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| Product | Description | |
|---|---|---|
| TA DNA Polymerase | TA DNA Polymerase. Ta dna polymerase is a mixture of taq dna polymerase with a proofreading 3-5 exonuclease. the fidelity is equal to hifi pfu dna polymerase. the yield is equal to that from taq dna polymerase. it is more suitable for high fidelity ta cloning. ta dna polymerase offers 18-fold fidelity as compared to taq dna polymerase. extension rate is about 1-2 kb/min. template-independentacan be generated at the 3end of the pcr product. amplification of genomic dna fragment up to 8 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3024. |  |
| Tadnersen | Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIIB078; IONIS-C9Rx. CAS No. 2170507-65-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132581. |  |
| Tadocizumab | Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C4G1; YM-337. CAS No. 339086-80-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99560. | |
| TAE648 | TAE648 is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). TAE648 can be used for synthesis PROTAC SK-3-91 (HY-137341)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769753-10-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169396. | |
| TAE 684 | TAE 684. Group: Biochemicals. Alternative Names: NVP-TAE 684; NVT TAE-684; 5-Chloro-N2-[2-methoxy-4-[4- (4-methyl-1-piperazinyl) -1-piperidinyl]phenyl]-N4-[2-[ (1-methylethyl) sulfonyl]phenyl]-2, 4-pyrimidinediamine. Grades: Highly Purified. CAS No. 761439-42-3. Pack Sizes: 10mg. Molecular Formula: C30H40ClN7O3S, Molecular Weight: 614.2. US Biological Life Sciences. |  Worldwide |
| TAE buffer (50X) | 1lt Pack Size. Group: Biochemicals, Buffers. Formula: N/A. Prepack ID 12439469-1lt. See USA prepack pricing. |  |
| Tafamidis | Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis. It has a role as a central nervous system drug. Category: Other apis. Synonyms: Vyndamax. FX-1006. 2-(3,5-Dichlorophenyl)-1,3-Benzoxazole-6-Carboxylic Acid. CAS No. 594839-88-0. Product ID: API594839880. Molecular formula: C14H7Cl2NO3. Mole weight: 308.1. SMILES: C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl. |  |
| Tafamidis | Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 594839-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852. | |
| Tafamidis-[d3] | Tafamidis-[d3] is deuterium labelled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, showing comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis. Synonyms: Tafamidis-d3; d3-Tafamidis. Molecular formula: C14H4D3Cl2NO3. Mole weight: 311.13. |  |
| Tafamidis meglumine | Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Fx-1006A. CAS No. 951395-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852A. | |
| Tafamidis (Standard) | Tafamidis (Standard) is the analytical standard of Tafamidis. This product is intended for research and analytical applications. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 594839-88-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852R. | |
| Tafasitamab | Tafasitamab (XmAb5574) is an Fc-modified, humanized monoclonal antibody that binds to the human B-cell surface antigenCD19[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XmAb5574; MOR00208; Tafasitamab-cxix; MOR-208. CAS No. 1422527-84-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9981. | |
| Tafenoquine | Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WR 238605. CAS No. 106635-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529. | |
| Tafenoquine | Tafenoquine is an 8-aminoquinoline,and is an agent of anti-malarial prophylactic. Category: Active pharmaceutical ingredients. Synonyms: WR 238605. CAS No. 106635-80-7. Product ID: API106635807. Molecular formula: C24H28F3N3O3. Mole weight: 463.49. | |
| Tafenoquine Succinate | Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: WR 238605 Succinate. CAS No. 106635-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111529A. | |
| Tafenoquine Succinate | Tafenoquine Succinate (WR 238605 (Succinate)) is an 8-aminoquinoline. and is an agent of anti-malarial prophylactic. Category: Active pharmaceutical ingredients. CAS No. 106635-81-8. Product ID: API106635818. Molecular formula: C28H34F3N3O7. Mole weight: 581.58. | |
| Tafluprost | Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α. Category: Active pharmaceutical ingredients. CAS No. 209860-87-7. Product ID: API209860877. Molecular formula: C25H34F2O5. Mole weight: 452.53. | |
| Tafluprost | Tafluprost (AFP-168) is an anti-glaucoma prostaglandin (PG) analog. Tafluprost can inhibit the apoptosis of retinal ganglion cells (RGCs) and rat RGCs cells. Tafluprost promotes axon regeneration by regulating Zn2+-mTORpathway, inhibits intracellular lipid accumulation in human preorbital adipocytes. Tafluprost can be used in the study of optic nerve injury in glaucoma[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AFP-168; MK2452. CAS No. 209860-87-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0600. | |
| Tafluprost | Tafluprost. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylmethyl Ester; AFP 168; MK 2452; Taflotan; Tapros. Grades: Highly Purified. CAS No. 209860-87-7. Pack Sizes: 2.5mg. Molecular Formula: C25H34F2O5, Molecular Weight: 452.53. US Biological Life Sciences. | Worldwide |
| Tafluprost acid | Tafluprost acid (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist. Tafluprost acid shows a high affinity for human prostanoid FP receptor with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Tafluprost acid has 126 times weaker binding affinity for prostanoid EP3 receptor (IC50=67 nM) than for the prostanoid FP receptor. Tafluprost acid can be used in the research of glaucoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AFP-172. CAS No. 209860-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0601. | |
| Tafluprost-d7 | Tafluprost-d7. Group: Biochemicals. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid 1-Methylmethyl Ester-d7; AFP 168-d7; MK 2452-d7; Taflotan-d7; Tapros-d7. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H27D7F2O5, Molecular Weight: 459.57. US Biological Life Sciences. | Worldwide |
| Tafluprost Impurity 10 | Tafluprost Impurity 10. Uses: For analytical and research use. CAS No. 40665-68-7. Molecular formula: C11H15O5P. Mole weight: 258.21. Catalog: APB40665687. |  |
| Tafluprost Impurity 11 | Tafluprost Impurity 11. Uses: For analytical and research use. CAS No. 39746-00-4. Molecular formula: C15H16O5. Mole weight: 276.29. Catalog: APB39746004. | |
| Tafluprost Impurity 12 | Tafluprost Impurity 12. Uses: For analytical and research use. Molecular formula: C25H33F3O5. Mole weight: 470.53. Catalog: APB09865. | |
| Tafluprost Impurity 13 | Tafluprost Impurity 13. Uses: For analytical and research use. Molecular formula: C25H33FO5. Mole weight: 432.53. Catalog: APB09866. | |
| Tafluprost Impurity 15 | Tafluprost Impurity 15. Uses: For analytical and research use. Molecular formula: C25H33FO5. Mole weight: 432.53. Catalog: APB09868. | |
| Tafluprost Impurity 19 | Tafluprost Impurity 19. Uses: For analytical and research use. CAS No. 2587078-46-2. Molecular formula: C25H35FO5. Mole weight: 434.55. Catalog: APB2587078462. | |
| Tafluprost Impurity 20 | Tafluprost Impurity 20. Uses: For analytical and research use. Molecular formula: C25H34F2O6. Mole weight: 468.54. Catalog: APB09867. | |
| Tafluprost Impurity 21 | Tafluprost Impurity 21. Uses: For analytical and research use. Molecular formula: C24H32F2O5. Mole weight: 438.51. Catalog: APB09869. | |
| Tafluprost Impurity 22 | Tafluprost Impurity 22. Uses: For analytical and research use. CAS No. 2587078-47-3. Molecular formula: C25H34F2O5. Mole weight: 452.54. Catalog: APB2587078473. | |
| Tafluprost Impurity 7 | Tafluprost Impurity 7. Uses: For analytical and research use. CAS No. 733036-94-7. Molecular formula: C25H35FO5. Mole weight: 434.55. Catalog: APB733036947. | |
| Tafluprost Impurity 8 | Tafluprost Impurity 8. Uses: For analytical and research use. CAS No. 2278245-92-2. Molecular formula: C27H41BrO5. Mole weight: 525.52. Catalog: APB2278245922. | |
| Tafluprost Impurity 8 | Tafluprost Impurity 8. Uses: For analytical and research use. Alternative Names: (3aR,4S,5S,6aS)-4-(hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate. Molecular formula: C15H16O5. Mole weight: 276.28. Catalog: APB01978. | |
| Tafluprost Impurity 9 | Tafluprost Impurity 9. Uses: For analytical and research use. Alternative Names: (3aR,4R,5R,6aS)-4-(hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate. Molecular formula: C15H16O5. Mole weight: 276.28. Catalog: APB01975. | |
| Tafluprost Impurity 9 | Tafluprost Impurity 9. Uses: For analytical and research use. CAS No. 2099033-66-4. Molecular formula: C27H41NO8. Mole weight: 507.62. Catalog: APB2099033664. | |
| Tafluprost Impurity DCP-1 | Tafluprost Impurity DCP-1. Uses: For analytical and research use. CAS No. 209860-88-8. Molecular formula: C22H28F2O5. Mole weight: 410.46. Catalog: APB209860888. | |
| Tafluprost Impurity DCP-2 | Tafluprost Impurity DCP-2. Uses: For analytical and research use. CAS No. 1563176-58-8. Molecular formula: C25H34F2O5. Mole weight: 452.54. Catalog: APB1563176588. | |
| TAG-1 A2 (78-86) | TAG-1 A2 (78-86). | |
| TAG-2 (42-50) | TAG-2 (42-50). | |
| Tagarafdeg | Tagarafdeg (CFT1946) is an orally active, CRBN-based and mutant-selective bifunctional degradation activating compound (BiDAC) degrader of BRAFV600E with a DC50 of 14 nM in A375 cells. Tagarafdeg is capable of degrading BRAF V600E (Class I), G469A (Class II), G466V (Class III) mutations, and the p61-BRAFV600E splice variant. Tagarafdeg can be used in tumor research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CFT1946. CAS No. 2882165-79-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-153341. | |
| Tagatose | Tagatose is a white, anhydrous crystalline solid. It is a carbohydrate, a ketohexose, an epimer of D-fructose inverted at C-4. It can exist in several tautomeric forms. Synonyms: D-lyxo-Hexulose; (3S, 4S, 5R)-2-(hydroxymethyl)oxane-2, 3, 4, 5- tetrol; Naturlose; D-tagatose; tagatosum; tagatoza. CAS No. 87-81-0. Product ID: PE-0495. Molecular formula: C6H12O6. Mole weight: 180.16. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Tagatose; Sweeteners Excipients; Sweetening agent; C6H12O6; 87-81-0; 87-81-0. UNII: T7A20Y888Y. Chemical Name: (3S, 4S, 5R)-1, 3, 4, 5, 6-pentahydroxyhexan-2-one. Administration route: oral and rectal. Dosage Form: oral and rectal solutions. Stability and Storage Conditions: Tagatose is stable under pH conditions typically encountered in foods (pH > 3). It is a reducing sugar and undergoes the Maillard reaction. Tagatose is stable under typical storage conditions. It caramelizes at elevated temperature. Source and Preparation: Tagatose is obtained from D-galactose by isomerization under alkaline conditions in the presence of calcium. Applications: Tagatose is used as a sweetening agent in beverages, foods, and pharmaceutical applications. A 10% solution of tagatose is about 92% as sweet as a 10% sucrose solution.It is a low-calorie sugar with approximately 38% of the calories of sucrose per gram. It occurs naturally in low levels in milk pro |  |
| Tagatose-6-phosphate | Tagatose-6-phosphate. Alternative Names: TAGATOSE-6-PHOSPHATE. CAS No. 136377-13-4. Product ID: ACM136377134. Molecular formula: C6H13O9P. Mole weight: 260.135781. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| tagatose-6-phosphate kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.144. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2974; tagatose-6-phosphate kinase; EC 2.7.1.144; 39434-00-9. Cat No: EXWM-2974. | |
| tagatose-bisphosphate aldolase | Enzyme activity is stimulated by certain divalent cations. It is involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria. Group: Enzymes. Synonyms: D-tagatose-1,6-bisphosphate triosephosphate lyase. Enzyme Commission Number: EC 4.1.2.40. CAS No. 39433-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4876; tagatose-bisphosphate aldolase; EC 4.1.2.40; 39433-95-9; D-tagatose-1,6-bisphosphate triosephosphate lyase. Cat No: EXWM-4876. | |
| tagatose kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.101. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2948; tagatose kinase; EC 2.7.1.101; 39434-00-9. Cat No: EXWM-2948. | |
| tagaturonate reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-altronate:NAD+ 3-oxidoreductase. Other names in common use include altronic oxidoreductase, altronate oxidoreductase, TagUAR, altronate dehydrogenase, and D-tagaturonate reductase. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Enzyme Commission Number: EC 1.1.1.58. CAS No. 9028-45-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0343; tagaturonate reductase; EC 1.1.1.58; 9028-45-9; altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Cat No: EXWM-0343. | |
| Tagette Oil | Tagette Oil. CAS No. 8016-84-0. FEMA No. 3040. Kosher: Y. VIGON Item # 504279. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. |  America & Internationally |
| Tagitanlimab | Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HBM-9167; KL-A167. CAS No. 2417649-97-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99544. | |
| Tagmokitug | Tagmokitug (CHS-114; SRF-114) is a fully human IgG1 antibody targeting CCR8. Tagmokitug selectively binds to human CCR8 (Kd = 502 pM) and mediates the death of CCR8-expressing cells via antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. Tagmokitug selectively eliminates intratumoral regulatory T cells, induces tumor growth inhibition, remodels the tumor immune microenvironment, and promotes the differentiation of cytotoxic CD8+ T cell subsets. Tagmokitug can be used for the research of solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHS-114; SRF-114. CAS No. 3024486-14-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991061. | |
| Tagtociclib hydrate | PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-07104091 hydrate. CAS No. 2733575-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137894A. | |
| Tagtociclib (PF-07104091) | Tagtociclib (PF-07104091) inhibits CDK2, which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. Group: Inhibitors. CAS No. 2460249-19-6. Pack Sizes: 5mg. Product ID: S9878. Formula: C19H28N6O4. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| Taipehensin-B1 antimicrobial peptide precursor | Taipehensin-B1 antimicrobial peptide precursor is an antibacterial peptide isolated from Hylarana taipehensis. Synonyms: Thr-Met-Lys-Lys-Leu-Leu-Leu-Leu-Phe-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Ser-Ser-Leu-Cys-Glu-Lys-Glu-Arg-Asp-Ala-Asp-Glu-Asp-Glu-Val-Asn-Arg-Gly-Glu-Ala. Grade: >98%. | |
| TAK-020 | TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627603-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132879. | |
| TAK-071 | TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1820812-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122190. | |
| TAK 165 | TAK 165. Group: Biochemicals. Grades: Purified. CAS No. 366017-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK1/MAP4K2 inhibitor 1 | TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41.1 nM and 18.2 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1315330-11-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-77251. | |
| TAK 21d | TAK 21d. Group: Biochemicals. Grades: Purified. CAS No. 1143578-94-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK-243 | TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MLN7243. CAS No. 1450833-55-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100487. | |
| TAK-243 | TAK-243 Inhibitor. Uses: Scientific use. Product Category: T16974. CAS No. 1450833-55-2. |  |
| TAK-243 (MLN7243) | TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. TAK-243 (MLN7243) induces ER stress, abrogates NFκB pathway activation and promotes apoptosis. Group: Inhibitors. CAS No. 1450833-55-2. Pack Sizes: 2mg. Product ID: S8341. Formula: C19H20F3N5O5S2. Smiles: N[S;v6](=O)(=O)OCC1CC(NC2=CC=NC3=CC(=N[N]23)C4=CC(=CC=C4)SC(F)(F)F)C(O)C1O. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| TAK-285 | TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier (BBB)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 871026-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15196. | |
| TAK-418 | TAK-418 is a selective, orally active LSD1 (KDM1A) enzyme inhibitor with an IC50 of 2.9 nM. TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1818252-53-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138830. | |
| TAK-438 | TAK-438 Inhibitor. Uses: Scientific use. Product Category: T2404. CAS No. 1260141-27-2. | |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grade: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. | |
| TAK-448 | TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MVT-602. CAS No. 1234319-68-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0076. | |
| TAK-448 acetate | It is an agonist of KISS1R protein, and is an oligopeptide analogue of kisspeptin. Synonyms: MVT-602 (acetate); Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg (Me)-Trp-NH2 acetate; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide acetate (1:1). Grade: ≥98%. CAS No. 1470374-22-1. Molecular formula: C58H80N16O14.C2H4O2. Mole weight: 1285.41. | |
| TAK-448 acetate | TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MVT-602 acetate. CAS No. 1470374-22-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0076A. | |
| TAK-593 | TAK-593 is a potent VEGFR and PDGFR family inhibitor with IC50s of 3.2, 0.95, 1.1, 4.3 and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα and PDFGRβ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1005780-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15506. | |
| TAK-615 | TAK-615 is a negative allosteric modulator (NAM) of the LPA1 receptor for the research of pulmonary fibrosis. TAK-615 binds the LPA1 receptor with high affinity (Kd high affinity of 1.7 nM and Kd low affinity of 14.5 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1664335-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117959. | |
| TAK-632 | TAK-632 is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAFV600E, BRAFWT, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228591-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15767. | |
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