamino)quinazolin-4-yl)phenyl)amino)carbonyl)benzoate. CAS No. 947620-48-6. Molecular formula: C26H24N4O5. Mole weight: 472.49. | |
| RWJ 21757 | RWJ 21757. Group: Biochemicals. Grades: Purified. CAS No. 121288-39-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ 50271 | RWJ 50271 is an selective and orally active inhibitor of lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction with an IC50 of 5.0 μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated cell adhesion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 162112-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110086. | |
| RWJ 50271 | RWJ 50271. Group: Biochemicals. Grades: Purified. CAS No. 162112-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ 52353 | RWJ 52353. Group: Biochemicals. Grades: Purified. CAS No. 245744-10-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| RWJ 56110 | RWJ 56110. Group: Biochemicals. Grades: Purified. CAS No. 252889-88-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| RWJ-56110 dihydrochloride | RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 (HY-108566). RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387505-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108556A. | |
| RWJ 67657 | RWJ 67657 is an orally active inhibitor of the MAP kinases p38alpha and p38beta (IC50s = 1 and 11 uM, respectively, in vitro) that is inactive against p38gamma and p38delta, as well as several other kinases. It blocks the release of TNF-alpha and IL-1beta from peripheral blood mononuclear cells stimulated with LPS (IC50s = 3 and 11 nM, respectively) and inhibits TNF-alpha production in LPS-treated mice and rats. RWJ 67657 potently blocks the proliferation of CD4+ peripheral blood T cells induced by CD28 stimulation alone (IC50 = 0.5-4nM). It is commonly used to study the roles of p38alpha and p38beta in cellular and whole animal systems. Group: Biochemicals. Alternative Names: 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol; 4-(4-Fluorophenyl)-2-(4-hydroxy-1-butynyl)-1-(3-phenylpropyl)-5-(4-Pyridyl)imidazole; JNJ 3026582; RWJ 67657. Grades: Highly Purified. CAS No. 215303-72-3. Pack Sizes: 1mg, 5mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RWJ-67657 | RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor with IC50s of 1 and 11 μM, respectively. RWJ-67657 displays no activity at p38γ and p38δ, and exhibits cardio protective effect. Anti-inflammatory and anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ 3026582. CAS No. 215303-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15505. | |
| RX-3117 | RX-3117 (TV-1360) is a potent and orally active anticancer and antimetaboliteagent. RX-3117 inhibits DNA methyltransferase 1 (DNMT1). RX-3117 shows antiproliferative and anti-tumour activity. RX-3117 induces cell cycle arrest at S phase and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TV-1360; Fluorocyclopentenylcytosine. CAS No. 865838-26-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-15228. | |
| RX 821002 hydrochloride | RX 821002 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 109544-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RXFP3/4 agonist 2 | RXFP3/4 agonist 2 is a potent, nonpeptide dual RXFP3/4 agonist (EC50=3.1 and 2.7 nM). RXFP3/4 agonist 2 also potently promotes interactions between RXFP3 and β-arrestin-2 with EC50 values in the range of 10-22 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2752378-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145278. | |
| RXP03 | RXP03 is a MMPs inhibitor with the Ki of 20 nM, 2.5 nM, 10 nM, 5nM and 105 nM for MMP-2, MMP-8, MMP-9, MMP-11, MMP-14, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 284667-65-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162038. | |
| RXP470.1 | RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a Ki of 0.2 nM against human MMP-12. RXP470.1 is 2 to 4 orders of magnitude less potent against other MMPs. RXP470.1 significantly reduces atherosclerotic plaque cross-sectional area in mouse. RXP470.1 results in less complex plaques with increased smooth muscle cell:macrophage ratio, less macrophage apoptosis, increased cap thickness, smaller necrotic cores, and decreased incidence of calcification[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RXP-470. CAS No. 891198-31-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-135517. | |
| RY785 | RY785 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with an IC50 of 0.05 μM for KV2.2. RY785 has analgesic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1393748-80-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114608. | |
| RY796 | RY796 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with IC50s of 0.25 μM and 0.09 μM for KV2.1 and KV2.2. RY796 has analgesic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1393441-53-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120033. | |
| Ryanodine | Ryanodine. Group: Biochemicals. Grades: Purified. CAS No. 15662-33-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ryanodine | Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Uses: Scientific research. Category: Signaling pathways. CAS No. 15662-33-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103306. | |
| Ryuvidine | Ryuvidine. Group: Biochemicals. Grades: Purified. CAS No. 265312-55-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ryuvidine | Ryuvidine is a potent inhibitor of SET domain-containing protein 8(SETD8) with an IC50 of 0.5 μM and suppresses monomethylation of H4K20. Ryuvidine also inhibits CDK4 with an IC50 of 6.0 μM. Ryuvidine also inhibits KDM5A and blocks DNA synthesis. Ryuvidine has anticancer activity against tumors such as breast cancer. Ryuvidine improves arthritis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 265312-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100624. | |
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