A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Yeast Nitrogen Base Medium without Amino Acids. Uses: For analytical and research use. Alternative Names: YNB Medium without Amino Acids. Catalog: APB12453.
yeast ribonuclease
Similar enzyme: RNase U4. Group: Enzymes. Enzyme Commission Number: EC 3.1.14.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3541; yeast ribonuclease; EC 3.1.14.1. Cat No: EXWM-3541.
Yeast S
A dried Aspergillus oryzae fermentation extract that is an ideal nutrient support system for yeast during the fermentation process. It contains protein, free-form amino acids, minerals, enzymes, vitamins, fiber and other nutrients. Group: Enzymes. Synonyms: Yeast S; Yeast; BRE-1622. Yeast S. Appearance: powder or liquid. Yeast S; Yeast; BRE-1622. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form) or subject to client requirement. Cat No: BRE-1622.
Yeasts. Riched selenium
Yeasts. Riched selenium. Product ID: CDF4-0217. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0217; Yeasts. Riched selenium; Nutrient supplements. Applications: Used as selenium enhancer in dairy products, rice products, biscuits and beverages.
Yellow Dextrin Nanopowder
Yellow Dextrin Nanopowder. CAS No. 9004-53-9. Purity: 99.9%.
Yellow iron oxide
Yellow iron oxide. CAS No. 1309-33-7. Product ID: ACM1309337. Molecular formula: FeH3O3. Mole weight: 106.86702. Alfa Chemistry - ISO 9001:32057 Certified.
Yellow Iron Oxide USP
Yellow Iron Oxide USP. CAS No. 51274-00-1.
YF-0200R-A
YF-0200R-A is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.5 x 10(-4) M. Synonyms: YF 0200R-A; YF 0200R A; 8,12-Dihydroxy-2,4-dodecadienoic acid. CAS No. 156368-99-9. Molecular formula: C12H20O4. Mole weight: 228.28.
YF-0200R-B
YF-0200R-B is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.2 x 10(-4) M. Synonyms: YF 0200R-B; YF 0200R B; 8,10,12-trihydroxydodeca-2,4-dienoic acid. CAS No. 156369-00-5. Molecular formula: C12H20O5. Mole weight: 244.28.
YF-044P-D
YF-044P-D is a Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. SF-044P. It inhibits Candida albicans aspartyl protease with IC50 of 6.4 X 10(-7) mol/L. Synonyms: YF 044P-D; YF-044-P-D. CAS No. 158335-52-5. Molecular formula: C43H57N5O9. Mole weight: 787.9.
YF-2
YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1311423-89-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16531.
YFGAP
YFGAP is an antibacterial peptide isolated from Yellowfin tuna (Thunnus albacares). It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: YFGAP-OH; Val-Lys-Val-Gly-Ile-Asn-Gly-Phe-Gly-Arg-Ile-Gly-Arg-Leu-Val-Thr-Arg-Ala-Ala-Phe-His-Gly-Lys-Lys-Val-Glu-Val-Val-Ala-Ile-Asn-Asp. Molecular formula: C154H258N48O40. Mole weight: 3422.04.
YG1702
YG1702 is a potent ALDH18A1-specific inhibitor. YG1702 attenuates the growth of MYCN-amplified NB and down-regulates MYCN. YG1702 physically interacts with ALDH18A1 with a high affinity and might potentially affect its enzymatic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 724737-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156443.
Yhhu-3792
Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2097826-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120782.
YHO-13177
YHO-13177, a acrylonitrile derivative, is an orally active, potent and specific inhibitor of breast cancer resistance protein (BCRP) and ABCG2 with an IC50 value of 10 nM. YHO-13177 potentiates the cytotoxicity of SN-38 in HCT116 and A549 cells that express BCRP. YHO-13177 combined with Irinotecan (HY-16562) significantly suppresses the tumor growth in an HCT116/BCRP xenograft model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 912287-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12757.
YHO-13351
YHO-13351 is an orally active ABCG2 inhibitor. YHO-13351 modulates the function of ABCG2, blocks BCRP-mediated compound efflux, downregulates the expression of breast cancer resistance protein at the post-transcriptional level, and reverses ABCG2-associated tolerance. YHO-13351 restores the toxicity of SN-38 to SN-38-resistant cancer cells and sensitizes cancer cells to Irinotecan. YHO-13351 is a water-soluble prodrug that is rapidly converted to YHO-13177 (HY-12757) in mice. YHO-13351 prolongs the median survival time of mice bearing cancer cell xenografts when combined with IMMU-132. YHO-13351 extends the survival time of tumor-bearing mice and inhibits the growth of xenograft tumors when combined with Irinotecan. YHO-13351 can be used for the research of breast cancer, gastric cancer, BCRP-mediated drug-resistant cancers, and cervical cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346753-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-12758.
YHO-13351 free base
YHO-13351 free base is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. Uses: Scientific research. Category: Signaling pathways. CAS No. 912288-64-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12758A.
YIGSR
YIGSR (Laminin Fragment 929-933) is a polypeptide that inhibits tumor growth and metastasis of leukemia cells. YIGSR specifically binds to the 67kDa laminin receptor and regulates the expression of eNOS in endothelial cells. YIGSR can be used in leukemia-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Laminin Fragment 929-933. CAS No. 110590-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0132.
YIL781
YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL781 inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 875258-85-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-13964.
YIL781 hydrochloride
YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL781 hydrochloride inhibits the calcium response induced by ghrelin with pIC50 values of 7.90 and 8.27, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1640226-17-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13964A.
YIL 781, Hydrochloride Salt
Ghrelin receptor antagonist (GHS-R1a) (Ki = 17nM). Displays no significant affinity for the motilin receptor (Ki = 6uM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo. Group: Biochemicals. Alternative Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 875258-85-8. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?.HCl, Molecular Weight: 445.96. US Biological Life Sciences.
Worldwide
YJ1206
YJ1206 is an orally active selective CDK12/CDK13 PROTAC degrader. YJ1206 induces DNA damage and genomic instability, activates the AKT pathway, and triggers apoptosis. YJ1206 reduces tumor cell viability, inhibits tumor growth, and attenuates tumor cell dissemination. YJ1206 is applicable to research related to prostate cancer and high-grade serous tubo-ovarian cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053716-98-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-168555.
YK11
YK11 is a partial agonist of androgen receptor, with osteogenic activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1370003-76-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107480.
YK-2-69
YK-2-69 is a highly selective DYRK2 inhibitor with an IC50 value of 9?nM. YK-2-69 specifically interacts with Lys-231 and Lys-234 of DYRK2 and can be utilized in researches related to prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2619846-89-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153949.
YK-4-279
YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1037184-44-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14507.
YKL-05-099
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1936529-65-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-101147.
YKL-06-061
YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2172617-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120056.
YKL-1-116
YKL-1-116 is a selective and covalent inhibitor of Cdk7. YKL-1-116 does not target Cdk9, Cdk12, or Cdk13. YKL-1-116 is more potent than THZ1 (HY-80013) toward both Cdk7WT and Cdk7as, although Cdk7as is relatively resistant to this compound as well[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1957202-71-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116871.
YKL-5-124
YKL-5-124 is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1957203-01-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101257.
YKL-5-124 TFA
YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 TFA is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 TFA induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2748220-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-101257B.
YL-365
YL-365 is a potent and selective GPR34 antagonist with an IC50 of 17 nM. YL-365 binds to a portion of the orthosteric binding pocket of GPR34 and induces allosteric changes that stabilize the receptor in an inactive conformation. YL-365 down-regulates expression of the proinflammatory gene iNOS in M1 microglia and suppresses proinflammatory responses. YL-365 reduces mechanical allodynia in a dose-dependent manner in a mouse model of neuropathic pain. YL-365 can be used for the research of neuropathic pain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077715-58-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156815.
YL-5092
YL-5092 is a selective YT521-B homology (YTH) domain-containing protein 1 (YTHDC1) inhibitor with an IC50 of 7.4 nM and a KD of 29.6 nM. YL-5092 can suppress cancer cell proliferation and induce cell G0/G1 phase arrest and apoptosis. YL-5092 can be used for the research of cancer, such as acute myeloid leukemia (AML)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3056857-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164607.
YL-704A1
YL-704A1 is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Synonyms: Yl 704A1; Yl 704 A1. CAS No. 40615-47-2. Molecular formula: C43H71NO15. Mole weight: 842.
YL-939
YL-939 is a potent ferroptosis inhibitor. YL-939 inhibits ferroptosis by targeting the PHB2/ferritin/iron axis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3023925-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152093.
Ylangenol
Ylangenol is extracted from Laggera pterodonta. Synonyms: (8-Isopropyl-1-methyltricyclo[4.4.0.02,7]dec-3-en-3-yl)methanol. Grade: 95%. CAS No. 41610-69-9. Molecular formula: C15H24O. Mole weight: 220.35.
Ylang-ylang oil
Ylang-ylang oil. CAS No. 8006-81-3. Purity: 0.98. Product ID: CI-EO-0064. Alfa Chemistry - ISO 9001:32057 Certified.
Ylang Ylang Oil
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: N/A. CAS No. 8006-81-3. Prepack ID 89992786-100g. See USA prepack pricing.
YM022
YM022 is a highly potent, selective and orally active gastrin/cholecystokinin (CCK)-B receptor (CCK-BR) antagonist. YM022 shows the Ki values of 68 pM and 63 nM for CCK-B and CCK-A receptor, respectively[1]. YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 145084-28-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103355.
YM 022
YM 022. Group: Biochemicals. Grades: Highly Purified. CAS No. 145084-28-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
YM-1
YM-1 is a stable MKT-077 (HY-15096) analog and an orally active Hsp70 inhibitor. YM-1 induces cell death of HeLa cells and up-regulates the level of p53 and p21 proteins[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 409086-68-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18399.
YM155
YM155. Group: Biochemicals. Alternative Names: 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium Bromide; Sepantronium bromide; YM 155. Grades: Highly Purified. CAS No. 781661-94-7. Pack Sizes: 10mg. Molecular Formula: C20H19BrN4O3, Molecular Weight: 443.29. US Biological Life Sciences.
Worldwide
YM-170320
YM-170320 is a lipopeptide antibiotic produced by an unidentified fungal strain YL-03706F. It was shown to induce morphological change of colonies in a mutant of Candida tropicalis pK233. It is a novel ergosterol biosynthesis inhibitor. Synonyms: 5-Amino-4-hydroxy-5-oxo-2-[[3-[[2-[(2,6,10,14-tetramethyl-3-hydroxy-1,7-dioxo-8,10-icosadiene-1-yl)amino]propenoyl]amino]-2-methylpropanoyl]amino]pentanoic acid methyl ester. Molecular formula: C37H62N4O9. Mole weight: 706.91.
YM-181741
YM-181741 is a novel benz[a]anthraquinone antibiotic isolated from the culture broth of actinomycete strain Q57219. It showed selective anti-Helicobacterpylori activity with a MIC value of 0.2 microg/ml. Molecular formula: C19H14O5. Mole weight: 322.3.
YM-201636
YM-201636 is a potent and selective PIKfyve inhibitor with an IC50 of 33 nM. YM-201636 also inhibits p110α with an IC50 of 3.3 μM. YM-201636 inhibits retroviral replication. Uses: Scientific research. Category: Signaling pathways. CAS No. 371942-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13228.
YM 202074
High affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. Binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. Inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 299900-84-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
YM-202204
YM-202204 is an antifungal antibiotic isolated from the culture broth of marine fungus Phoma sp. Q60596. It exhibited potent antifungal activities against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and also inhibited glycosyl-phosphatidyl-inositol (GPI)-anchoring in yeast cells. Synonyms: 6'-(2,8-Dihydroxy-1,5,7,9,13,15,17-heptamethyl-nonadeca-3,5,11,13-tetraenyl)-3,4,4'-trihydroxy-6-hydroxymethyl-3,4,5,6-tetrahydro-2H-[2,3']bipyranyl-2'-one. Molecular formula: C37H58O9. Mole weight: 646.8.
YM-24074
YM-24074 is a type I collagenase inhibitor isolated from Streptomyces sp. YL-01869P. Synonyms: YM 24074. Molecular formula: C21H38N4O5. Mole weight: 426.6.
YM 244769
YM 244769. Group: Biochemicals. Grades: Highly Purified. CAS No. 837424-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
YM-254890
YM-254890 is a selective Gαq/11 protein inhibitor isolated from Chromobacterium sp. QS3666. YM-254890 (1, 3, and 10 μg/kg) reduces platelet thrombus formation in a cynomolgus monkey model of femoral artery thrombosis. CAS No. 568580-02-9. Molecular formula: C46H69N7O15. Mole weight: 960.1.
YM-254890
YM-254890 is a selective Gαq/11 protein inhibitor isolated from Chromobacterium sp. YM-254890 shows no inhibition of other G protein subtypes. YM-254890 inhibits platelet aggregation induced by ADP by blocking the P2Y1 signal transduction pathway, with an IC50 value below 0.6 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 568580-02-9. Pack Sizes: 250 μg; 500 μg; 1 mg. Product ID: HY-111557.
YM-266183
YM-266183 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Synonyms: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41,44-dihydroxy-17'-oxomicrococcin P. Molecular formula: C48H47N13O10S6. Mole weight: 1158.35.
YM-266184
YM-266184 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Synonyms: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41-hydroxy-44-methoxy-17'-oxomicrococcin P. Molecular formula: C49H49N13O10S6. Mole weight: 1172.37.
YM 26734
YM 26734. Group: Biochemicals. Grades: Purified. CAS No. 144337-18-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
YM-30059
YM-30059 is a quinolone antibiotic produced by Arthrobacter sp. YL-02729S. It shows anti-gram-positive bacterial activity and cytotoxicity. It also inhibits li poxygenase. Synonyms: YM 30059. Molecular formula: C19H25NO2. Mole weight: 299.4.
YM-32890 A
YM-32890 A is a macrolide antibiotic isolated from the fermentation broth of cytophaga sp. YL-02905S. It inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast. Synonyms: YM-32890A; YM-32890-A. Molecular formula: C33H48O6. Mole weight: 540.7.
YM-32890 B
YM-32890 B is a macrolide antibiotic isolated from the fermentation broth of cytophaga sp. YL-02905S. Synonyms: YM-32890B; YM-32890-B. Molecular formula: C33H48O6. Mole weight: 540.7.
YM-341619
YM-341619 (AS1617612) is a potent and orally active STAT6 inhibitor with an IC50 of 0.70 nM. YM-341619 inhibits Th2 differentiation in mouse spleen T cells induced by IL-4 (IC50=0.28 nM) without affecting Th1 cell differentiation[1]. YM-341619 is a promising compound for the the research of allergic diseases, such as allergic asthma[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AS1617612. CAS No. 643082-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134771.
YM-47141
YM-47141 is a cyclic-depsipeptide produced by Flexibacter sp. Q17897. It acts as an elastase inhibitor with IC50 of 1.5 X 10(-7) mol/L. Synonyms: YM 47141; N-(phenylacetyl)-L-phenylalanyl-N-[(3R,6S,9S,14S,17S,18R)-6-(2-amino-2-oxoethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,5,8,11,12,13,16-heptaoxo-1-oxa-4,7,10,15-tetraazacyclooctadecan-17-yl]-L-threoninamide. Molecular formula: C46H62N8O13. Mole weight: 935.
YM-47142
YM-47142 is a cyclic-depsipeptide produced by Flexibacter sp. Q17897. It acts as an elastase inhibitor with IC50 of 3.0 X 10(-7) mol/L. Synonyms: YM 47142; N-(3-methylbutanoyl)-L-phenylalanyl-N-[(3R,6S,9S,14S,17S,18R)-6-(2-amino-2-oxoethyl)-3,18-dimethyl-9,14-bis(2-methylpropyl)-2,5,8,11,12,13,16-heptaoxo-1-oxa-4,7,10,15-tetraazacyclooctadecan-17-yl]-L-threoninamide. Molecular formula: C43H64N8O13. Mole weight: 901.
YM-47515
YM-47515 is an isonitrile antibiotic isolated from Micromonospora echinospora subsp. Echinospora. It is effective against gram-positive bacteria including MRSA. Synonyms: YM 47515. Molecular formula: C17H29NO4. Mole weight: 311.4.
YM-47522
YM-47522 is an antifungal antibiotic isolated from the culture broth of Bacillus sp. YL-03709B. It exhibited potent in vitro antifungal activity especially against Rhodotorula acuta and Pichia angusta (MIC = 0.05 and 0.75 mM/ml, respectively). It also showed moderate or weak antifungal activity against Candida albicans and Cryptococcus neoformans (MIC = 25 and 6.25 mM/ml, respectively). Synonyms: YM 47522. Molecular formula: C24H33NO4. Mole weight: 399.5.
YM-53601
YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo[1]. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent[2]. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 182959-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100313A.
YM 58483
YM 58483. Group: Biochemicals. Grades: Highly Purified. CAS No. 223499-30-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
YM-58483
YM-58483 (BTP2) is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. YM-584832 is a blocker of store-operated Ca2+ entry (SOCE)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BTP2. CAS No. 223499-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100831.
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 138046-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107396.
YM976
YM976 is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.2 nM. YM976 shows the dissociation of anti-inflammatory activities from emetic effects and inhibits the antigen-induced airway responses[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191219-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-108617.
YM 976
Orally active PDE4 inhibitor (IC50 = 2.2 nM). Low emetogenic activity, suggested to be due to poor brain penetration. Group: Biochemicals. Grades: Highly Purified. CAS No. 191219-80-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Y-(mPEG10K)2-(PEG20k-NH2)
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Mole weight: average Mn 40000.
YN-0165J-A
YN-0165J-A is an enteromycin group antibiotic produced by Streptomyces strain YN-0165J. It is effective against Gram-positive and -negative bacteria, but is inactive to Enterobacter cloacae and Pseudomonas aeruginosa. CAS No. 102692-05-7. Molecular formula: C7H13N3O4. Mole weight: 203.2.