A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. Synonyms: C646; C-646; C 646. Grade: >98%. CAS No. 328968-36-1. Molecular formula: C24H19N3O6. Mole weight: 445.42.
C646
Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines. Group: Biochemicals. Alternative Names: (E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid. Grades: Highly Purified. CAS No. 328968-36-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C24H19N3O6. US Biological Life Sciences.
Worldwide
C646
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases. C646 induces cell cycle arrest, apoptosis and autophagy. Group: Inhibitors. CAS No. 328968-36-1. Pack Sizes: 10mg. Product ID: S7152. Formula: C24H19N3O6. Smiles: CC1=CC(=C(C=C1C)[N+](=O)[O-])C2=CC=C(O2)C=C3C(=NN(C3=O)C4=CC=C(C=C4)C(=O)O)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
C646
C646 is a selective and competitive histone acetyltransferase p300 inhibitor with Ki of 400 nM, and is less potent for other acetyltransferases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 328968-36-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-13823.
C 646
C 646. Group: Biochemicals. Grades: Purified. CAS No. 328968-36-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
C6(6-azido) GalCer
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Galactosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Galactosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-20-8. Molecular formula: C30H56N4O8. Mole weight: 600.79.
C6(6-azido) GluCer
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Gluctosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Gluctosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[(β-D-glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-21-9. Molecular formula: C30H56N4O8. Mole weight: 600.79.
C6(6-azido) LacCer
It is a modified lipid containing an omega-terminal azide. In the presence of a coppery(Cu)-containing catalyst, the terminal azide group can be used for highly specific binding reactions with alkyne-containing reagents, known as ''click chemistry''. Synonyms: D-Lactosyl-β-1,1'-N-(6''-azidohexanoyl)-D-erythro-sphingosine; C6(6-azido) Lactosyl(β) Ceramide; 6-Azido-N-[(1S,2R,3E)-1-[[(4-O-β-D-galactopyranosyl-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]hexanamide. Grade: >99%. CAS No. 2260670-19-5. Molecular formula: C36H66N4O13. Mole weight: 762.93.
C6 Biotin Ceramide (d18:1/6:0)
C6 Ceramide-biotin is an affinity probe that allows C2 ceramide (d18:1/2:0) to be detected or immobilized through interaction with the biotin ligand. It has been used to detect ceramide binding partners, such as inhibitor 2 of protein phosphatase 2A (I2PP2A). C6 ceramide mediates many diverse biological activities including apoptosis, activation of PP2A, and inhibition of the mitochondrial respiratory chain. It also enhances the expression of COX-2 in rat granulosa cells and stimulates the growth of bovine aortic smooth muscle cells. Synonyms: Biotin Ceramide (d18:1/6:0); Biotin Cer(d18:1/6:0); C6 Ceramide-biotin; N-C6:0-biotin-D-erythro-Ceramide; N-hexanoyl-biotin-D-erythro-sphingosine. Grade: ≥98%. Molecular formula: C34H62N4O5S. Mole weight: 638.9.
C6 Ceramide
C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis, inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C6-Cer; N-Hexanoylsphingosine. CAS No. 124753-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19542.
C6-Ceramide
C6-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexanamide; N-Hexanoy-D-sphingosine; N-Hexanoylsphingosine. Grades: Highly Purified. CAS No. 124753-97-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H47NO3. US Biological Life Sciences.
Worldwide
C6 Ceramide-13C2,d2
A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway. Group: Biochemicals. Alternative Names: N-Hexanoy-D-sphingosine-13C2,d2; N-Caproyl-D-sphingosine-13C2,d2; Caproyl Ceramide-13C2,d2. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
C6 ceramide-1,3-cyclic-phosphate (d18:1/6:0)
C6 ceramide-1,3-cyclic-phosphate (d18:1/6:0). Alternative Names: N-hexanoyl-ceramide-1,3-cyclic-phosphate (ammonium salt). CAS No. 2410310-25-5. Purity: >99%. Product ID: ALCFA2410310255. Molecular formula: C24H49N2O5P. Mole weight: 476.64. Alfa Chemistry - ISO 9001:32057 Certified.
C6 dihydroceramide
C6 dihydroceramide. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -2-Hydroxy-1- (hydroxymethyl) heptadecyl]hexanamide; N-Hexanoylsphinganine. Grades: Highly Purified. CAS No. 171039-13-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H49NO3. US Biological Life Sciences.
Worldwide
C6 Dihydroceramide (N-Hexanoylsphinganine)
May be used as a negative control for C6 Ceramide. Group: Biochemicals. Alternative Names: N-Hexanoylsphinganine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
C6 NBD Sphingomyelin
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94885-04-8. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-D1574.
C6-Sphingosine
C6-Sphingosine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C6H13NO2, Molecular Weight: 131.169999999999. US Biological Life Sciences.
Worldwide
C7280948
C7280948 is a novel PRMT1 inhibitor ( IC50=12.75 μM). Uses: A novel prmt1 inhibitor. Synonyms: C7280948; C-7280948; C 7280948; 4-amino-N-(2-phenylethyl)benzenesulfonamide; 4-amino-N-phenethylbenzenesulfonamide. Grade: ≥95%. CAS No. 587850-67-7. Molecular formula: C14H16N2O2S. Mole weight: 276.35.
C75
C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS), which is used as a tool for studying fatty acid synthesis in metabolic disorders and cancer. Synonyms: C 75 trC-75 trans-racemic; trans-C75; C 75; C75; C-75. Grade: >98%. CAS No. 218137-86-1. Molecular formula: C14H22O4. Mole weight: 254.32.
C75
C75 is a synthetic fatty-acid synthase (FASN) inhibitor; inhibits prostate cancer cells PC3 with an IC50 of 35 μM[1][2][3]. C75 is a potent CPT1A activator[5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 218137-86-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12364.
C75 trans
trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a well-known fatty acid synthase (FAS) inhibitor. Studies show that trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic Acid is a cell cycle arrest inducer in hepatocellular carcinoma (HCC) cell lines. It has also been shown to blocks resistin-induced increases in lipid accumulation by human macrophages. Synonyms: C 75 trC-75 trans-racemic; trans-C75. Grade: >98%. CAS No. 191282-48-1. Molecular formula: C14H22O4. Mole weight: 254.32.
C791-0064
C791-0064 is a RAD52 inhibitor. C791-0064 specifically binds to RAD52 and disrupts its single-strand annealing activity. C791-0064 specifically inhibits the proliferation of cancer cells with BRCA2 deficiency, inducing DNA damage and apoptosis (apoptosis). C791-0064 can be used for the study of BRCA mutation-related cancers (such as breast cancer and ovarian cancer)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902940-64-1. Pack Sizes: 1 mg. Product ID: HY-153338.
C7-cyclitol 7-kinase
The enzyme, characterized from the bacterium Streptomyces hygroscopicus var. jinggangensis, is involved in the biosynthesis of the antifungal agent validamycin A. Group: Enzymes. Synonyms: valC (gene name); vldC (gene name). Enzyme Commission Number: EC 2.7.1.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3050; C7-cyclitol 7-kinase; EC 2.7.1.214; valC (gene name); vldC (gene name). Cat No: EXWM-3050.
C8:0 L-carnitine-d9
C8:0 L-carnitine-d9. Alternative Names: Octanoyl L-carnitine-d9. CAS No. 2847775-88-4. Purity: >99%. Product ID: ALCFA2847775884. Molecular formula: C15H20D9NO4. Mole weight: 296.45. Alfa Chemistry - ISO 9001:32057 Certified.
C 87
C 87 is a TNF-α inhibitor (Kd = 110 nM for hTNF-α). It was shown to inhibit TNF-α-induced cytotoxicity in L929 fibroblast cells, attenuate inflammation and increase survival in a mouse hepatitis model. Synonyms: TNFalpha-IN-C87; 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone]. Grade: ≥98% by HPLC. CAS No. 332420-90-3. Molecular formula: C24H15ClN6O3S. Mole weight: 502.93.
C 87
C 87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 332420-90-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100735.
c[8-AET-G(2',5')pA(3',5')p]
c[8-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which is used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- (2- aminoethylthio)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C22H29N11O13P2S (free acid). Mole weight: 749.6 (free acid).
c[8-AET-G(2',5')pA(3',5')p]-Agarose
c[8-AET-G(2',5')pA(3',5')p]-Agarose is the metazoan cyclic dinucleotide second messenger c[G(2',5)pA(3',5')p] immobilized on agarose by an aminoethylthio spacer, which possibly can be used in affinity chromatography of c[G(2',5')pA(3',5')p]-responsive proteins. Synonyms: Cyclic (8- (2- aminoethylthio)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), immobilized on agarose gel.
C8-Alkyne-dCTP
C8-Alkyne-dCTP is a modified nucleoside triphosphate utilized in the field of DNA research. Its unique chemical structure enables it to be incorporated into DNA sequences during polymerase chain reaction (PCR), allowing for the detection and analysis of DNA-protein interactions. C8-Alkyne-dCTP is commonly used in studies focused on drug discovery and disease diagnosis within the biomedical industry. Synonyms: 5-(Octa-1,7-diynyl)-2'-deoxycytidine 5'-triphosphate, Sodium salt. Grade: ≥ 99%. Molecular formula: C17H24N3O13P3 (free acid). Mole weight: 571.31 (free acid).
C8-Alkyne-dUTP
C8-Alkyne-dUTP can be incorporated into DNA by PCR with family B polymerases to produce modified DNA. Synonyms: 5-(Octa-1,7-diynyl)-2'-deoxyuridine 5'-triphosphate, Sodium salt. Grade: ≥ 99%. Molecular formula: C17H23N2O14P3 (free acid). Mole weight: 572.29 (free acid).
c[8-Biotin-11-G(2',5')pA(3',5')p]
c[8-Biotin-11-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Grade: ≥ 95% by HPLC. Molecular formula: C38H54N14O16P2S2 (free acid). Mole weight: 1089 (free acid).
c[8-Br-G(2',5')pA(3',5')p]
c[8-Br-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger, which can be used for binding studies and as precursor for further modifications with spacers or labels. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- bromoguanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O13P2 (free acid). Mole weight: 753.3 (free acid).
C8-BTBT
C8-BTBT is a conducting polymer with benzothieno[3,2-b]- benzothiophene (BTBT) as the base material for the development of air-stable semiconductors. It can form a spin coated thin film that can be used as a p-type semiconductor with charge mobility of 43 cm2 V-1s-1. It exhibits highly ordered self-assembled monolayer (SAM) on graphene and hexagonal boron nitride (hBN) with sheet resistance: <1,000 ohm/sq. Alternative Names: 2,7-Dioctyl[1]benzothieno[3,2-b][1]benzothiophene. CAS No. 583050-70-8. Molecular formula: C30H40S2. Mole weight: 464.77. IUPAC Name: 2,7-dioctyl-[1]benzothiolo[3,2-b][1]benzothiole. SMILES: CCCCCCCCC1=CC2=C(C=C1)C3=C(C(C=CC(CCCCCCCC)=C4)=C4S3)S2. InChI: 1S/C30H40S2/c1-3-5-7-9-11-13-15-23-17-19-25-27(21-23)31-30-26-20-18-24(22-28(26)32-29(25)30)16-14-12-10-8-6-4-2/h17-22H,3-16H2,1-2H3,YWIGIVGUASXDPK-UHFFFAOYSA-N.
c-8 Ceramide-1-phosphate. Alternative Names: D-ERYTHRO-SPHINGOSINE-1-PHOSPHATE, N-OCTANOYL-;C8 CERAMIDE-1-PHOSPHATE;N-OCTANOYLSPHINGOSINE-1-PHOSPHATE. CAS No. 158983-53-0. Product ID: ACM158983530. Molecular formula: C26H52NO6P. Mole weight: 365.4. Alfa Chemistry - ISO 9001:32057 Certified.
C8 ceramide-1-phosphate
C8 ceramide-1-phosphate. Group: Biochemicals. Alternative Names: N-[2-Hydroxy-1-[(phosphonooxy)methyl]-3-heptadecen-1-yl]octanamide; N-Octanoylsphingosine-1-phosphate. Grades: Highly Purified. CAS No. 887353-95-9. Pack Sizes: 1mg. Molecular Formula: C26H52NO6P. US Biological Life Sciences.
Worldwide
C-8 Ceramide-1-phosphate
C-8 Ceramide-1-phosphate is a cell apoptosis inhibitor and a cell survival inducer that can stimulate DNA synthesis and cell division. C-8 Ceramide-1-phosphate can inhibit acidic sphingomyelinase (SMase) and stimulate PI3-K, which in turn produces PIP3; PIP3 can also inhibit acidic SMase. The C-8 Ceramide-1-phosphate and ceramide can be interconverted in cells through kinase and phosphatase activity, and maintaining the balance between the two is crucial for cellular and tissue homeostasis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 158983-53-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-165099.
C8 Ceramide-1-Phosphate (d17:1/8:0)
C8 Ceramide-1-Phosphate (d17:1/8:0). Alternative Names: CerP(d17:1/8:0). CAS No. 474944-04-2. Purity: >99%. Product ID: ALCFA474944042. Molecular formula: C25H53N2O6P. Mole weight: 508.672. Alfa Chemistry - ISO 9001:32057 Certified.
C8 Ceramide-1-Phosphate (d18:1/8:0)
C8 Ceramide-1-Phosphate (d18:1/8:0). Alternative Names: N-(octanoyl)-sphing-4-enine-1-phosphate CerP(d18:1/8:0). CAS No. 474943-70-9. Purity: >99%. Product ID: ALCFA474943709. Molecular formula: C26H55N2O6P. Mole weight: 522.698. Alfa Chemistry - ISO 9001:32057 Certified.
Stimulates DNA synthesis when added exogenously to cultured fibroblasts at 5μM. Mitogenic activity is antagonized by cell permeable ceramides. Group: Biochemicals. Alternative Names: N-Octanoylsphingosine-1-phosphate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
C8 dihydroceramide
C8 dihydroceramide. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -2-Hydroxy-1- (hydroxymethyl) heptadecyl]octanamide; N-Octanoylsphinganine. Grades: Highly Purified. CAS No. 145774-33-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H53NO3. US Biological Life Sciences.
Worldwide
C8 Dihydroceramide (N-Octanoylsphinganine)
May be used as a negative control for C8 Ceramide. Group: Biochemicals. Alternative Names: N-Octanoylsphinganine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
c[8-Fluo-AET-G(2',5')pA(3',5')p]
c[8-Fluo-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Synonyms: Cyclic(8-(2-[fluoresceinyl]aminoethylthio)-guanosine-(2'→5')-monophosphate-adenosine-(3'→5')-monophosphate), sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C43H39N11O19P2S (free acid). Mole weight: 1107.9 (free acid).
CA 074 is a potent and selective inhibitor of cathepsin B (Ki = 2-5 nM). It reduces bone metastasis in a 4T1.2 breast cancer model. Uses: Cysteine proteinase inhibitors. Synonyms: CA-074; CA074; CA 074; N-[[(2S,3S)-3-[(Propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline. Grade: ≥98% by HPLC. CAS No. 134448-10-5. Molecular formula: C18H29N3O6. Mole weight: 383.44.
CA 074
CA 074. Group: Biochemicals. Grades: Purified. CAS No. 134448-10-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CA-074
CA-074 is a potent inhibitor of cathepsin B with a Ki of 2 to 5 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 134448-10-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103350.
CA-074 methyl ester is a specific inhibitor of Cathepsin B, which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CA-074Me. CAS No. 147859-80-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100350.
CA-074 methyl ester
CA-074 Me is a membrane-permeable inhibitor of irreversible cathepsin B derived from CA-074. CA-074 Me would be hydrolyzed by intracellular esterases to CA-074, the active compound. Synonyms: Ca-074Me; Ca 074Me; Ca074Me; Cathepsin B Inhibitor IV; MFCD03452890; (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylate; CA-074 Me. Grade: 99.04 %. CAS No. 147859-80-1. Molecular formula: C19H31N3O6. Mole weight: 397.47.
CA-074 methyl ester (CA-074 Me)
CA-074 methyl ester (CA-074 Me, Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor. Group: Inhibitors. Alternative Names: Cathepsin B Inhibitor IV. CAS No. 147859-80-1. Pack Sizes: 5mg. Product ID: S7420. Formula: C19H31N3O6. Smiles: CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC. Storage Conditions: 2 years -80 in solvent.
United States; Europe
CA-170
CA-170 is an orally delivered dual inhibitor of VISTA and PD-L1. CA-170 exhibits potent rescue of proliferation and effector functions of T cells inhibited by PD-L1/L2 and VISTA with selectivity over other immune checkpoint proteins as well as a broad panel of receptors and enzymes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1673534-76-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101093.
c[A(2',5')pA(2',5')p]
c[A(2',5')pA(2',5')p] is a cyclic dinucleotide analogue of c-diAMP, the bacterial second messenger. Synonyms: Cyclic (adenosine- (2' -≥ 5')- monophosphate- adenosine- (2' -≥ 5')- monophosphate), sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H24N10O12P2. Mole weight: 658.4.
c[A(2',5')pS[Sp]-A(3',5')pS[Rp]]
c[A(2',5')pS[Sp]-A(3',5')pS[Rp]] is asyntheticdi-thiophosphate analogue of c[A(2',5')pA(3',5')p] with higher stability resisting degradation by phosphodiesterases. Grade: ≥ 95% by HPLC. CAS No. 1638242-31-5. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid).