A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. Synonyms: CP 65703; CP65703; CP-65703. Grade: >98%. CAS No. 99464-64-9. Molecular formula: C20H21N3O7S. Mole weight: 447.46.
Ampiroxicam
Prodrug of Piroxicam. Anti-inflammatory. Group: Biochemicals. Alternative Names: Carbonic Acid Ethyl 1-[[2-Methyl-1, 1-dioxido-3-[ (2-pyridinylamino) carbonyl]-2H-1, 2-benzothiazin-4-yl]oxy]ethyl Ester; CP 65703; Flucam; Nasil. Grades: Highly Purified. CAS No. 99464-64-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AMPK activator
AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. D942 is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, which shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 μM). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Because of the favorable physiological outcomes of AMPK activation on metabolism, AMPK has been considered to be an important therapeutic target for controlling human diseases including metabolic syndrome and cancer. Synonyms: D942; AMPK activator; 5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]furan-2-carboxylic Acid. Grade: ≥95%. CAS No. 849727-81-7. Molecular formula: C22H21FO4. Mole weight: 368.4.
AMPK activator 1
AMPK activator 1 is an AMPK activator extracted from patent WO2013116491A1 (compound No.1-75, EC50 < 0.1μM). Synonyms: 2-Benzofurancarboxamid?e, N-[1-(4-pyridinylmethyl)?-4-piperidinyl]?-5-[[1-[4-(trifluoromethyl)?phenyl]?-4-piperidinyl]?oxy]?-. CAS No. 1152423-98-7. Molecular formula: C32H33F3N4O3. Mole weight: 578.62.
AMPK activator 4
AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. Anti-hyperglycemic effect. Synonyms: AMPK activator 4; 2493239-46-4; CHEMBL4798218; MS-27389; HY-131334; CS-0133422; 2-(4-chlorophenoxy)-N-[4-[(4-cyanophenyl)methoxy]phenyl]-2-methylpropanamide. Grade: 99%. CAS No. 2493239-46-4. Molecular formula: C24H21ClN2O3. Mole weight: 420.89.
AMPK activator 4
AMPK activator 4 is a potent AMPK activator without inhibition of mitochondrial complex I. AMPK activator 4 selectively activates AMPK in the muscle tissues. AMPK activator 4 dose-dependently improves glucose tolerance in normal mice, and significantly lowers fasting blood glucose level and ameliorates insulin resistance in db/db diabetic mice. Anti-hyperglycemic effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2493239-46-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131334.
AMPK-IN-3 (compound 67) is a potent and selective AMPK inhibitor with IC50s of 60.7, 107 and 3820 nM for AMPK (α2), AMPK (α1) and KDR, respectively. AMPK-IN-3 inhibits AMPK does not affect cell viability or cause significant cytotoxicity in K562 cells. AMPK-IN-3 can be used in study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417674-27-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151361.
AMPK-IN-4
AMPK-IN-4 (compound 19) is a potent inhibitor of (AMPK(α1) and AMPK(α2) with IC50s of 393 nM and 141 nM, respectively. AMPK-IN-4 plays an important role in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 873077-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155943.
Ampkinone
Ampkinone, an AMPK activitor, has been found to have potential effect in the treatment of diabete and obesity. IC50: 4.3 uM(EC50). Uses: Ampkinone is an ampk activitor that has been found to have potential effect in the treatment of diabete and obesity. Synonyms: 2-(4-Benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione. Grade: 98%. CAS No. 1233082-79-5. Molecular formula: C31H23NO6. Mole weight: 505.52.
Ampkinone
Ampkinone is an indirect AMP-activated protein kinase (AMPK) activator. Uses: Scientific research. Category: Signaling pathways. CAS No. 1233082-79-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg. Product ID: HY-12831.
Ampkinone
Ampkinone. Group: Biochemicals. Alternative Names: 2-(4-Benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione. Grades: Highly Purified. CAS No. 1233082-79-5. Pack Sizes: 2.5mg. Molecular Formula: C31H23NO6, Molecular Weight: 505.52. US Biological Life Sciences.
This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is AMP phosphoribohydrolase. Other names in common use include adenylate nucleosidase, and adenosine monophosphate nucleosidase. This enzyme participates in purine metabolism. Group: Enzymes. Synonyms: adenylate nucleosidase; adenosine monophosphate nucleosidase. Enzyme Commission Number: EC 3.2.2.4. CAS No. 9025-45-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3986; AMP nucleosidase; EC 3.2.2.4; 9025-45-0; adenylate nucleosidase; adenosine monophosphate nucleosidase. Cat No: EXWM-3986.
AMP-PCP
AMP-PCP is an ATP analogue and can bind to the N-terminal domain of Hsp90 with a Kd of 3.8 μM. AMP-PCP binding is beneficial to the formation of Hsp90 active homodimer. Synonyms: Phosphomethylphosphonic acid adenylate ester; L-betagamma-meATP; beta,gamma-Methylene ATP; 5'-O-(Hydroxy{[hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl)adenosine; 5'-adenylic acid, monohydride with methylenebis(phosphonic acid); 5'-adenylyl (β,γ-methylene)diphosphonate; 9H-Purin-6-amine, 9-[5-O-[hydroxy[[hydroxy(phosphonomethyl)phosphinyl]oxy]phosphinyl]-β-D-ribofuranosyl]-. Grade: ≥95%. CAS No. 3469-78-1. Molecular formula: C11H18N5O12P3. Mole weight: 505.21.
AMP-PCP disodium
AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a Kd value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7414-56-4. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-106723A.
AMP phosphorylase
The enzyme from archaea is involved in AMP metabolism and CO2 fixation through type III RubisCO enzymes. The activity with CMP and UMP requires activation by cAMP. Group: Enzymes. Synonyms: AMPpase; nucleoside monophosphate phosphorylase; deoA (gene name). Enzyme Commission Number: EC 2.4.2.57. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2687; AMP phosphorylase; EC 2.4.2.57; AMPpase; nucleoside monophosphate phosphorylase; deoA (gene name). Cat No: EXWM-2687.
AMP PNP
AMP PNP is an analogue of AMP and has been found to be a Kir6 (KATP) channel blocker. Synonyms: Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt. Grade: ≥90% by HPLC. CAS No. 72957-42-7. Molecular formula: C10H13Li4N6O12P3. Mole weight: 529.93.
AMP-PNP tetralithium
AMP-PNP (Adenylyl-imidodiphosphate) tetralithium is a non-hydrolyzable ATP analog. AMP-PNP tetralithium binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP tetralithium can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adenylyl-imidodiphosphate tetralithium. CAS No. 72957-42-7. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg. Product ID: HY-128933.
Amprenavir
Amprenavir was a protease inhibitor used in the treatment of HIV-1 infection, developed as a second-generation agent with once-daily potential. Applications: Amprenavir was indicated in combination with other antiretrovirals for the treatment of hiv-1 infection in adults and children. Category: Active pharmaceutical ingredients. Synonyms: Agenerase; VX-478; Prozei; 141W94; KVX-478. CAS No. 161814-49-9. Product ID: API0231597. Molecular formula: C25H35N3O6S. Mole weight: 505.6. EINECS: 827-179-5. InChIKey: YMARZQAQMVYCKC-OEMFJLHTSA-N. Appearance: White to beige powder.
Amprenavir
Amprenavir. Group: Biochemicals. Alternative Names: N-[ (1S, 2R) -3-[[ (4-Aminophenyl) sulfonyl] (2-methylpropyl) amino]-2-hydroxy-1- (phenylmethyl) propyl]carbamic acid (3S)-tetrahydro-3-furanyl ester; 141W94; KVX-478. Grades: Highly Purified. CAS No. 161814-49-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C25H35N3O6S. US Biological Life Sciences.
Worldwide
Amprenavir
Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP. Uses: Amprenavir is indicated in combination with other antiretroviral agents in the treatment of hiv-1 infection. Synonyms: VX-478; VX 478; VX478; Amprenavir; Agenerase; Prozei. Grade: >98%. CAS No. 161814-49-9. Molecular formula: C25H35N3O6S. Mole weight: 505.63.
Amprenavir
Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VX-478. CAS No. 161814-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17430.
Amprenavir-d4
Labeled Amprenavir, a selective HIV protease inhibitor. An analogue of Ritonavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Amprenavir-[d4]
Amprenavir-[d4] is a labelled analogue of Amprenavir. Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP. Synonyms: Amprenavir-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1217661-20-5. Molecular formula: C25H31D4N3O6S. Mole weight: 509.65.
Amprolium
Amprolium, a thiamine derivative, could be commonly useful in poultry as a coccidiostat. Uses: Amprolium could be commonly useful in poultry as a coccidiostat. Synonyms: Amprolium; Amprolio; Amprolium[ban:inn]; Amprolium [INN-Latin]; Amprolio [INN-Spanish]. Grade: 98%. CAS No. 121-25-5. Molecular formula: C14H19ClN4. Mole weight: 278.78.
Amprolium hydrochloride
Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake. Uses: Coccidiostats. Synonyms: Amprol; Amprol 25; Thiacoccid; NSC 523454; NSC523454; NSC-523454; Amprolium HCl; amprolium; Mepyrium; 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine chloride hydrochloride. Grade: >98%. CAS No. 137-88-2. Molecular formula: C14H20Cl2N4. Mole weight: 315.242.
Amprolium hydrochloride
Amprolium hydrochloride. Alternative Names: 1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium Chloride Hydrochloride. CAS No. 137-88-2. Purity: >98.0%. Product ID: FFC-AR-137882. Molecular formula: C14H20Cl2N4. Mole weight: 315.24. IUPAC Name: 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine;chloride;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified.
Amprolium hydrochloride
25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C14H19ClN4 ·HCl. CAS No. 137-88-2. Prepack ID 67107023-25g. Molecular Weight 315.24. See USA prepack pricing.
Amprolium hydrochloride
Amprolium hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 137-88-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. US Biological Life Sciences.
100g Pack Size. Group: Buffers. Formula: C7H17NO5S. CAS No. 68399-79-1. Prepack ID 17283132-100g. Molecular Weight 227.28. See USA prepack pricing.
AMP-thymidine kinase
The deoxypyrimidine kinase complex induced by Herpes simplex virus catalyses this reaction as well as those of EC 2.7.1.21 (thymidine kinase), EC 2.7.1.118 (ADP-thymidine kinase) and EC 2.7.4.9 (dTMP kinase). Group: Enzymes. Synonyms: adenylate-nucleoside phosphotransferase. Enzyme Commission Number: EC 2.7.1.114. CAS No. 60440-28-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2957; AMP-thymidine kinase; EC 2.7.1.114; 60440-28-0; adenylate-nucleoside phosphotransferase. Cat No: EXWM-2957.
AMPTX-1
AMPTX-1 is a selective, orally active, covalent reversible BRD9 molecular glue degrader with a DC50 of 0.05 nM. AMPTX-1 selectively recruits BRD9 to the E3 ligase DCAF16. AMPTX-1 forms a ternary complex with BRD9 and a reversible covalent adduct with Cys58 on the surface of DCAF16. AMPTX-1 mediates BRD9 degradation via the proteasome and Cullin RING E3 ligase pathways. AMPTX-1 can be used in the research of solid tumors and hematological malignancies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033019-04-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-172615.
Ampullosporin A is produced by the strain of Sepedonium ampullosporum HKI-0053. Its antibacterial spectrum is narrow. The anti-staphylococcus aureus GS511, Bacillus subtilis, Pseudomonas aeruginosa K599/WT, Escherichia coli SG458, Ocher sporococcus SBUG 549 and Deep red yeast and other bacteria and fungi had only moderate intensity activity, and had no effect on other yeast and candida albicans. It can cause Phoma destructiva to form pigment. Its content is greater than 1mg/kg, which can cause hypothermia and reduce automatic exercise in rats. Synonyms: N-Acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]-L-glutamamide. CAS No. 197960-94-4. Molecular formula: C77H127N19O19. Mole weight: 1622.94.
Ampyrone
Ampyrone (4-Aminophenazone; 4-Aminoantipyrine) is a reversible and low-damage optical clearing agent and non-selective COX inhibitor based on UV absorption properties. Ampyrone can improve the optical transmittance of mouse skin and other tissues. Ampyrone can induce tissue refractive index matching by enhancing UV absorption, reduce light scattering, and achieve tissue transparency in vivo. Ampyrone reduces the synthesis of prostaglandin PGE2, thereby exerting anti-inflammatory, analgesic and antipyretic effects. Ampyrone inhibits DNA damage, cell apoptosis and immune cell phagocytosis induced by Doxorubicin (HY-15142A) and Cisplatin (HY-17394), etc., and participates in the regulation of toxicity in tumor chemotherapy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Aminophenazone. CAS No. 83-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g. Product ID: HY-B1398.
Amrecibart is an anti-coagulation factor 11 human IgG4 κ monoclonal antibody. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN-9933. CAS No. 3008610-20-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991117.
Amredobresib
Amredobresib is a potent BET inhibitor that inhibits the binding of brominated domains to acetylated lysine on histones H3 and H4, and is therefore an important regulator of gene transcription. It is used in acute myeloid leukemia (AML) and cancer research. (Extracted from patent WO2019145410A1 and WO2021175824A1). Synonyms: 1,2,4-Triazolo(4,3-a)pyrazin-8-amine, N,3-dimethyl-6-(6-(4-methyl-1-piperazinyl)-1-(phenylmethyl)-1hbenzimidazol-2-yl)-; 6-(1-Benzyl-6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-N,3-dimethyl-(1,2,4)triazolo(4,3-a)pyrazin-8-amine; 6-[1-Benzyl-6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine. CAS No. 1610044-98-8. Molecular formula: C26H29N9. Mole weight: 467.57.
Amredobresib
Amredobresib (BI894999) is an orally active BET inhibitor. Amredobresib inhibits the binding of BRD4-BD1 and BRD4-BD2 bromodomains to acetylated histones with IC50 values of 5 nM and 41 nM, respectively. Amredobresib exhibits anticancer activity against acute myeloid leukemia (AML) and NUT cancer[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI894999. CAS No. 1610044-98-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145550.
AMRI-59
AMRI-59 is a potent inhibitor of PrxI with anti-tumor activity. Synonyms: 4-(4-(1H-pyrrol-1-yl)benzyl)-N-(3-acetylphenyl)piperidine-1-carboxamide. CAS No. 923515-92-8. Molecular formula: C25H27N3O2. Mole weight: 401.50.
Amrinone
Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Synonyms: Inamrinone; Wincoram; Inocor; Cordemcura; Win-40680; Win40680; 3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. Grade: 98%. CAS No. 60719-84-8. Molecular formula: C10H9N3O. Mole weight: 187.20.
Amrinone
A selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. Cardiotonic. Group: Biochemicals. Alternative Names: 5-Amino-[3,4'-bipyridin]-6(1H)-one; 3-Amino-5-(4-pyridinyl)-1,2-dihydro-2-pyridone; 5-Amino-1,6-dihydro-6-oxo-[3,4'-bipyridine]; AWD 08-250; Cartonic; Cordemcura; Inamrinone; Vesistol; Win 40680; Wincoram. Grades: Highly Purified. CAS No. 60719-84-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Amrinone Related Compound A
Amrinone Related Compound A. Uses: For analytical and research use. CAS No. 62749-46-6. Mole weight: 215.21. Catalog: AP62749466.
Amrinone Related Compound C
Amrinone Related Compound C. Uses: For analytical and research use. CAS No. 62749-26-2. Mole weight: 197.19. Catalog: AP62749262.
Amrioclomol
Amrioclomol is a drug candidate that amplifies the production of heat shock proteins (HSPs). Synonyms: (2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol; arimoclomol. Grade: 95%. CAS No. 289893-25-0. Molecular formula: C14H20ClN3O3. Mole weight: 313.78.
Amrubicin
Amrubicin. Group: Biochemicals. Alternative Names: (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy--D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 110267-81-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C25H25NO9. US Biological Life Sciences.
Worldwide
Amrubicin-13C3
Synthetic anthracycline antibiotic; inhibits DNA topoisomerase II. Antineoplastic. Group: Biochemicals. Alternative Names: (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy- β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione-13C3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Amrubicin-13C3
Amrubicin is a synthetic anthracycline antibiotic that inhibits DNA topoisomerase II. Antineoplastic. Synonyms: (7S,9S)-9-Acetyl-9-amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-5,12-naphthacenedione-13C3. Molecular formula: C22[13C]3H25NO9. Mole weight: 486.45.
Amrubicin hydrochloride
Amrubicin hydrochloride is a topoisomerase II inhibitor used in the treatment of lung cancer. Uses: Antineoplastic agents. Synonyms: Amrubicin HCl; SM-5887; Calsed; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-9-acetyl-9-amino-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-6,11-dihydroxy-, hydrochloride, (7S-cis)-; 5,12-Naphthacenedione, 9-acetyl-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-, hydrochloride, (7S,9S)-. Grade: >98%. CAS No. 110311-30-3. Molecular formula: C25H26ClNO9. Mole weight: 519.93.
Amrubicinol-13C3 (Mixture of Diastereomers)
A labelled metabolite of Amrubicin, which is active and possesses cytotoxicity 10 to 100 times that of the parent drug. Synonyms: (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione-13C3; 13-Hydroxy SM 5887-13C3. Molecular formula: C22[13C]3H27NO9. Mole weight: 488.46.
Amrubicinol (Mixture of Diastereomers)
A metabolite of Amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Uses: A metabolite of amrubicin, which is active and possesses a cytotoxicity 10 to 100 times that of the parent drug. Synonyms: (7S,9S)-9-Amino-7-[(2-deoxy-β-D-erythro-pentopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-9-(1-hydroxyethyl)-5,12-naphthacenedione; 13-Hydroxy SM 5887. CAS No. 186353-53-7. Molecular formula: C25H27NO9. Mole weight: 485.48.
Amrubicinol (Mixture of Diastereomers)
Amrubicinol (Mixture of Diastereomers). CAS No: 186353-53-7
Sarchem Laboratories New Jersey NJ
AMS-17
AMS-17 is a potent NLRP3 inhibitor, inhibiting microglia activation in vitro and in vivo. AMS-17 also inhibits cytokines such as caspase-1, TNF-α, IL-1β and inducible nitric oxide synthase (iNOS) in N9 cells. AMS-17 can be used for researching inflammation-associated neurological disorders, such as vascular dementia (VaD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3019885-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146765.
Amsacrine
Amsacrine (m-AMSA; acridinyl anisidide) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m-AMSA; acridinyl anisidide. CAS No. 51264-14-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13551.
Amsacrine
Amsacrine is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Synonyms: AMSA; m-AMSA; CI 880, CI880, CI-880; SN-11841; SN 11841; SN11841; acridinyl anisidide. Grade: >98%. CAS No. 51264-14-3. Molecular formula: C21H19N3O3S. Mole weight: 393.46.
Amsacrine hydrochloride
Amsacrine hydrochloride is an antineoplastic agent which can intercalate into the DNA of tumor cells. It also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II. Uses: Antineoplastic agents. Synonyms: AMSA hydrochloride; m-AMSA hydrochloride; CI-880 hydrochloride; SN-11841 hydrochloride; CI 880 hydrochloride; SN 11841 hydrochloride; CI880 hydrochloride; SN11841 hydrochloride; acridinyl anisidide hydrochloride. Grade: >98%. CAS No. 54301-15-4. Molecular formula: C21H20ClN3O3S. Mole weight: 429.92.
Amsacrine hydrochloride
Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: m-AMSA hydrochloride; acridinyl anisidide hydrochloride. CAS No. 54301-15-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-13551A.
Amsacrine Impurity C
Amsacrine Impurity C. Uses: For analytical and research use. Alternative Names: Acridin-9(10H)-one. CAS No. 758-95-0. Molecular formula: C13H9NO. Mole weight: 195.22. Catalog: APB758950.
Amsalog
Asulacrine isethionate is the isethionate salt of an amsacrine analogue with antineoplastic properties. Asulacrine inhibits the enzyme topoisomerase ll, thereby blocking DNA replication and RNA and protein synthesis. Synonyms: Asulacrine isethionate; CI-921. CAS No. 80841-48-1. Molecular formula: C26H30N4O8S2. Mole weight: 590.67.
amsilarotene
Amsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. Synonyms: TAC-101; TAC 101; TAC101; Am 555S; Benzoic acid, 4-[[3,5-bis(trimethylsilyl)benzoyl]amino]-. Grade: 99%. CAS No. 125973-56-0. Molecular formula: C20H27NO3Si2. Mole weight: 385.61.
AMTB hydrochloride
The hydrochloride salt form of AMTB, which has been found to be a TRPM8 channel blocker. Synonyms: N-(3-Aminopropyl)-2-[(3-methylphenyl)methoxy]-N-(2-thienylmethyl)benzamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 926023-82-7. Molecular formula: C23H26N2O2S.HCl. Mole weight: 430.99.
AMTB hydrochloride
AMTB hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 926023-82-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AMTB hydrochloride
AMTB hydrochloride is a selective TRPM8 channel blocker. AMTB hydrochloride inhibits icilin-induced TRPM8 channel activation with a pIC50 of 6.23. AMTB hydrochloride can be used for the research of the overactive bladder and painful bladder syndrome. AMTB hydrochloride is a non-selective inhibitor of voltage-gated sodium channels (NaV)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 926023-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100345.
Amthamine dihydrobromide
Amthamine dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 142457-00-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Amthamine dihydrobromide
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and has no activity at H1 receptors. It decreases myogenic tone and induces vasodilation of cerebral arteries in vitro. It can be used in the suppression of the release of serotonin and H2 receptor-mediated eosinophil peroxidase (EPO). It has been used to study the effect of mast cells on T regulatory cell function. Synonyms: 5-(2-Aminoethyl)-4-methylthiazol-2-amine Dihydrobromide; A 4730 Dihydrobromide; 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide; 2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide. Grade: ≥99% by HPLC. CAS No. 142457-00-9. Molecular formula: C6H13N3SBr2. Mole weight: 319.06.
AMT hydrochloride
The hydrochloride salt form of AMT, which has been found to be a reversible inhibitor of iNOS and could probably be useful in treatment of inflammatory and autoimmune disorders. Synonyms: 2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine hydrochloride. Grade: ≥95% by HPLC. CAS No. 21463-31-0. Molecular formula: C5H10N2S.HCl. Mole weight: 166.67.
AMT hydrochloride
AMT hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 21463-31-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.