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| Product | Description | |
|---|---|---|
| Sacubitril impurity 8 | Sacubitril impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 766480-48-2. Molecular Formula: C24H29NO5. Mole Weight: 411.5. Catalog: APB766480482. |  |
| Sacubitril impurity 9 | Sacubitril impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149709-63-7. Molecular Formula: C24H29NO5. Mole Weight: 411.5. Catalog: APB149709637. | |
| Sacubitril N-Boc Ester | Sacubitril N-Boc Ester is an impurity of Sacubitril, an endopeptidase inhibitor that is effective in the treatment of hypertension and heart failure. Synonyms: Ethyl (2R, 4S) -5- (4-biphenylyl) -2-methyl-4- ({[ (2-methyl-2-propanyl) oxy]carbonyl}amino) pentanoate; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-Biphenyl]-4-pentanoic Acid Ethyl Ester; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-methyl-, ethyl ester, (alphaR,gammaS)-; Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-4-[(tert-butoxycarbonyl)amino]-2-methylbutanoate. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.53. |  |
| Sacubitril sodium | Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC 50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHU-377 sodium. CAS No. 149690-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407B. |  |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Synonyms: sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696. CAS No. 149690-05-1. Molecular formula: C24H29NO5.Na. Mole weight: 434.47. | |
| Sacubitril/Valsartan | Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure [1] [2] [3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCZ696. CAS No. 936623-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18204A. | |
| S-Ademetionine | S-Ademetionine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine, 1,4-butanedisulfonate, 1,4-butanedisulfonate (2:2:1). CAS No. 101020-79-5. Molecular Formula: C15H23N6O5S·C4H10O6S2·1/2C4H8O6S2. Mole Weight: 1451.62. Catalog: APB101020795. | |
| s-Adenosyl-1,12-diamino-3-thio-9-azadodecane | Heterocyclic Organic Compound. CAS No. 118436-57-0. Catalog: ACM118436570. |  |
| S-Adenosyl-DL-methionine | S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine [1]. Uses: Scientific research. Group: Natural products. CAS No. 17176-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-126126. | |
| S-Adenosyl-Homocysteine | S-Adenosyl-homocysteine hydrolyzes in acid solution (0.1M HCl, 100°C, over 90 minutes) to form S-ribosylhomocysteine. It is not hydrolyzed in neutral alkaline solutions (stable in 0.1M NaOH at 25°C over 10 minutes), but oxidation is more rapid in alkaline solution. S-Adenosyl-homocysteine is slowly oxidized to the sulfoxide as a solid and in solution. It is protected from oxidation by thiodiglycol; neutral solutions containing thiodiglycol are stable for long periods at 25°C. Group: Biochemicals. Grades: Highly Purified. CAS No. 979-92-0. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| S-adenosylhomocysteine deaminase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. Group: Enzymes. Synonyms: adenosylhomocysteine deaminase. Enzyme Commission Number: EC 3.5.4.28. CAS No. 125149-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4555; S-adenosylhomocysteine deaminase; EC 3.5.4.28; 125149-24-8; adenosylhomocysteine deaminase. Cat No: EXWM-4555. |  |
| S-ADENOSYL-L-CYSTEINE | Cas No. 35899-53-7. Molecular formula: C13H18N6O5S. Mole weight: 370.38. | |
| s-Adenosyl-L-ethionine iodide | Heterocyclic Organic Compound. CAS No. 102029-72-1. Catalog: ACM102029721. | |
| S-adenosyl-L-homocysteine | S-adenosyl-L-homocysteine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)butanoic acid. CAS No. 979-92-0. Molecular Formula: C14H20N6O5S. Mole Weight: 384.41. Catalog: APB979920. | |
| S-Adenosyl-L-Homocysteine Hydrolase, Recombinant | Enzyme in vertebrates which catabolizes S-adenosyl-L-homocysteine. S-adenosyl-l-homocysteine hydrolase (sahh, ec 3.3.1.1) (adohcyase) is an enzyme of the activated methyl cycle, responsible for the reversible hydration of s-adenosyl-l-homocysteine into adenosine and homocysteine. sahh is a ubiquitous enzyme which binds and requires nad+ as a cofactor. adohcyase is a highly conserved protein of about 430 to 470 amino acids. the family contains a glycine-rich region in the central part of adohcyase; aregion thought to be involved in nad-binding. this protein may use themorpheein model of allosteric regulation. Group: Enzymes. Synonyms: Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocyste. Enzyme Commission Number: EC 3.3.1.1. Purity: >90% (SDS-PAGE test). Mole weight: About 44kDa (SDS-PAGE detection). Activity: 140U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 20% glycerol, 4°C, store at -20°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. Adenosylhomocysteinase; EC 3.3.1.1; S-adenosylhomocysteine synthase; S-adenosylhomocysteine hydrolase; adenosylhomocysteine hydrolase (ambiguous); S-adenosylhomocysteinase; SAHase; AdoHcyase; 9025-54-1. Cat No: NATE-1150. | |
| S-Adenosyl-L-methionine | S-Adenosyl-L-methionine. Group: Biochemicals. Alternative Names: SAMe. Grades: Highly Purified. CAS No. 29908-03-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C15H22N6O5S, Molecular Weight: 398.44. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-Methionine | S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-adenosylmethionine. Heptral; Gumbaral. S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet; (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate. Grades: 98%. CAS No. 29908-03-0. Molecular formula: C15H22N6O5S. Mole weight: 398.438. | |
| S-Adenosyl-L-methionine chloride dihydrochloride | S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is a methyl donor and cofactor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride. CAS No. 86867-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-14614A. | |
| S-Adenosyl-L-methionine Disulfate Tosylate (doMet SAM Disulfate p-toluenesulfonate, SAMe) | A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. SAM is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 97540-22-2. Pack Sizes: 50g, 100g, 250g, 500g. Molecular Formula: C??H??N?O??S?, Molecular Weight: 766.8. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-methionine p-toluenesulfonate | S-(5?-Adenosyl)-L-methionine (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma (HCC), HepG2 cells and colon cancer cells. Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury. Group: Biochemicals. Alternative Names: (3S) -5'-[ (3-Amino-3-carboxylatopropyl) methylsulphonio]-5'-deoxyadenosine) ; SAMe p-toluenesulfonate; S-Adenosylmethionine Tosylate; Adomet; Ademetionine. Grades: Highly Purified. CAS No. 17176-17-9. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| S-Adenosyl-L-methionine p-toluenesulfonate | S-Adenosyl-L-methionine p-toluenesulfonate, a vital compound harnessed within the biomedical sector, assumes a pivotal position as a cofactor amidst the intricate processes involved in neurotransmitter, DNA, and protein synthesis. Predominantly employed to address myriad liver afflictions such as chronic liver disease and cholestasis, this product's therapeutic efficacy extends to mood disorders by fostering regulation of neurotransmitter equilibrium, specifically targeting depression. Synonyms: S-(5'-Adenosyl)-L-methionine tosylate; Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, 4-methylbenzenesulfonate (1:1); Adenosine, 5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, (3S)-, 4-methylbenzenesulfonate (salt); Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, salt with 4-methylbenzenesulfonic acid (1:1); S-Adenosylmethionine toluene-p-sulfonate; S-Adenosylmethionine tosylate; SAMe p-toluenesulfonate. Grades: 95%. CAS No. 52248-03-0. Molecular formula: C15H23N6O5S.C7H7O3S. Mole weight: 570.64. | |
| S-Adenosyl-L-methionine tosylate | S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Adenosyl methionine tosylate; Ademetionine tosylate; AdoMet tosylate. CAS No. 52248-03-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0617A. | |
| S-Adenosylmethione-1,4-butanedisulfonate | Ademethionine 1,4-Butanedisulfonate is used in the synthesis of sulfonio-adenosyl-L-methionine (SAMe) salts. Group: Biochemicals. Grades: Highly Purified. CAS No. 101020-79-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C19H33N6O11S3. 1/2(C4H8O6S2), Molecular Weight: 1451.63. US Biological Life Sciences. | Worldwide |
| S-Adenosy-L-methionine disulfate p-toluenesulfonate (SAMe) | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Building Blocks, Organics. Formula: C22H34N6O16S4. CAS No. 97540-22-2. Prepack ID 90005691-1g. Molecular Weight 766.8. See USA prepack pricing. |  |
| S-adenosylmethionine synthetase, Recombinant | S-adenosylmethionine synthetase (EC 2.5.1.6) (also known as methionine adenosyltransferase (MAT)) is an enzyme that creates S-adenosylmethionine (AdoMet) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy). AdoMet is a methyl donor for transmethylation. It gives away its methyl group and is also the propylamino donor in polyamine biosynthesis. S-adenosylmethionine synthetasecan be considered the rate-limiting step of the methionine cycle. S-adenosylmethionine (sam) is a methyl donor and allows dna methylation. once dna is methylated, it switches the genes off and therefore, s-adenosylmethionine can be considered tocontrol gene expressi...denosylmethioninesynthase isoform type-1; AdoMet synthase 1; MAT 1; Methionineadenosyltransferase I/III; MAT-I/III; MAT1A; AMS1. Enzyme Commission Number: EC 2.5.1.6. Purity: >90% (SDS-PAGE test). Mole weight: About 46kDa (SDS-PAGE detection). Activity: >700U/mg. Appearance: White powder, lyophilized. Storage: Redissolved in 30% glycerol, 4°C, store at -20°C/-80°C for long-term preservation, Avoid multiple freeze-thaw cycles. Form: Freeze dried powder. EC 2.5.1.6; MAT; MATA1; SAMS; SAMS1; Methionine adenosyltransferase 1; S-adenosylmethioninesynthase isoform type-1; AdoMet synthase 1; MAT 1; Methionineadenosyltransferase I/III; MAT-I/III; MAT1A; AMS1. Cat No: NATE-1151. | |
| S-adenosylmethionine:tRNA ribosyltransferase-isomerase | The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. It is part of the queuosine biosynthesis pathway. Group: Enzymes. Synonyms: QueA enzyme; queuosine biosynthesis protein QueA. Enzyme Commission Number: EC 2.4.99.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2701; S-adenosylmethionine:tRNA ribosyltransferase-isomerase; EC 2.4.99.17; QueA enzyme; queuosine biosynthesis protein QueA. Cat No: EXWM-2701. | |
| SAE-14 | SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC 50 value of 28.5 nM, can antagonize 7α, 25-OHC - induced calcium mobilization with IC 50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GPR183 antagonist-1. CAS No. 1241280-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147222. | |
| Saenta | Heterocyclic Organic Compound. Alternative Names: 5'-S-(2-Aminoethyl)-N6-[(4-nitrobenzyl)-5'-thioadenosine; 5'-S-(2-Aminoethyl)-N-[(4-nitrophenyl)methyl]-5'-thio-adenosine. CAS No. 130117-76-9. Molecular formula: C19H23N7O5S. Mole weight: 461.5. Purity: 0.96. IUPACName: (2S,3S,4R,5R)-2-(2-aminoethylsulfanylmethyl)-5-[6-[(4-nitrophenyl)methylamino]purin-9-yl]oxolane-3,4-diol. Canonical SMILES: C1=CC (=CC=C1CNC2=NC=NC3=C2N=CN3C4C (C (C (O4)CSCCN)O)O)[N+] (=O)[O-]. Density: 1.7g/cm³. Catalog: ACM130117769. | |
| SAENTA | A novel ligand with high affinity for polypeptides associated with nucleoside transport. Uses: A novel ligand with high affinity for polypeptides associated with nucleoside transport. Synonyms: 5'-S-(2-Aminoethyl)-N6-[(4-nitrobenzyl)-5'-thioadenosine; 5'-S-(2-Aminoethyl)-N-[(4-nitrophenyl)methyl]-5'-thio-adenosine. Grades: 96%. CAS No. 130117-76-9. Molecular formula: C19H23N7O5S. Mole weight: 461.5. | |
| SAENTA | SAENTA. Group: Biochemicals. Alternative Names: 5-S-(2-Aminoethyl)-N6-[(4-nitrobenzyl)-5-thioadenosine; 5'-S-(2-Aminoethyl)-N-[(4-nitrophenyl)methyl]-5'-thio-adenosine. Grades: Highly Purified. CAS No. 130117-76-9. Pack Sizes: 5mg. Molecular Formula: C19H23N7O5S, Molecular Weight: 461.5. US Biological Life Sciences. | Worldwide |
| Safed Musli P.E. 50% Saponins Gravimetry | Safed Musli P.E. 50% Saponins Gravimetry. |  CA, FL & NJ |
| Safety & Spill Equipment |  | |
| Safflomin A (Hydroxysafflor yellow A) | Safflomin A (Hydroxysafflor yellow A). Group: Biochemicals. Alternative Names: Hydroxysafflor yellow A. Grades: Plant Grade. CAS No. 78281-02-4. Pack Sizes: 20mg. Molecular Formula: C27H32O16, Molecular Weight: 612.533. US Biological Life Sciences. | Worldwide |
| Safflor Yellow A | Safflor Yellow A is an exquisite natural constituent deriving from the revered Carthamus tinctorius floraboasting exceptional prowess in studying deleterious inflammatory cascades in ameliorating a plethora of maladies, such as cardiac afflictions, neoplasms and hepatic impairments. CAS No. 85532-77-0. Molecular formula: C27H30O15. Mole weight: 594.52. | |
| Saffloweramidopropyl ethyldimonium ethosulfate | Emulsifying agent. Group: Oil field. Alternative Names: 1-Propanaminium, N-ethyl-N,N-dimethyl-3-amino-, N-safflower acyl derivs., ethyl sulfates. CAS No. 113492-04-9. Catalog: ACM113492049. | |
| Safflower Extract | Safflower Extract. Applications: Natural color for use in beverage, ice-cream, food, medicine and cosmetics industries. Group: Others. Synonyms: Safflower Extract; Carthamus tinctorius L. Purity: 2%-4% Carthamin by HPLC, 5-10:1 by TLC. Appearance: Yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Flower. Species: Carthamus tinctorius L. Safflower Extract; Carthamus tinctorius L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-117. | |
| Safflower seed oil microencapsulated powder | Safflower seed oil microencapsulated powder. Product ID: CDF4-0208. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0208; Safflower seed oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: safflower seed. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| Saffron C.I. 75100 | Saffron C.I. 75100. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Saffron Extract | Saffron Extract. Applications: Natural color for use in food , supplement, cosmetics and pharmaceutical industries. Group: Others. Synonyms: Saffron Extract; 84604-17-1; Crocus sativus L. CAS No. 84604-17-1. Purity: 0.3% Saffranol By HPLC. Appearance: Yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Crocus sativus L. Saffron Extract; 84604-17-1; Crocus sativus L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-114. | |
| Saffron Flower P.E. 4:1 | Saffron Flower P.E. 4:1. | CA, FL & NJ |
| Saffron P.E. 0.2% Safranal HPLC | Saffron P.E. 0.2% Safranal HPLC. | CA, FL & NJ |
| Safinamide | Safinamide, a selective MAO-B inhibitor, could be effective against Parkinson's disease for patients mid-to-late-stage. IC50: 98 nM. Uses: Safinamide is a selective mao-b inhibitor that could be effective against parkinson's disease for patients mid-to-late-stage. Synonyms: SAFINAMIDE: (S) - (+) -2-[4- (3-FLUOROBENZYLOXY) BENZYLAMINO]PROPANAMIDE METHANSULFONATE;FCE 26743; Safinamide; 2 (S) -[4- (3-Fluorobenzyloxy) benzylamino]propionamide. Grades: 97%. CAS No. 133865-89-1. Molecular formula: C17H19FN2O2. Mole weight: 302.34. | |
| Safinamide | Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 μM) [1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 26743; EMD 1195686. CAS No. 133865-89-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057. | |
| Safinamide | Safinamide. Group: Biochemicals. Alternative Names: (S) -2- [ [4- [ (3-Fluorobenzyl) oxy] benzyl] amino] propionamide. Grades: Highly Purified. CAS No. 133865-89-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Safinamide (Hydrochloride) | Safinamide (Hydrochloride). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride. CAS No. 29110-48-3. Molecular Formula: C9H9Cl2N3O·HCl. Mole Weight: 282.55. Catalog: APB29110483. | |
| safinamide impurity 1 | safinamide impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 690969-16-5. Molecular Formula: C14H13FO2. Mole Weight: 232.25. Catalog: APB690969165. | |
| Safinamide Impurity 1 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: (S) -2- ( (3- (3-fluorobenzyl) -4- ( (3-fluorobenzyl) oxy) benzyl) amino) propanamide - See more at: https://www. clearsynth. com/en/CSP01140. html#sthash. mrupusLk. dpuf. Grades: > 95%. CAS No. 1000370-27-3. Molecular formula: C24H24F2N2O2. Mole weight: 410.47. | |
| Safinamide Impurity 2 | Safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: 3-(3-Fluorobenzyl)-4-((3-fluorobenzyl)oxy)benzaldehyde. Grades: > 95%. CAS No. 1000370-24-0. Molecular formula: C21H16F2O2. Mole weight: 338.36. | |
| Safinamide Impurity 3 | Safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Grades: > 95%. Molecular formula: C17H19FN2O2. Mole weight: 302.35. | |
| Safinamide impurity 36 | Safinamide impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (5S)-2-(4-((3-fluorobenzyl)oxy)phenyl)-5-methylimidazolidin-4-one. Molecular Formula: C17H17FN2O2. Mole Weight: 300.33. Catalog: APB01995. | |
| Safinamide Impurity 5 | An impurity of Safinamide, a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: (S) -2- ( (4- ( (3-Fluorobenzyl) oxy) benzyl) amino) propanoic acid; (2S) -2-[[4-[ (3-fluorophenyl) methoxy]phenyl]methylamino]propanoic acid. Grades: >95%. CAS No. 1160513-60-9. Molecular formula: C17H18FNO3. Mole weight: 303.34. | |
| Safinamide Impurity 6 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Grades: > 95%. Molecular formula: C17H19FN2O3. Mole weight: 318.35. | |
| Safinamide Impurity 7 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Grades: > 95%. Molecular formula: C17H17FN2O3. Mole weight: 316.34. | |
| Safinamide Impurity 8 | An impurity of safinamide,safinamide is a selective monoamine oxidase B inhibitor, reducing degradation of dopamine. Synonyms: 4-[(3-Fluorophenyl)methoxy]benzenemethanol. Grades: > 95%. CAS No. 690969-16-5. Molecular formula: C14H13FO2. Mole weight: 232.26. | |
| Safinamide mesylate | Safinamide is a highly selective MAO-B inhibitor in rat brain mitochondria, with an IC50 of 98 nM. safinamide inhibits MAO-B in human brain with an IC50 of 9 nM. Synonyms: PNU-151774E; (S) -2- ( (4- ( (3-Fluorobenzyl) oxy) benzyl) amino) propanamide methanesulfonate. Grades: >98%. CAS No. 202825-46-5. Molecular formula: C17H19FN2O2.CH4O3S. Mole weight: 398.45. | |
| Safinamide mesylate | Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 μM) over MAO-A (IC 50 =580 nM) [1]. Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8 μM) than at resting ( IC 50 =262 μM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE 26743 mesylate; EMD 1195686 mesylate. CAS No. 202825-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70057A. | |
| Safingol | Safingol is a lyso-sphingolipid protein kinase C (PKC) inhibitor. It binds to and inhibits the regulatory phorbol-binding domain of PKC. It has the potential for the treatment of solid tumors. Synonyms: L-threo-Dihydrosphingosine; L-threo-Sphinganine; L-threo-2-Amino-1,3-octadecanediol; (2S,3S)-2-aminooctadecane-1,3-diol. Grades: ≥98%. CAS No. 15639-50-6. Molecular formula: C18H39NO2. Mole weight: 301.51. | |
| SAfit2 | SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51). SAfit2 has been studied as a potential therapeutic agent for the treatment of major depression, obesity and chronic pain. Synonyms: [(1R)-3-(3,4-dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2S)-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate. Grades: ≥95%. CAS No. 1643125-33-0. Molecular formula: C46H62N2O10. Mole weight: 802.99. | |
| Safotibant | Safotibant is a non-peptide bradykinin B1 receptor antagonis. It is used for the topical treatment of diabetic macular oedema. It displayed binding Ki values of 0.35 and 6.5 nM at cloned human and mouse B1 receptors respectively. It also reversed acute inflammatory pain induced by carrageenan, and persistent inflammatory pain induced by CFA. It was developed by Sanofi and was in clinic phase 2 trials, but now it is terminated. Uses: Safotibant is used for the topical treatment of diabetic macular oedema. Synonyms: N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[(4-methoxy-2,6-dimethylphenyl)sulfonyl-methylamino]ethoxy]-N-methylacetamide;LF-22-0542; LF22-0542; LF 22-0542; LF-220542; LF220542; LF 220542; Safotibant. Grades: 98%. CAS No. 633698-99-4. Molecular formula: C25H34N4O5S. Mole weight: 502.63. | |
| Safracin A | Safracin A is produced by the strain of Pseudomonas fluorescens A22 (IFO 14128). It has anti-gram-positive bacteria, gram-negative bacteria and anti-tumor effect. Synonyms: Y-16760; 2-Amino-N-[(1-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,7,9,10,13,14,14a,15-octahydro-5H-6,15-epiminoisoquinolino[3,2-b][3]benzazocin-9-yl)methyl]propanimidic acid. Grades: >98%. CAS No. 87578-98-1. Molecular formula: C28H36N4O6. Mole weight: 524.61. | |
| Safracin B | Safracin B is a new antibiotic from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities. Synonyms: Antibiotic EM 5519; Antibiotic Y 16482&alpha. Grades: ≥85% (HPLC). CAS No. 87578-99-2. Molecular formula: C28H36N4O7. Mole weight: 540.61. | |
| Safraleine ® | Safraleine ®. CAS No. 54440-17-4. FEMA No. 4556. Kosher: Y. VIGON Item # 503031. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, saffron indenone. |  America & Internationally |
| Saframycin A | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. Saframycin A also has weak activity against gram-negative bacteria and mycobacteria. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.0056 μmol/L. Synonyms: (-)-saframycin A; 21-Cyanosaframycin-B; N-[[(6S)-7α-Cyano-1,5,6,7,9,10,13,14,14aα,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6S,7R,9R,14aS,15R)-7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. Grades: 98%. CAS No. 66082-27-7. Molecular formula: C29H30N4O8. Mole weight: 562.57. | |
| Saframycin B | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: Propanamide, N-((1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (6S-(6-alpha,9-beta,14a-alpha,15-alpha))-; N-[[(6S)-1,5,6,7,9,10,13,14,14aα,15-Decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6S,9R,14aS,15R)-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-28-8. Molecular formula: C28H31N3O8. Mole weight: 537.56. | |
| Saframycin C | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. Synonyms: Propanamide, N-((1,5,6,7,9,10,13,14,14a,15-decahydro-2,5,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (5S-(5-alpha,6-alpha,9-beta,14a-alpha,15-alpha))-; N-[[(5S)-1,5,6,7,9,10,13,14,14aα,15-Decahydro-2,5α,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6α,15α-epimino-4H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(5S,6R,9R,14aS,15R)-1,5,6,7,9,10,13,14,14a,15-decahydro-2,5,11-trimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-29-9. Molecular formula: C29H33N3O9. Mole weight: 567.59. | |
| Saframycin D | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: N-[[(6R)-6,7,9,10,13,14,14aα,15-Octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6R,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-((6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (6R-(6-alpha,9-beta,14a-alpha,15-alpha))-. CAS No. 66082-30-2. Molecular formula: C28H31N3O9. Mole weight: 553.56. | |
| Saframycin E | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It also has weak activity against mycobacteria. Synonyms: Propanamide, N-[[(5S,6R,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,4,5-trihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-. CAS No. 66082-31-3. Molecular formula: C28H33N3O9. Mole weight: 555.58. | |
| Saframycin F | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.59 μmol/L. Synonyms: 21-Cyanosaframycin D; N-[[(6R)-7α-Cyano-6,7,9,10,13,14,14aα,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6R,7R,9R,14aS,15R)-7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-[(7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-oxo-, [6R-(6a,7a,9b,14aa,15a)]-; (+)-Saframycin F. CAS No. 92569-03-4. Molecular formula: C29H30N4O9. Mole weight: 578.57. | |
| Saframycin G | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.03 μmol/L. Synonyms: 14-Hydroxysaframycin A; Propanamide, N-[[(5S,6R,7R,9R,14aS,15R)-7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-[(7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-oxo-, [5S-(5a,6a,7a,9b,14aa,15a)]-; (-)-Saframycin G; Propanamide, N-((7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-5-hydroxy-2,11-dimethoxy-3,12,16-trimethyl-1-4-10,13-tetraoxo-6,15-imino-4H-isoquino(3,2-b)(3)benzazocin-9-yl)methyl)-2-oxo-, (5S-(5alpha, 6alpha, 7alpha, 9beta, 14aalpha, 15alpha))-. CAS No. 92569-02-3. Molecular formula: C29H30N4O9. Mole weight: 578.57. | |
| Saframycin H | It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.033 μmol/L. Synonyms: 25-Dihydro-25-beta-ketopropylsaframycin A; Pentanamide, N-[(7-cyano-1,5,6,7,9,10,13,14,14a,15-decahydro-2,11-dimethoxy-3,12,16-trimethyl-1,4,10,13-tetraoxo-6,15-imino-4H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-hydroxy-2-methyl-4-oxo-, (1R,2S,10R,13S)-. CAS No. 92569-01-2. Molecular formula: C32H36N4O9. Mole weight: 620.65. | |
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