A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Safimaltib (JNJ-67856633) is an orally active, first-in-class, potent, selective and allosteric MALT1 protease inhibitor. Safimaltib in some cases lead to tumor stasis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-67856633. CAS No. 2230273-76-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139399.
Safinamide
Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM)[1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 μM) than at resting (IC50=262 μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FCE 26743; EMD 1195686. CAS No. 133865-89-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057.
Safinamide
Safinamide. Group: Biochemicals. Alternative Names: (S) -2- [ [4- [ (3-Fluorobenzyl) oxy] benzyl] amino] propionamide. Grades: Highly Purified. CAS No. 133865-89-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Safinamide
Safinamide (FCE-26743) is a reversible and selective monoamine oxidase B (IC50 0.098μM) inhibitor, reducing the degradation of dopamine, and a glutamate release inhibitor (IC50 8μM). It also inhibits dopamine reuptake. Safinamide also blocks sodium and calcium channels. Potential additional uses of Safinamide might be Parkinson's disease, restless leg syndrome and epilepsy. Category: Active pharmaceutical ingredients. Synonyms: FCE-26743, EMD1195686, EMD 1195686. CAS No. 133865-89-1. Product ID: API133865891. Molecular formula: C17H19FN2O2. Mole weight: 302.34.
Safinamide-[d4]
Safinamide-[d4] is the labelled analogue of safinamide. Safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: Safinamide D4. Grade: 95% by HPLC; 95% atom D. CAS No. 1147299-63-5. Molecular formula: C17H15D4FN2O2. Mole weight: 306.37.
safinamide impurity 1
safinamide impurity 1. Uses: For analytical and research use. CAS No. 690969-16-5. Molecular formula: C14H13FO2. Mole weight: 232.25. Catalog: APB690969165.
Safinamide impurity 36
Safinamide impurity 36. Uses: For analytical and research use. Alternative Names: (5S)-2-(4-((3-fluorobenzyl)oxy)phenyl)-5-methylimidazolidin-4-one. Molecular formula: C17H17FN2O2. Mole weight: 300.33. Catalog: APB01995.
Safinamide mesylate
Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 nM)[1]. Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?μM) than at resting (IC50=262?μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FCE 26743 mesylate; EMD 1195686 mesylate. CAS No. 202825-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057A.
SAFit2
SAFit2, a chemical probe, is a highly potent, highly selective FK506-binding protein 51 (FKBP51) inhibitor with a Ki of 6 nM and also enhances AKT2-AS160 binding[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1643125-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102080.
Saflufenacil
Saflufenacil is a herbicide of the pyrimidinedione chemical class preplant burndown and selective preemergence dicot weed control in multiple crops, including corn. Saflufenacil is a potent inhibitor of protoporphyrinogen IX oxidase (PPO)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 372137-35-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118923.
Saflufenacil Metabolite M800H02
Saflufenacil Metabolite M800H02. Uses: For analytical and research use. CAS No. 854122-75-1. Mole weight: 486.83. Catalog: AP854122751.
Saflufenacil Metabolite M800H11
Saflufenacil Metabolite M800H11. Uses: For analytical and research use. CAS No. 1246768-30-8. Mole weight: 472.80. Catalog: AP1246768308.
Saflufenacil Metabolite M800H35
Saflufenacil Metabolite M800H35. Uses: For analytical and research use. CAS No. 1246768-31-9. Mole weight: 352.77. Catalog: AP1246768319.
SAF-p1
SAF-p1. CAS No. 292605-65-3. Molecular formula: C140H234N36O47. Mole weight: 3173.57.
SAF-p2
SAF-p2. CAS No. 292605-66-4. Molecular formula: C138H239N41O41. Mole weight: 3128.62.
Safracin A
Safracin A is produced by the strain of Pseudomonas fluorescens A22 (IFO 14128). It has anti-gram-positive bacteria, gram-negative bacteria and anti-tumor effect. Synonyms: Y-16760; 2-Amino-N-[(1-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,7,9,10,13,14,14a,15-octahydro-5H-6,15-epiminoisoquinolino[3,2-b][3]benzazocin-9-yl)methyl]propanimidic acid. Grade: >98%. CAS No. 87578-98-1. Molecular formula: C28H36N4O6. Mole weight: 524.61.
Safracin B
Safracin B is a new antibiotic from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities. Synonyms: Antibiotic EM 5519; Antibiotic Y 16482α. Grade: ≥85% (HPLC). CAS No. 87578-99-2. Molecular formula: C28H36N4O7. Mole weight: 540.61.
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. Saframycin A also has weak activity against gram-negative bacteria and mycobacteria. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.0056 μmol/L. Synonyms: (-)-saframycin A; 21-Cyanosaframycin-B; N-[[(6S)-7α-Cyano-1,5,6,7,9,10,13,14,14aα,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6S,7R,9R,14aS,15R)-7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. Grade: 98%. CAS No. 66082-27-7. Molecular formula: C29H30N4O8. Mole weight: 562.57.
Saframycin B
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: Propanamide, N-((1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (6S-(6-alpha,9-beta,14a-alpha,15-alpha))-; N-[[(6S)-1,5,6,7,9,10,13,14,14aα,15-Decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6S,9R,14aS,15R)-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-28-8. Molecular formula: C28H31N3O8. Mole weight: 537.56.
Saframycin C
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. Synonyms: Propanamide, N-((1,5,6,7,9,10,13,14,14a,15-decahydro-2,5,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (5S-(5-alpha,6-alpha,9-beta,14a-alpha,15-alpha))-; N-[[(5S)-1,5,6,7,9,10,13,14,14aα,15-Decahydro-2,5α,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(5S,6R,9R,14aS,15R)-1,5,6,7,9,10,13,14,14a,15-decahydro-2,5,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-29-9. Molecular formula: C29H33N3O9. Mole weight: 567.59.
Saframycin D
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: N-[[(6R)-6,7,9,10,13,14,14aα,15-Octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6R,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-((6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (6R-(6-alpha,9-beta,14a-alpha,15-alpha))-. CAS No. 66082-30-2. Molecular formula: C28H31N3O9. Mole weight: 553.56.
Saframycin E
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: Propanamide, N-[[(5S,6R,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4,5-trihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-31-3. Molecular formula: C28H33N3O9. Mole weight: 555.58.
Saframycin F
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.59 μmol/L. Synonyms: 21-Cyanosaframycin D; N-[[(6R)-7α-Cyano-6,7,9,10,13,14,14aα,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6R,7R,9R,14aS,15R)-7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-[(7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-oxo-, [6R-(6a,7a,9b,14aa,15a)]-; (+)-Saframycin F. CAS No. 92569-03-4. Molecular formula: C29H30N4O9. Mole weight: 578.57.
Saframycin G
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.03 μmol/L. Synonyms: 14-Hydroxysaframycin A; Propanamide, N-[[(5S,6R,7R,9R,14aS,15R)-7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-[(7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-oxo-, [5S-(5a,6a,7a,9b,14aa,15a)]-; (-)-Saframycin G; Propanamide, N-((7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1-4-10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (5S-(5alpha,6alpha,7alpha,9beta,14aalpha,15alpha))-. CAS No. 92569-02-3. Molecular formula: C29H30N4O9. Mole weight: 578.57.
Saframycin H
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.033 μmol/L. Synonyms: 25-Dihydro-25-beta-ketopropylsaframycin A; Pentanamide, N-[(7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-hydroxy-2-methyl-4-oxo-, (1R,2S,10R,13S)-. CAS No. 92569-01-2. Molecular formula: C32H36N4O9. Mole weight: 620.65.
Saframycin Mx1
It is produced by the strain of Myxococcus xanthus. It has anti-gram-positive bacteria and gram-negative bacteria effects. Synonyms: Saframycin Mx-1; Propanamide, 2-amino-N-((6,7,9,10,13,14,14a,15-octahydro-1,4,7-trihydroxy-2,5,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-, (5S-(5-alpha,6-beta,7-alpha,9-beta(R*),14a-alpha,15-beta))-; 2-Amino-N-[[[(5S)-6,7,9,10,13,14,14aα,15-octahydro-1,4,7α-trihydroxy-2,5α,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin]-9β-yl]methyl]propionamide; Propanamide, 2-amino-N-[[(5S,6S,7S,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4,7-trihydroxy-2,5,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-, (2S)-. CAS No. 113036-78-5. Molecular formula: C29H38N4O9. Mole weight: 586.63.
Saframycin Mx2
It is produced by the strain of Myxococcus xanthus. It has anti-gram-positive bacteria and gram-negative bacteria effects. Synonyms: (S)-2-Amino-N-[[[(5S)-6,7,9,10,13,14,14aα,15-octahydro-1,4-dihydroxy-2,5α,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin]-9β-yl]methyl]propionamide; Saframycin Mx-2; Propanamide, 2-amino-N-[[(5S,6R,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,5,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-, (2S)-; Propanamide, 2-amino-N-[(6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,5,11-trimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-, [5S-[5a,6a,9b(R*),14aa,15a]]-. CAS No. 113036-79-6. Molecular formula: C29H38N4O8. Mole weight: 570.63.
Safranal
Safranal is an orally active main component of Saffron (Crocus sativus) and is responsible for the unique aroma of this spice. Safranal has neuroprotective and anti-inflammatory effects and has the potential for Parkinsons disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 116-26-7. Pack Sizes: 500 mg. Product ID: HY-N7560.
Safranal. CAS No. 116-26-7. FEMA No. 3389. Kosher: Y. VIGON Item # 500930. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers.
America & Internationally
Safranine O (C.I. 50240)
25g Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators. Formula: C20H19ClN4. CAS No. 477-73-6. Prepack ID 42186946-25g. Molecular Weight 350.84. See USA prepack pricing.
Safrole
Safrole, is an oily liquid typically extracted from the root-bark or the fruit of sassafras plants in the form of sassafras oil. It is a precursor in the synthesis of the insecticide synergist piperonyl butoxide and the empathogenic / entactogenic drug MDMA (M303985). Group: Biochemicals. Grades: Highly Purified. CAS No. 94-59-7. Pack Sizes: 10mg, 25 mg. Molecular Formula: C10H10O2. US Biological Life Sciences.
Worldwide
Safusidenib
Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective mutant IDH1 inhibitor. Safusidenib strongly inhibits mutant IDH1 but not wild-type IDH1. Safusidenib impairs tumor activity in chondrosarcoma[1]. Safusidenib exhibits activity against IDH1R132H, and IDH1R132C with IC50s of 15, and 130 nM in assays without any preincubation, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AB-291; DS-1001. CAS No. 1898206-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145594.
SAG
A potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15. Group: Biochemicals. Grades: Highly Purified. CAS No. 912545-86-9. Pack Sizes: 1mg. Molecular Formula: C??H??ClN?OS. US Biological Life Sciences.
Worldwide
SAG
SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 912545-86-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12848.
SAG-524
SAG-524 is a potent oral small molecule HBV viral replication inhibitor. SAG-524 decreased HBV-DNA and HbsAg levels in supernatant of HepG2.2.15 cells, IC50 0.92 and 1.4 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2246696-89-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157993.
SAG dihydrochloride
SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2702366-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12848C.
Sage Extract
Sage Extract. Applications: Used for women skin health care products, beauty products. Group: Others. Synonyms: Sage Extract; Salvia officinalis Linn. Purity: 10:1 By TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Whole herb. Species: Salvia officinalis Linn. Sage Extract; Salvia officinalis Linn; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-090.
Sage Ground Powder
Sage Ground Powder.
CA, FL & NJ
Sage Leaf Powder
Sage Leaf Powder.
CA, FL & NJ
Sageone
Sageone is extracted from the roots of Salvia miltiorrhiza. It has antiviral activity. Synonyms: 2,3,9,10-Tetrahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-4(1H)-phenanthrenone; 4(1H)-Phenanthrenone, 2,3,9,10-tetrahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-. Grade: 97.0%. CAS No. 142546-15-4. Molecular formula: C19H24O3. Mole weight: 300.398.
SAG hydrochloride
SAG hydrochloride is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG hydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095432-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12848B.
SAG (Smoothened Agonist)
SAG (Smoothened Agonist) is a potent agonist of Smoothened (Smo). Smoothened Agonist induces firefly luciferase expression in Shh-LIGHT2 cells with an EC50 of 3 nM. Group: Inhibitors. CAS No. 912545-86-9. Pack Sizes: 5mg. Product ID: S6384. Formula: C28H28ClN3OS. Smiles: CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(Cl)C5=CC=CC=C5S4. Storage Conditions: 3 years -20°C powder.
United States; Europe
SAG (Smoothened Agonist) Hydrochloride
SAG (Smoothened Agonist) HCl is a cell-permeable Smoothened (Smo) agonist with EC50 of 3 nM in Shh-LIGHT2 cells. Group: Inhibitors. CAS No. 2095432-58-7. Pack Sizes: 2mg. Product ID: S7779. Formula: C28H29Cl2N3OS. Smiles: CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
SAG (Standard)
SAG (Standard) is the analytical standard of SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 912545-86-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12848R.
SAH
SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAH (S-Adenosylhomocysteine). CAS No. 979-92-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19528.
SAHA-BPyne
SAHA-BPyne is an activity-based protein profiling (ABPP) probe for detecting HDAC activity, which covalently labels the proximal proteins through a photoactivation. SAHA-BPyne inhibits HDAC activity in HeLa nuclear lysate with an IC50 of less than 5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 930772-88-6. Pack Sizes: 100 μg (1.05 mM * 200 μL in Methanol); 1 mg (1.05 mM * 2 mL in Methanol). Product ID: HY-126943.
SAHA chloroalkane T1
SAHA chloroalkane T1 is a chloroalkane capture tag by tethering Vorinostat (SAHA) and a chloroalkane tag T1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1613617-05-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111595.
SAHM1
SAHM1, a peptide mimetic of a dominant negative form of mastermind-like (MAML), inhibits canonical Notch transcription complex formation. SAHM1 can be used for the research of allergic airway inflammation in mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2050906-89-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2203.
SAH-SOS1A
SAH-SOS1A is a cell-permeable, stabilized hydrocarbon-stapled alpha helical peptide that acts as a K-Ras/son of sevenless 1 (SOS1) interaction inhibitor. It binds within nucleotide binding pocket of wild-type and mutant K-Ras. CAS No. 1652561-87-9. Molecular formula: C100H159N27O28. Mole weight: 2187.53.
SAH (Standard)
SAH (Standard) is the analytical standard of SAH. This product is intended for research and analytical applications. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAH (S-Adenosylhomocysteine) (Standard). CAS No. 979-92-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19528R.
SAICAR
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3031-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126585.
Saikosaponin A
Saikosaponin A. Group: Biochemicals. CAS No. 20736-09-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Saikosaponin A
Saikosaponin A. Group: Biochemicals. Grades: Plant Grade. CAS No. 20736-09-8. Pack Sizes: 20mg. Molecular Formula: C42H68O13, Molecular Weight: 780.98. US Biological Life Sciences.
Worldwide
Saikosaponin A
10mg Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C42H68O13. CAS No. 20736-09-8. Prepack ID 23951126-10mg. Molecular Weight 780.98. See USA prepack pricing.
Saikosaponin A
Saikosaponin A, a triterpenoid glycoside, induces apoptotic mechansims in human breast cancer cell lines. It also displays an inhibitory activity against allergic asthma. It mediates the inflammatory response by inhibiting the MAPK and NF-κB pathways in LPS-stimulated RAW 264.7 cells. It as antioxidants improve antioxidant status. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (3b,4a,16b)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 3-O-b-D-glucopyranosyl-b-D-fucoside; (3β,4α,16β)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside; Salikosaponin A. Grade: >98%. CAS No. 20736-09-8. Molecular formula: C42H68O13. Mole weight: 780.98.
Saikosaponin A
Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also serve as a potential peroxisome proliferator-activated receptor γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20736-09-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0246.
Saikosaponin B1
Saikosaponin B1 is extracted from the herb of Bupleurum chinense DC. It potently stimulated PGE2 release. Synonyms: (3b,4a,16b)-16,23,28-trihydroxyoleana-11,13(18)-dien-3-yl-6-deoxy-3-o-beta-d-glucopyranosyl-beta-d-galactopyranoside; [(4R)-16β,23,28-Trihydroxyoleana-11,13(18)-dien-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside. Grade: >98%. CAS No. 58558-08-0. Molecular formula: C42H68O13.
Saikosaponin B1
Saikosaponin B1. Group: Biochemicals. Grades: Plant Grade. CAS No. 58558-08-0. Pack Sizes: 10mg. Molecular Formula: C42H68O13, Molecular Weight: 780.98. US Biological Life Sciences.
Worldwide
Saikosaponin B2
Saikosaponin B2. Group: Biochemicals. Grades: Plant Grade. CAS No. 58316-41-9. Pack Sizes: 10mg. Molecular Formula: C42H68O13, Molecular Weight: 780.98. US Biological Life Sciences.
Worldwide
Saikosaponin B2
5mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C42H68O13. CAS No. 58316-41-9. Prepack ID 90028056-5mg. Molecular Weight 780.98. See USA prepack pricing.
Saikosaponin B2
Saikosaponin B2 is extracted from the herb of Bupleurum chinense DC. It acted on HCV E2. It inhibited infection by several genotypic strains and prevented binding of serum-derived HCV onto hepatoma cells. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: (3b,4a,16a)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl 3-O-b-D-glucopyranosyl-b-D-fucoside; (3β,4α,16α)-16,23,28-Trihydroxyoleana-11,13(18)-dien-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside. Grade: >98%. CAS No. 58316-41-9. Molecular formula: C42H68O13. Mole weight: 780.98.
Saikosaponin B3
Saikosaponin B3, a triterpene glycoside, is a saikosaponin isolated from Bupleurum chinese DC. Bupleurum chinese DC, also called as Bupleuri Radix, is one of the most important crude drugs used inmany traditional Chinesemedicines. And it is believed that saikosaponins are responsible for part of the pharmaceutical properties of Bupleuri Radix. Synonyms: β-D-Galactopyranoside, (3β,?4α,?11α,?16β)?-16,?23,?28-trihydroxy-11-methoxyolean-12-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-; (3β,4α,11α,16β)-16,23,28-Trihydroxy-11-methoxyolean-12-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside; Oleanane, β-D-galactopyranoside deriv. Grade: > 98%. CAS No. 58316-42-0. Molecular formula: C43H72O14. Mole weight: 813.02.
Saikosaponin B4
5mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C43H72O14. CAS No. 58558-09-1. Prepack ID 90028058-5mg. Molecular Weight 813.02. See USA prepack pricing.
Saikosaponin C
Saikosaponin C is extracted from the root of Bupleurum chinense DC. It efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation. It exhibits anti-HBV activity. It may have the potential for therapeutic angiogenesis but is not suitable for cancer therapy. Synonyms: (3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-4)-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranoside; [13,28-Epoxy-16β-hydroxyolean-11-en-3β-yl] 4-O-(6-deoxy-α-L-mannopyranosyl)-6-O-(β-D-glucopyranosyl)-β-D-glucopyranoside; (3β,16β)-13,28-Epoxy-16-hydroxyolean-11-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside; Cyclosaponin C. Grade: >98%. CAS No. 20736-08-7. Molecular formula: C48H78O17. Mole weight: 927.12.
Saikosaponin C
5mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C48H72O17. CAS No. 20736-08-7. Prepack ID 90027192-5mg. Molecular Weight 921.08. See USA prepack pricing.
Saikosaponin C
Saikosaponin C is an orally active MMP-2 inducer. Saikosaponin C induces the survival, growth, migration and capillary tube formation of endothelial cells. Saikosaponin C inhibits the early stage of hepatitis C virus infection. Saikosaponin C can be used in research related to ischemic tissue diseases, chronic kidney diseases and hepatitis C virus infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20736-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0249.
Saikosaponin C
Saikosaponin C. Group: Biochemicals. Grades: Plant Grade. CAS No. 20736-08-7. Pack Sizes: 20mg. Molecular Formula: C48H78O17, Molecular Weight: 927.12. US Biological Life Sciences.
Worldwide
Saikosaponin D
Saikosaponin D. Group: Biochemicals. Grades: Plant Grade. CAS No. 20874-52-6. Pack Sizes: 20mg. Molecular Formula: C42H68O13, Molecular Weight: 780.98. US Biological Life Sciences.