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| Product | Description | |
|---|---|---|
| S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine | S-(Acetamidomethyl)-N-(tert-butoxycarbonyl)-L-cysteine is a cysteine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19746-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g. Product ID: HY-W004153. |  |
| S-Acetyl-3-mercaptopropionic acid-N-hydroxysuccinimide ester ≥97% (NMR) | S-Acetyl-3-mercaptopropionic acid-N-hydroxysuccinimide ester ≥97% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. |  Worldwide |
| S-Acetyl-coenzyme A synthetase from baker's yeast (S. cerevisiae) | S-Acetyl-coenzyme A synthetase from baker's yeast (S. cerevisiae). Uses: For analytical and research use. CAS No. 9012-31-1. EC Number: 232-729-7. Catalog: AP9012311. |  |
| S-acetylglutathione | S-acetylglutathione is a glutathione derivative that has been shown to inhibit the replication of herpes simplex virus 1 (HSV-1) in human foreskin fibroblasts when used at concentrations of 5 and 10 mM. Alternative Names: S-acetyl-L-glutathione; Glutathione-S-acetate; 5-[[3-acetylsulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-2-amino-5-oxopentanoic acid. Grades: >98%. CAS No. 3054-47-5. Molecular formula: C12H19N3O7S. Mole weight: 349.36. |  |
| S-Acetyl-L-Glutathione(Italian & Chinese) | S-Acetyl-L-Glutathione(Italian & Chinese). |  CA, FL & NJ |
| S-Acetylmercaptosuccinic anhydride | S-Acetylmercaptosuccinic anhydride. Group: Biochemicals. Grades: Highly Purified. CAS No. 6953-60-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| S-Acetylmercaptosuccinic anhydride 99+% (NMR) | S-Acetylmercaptosuccinic anhydride 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| S-Acetyl-PEG3-azide | S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1310827-26-9. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-140859. | |
| S-acetyl-PEG4-propargyl | S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1422540-88-2. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-141350. | |
| S-acetyl-PEG6-alcohol | S-acetyl-PEG6-alcohol. CAS No. 1352221-63-6. Purity: 95%+. Product ID: ACM1352221636. Molecular formula: C14H28O7S. Mole weight: 340.43. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| S-Acetylthioacetic acid | S-Acetylthioacetic acid. Group: Biochemicals. Alternative Names: Acetylthioglycolic acid; Mercapto-acetic acid acetate; S-Acetylmercaptoacetic acid. Grades: Highly Purified. CAS No. 1190-93-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C4H6O3S. US Biological Life Sciences. | Worldwide |
| S-Acetylthiocholine iodide | S-Acetylthiocholine iodide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1866-15-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H16INOS. US Biological Life Sciences. | Worldwide |
| s-Acetylthioglycolic acid pentafluorophenyl ester | s-Acetylthioglycolic acid pentafluorophenyl ester. CAS No. 129815-48-1. Purity: 95%. Product ID: ACM129815481. Molecular formula: C10H5F5O3S. Mole weight: 300.2. Alfa Chemistry - ISO 9001:32057 Certified. | |
| S-Acetylthioglycolic acid pentafluorophenyl ester | Used for linking synthetic peptide antigens to MAP core peptides or carrier proteins for the purpose of raising antibodies. Alternative Names: SAMA-OPfp; Pentafluorophenyl-S-acetylthioglycolate. Grades: ≥ 98 % (HPLC). CAS No. 129815-48-1. Molecular formula: C10H5O3F5S. Mole weight: 300.10. | |
| S-Acetylthioglycolic acid pentafluorophenyl ester 98+% (HPLC) | S-Acetylthioglycolic acid pentafluorophenyl ester 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Sacituzumab | Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HRS7; hRS7. CAS No. 1796566-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99045. | |
| Sacituzumab | Sacituzumab is a humanized monoclonal antibody directed against Trop-2. Sacituzumab has been used in the research of metastatic triple-negative breast cancer. CAS No. 1796566-95-4. | |
| Sacituzumab (anti-Trop-2) | Sacituzumab (anti-Trop-2) is a fully humanized IgG1 kappa monoclonal antibody that binds Trop-2. Group: Antibodies. CAS No. 1796566-95-4. Pack Sizes: 1mg. Product ID: A2031. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles. |  United States; Europe |
| Sacituzumab govitecan | Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38, showing anticancer activity. Sacituzumab govitecan has a molecular weight of 160KDa. This product is supplied as 10mg/ml PBS solution. Alternative Names: IMMU-132. CAS No. 1491917-83-9 (Sacituzumab govitecan). Pack Sizes: 1mg. Product ID: D4002. Formula: 7.6. Storage Conditions: Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. | United States; Europe |
| Sacituzumab govitecan | Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU-132. CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132254. | |
| Sacituzumab govitecan | Sacituzumab govitecan is an antibody-drug conjugate with an SN-38 payload targeting trophoblast cell-surface antigen 2, an epithelial antigen expressed in breast cancer. Alternative Names: IMMU-132; IMMU 132; IMMU132. CAS No. 1491917-83-9. | |
| Sacituzumab govitecan (solution) | Sacituzumab govitecan (IMMU-132) is an antibody-drug conjugate (ADC) targeting Trop-2 for delivery of SN-38. The antibody portion is Sacituzumab (HY-P99045), and the drug-linker conjugate for ADC is CL2A-SN-38 (HY-128946). Sacituzumab govitecan shows anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU-132 (solution). CAS No. 1491917-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132254A. | |
| Sacituzumab tirumotecan | Sacituzumab tirumotecan is an antibody-drug conjugate and TROP2-directed, topoisomerase I inhibitor payload-delivering agent, with a TROP2 EC50 of 2.787 ng/ml, TROP2 Ka of 0.3083 nM, and topoisomerase I IC50 of 0.7 μmol/L. Sacituzumab tirumotecan can be used for the research of metastatic triple-negative breast cancer, and metastatic non-small cell lung cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKB264; MK-2870. CAS No. 2768350-77-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164789. | |
| SACLAC | SACLAC, a Ceramide analog, is a potent and covalent acid ceramidase (ASAH1; AC) inhibitor with a Ki of 97.1 nM. SACLAC effectively blocks AC activity and induces a decrease in sphingosine 1-phosphate (S1P) and total ceramide levels. SACLAC reduces the levels of splicing factor SF3B1 and alternative Mcl-1 mRNA splicing, increases pro-apoptotic Mcl-1S levels to induce apoptosis in acute myeloid leukemia (AML) cells. SACLAC reduces the leukemic burden in human AML xenograft mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2248703-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158783. | |
| Saclofen | Saclofen is an orally active and a competitive GABAB receptor antagonist with an IC50 of 7.8 μM. Saclofen has weak antagonistic effects on GABAB1b and GABAB2 heterodimeric recombinant receptors. Saclofen inhibits the binding of Baclofen (HY-B0007) to rat cerebellar membranes and blocks Baclofen-induced circadian phase shifts, and exhibits anti-inflammatory and analgesic effects in rats[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 125464-42-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100813. | |
| Saclofen | Saclofen. Group: Biochemicals. Grades: Purified. CAS No. 125464-42-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sacubitril | Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AHU-377. CAS No. 149709-62-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-15407. | |
| Sacubitril | Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Alternative Names: Sacubitril; AHU 377; AHU377. Grades: >98%. CAS No. 149709-62-6. Molecular formula: C24H29NO5. Mole weight: 411.49. | |
| Sacubitril-(2S, 4S)-Isomer | Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Alternative Names: (2S,4S)-Sacubitril; 149709-63-7; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; 4-[[(2S,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; [1,1'-Biphenyl]-4-pentanoic acid, gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl-, alpha-ethyl ester, (alphaS,gammaS)-; LCZ 696 Impurity C; SCHEMBL18059568; DTXSID901127620; AKOS030528363; AS-80403; HY-78841; CS-0009335; 3-{[(2S,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2S,4S)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoicacid; alpha-Ethyl (alphaS,gammaS)-gamma-[(3-carboxy-1-oxopropyl)amino]-alpha-methyl[1,1'-biphenyl]-4-pentanoate. Grades: > 95%. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5. | |
| Sacubitrilat | Sacubitrilat. CAS No. 149709-44-4. | |
| Sacubitrilat | Sacubitrilat (Desethyl Sacubitril) is an active neprilysin (NEP) inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Desethyl Sacubitril; LBQ-657. CAS No. 149709-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17620. | |
| Sacubitril-[d4] | An isotope labelled AHU377, a methyl ester prodrug form of the neprilysin inhibitor LBQ657. Alternative Names: AHU377-d4; (alphaR,gammaS)-gamma-[(3-carboxy-1-oxopropyl-2,2,3,3-d4)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoicacid,alpha-ethylester. Grades: ≥99% atom D. CAS No. 1884269-07-1. Molecular formula: C24H25D4NO5. Mole weight: 415.5. | |
| Sacubitril Enantiomer | Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Alternative Names: 2R,4S-Sacubitril; (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester; 4-[[(2R,4S)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid; (2S,4R)-Sacubitril; SCHEMBL22420467; CS-M3545; AKOS030528367; HY-78847; MS-27102; PD100765; L10003; EN300-6474615; A854860; [1,1'-Biphenyl]-4-pentanoic acid, |A-[(3-carboxy-1-oxopropyl)amino]-|A-methyl-, 4-ethyl ester, (|AS,|AR)-; 3-{[(2R,4S)-1-{[1,1'-biphenyl]-4-yl}-5-ethoxy-4-methyl-5-oxopentan-2-yl]carbamoyl}propanoic acid; 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid; (alphaS,gammaR)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester. Grades: > 95%. CAS No. 761373-05-1. Molecular formula: C24H29NO5. Mole weight: 411.5. | |
| Sacubitril impurity 10 | Sacubitril impurity 10. Uses: For analytical and research use. CAS No. 2259708-00-2. Molecular formula: C24H29NO5. Mole weight: 411.5. Catalog: APB2259708002. | |
| Sacubitril impurity 11 | Sacubitril impurity 11. Uses: For analytical and research use. CAS No. 1038924-70-7. Molecular formula: C18H19NO. Mole weight: 265.36. Catalog: APB1038924707. | |
| Sacubitril impurity 12 | Sacubitril impurity 12. Uses: For analytical and research use. CAS No. 1038924-71-8. Molecular formula: C18H22ClNO2. Mole weight: 319.83. Catalog: APB1038924718. | |
| Sacubitril impurity 13 | Sacubitril impurity 13. Uses: For analytical and research use. Molecular formula: C18H21NO2. Mole weight: 283.37. Catalog: APB11708. | |
| Sacubitril impurity 14 | Sacubitril impurity 14. Uses: For analytical and research use. CAS No. 2751722-77-5. Molecular formula: C24H27NO5. Mole weight: 409.48. Catalog: APB2751722775. | |
| Sacubitril impurity 15 | Sacubitril impurity 15. Uses: For analytical and research use. Molecular formula: C24H28N5O4. Mole weight: 450.52. Catalog: APB09694. | |
| Sacubitril impurity 16 | Sacubitril impurity 16. Uses: For analytical and research use. Molecular formula: C50H60CaN2O10. Mole weight: 889.11. Catalog: APB09696. | |
| Sacubitril impurity 17 | Sacubitril impurity 17. Uses: For analytical and research use. CAS No. 1884269-07-1. Molecular formula: C24H25D4NO5. Mole weight: 415.52. Catalog: APB1884269071. | |
| Sacubitril impurity 18 | Sacubitril impurity 18. Uses: For analytical and research use. CAS No. 149818-98-4. Molecular formula: C21H25NO4. Mole weight: 355.43. Catalog: APB149818984. | |
| Sacubitril impurity 20 | Sacubitril impurity 20. Uses: For analytical and research use. CAS No. 149709-60-4. Molecular formula: C25H33NO4. Mole weight: 411.54. Catalog: APB149709604. | |
| Sacubitril impurity 21 | Sacubitril impurity 21. Uses: For analytical and research use. CAS No. 2459446-54-7. Molecular formula: C22H23NO4. Mole weight: 365.43. Catalog: APB2459446547. | |
| Sacubitril impurity 22 | Sacubitril impurity 22. Uses: For analytical and research use. CAS No. 2216755-67-6. Molecular formula: C28H37NO5. Mole weight: 467.61. Catalog: APB2216755676. | |
| Sacubitril impurity 23 | Sacubitril impurity 23. Uses: For analytical and research use. CAS No. 2459446-53-6. Molecular formula: C27H35NO5. Mole weight: 453.58. Catalog: APB2459446536. | |
| Sacubitril impurity 24 | Sacubitril impurity 24. Uses: For analytical and research use. CAS No. 2514965-95-6. Molecular formula: C25H31NO5. Mole weight: 425.53. Catalog: APB2514965956. | |
| Sacubitril impurity 25 | Sacubitril impurity 25. Uses: For analytical and research use. CAS No. 2459446-51-4. Molecular formula: C25H31NO5. Mole weight: 425.53. Catalog: APB2459446514. | |
| Sacubitril impurity 26 | Sacubitril impurity 26. Uses: For analytical and research use. CAS No. 2408053-56-3. Molecular formula: C23H27NO5. Mole weight: 397.47. Catalog: APB2408053563. | |
| Sacubitril impurity 27 | Sacubitril impurity 27. Uses: For analytical and research use. Molecular formula: C48H58CaN2O102+. Mole weight: 863.07. Catalog: APB11724. | |
| Sacubitril impurity 28 | Sacubitril impurity 28. Uses: For analytical and research use. Molecular formula: C48H58CaN2O102+. Mole weight: 863.07. Catalog: APB11726. | |
| Sacubitril impurity 29 | Sacubitril impurity 29. Uses: For analytical and research use. Molecular formula: C48H58CaN2O102+. Mole weight: 863.07. Catalog: APB11725. | |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Alternative Names: (3S,5S)-5-biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one; (3S,5S)-5-[(Biphenyl-4-yl)methyl]-3-methylpyrrolidin-2-one. Grades: > 95%. CAS No. 1038925-00-6. Molecular formula: C18H19NO. Mole weight: 265.36. | |
| Sacubitril impurity 30 | Sacubitril impurity 30. Uses: For analytical and research use. CAS No. 149709-49-9. Molecular formula: C24H29NO5. Mole weight: 411.5. Catalog: APB149709499. | |
| Sacubitril impurity 31 | Sacubitril impurity 31. Uses: For analytical and research use. CAS No. 153037-40-2. Molecular formula: C20H25NO3. Mole weight: 327.42. Catalog: APB153037402. | |
| Sacubitril impurity 32 | Sacubitril impurity 32. Uses: For analytical and research use. Molecular formula: C20H25NO3. Mole weight: 327.42. Catalog: APB11727. | |
| Sacubitril impurity 33 | Sacubitril impurity 33. Uses: For analytical and research use. Molecular formula: C28H40N2O6. Mole weight: 500.64. Catalog: APB11728. | |
| Sacubitril Impurity 4 | Sacubitrilat is one of the impurities of Sacubitril which has been found to be an endopeptidase inhibitor and be effective in the treatment of hypertension and heart failure. Alternative Names: LBQ-657; LBQ 657; LBQ657; Sacubitrilat; UNII-SPI5PBF81S; LBQ657; CHEMBL417007; (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid. Grades: 98%. CAS No. 149709-44-4. Molecular formula: C22H25NO5. Mole weight: 383.44. | |
| Sacubitril Impurity 4 | Sacubitril Impurity 4. Uses: For analytical and research use. CAS No. 149709-44-4. Molecular formula: C22H25NO5. Mole weight: 383.44. Catalog: APB149709444. | |
| Sacubitril Impurity 5 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Alternative Names: (αR,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril impurity 6 | Sacubitril impurity 6. Uses: For analytical and research use. Molecular formula: C24H27NO5. Mole weight: 409.48. Catalog: APB11700. | |
| Sacubitril Impurity 6 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Alternative Names: (αS,γR)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril impurity 7 | Sacubitril impurity 7. Uses: For analytical and research use. CAS No. 2751722-75-3. Molecular formula: C24H27NO5. Mole weight: 409.48. Catalog: APB2751722753. | |
| Sacubitril Impurity 7 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Alternative Names: (αS,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic Acid. Grades: > 95%. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.49. | |
| Sacubitril impurity 8 | Sacubitril impurity 8. Uses: For analytical and research use. CAS No. 766480-48-2. Molecular formula: C24H29NO5. Mole weight: 411.5. Catalog: APB766480482. | |
| Sacubitril impurity 9 | Sacubitril impurity 9. Uses: For analytical and research use. CAS No. 149709-63-7. Molecular formula: C24H29NO5. Mole weight: 411.5. Catalog: APB149709637. | |
| Sacubitril sodium | Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19. Category: Active pharmaceutical ingredients. CAS No. 149690-05-1. Product ID: API149690051. Molecular formula: C24H28NNaO5. Mole weight: 433.473. |  |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Alternative Names: sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696. CAS No. 149690-05-1. Molecular formula: C24H28NO5.Na. Mole weight: 433.47. | |
| Sacubitril sodium | Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AHU-377 sodium. CAS No. 149690-05-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15407B. | |
| Sacubitril/Valsartan | Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis[4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LCZ696. CAS No. 936623-90-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18204A. | |
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