A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC50s of 0.028 and 2.75 μM for OX2R and OX1R, respectively. YNT-185 ameliorates narcolepsy-cataplexy symptoms in mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1804978-81-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136181A.
YO-01027 (Dibenzazepine;DBZ) is a potent γ-secretase inhibitor with IC50 values of 2.92 and 2.64 nM for Notch and APPL cleavage, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Dibenzazepine; DBZ. CAS No. 209984-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13526.
Yoda1
Yoda1 acts as an agonist for both human and mouse Piezo1(EC50 of 17.1 and 26.6 μM for mouse and human). Yoda1 activates purified Piezo1 channels in the absence of other cellular components. Group: Inhibitors. CAS No. 448947-81-7. Pack Sizes: 5mg. Product ID: S6678. Formula: C13H8Cl2N4S2. Smiles: C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl. Storage Conditions: 3 years -20°C powder.
United States; Europe
Yoda 1
Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 448947-81-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-18723.
Yohimban-16-carboxylic acid,1-[2-(diethylamino)ethyl]-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-,methyl ester,(3beta,16beta,17alpha,18beta,20alpha)-,[r-(r*,r*)]-2,3-dihydroxybutanedionate. Alternative Names: Bietaserpine bitartrate;Tensibar. CAS No. 1111-44-0. Product ID: ACM1111440. Molecular formula: C39H53N3O9.C4H6O6. Alfa Chemistry - ISO 9001:32057 Certified.
Yohimbe bark
Yohimbe bark. Group: Biochemicals. Alternative Names: Yohimbine. Grades: Highly Purified. CAS No. 146-48-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Yohimbe Extract
Yohimbe Extract. Applications: Used for men health care products, dietary supplements, treat sexual impotence and sexual dysfunction. Group: Others. Synonyms: Yohimbe Extract; 65-19-0; Corynante Yohimbe. CAS No. 65-19-0. Purity: 8% Yohimbine by HPLC. Appearance: Red brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Bark. Species: Corynante Yohimbe. Yohimbe Extract; 65-19-0; Corynante Yohimbe; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-077.
Yohimbic acid
Yohimbic acid is a derivative of Yohimbine Hydrochloride (HY-N0127). Yohimbic acid exhibits vasodilatory and anticancer activities. Yohimbic acid can be used for the research of cancer, inflammation and cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 522-87-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121936.
Yohimbic acid
Yohimbic acid. Alternative Names: 17α-Hydroxyyohimban-16α-carboxylic acid. CAS No. 522-87-2. Purity: >99.0%. Product ID: FFC-AR-522872. Molecular formula: C20H24N2O3. Mole weight: 340.42. IUPAC Name: (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Yohimbine-[13C,d3]
One of the isotopic labelled form of Yohimbine, an indole alkaloid compound, has been found to exhibit α2-adrenergic blocking effect and could be used in the treatment of neurological disorders. Synonyms: Yohimbine-(methyl-13C,d3 ester). Grade: ≥98% atom (CP); ≥99% atom. CAS No. 1261254-59-4. Molecular formula: C20[13C]H23D3N2O3. Mole weight: 358.45.
Yohimbine EP Impurity A. Uses: For analytical and research use. CAS No. 549-84-8. Molecular formula: C21H26N2O3. Mole weight: 354.5. Catalog: APB549848.
Yohimbine EP Impurity B
Yohimbine EP Impurity B. Uses: For analytical and research use. Alternative Names: α-yohimbine (EP) ; Rauwolscine. CAS No. 131-03-3. Molecular formula: C21H26N2O3. Mole weight: 354.5. Catalog: APB131033.
Yohimbine EP Impurity C
Yohimbine EP Impurity C. Uses: For analytical and research use. Alternative Names: Corynantheine (EP). CAS No. 483-10-3. Molecular formula: C21H26N2O3. Mole weight: 354.5. Catalog: APB483103.
Yohimbine EP Impurity D
Yohimbine EP Impurity D. Uses: For analytical and research use. CAS No. 84-37-7. Molecular formula: C21H26N2O3. Mole weight: 354.5. Catalog: APB84377.
Yohimbine HCl
Yohimbine HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 65-19-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C21H26N2O3·HCl. US Biological Life Sciences.
Yohimbine, an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa, has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac. Uses: Antidepressant. Synonyms: CORYNINE HYDROCHLORIDE; APHRODINE HYDROCHLORIDE; APHROSOL HYDROCHLORIDE; 17-HYDROXYYOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE; 17A-HYDROXYYOHIMBAN-16A-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE; YOHIMBE HCL; YOHIMBINE HCL; YOHIMBINE HYDROCHLORIDE. Grade: >98%. CAS No. 65-19-0. Molecular formula: C21H26N2O3·HCl. Mole weight: 390.9.
Yohimbine Hydrochloride
Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 65-19-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Yohimbine Hydrochloride
Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis. Uses: Scientific research. Category: Induced disease models products. CAS No. 65-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N0127.
A potent antagonist for alpha-2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human alpha-2a, alpha-2B and alpha-2C receptors respectively). Often used as pharmacological stressor in animal studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 65-19-0. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
YOK-1304
YOK-1304 is a ligand of p62-ZZ domain. YOK-1304 can activate p62-dependent selective macroautophagy. YOK-1304 can be used for AUTOTAC design[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2409960-03-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161739.
Yokonolide A
It is produced by the strain of Streptomyces diastatochromogenes B59. It can inhibit the signal transduction of thaliphin. Synonyms: (1S,4E,6R,6'R,7S,8R,9R,10R,11S,12S,16E,18S,19S,21S,23R,25R)-6,7,9,11,19-Pentahydroxy-6'-[(2R)-2-hydroxybutyl]-18-[(2S)-3-hydroxy-2-methylpropyl]-6,8,12,25-tetramethyl-3-oxo-3',4',5',6'-tetrahydrospiro[2,22-dioxabicyclo[19.3.1]pentacosa-4,16-diene-23,2'-pyran]-10-yl 2,4,6-trideoxy-4-(dimethylamino)-alpha-L-lyxo-hexopyranoside. Molecular formula: C47H83NO14. Mole weight: 886.16.
YOP Protein Tyrosine Phosphatase from Yersinia enterocolitica, Recombinant
Protein tyrosine phosphatases are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification that can create novel recognition motifs for protein interactions and cellular localization, affect protein stability, and regulate enzyme activity. As a consequence, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC 3.1.3.48) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzym.rentiation, transformation, and synaptic strengthening. Recombinant, expressed in e. coli, > 50 kda unit/ml, buffered aqueous glycerol solution. Applications: Used to release phosphate groups specifically from phosphotyrosine residues in proteins. Group: Enzymes. Synonyms: YOP Protein Tyrosine Phosphatase; Protein tyrosine phosphatase; Tyrosine-specific protein phosphatases; PTPase. PTPase. Activity: > 50,000 unit/mL. Stability: -20°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Yersinia enterocolitica. YOP Protein Tyrosine Phosphatase; Protein tyrosine phosphatase; Tyrosine-specific protein phosphatases; PTPase. Cat No: NATE-0642.
YO-PRO-1
YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/530±30 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152068-09-2. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-D0918.
YoungBoard Conductive XLPE
YoungBoard is a semi-rigid, chemically cross-linked polyethylene block-type foam with a closed-cell foam structure. Characteristics include a fine, homogenous cell structure with superb insulation, cushioning, and water-repellent properties. Furthermore, YoungBoard has a smooth feel and printable surface.
Yparex
Yparex.
Y-PEG40K-Acetaldehyde
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-PEG-Acetaldehyde. Mole weight: average Mn 40000.
Y-PEG40K-Alkyne
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
Y-PEG40K-COOH
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-PEG-COOH. Mole weight: average Mn 40000.
Y-PEG40K-Fluorescein
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Mole weight: average Mn 40000. Purity: ≥95%.
Y-PEG40K-MAL
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-PEG-MAL. Mole weight: average Mn 40000.
Y-PEG40K-NH2
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-shape PEG Amine, Y-PEG-NH2. Mole weight: average Mn 40000.
Y-PEG40K-NHS
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-PEG-NHS. Mole weight: average Mn 40000.
Y-PEG40K-Propionaldehyde
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: Y-PEG-Propionaldehyde. Mole weight: average Mn 40000.
YQ456
YQ456 is a novel small molecule inhibitor of myoferlin that showed high binding affinity to myoferlin with a KD of 37 nM and excellent anti-invasion capability with an IC50 of 110 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2093946-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-143539.
YRGDS Fibronectin Fragment
YRGDS Fibronectin Fragment is an adhesion peptide, a fibronectin fragment which displays strong binding affinity to thrombin-stimulated platelets. Synonyms: H-Tyr-Arg-Gly-Asp-Ser-OH; YRGDS. Grade: 95%. CAS No. 134282-68-1. Molecular formula: C24H36N8O10. Mole weight: 596.59.
YS-035 hydrochloride
YS-035 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 89805-39-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
YS110
YS110 is a humanized anti-CD26 (DPP4) IgG1 monoclonal antibody. YS110 induces CD26 nuclear translocation through the caveolin pathway. YS110 inhibits the proliferation of tumor cell by delaying G2/M cell cycle transition. YS110 inhibits the infection of Middle East respiratory syndrome coronavirus (MERS CoV) by blocking the binding of MERS CoV S1 to CD26. YS110 can be used for researches on cancer or infection such as Malignant Mesothelioma and MERS[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1656248-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991551.
YS-822A
YS-822A is a polyene macrolide antibiotic isolated from the culture filtrate of a mutant strain H-8 of Streptoverticillium eurocidicum var. asterocidicus S-822. It has antifungal activity with MIC of 3.12-12.5μg/mL for yeast. Synonyms: YS 822A; Antibiotic YS 822A; 10,29-Dioxabicyclo(23.3.1)nonacosa-15,17,19,21-tetraene-26-carboxylic acid, 23-((3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy)-1,3,5,6,27-pentahydroxy-11-(1-methylethyl)-9-oxo-. CAS No. 130767-46-3. Molecular formula: C37H59NO14. Mole weight: 741.9.
Ysamber ® K
Ysamber ® K. CAS No. 154171-76-3. VIGON Item # 502547. Categories: Speciality Ingrdients Suppliers, Fragrances, amber spirolene, Perfumers.
America & Internationally
Y-Shaped-PEG-Acrylate
CD Bioparticles provides Y-Shaped-PEG-Acrylate with a PEG molecular weight of 2,000 Da for drug delivery. Group: Y-shaped pegs.
YSK 12C4
YSK 12C4 is an ionizable cationic lipid primarily used to enhance siRNA cellular delivery via multifunctional envelope-type nanodevices (MEND). YSK 12C4 promotes siRNA uptake and endosomal escape, effectively silencing genes in human immune cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1829511-70-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-160852.
YSZ Grinding Media
YSZ Grinding Media. Alternative Names: YSZ Grinding Media. Purity: 99.9%.
YTHDC1-IN-1
YTHDC1-IN-1 is a selective YTHDC1 inhibitor with a Kd of 49 nM and an IC50 of 0.35 μM. YTHDC1-IN-1 can inhibit the proliferation and induce apoptosis of acute myeloid leukemia cell lines. YTHDC1-IN-1 has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2995344-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158974.
YTHDF2 ligand-1
YTHDF2 ligand-1 (Compound 23) is a competitive, selective, and high-affinity YTHDF2 ligand with an IC50 of 11 μM and a Kd of 1.3 μM. YTHDF2 ligand-1 competes with m6A-RNA for binding to YTHDF2. YTHDF2 ligand-1 is applicable for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3093182-34-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-174982.
YTH-IN-1
YTH-IN-1 (compound N-7) is a pan-YTH domain inhibitor with the IC50 values of 39 μM, 34 μM, 35 μM, 48 μM and 30 μM for human YTHYTHDF1, YTHYTHDF2, YTHYTHDF3, YTHYTHDC1, and YTHYTHDC2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2189366-92-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168610.
YTK-105
YTK-105 is a p62/ZZ binding domain ligand and Autophagy enhancer. YTK-105 activates p62-dependent selective macroautophagy. YTK-105 serves as an autophagy-targeting ligand (ATL) for synthesizing AUTOTAC degraders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 774192-20-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W489121.
YTP-17
YTP-17 is an orally active YAP-TEAD protein-protein interaction inhibitor with an IC50 of 4 nM. YTP-17 shows anti-tumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2714433-21-1. Pack Sizes: 1 mg. Product ID: HY-150256.
Ytterbium 2,4-pentanedionate
Ytterbium 2,4-pentanedionate. Grades: 99.9% Extremely High (>=99%). CAS No. 14284-98-1. Pack Sizes: Gram Quantities: 2 gm, 10 gm. Order Number: 3814.
www.prochemonline.com
Ytterbium Acetate
Ytterbium Acetate. Grades: 99.9% Extremely High (>=99%). CAS No. 15280-58-7. Pack Sizes: Gram Quantities: 10 gm, 50 gm. Order Number: 3787.
www.prochemonline.com
Ytterbium Acetate
YTTERBIUM ACETATE, TETRAHYDRATE, 99.9% pure, -6 mesh, Formula: Yb(OOCCH3)3.4H2O. CAS No. 15280-58-7. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today!