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| Product | Description | |
|---|---|---|
| Tagatose-6-phosphate | Tagatose-6-phosphate. Alternative Names: TAGATOSE-6-PHOSPHATE. CAS No. 136377-13-4. Product ID: ACM136377134. Molecular formula: C6H13O9P. Mole weight: 260.135781. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| tagatose-6-phosphate kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.144. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2974; tagatose-6-phosphate kinase; EC 2.7.1.144; 39434-00-9. Cat No: EXWM-2974. |  |
| tagatose-bisphosphate aldolase | Enzyme activity is stimulated by certain divalent cations. It is involved in the tagatose 6-phosphate pathway of lactose catabolism in bacteria. Group: Enzymes. Synonyms: D-tagatose-1,6-bisphosphate triosephosphate lyase. Enzyme Commission Number: EC 4.1.2.40. CAS No. 39433-95-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4876; tagatose-bisphosphate aldolase; EC 4.1.2.40; 39433-95-9; D-tagatose-1,6-bisphosphate triosephosphate lyase. Cat No: EXWM-4876. | |
| tagatose kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. This enzyme participates in galactose metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.7.1.101. CAS No. 39434-00-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2948; tagatose kinase; EC 2.7.1.101; 39434-00-9. Cat No: EXWM-2948. | |
| tagaturonate reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-altronate:NAD+ 3-oxidoreductase. Other names in common use include altronic oxidoreductase, altronate oxidoreductase, TagUAR, altronate dehydrogenase, and D-tagaturonate reductase. This enzyme participates in pentose and glucuronate interconversions. Group: Enzymes. Synonyms: altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Enzyme Commission Number: EC 1.1.1.58. CAS No. 9028-45-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0343; tagaturonate reductase; EC 1.1.1.58; 9028-45-9; altronic oxidoreductase; altronate oxidoreductase; TagUAR; altronate dehydrogenase; D-tagaturonate reductase. Cat No: EXWM-0343. | |
| Tagetes oil | Tagetes oil is an organic essential oil extracted from the Tagetes plant exhibiting inherent anti-inflammatory and antimicrobial attributes. Its employment in the research of diverse skin infections, wounds and dermatological conditions has been extensively recognized. Alternative Names: Cydonia oil; Oil of Tagetes glandulifera; oils, beta agetes; Oils, Tagetes; Tagette oil. CAS No. 8016-84-0. Molecular formula: Tb84. Mole weight: 13349.73. |  |
| Tagette Oil | Tagette Oil. CAS No. 8016-84-0. FEMA No. 3040. Kosher: Y. VIGON Item # 504279. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. |  America & Internationally |
| Tagitanlimab | Tagitanlimab (HBM-9167) is a humanized anti-PD-L1 antibody (IgG1κ type). Tagitanlimab selectively blocks the interaction of PD-L1 and PD-1. Tagitanlimab has the potential to be studied in recurrent or metastatic nasopharyngeal carcinoma (NPC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HBM-9167; KL-A167. CAS No. 2417649-97-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99544. |  |
| Tagitinim C | Tagitinim C is an antitrypanosomal compound from the moon flower, Tithonia diversifolia. Alternative Names: tagitinin C; (3aR,4R,6R,7E,10Z,11aR)-6-Hydroxy-6,10-dimethyl-3-methylene-2,9-dioxo-2,3,3a,4,5,6,9,11a-octahydrocyclodeca[b]furan-4-yl Isobutyrate. Grades: 95%. CAS No. 59979-56-5. Molecular formula: C19H24O6. Mole weight: 348.40. | |
| Tagmokitug | Tagmokitug (CHS-114; SRF-114) is a fully human IgG1 antibody targeting CCR8. Tagmokitug selectively binds to human CCR8 (Kd = 502 pM) and mediates the death of CCR8-expressing cells via antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. Tagmokitug selectively eliminates intratumoral regulatory T cells, induces tumor growth inhibition, remodels the tumor immune microenvironment, and promotes the differentiation of cytotoxic CD8+ T cell subsets. Tagmokitug can be used for the research of solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CHS-114; SRF-114. CAS No. 3024486-14-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P991061. | |
| Tagtociclib hydrate | PF-07104091 hydrate is a potent and selective CDK2/cyclin E1 and GSK3β inhibitor, with Kis of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E1-amplified cancers. (patent WO2020157652A2). Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-07104091 hydrate. CAS No. 2733575-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137894A. | |
| Tagtociclib (PF-07104091) | Tagtociclib (PF-07104091) inhibits CDK2, which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. Group: Inhibitors. CAS No. 2460249-19-6. Pack Sizes: 5mg. Product ID: S9878. Formula: C19H28N6O4. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| Taipehensin-B1 antimicrobial peptide precursor | Taipehensin-B1 antimicrobial peptide precursor is an antibacterial peptide isolated from Hylarana taipehensis. Alternative Names: Thr-Met-Lys-Lys-Leu-Leu-Leu-Leu-Phe-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Ser-Ser-Leu-Cys-Glu-Lys-Glu-Arg-Asp-Ala-Asp-Glu-Asp-Glu-Val-Asn-Arg-Gly-Glu-Ala. Grades: >98%. | |
| Taiwanin C | Taiwanin C. Grades: 97.5%. CAS No. 14944-34-4. Molecular formula: C20H12O6. | |
| Taiwanin E | Taiwanin E. Grades: 97.0%. CAS No. 22743-05-1. Molecular formula: C20H12O7. | |
| TAK-020 | TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627603-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132879. | |
| TAK-063 | TAK-063 is a highly potent, selective, and orally active phosphodiesterase 10A (PDE10A) inhibitor. TAK-063 is currently being evaluated in clinical trials for the treatment of schizophrenia. Phosphodiesterase 10A (PDE10A) is a cAMP / cGMP phosphodiesterase highly expressed in medium spiny neurons (MSNs) in the striatum. TAK-063 represents a promising drug for the treatment of schizophrenia with potential for superior safety and tolerability profiles. Alternative Names: TAK063, TAK 063, TAK-063, Balipodect. Grades: >98%. CAS No. 1238697-26-1. Molecular formula: C23H17FN6O2. Mole weight: 428.42. | |
| TAK-071 | TAK-071 is a positive allosteric modulator of muscarinic acetylcholine receptor 1 (M1R). Uses: Muscarinic agonists. Alternative Names: TAK-071; 1820812-16-5; UNII-59XC9G796Y; 59XC9G796Y; 4-Fluoro-2-((3S, 4S)-4-hydroxytetrahydro-2H-pyran-3-yl)-5-methyl-6-(4(1H-pyrazol-1-yl)benzyl)-2, 3-dihydro-1H-isoindol-1-one; L-Threo-pentitol, 1,5-anhydro-2,4-dideoxy-2-(4-fluoro-1,3-dihydro-5-methyl-1-oxo-6-((4-(1H-pyrazol-1-yl)phenyl)methyl)-2H-isoindol-2-yl)-; 4-fluoro-2-[(3S,4S)-4-hydroxyoxan-3-yl]-5-methyl-6-[(4-pyrazol-1-ylphenyl)methyl]-3H-isoindol-1-one; 6-(4-(1H-PYRAZOL-1-YL)BENZYL)-4-FLUORO-2-((3S,4S)-4-HYDROXYTETRAHYDRO-2H-PYRAN-3-YL)-5-METHYLISOINDOLIN-1-ONE; CHEMBL4594351; SCHEMBL17201222; GTPL12302; WFSARWQASFQZMG-VXKWHMMOSA-N; AKOS040739717; AC-31580; MS-27399; HY-122190; CS-0082523; D77973; 1,5-anhydro-2,4-dideoxy-2-(4-fluoro-5-methyl-1-oxo-6-(4-(1H-pyrazol-1-yl)benzyl)-1,3-dihydro-2H-isoindol-2-yl)-L-threo-pentitol; 4-fluoro-2-[(3s,4s)-4-hydroxytetrahydro-2h-pyran-3-yl]-5-methyl-6-[4-(1h-pyrazol-1-yl)benzyl]-2,3-dihydro-1h-isoindol-1-one. Grades: 98%. CAS No. 1820812-16-5. Molecular formula: C24H24FN3O3. Mole weight: 421.5. | |
| TAK-071 | TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1820812-16-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122190. | |
| TAK 165 | TAK 165. Group: Biochemicals. Grades: Purified. CAS No. 366017-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TAK1/MAP4K2 inhibitor 1 | TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41.1 nM and 18.2 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1315330-11-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-77251. | |
| TAK 21d | TAK 21d. Group: Biochemicals. Grades: Purified. CAS No. 1143578-94-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK-220 | TAK-220 is an orally bioavailable small-molecule CCR5 antagonist. Alternative Names: TAK-220, TAK 220, TAK220; 1-acetyl-N-[3-[4-[(4-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide. Grades: 99.95%. CAS No. 333994-00-6. Molecular formula: C31H41ClN4O3. Mole weight: 553.14. | |
| TAK-243 | TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MLN7243. CAS No. 1450833-55-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100487. | |
| TAK-243 | TAK-243, a pyrazolopyrimidine derivative, has been found to be an Ubiquitin-protein ligase inhibitor and was just finished the Phase-I trial against solid tumors. Alternative Names: TAK-243; TAK 243; TAK243; MLN7243; MLN-7243; MLN 7243; AOB87172; AOB-87172; AOB 87172. Grades: 98%. CAS No. 1450833-55-2. Molecular formula: C19H20F3N5O5S2. Mole weight: 519.51. | |
| TAK-243 | TAK-243 Inhibitor. Uses: Scientific use. Product Category: T16974. CAS No. 1450833-55-2. |  |
| TAK-243 (MLN7243) | TAK-243 (MLN7243) is a potent, mechanism-based small-molecule inhibitor of the ubiquitin activating enzyme (UAE) with an IC50 of 1 ± 0.2 nM in the UBCH10 E2 thioester assay. It has minimal inhibitory activity in a panel of kinase and receptor assays, as well as on human carbonic anhydrase type I and type II. TAK-243 (MLN7243) induces ER stress, abrogates NFκB pathway activation and promotes apoptosis. Group: Inhibitors. CAS No. 1450833-55-2. Pack Sizes: 2mg. Product ID: S8341. Formula: C19H20F3N5O5S2. Smiles: N[S;v6](=O)(=O)OCC1CC(NC2=CC=NC3=CC(=N[N]23)C4=CC(=CC=C4)SC(F)(F)F)C(O)C1O. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| TAK-285 | TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity[1]. TAK-285 can cross the blood-brain barrier (BBB)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 871026-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15196. | |
| TAK-418 | TAK-418 is a selective, orally active LSD1 (KDM1A) enzyme inhibitor with an IC50 of 2.9 nM. TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1818252-53-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-138830. | |
| TAK-438 | TAK-438 Inhibitor. Uses: Scientific use. Product Category: T2404. CAS No. 1260141-27-2. | |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Alternative Names: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grades: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. | |
| TAK-448 | TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MVT-602. CAS No. 1234319-68-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0076. | |
| TAK-448 acetate | TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MVT-602 acetate. CAS No. 1470374-22-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0076A. | |
| TAK-448 acetate | It is an agonist of KISS1R protein, and is an oligopeptide analogue of kisspeptin. Alternative Names: MVT-602 (acetate); Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg (Me)-Trp-NH2 acetate; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide acetate (1:1). Grades: ≥98%. CAS No. 1470374-22-1. Molecular formula: C58H80N16O14.C2H4O2. Mole weight: 1285.41. | |
| TAK-593 | TAK-593 is a potent VEGFR and PDGFR family inhibitor with IC50s of 3.2, 0.95, 1.1, 4.3 and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα and PDFGRβ, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1005780-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15506. | |
| TAK-615 | TAK-615 is a negative allosteric modulator (NAM) of the LPA1 receptor for the research of pulmonary fibrosis. TAK-615 binds the LPA1 receptor with high affinity (Kd high affinity of 1.7 nM and Kd low affinity of 14.5 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1664335-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117959. | |
| TAK-632 | TAK-632 is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAFV600E, BRAFWT, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228591-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15767. | |
| TAK 715 | TAK 715. Group: Biochemicals. Grades: Purified. CAS No. 303162-79-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TAK-715 | TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303162-79-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10456. | |
| TAK-733 | TAK-733 is a potent and selective MEK allosteric site inhibitor with an IC50 of 3.2 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1035555-63-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13449. | |
| TAK-779 | TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Takeda 779. CAS No. 229005-80-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13406. | |
| Tak875 | Tak875. Alternative Names: TAK875;3-Benzofuranacetic acid, 6-[[2,6-diMethyl-4-[3-(Methylsulfonyl)propoxy][1,1-biphenyl]-3-yl]Methoxy]-2,3-dihydro-, (3S)-;(3S)-6-[[2,6-Dimethyl-4-[3-(methylsulfonyl)propoxy][1,1-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid;TAK-875,TAK875;[(3S)-6-({2,6-Dimethyl-4-[3-(methylsulfonyl)propoxy]-3-biphenylyl}methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid;(S)-2-(6-((2,6-Dimethyl-4-(3-(methylsulfonyl)propoxy)-[1,1-biphenyl]-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid;TAK-875, >=98%;Fasiglifam. CAS No. 1000413-72-8. Purity: 99%+. Product ID: ACM1000413728. Molecular formula: C29H32O7S. Mole weight: 524.62518. IUPAC Name: 2-[(3S)-6-[[3-[2,6-dimethyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methoxy]-2,3-dihydro-1-benzofuran-3-yl]aceticacid. Canonical SMILES: CC1=CC(=CC(=C1C2=CC(=CC=C2)COC3=CC4=C(C=C3)C(CO4)CC(=O)O)C)OCCCS(=O)(=O)C. Alfa Chemistry - ISO 9001:32057 Certified. | |
| TAK-875 | TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist, with a pharmacokinetic profile enabling long-acting drug efficacy. Alternative Names: TAK875; TAK 875; Fasiglifam; 3-Benzofuranacetic acid, 6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-, (3S)-; (3S)-6-[[2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid; (+)-TAK 875; (3S)-6-([2',6'-Dimethyl-4'-[3-(methylsulfonyl)propoxy]biphenyl-3-yl]methoxy)-2,3-dihydro-1-benzofuran-3-yl]acetic acid. Grades: >98%. CAS No. 1000413-72-8. Molecular formula: C29H32O7S. Mole weight: 524.63. | |
| TAK-901 | TAK-901. Group: Biochemicals. Alternative Names: 5-[3-(Ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide. Grades: Highly Purified. CAS No. 934541-31-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H32N4O3S. US Biological Life Sciences. | Worldwide |
| TAK-901 | TAK-901 is a multi-targeted aurora inhibitor with IC50s of 21 and 15 nM for aurora A and B, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 934541-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12201. | |
| TAK-915 | TAK-915 is a potent, selective, brain-penetrant and orally active phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0.61 nM. TAK-915 is >4100-fold more selectivity for PDE2A than PDE1A. TAK-915 has the potential for neuropsychiatric and neurodegenerative disorders treatment[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1476727-50-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103493. | |
| TAK-960-d3 | TAK-960-d3. Group: Biochemicals. Alternative Names: 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: CH31D3F3N7O3, Molecular Weight: 564.62. US Biological Life Sciences. | Worldwide |
| TAK 960 hydrochloride | TAK 960 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1137868-96-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Takanawaene A | Takanawaene A is a pentaene macrolide antibiotic produced by Streptomyces sp. K99-5278. It inhibits the growth of Saccharomyces cerevisiae with IC50 of 21.8 μmol/L. Alternative Names: Fungicide K 99-5278A. CAS No. 627509-56-2. Molecular formula: C30H48O8. Mole weight: 536.70. | |
| Takanawaene B | Takanawaene B is a pentaene macrolide antibiotic produced by Streptomyces sp. K99-5278. It has the activity of inhibiting the growth of Aspergillus niger, Mucor raceme, Candida albicans and Saccharomyces cerevisiae, with IC50 of 0.94, 44.3, 177.0 and 20.9 μmol/L, respectively. CAS No. 627509-57-3. Molecular formula: C32H52O8. Mole weight: 564.75. | |
| Takanawaene C | Takanawaene C is a pentaene macrolide antibiotic produced by Streptomyces sp. K99-5278. It inhibits the growth of Saccharomyces cerevisiae with IC50 of 28.7 μmol/L. CAS No. 627509-58-4. Molecular formula: C33H54O8. Mole weight: 578.77. | |
| Takinib | Takinib Inhibitor. Uses: Scientific use. Product Category: T4264. CAS No. 1111556-37-6. | |
| Takinib | Takinib (EDHS-206) is an orally active and selective TAK1 inhibitor (IC50=9.5 nM), more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib is an inhibitor of autophosphorylated TAK1 that non-competitively binds within the ATP binding pocket. Takinib induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is also a P. falciparum protein kinase 9 (PfPK9) inhibitor (KD(app) of 0.46 μM)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EDHS-206. CAS No. 1111556-37-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103490. | |
| Talabostat mesylate | Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. Uses: For research used only. Alternative Names: (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid methanesulfonic acid (1:1); PT-100; PT100; PT 100; D05989; D-05989; D 05989; Val-boro-pro; Talabostat. Grades: 98%. CAS No. 150080-09-4. Molecular formula: C10H23BN2O6S. Mole weight: 310.17. | |
| Talabostat mesylate | Talabostat mesylate (Val-boroPro mesylate; PT100 mesylate) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM), inhibits DPP8/9 (IC50 = 4/11 nM; Ki = 1.5/0.76 nM), quiescent cell proline dipeptidase (QPP) (IC50 = 310 nM), DPP2, and some other DASH family enzymes. Antineoplastic and hematopoiesis- stimulating activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Val-boroPro mesylate; PT100 mesylate. CAS No. 150080-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13233A. | |
| Talabostat (Val-boroPro, PT-100) Mesylate | Talabostat (Val-boroPro, PT-100) is a dipeptidyl peptidase inhibitor with IC50 values of <4 nM, 4 nM, 11 nM, 310 nM, 560 nM and 390 nM for DPP-IV, DPP8, DPP9, QPP, FAP and PEP respectively. It has antineoplastic and hematopoiesis- stimulating activities. Group: Inhibitors. Alternative Names: Val-boroPro. CAS No. 150080-09-4. Pack Sizes: 5mg. Product ID: S8455. Formula: C10H23BN2O6S. Smiles: B(C1CCCN1C(=O)C(C(C)C)N)(O)O.CS(=O)(=O)O. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Talacotuzumab | Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has KDs of 0.43 nM, 188 nM, 46 nM, 16.8 nM for CD123, CD32b/c, CD16-158F, CD16-158V, respectively. Talacotuzumab inhibits IL-3 binding to CD123, antagonizing IL-3 signaling in target cells. Talacotuzumab has mutated the Fc region to increase affinity for CD16 (FcγRIIIa), thereby enhancing antibody-dependent cell-mediated cytotoxicity (ADCC). Talacotuzumab is highly effective in vivo reducing leukemic cell growth in acute myeloid leukemia (AML) xenograft mouse models[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ 56022473; CSL 362. CAS No. 1826831-79-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99395. | |
| Taladegib | Taladegib (LY2940680) is an antagonist of the smoothened receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY2940680. CAS No. 1258861-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13242. | |
| Talampanel | Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity[1]. Talampanel (IVAX) has neuroprotective effects in rodent stroke models[2]. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GYKI-53773; LY-300164. CAS No. 161832-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15079. | |
| Talampanel | Talampanel. Group: Biochemicals. Grades: Purified. CAS No. 161832-65-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Talaporfin sodium | Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ME2906; Mono-L-aspartyl chlorin e6; NPe6. CAS No. 220201-34-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16477. | |
| Talarozole | Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R115866. CAS No. 201410-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14531. | |
| Talarozole (Standard) | Talarozole (Standard) is the analytical standard of Talarozole. This product is intended for research and analytical applications. Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) which increases intracellular levels of endogenous all-trans retinoic acid (RA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R115866 (Standard). CAS No. 201410-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14531R. | |
| Talatisamine | Talatisamine inhibits the enhanced I(K) caused by Aβ40 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. Alternative Names: 20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol. Grades: 95 % (HPLC). CAS No. 20501-56-8. Molecular formula: C24H39NO5. Mole weight: 421.57. | |
| Talatisamine | Talatisamine. Group: Biochemicals. Alternative Names: Talatizamine. Grades: Plant Grade. CAS No. 20501-56-8. Pack Sizes: 10mg. Molecular Formula: C24H39NO5, Molecular Weight: 421.57. US Biological Life Sciences. | Worldwide |
| Talazoparib | Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMN-673; LT-673. CAS No. 1207456-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16106. | |
| Talazoparib | Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Uses: For research used only. Alternative Names: BMN-673; LT-673. BMN 673; LT 673. BMN673; LT673. Grades: 98%. CAS No. 1207456-01-6. Molecular formula: C19H14F2N6O. Mole weight: 380.359. | |
| Talazoparib | Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM). Category: Active pharmaceutical ingredients. CAS No. 1207456-01-6. Product ID: API1207456016. Molecular formula: C19H14F2N6O. Mole weight: 380.35. |  |
| Talazoparib tosylate | Talazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMN 673ts. CAS No. 1373431-65-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-108413. | |
| Talazoparib tosylate | Talazoparib tosylate (BMN 673ts) is an orally active and highly potent PARP1/2 inhibitor with antitumor activity for the study of specific breast cancers. Category: Active pharmaceutical ingredients. CAS No. 1373431-65-2. Product ID: API1373431652. Molecular formula: C26H22F2N6O4S. Mole weight: 552.55. | |
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