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Itraconazole Impurity 20. Uses: For analytical and research use. CAS No. 89848-13-5. Molecular formula: C30H32Cl2N8O4. Mole weight: 639.53. Catalog: APB89848135.
Itraconazole Impurity 21
Itraconazole Impurity 21. Uses: For analytical and research use. CAS No. 89848-20-4. Molecular formula: C22H27N5O2. Mole weight: 393.49. Catalog: APB89848204.
Itraconazole Impurity 22
Itraconazole Impurity 22. Uses: For analytical and research use. Alternative Names: N-(4-(((2R,4S)-2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-N-(2-((4-(1-(sec-butyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)amino)ethyl)formamide. Molecular formula: C34H36Cl2N8O5. Mole weight: 707.61. Catalog: APB02067.
Itraconazole Impurity 22
Itraconazole Impurity 22. Uses: For analytical and research use. CAS No. 106461-41-0. Molecular formula: C22H27N5O2. Mole weight: 393.49. Catalog: APB106461410.
Itraconazole Impurity 23
Itraconazole Impurity 23. Uses: For analytical and research use. CAS No. 103661-14-9. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.25. Catalog: APB103661149.
Itraconazole Impurity 24
Itraconazole Impurity 24. Uses: For analytical and research use. CAS No. 79538-91-3. Molecular formula: C21H25N5O2. Mole weight: 379.46. Catalog: APB79538913.
Itraconazole Impurity 25
Itraconazole Impurity 25. Uses: For analytical and research use. CAS No. 74852-62-3. Molecular formula: C17H21N3O. Mole weight: 283.38. Catalog: APB74852623.
Itraconazole Impurity 26
Itraconazole Impurity 26. Uses: For analytical and research use. CAS No. 89848-15-7. Molecular formula: C23H29N5O2. Mole weight: 407.52. Catalog: APB89848157.
Itraconazole Impurity 27
Itraconazole Impurity 27. Uses: For analytical and research use. CAS No. 1437468-92-2. Molecular formula: C29H28Cl2N6O5. Mole weight: 611.48. Catalog: APB1437468922.
Itraconazole Impurity 28
Itraconazole Impurity 28. Uses: For analytical and research use. CAS No. 207970-87-4. Molecular formula: C35H38Cl2N8O5. Mole weight: 721.64. Catalog: APB207970874.
Itraconazole Impurity 29
Itraconazole Impurity 29. Uses: For analytical and research use. CAS No. 1217516-26-1. Molecular formula: C35H30Cl2D8N8O5. Mole weight: 729.69. Catalog: APB1217516261.
Itraconazole Impurity 30
Itraconazole Impurity 30. Uses: For analytical and research use. CAS No. 67914-85-6. Molecular formula: C13H13Cl2N3O3. Mole weight: 330.17. Catalog: APB67914856.
Itraconazole Impurity 31
Itraconazole Impurity 31. Uses: For analytical and research use. Molecular formula: C35H36Cl2N8O6. Mole weight: 735.62. Catalog: APB08129.
Itraconazole Impurity 32
Itraconazole Impurity 32. Uses: For analytical and research use. CAS No. 1199350-02-1. Molecular formula: C35H36Cl2N8O6. Mole weight: 735.62. Catalog: APB1199350021.
Itraconazole Impurity 8
Itraconazole Impurity 8. Uses: For analytical and research use. CAS No. 115897-54-6. Molecular formula: C14H15Cl2N3O5S. Mole weight: 408.25. Catalog: APB115897546.
Itraconazole Impurity 9
Itraconazole Impurity 9. Uses: For analytical and research use. CAS No. 112560-33-5. Molecular formula: C35H36Cl2N8O5. Mole weight: 719.62. Catalog: APB112560335.
Itraconazole (Oriconazole, Sporanox, Triasporin)
An orally active antimycotic structurally related to Ketoconazole. Group: Biochemicals. Alternative Names: Oriconazole, Sporanox, Triasporin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Itraconazole solution
Itraconazole solution. Uses: For analytical and research use. CAS No. 84625-61-6. Mole weight: 705.63. Catalog: AP84625616-A.
ITSA-1
ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA)-induced cell cycle arrest, histone acetylation, and transcriptional activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 200626-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100508.
Cell-permeable. ITSA-1 is a suppressor of Trichostatin A (TSA) and a molecular tool for dissecting gene regulation by distinct acetylation events (histone and tubulin). ITSA-1 specifically suppresses TSA inhibition of HDAC (histone deacetylase), but not other HDAC inhibitors. ITSA-1 reverses TSA induced histone acetylation, overall deacetylation. ITSA-1 also reverses TSA induced cell cycle arrest and apoptosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 200626-61-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ITX3
ITX3 is a specific and nontoxic inhibitor of TrioN (N-terminal GEF domain of the multidomain Trio protein) with an IC50 value of 76 μM. ITX3 can be used for the research of agent[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 347323-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16663.
ITX 3
ITX 3. Group: Biochemicals. Grades: Purified. CAS No. 347323-96-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ITX5061
ITX5061 is an orally active type II non-competitive p38 MAPK inhibitor. ITX5061 increases HDL-C levels by inhibiting SR-BI activity. ITX5061 also moderately elevates ApoA-I levels. ITX5061 reduces early atherosclerotic lesions in the aortic arch of mice fed an atherogenic diet. ITX5061 can be used in the research of atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1252679-52-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19900.
IU1
IU1. Group: Biochemicals. Grades: Purified. CAS No. 314245-33-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IU1
IU1 is a selective, reversible USP14 inhibitor with an IC50 of 4-5 μM. IU1 binds USP14s catalytic cleft to block deubiquitinase activity. IU1 induces calpain-dependent Tau cleavage, causes ATP deficits, reduces E1~Ub thioester levels and 26S proteasome assembly. IU1 enhances 26S proteasome chymotrypsin-like activity, modulates LC3B-dependent autophagy flux, reduces cancer cell proliferation and migration, and blocks G0/G1 to S phase cell cycle transition in follicular thyroid cancer cells. IU1 activates autophagy-lysosomal and ubiquitin-proteasome pathways, triggers apoptosis, and reduces cervical cancer cell growth. IU1 enhances degradation of proteasome substrates linked to neurodegenerative disease, accelerates oxidized protein degradation, and increases oxidative stress resistance. IU1 can be used for the research of Alzheimers disease, follicular thyroid cancer, ischemic stroke, cervical cancer, and neurodegenerative disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13817.
IU1-248
IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2307472-03-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122885.
IU1-47
IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 μM. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 μM. IU1-47 induces tau elimination in cultured neurons[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 670270-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122243.
Ivabradine-[d3]
Ivabradine-[d3] is the labelled analogue of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Synonyms: Ivabradine D3; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d3 Hydrochloride; Corlentor-d3; Procoralan-d3; Ivabradine-d3. Grade: >95%. CAS No. 1217977-70-2. Molecular formula: C27H33D3N2O5. Mole weight: 471.60.
Ivabradine-d3 hydrochloride
Ivabradine-d3 hydrochloride. Alternative Names: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. CAS No. 1217809-61-4. Product ID: ACM1217809614. Molecular formula: C27H34D3ClN2O5. Mole weight: 508.06. Alfa Chemistry - ISO 9001:32057 Certified.
Ivabradine-[d3] Hydrochloride
Ivabradine-[d3] Hydrochloride is the labelled salt of Ivabradine. Ivabradine is an inhibitor of the sinoatrial node channel and can be used to treat chronic stable angina patients with normal sinus rhythm. Uses: The hydrochloride salt form of isotope labelled ivabradine. Synonyms: Ivabradine-D3 Hydrochloride; Ivabradin D3 HCl; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino-d3]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3 Hydrochloride; Procoralan-d3 Hydrochloride. Grade: >95%. CAS No. 1217809-61-4. Molecular formula: C27H34D3ClN2O5. Mole weight: 508.06.
Ivabradine-d3 Hydrochloride
Labeled Ivabradine. Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3-[3-[[[(7S)-3, 4-Dimethoxybicyclo[4. 2. 0]octa-1, 3, 5-trien-7-yl]methyl]methylamino-d3]propyl]-1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor-d3; Procoralan-d3; S-16257-d3. Grades: Highly Purified. CAS No. 1217809-61-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivabradine-[d6] hydrochloride
Ivabradine-[d6] hydrochloride is the labelled analogue of Ivabradine Hydrochloride. Ivabradine hydrochloride has been used as a potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel (HCN)2 blocker in embryoid body (EB) and rat engineered heart tissue (EHT). Synonyms: Ivabradine D6 hydrochloride; 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one-d6 hydrochloride; Corlentor-d6; Procoralan-d6. Grade: 98% by CP. CAS No. 2070009-63-9. Molecular formula: C27H30D6N2O5.HCl. Mole weight: 511.08.
Ivabradine-d6 hydrochloride
Ivabradine-d6 hydrochloride is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent. Uses: Scientific research. Category: Signaling pathways. CAS No. 2070009-63-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0162AS.
Ivabradine hydrochloride
Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grade: >98%. CAS No. 148849-67-6. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05.
Ivabradine hydrochloride
Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 148849-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0162A.
Ivabradine hydrochloride
Ivabradine hydrochloride. Alternative Names: Ivabradine HCl;Ivabradine hydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride;Corlentor;Procoralan;S-16257;(7,8-Dimethoxy 3-(3-(((1S)-(4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one hydrochloride. CAS No. 148849-67-6. Product ID: ACM148849676. Molecular formula: C27H36N2O5.HCl. Mole weight: 505.05. Alfa Chemistry - ISO 9001:32057 Certified.
Ivabradine hydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-1g. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine hydrochloride
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H36N2O5 · HCl. CAS No. 148849-67-6. Prepack ID 58443475-100mg. Molecular Weight 505.05. See USA prepack pricing.
Ivabradine Hydrochloride
Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. Group: Biochemicals. Alternative Names: 3- [3- [ [ [ (7S) -3, 4-Dimethoxybicyclo [4. 2. 0] octa-1, 3, 5-trien-7-yl] methyl] methylamino] propyl] -1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257. Grades: Highly Purified. CAS No. 148849-67-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ivabradine Impurity 10 (free base)
Ivabradine Impurity 10 (free base). Uses: For analytical and research use. Alternative Names: (S)-2-(2-(2-((3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic acid. CAS No. 1462470-54-7. Molecular formula: C27H38N2O6. Mole weight: 486.6. Catalog: APB1462470547.
Ivabradine Impurity 15
Ivabradine Impurity 15. Uses: For analytical and research use. Alternative Names: (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl) -7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione hydrochloride. CAS No. 1616710-50-9. Molecular formula: C27H34N2O6·HCl. Mole weight: 519.03. Catalog: APB1616710509.
Ivabradine Impurity 32
Ivabradine Impurity 32. Uses: For analytical and research use. Alternative Names: (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7-hydroxy-8-methoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one. CAS No. 304462-60-0. Molecular formula: C26H34N2O5. Mole weight: 454.56. Catalog: APB304462600.
Ivacaftor
Ivacaftor. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide; Ivacaftor; Kalydeco; VX 770. Grades: Highly Purified. CAS No. 873054-44-5. Pack Sizes: 5mg. Molecular Formula: C24H28N2O3, Molecular Weight: 392.49. US Biological Life Sciences.
Worldwide
Ivacaftor
Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13017.
Ivacaftor-d18
Ivacaftor-d18. Group: Biochemicals. Alternative Names: N-[2,4-Bis[1,1-di(methyl-d3)ethyl-2,2,2-d3]-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide-d18. Grades: Highly Purified. CAS No. 1413431-05-6. Pack Sizes: 2.5mg. Molecular Formula: C24H10D18N2O3, Molecular Weight: 410.6. US Biological Life Sciences.
Worldwide
Ivacaftor-[d18]
Ivacaftor-[d18] is the labelled analogue of Ivacaftor. Ivacaftor is an orally bioavailable potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) that improves chloride transport. Synonyms: Ivacaftor D18. Grade: 95% by HPLC; 95% atom D. CAS No. 1413431-05-6. Molecular formula: C24H10D18N2O3. Mole weight: 410.6.
Ivacaftor-d9
Ivacaftor-d9 is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-770-d9. CAS No. 1413431-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-13017S.
Ivacaftor impurities8 (Kynurenic Acid Impurity 4)
Ivacaftor impurities8 (Kynurenic Acid Impurity 4). Uses: For analytical and research use. CAS No. 34785-11-0. Molecular formula: C10H7NO3. Mole weight: 189.17. Catalog: APB34785110.
Ivacaftor N-Glucuronide
Ivacaftor N-Glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C30H36N2O9, Molecular Weight: 568.61. US Biological Life Sciences.
Worldwide
Ivacaftor (VX-770)
Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively. Group: Inhibitors. Alternative Names: VX-770. CAS No. 873054-44-5. Pack Sizes: 5mg. Product ID: S1144. Formula: C24H28N2O3. Smiles: CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Ivachtin
Ivachtin (Caspase-3 Inhibitor VII; compound 7a) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor with an IC50 of 23 nM. Ivachtin has modest selectivity for the remaining caspases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Caspase-3 Inhibitor VII. CAS No. 745046-84-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1095.
Ivaltinostat formic
Ivaltinostat (CG-200745) formic is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat formic inhibits deacetylation of histone H3 and tubulin. Ivaltinostat formic induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat formic enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU; HY-90006). Ivaltinostat formic induces apoptosis and has anti-tumour effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CG-200745 formic. CAS No. 3078712-42-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16138A.
Ivebradine impurity 1. Uses: For analytical and research use. Molecular formula: C27H36N2O6. Mole weight: 484.59. Catalog: APB11271.
Ivebradine impurity 3
Ivebradine impurity 3. Uses: For analytical and research use. CAS No. 866783-13-3. Molecular formula: C12H18ClNO2. Mole weight: 243.73. Catalog: APB866783133.
Ivebradine impurity 4
Ivebradine impurity 4. Uses: For analytical and research use. Molecular formula: C28H38ClNO5. Mole weight: 504.06. Catalog: APB11272.
Ivebradine impurity 5
Ivebradine impurity 5. Uses: For analytical and research use. CAS No. 2253977-80-7. Molecular formula: C27H36N2O6. Mole weight: 484.59. Catalog: APB2253977807.
Ivebradine impurity 6
Ivebradine impurity 6. Uses: For analytical and research use. CAS No. 1086026-31-4. Molecular formula: C27H34N2O5. Mole weight: 466.58. Catalog: APB1086026314.
Ivebradine impurity 7
Ivebradine impurity 7. Uses: For analytical and research use. Molecular formula: C27H34N2O6. Mole weight: 482.58. Catalog: APB11273.
Ivermectin
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import[1][2][3][4]. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-933; CD-5024; K-237. CAS No. 70288-86-7. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-15310.
Ivermectin
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H74O14. CAS No. 70288-86-7. Prepack ID 21022571-1g. Molecular Weight 875.09. See USA prepack pricing.
Ivermectin
Ivermectin. CAS No. 70288-86-7. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Ivermectin
Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1; 22,23-Dihydro C-076B1; Heartgard 30; Ivomec; Ivosint; Mectizan; Stromectol; Uvemec; Vermic; Zimecterin. Grades: Highly Purified. CAS No. 70288-86-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences.
Worldwide
Ivermectin
Ivermectin is a glutamate-gated chloride channel (GluCls) activator, which is used as an antiparasitic drug for the treatment of certain parasitic roundworm infections. Ivermectin inhibits the chloride channels of helminthic parasites and has been shown to have clinical efficacy for the treatment of onchocerciasis, strongyloidiasis, and ectoparasitic infection. Ivermectin is a mixture of mostly Ivermectin B1a (>80%) with some Ivermectin B1b (<20%), which are macrolides from Streptomyces avermitilis. Uses: Antiparasitic agents. Synonyms: Ivermectin B1a and Ivermectin B1b (Mixture); Avermectin H2B1a and Avermectin H2B1b (Mixture); Dihydroavermectin B1a and Dihydroavermectin B1b (Mixture); 22,23-Dihydroavermectin B1a and 22,23-Dihydroavermectin B1b (Mixture). Grade: ≥95%. CAS No. 70288-86-7. Molecular formula: C48H74O14.C47H72O14. Mole weight: 1736.16.
Ivermectin aglycone is a semi-synthetic produced by the hydrolysis of the disaccharide unit of ivermectin. Ivermectin aglycone is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 aglycone,Ivermectin B1 aglycone. Grades: Highly Purified. CAS No. 123997-59-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ivermectin B1a
Ivermectin B1a is a major component of Ivermectin, a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19. Group: Biochemicals. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a; 2,23-Dihydroavermectin B1a; Dihydroavermectin B1a. Grades: Highly Purified. CAS No. 71827-03-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??O??, Molecular Weight: 875.09. US Biological Life Sciences.
Worldwide
Ivermectin B1a
Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310)[1]. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71827-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-126937.
Ivermectin B1a
It is the major component (>80%) of the commercial anthelmintic, ivermectin. It exerts its anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. It is also a potent insecticide. Synonyms: Ivermectin; Dihydroavermectin B1a; 22,23-Dihydroavermectin B1a; Ivermectin Component B1a; avermectin H2B1a; 5-O-demethyl-22,23-dihydroavermectin A1a; MK-933; Avermectin A1a, 5-O-demethyl-22,23-dihydro-; 22,23-Dihydroavermectin B(1)a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin A1a deriv.; Ivermectin (IVM); IVM; dihydro avermectin Bla; H2B1a; Ivermectin (MK-0933). Grade: >95% by HPLC. CAS No. 71827-03-7. Molecular formula: C48H74O14. Mole weight: 875.09.
Ivermectin B1a-[d2]
Ivermectin B1a-[d2] is the labelled analogue of Ivermectin B1a, which is a major component of ivermectin and a semi-synthetic derivative of abamectin. It is a mixture including not less than 80% component B1a and not more than 20% component B1b. It is used as an antihelmintic. Synonyms: Ivermectin B1a-d2; 5-O-Demethyl-22,23-dihydro-avermectin A1a-d2; 2,23-Dihydroavermectin B1a-d2; Dihydroavermectin B1a-d2. Grade: ≥94%; ≥95% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11.