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This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. This enzyme participates in the biosynthesis of n-glycan and glycan structures. Group: Enzymes. Synonyms: UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase; UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase; UDP-. Enzyme Commission Number: EC 2.7.8.15. CAS No. 70431-08-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3315; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase; EC 2.7.8.15; 70431-08-2; UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase; UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase; UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase; uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase; chitobiosylpyrophosphoryldolichol synthase; dolichol phosphate N-acetylglucosamine-1-phosphotransferase; UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase; UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase. Cat No: EXWM-3315.
The enzyme, characterized from the methanogenic archaeon Methanococcus voltae, initiates N-linked glycosylation in that organism. The enzyme differs from the eukaryotic enzyme, which leaves one additional phosphate group on the dolichyl product (cf. EC 2.7.8.15, UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase). Group: Enzymes. Synonyms: aglK (gene name); dolichyl-phosphate α-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:dolichyl-phosphate α-N-acetyl-D-glucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.153. CAS No. 63363-73-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2379; UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminyltransferase; EC 2.4.1.153; 63363-73-5; aglK (gene name); dolichyl-phosphate α-N-acetylglucosaminyltransferase; UDP-N-acetyl-D-glucosamine:dolichyl-phosphate α-N-acetyl-D-glucosaminyltransferase. Cat No: EXWM-2379.
UDP-N-acetylglucosamine kinase
Toxic component of a toxin-antitoxin (TA) module. The phosphorylation of UDP-N-acetyl-D-glucosamine results in the inhibition of EC 2.5.1.7, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, the first committed step in cell wall synthesis, which is then blocked. The activity of this enzyme is inhibited when the enzyme binds to the cognate ε antitoxin. Group: Enzymes. Synonyms: UNAG kinase; ζ toxin; toxin PezT; ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase. Enzyme Commission Number: EC 2.7.1.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3007; UDP-N-acetylglucosamine kinase; EC 2.7.1.176; UNAG kinase; ζ toxin; toxin PezT; ATP:UDP-N-acetyl-D-glucosamine 3'-phosphotransferase. Cat No: EXWM-3007.
Some other glycoproteins with high-mannose can act as acceptors, but much more slowly than lysosomal enzymes. Group: Enzymes. Synonyms: N-acetyl glucosaminyl phosphotransferase; UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransfe. Enzyme Commission Number: EC 2.7.8.17. CAS No. 84012-69-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3316; UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase; EC 2.7.8.17; 84012-69-1; N-acetyl glucosaminyl phosphotransferase; UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase; UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase; uridine diphosphoacetylglucosamine-lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase; uridine diphosphoacetylglucosamine-glycoprotein acetylglucosamine-1-phosphotransferase; lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase; N-acetylglucosaminyl phosphotransferase; UDP-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase; UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase; UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase; UDP-N-acetylglucosamine:glycoprotein N-ace.
This enzyme catalyses the synthesis of N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components. The enzyme also initiates the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide in certain Escherichia coli strains, including K-12 and of teichoic acid in certain Gram-positive bacteria. Group: Enzymes. Synonyms: UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; WecA; WecA transferase; UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transfe. Enzyme Commission Number: EC 2.7.8.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3332; UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase; EC 2.7.8.33; UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; WecA; WecA transferase; UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase; GlcNAc-P-P-Und synthase; GPT (ambiguous); TagO; UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetylglucosaminephosphotransferase. Cat No: EXWM-3332.
UDP-N-acetyl-L-fucosamine synthase
Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis. Group: Enzymes. Synonyms: WbjD; Cap5G. Enzyme Commission Number: EC 5.1.3.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5414; UDP-N-acetyl-L-fucosamine synthase; EC 5.1.3.28; WbjD; Cap5G. Cat No: EXWM-5414.
UDP-N-acetylmuramate dehydrogenase
A flavoprotein (FAD). NADH can to a lesser extent replace NADPH. Group: Enzymes. Synonyms: MurB reductase; UDP-N-acetylenolpyruvoylglucosamine reductase; UDP-N-acetylglucosamine-enoylpyruvate reductase; UDP-GlcNAc-enoylpyruvate reductase; uridine diphosphoacetylpyruvoylglucosamine reductase; uridine diphospho-N-acetylglucosamine-enolpyruvate reductase; uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase. Enzyme Commission Number: EC 1.3.1.98. CAS No. 39307-28-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1368; UDP-N-acetylmuramate dehydrogenase; EC 1.3.1.98; 39307-28-3; MurB reductase; UDP-N-acetylenolpyruvoylglucosamine reductase; UDP-N-acetylglucosamine-enoylpyruvate reductase; UDP-GlcNAc-enoylpyruvate reductase; uridine diphosphoacetylpyruvoylglucosamine reductase; uridine diphospho-N-acetylglucosamine-enolpyruvate reductase; uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase. Cat No: EXWM-1368.
UDP-N-acetylmuramate-L-alanine ligase
Involved in the synthesis of a cell-wall peptide in bacteria. Group: Enzymes. Synonyms: MurC synthetase; UDP-N-acetylmuramoyl-L-alanine synthetase; uridine diphospho-N-acetylmuramoylalanine synthetase; UDP-N-acetylmuramoylalanine synthetase; L-alanine-adding enzyme; UDP-acetylmuramyl-L-alanine synthetase; UDPMurNAc-L-alanine synthetase; L-Ala ligase; uridine diphosphate N-acetylmuramate:L-alanine ligase; uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase; uridine-diphosphate-N-acetylmuramate. Enzyme Commission Number: EC 6.3.2.8. CAS No. 9023-52-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5771; UDP-N-acetylmuramate-L-alanine ligase; EC 6.3.2.8; 9023-52-3; MurC synthetase; UDP-N-acetylmuramoyl-L-alanine synthetase; uridine diphospho-N-acetylmuramoylalanine synthetase; UDP-N-acetylmuramoylalanine synthetase; L-alanine-adding enzyme; UDP-acetylmuramyl-L-alanine synthetase; UDPMurNAc-L-alanine synthetase; L-Ala ligase; uridine diphosphate N-acetylmuramate:L-alanine ligase; uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase; uridine-diphosphate-N-acetylmuramate:L-alanine ligase; UDP-MurNAc:L-alanine ligase; alanine-adding enzyme; UDP-N-acetylmuramyl:L-alanine ligase; UDP-N-acetylmuramate:L-alanine ligase (ADP-forming). Cat No: EXWM-5771.
The enzyme catalyses the reincorporation into peptidoglycan of the tripeptide L-alanyl-γ-D-glutamyl-2,6-meso-diaminoheptanedioate released during the maturation and constant remodeling of this bacterial cell wall polymer that occur during cell growth and division. The enzyme can also use the tetrapeptide L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine or the pentapeptide L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanyl-D-alanine in vivo and in vitro. Requires Mg2+.
The enzyme catalyses the reincorporation into peptidoglycan of the tripeptide L-alanyl-γ-D-glutamyl-2,6-meso-diaminoheptanedioate released during the maturation and constant remodeling of this bacterial cell wall polymer that occur during cell growth and division. The enzyme can also use the tetrapeptide L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine or the pentapeptide L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanyl-D-alanine in vivo and in vitro. Requires Mg2+. Group: Enzymes. Synonyms: murein peptide ligase; Mpl; yjfG (gene name); UDP-MurNAc:L-Ala-γ-D-Glu-meso-A2pm ligase; UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminopimelate ligase. Enzyme Commission Number: EC 6.3.2.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5763; UDP-N-acetylmuramate-L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptanedioate ligase; EC 6.3.2.45; murein peptide ligase; Mpl; yjfG (gene name); UDP-MurNAc:L-Ala-γ-D-Glu-meso-A2pm ligase; UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminopimelate ligase. Cat No: EXWM-5763.
UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase
Involved in the synthesis of a cell-wall peptide in bacteria. Group: Enzymes. Synonyms: MurD synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase; D-glutamate-adding enzyme; D-glutamate ligase; UDP-Mur-NAC-L-Ala:D-Glu ligase; UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming); UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (ADP-forming). Enzyme Commission Number: EC 6.3.2.9. CAS No. 9023-59-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5772; UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase; EC 6.3.2.9; 9023-59-0; MurD synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase; D-glutamate-adding enzyme; D-glutamate ligase; UDP-Mur-NAC-L-Ala:D-Glu ligase; UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming); UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (ADP-forming). Cat No: EXWM-5772.
Involved in the synthesis of a cell-wall peptide in bacteria. This enzyme adds diaminopimelate in Gram-negative organisms and in some Gram-positive organisms; in others EC 6.3.2.7 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase) adds lysine instead. It is the amino group of the L-centre of the diaminopimelate that is acylated. Group: Enzymes. Synonyms: MurE synthetase [ambiguous]; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; UDP-N-acetylmur. Enzyme Commission Number: EC 6.3.2.13. CAS No. 9075-9-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5734; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase; EC 6.3.2.13; 9075-09-6; MurE synthetase [ambiguous]; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming); UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminoheptanedioate γ-ligase (ADP-forming). Cat No: EXWM-5734.
Involved in the synthesis of cell-wall peptidoglycan. The D-lysine is attached to the peptide chain at the N6 position. The enzyme from Thermotoga maritima also performs the reaction of EC 6.3.2.7, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase. Group: Enzymes. Synonyms: UDP-MurNAc-L-Ala-D-Glu:D-Lys ligase; D-lysine-adding enzyme. Enzyme Commission Number: EC 6.3.2.37. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5754; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-D-lysine ligase; EC 6.3.2.37; UDP-MurNAc-L-Ala-D-Glu:D-Lys ligase; D-lysine-adding enzyme. Cat No: EXWM-5754.
Involved in the synthesis of a cell-wall peptide in bacteria. This enzyme adds lysine in some Gram-positive organisms; in others and in Gram-negative organisms EC 6.3.2.13 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase) adds 2,6-diaminopimelate instead. Group: Enzymes. Synonyms: MurE synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase; uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase; UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine γ-ligase (ADP-forming). Enzyme Commission Number: EC 6.3.2.7. CAS No. 9023-51-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5770; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase; EC 6.3.2.7; 9023-51-2; MurE synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase; uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase; UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine γ-ligase (ADP-forming). Cat No: EXWM-5770.
Involved with EC 6.3.2.4 (D-alanine-D-alanine ligase), EC 6.3.2.7 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase) or EC 6.3.2.13 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase), EC 6.3.2.8 (UDP-N-acetylmuramate-L-alanine ligase) and EC 6.3.2.9 (UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase) in the synthesis of a cell-wall peptide (click here) for diagram. This enzyme also catalyses the reaction when the C-terminal residue of the tripeptide is meso-2,4-diaminoheptanedioate (acylated at its L-centre), linking the D-Ala-D-Ala to the carboxy group of the L-centre. This activity was previously attributed to EC 6.3.2.15, which has since been deleted. Group: Enzymes. Synonyms: MurF s. Enzyme Commission Number: EC 6.3.2.10. CAS No. 55354-36-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5731; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase; EC 6.3.2.10; 55354-36-4; MurF synthetase; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase; UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase; uridine diphosphoacetylmuramoylpentapeptide synthetase; UDPacetylmuramoylpentapeptide synthetase; UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase. Cat No: EXWM-5731.
Requires Mg2+. Involved in biosynthesis of legionaminic acid, a nonulosonate derivative that is incorporated by some bacteria into assorted virulence-associated cell surface glycoconjugates. The initial product formed by the enzyme from Legionella pneumophila, which incorporates legionaminic acid into the O-antigen moiety of its lipopolysaccharide, is 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose, which rapidly mutarotates to a mixture of anomers. The enzyme from Campylobacter jejuni, which incorporates legionaminic acid into flagellin, prefers GDP-N,N'-diacetylbacillosamine. Group: Enzymes. Synonyms: UDP-Bac2Ac4Ac 2-epimerase; NeuC. Enzyme Commission Number: EC 3.2.1.184. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3868; UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing); EC 3.2.1.184; UDP-Bac2Ac4Ac 2-epimerase; NeuC. Cat No: EXWM-3868.
UDP-rhamnose
UDP-rhamnose, the activated form of Rhamnose (HY-N1420) in fungi, is a key precursor for fungi to synthesize rhamnose-containing glycans. UDP-rhamnose can be used in the research on the treatment of fungal diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1955-26-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10573.
UDP-sugar diphosphatase
A divalent cation is required for activity. UDP-sugar is the best substrate, although other nucleoside-sugar diphosphates are used as substrates with similar Km values but much lower maximum velocities. Thus, this enzyme has a specificity distinct from that of ADP-sugar diphosphatase (EC 3.6.1.21). Some but not all enzymes of this class also appear to have 5'-nucleotidase (see EC 3.1.3.5) activity. Group: Enzymes. Synonyms: nucleosidediphosphate-sugar pyrophosphatase; nucleosidediphosphate-sugar diphosphatase; UDP-sugar hydrolase; UDP-sugar pyrophosphatase. Enzyme Commission Number: EC 3.6.1.45. CAS No. 55354-38-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4622; UDP-sugar diphosphatase; EC 3.6.1.45; 55354-38-6; nucleosidediphosphate-sugar pyrophosphatase; nucleosidediphosphate-sugar diphosphatase; UDP-sugar hydrolase; UDP-sugar pyrophosphatase. Cat No: EXWM-4622.
UDP-Sugar pyrophosphorylase from Arabidopsis thaliana, Recombinant
In enzymology, an UTP-monosaccharide-1-phosphate uridylyltransferase (EC 2.7.7.64) is an enzyme that catalyzes the chemical reaction: UTP + a monosaccharide 1-phosphate ? diphosphate + UDP-monosaccharide. Thus, the two substrates of this enzyme are UTP and monosaccharide 1-phosphate, whereas its two products are diphosphate and UDP-monosaccharide. Group: Enzymes. Synonyms: UTP-monosaccharide-1-phosphate uridylyltransferase; EC 2.7.7.64; UDP-sugar pyrophosphorylase; USP. Enzyme Commission Number: EC 2.7.7.64. CAS No. 223918-15-8. Purity: min 95% by SDS-PAGE. UDP-Sugar pyrophosphorylase. Source: E. coli. Species: Arabidopsis thaliana. UTP-monosaccharide-1-phosphate uridylyltransferase; EC 2.7.7.64; UDP-sugar pyrophosphorylase; USP. Cat No: NATE-1503.
UDP-Sugar pyrophosphorylase from Bifidobacterium longum, Recombinant
In enzymology, an UTP-monosaccharide-1-phosphate uridylyltransferase (EC 2.7.7.64) is an enzyme that catalyzes the chemical reaction: UTP + a monosaccharide 1-phosphate ? diphosphate + UDP-monosaccharide. Thus, the two substrates of this enzyme are UTP and monosaccharide 1-phosphate, whereas its two products are diphosphate and UDP-monosaccharide. Group: Enzymes. Synonyms: UTP-monosaccharide-1-phosphate uridylyltransferase; EC 2.7.7.64; UDP-sugar pyrophosphorylase; USP. Enzyme Commission Number: EC 2.7.7.64. CAS No. 223918-15-8. Purity: min 95% by SDS-PAGE. UDP-Sugar pyrophosphorylase. Source: E. coli. Species: Bifidobacterium longum. UTP-monosaccharide-1-phosphate uridylyltransferase; EC 2.7.7.64; UDP-sugar pyrophosphorylase; USP. Cat No: NATE-1499.
UDP-sulfoquinovose synthase
Requires NAD+, which appears to oxidize UDP-α-D-glucose to UDP-4-dehydroglucose, which dehydrates to UDP-4-dehydro-6-deoxygluc-5-enose, to which sulfite is added. The reaction is completed when the substrate is rehydrogenated at C-4. The enzyme from Arabidopsis thaliana is specific for UDP-Glc and sulfite. Group: Enzymes. Synonyms: sulfite:UDP-glucose sulfotransferase; UDPsulfoquinovose synthase; UDP-6-sulfo-6-deoxyglucose sulfohydrolase. Enzyme Commission Number: EC 3.13.1.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3778; UDP-sulfoquinovose synthase; EC 3.13.1.1; sulfite:UDP-glucose sulfotransferase; UDPsulfoquinovose synthase; UDP-6-sulfo-6-deoxyglucose sulfohydrolase. Cat No: EXWM-3778.
UDP-xylose disodium
UDP-xylose disodium is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose disodium synthase (UXS). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose disodium participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 108320-89-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N11287A.
Ufenamate
Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for the treatment of skin diseases. Category: Active pharmaceutical ingredients. CAS No. 67330-25-0. Product ID: API67330250. Molecular formula: C18H18F3NO2. Mole weight: 337.34.
UFP-101
UFP-101. Group: Biochemicals. Grades: Purified. CAS No. 849024-68-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
UFP-101
UFP-101 is a potent, selective and competitive silent antagonist for the NOP opioid receptor, displaying > 3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 exhibits antinociceptive activity by opposing the action of nociceptin in vivo. Synonyms: UFP-101; UFP 101; UFP101. Grade: >98%. CAS No. 849024-68-6. Molecular formula: C82H138N32O21. Mole weight: 1908.19.
UFP 803
UFP 803. Group: Biochemicals. Grades: Purified. CAS No. 879497-82-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
UFP 803
UFP 803 is a urotensin-II (UT) receptor ligand that acts as a silent antagonist in most in vitro assays and in vivo. UFP 803 competitively antagonizes U-II induced contractions in the rat aorta (pIC50 = 7.46) and prevents plasma extravasation elicited by U-II in mice in vivo. Synonyms: UFP 803; UFP-803; UFP803. Grade: >98%. CAS No. 879497-82-2. Molecular formula: C50H64N10O12S2. Mole weight: 1061.24.
UGT8-IN-1
UGT8-IN-1 is a brain penetrable and orally active inhibitor of ceramide galactosyltransferase enzyme (UGT8). UGT8-IN-1 can be used in the study for lysosomal storage disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414349-93-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131703.
UH15-38
UH15-38 is a potent RIPK3 inhibitor with an IC50 value of 20 nM. UH15-38 blocks IAV (influenza A virus)-activated necroptosis. UH15-38 dampens IAV-induced lung injury[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2540881-21-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158312.
UHMW PE Tube, Rod and Sheet
UHMW PE Tube, Rod and Sheet.
UIO-66 (Ce)
Augment your research on Biodegradable Polymers with the reliable UIO-66 (Ce) from CD Bioparticles Drug Delivery. Group: Cerium-based mofs (ce-mof).
UIO-66-COOH
UIO-66-COOH, a dependable product from CD Bioparticles Drug Delivery, can help you with your research on Zirconium-based MOFs (Zr-MOF). Group: Zirconium-based mofs (zr-mof).
UIO-66-MSA
Take your Zirconium-based MOFs (Zr-MOF) research to the next level with the innovative UIO-66-MSA from CD Bioparticles Drug Delivery. Group: Zirconium-based mofs (zr-mof).
UIO-66-(OH)2
Ameliorate your research in MOFs Materials with UIO-66-(OH)2, a high-quality Zirconium-based MOFs (Zr-MOF) now available from CD Bioparticles Drug Delivery. Group: Zirconium-based mofs (zr-mof).
UIO-66-SO3H
Advance your Zn-MOFs research with UIO-66-SO3H, a high-quality MOFs available at CD Bioparticles that can help enhance your studies in drug delivery. Group: Zirconium-based mofs (zr-mof).
UiO-66 (Zr)
Explore the latest research on overview and characteristics of ophthalmic nano drug delivery system on CD Bioparticles' blog. Group: Zirconium-based mofs (zr-mof).
UIO-68 (Zr)
Boost your research in MOFs with UIO-68 (Zr)- a high quality Zr-MOF now available from CD Bioparticles, designed to facilitate your studies. Group: Zirconium-based mofs (zr-mof).
UK-1
UK-1, a benzoxazol derivative, has been found to be a Streptomyces metabolite that could exhibit anticancer activity and topoisomerase II restraination activity. Synonyms: UK 1, UK-1, UK1; [2,4'-Bibenzoxazole]-4-carboxylicacid, 2'-(2-hydroxyphenyl)-, methyl ester; ACMC-20n661; CTK4C6968; ZINC598610. Grade: 98%. CAS No. 151271-53-3. Molecular formula: C22H14N2O5. Mole weight: 386.36.
UK-101
UK-101 is a potent and selective immunoproteasome β1i (LMP2) inhibitor with an IC50 value of 104 nM, displays 144- and 10-fold selectivity over β1c (IC50=15 μM) and β5 subunit (IC50=1 μM), respectivey[1]. UK-101 induces cell apoptosis and can be used for the study of prostate cancer[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1000313-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119037.
UK122 TFA
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 940290-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111056.
UK 14,304
UK 14,304. Group: Biochemicals. Grades: Purified. CAS No. 59803-98-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UK 14,304 tartrate
UK 14,304 tartrate. Group: Biochemicals. Grades: Purified. CAS No. 70359-46-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
UK-1 (Antibiotic)
Antibiotic UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. It exhibits good antitumor activity but is devoid of antimicrobial activity. Antibiotic UK-1 acts as a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II. Group: Biochemicals. Grades: Highly Purified. CAS No. 151271-53-3. Pack Sizes: 1mg. US Biological Life Sciences.
Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 151271-53-3. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
Worldwide
UK-2A
UK-2A is produced by Streptomyces sp. 517-02. Its antifungal effect is similar to that of Antimycin A3. Molecular formula: C26H30N2O9. Mole weight: 514.52.
UK-2B
UK-2B is produced by Streptomyces sp. 517-02. Its antifungal effect is similar to that of Antimycin A3. Molecular formula: C27H30N2O9. Mole weight: 526.53.
UK-2C
UK-2C is produced by Streptomyces sp. 517-02. Its antifungal effect is similar to that of Antimycin A3. Molecular formula: C27H32N2O9. Mole weight: 528.55.
UK-2D
UK-2D is produced by Streptomyces sp. 517-02. Its antifungal effect is similar to that of Antimycin A3. Molecular formula: C27H32N2O9. Mole weight: 528.55.
UK 356618
UK 356618 (Compound 4j) is a potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) with an IC50 of 5.9 nM. UK 356618 is less potent against MMP-1, MMP-2, MMP-9, MMP-13 and MMP-14 compared with MMP-3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 230961-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107394.
UK-356618
Potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) (IC50 = 5.9 nM). Displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively). Group: Biochemicals. Alternative Names: (2R) -N1- [ (1S) -2, 2-Dimethyl-1- [ [ [ (1R) -1-phenylethyl] amino] carbonyl] propyl] -N4-hydroxy-2- [3- (2-methyl [1, 1'-biphenyl] -4-yl) propyl] butanediamide; UK 356618;PF-03890101. Grades: Highly Purified. CAS No. 230961-08-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
UK 370106
UK 370106. Group: Biochemicals. Grades: Purified. CAS No. 230961-21-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
UK-370106
UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. UK-370106 potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 230961-21-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107639.
UK-371804
UK-371804 is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 256477-09-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101214.
UK-383367
UK-383367 is an orally available pro-collagen C-protease inhibitor (BMP-1) with an IC50 value of 44 nM. UK-383367 can reduce renal fibrosis and inflammation in chronic kidney disease (CKD) and may be used to study postoperative skin scarring[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 348622-88-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13102.
UK-383367
UK-383367. Group: Biochemicals. Alternative Names: ( βR)-3-(Aminocarbonyl)- β-(3-cyclohexylpropyl)-N-hydroxy-1,2,4-oxadiazole-5-propanamide; 5-[(1R)-4-Cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl]-1,2,4-oxadiazole-3-carboxamide; UK 383367; PF-04171426. Grades: Highly Purified. CAS No. 348622-88-8. Pack Sizes: 10mg. Molecular Formula: C15H24N4O4, Molecular Weight: 324.38. US Biological Life Sciences.
Worldwide
UK-3A
UK-3A is an antifungal antibiotic obtained from the mycelial cake of Streptomyces sp. 517-02. The antifungal spectrum of UK-3A was relatively broad (MICs for yeasts and filamentous fungi: 1.56-6.25 and 0.39-1.56 micrograms/ml, respectively). The cytotoxic activity of UK-3A was weak (IC50: 18-100 micrograms/ml). Synonyms: UK3A; UK 3A. Molecular formula: C25H28N2O8. Mole weight: 484.5.
UK-41637
UK-41637 is a polyether antibiotic produced by Actinomadura cremea. It exhibits activity against gram-positive bacteria and parasites. Molecular formula: C46H77O15Na. Mole weight: 893.08.
UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380221-63-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107046.
UK4b
UK4b is a highly selective microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. UK4b possesses anti-inflammatory and analgesic effects. UK4b can block the growth of abdominal aortic aneurysms in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2171000-87-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162387.
UK-5099
Inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC). Group: Biochemicals. Alternative Names: 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic Acid; UK 5099; PF-06340678. Grades: Highly Purified. CAS No. 56396-35-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
UK-5099
UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-1005023. CAS No. 56396-35-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15475.
UK-5099 (PF-1005023)
UK5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier, inhibiting pyruvate transport across the plasma membrane of trypanosomes with Ki value of 49 μM. Group: Inhibitors. Alternative Names: PF-1005023. CAS No. 56396-35-1. Pack Sizes: 10mg. Product ID: S5317. Formula: C18H12N2O2. Smiles: C1=CC=C(C=C1)N2C=C(C3=CC=CC=C32)C=C(C#N)C(=O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
UK-61732
UK-61732 is a lactone antibiotic produced by Sacchraropolyspora hirsute 367. It inhibits gram-positive bacteria. Molecular formula: C28H37NO7. Mole weight: 499.59.
UK-63052
UK-63052 is one antibiotic of UK-63052 complex, which is produced by Streptomyces braegensis subsp. Japonicus. It is effective against some gram-positive bacteria including Staphylococcus aureus. Synonyms: Antibiotic UK-63052. CAS No. 120763-23-7. Molecular formula: C56H68N10O14. Mole weight: 1169.3.
UK-63598
UK-63598 is one antibiotic of UK-63052 complex, which is produced by Streptomyces braegensis subsp. Japonicus. It is effective against some gram-positive bacteria including Staphylococcus aureus. Synonyms: Antibiotic UK-63598; SW-163D. CAS No. 120796-23-8. Molecular formula: C53H62N10O14. Mole weight: 1127.3.
UK-65662
UK-65662 is one antibiotic of UK-63052 complex, which is produced by Streptomyces braegensis subsp. Japonicus. It is effective against some gram-positive bacteria including Staphylococcus aureus. Synonyms: Antibiotic UK-65662. CAS No. 120832-02-2. Molecular formula: C55H66N10O14. Mole weight: 1155.3.
UK-69735
UK-69735 is an antibiotic isolated from Amycolatopsis orientalis with activity against anaerobic bacteria, including clostridium difficile and Treponema hyodysenteriae (MIC = 0.39 and 0.78 μg/mL, respectively). Synonyms: Antibiotic UK-69735. Molecular formula: C58H86N2O18. Mole weight: 1099.3.
UK 78282 hydrochloride
UK 78282 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 136647-02-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.