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| Product | Description | |
|---|---|---|
| Icotinib Impurity 3 | Icotinib Impurity 3. Uses: For analytical and research use. CAS No. 1643673-51-1. Molecular formula: C22H20FN3O4. Mole weight: 409.42. Catalog: APB1643673511. |  |
| Icotinib Impurity 4 | Icotinib Impurity 4. Uses: For analytical and research use. CAS No. 1058651-82-3. Molecular formula: C28H29N3O11. Mole weight: 583.55. Catalog: APB1058651823. | |
| Icotinib Impurity 5 | Icotinib Impurity 5. Uses: For analytical and research use. CAS No. 2249867-59-0. Molecular formula: C18H13N3O2. Mole weight: 303.32. Catalog: APB2249867590. | |
| Icotinib Impurity 6 | Icotinib Impurity 6. Uses: For analytical and research use. CAS No. 1869913-77-8. Molecular formula: C20H21N3O5. Mole weight: 383.4. Catalog: APB1869913778. | |
| Icotinib Impurity 7 | Icotinib Impurity 7. Uses: For analytical and research use. CAS No. 2249867-60-3. Molecular formula: C19H15N3O2. Mole weight: 317.35. Catalog: APB2249867603. | |
| Icotinib Impurity 8 | Icotinib Impurity 8. Uses: For analytical and research use. CAS No. 153437-34-4. Molecular formula: C17H15N3O2. Mole weight: 293.33. Catalog: APB153437344. | |
| Icotinib Impurity 9 | Icotinib Impurity 9. Uses: For analytical and research use. CAS No. 412930-46-2. Molecular formula: C18H17N3O2. Mole weight: 307.35. Catalog: APB412930462. | |
| Icotrokinra | Icotrokinra (JNJ-77242113) is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-γ production in NK cells with an IC50 of 18.4 pM. Icotrokinra exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra can be used in the study of psoriasis, psoriatic arthritis, and inflammatory bowel disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-77242113; JNJ-2113; PN-235. CAS No. 2763602-16-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10587. |  |
| Icovamenib | Icovamenib (BMF-219) is a selective, orally active, irreversible Menin inhibitor. Icovamenib forms a stable and irreversible covalent bond with Menin. Icovamenib promotes selective and controlled proliferation of beta cells and improvement of beta cell function in ex vivo human islet cultures. Icovamenib enhances glycemic control in animal diabetic models. Icovamenib induces a dose-dependent enhancement in insulin secretion potentiated by the GLP-1 RA. Icovamenib can be used for the study of multiple hematologic malignancies, solid tumors, and diabetes mellitus, such as diffuse large B-cell lymphoma (DLBCL), multiple myeloma (MM) and chronic lymphocytic leukemia and type 2 diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMF-219; Menin-MLL inhibitor 21. CAS No. 2448172-22-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150105. | |
| ICRF-193 | ICRF-193 is a DNA Topoisomerase II inhibitor. (S,S)- and (R,R)-isomers ICRF-193 make up an racemic mixture, ICRF-196 (HY-118590A). ICRF-193 can inhibit DNA syntheses and induces apoptosis. ICRF-193 exhibits anti-cancer and anti-inflammation effects. ICRF-193 shows cardioprotective effect against anthracycline toxicity to cardiomyocytes. ICRF-193 can be used for the researches of cancer, infection, inflammation and cardiovascular disease, such as acute promyelocytic leukemia[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 21416-88-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118590. | |
| icrocaptide | icrocaptide. Synonyms: Icrocaptide. CAS No. 169543-49-1. Molecular formula: C21H40N8O5. |  |
| iCRT 14 | iCRT 14. Group: Biochemicals. Grades: Purified. CAS No. 677331-12-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Synonyms: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. Grade: >98%. CAS No. 677331-12-3. Molecular formula: C21H17N3O2S. Mole weight: 375.44. | |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase. Uses: Scientific research. Category: Signaling pathways. CAS No. 677331-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16665. | |
| iCRT3 | iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription. Uses: Scientific research. Category: Signaling pathways. CAS No. 901751-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103705. | |
| iCRT5 | iCRT5 is a Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor (IC50 value of 18 nM for Wnt responsive STF16 luciferase). iCRT5 disrupts the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin. Synonyms: iCRT5; iCRT-5; iCRT 5; 4-[5-(3,4-Dimethoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-butyric acid; 4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid; EN300-00774; AC1Q49FJ. Grade: 99%. CAS No. 18623-44-4. Molecular formula: C16H17NO5S2. Mole weight: 367.44. | |
| Icrucumab | Icrucumab is a human monoclonal antibody directed against vascular endothelial growth factor receptor-1 (VEGFR-1). Icrucumab inhibits ligand-dependent phosphorylation of VEGFR-1 and downstream signaling, making icrucumab an attractive candidate for antitumor activity. Synonyms: IMC-18F1. Grade: 95%. CAS No. 1024603-92-6. Molecular formula: C6514H10024N1756O2032S42. Mole weight: 146.8 kDa. | |
| Icrucumab | Icrucumab (Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1) is an IgG1 antibody inhibitor targeting VEGFR-1/FLT1 with anti-tumor activity. By blocking ligand-dependent phosphorylation and downstream signal transduction, Icrucumab reduces the activities of MAPK and Akt in breast cancer xenograft models, inhibits the proliferation and invasion of VEGFR-1-positive tumor cells, and reverses the conversion of M1 macrophages to the pro-tumor M2-like phenotype. Icrucumab also inhibits tumor cell proliferation, promotes apoptosis, and effectively suppresses tumor growth through direct targeting of tumors and host support mechanisms. In addition, Icrucumab exhibits a synergistic effect when combined with chemotherapeutic agents, and it is used in research related to various cancers including advanced solid malignancies, thyroid cancer, melanoma, and lung cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1. CAS No. 1024603-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99364. | |
| ID-11014A | ID-11014A is a potent and selective agonist of GPR40 (free fatty acid receptor 1) that can increase insulin secretion and reduce glucose levels. Studies shows that it has a lower liver toxicity than TAK-785 and an improved glucose tolerance. Uses: The potential treatment of diabetes. Synonyms: ID 11014A. | |
| ID-8 | ID-8. Group: Biochemicals. Alternative Names: ID 8, 1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol, AC1LGAMV, HY-15838. Grades: Highly Purified. CAS No. 147591-46-6. Pack Sizes: 25mg. Molecular Formula: C16 H14 N2O4, Molecular Weight: 298.3. US Biological Life Sciences. | Worldwide |
| ID-8 | ID-8 is a DYRK inhibitor, and sustains embryonic stem cell self-renewal in long-term culture. Synonyms: ID-8; ID 8; ID8. Grade: >98%. CAS No. 147591-46-6. Molecular formula: C16H14N2O4. Mole weight: 298.29. | |
| IDA, 1-20 cps | IDA, 1-20 cps. Mole weight: 212. |  |
| IDA, 2-8 cps | IDA, 2-8 cps. Mole weight: 212. | |
| Idactamab | Idactamab (INT-001) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5)[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: INT-001. CAS No. 2245205-37-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99654. | |
| Idarubicin | Idarubicin is an orally active and potent anthracycline antileukemic agent. Idarubicin inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin shows induction of DNA damage. Idarubicin inhibits DNA synthesis and of c-myc expression. Idarubicin inhibits the growth of bacteria and yeasts[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin. CAS No. 58957-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381A. | |
| Idarubicin | Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Synonyms: IMI30; IMI-30; IMI 30; NSC256439; NSC-256439; NSC 256439; 4-DMDR; IDA; 4-Demethoxydaunomycin; (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 4-Demethoxydaunorubicin; Idarubicine; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-92-9. Molecular formula: C26H27NO9. Mole weight: 497.50. | |
| Idarubicin-13C, d3 | Idarubicin-13C, d3 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C25H24NO9[13C]D3. Mole weight: 501.51. | |
| Idarubicin-d4 | Idarubicin-d4 is a labelled Idarubicin. Idarubicin is an anthracycline drug of the antitumor antibiotic family used to treat leukemia. Grade: > 95%. Molecular formula: C26H23NO9D4. Mole weight: 501.53. | |
| Idarubicin Dioxolane Hydrochloride | Idarubicin Dioxolane Hydrochloride is a possible impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: (7S,9S)-7-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-9-(2-methyl-1,3-dioxolan-2-yl)-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride. Molecular formula: C28H31NO10.HCl. Mole weight: 578.01. | |
| Idarubicin hydrochloride | Idarubicin hydrochloride is an anthracycline antileukemic agent. It inhibits the topoisomerase II interfering with the replication of DNA and RNA transcription. Idarubicin hydrochloride inhibits the growth of bacteria and yeasts. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Demethoxydaunorubicin hydrochloride. CAS No. 57852-57-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17381. | |
| Idarubicin hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-25mg. Molecular Weight 497.49. See USA prepack pricing. |  |
| Idarubicin hydrochloride | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C26H27NO9. CAS No. 58957-92-9. Prepack ID 63240268-10mg. Molecular Weight 497.49. See USA prepack pricing. | |
| Idarubicin Hydrochloride | Orally active anthracycline; analog of Daunorubicin. Antineoplastic. Group: Biochemicals. Alternative Names: (7S,9S)-Hydrochloride; Idamycin; NSC 256439; Zavedos. Grades: Highly Purified. CAS No. 57852-57-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Idarubicin Hydrochloride | Idarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Uses: Antibiotics, antineoplastic. Synonyms: (7S,9S)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione Hydrochloride; 4-DMD HCl; 4-Demethoxydaunorubicin Hydrochloride; Idamycin; NSC 256439; Zavedos; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: >98%. CAS No. 57852-57-0. Molecular formula: C26H28ClNO9. Mole weight: 533.95. | |
| Idarubicin Impurity 2 | Idarubicin Impurity 2 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Molecular formula: C28H31NO10. Mole weight: 541.55. | |
| Idarubicin Impurity 4 | Idarubicin Impurity 4 is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,12-dihydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,9-dihydroxy-7-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (7S-cis)-. CAS No. 85440-44-4. Molecular formula: C28H26F3NO9. Mole weight: 577.51. | |
| Idarubicin Isomer | Idarubicin Isomer is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-; 4-Demethoxydaunorubicin, beta; 4-Demethoxy-7,9-di-epi-daunorubicin, beta; 7-O-β-Daunosaminyl-4-demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-. Grade: ≥95%. CAS No. 58957-93-0. Molecular formula: C26H27NO9. Mole weight: 497.49. | |
| Idarubicin Isomer hydrochloride | Idarubicin Isomer hydrochloride is an impurity of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. Synonyms: (7S,9S)-9-Acetyl-7-(((2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Idarubicin Impurity 6; (1S,3S)-3-Acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranoside hydrochloride; (7S-cis)-9-Acetyl-7-((3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione hydrochloride; 5,12-Naphthacenedione, 9-acetyl-7-[(3-amino-2,3,6-trideoxy-β-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S,9S)-, hydrochloride (1:1); 7-O-β-Daunosaminyl-4-demethoxydaunomycinone hydrochloride; Daunomycinone, 7-O-β-daunosaminyl-4-demethoxy-, hydrochloride. CAS No. 60660-72-2. Molecular formula: C26H27NO9.HCl. Mole weight: 533.96. | |
| Idarubicinol | Idarubicinol is the alcohol analog of Idarubicin, which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor. It is also an analog of Daunorubicin. Synonyms: 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-, (7S,9S)-; (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1S)-1-hydroxyethyl]-5,12-naphthacenedione; 5,12-Naphthacenedione, 7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(1-hydroxyethyl)-, [7S-[7α,9α,9(R*)]]-; 13-Dihydroidarubicin; 4-Demethoxydaunorubicinol; Antibiotic FCE 22723. Grade: > 95%. CAS No. 86189-66-4. Molecular formula: C26H29NO9. Mole weight: 499.52. | |
| Idarubicinol-13C, d3 | Idarubicinol-13C, d3 is a labelled nalogue of Idarubicinol. Grade: > 95%. Molecular formula: C26H26NO9D3. Mole weight: 503.53. | |
| Idarubicinol-d4 | Idarubicinol-d4 is a labelled Idarubicinol. Synonyms: Idarubicinol-d4 (Mixture of Diastereomers); (7S,9S)-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-naphthacenedione-d4; [7S-[7α,9α,9(R*)]]-7-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopy. Grade: > 95%. Molecular formula: C26H25NO9D4. Mole weight: 503.55. | |
| Idarubicinol (Mixture of Diastereomers) | Idarubicinol (Mixture of Diastereomers). Group: Biochemicals. Alternative Names: (7S,9S)-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-[(1R*)-1-hydroxyethyl]-5,12-Naphthacenedione; [7S-[7α, 9α, 9(R*)]]-7-[(3-amino-2, 3, 6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7, 8, 9, 10-tetrahydro-6, 9, 11-trihydroxy-9-(1-hydroxyethyl)-5, 12-Naphthacenedione; 13-Dihydroidarubicin; 4-Demethoxydaunorubicino l; Antibiotic FCE 22723. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C26H29NO9, Molecular Weight: 499.51. US Biological Life Sciences. | Worldwide |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. Grade: ≥95%. CAS No. 60660-75-5. Molecular formula: C20H16O7. Mole weight: 368.34. | |
| Idasanutlin | Idasanutlin (RG7388) is a potent and selective MDM2 antagonist, inhibiting p53-MDM2 binding, with an IC50 of 6 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG7388. CAS No. 1229705-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15676. | |
| Idasanutlin | Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Synonyms: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. Grade: >98%. CAS No. 1229705-06-9. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. | |
| Idazoxan | Idazoxan is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, and alpha2-adrenoceptor antagonist used in trials studying the basic science of molecular imaging, Alzheimer's disease, and major depressive disorder. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-; 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; 2-Imidazoline, 2-(1,4-benzodioxan-2-yl)-; (±)-Idazoxan; dl-Idazoxan; Racemic idazoxan. Grade: 95%. CAS No. 79944-58-4. Molecular formula: C11H12N2O2. Mole weight: 204.23. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 79944-56-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Idazoxan hydrochloride | Idazoxan hydrochloride is the hydrochloride salt of idazoxan, which is an I2 imidazoline receptor agonist, I1 imidazoline receptor antagonist, as well as an alpha2-adrenoceptor antagonist. It is selective for α2- over α1-receptors. It is useful for the treatment of parkinsonian and schizophrenia. Synonyms: 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, hydrochloride (1:1); 1H-Imidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-, monohydrochloride; (±)-Idazoxan monohydrochloride; 2-(2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride; RX 781094; RX 781094A. Grade: ≥98%. CAS No. 79944-56-2. Molecular formula: C11H13ClN2O2. Mole weight: 240.69. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinsons disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RX 781094 hydrochloride. CAS No. 79944-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-14561A. | |
| Idazoxan hydrochloride | Idazoxan hydrochloride. Uses: For analytical and research use. CAS No. 79944-56-2. Mole weight: 240.69. Catalog: AP79944562. | |
| IDE1 | IDE1 is an inducer of definitive endoderm 1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160927-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100533. | |
| IDE 2 | IDE2 is a small molecule cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) by activating the TGF-βsignaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1136466-93-7. Pack Sizes: 1 mg. Product ID: HY-100534. | |
| Idebenone | Ubiquinone derivative with protective effects against cerebral ischemia. Nootropic. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; Avan; CV 2619; Daruma; Idebenone; Mnesis. Grades: Highly Purified. CAS No. 58186-27-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Idebenone | Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM)[1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier. Uses: Scientific research. Category: Signaling pathways. CAS No. 58186-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0303. | |
| Idebenone | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Synonyms: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. Grade: >98%. CAS No. 58186-27-9. Molecular formula: C19H30O5. Mole weight: 338.44. | |
| Idebenone > 98% | Idebenone > 98%. CAS No. 58186-27-9. |  CA, FL & NJ |
| Idebenone-d6 | Idebenone-d6 is a labelled Idebenone. Idebenone is a synthetic analogue of coenzyme Q10. It is indicated for the treatment of Alzheimer's disease. Synonyms: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione-d6. Grade: > 95%. Molecular formula: C19H24O5D6. Mole weight: 344.48. | |
| Idebenone-D-Glucuronide | Idebenone-D-Glucuronide is a compound used for studying neurodegenerative ailments, most notably Alzheimer's and Parkinson's. Grade: > 95%. Molecular formula: C25H38O11. Mole weight: 514.58. | |
| Idebenone Glucuronide | Idebenone Glucuronide is the glucuronoside conjugate of Idebenone, an ubiquinone derivative with protective effects against cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid; Avan Glucuronide; CV 2619 Glucuronide; Daruma Glucuronide; Mnesis Glucuronide; Idebenone β-D-Glucuronide. Molecular formula: C25H38O11. Mole weight: 514.56. | |
| Idebenone Glucuronide-13C,d3 | Idebenone Glucuronide-13C,d3. Group: Biochemicals. Alternative Names: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2413CH35D3O11, Molecular Weight: 518.57. US Biological Life Sciences. | Worldwide |
| Idebenone Glucuronide-13C,d3 | The isotope-labelled idebenone glucuronide is a glucuronide conjugate of idebenone. Idebenone is a ubiquinone derivative with protective effects on cerebral ischemia. Synonyms: 2-(10-Hydroxydecyl)-5,6-methoxy-3-methyl-2,5-cyclohexadiene-1,4-dione β-D-Glucopyranosiduronic Acid-13C,d3; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone β-D-Glucopyranosiduronic Acid-13C,d3; Avan Glucuronide-13C,d3; CV 2619 Glucuronide-13C,d3; Daruma Glucuronide-13C,d3; Mnesis Glucuronide-13C,d3. Molecular formula: C24[13C]H35D3O11. Mole weight: 518.57. | |
| Idebenone Impurity1 | Idebenone Impurity1. Uses: For analytical and research use. Molecular formula: C19H31NO4. Mole weight: 337.46. Catalog: APB11274. | |
| Idebenone Impurity10 | Idebenone Impurity10. Uses: For analytical and research use. Molecular formula: C20H32O5. Mole weight: 352.47. Catalog: APB11279. | |
| Idebenone Impurity11 | Idebenone Impurity11. Uses: For analytical and research use. Molecular formula: C18H28O4. Mole weight: 308.42. Catalog: APB11282. | |
| Idebenone Impurity12 | Idebenone Impurity12. Uses: For analytical and research use. CAS No. 116460-82-3. Molecular formula: C18H28O4. Mole weight: 308.42. Catalog: APB116460823. | |
| Idebenone Impurity13 | Idebenone Impurity13. Uses: For analytical and research use. Molecular formula: C19H30O6. Mole weight: 354.44. Catalog: APB11280. | |
| Idebenone Impurity14 | Idebenone Impurity14. Uses: For analytical and research use. CAS No. 77712-29-9. Molecular formula: C19H32O4. Mole weight: 324.4. Catalog: APB77712299. | |
| Idebenone Impurity15 | Idebenone Impurity15. Uses: For analytical and research use. CAS No. 634-85-5. Molecular formula: C6HCl3O2. Mole weight: 211.42. Catalog: APB634855. | |
| Idebenone Impurity16 | Idebenone Impurity16. Uses: For analytical and research use. CAS No. 38969-08-3. Molecular formula: C8H6Br2O2. Mole weight: 293.94. Catalog: APB38969083. | |
| Idebenone Impurity17 | Idebenone Impurity17. Uses: For analytical and research use. CAS No. 87405-27-4. Molecular formula: C8H6Br2O2. Mole weight: 293.94. Catalog: APB87405274. | |
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