A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Saccharin Impurity 1. Uses: For analytical and research use. CAS No. 26638-43-7. Molecular formula: C8H7ClO4S. Mole weight: 234.65. Catalog: APB26638437.
Saccharin Impurity 10
Saccharin Impurity 10. Uses: For analytical and research use. CAS No. 119591-34-3. Molecular formula: C7H4INO3S. Mole weight: 309.08. Catalog: APB119591343.
Saccharin Impurity 11
Saccharin Impurity 11. Uses: For analytical and research use. CAS No. 221446-00-0. Molecular formula: C8H5NO5S. Mole weight: 227.19. Catalog: APB221446000.
Saccharin Impurity 12
Saccharin Impurity 12. Uses: For analytical and research use. CAS No. 384-45-2. Molecular formula: C7H4FNO3S. Mole weight: 201.17. Catalog: APB384452.
Saccharin Impurity 13
Saccharin Impurity 13. Uses: For analytical and research use. CAS No. 29632-82-4. Molecular formula: C7H4BrNO3S. Mole weight: 262.08. Catalog: APB29632824.
Saccharin Impurity 14
Saccharin Impurity 14. Uses: For analytical and research use. CAS No. 29083-18-9. Molecular formula: C7H4FNO3S. Mole weight: 201.17. Catalog: APB29083189.
Saccharin Impurity 15
Saccharin Impurity 15. Uses: For analytical and research use. CAS No. 1647073-46-8. Molecular formula: C8H4F3NO3S2. Mole weight: 283.24. Catalog: APB1647073468.
Saccharin Impurity 16
Saccharin Impurity 16. Uses: For analytical and research use. CAS No. 35812-01-2. Molecular formula: C7H4BrNO3S. Mole weight: 262.08. Catalog: APB35812012.
Saccharin Impurity 2
Saccharin Impurity 2. Uses: For analytical and research use. CAS No. 50978-45-5. Molecular formula: C8H5NO4S. Mole weight: 211.19. Catalog: APB50978455.
Saccharin Impurity 3
Saccharin Impurity 3. Uses: For analytical and research use. CAS No. 86340-94-5. Molecular formula: C7H4INO3S. Mole weight: 309.08. Catalog: APB86340945.
Saccharin Impurity 4
Saccharin Impurity 4. Uses: For analytical and research use. CAS No. 136526-27-7. Molecular formula: C8H7NO3S. Mole weight: 197.21. Catalog: APB136526277.
Saccharin Impurity 5
Saccharin Impurity 5. Uses: For analytical and research use. CAS No. 76508-37-7. Molecular formula: C12H13NO5S. Mole weight: 283.3. Catalog: APB76508377.
Saccharin Impurity 6
Saccharin Impurity 6. Uses: For analytical and research use. CAS No. 24683-20-3. Molecular formula: C11H11NO5S. Mole weight: 269.27. Catalog: APB24683203.
Saccharin Impurity 7
Saccharin Impurity 7. Uses: For analytical and research use. CAS No. 22094-61-7. Molecular formula: C7H6N2O3S. Mole weight: 198.2. Catalog: APB22094617.
Saccharin Impurity 8
Saccharin Impurity 8. Uses: For analytical and research use. CAS No. 62473-92-1. Molecular formula: C7H4BrNO3S. Mole weight: 262.08. Catalog: APB62473921.
Saccharin Impurity 9
Saccharin Impurity 9. Uses: For analytical and research use. CAS No. 46149-10-4. Molecular formula: C7H4ClNO3S. Mole weight: 217.62. Catalog: APB46149104.
Saccharin N-(2-acetic acid isopropyl ester)(piroxicam impurity F). Group: Biochemicals. Alternative Names: 3-Oxo-1,2-benzisothiazole-2(3H)-acetic Acid 1-Methylethyl Ester 1,1-Dioxide. Grades: Highly Purified. CAS No. 76508-37-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H13NO5S. US Biological Life Sciences.
Worldwide
Saccharin sodium
Saccharin sodium. CAS No. 128-44-9. Product ID: PE-0004. Molecular formula: C7H5NNaO3S. Mole weight: 206.17. Category: Corrective Excipients. Product Keywords: Pharmaceutical Excipients; Liquid Dosage Form; Corrective Excipients; Saccharin sodium; PE-0004; C7H5NNaO3S; 128-44-9; 128-44-9. Appearance: White crystals or a white, crystalline efflorescent powder. Purity: 0.99. EC Number: 204-886-1. Synonym(s): 1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodium salt;Sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one;2-Sodio-1,2-benzisothiazol-3(2H)-one 1,1-dioxide. Solubility: H2O: 1 M at 20 °C, clear, colorless; sparingly soluble in ethanol. Storage: 0-6°C. Melting Point: >300°C. Density: 1.69[at 20°C].
Saccharin sodium
Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 128-44-9. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g; 5 g. Product ID: HY-B1390A.
Saccharin Sodium BP
Saccharin Sodium BP. CAS No. 82385-42-0. Molecular formula: C7H4NNaO3S.xH2O.
Saccharin sodium salt
Saccharin sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 128-44-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C7H4NNaO3S. US Biological Life Sciences.
Worldwide
Saccharin Sodium Salt Dihydrate
Saccharin Sodium Salt Dihydrate is a non-nutritive sweetener; pharmaceutic aid (flavor). Saccharin was formerly listed as reasonably anticipated to be a human carcinogen; delisted because the cancer data are not sufficient to meet the current criteria for this listing. Group: Biochemicals. Grades: Highly Purified. CAS No. 6155-57-3. Pack Sizes: 5g, 25g. Molecular Formula: C7H4NNaO3S; 2(H2O). US Biological Life Sciences.
Worldwide
Saccharin USP
Saccharin USP. CAS No. 81-07-2. Molecular formula: C7H5NO3S. Categories: 81-07-2.
Saccharocarcin A
An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1→4)-2,6-dideoxyhexopyranosyl]oxy]-15-ethyl-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grade: >95% by HPLC. CAS No. 158475-32-2. Molecular formula: C67H101NO20. Mole weight: 1240.51.
Saccharocarcin A
Saccharocarcin A is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Limited availability has restricted further investigation of this metabolite in the literature. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 158475-32-2. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Saccharocarcin B
Saccharocarcin B is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcins and versipelostatin which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Limited availability has restricted further investigation of this metabolite in the literature. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Grades: Highly Purified. CAS No. 158475-33-3. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Saccharocarcin B
An unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcin and versipelostatin; has pronounced activity against gram positive bacteria and chlamydia trachomatis; inhibits transcription from the promoter of GRP78; appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1→4)-2,6-dideoxyhexopyranosyl]oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20b-dodecahydro-21-hydroxy-1,3,7,9,11,20a-hexamethyl-15-propyl-18H-16a,19-metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione. Grade: >99% by HPLC. CAS No. 158475-33-3. Molecular formula: C68H103NO20. Mole weight: 1254.54.
Saccharocin
Saccharocin is produced by the strain of Saccharopolyspora sp. AC-3440. It is effective against gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria. Synonyms: KA-5685. CAS No. 86630-31-1. Molecular formula: C21H40N4O12. Mole weight: 540.56.
saccharolysin
An 83 kDa cytoplasmic thiol-dependent metalloendopeptidase from Saccharomyces cerevisiae. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Enzyme Commission Number: EC 3.4.24.37. CAS No. 96779-48-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4319; saccharolysin; EC 3.4.24.37; 96779-48-5; proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD. Cat No: EXWM-4319.
Saccharomyces is a genus of fungi that includes many species of yeasts. Saccharomyces is from Greek (sugar) and (mushroom) and means sugar fungus. Many members of this genus are considered very important in food production. It is known as the brewer's yeast or baker's yeast. They are unicellular and saprophytic fungi. One example is Saccharomyces cerevisiae, which is used in making wine, bread, and beer. Other members of this genus include the wild yeast Saccharomyces paradoxus that is the closest relative to S. cerevisiae, Saccharomyces bayanus, used in making wine, and Saccharomyces boulardii, used in medicine. Group: Others. Synonyms: Saccharomyces Freeze Dried Powder; Saccharomyces. Saccharomyces Freeze Dried Powder; Saccharomyces. Cat No: PRBT-038.
saccharopepsin
Located in the vacuole of the bakers yeast (Saccharomyces cerevisiae) cell. In peptidase family A1 (pepsin A family). Group: Enzymes. Synonyms: yeast endopeptidase A; Saccharomyces aspartic proteinase; aspartic proteinase yscA; proteinase A; proteinase yscA; yeast proteinase A; Saccharomyces cerevisiae aspartic proteinase A; yeast proteinase A; PRA. Enzyme Commission Number: EC 3.4.23.25. CAS No. 37228-80-1. Proteinase A. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4263; saccharopepsin; EC 3.4.23.25; 37228-80-1; yeast endopeptidase A; Saccharomyces aspartic proteinase; aspartic proteinase yscA; proteinase A; proteinase yscA; yeast proteinase A; Saccharomyces cerevisiae aspartic proteinase A; yeast proteinase A; PRA. Cat No: EXWM-4263.
Saccharopine
Saccharopine (L-Saccharopine), a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine by the lysine-ketoglutarate reductase. Saccharopine is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine impairs development by disrupting mitochondrial homeostasis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L-Saccharopine. CAS No. 997-68-2. Pack Sizes: 1 mg. Product ID: HY-W040307.
The activities of this enzyme along with EC 1.5.1.8, saccharopine dehydrogenase (NADP+, L-lysine-forming), occur on a single protein. Group: Enzymes. Synonyms: dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming); saccharopin dehydrogenase; NAD+ oxidoreductase (L-2-aminoadipic-Δ-semialdehyde and glutamate forming); aminoadipic semialdehyde synthase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). Enzyme Commission Number: EC 1.5.1.9. CAS No. 37256-26-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1536; saccharopine dehydrogenase (NAD+, L-glutamate-forming); EC 1.5.1.9; 37256-26-1; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming); saccharopin dehydrogenase; NAD+ oxidoreductase (L-2-aminoadipic-Δ-semialdehyde and glutamate forming); aminoadipic semialdehyde synthase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). Cat No: EXWM-1536.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: lysine-2-oxoglutarate reductase; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming); ε-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming); N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming); 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming). Enzyme Commission Number: EC 1.5.1.7. CAS No. 9073-96-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1534; saccharopine dehydrogenase (NAD+, L-lysine-forming); EC 1.5.1.7; 9073-96-5; lysine-2-oxoglutarate reductase; dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming); ε-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming); N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming); 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming). Cat No: EXWM-1534.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase; aminoadipic semialdehyde-glutamic reductase; aminoadipate semialdehyde-glutamate reductase; aminoadipic semialdehyde-glutamate reductase; ε-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming); saccharopine reductase; 6-N-(L-1,3-dicar. Enzyme Commission Number: EC 1.5.1.10. CAS No. 9033-55-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1494; saccharopine dehydrogenase (NADP+, L-glutamate-forming); EC 1.5.1.10; 9033-55-0; saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase; aminoadipic semialdehyde-glutamic reductase; aminoadipate semialdehyde-glutamate reductase; aminoadipic semialdehyde-glutamate reductase; ε-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming); saccharopine reductase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming). Cat No: EXWM-1494.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in lysine biosynthesis and lysine degradation. Group: Enzymes. Synonyms: lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase; L-lysine-α-ketoglutarate reductase; lysine:α-ketoglutarate:TPNH oxidoreductase (ε-N-[gultaryl-2]-L-lysine forming); saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming). Enzyme Commission Number: EC 1.5.1.8. CAS No. 9031-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1535; saccharopine dehydrogenase (NADP+, L-lysine-forming); EC 1.5.1.8; 9031-19-0; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase; L-lysine-α-ketoglutarate reductase; lysine:α-ketoglutarate:TPNH oxidoreductase (ε-N-[gultaryl-2]-L-lysine forming); saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase; 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming). Cat No: EXWM-1535.
S-Acetamidomethyl-3-mercaptopropionic acid
S-Acetamidomethyl-3-mercaptopropionic acid. Group: Biochemicals. Alternative Names: S-Acetamidomethyl-deamino-cysteine. Grades: Highly Purified. CAS No. 52574-08-0. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C6H11NO3S. US Biological Life Sciences.
S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine is a cysteine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19746-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g. Product ID: HY-W004153.
S-Acetyl-3-mercaptopropionic acid-N-hydroxysuccinimide ester ≥97% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
S-Acetyl-coenzyme A synthetase from baker's yeast (S. cerevisiae)
S-Acetyl-coenzyme A synthetase from baker's yeast (S. cerevisiae). Uses: For analytical and research use. CAS No. 9012-31-1. EC Number: 232-729-7. Catalog: AP9012311.
S-Acetyl-L-Glutathione(Italian & Chinese)
S-Acetyl-L-Glutathione(Italian & Chinese).
CA, FL & NJ
S-Acetylmercaptosuccinic anhydride
S-Acetylmercaptosuccinic anhydride. Group: Biochemicals. Grades: Highly Purified. CAS No. 6953-60-2. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
S-Acetylmercaptosuccinic anhydride 99+% (NMR)
S-Acetylmercaptosuccinic anhydride 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
S-Acetyl-PEG3-azide
S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1310827-26-9. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-140859.
S-acetyl-PEG4-propargyl
S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1422540-88-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-141350.
Used for linking synthetic peptide antigens to MAP core peptides or carrier proteins for the purpose of raising antibodies. Synonyms: SAMA-OPfp; Pentafluorophenyl-S-acetylthioglycolate. Grade: ≥ 98 % (HPLC). CAS No. 129815-48-1. Molecular formula: C10H5O3F5S. Mole weight: 300.10.
S-Acetylthioglycolic acid pentafluorophenyl ester 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Sacituzumab
Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HRS7; hRS7. CAS No. 1796566-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99045.
Sacituzumab (anti-Trop-2)
Sacituzumab (anti-Trop-2) is a fully humanized IgG1 kappa monoclonal antibody that binds Trop-2. Group: Antibodies. CAS No. 1796566-95-4. Pack Sizes: 1mg. Product ID: A2031. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Sacituzumab govitecan
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU-132. CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132254.
Sacituzumab govitecan
Sacituzumab govitecan is an antibody-drug conjugate with an SN-38 payload targeting trophoblast cell-surface antigen 2, an epithelial antigen expressed in breast cancer. Synonyms: IMMU-132; IMMU 132; IMMU132. CAS No. 1491917-83-9.
Sacituzumab govitecan
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38, showing anticancer activity. Sacituzumab govitecan has a molecular weight of 160KDa. This product is supplied as 10mg/ml PBS solution. Alternative Names: IMMU-132. CAS No. 1491917-83-9 (Sacituzumab govitecan). Pack Sizes: 1mg. Product ID: D4002. Formula: 7.6. Storage Conditions: Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Sacituzumab govitecan (solution)
Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU-132 (solution). CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132254A.
Sacituzumab tirumotecan
Sacituzumab tirumotecan is an antibody-drug conjugate and TROP2-directed, topoisomerase I inhibitor payload-delivering agent, with a TROP2 EC50 of 2.787 ng/ml, TROP2 Ka of 0.3083 nM, and topoisomerase I IC50 of 0.7 μmol/L. Sacituzumab tirumotecan can be used for the research of metastatic triple-negative breast cancer, and metastatic non-small cell lung cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKB264; MK-2870. CAS No. 2768350-77-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164789.
SACLAC
SACLAC, a Ceramide analog, is a potent and covalent acid ceramidase (ASAH1; AC) inhibitor with a Ki of 97.1 nM. SACLAC effectively blocks AC activity and induces a decrease in sphingosine 1-phosphate (S1P) and total ceramide levels. SACLAC reduces the levels of splicing factor SF3B1 and alternative Mcl-1 mRNA splicing, increases pro-apoptotic Mcl-1S levels to induce apoptosis in acute myeloid leukemia (AML) cells. SACLAC reduces the leukemic burden in human AML xenograft mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2248703-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158783.
Saclofen
Saclofen. Group: Biochemicals. Grades: Purified. CAS No. 125464-42-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.