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| Product | Description | |
|---|---|---|
| ALX 40-4C acetate | ALX 40-4C acetate is a small peptide inhibitor of the chemokine receptor CXCR4. It inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1. Molecular formula: C58H117N37O12. Mole weight: 1524.79. |  |
| ALX 40-4C Trifluoroacetate | ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, which inhibits the binding of SDF-1 to CXCR4 and inhibits the replication of X4 strain HIV-1. It is also an APJ receptor antagonist. Synonyms: Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2.TFA; N-acetyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide trifluoroacetic acid; ALX 40-4C TFA. Grade: >98%. Molecular formula: C56H113N37O10.C2HF3O2. Mole weight: 1578.76. | |
| ALX 5407 hydrochloride | ALX 5407 hydrochloride. Group: Biochemicals. Alternative Names: N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grades: Highly Purified. CAS No. 200006-08-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C24H25ClFNO3. US Biological Life Sciences. |  Worldwide |
| ALX 5407 hydrochloride | The hydrochloride salt form of ALX 5407, which has been found to be an inhibitor of the glycine transporter GlyT1 and could probably be useful in some neuropsychiatric disorders. Synonyms: ALX 5407 hydrochloride; ALX-5407 hydrochloride; ALX5407 hydrochloride; N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grade: ≥98% by HPLC. CAS No. 200006-08-2. Molecular formula: C24H24FNO3.HCl. Mole weight: 429.92. | |
| Alyteserin-1a | Alyteserin-1a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >96%. CAS No. 1159767-77-7. Molecular formula: C104H176N30O27. Mole weight: 2278.74. | |
| Alyteserin-1b | Alyteserin-1b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: ≥97%. CAS No. 1159767-78-8. Molecular formula: C105H178N30O27. Mole weight: 2292.76. | |
| Alyteserin-1c | Alyteserin-1c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-negative bacterium such as E. coli (MIC=25 μM). Synonyms: Gly-Leu-Lys-Glu-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Ser-NH2. Grade: 98%. CAS No. 1159767-79-9. Molecular formula: C104H177N29O27. Mole weight: 2265.74. | |
| Alyteserin-1d | Alyteserin-1d is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Gly-Leu-Lys-Asp-Ile-Phe-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Asn-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >98%. CAS No. 1159767-80-2. Molecular formula: C106H179N31O28. Mole weight: 2335.79. | |
| Alyteserin-1Ma | Alyteserin-1Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=214 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=214 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Asp-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Ala-Ala-His-Val-Ala-Asn-NH2. Grade: >98%. Molecular formula: C106H178N30O29. Mole weight: 2336.77. | |
| Alyteserin-1Mb | Alyteserin-1Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=217 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=434 μM). Synonyms: Gly-Phe-Lys-Glu-Val-Leu-Lys-Ala-Gly-Leu-Gly-Ser-Leu-Val-Lys-Gly-Ile-Pro-Ala-His-Val-Ala-Asn-NH2. Grade: ≥97%. Molecular formula: C106H178N30O27. Mole weight: 2304.77. | |
| Alyteserin-2a | Alyteserin-2a is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity against Gram-positive bacterium such as Staphylococcus aureus (MIC=50 μM). Synonyms: Ile-Leu-Gly-Lys-Leu-Leu-Ser-Thr-Ala-Ala-Gly-Leu-Leu-Ser-Asn-Leu-NH2. Grade: ≥96%. CAS No. 1159767-81-3. Molecular formula: C72H131N19O20. Mole weight: 1582.95. | |
| Alyteserin-2b | Alyteserin-2b is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Asn-Lys-Leu-NH2. Grade: >98%. CAS No. 1159767-82-4. Molecular formula: C81H146N20O20. Mole weight: 1720.18. | |
| Alyteserin-2c | Alyteserin-2c is an antimicrobial peptide produced by Alytes obstetricans (European midwife toad). It has antibacterial activity. Synonyms: Ile-Leu-Gly-Ala-Ile-Leu-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-Ser-Lys-Leu-NH2. Grade: >98%. CAS No. 1159767-83-5. Molecular formula: C80H145N19O20. Mole weight: 1693.15. | |
| Alyteserin-2Ma | Alyteserin-2Ma is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-negative bacterium: Escherichia coli NCTC 10418 (MIC=38.4 μM) and Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=9.5 μM). It only inhibits C. albicans at very high concentration of 150 uM. Synonyms: Phe-Ile-Gly-Lys-Leu-Ile-Ser-Ala-Ala-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grade: ≥97%. Molecular formula: C76H128N20O19. Mole weight: 1625.98. | |
| Alyteserin-2Mb | Alyteserin-2Mb is an antimicrobial peptide produced by Alytes maurus (Midwife toad). It has antibacterial and antifungal activity. It is active against Gram-positive bacterium: Staphylococcus aureus NCTC 10788 (MIC=19.3 μM). It only inhibits C. albicans at very high concentration of 310 uM. Synonyms: Ile-Leu-Gly-Ala-Ile-Ile-Pro-Leu-Val-Ser-Gly-Leu-Leu-Ser-His-Leu-NH2. Grade: ≥96%. Molecular formula: C77H135N19O18. Mole weight: 1615.04. | |
| Alytesin | Alytesin. Group: Biochemicals. Grades: Purified. CAS No. 31078-12-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Alytesin | Alytesin is an amphibian bombesin-like peptide originally isolated from the skin of the European amphibian, alytes obstetricans. It has biological activity very similar to bombesin. It could cause rat uterine contraction, intestinal contraction, gastric acid secretion and hypertension in vivo in the dog. It also adjusts thermoregulation following central administration in vivo. Synonyms: Alytesin; 31078-12-3; CID 16131139; XGRLGTQWAVGHLM; Alytesin (trifluoroacetate salt); BDBM85497; DTXSID40185027; Pgly-arg-leu-gly-thr-gln-trp-ala-val-gly-his-leu-met-NH2; AKOS024456835; AKOS040764257; CAS_31078-12-3; HY-103276; CS-0026803; J-018236. CAS No. 31078-12-3. Molecular formula: C68H106N22O17S. Mole weight: 1535.78. | |
| ALZ-801 | ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801. | |
| AM-0466 | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. | |
| AM-0687 | This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grade: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46. | |
| AM 0902 | AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain. Synonyms: AM-0902; AM 0902; AM0902. 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one. Grade: ≥98% by HPLC. CAS No. 1883711-97-4. Molecular formula: C17H15ClN6O2. Mole weight: 370.79. | |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grade: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
| AM095 | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-16039. |  |
| AM095 free acid | AM095 (free acid) is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228690-36-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-16040. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grade: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AM103 | AM 103 is a potent and selective inhibitor of FLAP, with an IC50 of 4.2 nM. Synonyms: 1H-Indole-2-propanoic acid, 3-[(1,1-dimethylethyl)thio]-1-[[4-(6-methoxy-3-pyridinyl)phenyl]methyl]-α,α-dimethyl-5-(2-pyridinylmethoxy)-, sodium salt (1:1); Sodium 3-{1-[4-(6-methoxy-3-pyridinyl)benzyl]-3-[(2-methyl-2-propanyl)sulfanyl]-5-(2-pyridinylmethoxy)-1H-indol-2-yl}-2,2-dimethylpropanoate. Grade: 95%. CAS No. 1147872-22-7. Molecular formula: C36H38N3NaO4S. Mole weight: 631.76. | |
| AM-114 | AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells. Uses: Anticancer. Synonyms: AM-114; AM 114; AM114; Proteasome Inhibitor IX; ((1Z,1'Z)-(1-methyl-4-oxopiperidine-3,5-diylidene)bis(methanylylidene))bis(4,1-phenylene))diboronic acid. Grade: 98%. CAS No. 856849-35-9. Molecular formula: C20H21B2NO5. Mole weight: 377.01. | |
| AM 1172 | AM 1172, an AEA analogue, has been found to be an anandamide uptake inhibitor as well as a cannabinoid receptor partial agonist. Synonyms: AM 1172; AM1172; AM-1172; N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide. Grade: ≥98% by HPLC. CAS No. 251908-92-6. Molecular formula: C27H39NO2. Mole weight: 409.60. | |
| AM 1172 | AM 1172. Group: Biochemicals. Grades: Purified. CAS No. 251908-92-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AM12 | AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 3,5,7-Trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 2-(2-bromophenyl)-3,5,7-trihydroxy-; AM 12; AM-12. Grade: ≥90%. CAS No. 2387510-84-9. Molecular formula: C15H9BrO5. Mole weight: 349.13. | |
| AM 12 | AM 12 is a TRPC5 inhibitor with an IC50 value of 0.28 μM, which exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grade: ≥97%. Molecular formula: C15H9BrO5. Mole weight: 349.14. | |
| AM1241 | AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Synonyms: AM 1241; AM-1241; (1-(Methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole); (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole. Grade: >98%. CAS No. 444912-48-5. Molecular formula: C22H22IN3O3. Mole weight: 503.33. | |
| AM-156 | Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future. Uses: Allergic rhinitis and asthma. Synonyms: AM-156; AM 156; AM156; UNII-5V9HJQ1Y75; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate; 1175525-98-0 (AM-156 free acid). Grade: 98%. CAS No. 1224977-85-8. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM-156 sodium | AM-156 is a bio-active chemical and detailed information has not been published yet. Synonyms: AM-156 sodium; AM 156 sodium; AM156 sodium; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate,UNII-5V9HJQ1Y75,1175525-98-0 (AM-156 free acid). Grade: 98%. CAS No. 1175525-98-0. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM-1638 | AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM). AM-1638 increases the expression of antioxidant molecules (HO-1 and NQO-1). AM1638 blocks Palmitate (HY-N0830)-mediated superoxide production and ER stress. AM-1638 has antidiabetic activity and improves glycemic control in BDF mice with diet-induced obesity (DIO). AM-1638 demonstrates excellent oral bioavailability (mouse, >100%; rat, 72%; and cyno, 71%)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1142214-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13467. | |
| AM 1714 | AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor. Uses: A potent and selective agonist for the cannabinoid receptor. Synonyms: AM-1714; AM 1714; AM1714; UNII-E3OY6PCU04; 6H-Dibenzo(b,d)pyran-6-one, 3-(1,1-dimethylheptyl)-1,9-dihydroxy-. Grade: ≥98%. CAS No. 335371-37-4. Molecular formula: C22H26O4. Mole weight: 354.44. | |
| AM-206 | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5-(2-((ethyl((phenylmethoxy)carbonyl)amino)methyl)-4-(trifluoromethyl)phenyl)-, sodium salt (1:1); UNII-NCZ7ZWF0CR; 1219935-54-2 (AM-206 free acid). Grade: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44. | |
| AM-206 sodium | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; UNII-NCZ7ZWF0CR; (5-(2-((N-((Benzyl)oxycarbonyl)-N-ethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid. Grade: 98%. CAS No. 1219935-54-2. Molecular formula: C25H23F3N2O4. Mole weight: 472.46. | |
| AM-2099 | AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50 = 0.16 μM) with excellent selectivity against hNav1.5 (IC50 > 30 uM). Synonyms: 4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide; AM-2099; AM2099; AM 2099. CAS No. 1443373-17-8. Molecular formula: C19H13F3N4O3S2. Mole weight: 466.46. | |
| AM-2099 | AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 with an IC50 of 0.16 μM for human Nav1.7. Uses: Scientific research. Category: Signaling pathways. CAS No. 1443373-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-100727. | |
| AM-211 | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: AM-211; AM 211; AM211; 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid,1263077-74-2 (AM-211 sodium). Grade: 98%. CAS No. 1175526-27-8. Molecular formula: C27H27F3N2O4. Mole weight: 500.51. | |
| AM-211 sodium | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: UNII-8SV621U288; 1175526-27-8(Free acid); AM-211 sodium; AM 211 sodium; AM211 sodium. Grade: 98%. CAS No. 1263077-74-2. Molecular formula: C27H26F3N2O4Na. Mole weight: 522.50. | |
| AM-2159 | AM-2159 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AM-2159; AM 2159; AM2159; N6-((4-chlorophenyl)methyl)-N6-methyl- 2,4,6-Quinazolinetriamine. Grade: 98%. CAS No. 83654-06-2. Molecular formula: C16H16ClN5. Mole weight: 313.78. | |
| AM2201 4-Hydroxypentyl metabolite solution | AM2201 4-Hydroxypentyl metabolite solution. Uses: For analytical and research use. CAS No. 1427521-34-3. Mole weight: 375.44. EC Number: 200-659-6. Catalog: AP1427521343. |  |
| AM-2233 | AM-2233. Group: Biochemicals. Alternative Names: (2-Iodophenyl)[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]methanone; 1-[(N-Methyl-2-piperidinyl)methyl]-3-(2-iodobenzoyl)-1H-indole. Grades: Highly Purified. CAS No. 444912-75-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H23IN2O. US Biological Life Sciences. | Worldwide |
| AM-2394 | AM-2394 is a selective Glucokinase agonist (GKA), It activates GK with an EC50 value of 60 nM. AM-2394 increases the affinity of GK for glucose by approximately 10-fold. It shows moderate clearance and good oral bioavailability in animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. Uses: Diabetes. Synonyms: AM-2394; AM 2394; AM2394; 1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea. Grade: 98%. CAS No. 1442684-77-6. Molecular formula: C22H25N5O4. Mole weight: 423.47. | |
| AM251 | AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain. Synonyms: AM251; AM 251; AM-251. Grade: >98%. CAS No. 183232-66-8. Molecular formula: C22H21Cl2IN4O. Mole weight: 555.24. | |
| AM251 | AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC50 of 39 nM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183232-66-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15443. | |
| AM 251 | Inhibitor of CB1 receptors. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 183232-66-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AM 281 | AM 281 has been found to be a CB1 selective receptor cannabinoid antagonist. Synonyms: AM281; AM 281; AM-281; 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 202463-68-1. Molecular formula: C21H19Cl2IN4O2. Mole weight: 557.22. | |
| AM 281 | AM 281. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 202463-68-1. Pack Sizes: 1mg. Molecular Formula: C21H19Cl2IN4O2, Molecular Weight: 557.21. US Biological Life Sciences. | Worldwide |
| AM3102 | AM-3102 is an Oleoyl ethanolamide (OEA) analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency. The biological effects of OEA are terminated by N-acylethanolamine-hydrolyzing acid amidase and fatty-acid amide hydrolase. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 μM, respectively. Synonyms: KDS-5104; AM-3102; AM 3102; Methyl oleoylethanolamide. Grade: ≥98%. CAS No. 213182-22-0. Molecular formula: C21H41NO2. Mole weight: 339.6. | |
| AM-36 | AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotective agent with anti-oxidant activity, in neuronal cell cultures, AM-36 inhibited toxicity induced by N-methyl-D-aspartate (NMDA) and the sodium channel opener veratridine and, in addition, inhibited veratridine-induced apoptosis. Synonyms: 2,6-ditert-butyl-4-[[4-[2-(4-chlorophenyl)-2-hydroxyethyl]piperazin-1-yl]methyl]phenol; AM-36; AM 36; AM36; UNII-08OBY024NY; SCHEMBL12311270; CNSB 002; CNSB-002; CNSB002. Grade: >98%. CAS No. 199467-52-2. Molecular formula: C27H39ClN2O2. Mole weight: 459.06. | |
| AM 36 dihydrochloride | AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates. As a unique neuroprotective agent with anti-oxidant activity, in neuronal cell cultures, AM-36 inhibited toxicity induced by N-methyl-D-aspartate (NMDA) and the sodium channel opener veratridine and, in addition, inhibited veratridine-induced apoptosis. Synonyms: CNSB002; 2,6-Di-tert-butyl-4-{4-[2-(4-chloro-phenyl)-2-hydroxy-ethyl]-piperazin-1-ylmethyl}-phenol dihydrochloride. Grade: 98%. CAS No. 1246094-77-8. Molecular formula: C27H39ClN2O2.2HCl. Mole weight: 531.99. | |
| AM404 | AM-404 is a selective inhibitor of the carrier-mediated transport of anandamide without affecting anandamide hydrolysis. AEM is also an analog of arachidonyl ethanolamide (AEA) which potentiates the activity of endogenous AEA by blocking its reuptake into presynaptic neurons. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo. Synonyms: 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (5Z,8Z,11Z,14Z)-; (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide; 5,8,11,14-Eicosatetraenamide, N-(4-hydroxyphenyl)-, (all-Z)-; AM 404; AM404. Grade: ≥98%. CAS No. 183718-77-6. Molecular formula: C26H37NO2. Mole weight: 395.58. | |
| AM 404 | AM 404. Group: Biochemicals. Grades: Purified. CAS No. 198022-70-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AM 404-d4 | It is a labeled metabolite of the well-known analgesic Paracetamol. Group: Biochemicals. Alternative Names: (5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide; (all-Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AM 404 (in Tocrisolve 100) | AM 404 (in Tocrisolve 100). Group: Biochemicals. Grades: Purified. CAS No. 198022-70-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| AM 4113 | AM4113 has been found to be a CB1 antagonist and could be used in studies of some neuronal dendritic abnormalities diseases. Synonyms: AM 4113; AM-4113; AM4113; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide. Grade: ≥98% by HPLC. CAS No. 614726-85-1. Molecular formula: C17H12Cl3N3O. Mole weight: 380.66. | |
| AM 4299 A | AM 4299 A is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: Oxiranecarboxylic acid, 3-(((1-(((5-hydroxypentyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-. Grade: >98%. CAS No. 160825-48-9. Molecular formula: C15H26N2O6. Mole weight: 330.38. | |
| AM 4299 B | AM 4299 B is a thiol protease inhibitor produced by Chromelosporium fulvum M4299. Synonyms: N(sup 6)-(N-((3-Carboxyoxiranyl)carbonyl)-L-leucyl)-L-lysine hydrate. Grade: >98%. CAS No. 160825-49-0. Molecular formula: C16H27N3O7. Mole weight: 373.40. | |
| AM4668 | AM4668 is a potent and selective G-protein coupled receptor 40(GPR40) agonist with EC50 value of 3.6 nM in an IP3 assay in GPR40 transfected A9 cells. It is more potent than AMG 837 and possesses excellent pharmacokinetic properties across species. It could reduce the plasma glucose levels in an OGTT study in human GPR40 knock-in mice. It inhibits insulin secretion from isolated pancreatic islets. Uses: Am4668 could reduce the plasma glucose levels in an ogtt study. it inhibits insulin secretion from isolated pancreatic islets. Synonyms: AM-4668; AM 4668; AM4668 ; (S)-3-(isoxazol-3-yl)-3-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)phenyl)propanoic acid; (βS)-β-[4-[[4-Methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl)-3-isoxazolepropanoic acid. Grade: >98 %. CAS No. 1011531-27-3. Molecular formula: C24H19F3N2O4S. Mole weight: 488.48. | |
| AM-5308 | AM-5308 is the inhibitor for KIF18A (IC50=47 nM) that inhibits KIF18A-mediated microtubule ATPase activity. AM-5308 activates mitotic checkpoints, regulates cell division processes, including chromosome segregation and spindle assembly. AM-5308 exhibits antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2410796-89-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144894. | |
| AM580 | AM580 is a retinoic acid receptor agonist with Kd values of 8 nM, 131 nM and 450 nM for RARα, RARβ and RARγ. Group: Inhibitors. Alternative Names: CD336; NSC608001; Ro 40-6055. CAS No. 102121-60-8. Pack Sizes: 5mg. Product ID: S2933. Formula: C22H25NO3. Smiles: CC1(CCC(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)(C)C)C. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| AM580 | AM580 is a selective RARα agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CD336; NSC608001; Ro 40-6055. CAS No. 102121-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10475. | |
| AM580 | AM580 is a selective RARα agonist. It was shown to induce differentiation of human induced pluripotent stem cells into intermediate mesoderm. Synonyms: AM-580; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]benzoic acid. Grade: >98%. CAS No. 102121-60-8. Molecular formula: C22H25NO3. Mole weight: 351.44. | |
| AM 580 | AM 580. Group: Biochemicals. Grades: Purified. CAS No. 102121-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AM 630 | AM 630. Group: Biochemicals. Alternative Names: [6-Iodo-2-methyl-1-[2- (4-morpholinyl) ethyl]-1H-indol-3-yl] (4-methoxyphenyl) methanone; Iodopravadoline. Grades: Highly Purified. CAS No. 164178-33-0. Pack Sizes: 5mg. Molecular Formula: C23H25IN2O3, Molecular Weight: 504.36. US Biological Life Sciences. | Worldwide |
| AM-643 | AM-643 is an active molecular. In the Biological Tests, it can inhibit FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA and the activity value is 0.081μM. It can also Inhibit COX1-mediated TXB2 production in human whole blood after 30 mins by competitive enzyme immunoassay and the activity value is 25μM. Synonyms: AM-643 Free Acid; AM643 Free Acid; UNII-55668SZQ3E; 3-(3-(tert-butylthio)-1-(4-(5-methoxypyrimidin-2-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid. Grade: 98%. CAS No. 1233114-22-1. Molecular formula: C36H40N4O4S. Mole weight: 642.79. | |
| AM6545 | AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist (Ki=1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1245626-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110206. | |
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