A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Jarin-1 | Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1212704-51-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115521. |  |
| Jasmacyclene | Jasmacyclene (Tricyclododecenyl Acetate, Cyclacet). CAS No. 5413-60-5. VIGON Item # 502504. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Jasmatone | Jasmatone. CAS No. 13074-65-2. VIGON Item # 503230. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasmin 231 | Jasmin 231. CAS No. MIXTURE. VIGON Item # 502804. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasmine Absolute India 100% Pure | Jasmine Absolute India 100% Pure. CAS No. 8022-96-6. FEMA No. 2600. Kosher: Y. VIGON Item # 503974. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils. | America & Internationally |
| Jasmine Fragrance Powder | Jasmine Fragrance Powder. |  CA, FL & NJ |
| Jasmine oil | Jasmine oil. Alternative Names: Jasmine flower oil. CAS No. 8022-96-6. Purity: 0.98. Product ID: CI-EO-0034. Molecular formula: C10H16. Mole weight: 136.23 g/mol. IUPAC Name: 1-but-2-enyl-2-methylcyclopentene. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Jasminin | Jasminin is extracted from the leaves of Jasminum primulinum HEMSL. It tastes bitter. Synonyms: 4-Ethylidene-3-(β-D-glucopyranosyloxy)-3,4,4a,5,9,10,11,12-octahydro-10-(2-hydroxy-1-methylethyl)-15-methyl-9,12-methano-6H,8H,14H-pyrano[3,4-c][1,7]dioxacyclododecin-6,14-dione. Grade: 98.5%. CAS No. 30164-93-3. Molecular formula: C26H38O12. Mole weight: 542.57. |  |
| Jasminoside B | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 214125-04-9. Pack Sizes: 5mg, 10mg, 20mg. US Biological Life Sciences. |  Worldwide |
| Jasmolactone | Jasmolactone. CAS No. 32764-98-0. FEMA No. 4441. Kosher: Y. VIGON Item # 502805. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasmolin II+ Cinerin II + Pyrethrin II (Mixture) | Jasmolin II+ Cinerin II + Pyrethrin II is a by-product from the purification of Pyrethrin 2 (~30%, Technical Grade) (P991240). Pyrethrin is a pesticide most commonly used around homes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g, 2.5g. Molecular Formula: C21H28O5; C22H30O5; C22H28O5. US Biological Life Sciences. | Worldwide |
| jasmonate O-methyltransferase | 9,10-Dihydrojasmonic acid is a poor substrate for the enzyme. The enzyme does not convert 12-oxo-phytodienoic acid (a precursor of jasmonic acid), salicylic acid, benzoic acid, linolenic acid or cinnamic acid into their corresponding methyl esters. Enzyme activity is inhibited by the presence of divalent cations, e.g., Ca2+, Cu2+, Mg2+ and Zn2+. Group: Enzymes. Synonyms: jasmonic acid carboxyl methyltransferase. Enzyme Commission Number: EC 2.1.1.141. CAS No. 346420-58-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1737; jasmonate O-methyltransferase; EC 2.1.1.141; 346420-58-4; jasmonic acid carboxyl methyltransferase. Cat No: EXWM-1737. |  |
| Jasmone Cis | Jasmone Cis. CAS No. 488-10-8. FEMA No. 3196. Kosher: Y. VIGON Item # 500192. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Jasmonic acid | Jasmonic acid ((-)-Jasmonic acid) is a plant growth regulator and a derivative of Linolenic acid (HY-N0728). Jasmonic acid enhances plant resistance and is widely used as a stress protectant. Jasmonic acid is an endogenous plant hormone and a plant growth inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Jasmonic acid. CAS No. 6894-38-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122464A. | |
| Jasmonic acid | Jasmonic acid. Alternative Names: (1R,2R)-2-[(Z)-2-Pentenyl]-3-oxocyclopentane-1-acetic acid. CAS No. 6894-38-8. Purity: >98.0%. Product ID: FFC-AR-6894388. Molecular formula: C12H18O3. Mole weight: 210.27. IUPAC Name: 2-[(1R,2R)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]acetic acid. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Jasmonyl ® | Jasmonyl ® (1,3-Nonane Diol Acetate). CAS No. 18871-14-2. Kosher: Y. VIGON Item # 500449. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers. | America & Internationally |
| Jasmopyrane Forte | Jasmopyrane Forte. CAS No. 18871-14-2. VIGON Item # 503232. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jasmorange® | Jasmorange® (Satinaldehyde). CAS No. 41496-43-9. FEMA No. 2748. Kosher: Y. VIGON Item # 503005. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. | America & Internationally |
| Jaspamycin | Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-CN-7-C-Ino. CAS No. 22242-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111759. | |
| Jasplakinolide | Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research. Source:Isolated from Jaspis splendens. Group: Biochemicals. Grades: Highly Purified. CAS No. 102396-24-7. Pack Sizes: 50ug, 100ug. Molecular Formula: C36H45BrN4O6. US Biological Life Sciences. | Worldwide |
| Jasplakinolide | Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 102396-24-7. Pack Sizes: 50 μg; 100 μg. Product ID: HY-P0027. | |
| Jatrophane 2 | Jatrophane 2 can be found in the branches of Jatropha carcas L. Synonyms: 2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6(17),11E-diene. Grade: >98%. CAS No. 210108-86-4. Molecular formula: C39H50O15. Mole weight: 758.8. | |
| Jatrophane 3 | Jatrophane 3 can be found in the branches of Jatropha carcas L. Synonyms: 2,5,14-Triacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxy-9-nicotinoyloxyjatropha-6(17),11E-diene. Grade: >98%. CAS No. 210108-87-5. Molecular formula: C43H53NO14. Mole weight: 807.9. | |
| Jatrophane 4 | Jatrophane 4 comes from the branches of Jatropha carcas L. Synonyms: 2,5,9,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-7-isobutyroyloxyjatropha-6(17),11E-diene. Grade: 95%. CAS No. 210108-88-6. Molecular formula: C39H52O14. Mole weight: 744.8. | |
| Jatrophane 5 | Jatrophane 5, coming from the branches of Jatropha carcas L, demonstrated the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR). Synonyms: 2,5,7,14-Tetraacetoxy-3-benzoyloxy-8,15-dihydroxy-9-nicotinoyloxyjatropha-6(17),11E-diene. Grade: >98%. CAS No. 210108-89-7. Molecular formula: C41H49NO14. Mole weight: 779.8. | |
| Jatrorrhizine | Botanical Source: Group: Biochemicals. Alternative Names: Neprotine, Yatrorizine, Jateorhizine, Dehydrocorypalmine. Grades: Plant Grade. CAS No. 3621-38-3. Pack Sizes: 20mg. US Biological Life Sciences. | Worldwide |
| Jatrorrhizine chloride | Jatrorrhizine chloride. Group: Biochemicals. Alternative Names: Neprotine chloride. Grades: Plant Grade. CAS No. 6681-15-8. Pack Sizes: 20mg. Molecular Formula: C20H20ClNO4, Molecular Weight: 373.83. US Biological Life Sciences. | Worldwide |
| Javanicin | It is produced by the strain of Fusarium javanicum, etc. Javanicin is resistant to gram-positive bacteria and mycobacteria. Synonyms: 5,8-Dihydroxy-6-methoxy-3-(2-oxopropyl)-1,4-naphthalenedione; 3-Acetonyl-5,8-dihydroxy-6-methoxy-2-methyl-1,4-naphthoquinone; BRN 2296055. Grade: ≥98% by HPLC. CAS No. 476-45-9. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Javanol ® | Javanol ®. CAS No. 198404-98-7. FEMA No. 4776. Kosher: Y. VIGON Item # 502361. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, sandal cyclopropane. | America & Internationally |
| Jawsamycin | It is produced by the strain of Streptoverticillium fervens. Jawsamycin had strong anti-filamentous fungal activity, and the MIC of Aspergillus Niger, Aureobasidium and Mucor was 0.05 μg/mL. Synonyms: FR-900848; FR900848. CAS No. 120500-69-8. Molecular formula: C32H43N3O6. Mole weight: 565.70. | |
| JB-1 | JB-1, an IGF-I analog, is a selective IGF-I receptor inhibitor that does not interact with IGF-II. JB-1 competes with IGF-I for binding to IGF-1R and blocks receptor autophosphorylation. JB-1 increases the level of sVEGFR-1. JB-1 normalizes retinal abnormalities, including reducing retinal neovascularization. JB-1 is applicable to studies related to oxygen-induced retinopathy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147819-32-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3226. | |
| JB170 | JB170 is a potent and highly specific PROTAC-mediated AURORA-A (Aurora Kinase) degrader (DC50=28 nM) by linking Alisertib, to the Cereblon-binding molecule Thalidomide. JB170 preferentially binds AURORA-A (EC50=193 nM) over AURORA-B (EC50=1.4 μM). JB170-mediated S-phase arrest is caused specifically by AURORA-A depletion. JB170 has excellent ability to inhibit non-catalytic function of AURORA-A kinase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2705844-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141512. | |
| JB-95 | JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1873323-60-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5753. | |
| JBI-589 | JBI-589 is a non-covalent PAD4 isoform-selective inhibitor with oral bioavailability. JBI-589 reduces CXCR2 expression and blocks neutrophil chemotaxis. JBI-589 reduces primary tumor and metastases, and enhances the anti-tumor effect of checkpoint inhibitors. JBI-589 can be used in cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2308504-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-153450. | |
| JBIR-15 | JBIR-15 is an aspochracin derivative metabolized from Aspergillus sclerotiorum. It exhibits antifungal activity against C. albicans. Synonyms: Antibiotic JBIR-15; (2E,4E,6E)-N-[(3S,6S,9S)-3,7-dimethyl-6-(1-methylethyl)-2,5,8-trioxo-1,4,7-triazacyclododec-9-yl]-2,4,6-octatrienamide. Grade: ≥95%. CAS No. 1198588-57-6. Molecular formula: C22H34N4O4. Mole weight: 418.53. | |
| J(Boc) Acetic acid | A nucleobase for PNA synthesis. Synonyms: N2-(tert-butoxycarbonyl)isocytosin-5-ylacetic acid. Grade: 98%. CAS No. 221362-48-7. Molecular formula: C11H15N3O5. Mole weight: 269.26. | |
| JBSNF-000028 free base | JBSNF-00002 free base is an orally active small molecule inhibitor of the tricyclic nicotinamide N-methyltransferase (NNMT) with IC50 values for human, mouse and monkey sources of NNMT of 33, 210 and 190 nM respectively. JBSNF-00002 free base can reduce endogenous MNA levels in U2OS osteosarcoma cells, with its EC50 being 2.5 μM. JBSNF-00002 free base exhibits significant anti-obesity and anti-diabetic activities in the diet-induced obesity (DIO) model. JBSNF-00002 free base can be used for the study of metabolic diseases such as obesity, type 2 diabetes and non-alcoholic fatty liver disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3026599-90-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-151500. | |
| JBSNF-000088 | JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 μM, 2.8 μM, and 5.0?μM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Methoxynicotinamide. CAS No. 7150-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-112584. | |
| JC-1 | The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590nm) in healthy cells. After cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio. Group: Biochemicals. Alternative Names: 5, 5', 6, 6'-Tetrachloro-1, 1', 3, 3'-tetraethyl benzimidazolyl carbocyanine iodide. Grades: Highly Purified. CAS No. 3520-43-2, 47729-63-5. Pack Sizes: 1mg, 5x1mg. Molecular Formula: C25H27Cl4IN4. US Biological Life Sciences. | Worldwide |
| JC-1 | JC-1 (CBIC2) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm); When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBIC2. CAS No. 3520-43-2. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15534. | |
| JCN037 | JCN037 (JGK037) is non-covalent and BBB-penetrant EGFR tyrosine kinase inhibitor, with IC50 values of 2.49 nM, 3.95 nM, 4.48 nM for EGFR, p-wtEGFR and pEGFRv?, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JGK037. CAS No. 2305154-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136430. | |
| JCpep7 | JCpep7 is cationic antimicrobial peptide isolated from Jatropha curcas. It has activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Lys-Val-Phe-Leu-Gly-Leu-Lys. Grade: 95.6%. Molecular formula: C40H69N9O8. Mole weight: 804.04. | |
| JD-5037 | JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1392116-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18697. | |
| JDTic dihydrochloride | JDTic (dihydrochloride) is a potent antagonist of kappa-opioid receptors (KOR), blocking the κ-agonist U50, 488-induced antinociception. Uses: Scientific research. Category: Signaling pathways. CAS No. 785835-79-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10487. | |
| Jedi2 | Jedi2 is a Piezo1 activator, but not a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770??μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 651005-90-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131018. | |
| Jellein-1 | Jellein-1 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Pro-Phe-Lys-Ile-Ser-Ile-His-Leu-NH2. Grade: 98.3%. Molecular formula: C47H76N12O9. Mole weight: 952.2. | |
| Jellein-2 | Jellein-2 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Thr-Pro-Phe-Lys-Ile-Ser-Ile-His-Leu. Grade: 97.2%. Molecular formula: C51H83N13O11. Mole weight: 1053.3. | |
| Jellein-3 | Jellein-3 is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Glu-Pro-Phe-Lys-Ile-Ser-Ile-His-Leu. Grade: 97.1%. Molecular formula: C52H83N13O12. Mole weight: 1081.3. | |
| Jelleine-I | Jelleine-I is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Pro-Phe-Lys-Leu-Ser-Leu-His-Leu-NH2. Grade: 96.8%. Molecular formula: C47H76N12O9. Mole weight: 952.2. | |
| Jelleine-II | Jelleine-II is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Thr-Pro-Phe-Lys-Leu-Ser-Leu-His-Leu. Grade: 96.4%. Molecular formula: C51H83N13O11. Mole weight: 1053.3. | |
| Jelleine-III | Jelleine-III is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Glu-Pro-Phe-Lys-Leu-Ser-Leu-His-Leu. Grade: 98.0%. Molecular formula: C52H83N13O12. Mole weight: 1081.3. | |
| Jenamidine A | It inhibited K-562 proliferation of chronic myeloid leukemia cells with Gl50 of 1.9 μg/mL. Molecular formula: C13H18N2O3. Mole weight: 250.29. | |
| Jenner's Stain | Jenner's Stain. Uses: For analytical and research use. Alternative Names: Eosinmethylene-blue; Methyl Eosin; C.I.45385. CAS No. 62851-42-7. Molecular formula: C21H9Br4KO5. Mole weight: 700.0. IUPAC Name: potassium;2,4,5,7-tetrabromo-9-(2-methoxycarbonylphenyl)-6-oxoxanthen-3-olate. Catalog: APB62851427. |  |
| Jenner's Stain | 25g Pack Size. Group: Stains & Indicators. Formula: N/A. CAS No. 62851-42-7. Prepack ID 83126591-25g. See USA prepack pricing. |  |
| Jenner Stain Certified | Jenner Stain Certified. Group: Biochemicals. Alternative Names: Eosin-Methylene blue. Grades: Highly Purified. CAS No. 62851-42-7. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| Jenner Stain, Certified ≥84% (HPLC) | Jenner Stain, Certified ≥84% (HPLC). Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 5g, 25g. US Biological Life Sciences. | Worldwide |
| Jervine | Jervine. Group: Biochemicals. Grades: Purified. CAS No. 469-59-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Jervine ((3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one) | Has antibacterial properties. Jervine demonstrates teratogenic properties. It is the starting material for C-nor-D-homosteroids. Jervine induces holoprosencephaly and blocks endogenous Sonic hedgehog signaling. Group: Biochemicals. Alternative Names: (3ß,23ß)-17,23-Epoxy-3-hydroxyveratraman-11-one. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Jesaconitine | Jesaconitine. Group: Biochemicals. Grades: Highly Purified. CAS No. 16298-90-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C35H49NO12. US Biological Life Sciences. | Worldwide |
| JET-209 | JET-209 is a potent CBP/p300 PROTAC degrader, with DC50 values of 0.05 nM and 0.2 nM for CBP and p300. JET-209 demonstrates remarkable anti-tumor activity against various acute leukemia cell lines and effectively inhibits tumor growth in xenograft tumor models. JET-209 can be used for the study of acute leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033714-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-154984. | |
| JG-2016 | JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1) with an IC50 of 14.8 μM. JG-2016 can inhibit the growth of multiple tumor cells and has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2887480-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154944. | |
| JG-231 | JG-231 is an allosteric inhibitor of heat shock protein 70 (Hsp70). JG - 231 inhibits the binding of Hsp70 and BAG family proteins, including inhibition of Hsp70 and BAG1 with a Ki of 0.11 μM. JG-231 inhibits proliferation of tumor cells and induces apoptosis. JG-231 has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627126-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124611. | |
| JG26 | JG26 is an ADAM inhibitor with IC50 values of 12 nM, 1.9 nM, and 150 nM for ADAM8, ADAM17, and ADAM10, respectively. JG26 inhibits MMP-12 with an IC50 value of 9.4 nM. JG26 inhibits AngII (HY-13948)-induced EGFR transactivation and ERK activation. JG26 increases the expression of ACE2, inhibits the cleavage of CD23, reduces the infection of SARS-CoV-2. JG26 inhibits colorectal cancer metastasis. JG26 can be used for research on Hodgkin lymphoma and vascular diseases[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1464910-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120852. | |
| JG-98 | JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1456551-16-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117282. | |
| JH295 | JH295 is a potent, irreversible and selective NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 770 nM. JH295 inhibits cellular Nek2 via alkylation of Cys22. JH295 is inactive against the mitotic kinases, Cdk1, Aurora B or Plk1, and does not perturb bipolar spindle assembly or the spindle assembly checkpoint[1]. JH295 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1311143-71-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116423. | |
| JH-II-127 | JH-II-127 is an orally active, highly potent, selective and brain-permeable LRRK2 inhibitor, with IC50s of 6, 2 and 48 nM for wild-type LRRK2 and LRRK2-G2019S and mutant LRRK2-A2016T. JH-II-127 inhibits Ser935 phosphorylation in all tissues of mice, including the brain. JH-II-127 can be used in the study of parkinson's syndrome[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1700693-08-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16936. | |
| JH-LPH-107 | JH-LPH-107 is a LpxH inhibitor. JH-LPH-107 exhibits a low rate of spontaneous resistance and a high safety window in vitro.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053068-92-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168649. | |
| JH-LPH-28 | JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414592-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130837. | |
| JH-LPH-33 | JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414590-04-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130838. | |
| JH-RE-06 | JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1361227-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126214. | |
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