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| Product | Description | |
|---|---|---|
| Ivermectin B1a-D2 | Ivermectin B1a-D2. Alternative Names: 5-O-Demethyl-22,23-dihydro-avermectin A1a-D2. CAS No. 71827-03-7 (Unlabelled). Purity: 94%. Product ID: ACM71827037-2. Molecular formula: C48H72D2O14. Mole weight: 877.11. IUPAC Name: (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Ivermectin B1a-D2 | Ivermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C48H72D2O14, Molecular Weight: 877.11. US Biological Life Sciences. |  Worldwide |
| Ivermectin B1 Aglycon | Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 73162-95-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C34H50O8. US Biological Life Sciences. | Worldwide |
| Ivermectin B1 Aglycon | Ivermectin B1 Aglycon. Alternative Names: (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. CAS No. 73162-95-5. Purity: 98%. Product ID: ACM73162955. Molecular formula: C34H50O8. Mole weight: 586.76. IUPAC Name: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12,21,24-trihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O)/C)C. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ivermectin B1 aglycone | A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. Grade: >99% by HPLC. CAS No. 123997-59-1. Molecular formula: C34H50O8. Mole weight: 586.76. |  |
| Ivermectin B1b | Ivermectin B1b is the minor component (>20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro tests have found the B1b (25-iso-propyl) analogue to be slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis and also a more sensitive probe for ivermectin resistance. Group: Biochemicals. Alternative Names: Ivermectin B1b, 22, 23-Dihydroavermectin B1b. Grades: Highly Purified. CAS No. 70209-81-3. Pack Sizes: 500ug, 2.5mg. US Biological Life Sciences. | Worldwide |
| Ivermectin B1b | Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Synonyms: Ivermectin B1b; Avermectin H2B1b; Ivermectin Component B1b; dihydroavermectin B1b; 70209-81-3; 22,23-dihydroavermectin B1b; 0W28CYI3TU; CHEBI:63943; Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-; (1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one; UNII-0W28CYI3TU; Stromectol (TN); Soolantra (TN); EINECS 274-384-5; Sklice (TN); H2B1b; CHEMBL552; Ivermectin (JAN/USP/INN); SCHEMBL313003; DTXSID3023182; VARHUCVRRNANBD-PVVXTEPVSA-N; IVERMECTIN COMPONENT B1B [MI]; HY-125729; CS-0093431; NS00093438; D00804; Q27132925; 5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A; Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. Grade: >95% by HPLC. CAS No. 70209-81-3. Molecular formula: C20H38N6O4. Mole weight: 426.6. | |
| Ivermectin B1 monosaccharide | Ivermectin B1 monosaccharide. Alternative Names: 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a. CAS No. 71837-27-9. Purity: 98%. Product ID: ACM71837279. Molecular formula: C41H62O11. Mole weight: 730.94. IUPAC Name: (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)/C)C. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ivermectin B1 Monosaccharide | Ivermectin B1 Mono-sugar Derivative is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Biochemicals. Grades: Highly Purified. CAS No. 71837-27-9. Pack Sizes: 50mg, 500mg. Molecular Formula: C41H62O11. US Biological Life Sciences. | Worldwide |
| Ivermectin-d2 | Isotope labelled Ivermectin, is the labeled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). Group: Biochemicals. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivermectin-d2 | An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Grade: > 95%. Molecular formula: C48H72O14D2. Mole weight: 877.13. | |
| Ivermectin-[d2] | Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2/Covid-19. Synonyms: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Grade: 98% by CP; 97% atom D. Molecular formula: C48H72D2O14. Mole weight: 877.11. | |
| Ivermectin-D2 | Ivermectin-D2. Alternative Names: 22,23-Dihydroavermectin B1-d2. CAS No. 70288-86-7. Purity: 97%. Product ID: ACM70288867. Molecular formula: C48H72D2O14. Mole weight: 877.12. IUPAC Name: (1R,4R,5'S,6R,6'S,8S,10Z,12S,13S,14Z,20R,21S,24S)-6'-[(2S)-butan-2-yl]-21,24-dihydroxy-12-[(2S,4S,5R,6S)-5-[(2R,4S,5R,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one. Canonical SMILES: CC[C@H](C)[C@H]1[C@H](CC[C@@]2(O1)C[C@H]3C[C@@H](O2)C/C=C(\[C@H]([C@H](/C=C\C=C4CO[C@H]5[C@@]4([C@@H](C=C([C@@H]5O)C)C(=O)O3)O)C)O[C@@H]6C[C@@H]([C@@H]([C@@H](O6)C)O[C@@H]7C[C@@H]([C@@H]([C@@H](O7)C)O)OC)OC)/C)C. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ivermectin (Dihydroavermectin B1a, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a ) | Ivermectin B1a is the major component (>80%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectins and milbemycins are also potent insecticides. The individual 25-sec-butyl (B1a) and 25-iso-propyl (B1b) components of ivermectin have received little separate study. Group: Biochemicals. Alternative Names: Ivermectin, Ivermectin B1a, 22, 23-Dihydro-avermectin B1a. Grades: Highly Purified. CAS No. 70161-11-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivermectin EP Impurity C | Ivermectin EP Impurity C. Uses: For analytical and research use. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.11. Catalog: APB65195575. |  |
| Ivermectin EP Impurity D | Ivermectin EP Impurity D is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O-demethyl-28-oxo-22,23-dihydroavermectin A1a; 28-oxoH2B1a; 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.10. | |
| Ivermectin EP Impurity E | Ivermectin EP Impurity E is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-12-ethyl-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1a. Molecular formula: C49H76O14. Mole weight: 889.13. | |
| Ivermectin EP Impurity F | Ivermectin EP Impurity F is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 5-O,12-didemethyl-25-de(1-methylpropyl)-12-ethyl-25-(1-methylethyl)-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1b. Molecular formula: C48H74O14. Mole weight: 875.11. | |
| Ivermectin EP Impurity G | Ivermectin EP Impurity G is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; H2B1a aglycone. Grade: > 95%. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77. | |
| Ivermectin EP Impurity H | Ivermectin EP Impurity H is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: >95%. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. | |
| Ivermectin EP Impurity J | Ivermectin EP Impurity J is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-3,4,22,23-tetrahydroavermectin A1a; Δ2,3H2B1b. Molecular formula: C47H72O14. Mole weight: 861.08. | |
| Ivermectin EP Impurity K | Ivermectin EP Impurity K is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. Grade: > 95%. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13. | |
| Ivermectin impurity 10 | Ivermectin impurity 10. Uses: For analytical and research use. CAS No. 1135339-49-9. Molecular formula: C48H74O14. Mole weight: 875.11. Catalog: APB1135339499. | |
| Ivermectin impurity 11 | Ivermectin impurity 11. Uses: For analytical and research use. Molecular formula: C47H72O14. Mole weight: 861.08. Catalog: APB11124. | |
| Ivermectin impurity 12 | Ivermectin impurity 12. Uses: For analytical and research use. CAS No. 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.12. Catalog: APB74567014. | |
| Ivermectin impurity 13 | Ivermectin impurity 13. Uses: For analytical and research use. Molecular formula: C49H76O14. Mole weight: 889.13. Catalog: APB11125. | |
| Ivermectin impurity 14 | Ivermectin impurity 14. Uses: For analytical and research use. Molecular formula: C49H76O15. Mole weight: 905.13. Catalog: APB11126. | |
| Ivermectin impurity 15 | Ivermectin impurity 15. Uses: For analytical and research use. Molecular formula: C47H72O14. Mole weight: 861.08. Catalog: APB11127. | |
| Ivermectin impurity 16 | Ivermectin impurity 16. Uses: For analytical and research use. CAS No. 431070-70-1. Molecular formula: C47H72O14. Mole weight: 861.08. Catalog: APB431070701. | |
| Ivermectin impurity 17 | Ivermectin impurity 17. Uses: For analytical and research use. CAS No. 127468-07-9. Molecular formula: C48H74O15. Mole weight: 891.11. Catalog: APB127468079. | |
| Ivermectin impurity 18 | Ivermectin impurity 18. Uses: For analytical and research use. Molecular formula: C49H76O15. Mole weight: 905.13. Catalog: APB11128. | |
| Ivermectin impurity 5 | Ivermectin impurity 5. Uses: For analytical and research use. CAS No. 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.09. Catalog: APB102190556. | |
| Ivermectin impurity 6 | Ivermectin impurity 6. Uses: For analytical and research use. Molecular formula: C49H76O14. Mole weight: 889.13. Catalog: APB11122. | |
| Ivermectin impurity 7 | Ivermectin impurity 7. Uses: For analytical and research use. Molecular formula: C48H74O14. Mole weight: 875.11. Catalog: APB11123. | |
| Ivermectin impurity 8 | Ivermectin impurity 8. Uses: For analytical and research use. CAS No. 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77. Catalog: APB73162955. | |
| Ivermectin impurity 9 | Ivermectin impurity 9. Uses: For analytical and research use. CAS No. 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Catalog: APB71837279. | |
| Ivermectin monosaccharide | A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Synonyms: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. Grade: >99% by HPLC. CAS No. 123997-64-8. Molecular formula: C41H62O11. Mole weight: 730.92. | |
| Ivermectin Monosccharide (Dihydroavermectin B1 Monosaccharide, Ivermectin B1 Monosaccharide) | Ivermectin monosaccharide is a semi-synthetic produced by the selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance. Group: Biochemicals. Alternative Names: Dihydroavermectin B1 monosaccharide, Ivermectin B1 monosaccharide. Grades: Highly Purified. CAS No. 123997-64-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) | Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) is a degradation impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Synonyms: (2R,2a'Z,4'E,5S,6R,6'S,7'S,8'E,11'R, 15'S, 17a'R,20'R,20a'S)-6-((S)-sec-butyl)-20'-hydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-17'-oxo-2a1',3,4,5,6,6',10',11',14',15',17',17a',20',20a'-tetra decahydro-2'H,7'H-spir[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-2'-carbaldehyde. | |
| Ivermectin USP | Ivermectin USP. |  CA, FL & NJ |
| Ivicentamab | Ivicentamab (GEN-3009) is a bispecific antibody targeting CD37 with dual epitopes. Ivicentamab carries an E430G mutation in the Fc region, which efficiently promotes IgG hexamer formation on the surface of target cells. Ivicentamab provides the parental variable regions for an H429F-engineered anti-CD37 bispecific antibody, enabling it to exert complement-dependent cytotoxicity in Daudi lymphoma cells. Ivicentamab is mainly used in lymphoma-related research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GEN-3009. CAS No. 2364496-42-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99674. |  |
| Ivonescimab | Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody. Ivonescimab competitively inhibiting PD-1/PD-L1 interaction, reversing the immunosuppression mediated by it, and blocks the binding of VEGF-A to VEGFR2, inhibiting tumour angiogenesis in the tumour microenvironment. Ivonescimab also has significantly anticancer activity against EGFR-mutated locally advanced or metastatic non-squamous non-small cell lung cancer (NSCL)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK112. CAS No. 2428381-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99675. | |
| Ivosidenib | Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular differentiation and inhibit cellular proliferation in IDH1-expressing tumor cells. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 1448347-49-6. Product ID: API1448347496. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.96. Standard: GMP. |  |
| Ivosidenib | Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-120. CAS No. 1448347-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18767. | |
| Ivospemin | Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SBP-101. CAS No. 748119-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132822. | |
| IVQRFKDFRNLVRLIK | IVQRFKDFRNLVRLIK. Synonyms: Ile-Val-Gln-Arg-Phe-Lys-Asp-Phe-Arg-Asn-Leu-Val-Arg-Leu-Ile-Lys. Molecular formula: C95H161N29O21. Mole weight: 2045.52. | |
| Ivuxolimab | Ivuxolimab is a fully human IgG2 agonist targeting OX40 (CD134), which selectively binds to the OX40 receptor on the surface of activated CD4+ and CD8+ T cells without inducing antibody-dependent cytotoxicity. Ivuxolimab can promote T cell proliferation, survival and cytokine (such as IFN-γ, IL-2) secretion, inhibit regulatory T cell function, and enhance anti-tumor immune response. Ivuxolimab can be used in the study of melanoma, hepatocellular carcinoma, head and neck squamous cell carcinoma, etc[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2128729-41-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99159. | |
| Ivy Base | Ivy Base. CAS No. MIXTURE. VIGON Item # 504914. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Ivy Extract | Ivy extract is prepared from leaf and stem of araliaceae family plant Hedera nepalensis var. sinensis (tobl.) rehd. Ivy extract is a product that widely used in medicine and cosmetics. Ivy extract has the function of moisturizing skin, and reducing wrinkles on face. Group: Others. Mole weight: 472.7. Ivy Extract; Hedera Nepalensis Var. Sinensis (Tobl.) Rehd. Cat No: EXTC-059. |  |
| Ivy Extract (Hederacoside C) | Ivy Extract (Hederacoside C). CAS No. 84082-54-2. Purity: 5-45%. Product ID: CI-NAT-84082542. Molecular formula: C59H96O26. Mole weight: 1221.38 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Ivy P.E. 4:1 (Hedera helix) | Ivy P.E. 4:1 (Hedera helix). | CA, FL & NJ |
| IWP 12 | IWP 12. Group: Biochemicals. Grades: Purified. CAS No. 688353-45-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IWP 2 | IWP 2. Group: Biochemicals. Grades: Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IWP-2 | IWP-2. Group: Biochemicals. Alternative Names: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide. Grades: Highly Purified. CAS No. 686770-61-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H18N4O2S3. US Biological Life Sciences. | Worldwide |
| IWP-2 | IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 686770-61-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13912. | |
| IWP-2 | IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ. Group: Inhibitors. CAS No. 686770-61-6. Pack Sizes: 10mg. Product ID: S7085. Formula: C22H18N4O2S3. Smiles: CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=CC=C5)SCC4. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| IWP-2 (N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide) | Cell-permeable. Acts as an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50 = 27nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| IWP-3 | IWP-3 is an potent inhibitor of Wnt production with an IC50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1γ3 and CK1ε only moderately and does not inhibit CK1α[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 687561-60-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100536. | |
| IWP-3 (Inhibitor of Wnt Production-3) | IWP-3 (Inhibitor of Wnt Production-3). Group: Biochemicals. Alternative Names: 2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N- (6-methyl-2-benzothiazolyl)-acetamide. Grades: Highly Purified. CAS No. 687561-60-0. Pack Sizes: 10mg. Molecular Formula: C22 H17 FN 4O2S3 , Molecular Weight: 484.6. US Biological Life Sciences. | Worldwide |
| IWP 4 | IWP 4. Group: Biochemicals. Grades: Purified. CAS No. 686772-17-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IWP-4 | IWP-4 is a Wnt inhibitor with an IC50 of 25 nM. IWP-4 specifically inhibits casein kinase 1δ/ε (CK1δ/ε), with an IC50 of 1.06 μM against wild-type CK1δ, 1.02 μM against the CK1δ kinase domain, and 7.07 μM against CK1ε; it shows enhanced inhibitory activity against the M82F CK1δ mutant (IC50 = 0.14 μM). IWP-4 is applicable to research related to cancer, Alzheimer's disease (AD), and heart failure[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 686772-17-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12879. | |
| IWP L6 | IWP L6. Group: Biochemicals. Grades: Purified. CAS No. 1427782-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| IWP-O1 | IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2074607-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100853. | |
| IWR-1 | IWR-1. CAS No: 430429-02-0 |  Sarchem Laboratories New Jersey NJ |
| IWR-1 | IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC50 = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis[1][2][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: endo-IWR 1; IWR-1-endo. CAS No. 1127442-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12238. | |
| IWR-1-endo | IWR-1-endo (endo-IWR 1, IWR-1) is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells expressing Wnt3A, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes. Group: Inhibitors. Alternative Names: endo-IWR 1, IWR-1. CAS No. 1127442-82-3. Pack Sizes: 10mg. Product ID: S7086. Formula: C25H19N3O3. Smiles: C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| IWR-1 (IWR-1-endo) | Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3 β. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3 β. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay). Group: Biochemicals. Alternative Names: 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide. Grades: Highly Purified. CAS No. 1127442-82-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 409.4. US Biological Life Sciences. | Worldwide |
| IXA4 | IXA4 is a highly selective, non-toxic IRE1/XBP1s activator. IXA4 activates IRE1/XBP1s signaling without globally activating the unfolded protein response (UPR) or other stress-responsive signaling pathways (e.g., the heat shock response or oxidative stress response). IXA4 reduces secretion of APP through IRE1 activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1185329-96-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139214. | |
| IXA6 | IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1021106-40-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-139212. | |
| IXA62 | IXA62 is an orally active and selective IRE1/XBP1s activator (EC50 = 0.31 μM) that reduces Aβ secretion. IXA62 enhances glucose-stimulated insulin secretion from rat insulinoma cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 956783-34-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-176040. | |
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