A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Juncusol is a 9,10-dihydrophrenathrene found in Juncus species with antimicrobial activity against Bacillus subtilis and Staphylococcus aureus. Alternative Names: 1,6-dimethyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol; 5-ethenyl-1,6-dimethyl-9,10-dihydrophenanthrene-2,7-diol. Grades: >98%. CAS No. 62023-90-9. Molecular formula: C18H18O2. Mole weight: 266.34.
Juncutol
Juncutol, a topical antiseptic, exerts its antimicrobial effect through the active ingredient, povidone-iodine, which eradicates bacteria and other microorganisms that may cause infections in cuts, wounds, and burns. In addition to this primary indication, it has been employed for the management of chronic wounds, including diabetic foot ulcers. With its proven efficacy and safety profile, Juncutol is an indispensable tool in wound care. Alternative Names: Juncutol; 1021950-14-0; AKOS040762876; HY-133098; CS-0110687; F94141. Grades: 98.0%. CAS No. 1021950-14-0. Molecular formula: C18H18O2. Mole weight: 266.34.
Junicedric acid
Junicedric acid is extracted from the fronds of Dicranopteris linearis or D. ampla. It shows gastroprotective effects. Alternative Names: Mercusic acid; 13S-Dihydroagathic acid; (1S,4aR,5S,8aR)-5-[(3S)-4-carboxy-3-methylbutyl]-1,4a-dimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalene-1-carboxylic acid. CAS No. 41787-69-3. Molecular formula: C20H32O4. Mole weight: 336.47.
Electroporation buffer optimized for Jurkat T-cell leukemia cells. Optimized electroporation protocol provided for transfection of si/miRNA, DNA, mRNA, and small proteins. Feature high transfection efficacy and cell viability. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 6568.
Nevada, Texas, USA
Justicidin A
justicidin A is a nature product that could be isolated form Justicia procumbens. justicidin A decreases the level of Ku70 leading to translocation of Bax from the cytosol to mitochondria to induce apoptosis. justicidin A can be used in research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25001-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-117078.
Justicidin B
Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 17951-19-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114275.
juvenile-hormone esterase
Demethylates the insect juvenile hormones JH1 and JH3, but does not hydrolyse the analogous ethyl or isopropyl esters. Group: Enzymes. Synonyms: JH-esterase; juvenile hormone analog esterase; juvenile hormone carboxyesterase; methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase. Enzyme Commission Number: EC 3.1.1.59. CAS No. 50812-15-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3487; juvenile-hormone esterase; EC 3.1.1.59; 50812-15-2; JH-esterase; juvenile hormone analog esterase; juvenile hormone carboxyesterase; methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase. Cat No: EXWM-3487.
The enzyme, found in insects, is involved in the synthesis of juvenile hormone III, a sesquiterpenoid that regulates several processes including embryonic development, metamorphosis, and reproduction, in many insect species. Group: Enzymes. Synonyms: farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Enzyme Commission Number: EC 2.1.1.325. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1933; juvenile hormone-III synthase; EC 2.1.1.325; farnesoic acid methyltransferase; juvenile hormone acid methyltransferase; JHAMT. Cat No: EXWM-1933.
Juvenimicin A2
It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A2 can resist gram-positive bacteria and individual gram-negative bacteria. Alternative Names: BRN 1413776; 6-De(2-oxoethyl)-4'-deoxy-6-methylcirramycin A1. CAS No. 61417-47-8. Molecular formula: C30H51NO8. Mole weight: 553.73.
Juvenimicin A3
It is produced by the strain of Micromono spora chalcea var. izumensis. Juvenimicin A3 can resist gram-positive bacteria and individual gram-negative bacteria. Alternative Names: Rosaramicin; Rosaramicina; Rosaramicine; Rosaramicinum; Antibiotic 67-694; NSC 175150; 3-Ethyl-7-hydroxy-2,8,12,16-tetramethyl-5,13-dioxo-9-((3,4,6-tridesoxy-3-dimethylamino-beta-O-xylo-hexopyranosyl)oxy)-4,17-dioxabicyclo(14.1.0)heptadec-14-en-10-acetaldehyd. CAS No. 35834-26-5. Molecular formula: C31H51NO9. Mole weight: 581.74.
JW 133 (10mg/mL in Methyl Acetate)
JW 133 is an intermediate used to synthesize potent CB2-Selective Cannabinoid Receptor Ligands such as 4-oxo-1,4-dihydroquinoline-3-carboxamides and 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC analogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 259869-55-1. Pack Sizes: 100ul, 1mL. Molecular Formula: C22H32O. US Biological Life Sciences.
Worldwide
JW480
JW480 is a selective KIAA1363/AADACL1 inhibitor with oral activity, featuring IC50 values of 12 nM against human KIAA1363, 20 nM against mouse KIAA1363. JW480 blocks lipid deacetylase activity to restrain HAG metabolism and lowers retinyl ester hydrolase function in hepatic stellate cells. JW480 reduces MAGE lipid levels and inhibits migration, invasion, survival and tumor growth of prostate cancer cells. JW480 lowers PKCδ phosphorylation, facilitates HAGP accumulation, diminishes platelet aggregation, dense granule secretion and Ca2+ flux, delays arterial thrombosis and prolongs tail bleeding time in rats. JW480 can be used for the study of prostate cancer and thrombosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354359-53-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107582.
JW 55
JW 55. Group: Biochemicals. Grades: Purified. CAS No. 664993-53-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
JW67
JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM[1]. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 442644-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108442.
JW 67
JW 67. Group: Biochemicals. Grades: Purified. CAS No. 442644-28-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
JW74
JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling with an IC50 of 420 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 863405-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19739.
JWG-071
JWG-071 is the kinase-selective chemical probe for ERK5. JWG-071 inhibits ERK5 and LRRK2 with IC50 values of 88nM and 109 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250323-50-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108886.
JWH-018 4-Hydroxypentyl metabolite solution
JWH-018 4-Hydroxypentyl metabolite solution. Uses: For analytical and research use. CAS No. 1320363-47-0. Mole weight: 357.44. EC Number: 200-659-6. Catalog: AP1320363470.
JWH-018 6-Hydroxyindole
JWH-018 6-Hydroxyindole is a metabolite of JWH 018 (P283650) which acts as a cannabinoid receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1307803-44-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C24H23NO2, Molecular Weight: 357.44. US Biological Life Sciences.
Worldwide
JWH-019 5-Hydroxyhexyl metabolite solution
JWH-019 5-Hydroxyhexyl metabolite solution. Uses: For analytical and research use. CAS No. 1435934-47-6. Mole weight: 371.47. EC Number: 200-659-6. Catalog: AP1435934476.
JWH-019 6-Hydroxyhexyl metabolite solution
JWH-019 6-Hydroxyhexyl metabolite solution. Uses: For analytical and research use. CAS No. 1435934-29-4. Mole weight: 371.47. EC Number: 200-659-6. Catalog: AP1435934294.
JWH-073 4-Butanoic acid metabolite solution
JWH-073 4-Butanoic acid metabolite solution. Uses: For analytical and research use. CAS No. 1307803-52-6. Mole weight: 357.40. EC Number: 200-659-6. Catalog: AP1307803526.
JWH 073 N-(4-Hydroxybutyl) β-D-Glucuronide. Group: Biochemicals. Alternative Names: 4-[3-(1-Naphthalenylcarbonyl)-1H-indol-1-yl]butyl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C29H31NO7, Molecular Weight: 505.56. US Biological Life Sciences.
Worldwide
JWH-122 (Indole-d5) 5-Hydroxypentyl
JWH-122 (Indole-d5) 5-Hydroxypentyl is labelled JWH-122 5-Hydroxypentyl (J211465) which is a urinary metabolite of JWH-122. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H20D5NO2, Molecular Weight: 376.5. US Biological Life Sciences.
Worldwide
JWH-122 N-Pentanoic Acid-d4
JWH-122 N-Pentanoic Acid-d4. Group: Biochemicals. Alternative Names: 5-Carboxy-JWH-122; 5-(3-(4-methyl-1-naphthoyl)-1H-indol-1-yl)pentanoic Acid-d4; MAM-2201 5-Pentanoic Acid-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C25H19D4NO3, Molecular Weight: 389.48. US Biological Life Sciences.
Worldwide
JWH-250 5-Hydroxypentyl metabolite solution
JWH-250 5-Hydroxypentyl metabolite solution. Uses: For analytical and research use. CAS No. 1427325-83-4. Mole weight: 351.44. EC Number: 200-659-6. Catalog: AP1427325834.
JWZ-5-13
JWZ-5-13 is a CDK7 PROTAC degrader. JWZ-5-13 inhibits the proliferation of cancer cells. JWZ-5-13 is applicable to the research of ovarian cancer, diffuse large B-cell lymphoma, acute T-lymphoblastic leukemia and non-small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3103763-70-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161828.
JX06
JX06 is a potent, selective and covalent inhibitor of PDK. JX06 inhibits PDK1, PDK2 and PDK3 with IC50s of 49 nM, 101 nM, and 313 nM, respectively. JX06 inhibits PDK1 activity via covalently binding to a cysteine residue in an irreversible manner. JX06 shows significant antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 729-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19564.
JX 06
JX 06 is a potent, selective and covalent pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor with IC50 values of 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively. It suppresses A549 lung cancer cell proliferation in vitro and reduces tumor volume of A549 xenografts in mice. Alternative Names: JX-06; JX06; Bis(morpholinothiocarbonyl) Disulfide; 4,4'-(Dithiodicarbonothioyl)bis[morpholine]; 4-Morpholinethiocarbonyl Disulfide; Dimorpholinethiuram Disulfide; Disulfide, bis(4-Morpholinylthioxomethyl); NSC 402538; bis(Oxydi-2,1-ethanediyl)-thiuram Disulfide. Grades: ≥98% by HPLC. CAS No. 729-46-4. Molecular formula: C10H16N2O2S4. Mole weight: 324.51.
JX 401
JX 401. Group: Biochemicals. Grades: Purified. CAS No. 349087-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
JY-2
JY-2. CAS No. 339103-05-8.
JY-2
JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 339103-05-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153347.
JYQ-164
JYQ-164 is a small molecule inhibitor of Parkinson's disease protein 7 (PARK7/DJ-1) in humans. JYQ-164 works by covalently and selectively targeting Cys106, a key residue of PARK7 (IC50=21 nM). The high inhibitory effect of JYQ-164 on PARK7 is 5 times more potent than the previously reported inhibitor JYQ-88. JYQ-164 can be used in Parkinson's disease and cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117543-49-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163562.
JYQ-173
JYQ-173, a chemical probe, is a selective inhibitor for human Parkinson disease protein 7 (PARK7), with an IC50 of 19 nM. JYQ-173 exhibits good cell permeability. JYQ-173 is the ligand for target protein PARK7, which can be utilized for synthesis of PROTAC Degrader JYQ-194 (HY-163564)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117543-57-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163563.
JZL 184
JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1101854-58-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15249.
JZL195
JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. IC50 values are 2 nM for MAGL and 4 nM for FAAH. JZL195 has been shown to inhibit endocannabinoid hydrolysis and elevate 2-AG and AEA levels in vivo. Alternative Names: JZL195; JZL-195; JZL 195. Grades: >98%. CAS No. 1210004-12-8. Molecular formula: C24H23N3O5. Mole weight: 433.46.
JZL 195
JZL 195. Group: Biochemicals. Grades: Purified. CAS No. 1210004-12-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.