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| Product | Description | |
|---|---|---|
| Ibrutinib-d4 | Ibrutinib-d4 is the labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective BrutonÂs tyrosine kinase (Btk) irreversible inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D4N6O2, Molecular Weight: 444.52. US Biological Life Sciences. |  Worldwide |
| Ibrutinib-[d5] | Ibrutinib-[d5] is the labelled analogue of Ibrutinib. Ibrutinib can be used to treat such cancers, including mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström macroglobulinemia. Synonyms: Ibrutinib D5. Grade: 98% by HPLC; 98% atom D. CAS No. 1553977-17-5. Molecular formula: C25H19D5N6O2. Mole weight: 445.53. |  |
| Ibrutinib dimer | Ibrutinib dimer is a Dimer of Ibrutinib. Ibrutinib dimer is an impurity of Ibrutinib[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2031255-23-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136113. |  |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Grade: 95%. CAS No. 2031255-23-7. Molecular formula: C50H48N12O4. Mole weight: 880.99. | |
| Ibrutinib, Free Base | Ibrutinib, also known as PCI-32765, is a selective and irreversible inhibitor of the enzyme Bruton's tyrosine kinase (BTK). It inhibited BTK potently, with an IC50 of 0.72 nM in enzymology assays and with an IC50 of 10 nM in cellular assay with Ramos cells. It demonstrated preference toward BTK over closely related kinases, blocked B cell function and BTK-dependent processes, and demonstrated clear efficacy in a mouse arthritis model. Young P.R., et al. "Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase." ChemMedChem. 2: 58-61 (2007). Group: Biochemicals. Alternative Names: 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one; Imbruvica. Grades: Purified. CAS No. 936563-96-1. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. Grade: > 95%. CAS No. 1022150-11-3. Molecular formula: C27H30N6O3. Mole weight: 486.58. | |
| Ibrutinib Impurity 18 | Ibrutinib Impurity 18. Uses: For analytical and research use. Alternative Names: (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 1022150-12-4. Molecular formula: C22H22N6O. Mole weight: 386.45. Catalog: APB1022150124. |  |
| Ibrutinib Impurity 2 | Ibrutinib Impurity 2. Grade: > 95%. Molecular formula: C28H26N6O3. Mole weight: 494.56. | |
| Ibrutinib impurity 20 | Ibrutinib impurity 20. Uses: For analytical and research use. CAS No. 1839090-60-6. Molecular formula: C25H24N6O4. Mole weight: 472.51. Catalog: APB1839090606. | |
| Ibrutinib impurity 21 | Ibrutinib impurity 21. Uses: For analytical and research use. Molecular formula: C25H23N5O3. Mole weight: 441.49. Catalog: APB11054. | |
| Ibrutinib impurity 22 | Ibrutinib impurity 22. Uses: For analytical and research use. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. Catalog: APB2031255260. | |
| Ibrutinib Impurity 23 | Ibrutinib Impurity 23. Uses: For analytical and research use. CAS No. 1838132-94-7. Molecular formula: C25H26N6O3. Mole weight: 458.52. Catalog: APB1838132947. | |
| Ibrutinib Impurity 24 | Ibrutinib Impurity 24. Uses: For analytical and research use. CAS No. 2437254-47-0. Molecular formula: C25H24N6O3. Mole weight: 456.51. Catalog: APB2437254470. | |
| Ibrutinib Impurity 31 | Ibrutinib Impurity 31. Uses: For analytical and research use. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)ethanone. CAS No. 1288338-95-3. Molecular formula: C24H24N6O2. Mole weight: 428.49. Catalog: APB1288338953. | |
| Ibrutinib Impurity 36 | Ibrutinib Impurity 36. Uses: For analytical and research use. Alternative Names: (R)-3-(1-(1-acryloylpiperidin-3-yl)-4-imino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)propanoic acid. Molecular formula: C28H28N6O4. Mole weight: 512.56. Catalog: APB02065. | |
| Ibrutinib Impurity 3-d5 | One of the isotopic labelled impurities of Ibrutinib, which has been found to be an irreversible inhibitor against Bruton's tyrosine kinase (Btk). Synonyms: 1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2,3-dihydroxy-1-propanone-d5. Molecular formula: C25H21N6O4D5. Mole weight: 479.55. | |
| Ibrutinib Impurity 4 | Ibrutinib Impurity 4. Grade: > 95%. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
| Ibrutinib Impurity 5 | Ibrutinib Impurity 5 is an impurity in commercial preparation of Ibrutinib. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. Grade: > 95%. Molecular formula: C25H25ClN6O2. Mole weight: 476.97. | |
| Ibrutinib Impurity 5 | Ibrutinib Impurity 5. Uses: For analytical and research use. Alternative Names: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-chloropropan-1-one. CAS No. 1288338-96-4. Molecular formula: C25H25ClN6O2. Mole weight: 476.96. Catalog: APB1288338964. | |
| Ibrutinib Impurity 6 | Ibrutinib Impurity 6. Synonyms: Ibrutinib impurity 6; 1987905-93-0; ZPJ4HT8UNA; UNII-ZPJ4HT8UNA; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one (Imatinib Impurity); 1-Propanone, 1,3-bis((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-; 1,3-bis[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]-1-[(3R)-3-[4-imino-3-(4-phenoxyphenyl)-1H,2H,4H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one; 1,3-bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidin-1-yl)propan-1-one; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one; 1,3-Bis((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one? (Imatinib Impurity; Ibrutinib Addition Adduct with (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl). Grade: > 95%. Molecular formula: C47H46N12O3. Mole weight: 826.97. | |
| Ibrutinib Impurity 8 | Ibrutinib Impurity 8 is a useful synthetic intermediate in the synthesis of Ibrutinib, a highly selective Bruton's tyrosine kinase (BTK) irreversible inhibitor. Synonyms: 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine; 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-; Ibrutinib intermeidate N-2. Grade: ≥97% by HPLC. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.33. | |
| Ibrutinib Impurity 8 | Ibrutinib Impurity 8. Uses: For analytical and research use. Alternative Names: 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine. CAS No. 330786-24-8. Molecular formula: C17H13N5O. Mole weight: 303.32. Catalog: APB330786248. | |
| Ibrutinib Impurity HNEJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grade: ≥95%. Molecular formula: C49H46N12O4. Mole weight: 866.99. | |
| Ibrutinib Impurity IMYBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grade: ≥95%. Molecular formula: C20H19N5O. Mole weight: 345.41. | |
| Ibrutinib Impurity JXBJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grade: ≥95%. Molecular formula: C26H26N6O2. Mole weight: 454.53. | |
| Ibrutinib Impurity MDDYH | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grade: ≥95%. CAS No. 2052279-49-7. Molecular formula: C25H24N6O3. Mole weight: 456.51. | |
| Ibrutinib Impurity SMSJ | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Grade: ≥95%. Molecular formula: C32H24N8O2. Mole weight: 552.60. | |
| Ibrutinib Methoxy Impurity | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-methoxypropan-1-one; Ibrutinib impurity JYD. Grade: ≥95%. CAS No. 2031255-26-0. Molecular formula: C26H28N6O3. Mole weight: 472.55. | |
| Ibrutinib-MPEA | Ibrutinib-MPEA is an orally active, blood-brain barrier permeable inhibitor of BTK and STAT5. As a derivative of Ibrutinib (HY-10997) conjugated with a PROTAC linker, Ibrutinib-MPEA allows the synthesis of a series of PROTAC molecules. Ibrutinib-MPEA significantly reduces the proliferation of neoplastic mast cells and primary mastocytoma cells by inducing apoptosis and inhibiting IgE-dependent histamine release. Ibrutinib-MPEA is applicable to the research of canine mast cell tumors, cerebral ischemia/reperfusion injury in diabetic mice, and neuroinflammation-related diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1710768-30-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-43521. | |
| Ibrutinib (PCI-32765) | Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I. Group: Inhibitors. Alternative Names: PCI-32765. CAS No. 936563-96-1. Pack Sizes: 5mg. Product ID: S2680. Formula: C25H24N6O2. Smiles: C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Ibrutinib (Standard) | Ibrutinib (Standard) is the analytical standard of Ibrutinib. This product is intended for research and analytical applications. Ibrutinib (PCI-32765) is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PCI-32765 (Standard). CAS No. 936563-96-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10997R. | |
| IBS008738 | IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 385425-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112821. | |
| IBT6A | IBT6A is an impurity of Ibrutinib. IBT6A can be used in synthesis of IBT6A Ibrutinib dimer and IBT6A adduct[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1022150-12-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-13036A. | |
| Ibudilast | Ibudilast. Alternative Names: IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine;2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE;3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE;2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon. CAS No. 50847-11-5. Purity: 99+%. Product ID: ACM50847115. Molecular formula: C14H18N2O. Mole weight: 230.31. IUPAC Name: 2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one. Canonical SMILES: CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Synonyms: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grade: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31. | |
| Ibudilast | Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ibudilast | Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KC-404; AV-411; MN-166. CAS No. 50847-11-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0763. | |
| Ibudilast-d3 (Major) | Labeled Ibudilast. A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). Group: Biochemicals. Alternative Names: 2-Methyl-1-[2- (1-methylethyl) pyrazolo[1, 5-a]pyridin-3-yl]-1-propanone-d3; 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3; 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3; AV 411-d3; KC 404-d3; Ketas-d3. Grades: Highly Purified. CAS No. 102064-45-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ibudilast-[d7] | Ibudilast-[d7] is a labelled analogue of Ibudilast. Ibudilast is a phosphodiesterase inhibitor with anti-inflammatory, vasodilator and neuroprotective properties. It can be used in the treatment of asthma, stroke and multiple sclerosis. Synonyms: Ibudilast D7. Grade: 95% by HPLC; 95% atom D. CAS No. 1204192-90-4. Molecular formula: C14H11D7N2O. Mole weight: 237.35. | |
| Ibudilast impurity 1 | Ibudilast impurity 1. Uses: For analytical and research use. CAS No. 2713301-45-0. Molecular formula: C14H11D7N2O. Mole weight: 237.35. Catalog: APB2713301450. | |
| Ibudilast impurity 2 | Ibudilast impurity 2. Uses: For analytical and research use. CAS No. 101162-42-9. Molecular formula: C14H20N2O3. Mole weight: 264.33. Catalog: APB101162429. | |
| Ibudilast impurity 3 | Ibudilast impurity 3. Uses: For analytical and research use. Molecular formula: C14H13D7N2O3. Mole weight: 271.37. Catalog: APB12039. | |
| Ibudilast impurity 4 | Ibudilast impurity 4. Uses: For analytical and research use. CAS No. 102064-45-9. Molecular formula: C14H14D4N2O. Mole weight: 234.34. Catalog: APB102064459. | |
| Ibufenac | Ibufenac. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic acid; 4- (2-Methylpropyl) phenylacetic acid; 4-Isobutoxyphenylacetic acid. Grades: Highly Purified. CAS No. 1553-60-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H16O2. US Biological Life Sciences. | Worldwide |
| Ibufenac | Ibufenac is an analog of ibuprofen, and also acts as a COX inhibitor. Ibufenac can be used as an analgesic and anti-inflammatory agent but exhibits hepatotoxicity. Synonyms: Dytransin; Ibunac; 4-Isobutylphenylacetic acid; 2-[4-(2-methylpropyl)phenyl]acetic acid; NSC 99976. Grade: ≥95%. CAS No. 1553-60-2. Molecular formula: C12H16O2. Mole weight: 192.3. | |
| Ibufenac (4- (2-Methylpropyl) benzeneacetic Acid, Dytransin, Ibunac) | Used as an analgesic, anti-inflammatory. Group: Biochemicals. Alternative Names: 4- (2-Methylpropyl) benzeneacetic Acid, Dytransin, Ibunac. Grades: Highly Purified. Pack Sizes: 5mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| iBu-G-(S)-GNA phosphoramidite | Bz-G-(S)-GNA phosphoramidite: A Potent Anticancer and Antiviral Reagent for DNA Synthesis and Modification. This widely employed derivative is recognized for its high-purity and stability, enabling the synthesis of oligonucleotides with amplified efficacy and selectivity. Renowned for its use in drug discovery and development, the Bz-G-(S)-GNA nucleoside intermediate supports treatment of devastating conditions like HIV and cancer. Synonyms: 2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxytriphenyl)methyl-N2-isobutyryl-(S)-9-(2,3-dihydroxypropyl)guanine; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]methyl]ethyl 2-cyanoethyl ester; (S)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (S)-GNA-G(iBu) phosphoramidite; DMT-G(iBu)-(S)-GNA Phosphoramidite. Grade: ≥98%. CAS No. 182625-68-9. Molecular formula: C44H52N7O7P. Mole weight: 797.88. | |
| Ibulocydine | Ibulocydine is a potent CDK inhibitor. Ibulocydine has high activity against Cdk7/cyclin H/Mat1 and Cdk9/cyclin T. Ibulocydine inhibited the growth of HCC cells more effectively than other Cdk inhibitors, including olomoucine and roscovitine, whereas ibulocydine as well as the other Cdk inhibitors and BMK-Y101 minimally influenced the growth of normal hepatocyte cells. Ibulocydine induced apoptosis in HCC cells, most likely by inhibiting Cdk7 and Cdk9. In vitro treatment of HCC cells with ibulocydine rapidly blocked phosphorylation of the carboxyl-terminal domain (CTD) of the large subunit of RNA polymerase II, a process mediated by Cdk7/9. Anti-apoptotic gene products such as Mcl-1, survivin, and X-linked IAP (XIAP) are crucial for the survival of many cell types, including HCC. Following the inhibition of RNA polymerase II phosphorylation, ibulocydine caused rapid down-regulation of Mcl-1, survivin, and XIAP, thus inducing apoptosis. Furthermore, ibulocydine effectively induced apoptosis in HCC xenografts with no toxic side effects. These results suggest that ibulocydine is a strong candidate anti-cancer drug for the treatment of HCC. Synonyms: Ibulocydine. Grade: 98%. CAS No. 1314096-68-8. Molecular formula: C16H20BrN5O6. Mole weight: 458.26. | |
| Ibuprofen | Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Ibuprofen has been used to treat mild-moderate pain, fever, and inflammation. Synonyms: α-methyl-4-(2-methylpropyl)?-benzeneacetic acid. CAS No. 15687-27-1. Molecular formula: C13H18O2. Mole weight: 206.28. | |
| Ibuprofen | 100g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-100g. Molecular Weight 206.28. See USA prepack pricing. |  |
| Ibuprofen | 25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-25g. Molecular Weight 206.28. See USA prepack pricing. | |
| Ibuprofen | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H18O2. CAS No. 15687-27-1. Prepack ID 90019028-1g. Molecular Weight 206.28. See USA prepack pricing. | |
| Ibuprofen | Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][5][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Ibuprofen. CAS No. 15687-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-78131. | |
| Ibuprofen | Ibuprofen. Group: Biochemicals. Alternative Names: Isobutyl propanoicphenolic acid; (RS) -2- (4- (2-Methylpropyl) phenyl) propanoic acid; Racemic ibuprofen. Grades: Highly Purified. CAS No. 15687-27-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H18O2. US Biological Life Sciences. | Worldwide |
| Ibuprofen-[13C,d3] | Ibuprofen-[13C,d3] is the labelled analogue of Ibuprofen, which is a nonsteroidal anti-inflammatory drug. Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Synonyms: Ibuprofen 13C D3; α-Methyl-13C,d3-4-(isobutyl)phenylacetic Acid; [13C,2H3]-Ibuprofen. Grade: 95% by HPLC; 95% atom 13C; 95% atom D. CAS No. 1261394-40-4. Molecular formula: C12[13C]H15D3O2. Mole weight: 210.29. | |
| Ibuprofen (98%) | Ibuprofen (98%). CAS No. 15687-27-1. Purity: 99.70% (HPLC). Product ID: ALC-FP-15687271. Molecular formula: C13H18O2. Mole weight: 206.28 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ibuprofen acyl-β-D-glucuronide | Ibuprofen acyl-β-D-glucuronide (Ibuprofen glucuronide) is a selective TRPA1 antagonis. Ibuprofen acyl-β-D-glucuronide reduces AITC-evoked calcium response with an IC50 value of 60μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ibuprofen glucuronide. CAS No. 115075-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113018. | |
| Ibuprofen Acyl-beta-D-Glucuronide | Ibuprofen Acyl-beta-D-Glucuronide is an essential metabolite derived from ibuprofen, serving as a pivotal constituent in the synthesis of nonsteroidal anti-inflammatory drugs. Synonyms: Ibuprofen glucuronide; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-(4-Isobutylphenyl)Propanoyloxy]Tetrahydropyran-2-Carboxylic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[2-(4-Isobutylphenyl)-1-Oxopropoxy]-2-Tetrahydropyrancarboxylic Acid; Ibuprofen Acyl Glucuroni. Grade: > 95%. CAS No. 115075-59-7. Molecular formula: C19H26O8. Mole weight: 382.40. | |
| Ibuprofen alcohol | Ibuprofen alcohol. Group: Biochemicals. Alternative Names: b-Methyl-4- (2-methylpropyl) benzeneethanol; 2- (4-Isobutylphenyl) propanol; 2-(4-Isobutylphenyl)propyl alcohol. Grades: Highly Purified. CAS No. 36039-36-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences. | Worldwide |
| Ibuprofen Amide Impurity | Ibuprofen Amide Impurity. Grade: > 95%. Molecular formula: C22H29NO2. Mole weight: 339.48. | |
| Ibuprofen Carboxylic Acid | Ibuprofen Carboxylic Acid is the major metabolite of Ibuprofen which may reduce the risk of cataracts by protecting lenticular enzymes. Synonyms: 4-(1-Carboxyethyl)-α-methyl-benzenepropanoic Acid; 2,4'-(2-Carboxypropyl)phenylpropionic Acid; Carboxyibuprofen; 3-[4-(1-Carboxyethyl)phenyl]-2-methylpropionic acid. Grade: > 95%. CAS No. 15935-54-3. Molecular formula: C13H16O4. Mole weight: 236.27. | |
| Ibuprofen Carboxylic Acid-d3 (Mixture of Diastereomers) | The major labeled metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-α-methylbenzenepropanoic Acid-d3; 2, 4- (2-Carboxypropyl) phenylpropionic Acid-d3; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid-d3; Carboxyibuprofen-d3. Grades: Highly Purified. CAS No. 1216505-29-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ibuprofen Carboxylic Acid (Mixture of Diastereomers) (4-(1-Carboxyethyl)-µ-methyl-benzenepropanoic Acid, 2, 4- (2-Carboxypropyl) phenylpropionic Acid, 2-[4- (2-Carboxypropyl) phenyl]propionic Acid, Carboxyibuprofen) | The major metabolite of Ibuprofen; may reduce the risk of cataract by protecting lenticular enzymes. Group: Biochemicals. Alternative Names: 4-(1-Carboxyethyl)-a-methyl-benzenepropanoic Acid; 2, 4- (2-Carboxypropyl) phenylpropionic Acid; 2-[4- (2-Carboxypropyl) phenyl]propionic Acid; Carboxyibuprofen. Grades: Highly Purified. CAS No. 15935-54-3. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Ibuprofen-d3 | Ibuprofen-d3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor with IC50s of 13 μM and 370 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Ibuprofen-d3. CAS No. 121662-14-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-78131S. | |
| Ibuprofen-[d3] | Ibuprofen-[d3] is the labelled analogue of Ibuprofen, which is a selective cyclooxygenase inhibitor. Synonyms: Ibuprofen-D3; rac Ibuprofen-d3; 2-(4-Isobutylphenyl)propionic Acid-d3; Brufen-d3; Motrin-d3; Advil-d3; Nurofen-d3; Dolgit-d3; (+/-)-Ibuprofen D3. Grade: ≥97%; ≥99% atom D. CAS No. 121662-14-4. Molecular formula: C13H15D3O2. Mole weight: 209.30. | |
| Ibuprofen Degradation Impurity I | Ibuprofen Degradation Impurity I. Uses: For analytical and research use. Molecular formula: C22H30ClNO3. Mole weight: 391.94. Catalog: APB08132. | |
| Ibuprofen Degradation Impurity II | Ibuprofen Degradation Impurity II. Uses: For analytical and research use. Molecular formula: C22H30ClNO3. Mole weight: 391.94. Catalog: APB08133. | |
| Ibuprofen Degradation Impurity III | Ibuprofen Degradation Impurity III. Uses: For analytical and research use. Molecular formula: C22H30ClNO3. Mole weight: 391.94. Catalog: APB08134. | |
| Ibuprofen EP Impurity A | Ibuprofen EP Impurity A. Uses: For analytical and research use. CAS No. 66622-47-7. Molecular formula: C13H18O2. Mole weight: 206.29. Catalog: APB66622477. | |
| Ibuprofen EP Impurity A | Ibuprofen EP Impurity A is an Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Synonyms: m-Isobutyl Ibuprofen; (2RS)-2-[3-(2-Methylpropyl)phenyl] propanoic acid; 2-(3-isobutylphenyl)propanoic acid; α-Methyl-3-(2-methylpropyl)benzeneacetic Acid,α-(3-Isobutylphenyl)propionic Acid. Grade: > 95%. CAS No. 66622-47-7. Molecular formula: C13H18O2. Mole weight: 206.29. | |
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