A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti- CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody. CAS No. 1375830-34-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99272.
Ulodesine
Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BCX4208, BCX 4208, BCX-4208, Ulodesine, DADMe-immucillin H. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. Purity: >98%. IUPACName: 7-(((3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one. Canonical SMILES: O=C1C(NC=C2CN3C[C@H](O)[C@@H](CO)C3)=C2N=CN1. Product ID: ACM548486595. Alfa Chemistry ISO 9001:2015 Certified.
Ulp1 peptidase
The enzyme from Saccharomyces cerevisiae can also recognize small ubiquitin-like modifier 1 (SUMO-1) from human as a substrate in both SUMO-processing (α-linked peptide bonds) and SUMO-deconjugation (ε-linked peptide bonds) reactions. Ulp1 has several functions, including an essential role in chromosomal segregation and progression of the cell cycle through the G2/M phase of the cell cycle. Belongs in peptidase family C48. Group: Enzymes. Synonyms: Smt3-protein conjugate proteinase; Ubl-specific protease 1; Ulp1; Ulp1 endopeptidase; Ulp1 protease. Enzyme Commission Number: EC 3.4.22.68. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4244; Ulp1 peptidase; EC 3.4.22.68; Smt3-protein conjugate proteinase; Ubl-specific protease 1; Ulp1; Ulp1 endopeptidase; Ulp1 protease. Cat No: EXWM-4244.
Ulta Cool
Ultra Cool is a precision ceramic and optical grinding and machining coolant that is ideal for machining and/or grinding precision technical ceramic and quartz materials. This coolant contains high amounts of specialized lubrication components and is coupled with a corrosion prevention package that provides excellent protection to the machinery. Ultra Cool is a non-petroleum-based grinding fluid, able to be easily integrated into the existing plant waste stream. Uses: Precision optics, technical ceramics. Group: Precision machining. Manufacturing grinding and machining fluids for brittle composites. Glass Production & Processing. Categories: Precision ceramic grinding coolant, Optical machining coolant.
Ultra-Conductive Graphene Sheet, 0.001" Thick, 8" Wide, 8" Long
Ultra-Conductive Graphene Sheet, 0.001" Thick, 8" Wide, 8" Long. Uses: Designed for use in research and industrial production. Product ID: ACMA00064479. Alfa Chemistry ISO 9001:2015 Certified.
Ultra Dispersed Diamond - P-L
Ultra Dispersed Diamond - P-L. Group: Elements nanoparticles. >96%.
Ultra Dispersed Diamond Powder-DC
Ultra Dispersed Diamond Powder-DC. Group: Elements nanoparticles. >98.5%.
Ultra Dispersed Diamond Powder - P
Ultra Dispersed Diamond Powder - P. Group: Elements nanoparticles. 97%+.
Ultra Dispersed Diamond - WC-DC
Ultra Dispersed Diamond - WC-DC. Group: Elements nanoparticles. >98.5%.
Ultra Dispersed Diamond - WS
Ultra Dispersed Diamond - WS. Group: Elements nanoparticles. >98.5%.
UHMW-PE is a fine material with spherical particles for use in coatings, lubricants, and polyolefin and polyamide compounding. This material contributes to improved dispersion when mixed with other fillers, and adds improved lubrication, scratch and impact resistance to the final polymeric compound. Uses: Fiber, medical, building & construction, automotive. Group: other plastics.
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, Other
Ultrapure Single-walled carbon nanotubes
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherS
Ultrapure SWCNT
Ultrapure SWCNT. Group: Single wall cnt. CAS No. 308068-56-6. >99.99% (SWCNT).
Ultrapure SWCNTs aqueous dispersion
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid;
Ultrapure SWCNTs NMP dispersion
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; Wet
Ulviprubart (ABC-008) is a monoclonal antibody targeting the KLRG1 receptor that selectively depletes highly differentiated cytotoxic T cells. Ulviprubart can be used in the study of inclusion body myositis (IBM)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABC-008. CAS No. 2569434-60-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990026.
Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Hydroxycoumarin; Hydrangin; NSC 19790. CAS No. 93-35-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0573.
Umbelliferone 99+% (HPLC)
Umbelliferone 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 93-35-6. Pack Sizes: 100g, 250g, 25g, 1Kg. US Biological Life Sciences.
Umbelliprenin, a prenylated coumarin, is an antioxidant with anticancer, anti-inflammatory and immunomodulatory effects. Umbelliprenin inhibits lipoxygenase managing the inflammation pathways. In inflammatory macrophages, Umbelliprenin suppresses nitric oxide production as well as inducible nitric oxide synthase (NO synthase) [1]. Uses: Scientific research. Group: Natural products. CAS No. 23838-17-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-127029A.
Umbellulone
Offensive principle of the so-called "headache tree". Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitoningene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine. Group: Biochemicals. Grades: Highly Purified. CAS No. 546-78-1. Pack Sizes: 10mg. Molecular Formula: C10H14O. US Biological Life Sciences.
Worldwide
Umbilical Vein Endothelial Cells, Human (Frozen)
Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
Umbilical Vein Endothelial Cells, Human (T-25 flask)
Passage 1 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >20 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
Umbilicaric acid
Umbilicaric acid is an organic polyphenolic carboxylic acid. CAS No. 30666-92-3. Molecular formula: C25H22O10. Mole weight: 482.44.
Umbralisib
Umbralisib (TGR-1202) is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib can be used for haematological malignancies reseach [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TGR-1202; RP5264. CAS No. 1532533-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12279.
Umbralisib hydrochloride
Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TGR-1202 hydrochloride; RP5264 hydrochloride. CAS No. 1532533-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12279C.
Umeclidinium bromide
Umeclidinium bromide is a novel mAChR antagonist. The affinity ( K i ) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK573719A. CAS No. 869113-09-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12100.
Umeclidinium Bromide
Used in combination with vilanterol for long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist. It is a quaternary ammonium salt and an organic bromide salt. Alternative Names: Incruse Ellipta;GSK573719A;Umeclidinium (bromide). CAS No. 869113-09-7. Product ID: API869113097. Molecular formula: C29H34BrNO2. Mole weight: 508.5. EINECS: 638-761-1. SMILES: C1C[N+]2(CCC1(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCOCC5=CC=CC=C5.[Br-]. Category: Bronchiectasis APIs.
UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 ?M). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members. Uses: Scientific research. Group: Signaling pathways. CAS No. 518303-20-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18628.
Umibecestat free base
Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP-transgenic mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Umibecestat; CNP-520; CNP 520; CNP520. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1387560-01-1. Molecular formula: C19H15ClF7N5O2. Mole weight: 513.8. Purity: >98%. IUPACName: N-{6-[(3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-5-fluoropyridin-2-yl}-3-chloro-5- (trifluoromethyl)pyridine-2-carboxamide. Canonical SMILES: O=C(C1=NC=C(C(F)(F)F)C=C1Cl)NC2=NC([C@]3(C)CO[C@](C(F)(F)F)(C)C(N)=N3)=C(F)C=C2. Product ID: ACM1387560011. Alfa Chemistry ISO 9001:2015 Certified.
Umifenovir
Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells [1] [2]. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro [2]. Umifenovir shows anti-inflammatory activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 131707-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14904.
Umifenovir hydrochloride
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells [1] [2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 131707-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14904A.
Umirolimus
Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851536-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122402.
Umirolimus
A semi-synthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group. It is one of the most hydrophobic tacrolimus analogues. It binds to the cytosolic FK-binding protein 12 (FKBP12) to inhibit the mammalian target of rapamycin (mTOR) pathway. Synonyms: Biolimus; Biolimus A9; TRM 986; 42-O-(2-Ethoxyethyl)rapamycin. Grade: >95% by HPLC. CAS No. 851536-75-9. Molecular formula: C55H87NO14. Mole weight: 986.28.
UMK57
UMK57 is a small molecule compound that specifically promotes k-MT attachment error correction to inhibit chromosome missegregation, which can improve chromosome segregation fidelity by destabilizing kinetochore microtubule (k-MT) attachment during mitosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 342595-74-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122236.
UMP/CMP kinase
This eukaryotic enzyme is a bifunctional enzyme that catalyses the phosphorylation of both CMP and UMP with similar efficiency. dCMP can also act as acceptor. Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, CMP kinase and EC 2.7.4.22, UMP kinase. Group: Enzymes. Synonyms: cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMP kinase; deoxycytidine monophosphokinase; UMP-CMP kinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Enzyme Commission Number: EC 2.7.4.14. CAS No. 37278-21-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3195; UMP/CMP kinase; EC 2.7.4.14; 37278-21-0; cytidylate kinase; deoxycytidylate kinase; CTP:CMP phosphotransferase; dCMP kinase; deoxycytidine monophosphokinase; UMP-CMP kinase; ATP:UMP-CMP phosphotransferase; pyrimidine nucleoside monophosphate kinase; uridine monophosphate-cytidine monophosphate phosphotransferase. Cat No: EXWM-3195.