A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Amino-modifier-C2-dT CEP is an indispensable compound harnessed within the biomedical domain, deftly altering nucleotides. Its applications, extensive in scope, encompass the research of DNA and RNA for diagnostic, therapeutic and investigatory objectives. Synonyms: 5'-O-[Bis(4-Methoxyphenyl)Phenylmethyl]-2'-Deoxy-5-[3-Oxo-3-[[2-[(Trifluoroacetyl)Amino]Ethyl]Amino]-1-Propenyl]-Uridine 3'-[2-Cyanoethyl Bis(1-Methylethyl)Phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-oxo-3-[[2-[(trifluoroacetyl)amino]ethyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite](9CI). Grade: >97% by HPLC. CAS No. 153512-22-2. Molecular formula: C46H54N6O10F3P. Mole weight: 938.94.
Amino-Modifier C6 dA
Amino-Modifier C6 dA is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dA can replace the dA residue to functionalize the target oligonucleotide. Synonyms: 5'-Dimethoxytrityl-N6-benzoyl-N8-[6-(trifluoroacetylamino)-hex-1-yl]-8-amino-2'-deoxyadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMTr-8-C6-linker-TFA-2'-deoxy-3'-O-CEP-adenosine; Amino Modifier C6-dA CE-Phosphoramidite. Grade: ≥95%. CAS No. 1301170-09-1. Molecular formula: C55H65F3N9O8P. Mole weight: 1068.14.
Amino-Modifier C6 dC
Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide. Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-[(dimethylamino)methylene]-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Amino-Modifier C6 dC CEP; Amino-modifier-C6-dC-CE-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 853955-92-7. Molecular formula: C53H68F3N8O9P. Mole weight: 1049.12.
Amino-Modifier C6 dC(N-Bz) CE Phosphoramidite
Amino-Modifier C6 dC(N-Bz) CE Phosphoramidite is a phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of an amino group at the 5-position of deoxycytidine (dC). The amino group is protected by a trifluoroacetyl (TFA) group, which can be removed post-synthesis to facilitate conjugation with labels (e.g., fluorophores, biotin) via amide bond formation. A C6 spacer arm provides a six-carbon linker between the amino group and the nucleotide backbone, optimizing accessibility for subsequent reactions while minimizing steric hindrance. It is particularly useful for applications requiring internal or 5'-terminal amino modifications in oligonucleotides, such as molecular probes, diagnostic assays, or therapeutics. Synonyms: Amino-Modifier C6 dC(N-Bz) Phosphoramidite; Amino-Modifier C6 dC(Bz) CE Phosphoramidite. Grade: ≥97%. Molecular formula: C57H67F3N7O10P. Mole weight: 1098.17.
Amino-Modifier C6 dT
Amino-Modifier C6 dT is a pivotal aspect, serving as a prized instrument for conducting comprehensive nucleic acid investigations. This extraordinary compound has played a crucial role in augmenting the realm of pharmaceutical transport mechanisms and diagnostic apparatuses. Synonyms: Amino-modifier C6 dT CE Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[(1E)-3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]uridine; Amino-modifier C6 dT Phosphoramidite; Amino-Modifier C6 dT CEP. Grade: 95%. CAS No. 210534-16-0. Molecular formula: C50H62F3N6O10P. Mole weight: 995.03.
Amino-Modifier C7 CE Phosphoramidite
Amino-Modifier C7 CE Phosphoramidite is a valuable recompound acting as a versatile building block in the chemical research and development of modified nucleic acids. This compound plays a crucial role in creating oligonucleotides for applications such as gene expression analysis, DNA sequencing and antisense therapeutics. Its introduction enhances the stability and specificity of these nucleic acid-based drugs. Grade: >95% by HPLC. Molecular formula: C52H62N3O7P. Mole weight: 872.06.
Amino-Modifier Serinol Phosphoramidite
Amino-Modifier Serinol Phosphoramidite, a chemical reagent synonymous with biomedical synthesis, plays a key role in the modification of oligonucleotides - mercifully, chock-full of amino functionalities. As a potent building block, this product holds potential for therapeutic and diagnostic development, with applications pertaining to the likes of cancer, viral infections, and genetic disorders. Well-renowned for its high purity and stability, it remains a stand-out performer in the realm of gene therapy and all matters nucleic acid drug delivery. Synonyms: 3-Dimethoxytrityloxy-2-(3-(fluorenylmethoxycarbonylamino)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 9-Oxa-2,6,11-triaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9,11-Dioxa-2,6-diaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9H-Fluoren-9-ylmethyl 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-9-oxa-2,6,11-triaza-10-phosphatridecanoate. CAS No. 196297-83-3. Molecular formula: C51H59N4O8P. Mole weight: 887.01.
aminomuconate-semialdehyde dehydrogenase
Also acts on 2-hydroxymuconate semialdehyde. Group: Enzymes. Synonyms: 2-aminomuconate semialdehyde dehydrogenase; 2-hydroxymuconic acid semialdehyde dehydrogenase; 2-hydroxymuconate semialdehyde dehydrogenase; α-aminomuconic ε-semialdehyde dehydrogenase; α-hydroxymuconic ε-semialdehyde dehydrogenase; 2-hydroxymuconic semialdehyde dehydrogenase. Enzyme Commission Number: EC 1.2.1.32. CAS No. 37250-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1139; aminomuconate-semialdehyde dehydrogenase; EC 1.2.1.32; 37250-95-6; 2-aminomuconate semialdehyde dehydrogenase; 2-hydroxymuconic acid semialdehyde dehydrogenase; 2-hydroxymuconate semialdehyde dehydrogenase; α-aminomuconic ε-semialdehyde dehydrogenase; α-hydroxymuconic ε-semialdehyde dehydrogenase; 2-hydroxymuconic semialdehyde dehydrogenase. Cat No: EXWM-1139.
Amino-naphthalen-1-yl-acetic acid
Amino-naphthalen-1-yl-acetic acid. Group: Biochemicals. Alternative Names: 2-Amino-2-(naphthalen-4-yl)acetic acid. Grades: Highly Purified. CAS No. 97611-60-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Amino-naphthalen-1-yl-acetic acid ≥95% (NMR)
Amino-naphthalen-1-yl-acetic acid ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Amino(naphthalen-2-yl)acetic acid
Amino(naphthalen-2-yl)acetic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 33741-78-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Amino Nimesulide NAC Adduct Sodium Salt
Amino Nimesulide NAC Adduct Sodium Salt is an impurity of Nimesulide, which is a selective COX-2 inhibitor. Synonyms: N-Acetyl-S-[2-amino-5-[(methylsulfonyl)amino]-4-phenoxyphenyl]-L-cysteine Sodium Salt; sodium N-acetyl-S-(2-amino-5-(methylsulfonamido)-4-phenoxyphenyl)-L-cysteinate; L-Cysteine, N-acetyl-S-[2-amino-5-[(methylsulfonyl)amino]-4-phenoxyphenyl]-, sodium salt (1:1). Grade: ≥95%. CAS No. 1798888-56-8. Molecular formula: C18H20N3NaO6S2. Mole weight: 461.49.
Amino Nimesulide NAC Adduct Sodium Salt
Amino Nimesulide NAC Adduct Sodium Salt. Group: Biochemicals. Alternative Names: N-Acetyl-S-[2-amino-5-[ (methylsulfonyl)amino]-4-phenoxyphenyl]-L-cysteine Sodium Salt. Grades: Highly Purified. CAS No. 1094566-35-4. Pack Sizes: 1mg. Molecular Formula: C18H20N3NaO6S2, Molecular Weight: 461.49. US Biological Life Sciences.
Worldwide
Amino Oxibendazole HCl
Amino Oxibendazole HCl is a derivative of the Oxibendazole which is used as an anthelmintic. Synonyms: N-(Demethyl Formate) Oxibendazole Hydrochloride; 6-Propoxy-1H-benzimidazol-2-amine Hydrochloride (1:1). Grade: > 95%. CAS No. 1538624-34-8. Molecular formula: C10H13N3O.HCl. Mole weight: 191.23.
Aminooxyacetic Acid
Aminooxyacetic acid, often abbreviated AOA or AOAA, is a GABA transaminase (GABA-T) inhibitor (Ki = 9.16 μM) that inhibits 4-aminobutyrate aminotransferase (GABA-T) activity in vitro and in vivo, leading to less gamma-aminobutyric acid (GABA) being broken down. Subsequently, the level of GABA is increased in tissues. At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a useful tool to study regional GABA turnover in rats. AOAA is also an inhibitor of pyridoxal phosphate (PLP)-dependent enzymes, which serve as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes. Uses: Gaba agents. Synonyms: Aminooxyacetate; AOAA; 2-Aminooxyacetic acid; U 7524; U7524; U-7524. Grade: ≥95%. CAS No. 645-88-5. Molecular formula: C2H5NO3. Mole weight: 91.07.
Aminooxyacetic acid hemihydrochloride
Aminooxyacetic acid (Carboxymethoxylamine) hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carboxymethoxylamine hemihydrochloride; Aminooxyacetate hemihydrochloride. CAS No. 2921-14-4. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-107994.
Aminooxy-modifier CEP
Aminooxy-modifier CEP is used in oxime ligation for peptide-oligonucleotide conjugates, attachment of nucleosides to solid supports, and head to tail cyclization of oligonucleotides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1393581-75-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C47H58N3O11P, Molecular Weight: 871.95. US Biological Life Sciences.
Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1306615-51-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126949.
Aminooxy-PEG4-azide
Aminooxy-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminooxy-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2100306-61-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126950.
Aminooxy-PEG5-azide
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminooxy-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1919045-02-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130507.
Amino-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415408-69-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140177.
Amino-PEG24-acid
Amino-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2563873-76-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140182.
Amino-PEG2-CH2CH2-SH hydrochloride
Amino-PEG2-CH2CH2-SH (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3037676-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132120.
Amino-PEG2-NH-Boc
Amino-PEG2-NH-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 127828-22-2. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W008279.
Amino-PEG3-C2-acid is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG3-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 784105-33-5. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W040165.
Amino-PEG3-C2-Azido
Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645)[1]. Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 134179-38-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W021401.
Amino-PEG3-C2-sulfonic acid
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1817735-43-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140001.
Applications in medical research, drug-release, nanotechnology, materials research and cell culture. In the study of ligand, polypeptide synthesis support, graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. Group: Biochemicals. Alternative Names: NH2-PEG3-CH2CH2COOtBu. Grades: Highly Purified. CAS No. 252881-74-6. Pack Sizes: 5g. Molecular Formula: C13H27NO5, Molecular Weight: 277.4. US Biological Life Sciences.
Worldwide
Amino-PEG4-alcohol
Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86770-74-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W008005.
Amino-PEG4-Boc
Amino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 581065-95-4. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-140193.
Amino-PEG4-GGFG-Dxd
Amino-PEG4-GGFG-Dxd (Compound 13-7) is a drug-linker conjugate for ADC. Amino-PEG4-GGFG-Dxd is composed of Dxd (HY-13631D) and a linker. Amino-PEG4-GGFG-Dxd can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2879227-88-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-158768.
Amino-PEG4-Val-Cit-PAB-MMAE
Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1492056-71-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-141154.
Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 39160-70-8. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-126942.
Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 82209-36-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-130659.
Amino-PEG8-Boc
Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756526-06-4. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W019799.
Cytosolic or membrane-associated enzyme from mammalian tissues, activated by chloride ions and low concentrations of thiol compounds. This is one of the activities of the bifunctional enzyme EC 3.3.2.6 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Enzyme Commission Number: EC 3.4.11.6. CAS No. 9073-92-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4027; aminopeptidase B; EC 3.4.11.6; 9073-92-1; arylamidase II; arginine aminopeptidase; arginyl aminopeptidase; Cl--activated arginine aminopeptidase; cytosol aminopeptidase IV; L-arginine aminopeptidase. Cat No: EXWM-4027.
aminopeptidase Ey
A zinc glycoprotein in peptidase family M1 (membrane alanyl aminopeptidase family), composed of two 150 kDa subunits. From the plasma fraction of hen egg yolk. Group: Enzymes. Enzyme Commission Number: EC 3.4.11.20. CAS No. 9031-94-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4017; aminopeptidase Ey; EC 3.4.11.20; 9031-94-1. Cat No: EXWM-4017.
Aminopeptidase from Aeromonas, Recombinant
Aeromonas Aminopeptidase is used in the processing of pharmaceutical proteins produces by genetic engineering as well as for physical and structural investigations and for sequence and amino-terminal determinations. This exopeptidase recognizes a specific stop sign at -X-Pro and requires a free a-amino group in the L-configuration. It is therefore suitable for the removal of the redundant N-terminal methionine often added to engineered recombinant proteins. Group: Enzymes. Synonyms: Aeromonas Aminopeptidase; Aminopeptidase. Aminopeptidase. Activity: 120 Units/mg protein. Stability: Two years when stored at -20°C, 2 weeks at 4°C. Please avoid freeze-thaw cycles. Appearance: Sterile filtered liquid formulation. Source: Aeromonas. Aeromonas Aminopeptidase; Aminopeptidase. Cat No: NATE-0811.
aminopeptidase I
A 640-kDa, dodecameric enzyme best known as the major vacuolar aminopeptidase of yeast, Saccharomyces cervisiae, in which species it was first given the name aminopeptidase I (one), amongst others. Activity is stimulated by both Zn2+ and Cl- ions. Type example of peptidase family M18. Group: Enzymes. Synonyms: aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Enzyme Commission Number: EC 3.4.11.22. CAS No. 9031-94-1. Aminopeptidase I. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4019; aminopeptidase I; EC 3.4.11.22; 9031-94-1; aminopeptidase III; aminopeptidase yscI; leucine aminopeptidase IV; yeast aminopeptidase I. Cat No: EXWM-4019.
Aminopeptidase M
Inhibition of aminopeptidase M (AMP) is being studied for its potential to treat various diseases, including aggressively growing cancer types that have a high degree of blood vessel formation. Synonyms: Microsomal aminopeptidase; Aminopeptidase, microsomal; L-Alanine aminopeptidase; L-Alanylaminopeptidase; Alanine aminopeptidase (3.4.11.2); Alanine aminopeptidases; Alanine-specific aminopeptidase; Alanine-specific aminopeptidases; Alanyl aminopeptidase; Alanyl aminopeptidases; Aminopeptidase M (EC 3.4.11.2); Aminopeptidase M 2; Aminopeptidase M II; Aminopeptidase N; Aminopeptidase N (EC 3.4.11.2); Aminopeptidase PepN; ANPEP; Antigens, CD13; Brush border membrane antigen CD13; CD antigens, CD13; CD13; CD13 antigen; CD13 antigens; Membrane alanyl aminopeptidase; Microsomal aminopeptidases; Myeloid plasma membrane glycoprotein CD13; PepN; Peptidase M; Vp165 aminopeptidase; Vp165 aminopeptidases; Leucine Aminopeptidase, microsomal from porcine kidney. CAS No. 9054-63-1. Molecular formula: C57H41N5Si. Mole weight: 824.1.
Aminopeptidase N Inhibitor
Membrane alanyl aminopeptidase is also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N), which is an enzyme that in humans is encoded by the ANPEP gene. Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM). It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. Synonyms: AP-N Inhibitor. Grade: ≥95%. CAS No. 596108-59-7. Molecular formula: C17H10N2O8. Mole weight: 370.27.
Aminopeptidase N Ligand (CD13), NGR peptide
It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 and cys5, and is known to have antimicrobial properties in addition to the presence of KLA sequences. The peptide binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. This peptide shows dose-dependent antiproliferation against tumor cells and induces cell cylce arrest at G2/M phases and apoptosis of the tumor cells. Peptides containing the NGR motif are useful in the delivery of cytotoxic drugs, pro-apoptotic peptides, and tumor necrosis factor (TNF) into tumor vasculature. Synonyms: H-Cys-Asn-Gly-Arg-Cys-Gly-OH (Disulfide bridge: Cys1-Cys5); L-cysteinyl-L-asparagyl-glycyl-L-arginyl-L-cysteinyl-glycine (1->5)-disulfide; N-{[(4R,5E,7S,8E,11E,13S,14E,16R)-16-Amino-7-(3-carbamimidamidopropyl)-6,9,12,15-tetrahydroxy-13-(2-hydroxy-2-iminoethyl)-1,2-dithia-5,8,11,14-tetraazacycloheptadeca-5,8,11,14-tetraen-4-yl](hydroxy)methylene}glycine. Grade: ≥95%. Molecular formula: C20H34N10O8S2. Mole weight: 606.67.
aminopeptidase S
Aminopeptidases are associated with many biological functions, including protein maturation, protein degradation, cell-cycle control and hormone-level regulation. This enzyme contains two zinc molecules in its active site and is activated by Ca2+. In the presence of Ca2+, the best substrates are Leu-Phe, Leu-Ser, Leu-pNA (aminoacyl-p-nitroanilide), Phe-Phe-Phe and Phe-Phe. Peptides with proline in the P1' position are not substrates. Belongs in peptidase family M28. Group: Enzymes. Synonyms: Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Enzyme Commission Number: EC 3.4.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4021; aminopeptidase S; EC 3.4.11.24; Mername-AA022 peptidase; SGAP; aminopeptidase (Streptomyces griseus); Streptomyces griseus aminopeptidase; S. griseus AP; double-zinc aminopeptidase. Cat No: EXWM-4021.
aminopeptidase Y
Requires Co2+; inhibited by Zn2+ and Mn2+. An enzyme best known from Saccharomyces cerevisiae that hydrolyses Lys-NHPhNO2 and, more slowly, Arg-NHPhNO2. Type example of peptidase family M28. Group: Enzymes. Synonyms: aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Enzyme Commission Number: EC 3.4.11.15. CAS No. 114796-97-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4011; aminopeptidase Y; EC 3.4.11.15; 114796-97-3; aminopeptidase Co; aminopeptidase (cobalt-activated); lysyl aminopeptidase. Cat No: EXWM-4011.
100g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H8N4O2 ·0.5C2H8N2. CAS No. 317-34-0. Prepack ID 17877086-100g. Molecular Weight 210.21. See USA prepack pricing.
Aminophylline
Aminophylline. Alternative Names: Theophyllamine. CAS No. 317-34-0. Purity: 98%+. Product ID: ACM317340. Molecular formula: C14H16N8O4·C2H8N2. Mole weight: 420.43. IUPAC Name: Aminophylline. Alfa Chemistry - ISO 9001:32057 Certified.
Aminophylline
Aminophylline is a bronchodilator and a non-selective phosphodiesterase (PDE) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 317-34-0. Pack Sizes: 1g, 10g, 50g, 100g, 500g. Molecular Formula: C?H?N?O?; 1/2 C ?H?N?. US Biological Life Sciences.
Worldwide
Aminophylline
Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist. Synonyms: Phyllocontin. Grade: >98%. CAS No. 317-34-0. Molecular formula: C16H24N10O4. Mole weight: 420.43.