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| Product | Description | |
|---|---|---|
| I-BET762 carboxylic acid | I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. Alternative Names: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2. CAS No. 1300019-38-8. Molecular formula: C20H17ClN4O3. Mole weight: 396.83. |  |
| Ibezapolstat | Ibezapolstat (ACX-362E) is a first-in-class, orally active DNA polymerase IIIC (pol IIIC) inhibitor, with a Ki of 0.325 μM for the DNA pol IIIC from C. difficile. Ibezapolstat is developed for the research of C. difficile infection(CDI)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACX-362E; GLS-362E. CAS No. 1275582-97-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128357. |  |
| IBG1 | IBG1 is a molecular glue degrader targeting BRD2 and BRD4 (DC50: 0.15 nM). IBG1 has no significant degradation effect on its paralogue BRD3. IBG1 can inhibit the growth of cancer cells and can be used in tumor research. (Pink: BRD2/BRD4 Ligand (HY-111139); Black: Linker; Blue: DCAF15 ligand-1 (HY-W037495))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2684292-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153459. | |
| Ibiglustat | Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. In Oct 2016, Genzyme completed a phase II trial in Fabry's disease (Treatment-naïve) in USA, Czech Republic, France, Poland, Russia and the UK. Phase-II clinical trials in Gaucher's disease in USA is on-going. Uses: Fabry's disease; gaucher's disease. Alternative Names: Venglustat; GZ-402671; GZ402671; GZ 402671; SSAR402671; SAR-402671; SAR 402671; Genz-682452-AA; GZ-452; Genz-682452; GZ 452; Genz 682452; GZ452; (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate. Grades: 98%. CAS No. 1401090-53-6. Molecular formula: C20H24FN3O2S. Mole weight: 389.49. | |
| Ibiglustat | Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Venglustat; SAR402671; GZ402671. CAS No. 1401090-53-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16743. | |
| Ibiglustat (L-Malic acid) | Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid). CAS No. 1629063-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg. Product ID: HY-16743A. | |
| IBL-302 | IBL-302 (AMU302) is an orally available dual-signaling inhibitor of PIM and PI3K/AKT/mTOR with activity against breast cancer and neuroblastoma. IBL-302 demonstrated in vivo efficacy in a nude mouse xenograft model, inhibiting trastuzumab (HY-P9907) resistance challenges. IBL-302 also enhances the effects of common cytotoxic chemotherapy drugs cisplatin (HY-17394), doxorubicin (HY-15142A), and etoposide (HY-13629)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMU302. CAS No. 1414455-21-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-157169. | |
| IBMX | IBMX Inhibitor. Uses: Scientific use. Product Category: T1713. CAS No. 28822-58-4. |  |
| IBMX | IBMX. Group: Biochemicals. Grades: Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. |  Worldwide |
| IBMX | IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Isobutyl-1-methylxanthine; Isobutylmethylxanthine. CAS No. 28822-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12318. | |
| IBMX (3-Isobutyl-1-methylxanthine) | 3-isobutyl-1-methylxanthine (IBMX) is a nonselective inhibitor of cAMP and cGMP phosphodiesterases (PDEs). Research studies show that IBMX inhibits many members of the PDE family, with the exceptions of PDE8A, PDE8B, and PDE9 (1-4). Treatment of cells with IBMX promotes accumulation of cAMP and cGMP, which leads to activation of cyclic- nucleotide- regulated protein kinases (5,6). Additional research indicates that IBMX can promote neuronal progenitor cell maturation in vitro (7). Group: Biochemicals. Grades: Highly Purified. CAS No. 28822-58-4. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| IBMX (3-Isobutyl-1-methylxanthine) | IBMX (Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine) is a nonspecific inhibitor of phosphodiesterase (PDE) with IC50 values of 6.5±1.2, 26.3±3.9 and 31.7±5.3 μM for PDE3, 4 and 5 respectively. It may enhance the intracellular cAMP levels and also acts as an adenosine (A1) receptor antagonist. Group: Inhibitors. Alternative Names: Isobutylmethylxanthine, 1-Methyl-3-Isobutylxanthine. CAS No. 28822-58-4. Pack Sizes: 5mg. Product ID: S5836. Formula: C10H14N4O2. Smiles: CC(C)CN1C2=C(C(=O)N(C1=O)C)NC=N2. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| IBMX (Standard) | IBMX (Standard) is the analytical standard of IBMX. This product is intended for research and analytical applications. IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Isobutyl-1-methylxanthine (Standard); Isobutylmethylxanthine (Standard). CAS No. 28822-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12318R. | |
| IBOA | IBOA. Mole weight: 208. |  |
| IBOMA | IBOMA. Mole weight: 222. | |
| Ibotenic acid | Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2311. | |
| Ibotenic acid | 1mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C5H6N2O4. CAS No. 2552-55-8. Prepack ID 80949608-1mg. Molecular Weight 158.11. See USA prepack pricing. |  |
| Ibotenic acid | Ibotenic acid. Alternative Names: (±)-Ibotenic Acid. CAS No. 2552-55-8. Purity: >98.0%. Product ID: FFC-AR-2552558. Molecular formula: C5H6N2O4. Mole weight: 158.11. IUPAC Name: 2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Ibotenic acid | Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. Alternative Names: (+/-)-Ibotenic acid; DL-Ibotenic acid. Grades: ≥98% by HPLC. CAS No. 2552-55-8. Molecular formula: C5H6N2O4. Mole weight: 158.11. | |
| Ibotenic Acid | Ibotenic acid is a conformationally restricted analog of glutamic acid and a a potent Glu agonist.A highly potent agonist ofnMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts. Group: Biochemicals. Alternative Names: a-Amino-3-hydroxy-5-isoxazoleacetic acid;; (2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid; Glutamate Receptor Agonist; NSC 204850. Grades: Highly Purified. CAS No. 2552-55-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C?H?N?O?, Molecular Weight: 158.11. US Biological Life Sciences. | Worldwide |
| IBR2 | IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313526-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103710. | |
| iBRD4-BD1 | iBRD4-BD1 is selective BRD4 bromodomain inhibitor. iBRD4-BD1 has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 can be used for the research of inflammation and oncology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2839318-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151594. | |
| I-BRD9 | I-BRD9 is a selective cellular chemical probe of bromodomain-containing protein 9 (BRD9) with pIC50 value of 7.3 μM. I-BRD9 has high selectivity for bromodomain and extra terminal domain (BET) family and highly homologous bromodomain-containing protein 7 (BRD7). I-BRD9 can be used to identify genes regulated by BRD9 in Kasumi-1 cells involved in oncology and immune response pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1714146-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18975. | |
| Ibrexafungerp | Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Alternative Names: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-. Grades: 98%. CAS No. 1207753-03-4. Molecular formula: C44H67N5O4. Mole weight: 730.03. | |
| Ibrexafungerp | Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 3118; SCY-078. CAS No. 1207753-03-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-107126. | |
| Ibrexafungerp citrate | Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 3118 citrate; SCY-078 citrate. CAS No. 1965291-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107126A. | |
| Ibrexafungerp Citrate | Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Alternative Names: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). Grades: 98%. CAS No. 1965291-08-0. Molecular formula: C50H75N5O11. Mole weight: 922.17. | |
| Ibrolipim | Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NO-1886. CAS No. 133208-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117549. | |
| Ibrutinib | Ibrutinib Inhibitor. Uses: Scientific use. Product Category: T1835. CAS No. 936563-96-1. | |
| Ibrutinib | Ibrutinib is a potent and selective BTK inhibitor (IC50=0.5 nM). Alternative Names: PCI-32765; PCI 32765; (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: ≥95%. CAS No. 936563-96-1. Molecular formula: C25H24N6O2. Mole weight: 440.50. | |
| Ibrutinib | Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PCI-32765. CAS No. 936563-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10997. | |
| Ibrutinib-biotin | Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599432-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100342. | |
| Ibrutinib-d4 | Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton s tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences. | Worldwide |
| Ibrutinib dimer | Ibrutinib dimer is a Dimer of Ibrutinib. Ibrutinib dimer is an impurity of Ibrutinib[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2031255-23-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136113. | |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Alternative Names: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grades: 95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Alternative Names: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grades: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
| Ibrutinib Impurity 18 | Ibrutinib Impurity 18. Uses: For analytical and research use. Alternative Names: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 1022150-12-4. Molecular formula: C22H22N6O. Mole weight: 386.45. Catalog: APB1022150124. |  |
| Ibrutinib impurity 20 | Ibrutinib impurity 20. Uses: For analytical and research use. CAS No. 1839090-60-6. Molecular formula: C25H24N6O4. Mole weight: 472.51. Catalog: APB1839090606. | |
| Ibrutinib impurity 21 | Ibrutinib impurity 21. Uses: For analytical and research use. Molecular formula: C25H23N5O3. Mole weight: 441.49. Catalog: APB11054. | |
| Ibrutinib impurity 22 | Ibrutinib impurity 22. Uses: For analytical and research use. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. Catalog: APB2031255260. | |
| Ibrutinib Impurity 23 | Ibrutinib Impurity 23. Uses: For analytical and research use. CAS No. 1838132-94-7. Molecular formula: C25H26N6O3. Mole weight: 458.52. Catalog: APB1838132947. | |
| Ibrutinib Impurity 24 | Ibrutinib Impurity 24. Uses: For analytical and research use. CAS No. 2437254-47-0. Molecular formula: C25H24N6O3. Mole weight: 456.51. Catalog: APB2437254470. | |
| Ibrutinib Impurity 31 | Ibrutinib Impurity 31. Uses: For analytical and research use. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethanone. CAS No. 1288338-95-3. Molecular formula: C24H24N6O2. Mole weight: 428.49. Catalog: APB1288338953. | |
| Ibrutinib Impurity 36 | Ibrutinib Impurity 36. Uses: For analytical and research use. Alternative Names: (R)-3-(1-(1-acryloylpiperidin-3-yl)-4-imino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)propanoic acid. Molecular formula: C28H28N6O4. Mole weight: 512.56. Catalog: APB02065. | |
| Ibrutinib Impurity 5 | Ibrutinib Impurity 5. Uses: For analytical and research use. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. CAS No. 1288338-96-4. Molecular formula: C25H25ClN6O2. Mole weight: 476.96. Catalog: APB1288338964. | |
| Ibrutinib Impurity 8 | Ibrutinib Impurity 8. Uses: For analytical and research use. Alternative Names: 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.32. Catalog: APB330786248. | |
| Ibrutinib-MPEA | Ibrutinib-MPEA is an orally active, blood-brain barrier permeable inhibitor of BTK and STAT5. As a derivative of Ibrutinib (HY-10997) conjugated with a PROTAC linker, Ibrutinib-MPEA allows the synthesis of a series of PROTAC molecules. Ibrutinib-MPEA significantly reduces the proliferation of neoplastic mast cells and primary mastocytoma cells by inducing apoptosis and inhibiting IgE-dependent histamine release. Ibrutinib-MPEA is applicable to the research of canine mast cell tumors, cerebral ischemia/reperfusion injury in diabetic mice, and neuroinflammation-related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1710768-30-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-43521. | |
| Ibrutinib (PCI-32765) | Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I. Group: Inhibitors. Alternative Names: PCI-32765. CAS No. 936563-96-1. Pack Sizes: 5mg. Product ID: S2680. Formula: C25H24N6O2. Smiles: C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Ibrutinib (Standard) | Ibrutinib (Standard) is the analytical standard of Ibrutinib. This product is intended for research and analytical applications. Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PCI-32765 (Standard). CAS No. 936563-96-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10997R. | |
| IBS008738 | IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 385425-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112821. | |
| IBT6A | IBT6A is an impurity of Ibrutinib. IBT6A can be used in synthesis of IBT6A Ibrutinib dimer and IBT6A adduct[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1022150-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-13036A. | |
| Ibudilast | Ibudilast. Alternative Names: IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine;2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE;3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE;2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon. CAS No. 50847-11-5. Purity: 99+%. Product ID: ACM50847115. Molecular formula: C14H18N2O. Mole weight: 230.31. IUPAC Name: 2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one. Canonical SMILES: CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ibudilast | Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ibudilast | Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KC-404; AV-411; MN-166. CAS No. 50847-11-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0763. | |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Alternative Names: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grades: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31. | |
| Ibudilast impurity 1 | Ibudilast impurity 1. Uses: For analytical and research use. CAS No. 2713301-45-0. Molecular formula: C14H11D7N2O. Mole weight: 237.35. Catalog: APB2713301450. | |
| Ibudilast impurity 2 | Ibudilast impurity 2. Uses: For analytical and research use. CAS No. 101162-42-9. Molecular formula: C14H20N2O3. Mole weight: 264.33. Catalog: APB101162429. | |
| Ibudilast impurity 3 | Ibudilast impurity 3. Uses: For analytical and research use. Molecular formula: C14H13D7N2O3. Mole weight: 271.37. Catalog: APB12039. | |
| Ibudilast impurity 4 | Ibudilast impurity 4. Uses: For analytical and research use. CAS No. 102064-45-9. Molecular formula: C14H14D4N2O. Mole weight: 234.34. Catalog: APB102064459. | |
| Ibufenac | Ibufenac. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic acid; 4- (2-Methylpropyl) phenylacetic acid; 4-Isobutoxyphenylacetic acid. Grades: Highly Purified. CAS No. 1553-60-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H16O2. US Biological Life Sciences. | Worldwide |
| iBu-G-(S)-GNA phosphoramidite | Bz-G-(S)-GNA phosphoramidite: A Potent Anticancer and Antiviral Reagent for DNA Synthesis and Modification. This widely employed derivative is recognized for its high-purity and stability, enabling the synthesis of oligonucleotides with amplified efficacy and selectivity. Renowned for its use in drug discovery and development, the Bz-G-(S)-GNA nucleoside intermediate supports treatment of devastating conditions like HIV and cancer. Alternative Names: 2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxytriphenyl)methyl-N2-isobutyryl-(S)-9-(2,3-dihydroxypropyl)guanine; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]methyl]ethyl 2-cyanoethyl ester; (S)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (S)-GNA-G(iBu) phosphoramidite; DMT-G(iBu)-(S)-GNA Phosphoramidite. Grades: ≥98%. CAS No. 182625-68-9. Molecular formula: C44H52N7O7P. Mole weight: 797.88. | |
| Ibuprofen | Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Ibuprofen has been used to treat mild-moderate pain, fever, and inflammation. Alternative Names: α-methyl-4-(2-methylpropyl)-benzeneacetic acid. CAS No. 15687-27-1. Molecular formula: C13H18O2. Mole weight: 206.28. | |
| Ibuprofen | Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Ibuprofen. CAS No. 15687-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-78131. | |
| Ibuprofen | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-1g. Molecular Weight 206.28. See USA prepack pricing. | |
| Ibuprofen | 100g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-100g. Molecular Weight 206.28. See USA prepack pricing. | |
| Ibuprofen | Ibuprofen. Group: Biochemicals. Alternative Names: Isobutyl propanoicphenolic acid; (RS) -2- (4- (2-Methylpropyl) phenyl) propanoic acid; Racemic ibuprofen. Grades: Highly Purified. CAS No. 15687-27-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H18O2. US Biological Life Sciences. | Worldwide |
| Ibuprofen | 25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-25g. Molecular Weight 206.28. See USA prepack pricing. | |
| Ibuprofen (98%) | Ibuprofen (98%). CAS No. 15687-27-1. Purity: 99.70% (HPLC). Product ID: ALC-FP-15687271. Molecular formula: C13H18O2. Mole weight: 206.28 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ibuprofen acyl-β-D-glucuronide | Ibuprofen acyl-β-D-glucuronide (Ibuprofen glucuronide) is a selective TRPA1 antagonis. Ibuprofen acyl-β-D-glucuronide reduces AITC-evoked calcium response with an IC50 value of 60μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ibuprofen glucuronide. CAS No. 115075-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113018. | |
| Ibuprofen Acyl-beta-D-Glucuronide | Ibuprofen Acyl-beta-D-Glucuronide is an essential metabolite derived from ibuprofen, serving as a pivotal constituent in the synthesis of nonsteroidal anti-inflammatory drugs. Alternative Names: Ibuprofen glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-(4-Isobutylphenyl)Propanoyloxy]Tetrahydropyran-2-Carboxylic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-(4-Isobutylphenyl)-1-Oxopropoxy]-2-Tetrahydropyrancarboxylic Acid; Ibuprofen Acyl Glucuroni. Grades: > 95%. CAS No. 115075-59-7. Molecular formula: C19H26O8. Mole weight: 382.40. | |
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