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| Product | Description | |
|---|---|---|
| IWP-4 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| IWP L6 | IWP L6. Group: Biochemicals. Grades: Purified. CAS No. 1427782-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| IWP L6 | IWP L6 (Porcn Inhibitor III) is a Porcn inhibitor with an EC 50 of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Porcn Inhibitor III. CAS No. 1427782-89-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15825. |  |
| IWP-O1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IWR-1 | IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway. Uses: Scientific research. Group: Signaling pathways. Alternative Names: endo-IWR 1; IWR-1-endo. CAS No. 1127442-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12238. | |
| IWR-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| IWR-1 | IWR-1. CAS No: 430429-02-0 |  Sarchem Laboratories New Jersey NJ |
| IWR-1 (IWR-1-endo) | Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3 β. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3 β. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay). Group: Biochemicals. Alternative Names: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-82-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 409.4. US Biological Life Sciences. | Worldwide |
| IXA4 | IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1185329-96-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139214. | |
| IXA4 | IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 transiently activates protective IRE1/XBP1s signaling in liver without inducing RIDD or TRAF2/JNK signaling. IXA4 treatment improves systemic glucose metabolism and liver insulin action through IRE1-dependent remodeling of the hepatic transcriptome that reduces glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Our findings indicate that systemic, transient activation of IRE1/XBP1s signaling engenders multi-tissue benefits that integrate to mitigate obesity-driven metabolic dysfunction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXA4; IXA-4; IXA 4. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1185329-96-7. Molecular formula: C24H28N4O4. Mole weight: 436.51. Purity: >98%. IUPACName: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide. Canonical SMILES: CC1=CC=C(OCCN(C(CN2N=CC(NC(=O)CCOC3=CC=CC=C3)=C2)=O)C)C=C1. Product ID: ACM1185329967. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ixazomib. |  |
| IXA6 | IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021106-40-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139212. | |
| Ixabepilone | Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IXABEPILONE;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-1,5,7,9,9-pentamethyl-14-[(E) -1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-13-azabicyclo[14. 1.0]heptadecane-8,12-dione;Aza-epothilone B;Bms 247550-1;Ixempra;Ixempra kit;Unii-K27005np0a;Azi-epothilone B. Product Category: Inhibitors. Appearance: Solid. CAS No. 219989-84-1. Molecular formula: C27H42N2O5S. Mole weight: 506.7. Purity: 0.9984. Canonical SMILES: O=C([C@@H]([C@H]([C@H](CCC[C@]1(O[C@]1(C[C@H](N2)/C(C)=C/C3=CSC(C)=N3)[H])C)C)O)C)C(C)([C@H](CC2=O)O)C. Product ID: ACM219989841. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ixabepilone | Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arrests cells in the G2-M phase of the cell cycle and induces tumor cell apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-247550; Aza-epothilone B. CAS No. 219989-84-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10222. | |
| Ixazomib | Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC 50 of 3.4 nM ( K i of 0.93 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN2238. CAS No. 1072833-77-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10453. | |
| Ixazomib citrate | Ixazomib citrate (MLN9708) is a selective, orally active, second-generation proteasome inhibitor. Ixazomib citrate can be used for the study of a broad range of human malignancies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN9708. CAS No. 1239908-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10452. | |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Synonyms: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. Grade: 98%. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. |  |
| Ixazomib Impurity 15 | Ixazomib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10203-08-4. Molecular formula: C7H4Cl2O. Mole weight: 175.01. Catalog: APB10203084. | |
| Ixazomib Impurity 19 | Ixazomib Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1239908-20-3. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. Catalog: APB1239908203. | |
| Ixazomib Impurity 22 | Ixazomib Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10541-71-6. Molecular formula: C7H3Cl5. Mole weight: 264.35. Catalog: APB10541716. | |
| Ixazomib Impurity 9 | Ixazomib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.35. Catalog: APB1092351671. | |
| Ixekizumab | Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A ( K D <3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY2439821. CAS No. 1143503-69-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9924. | |
| Ixosin | Ixosin is an antibacterial peptide isolated from Ixodes sinensis (Hard tick). It has activity against gram-negative bacteria and fungi. Synonyms: Gly-Leu-His-Lys-Val-Met-Arg-Glu-Val-Leu-Gly-Tyr-Glu-Arg-Asn-Ser-Tyr-Lys-Lys-Phe-Phe-Leu-Arg. Grade: 96.7%. Molecular formula: C132H208N38O32S. Mole weight: 2871.4. | |
| Ixosin-B | Ixosin-B is an antibacterial peptide isolated from Ixodes sinensis (Hard tick). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ixosin-B-amide; Gln-Leu-Lys-Val-Asp-Leu-Trp-Gly-Thr-Arg-Ser-Gly-Ile-Gln-Pro-Glu-Gln-His-Ser-Ser-Gly-Lys-Ser-Asp-Val-Arg-Arg-Trp-Arg-Ser-Arg-Tyr-NH2. Grade: 97.2%. Molecular formula: C165H263N57O48. Mole weight: 3813.2. | |
| I-XW-053 | I-XW-053 is an inhibitor of HIV-1 capsid protein that can suppress the replication of HIV-189BZ167 with an IC 50 value of 164.2 μM. I-XW-053 exhibits antiviral activity and can block the interface between capsid protein (CA) N-terminal domains (NTD-NTD interface) with micromolar affinity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5496-35-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g; 5 g. Product ID: HY-103078. | |
| Izalontamab | Izalontamab (SI-B001) is a bispecific anti-EGFR/HER3 monoclonal antibody with high selectivity for EGFR/HER3 heterodimer. Izalontamab can be used for the research of cancer[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SI-B001. CAS No. 2559704-24-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99676. | |
| Izencitinib | Izencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor. Izencitinib (TD-1473) can be used in the study for ulcerative colitis[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-1473; JNJ-8398. CAS No. 2051918-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109148. | |
| Izumenolide | It is produced by the strain of Micromonospora chalcea subsp. izumensis. Izumenolide inhibited some β-lactamases, and the IC50 concentration of TEM-2 β-lactamase was 0.01 μg/mL. Synonyms: EM-4615-A; Oxacyclotriacont-3-en-2-one, 16,18-bis(sulfooxy)-30-(2-(sulfooxy)-9-undecenyl)-. CAS No. 76265-39-9. Molecular formula: C40H74O14S3. Mole weight: 875.20. | |
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