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| Product | Description | |
|---|---|---|
| Ibandronate sodium monohydrate | Ibandronate sodium monohydrate. Group: Biochemicals. Alternative Names: BM-21.0955; Bondronat. Grades: Highly Purified. CAS No. 138926-19-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H24NNaO8P2. US Biological Life Sciences. |  Worldwide |
| Ibandronate Sodium Monohydrate | Ibandronate Sodium Monohydrate (BM-210955; RPR-102289A) is an orally active, selective inhibitor of farnesyl pyrophosphate synthase (FPP synthase). Ibandronate Sodium Monohydrate can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases (such as RAS, RHO family proteins), induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium Monohydrate inhibits tumor cell proliferation (such as ER+ breast cancer cells), promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium Monohydrate is used in the study of osteoporosis and bone metastatic tumors (such as breast cancer bone metastasis)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BM-210955; RPR-102289A. CAS No. 138926-19-9. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0515. |  |
| Ibandronate Sodium Monohydrate | Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner. Synonyms: BM-21.0955. Grade:>98%. CAS No. 138926-19-9. Molecular formula: C9H23NO7P2.Na.H2O. Mole weight: 360.23. |  |
| Ibandronate sodium salt | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-1g. Molecular Weight 341.21. See USA prepack pricing. |  |
| Ibandronate sodium salt | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H22NNaO7P2. CAS No. 138926-19-9. Prepack ID 46946205-5g. Molecular Weight 341.21. See USA prepack pricing. | |
| Ibandronic acid | Ibandronic acid. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; [1-Hydroxy-3- (methylpentylamino) propylidene] bisphosphonic acid; BPH 24. Grades: Highly Purified. CAS No. 114084-78-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C9H23NO7P2. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid | Ibandronic acid is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. Synonyms: P,P'-[1-Hydroxy-3-(methylpentylamino)propylidene]bisphosphonic Acid; [1-Hydroxy-3-(methylpentylamino)propylidene]bisphosphonic Acid; BPH 24; Ibandronate; 1-Hydroxy-3-(methylpentylamino)propylidene]diphosphonic Acid. Grade: >98%. CAS No. 114084-78-5. Molecular formula: C9H23NO7P2. Mole weight: 319.23. | |
| Ibandronic acid-[d3] | Ibandronic acid-[d3] is the labelled analogue of Ibandronic acid, which is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis. Synonyms: Ibandronic acid D3; P,P'-[1-Hydroxy-3-[(methyl-d3)pentylamino]propylidene]bisphosphonic Acid; BPH 24-d3; Ibandronate-d3; [1-Hydroxy-3-[(methyl-d3)pentylamino]propylidene]diphosphonic Acid. Grade: ≥95%; ≥95% atom D. CAS No. 1130899-41-0. Molecular formula: C9H20D3NO7P2. Mole weight: 322.25. | |
| Ibandronic Acid-d3 | Labeled Ibandronic Acid. A bisphosphonate antiresorptive agent. Bone resorption inhibitor. Group: Biochemicals. Alternative Names: P, P'- [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] bisphosphonic Acid; BPH 24-d3; Ibandronate-d3; [1-Hydroxy-3- [ (methyl-d3) pentylamino] propylidene] diphosphonic Acid. Grades: Highly Purified. CAS No. 1130899-41-0. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Ibandronic Acid Impurity HCl | Ibandronic Acid Impurity HCl is an intermediate in the preparation of Ibandronic Acid. Synonyms: 3-(N-Methyl-N-pentylamino)propionic Acid Hydrochloride; N-Methyl-N-pentyl-β-alanine Hydrochloride; Ibanic Acid Hydrochloride; Ibandronate Related Compound A. Grade: > 95%. CAS No. 625120-81-2. Molecular formula: C9H20NO2Cl. Mole weight: 209.72. | |
| Ibandronic Acid N-(2-Methylbutyl) Impurity | Ibandronic Acid N-(2-Methylbutyl) Impurity. Grade: > 95%. Molecular formula: C9H23NO7P2. Mole weight: 319.23. | |
| IBC 293 | IBC 293, a cell-permeable niacin triazolo derivative, is a potent and highly selective agonist for human orphan G-protein-coupled receptor GPR109b/HM74 expressed in adipocytes with EC50 value of 400 nM. It is selective for GPR109B over niacin receptor GPR109A and β-adrenergic receptor. It inhibits cAMP elevation induced by isoproterenol and forskolin in freshly isolated human adipocytes and GPR109b-expressing CHO cells. It also inhibits forskolin-stimulated cAMP release in Chinese hamster ovary cells. It also inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes. It may be relevant to atherosclerosis and dyslipidemia. Synonyms: IBC 293; IBC293; IBC-293. 1-Isopropyl-1,2,3-benzotriazole-5-carboxylic acid; 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid. Grade: ≥99% by HPLC. CAS No. 306935-41-1. Molecular formula: C10H11N3O2. Mole weight: 205.22. | |
| IBC 293 | IBC 293. Group: Biochemicals. Grades: Purified. CAS No. 306935-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ibentatug | Ibentatug is an anti-CSP1 human IgG1 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 2767983-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990744. | |
| Iberdomide | Iberdomide (CC-220) is a cereblon modulator with an IC50 of 60 nM. It has antitumor and immunomodulatory activities. Synonyms: (3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione; CC-220; CC220; CC 220; Iberdomide. CAS No. 1323403-33-3. Molecular formula: C25H27N3O5. Mole weight: 449.5. | |
| Iberdomide | Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ~150?nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-220. CAS No. 1323403-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101291. | |
| Iberdomide (CC-220) | Iberdomide (CC-220) is a novel oral immunomodulatory compound that targets cereblon, part of the CRL4CRBN E3 ubiquitin ligase complex, with an IC50 of 60 nM in a competitive TR-FRET assay. Iberdomide (CC-220) induces apoptosis with antitumor and immunostimulatory activities. Group: Inhibitors. CAS No. 1323403-33-3. Pack Sizes: 2mg. Product ID: S8760. Formula: C25H27N3O5. Smiles: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3OCC4=CC=C(C=C4)CN5CCOCC5. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| Iberin | Iberin. Group: Biochemicals. Alternative Names: 1-Isothiocyanato-3-(methylsulfinyl)-propane; 3-Methylsulfinylpropyl Isothiocyanate; NSC 321801. Grades: Highly Purified. CAS No. 505-44-2. Pack Sizes: 5mg. Molecular Formula: C5H9NOS2, Molecular Weight: 163.26. US Biological Life Sciences. | Worldwide |
| Iberin | Iberin, a naturally occurring member of isothiocyanate family found in cruciferous plants, inhibits cell survival (IC50 = 2.3 μM in HL60 cell). Synonyms: 1-isothiocyanato-3-methylsulfinylpropane; 1-isothiocyanato-3-(methylsulfinyl)propane; 1-isothiocyanato-3-(methylsulphinyl)propane; iberin; IMSP. CAS No. 505-44-2. Molecular formula: C5H9NOS2. Mole weight: 163.26. | |
| Iberiotoxin | Iberiotoxin, a toxin extracted from the venom of the scorpion Buthus tamulus, is a selective blocker of high-conductance Ca2+-activated K+ channel. Synonyms: Pyr-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-Gln-OH (Disulfide bridge: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35); 5-Oxo-L-prolyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-valyl-L-α-aspartyl-L-cysteinyl-L-seryl-L-valyl-L-seryl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-tryptophyl-L-seryl-L-valyl-L-cysteinyl-L-lysyl-L-α-aspartyl-L-leucyl-L-phenylalanylglycyl-L-valyl-L-α-aspartyl-L-arginylglycyl-L-lysyl-L-cysteinyl-L-methionylglycyl-L-lysyl-L-lysyl-L-cysteinyl-L-arginyl-L-cysteinyl-L-tyrosyl-L-glutamine cyclic (7→28),(13→33),(17→35)-tris(disulfide); 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic acid-21-L-phenylalanine-22-glycine-23-L-valine-24-L-aspartic acid-30-glycine-37-L-glutamine-charybdotoxin. Grade: ≥96% by HPLC. CAS No. 129203-60-7. Molecular formula: C179H274N50O55S7. Mole weight: 4230.85. | |
| Iberiotoxin | Iberiotoxin is a toxin isolated from Buthus tamulus scorpion venom. Iberiotoxin is a selective high conductance high conductance Ca2+-activated K+ channel inhibitor with a Kd of ~1 nM. Iberiotoxin does not block other types of voltage-dependent ion channels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 129203-60-7. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P0190. | |
| Iberiotoxin trifluoroacetate salt | Iberiotoxin is a 37-amino acid peptide toxin purified from the scorpion Buthus tamulus. It acts as a blocker of high conductance Ca(2+)-activated K+ channels at nanomolar concentrations. Grade: ≥95%. CAS No. 182897-30-9. Mole weight: 4230.9. | |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Synonyms: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. Grade: >98%. CAS No. 1300031-49-5. Molecular formula: C23H21N5O3. Mole weight: 415.453. | |
| I-BET151 | I-BET151 (GSK1210151A) is a BET bromodomain inhibitor which inhibits BRD4, BRD2, and BRD3 with pIC50 of 6.1, 6.3, and 6.6, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK1210151A. CAS No. 1300031-49-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13235. | |
| I-BET 151 dihydrochloride | The hydrochloride salt form of I-BET 151, which has been found to be a BET bromodomain inhibitor and exhibit activities against human and murine MLL-fusion leukaemic cell lines. Synonyms: I-BET 151 dihydrochloride; I BET 151 dihydrochloride; IBET 151 dihydrochloride; IBET151 dihydrochloride; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydroxy-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one dihydrochloride. Grade: ≥98% by HPLC. CAS No. 1883545-47-8. Molecular formula: C23H21N5O3.2HCl. Mole weight: 488.37. | |
| I-BET567 | I-BET567 is a potent and orally active pan-BET candidate inhibitor with pIC50s of 6.9 and 7.2 against BRD4 BD1 and BD2, respectively. It has been shown to be effective in mouse models of oncology and inflammation. Synonyms: 6-Quinolinecarboxamide, 1-acetyl-4-[(5-chloro-2-pyrimidinyl)amino]-1,2,3,4-tetrahydro-2-methyl-, (2S,4R)-. Grade: ≥95%. CAS No. 1887237-54-8. Molecular formula: C17H18ClN5O2. Mole weight: 359.81. | |
| Ibezapolstat | Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACX-362E; GLS-362E. CAS No. 1275582-97-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128357. | |
| Ibezapolstat hydrochloride | Ibezapolstat hydrochloride is an active DNA polymerase IIIC inhibitor. Ibezapolstat is used in the research of C. difficile infection (CDI). Synonyms: 6H-Purin-6-one, 2-(((3,4-dichlorophenyl)methyl)amino)-1,7-dihydro-7-(2-(4-morpholinyl)ethyl)-, hydrochloride (1:1). Grade: >98.0%. CAS No. 1275582-98-3. Molecular formula: C18H21Cl3N6O2. Mole weight: 459.76. | |
| IBG1 | IBG1 is a molecular glue degrader targeting BRD2 and BRD4 (DC50: 0.15 nM). IBG1 has no significant degradation effect on its paralogue BRD3. IBG1 can inhibit the growth of cancer cells and can be used in tumor research. (Pink: BRD2/BRD4 Ligand (HY-111139); Black: Linker; Blue: DCAF15 ligand-1 (HY-W037495))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2684292-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153459. | |
| Ibiglustat | Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. In Oct 2016, Genzyme completed a phase II trial in Fabry's disease (Treatment-naïve) in USA, Czech Republic, France, Poland, Russia and the UK. Phase-II clinical trials in Gaucher's disease in USA is on-going. Uses: Fabry's disease; gaucher's disease. Synonyms: Venglustat; GZ-402671; GZ402671; GZ 402671; SSAR402671; SAR-402671; SAR 402671; Genz-682452-AA; GZ-452; Genz-682452; GZ 452; Genz 682452; GZ452; (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate. Grade: 98%. CAS No. 1401090-53-6. Molecular formula: C20H24FN3O2S. Mole weight: 389.49. | |
| Ibiglustat | Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Venglustat; SAR402671; GZ402671. CAS No. 1401090-53-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743. | |
| Ibiglustat (L-Malic acid) | Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid). CAS No. 1629063-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg. Product ID: HY-16743A. | |
| Ibiglustat succinate | Ibiglustat succinate is a glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. Synonyms: Venglustat succinate; Ibiglustat L-malate. CAS No. 1629063-78-0. Molecular formula: C24H30FN3O7S. Mole weight: 523.6. | |
| Ibipinabant | Ibipinabant is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2), respectively. Uses: Cannabinoid receptor cb1 antagonists. Synonyms: BMS-646256; BMS646256; BMS 646256; SLV-319; SLV 319; SLV319; JD-5001; JD 5001; JD5001; Ibipinabant.3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4S-phenyl-1H-pyrazole-1-carboximidamide. Grade: ≥98%. CAS No. 464213-10-3. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.40. | |
| IBL-302 | IBL-302 (AMU302) is an orally available dual-signaling inhibitor of PIM and PI3K/AKT/mTOR with activity against breast cancer and neuroblastoma. IBL-302 demonstrated in vivo efficacy in a nude mouse xenograft model, inhibiting trastuzumab (HY-P9907) resistance challenges. IBL-302 also enhances the effects of common cytotoxic chemotherapy drugs cisplatin (HY-17394), doxorubicin (HY-15142A), and etoposide (HY-13629)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMU302. CAS No. 1414455-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-157169. | |
| IBMX | IBMX is an inhibitor of cAMP and cGMP phosphodiesterases. IBMX was shown to promote differentiation of 3T3-L1 cells in combination with insulin and dexamethasone. It also induces neural transdifferentiation of mesenchymal stem cells (MSCs) through downregulation of the NRSF. Uses: Phosphodiesterase inhibitors. Synonyms: 3-Isobutyl-1-methylxanthine; isobutylmethylxanthine; 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione. Grade: >98%. CAS No. 28822-58-4. Molecular formula: C10H14N4O2. Mole weight: 222.24. | |
| IBMX | IBMX Inhibitor. Uses: Scientific use. Product Category: T1713. CAS No. 28822-58-4. |  |
| IBMX | IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| IBMX | IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine. CAS No. 28822-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12318. | |
| IBMX (3-Isobutyl-1-methylxanthine) | IBMX (Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively. It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist. Group: Inhibitors. Alternative Names: Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine. CAS No. 28822-58-4. Pack Sizes: 5mg. Product ID: S5836. Formula: C10H14N4O2. Smiles: CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| IBMX (3-Isobutyl-1-methylxanthine) | 3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| IBMX (Standard) | IBMX (Standard) is the analytical standard of IBMX. This product is intended for research and analytical applications. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Isobutyl-1-methylxanthine (Standard); Isobutylmethylxanthine (Standard). CAS No. 28822-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12318R. | |
| IBOA | IBOA. Mole weight: 208. |  |
| Ibodutant | Ibodutant is a tachykinin receptor antagonist. It selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. It is a candidate drug for irritable bowel syndrome diarrhea. It was developed by The Menarini Group. It is in the clinical phase III. Uses: Ibodutant is a candidate drug for irritable bowel syndrome diarrhea. Synonyms: MEN-15596; MEN 15596; MEN15596; Ibodutant 6-Methyl-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide; (R)-6-methyl-N-(1-((1-oxo-3-phenyl-1-(((1-((tetrahydro-2H-pyran-4-yl)methyl)piperidi. Grade: 98%. CAS No. 522664-63-7. Molecular formula: C37H48N4O4S. Mole weight: 644.87. | |
| IBOMA | IBOMA. Mole weight: 222. | |
| I-BOP | I-BOP is a potent TP receptor agonist that induces platelet aggregation and vascular smooth muscle contraction. Synonyms: (Z)-7-[(1S,2R,3R,4R)-3-[(E,3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid. Grade: ≥95%. CAS No. 128719-90-4. Molecular formula: C23H29IO5. Mole weight: 512.4. | |
| Ibopamine | Ibopamine, the prodrug of epinine, is a sympathomimetic drug used in ophthalmology. It induces mydriasis. It acts as an agonist on Dopamine receptor D1 and α-adrenergic receptors and has been studied for the treatment of congestive heart failure. Synonyms: 4-(2-(methylamino)ethyl)-1,2-phenylene bis(2-methylpropanoate); 4-(2-(Methylamino)ethyl)-o-phenylene diisobutyrate; SB-7505; Propanoic acid, 2-methyl-, 4-(2-(methylamino)ethyl)-1,2-phenylene ester; Diisobutyric acid 4-[2-(methylamino)ethyl]-o-phenylene ester; 2-Methylpropanoic Acid 4-[2-(Methylamino)ethyl]-1,2-phenylene Ester. Grade: ≥95%. CAS No. 66195-31-1. Molecular formula: C17H25NO4. Mole weight: 307.38. | |
| Ibopamine Hydrochloride | Ibopamine Hydrochloride, the prodrug of epinine, is a sympathomimetic drug used in ophthalmology. It induces mydriasis. It acts as an agonist on Dopamine receptor D1 and α-adrenergic receptors and has been studied for the treatment of congestive heart failure. Synonyms: 2-Methylpropanoic Acid 1,1'-[4-[2-(Methylamino)ethyl]-1,2-phenylene] Ester Hydrochloride; 3,4-Di-O-isobutyrylepinine Hydrochloride; Inopamil; Scandine. Grade: ≥95%. CAS No. 75011-65-3. Molecular formula: C17H26ClNO4. Mole weight: 343.85. | |
| Ibotenic acid | 1mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C5H6N2O4. CAS No. 2552-55-8. Prepack ID 80949608-1mg. Molecular Weight 158.11. See USA prepack pricing. | |
| Ibotenic acid | Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. Synonyms: (+/-)-Ibotenic acid; DL-Ibotenic acid. Grade: ≥98% by HPLC. CAS No. 2552-55-8. Molecular formula: C5H6N2O4. Mole weight: 158.11. | |
| Ibotenic acid | Ibotenic acid. Alternative Names: (±)-Ibotenic Acid. CAS No. 2552-55-8. Purity: >98.0%. Product ID: FFC-AR-2552558. Molecular formula: C5H6N2O4. Mole weight: 158.11. IUPAC Name: 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Ibotenic acid | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2311. | |
| Ibotenic Acid | Ibotenic acid is a conformationally restricted analog of glutamic acid and a a potent Glu agonist.A highly potent agonist ofnMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts. Group: Biochemicals. Alternative Names: a-Amino-3-hydroxy-5-isoxazoleacetic acid;; (2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid; Glutamate Receptor Agonist; NSC 204850. Grades: Highly Purified. CAS No. 2552-55-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C?H?N?O?, Molecular Weight: 158.11. US Biological Life Sciences. | Worldwide |
| Iboxamycin | Iboxamycin is orally bioavailable, safe and effective in treating both Gram-positive and Gram-negative bacterial infections in mice. CAS No. 2640000-92-4. Molecular formula: C22H39ClN2O6S. Mole weight: 495.07. | |
| IBR2 | IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313526-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103710. | |
| iBRD4-BD1 | iBRD4-BD1 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 can be used for the research of inflammation and oncology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2839318-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151594. | |
| I-BRD9 | I-BRD9 is a selective cellular chemical probe of bromodomain-containing protein 9 (BRD9) with pIC50 value of 7.3 μM. I-BRD9 has high selectivity for bromodomain and extra terminal domain (BET) family and highly homologous bromodomain-containing protein 7 (BRD7). I-BRD9 can be used to identify genes regulated by BRD9 in Kasumi-1 cells involved in oncology and immune response pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1714146-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18975. | |
| I-BRD9 | I-BRD9, as a selective cell active chemical probe for BRD9 (pIC50 = 7.3), it exhibits 200-fold selectivity for bromodomain containing protein 9 over the highly homologous BRD7 bromodomain, >70-fold selectivity for BRD9 over a panel of 34 other bromodomain. Synonyms: N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamideI-BRD9; I-BRD-9; I-BRD 9N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamideG. CAS No. 1714146-59-4. Molecular formula: C22H22F3N3O3S2. Mole weight: 497.55. | |
| Ibrexafungerp | Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-. Grade: 98%. CAS No. 1207753-03-4. Molecular formula: C44H67N5O4. Mole weight: 730.03. | |
| Ibrexafungerp | Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 3118; SCY-078. CAS No. 1207753-03-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107126. | |
| Ibrexafungerp citrate | Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 3118 citrate; SCY-078 citrate. CAS No. 1965291-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107126A. | |
| Ibrexafungerp Citrate | Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). Grade: 98%. CAS No. 1965291-08-0. Molecular formula: C50H75N5O11. Mole weight: 922.17. | |
| Ibrolipim | Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NO-1886. CAS No. 133208-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117549. | |
| Ibrutinib | Ibrutinib Inhibitor. Uses: Scientific use. Product Category: T1835. CAS No. 936563-96-1. | |
| Ibrutinib | Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PCI-32765. CAS No. 936563-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10997. | |
| Ibrutinib | Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Synonyms: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grade: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
| Ibrutinib-biotin | Ibrutinib-biotin is a probe that consists of Ibrutinib connected to biotin via a long chain linker with an IC50 of 0.755-1.02 nM for BTK. (Extracted from patent WO2014059368A1 Compound 1-5). Synonyms: Ibrutinib-biotin-1; N-(4-{[(2E)-4-{(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl}-4-oxo-2-buten-1-yl](methyl)amino}butyl)-N'-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}pentanediamide. Grade: ≥98%. CAS No. 1599432-18-4. Molecular formula: C56H80N12O9S. Mole weight: 1097.37. | |
| Ibrutinib-biotin | Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599432-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100342. | |
| Ibrutinib-d4 | Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton s tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences. | Worldwide |
| Ibrutinib-[d5] | Ibrutinib-[d5] is the labelled analogue of Ibrutinib. Ibrutinib can be used to treat such cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström macroglobulinemia. Synonyms: Ibrutinib D5. Grade: 98% by HPLC; 98% atom D. CAS No. 1553977-17-5. Molecular formula: C25H19D5N6O2. Mole weight: 445.53. | |
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