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| Product | Description | |
|---|---|---|
| JTE 907 | JTE 907. Group: Biochemicals. Grades: Purified. CAS No. 282089-49-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| JTE-907 | JTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 282089-49-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103325. |  |
| JTP10-TATi | JTP10-TATi is a selective inhibitor of JNK2 peptide. Grade: >95%. CAS No. 1293399-25-3. Molecular formula: C118H212N48O26. Mole weight: 2719.24. |  |
| JTT-501 | JTT-501. CAS No. 170861-63-9. Purity: 98%. Product ID: ACM170861639. Molecular formula: C22H20N2O5. Mole weight: 392.4. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| JTT 551 | JTT 551 is selective a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with Kis of 0.22 μM and 9.3 μM for PTP1B and TCPTP (T-cell protein tyrosine phosphatase), respectively; JTT 551 can be used in the research of type 2 diabetes mellitus. Uses: Scientific research. Category: Signaling pathways. CAS No. 776309-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19779. | |
| JTV 519 fumarate | JTV 519 fumarate. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JTV-519 hemifumarate | JTV-519 hemifumarate (K201 hemifumarate) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: K201 hemifumarate. CAS No. 1435938-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15293B. | |
| Juglalin | Juglalin. Group: Biochemicals. CAS No. 99882-10-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Juglomycin A | Juglomycin A is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (-)-Juglomycin A; 1,4-Naphthalenedione,5-hydroxy-2-[(2R,3R)-tetrahydro-3-hydroxy-5-oxo-2-furanyl]-. CAS No. 38637-88-6. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| Juglomycin B | Juglomycin B is originally isolated from Str. distatochromogenes var. juglonensis 190-2. It has a broad spectrum of antibacterial and mycobacterial effects, and has the effect of inhibiting ehrlician ascites cancer in mice and prolongating life with 1 mg/kg. Synonyms: (+/-)-juglomycin A. CAS No. 38637-89-7. Molecular formula: C14H10O6. Mole weight: 274.22. | |
| juglone 3-monooxygenase | Also acts on 1,4-naphthoquinone, naphthazarin and 2-chloro-1,4-naphthoquinone, but not on other related compounds. Group: Enzymes. Synonyms: juglone hydroxylase; naphthoquinone hydroxylase; naphthoquinone-hydroxylase. Enzyme Commission Number: EC 1.14.99.27. CAS No. 98865-54-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1044; juglone 3-monooxygenase; EC 1.14.99.27; 98865-54-4; juglone hydroxylase; naphthoquinone hydroxylase; naphthoquinone-hydroxylase. Cat No: EXWM-1044. |  |
| Jujube | Jujube. |  |
| Jujube extract | Jujube extract. Applications: Jujube extract can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Purity: 10:1 20:1. Appearance: Brown powder. Source: Ziziphus jujuba, commonly called jujube, sometimes jujuba, red date, Chinese date, Korean date, or Indian date is a species of Ziziphus in the buckthorn family (Rhamnaceae). It is used primarily as a shade tree that also bears fruit. Jujube extract; Fructus Jujubae. Cat No: EXTC-189. | |
| Jujube Seed Extract | Jujube seed extract is prepared from the natural plant of Semen Ziziphi Spinosae, which is traditional Chinese herb. Jujube seed extract contains jujuboside A, jujuboside B, betulinic acid, betulin and ect. Jujube seed extract was used to soothe the nerves, stop sweating, nourish the heart, benefit the liver, treat insomnia, tranquilize the mind. Group: Others. Mole weight: 1207.35. Jujube Seed Extract; Ziziphus Jujuba Mill. Cat No: EXTC-011. | |
| Jujube Seed Powder & Berry P.E. 20:1 | Jujube Seed Powder & Berry P.E. 20:1. |  CA, FL & NJ |
| Jujuboside A | Jujuboside A may serve as a potential therapeutic agent for the treatment of Alzheimer?s disease. Uses: Therapeutic agent. Synonyms: α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-; (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside. Grade: >98%. CAS No. 55466-04-1. Molecular formula: C58H94O26. Mole weight: 1207.35. | |
| Jujuboside A | Jujuboside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 55466-04-1. Pack Sizes: 20mg. Molecular Formula: C58H94O26, Molecular Weight: 1207.35. US Biological Life Sciences. | Worldwide |
| Jujuboside A | Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety. Uses: Scientific research. Category: Signaling pathways. CAS No. 55466-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0659. | |
| Jujuboside B | Jujuboside B. Group: Biochemicals. Grades: Plant Grade. CAS No. 55466-05-2. Pack Sizes: 20mg. Molecular Formula: C52H84O21, Molecular Weight: 1045.21. US Biological Life Sciences. | Worldwide |
| Jujuboside B1 | Jujuboside B1. Group: Biochemicals. Grades: Plant Grade. CAS No. 68144-21-8. Pack Sizes: 10mg. Molecular Formula: C52H84O21, Molecular Weight: 1045.21. US Biological Life Sciences. | Worldwide |
| Jujuboside D | Botanical Source: Group: Biochemicals. Alternative Names: Jujuboside A1. Grades: Plant Grade. CAS No. 194851-84-8. Pack Sizes: 10mg, 20mg. US Biological Life Sciences. | Worldwide |
| Julimycin B2 | Julimycin B2 is originally isolated from Str. shiodaensis. It has anti-gram-positive bacteria and anti-virus activity and it has effects on ehrman ascites carcinoma in mice of 3.10-12.5 mg/kg. Synonyms: Julimycin II; JULIMYCIN B2-CA; Julimycin B-II; (2,2'-Bianthracene)-8,8',9,9',10,10'(5H,5'H)-hexone, 6,6',7,7'-tetrahydro-1,1',6-beta,6'-beta-tetrahydroxy-5-beta,5'-beta-bis(1-hydroxyethyl)-6,6'-dimethyl-,5,5'-diacetate. Grade: >98%. CAS No. 18126-05-1. Molecular formula: C38H34O14. Mole weight: 714.67. | |
| Julolidine | Julolidine. Alternative Names: 2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizine. CAS No. 479-59-4. Molecular formula: C12H15N. Mole weight: 173.25. IUPAC Name: 1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene. SMILES: C1CN2CCCc3cccc(C1)c23. InChI: 1S/C12H15N/c1-4-10-6-2-8-13-9-3-7-11(5-1)12(10)13/h1,4-5H,2-3,6-9H2,DZFWNZJKBJOGFQ-UHFFFAOYSA-N. | |
| jump Start 12V vehicle. | jump Start 12V vehicle. | |
| JUN68744 | JUN68744 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. Synonyms: JUN-68744; JUN 68744; PSMA-617-linker; PSMA 617-linker; PSMA617-linker; Vipivotide tetraxetan Linker; (((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid. CAS No. 1703768-74-4. Molecular formula: C33H45N5O9. Mole weight: 655.74. | |
| Juncuenin D | Juncuenin D, an all-natural compound, boasts of its potent anti-inflammatory and anticancer properties. Research studies exhibit its capability to suppress leukemia cells' growth via selective cell cycle arrest. Furthermore, it showcases its therapeutic potential in terms of inflammatory diseases by impeding pro-inflammatory cytokine production. Its revolutionary features highlight its significance as a potential therapeutic agent with immense curative measures. Synonyms: Juncuenin D; 1161681-24-8; SCHEMBL23764926; HY-N8464; AKOS040762871; CS-0144572; F94140. Grade: 97.5%. CAS No. 1161681-24-8. Molecular formula: C18H18O3. Mole weight: 282.339. | |
| Juncusol | Juncusol is a 9,10-dihydrophrenathrene found in Juncus species with antimicrobial activity against Bacillus subtilis and Staphylococcus aureus. Synonyms: 1,6-dimethyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol; 5-ethenyl-1,6-dimethyl-9,10-dihydrophenanthrene-2,7-diol. Grade: >98%. CAS No. 62023-90-9. Molecular formula: C18H18O2. Mole weight: 266.34. | |
| Juncutol | Juncutol, a topical antiseptic, exerts its antimicrobial effect through the active ingredient, povidone-iodine, which eradicates bacteria and other microorganisms that may cause infections in cuts, wounds, and burns. In addition to this primary indication, it has been employed for the management of chronic wounds, including diabetic foot ulcers. With its proven efficacy and safety profile, Juncutol is an indispensable tool in wound care. Synonyms: Juncutol; 1021950-14-0; AKOS040762876; HY-133098; CS-0110687; F94141. Grade: 98.0%. CAS No. 1021950-14-0. Molecular formula: C18H18O2. Mole weight: 266.34. | |
| Juniper Berry Oil | Juniper Berry Oil. CAS No. 8002-68-4. FEMA No. 2604. Kosher: Y. VIGON Item # 501405. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. |  America & Internationally |
| Jurkat Electroporation Kit | Electroporation buffer optimized for Jurkat T-cell leukemia cells. Optimized electroporation protocol provided for transfection of si/miRNA, DNA, mRNA, and small proteins. Feature high transfection efficacy and cell viability. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 6568. |  Nevada, Texas, USA |
| Justicidin A | justicidin A is a nature product that could be isolated form Justicia procumbens. justicidin A decreases the level of Ku70 leading to translocation of Bax from the cytosol to mitochondria to induce apoptosis. justicidin A can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25001-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-117078. | |
| Justicidin B | Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 17951-19-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114275. | |
| juvenile-hormone esterase | Demethylates the insect juvenile hormones JH1 and JH3, but does not hydrolyse the analogous ethyl or isopropyl esters. Group: Enzymes. Synonyms: JH-esterase; juvenile hormone analog esterase; juvenile hormone carboxyesterase; methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase. Enzyme Commission Number: EC 3.1.1.59. CAS No. 50812-15-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3487; juvenile-hormone esterase; EC 3.1.1.59; 50812-15-2; JH-esterase; juvenile hormone analog esterase; juvenile hormone carboxyesterase; methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase. Cat No: EXWM-3487. | |
| Juvenile hormone III | Juvenile hormone III. CAS No: 24198-95-6 |  Sarchem Laboratories New Jersey NJ |
| juvenile hormone-III synthase | The enzyme, found in insects, is involved in the synthesis of juvenile hormone III, a sesquiterpenoid that regulates several processes including embryonic development, metamorphosis, and reproduction, in many insect species. Group: Enzymes. Synonyms: farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Enzyme Commission Number: EC 2.1.1.325. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1933; juvenile hormone-III synthase; EC 2.1.1.325; farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Cat No: EXWM-1933. | |
| Juvenimicin A2 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A2 can resist gram-positive bacteria and individual gram-negative bacteria. Synonyms: BRN 1413776; 6-De(2-oxoethyl)-4'-deoxy-6-methylcirramycin A1. CAS No. 61417-47-8. Molecular formula: C30H51NO8. Mole weight: 553.73. | |
| Juvenimicin A3 | It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A3 can resist gram-positive bacteria and individual gram-negative bacteria. Synonyms: Rosaramicin; Rosaramicina; Rosaramicine; Rosaramicinum; Antibiotic 67-694; NSC 175150; 3-Ethyl-7-hydroxy-2,8,12,16-tetramethyl-5,13-dioxo-9-((3,4,6-tridesoxy-3-dimethylamino-beta-O-xylo-hexopyranosyl)oxy)-4,17-dioxabicyclo(14.1.0)heptadec-14-en-10-acetaldehyd. CAS No. 35834-26-5. Molecular formula: C31H51NO9. Mole weight: 581.74. | |
| JW 133 (10mg/mL in Methyl Acetate) | JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC analogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 259869-55-1. Pack Sizes: 100ul, 1mL. Molecular Formula: C22H32O. US Biological Life Sciences. | Worldwide |
| JW480 | JW480 is a selective KIAA1363/AADACL1 inhibitor with oral activity, featuring IC50 values of 12 nM against human KIAA1363, 20 nM against mouse KIAA1363. JW480 blocks lipid deacetylase activity to restrain HAG metabolism and lowers retinyl ester hydrolase function in hepatic stellate cells. JW480 reduces MAGE lipid levels and inhibits migration, invasion, survival and tumor growth of prostate cancer cells. JW480 lowers PKCδ phosphorylation, facilitates HAGP accumulation, diminishes platelet aggregation, dense granule secretion and Ca2+ flux, delays arterial thrombosis and prolongs tail bleeding time in rats. JW480 can be used for the study of prostate cancer and thrombosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354359-53-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107582. | |
| JW 55 | JW 55. Group: Biochemicals. Grades: Purified. CAS No. 664993-53-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JW67 | JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM[1]. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 442644-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108442. | |
| JW 67 | JW 67. Group: Biochemicals. Grades: Purified. CAS No. 442644-28-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JW74 | JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling with an IC50 of 420 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 863405-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19739. | |
| JWG-071 | JWG-071 is the kinase-selective chemical probe for ERK5. JWG-071 inhibits ERK5 and LRRK2 with IC50 values of 88nM and 109 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250323-50-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108886. | |
| JWH-018 4-Hydroxypentyl metabolite solution | JWH-018 4-Hydroxypentyl metabolite solution. Uses: For analytical and research use. CAS No. 1320363-47-0. Mole weight: 357.44. EC Number: 200-659-6. Catalog: AP1320363470. |  |
| JWH-018 6-Hydroxyindole | JWH-018 6-Hydroxyindole is a metabolite of JWH 018 (P283650) which acts as a cannabinoid receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1307803-44-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C24H23NO2, Molecular Weight: 357.44. US Biological Life Sciences. | Worldwide |
| JWH-019 5-Hydroxyhexyl metabolite solution | JWH-019 5-Hydroxyhexyl metabolite solution. Uses: For analytical and research use. CAS No. 1435934-47-6. Mole weight: 371.47. EC Number: 200-659-6. Catalog: AP1435934476. | |
| JWH-019 6-Hydroxyhexyl metabolite solution | JWH-019 6-Hydroxyhexyl metabolite solution. Uses: For analytical and research use. CAS No. 1435934-29-4. Mole weight: 371.47. EC Number: 200-659-6. Catalog: AP1435934294. | |
| JWH-073 4-Butanoic acid metabolite solution | JWH-073 4-Butanoic acid metabolite solution. Uses: For analytical and research use. CAS No. 1307803-52-6. Mole weight: 357.40. EC Number: 200-659-6. Catalog: AP1307803526. | |
| JWH 073 6-Methoxyindole | JWH 073 6-Methoxyindole. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C24H23NO2, Molecular Weight: 357.5. US Biological Life Sciences. | Worldwide |
| JWH 073 N-(4-Hydroxybutyl) β-D-Glucuronide | JWH 073 N-(4-Hydroxybutyl) β-D-Glucuronide. Group: Biochemicals. Alternative Names: 4-[3-(1-Naphthalenylcarbonyl)-1H-indol-1-yl]butyl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C29H31NO7, Molecular Weight: 505.56. US Biological Life Sciences. | Worldwide |
| JWH-122 (Indole-d5) 5-Hydroxypentyl | JWH-122 (Indole-d5) 5-Hydroxypentyl is labelled JWH-122 5-Hydroxypentyl (J211465) which is a urinary metabolite of JWH-122. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D5NO2, Molecular Weight: 376.5. US Biological Life Sciences. | Worldwide |
| JWH-122 N-Pentanoic Acid-d4 | JWH-122 N-Pentanoic Acid-d4. Group: Biochemicals. Alternative Names: 5-Carboxy-JWH-122; 5-(3-(4-methyl-1-naphthoyl)-1H-indol-1-yl)pentanoic Acid-d4; MAM-2201 5-Pentanoic Acid-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H19D4NO3, Molecular Weight: 389.48. US Biological Life Sciences. | Worldwide |
| JWH-210 4-Hydroxypentyl metabolite-[d5] (indole-[d5]) | An isotope labelled metabolite of JWH210. JWH210 is a cannabimimetic alkylindole that has been identified in extracts from herbal blends. Grade: 95% by HPLC; 98% atom D. Molecular formula: C26H22D5NO2. Mole weight: 390.53. | |
| JWH-250 5-Hydroxypentyl metabolite solution | JWH-250 5-Hydroxypentyl metabolite solution. Uses: For analytical and research use. CAS No. 1427325-83-4. Mole weight: 351.44. EC Number: 200-659-6. Catalog: AP1427325834. | |
| JWZ-5-13 | JWZ-5-13 is a CDK7 PROTAC degrader. JWZ-5-13 inhibits the proliferation of cancer cells. JWZ-5-13 is applicable to the research of ovarian cancer, diffuse large B-cell lymphoma, acute T-lymphoblastic leukemia and non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3103763-70-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161828. | |
| JX06 | JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 729-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19564. | |
| JX 401 | JX 401. Group: Biochemicals. Grades: Purified. CAS No. 349087-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| JY-2 | JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 339103-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153347. | |
| JYQ-164 | JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117543-49-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163562. | |
| JYQ-173 | JYQ-173, a chemical probe, is a selective inhibitor for human Parkinson disease protein 7 (PARK7), with an IC50 of 19 nM. JYQ-173 exhibits good cell permeability. JYQ-173 is the ligand for target protein PARK7, which can be utilized for synthesis of PROTAC Degrader JYQ-194 (HY-163564)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117543-57-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163563. | |
| JZL 184 | JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1101854-58-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15249. | |
| JZL 195 | JZL 195. Group: Biochemicals. Grades: Purified. CAS No. 1210004-12-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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