A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28.
Acazicolcept
Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALPN-101. CAS No. 2797026-97-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99420.
Acazicolcept
Acazicolcept is a dual ICOS/CD28 antagonist. It decreased dermal and pulmonary fibrosis and alleviated pulmonary hypertension via ICOS/CD28 blockade. Synonyms: ALPN-101; ALPN 101; ALPN101. Grade: 98% by HPLC. CAS No. 2270247-50-0.
ACBC
ACBC has been found to be a NMDA receptor partial agonist and could probably affect the signal transmission in the CNS. Synonyms: 1-Aminocyclobutane-1-carboxylic acid. Grade: ≥98% by HPLC. CAS No. 22264-50-2. Molecular formula: C5H9NO2. Mole weight: 115.13.
ACBC
ACBC. Group: Biochemicals. Grades: Purified. CAS No. 22264-50-2. Pack Sizes: 25mg. US Biological Life Sciences.
Ac-beta-chloro-D-Ala-Ome. Synonyms: Ac-D-Ala(Cl)-Ome; Ac beta chloro D Ala Ome. CAS No. 327064-63-1. Molecular formula: C6H10ClNO3. Mole weight: 179.6.
ACBI1
ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375564-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128359.
ACBI2
ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7?nM), which selectively degrades SMARCA2 with a DC50 value of 1?nM in RKO cells. ACBI2 can be used in the research of lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2913161-19-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151623.
ACBI3
ACBI3 (compound 7), a chemical probe, is a PROTAC targeting KRAS. ACBI3 is composed of PROTAC target protein ligand pan-KRAS degrader 1 (HY-162960) (red part), E3 ligase ligand E3 ligase Ligand 43 (HY-401613) (blue part) and PROTAC Linker 1-Bromo-4-(ethynyloxy)butane (HY-169992) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is E3 Ligase Ligand-linker Conjugate 143 (HY-169995). ACBI3 achieves in vivo degradation of oncogenic KRAS, resulting in durable pathway modulation and tumor regressions in KRAS mutant xenograft mouse models[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2938169-76-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157228.
ACBI3
ACBI3 is a pan-KRAS inhibitor. Synonyms: GLXC-27998. CAS No. 2938169-76-5. Molecular formula: C50H62N14O6S2. Mole weight: 1019.25.
ACBI-4
ACBI-4 is a selective GTP-loaded active state of KRAS (KRAS(on)) PROTAC degrader, with Kd values of 141 nM against KRASG12R. ACBI-4 forms a stable ternary complex with VHL, triggering ubiquitination and KRAS degradation via the ubiquitin-proteasome system. ACBI-4 induces antiproliferative effects in KRAS mutant-driven cancer cells. ACBI-4 can be used for the research of KRAS mutant-driven cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097985-19-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-176792.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about >80% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. TGC↑GCA ACG↓CGT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 16. Pack: 10 mM Tris-HCl (pH 7.5); 200 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1003EN.
Acc36 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 100U; 500U. ACCTGC(N)4↑ TGGACG(N)8&darr. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 36. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: RE-1004EN.
Acc65 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA(dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑GTACC CCATG↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus 65. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1005EN.
AccB1 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500U; 2500U. G↑GYRCC CCRYG↓G. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer K, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus B1. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1006EN.
AccB7 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. CCANNNN↑NTGG GGTN↓NNNNACC. Appearance: 10 X SE-buffer G. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus B7. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1007EN.
AccBS I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of dna fragments can be ligated. of these 50% can be recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GAG↑CGG CTC↓GCC. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Acinetobacter calcoaceticus BS. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1008EN.
Ac-c-Pro-Pro-Lys-Asp-NH2 is a selective human melanocortin 5 receptor (hMC5R) antagonist with an IC50 of 10 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 596135-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4665.
Ac-CoA Synthase-IN-1
Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM[1]. Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 508186-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104032.
Ac-CoA Synthase Inhibitor 1
Ac-CoA Synthase Inhibitor 1 is an anti-virus agent. Synonyms: 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea. Grade: ≥95%. CAS No. 508186-14-9. Molecular formula: C20H18N4O2S2. Mole weight: 410.51.
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor)
ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). ACSS2 inhibitor also inhibits the respiratory syncytial virus (RSV). Group: Inhibitors. Alternative Names: Ac-CoA Synthase Inhibitor1. CAS No. 508186-14-9. Pack Sizes: 5mg. Product ID: S8588. Formula: C20H18N4O2S2. Smiles: COCCNC(=O)NC1=CC2=C(C=C1)N=C(C(=N2)C3=CC=CS3)C4=CC=CS4. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Ac-Cys(Farnesyl)-OH
Ac-Cys(Farnesyl)-OH. CAS No: 135304-07-3
Sarchem Laboratories New Jersey NJ
Ac-D-a-indanylglycine
Ac-D-a-indanylglycine. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Ac-D-Arg(1)-ICA is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: Ac-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.
Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2
Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 819048-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4764.
Ac-dC-Me Phosphonamidite, an esteemed chemical compound employed in the biochemical industry, enables the modification and synthesis of DNA, augmenting its utility. Its prominent utility is distinguished by the introduction of the methyl group, targeting the 5th position within the cytosine base of DNA, ultimately giving rise to a diverse spectrum of gene expression alterations and therapeutic benefits, which hold substantial potential in the field of disease management, particularly in cancer. Synonyms: 5'-Dimethoxytrityl-N4-acetyl-2'-deoxyCytidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite; N-Acetyl-3'-O-[methyl(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. Molecular formula: C39H49N4O7P. Mole weight: 716.81.
Ac-dC-Me Phosphoramidite
AC-dC-Me Phosphoramidite is an indispensable instrument within the realm of biomedical research, finding its purpose in the intricate art of DNA strand modification and enhancement. Synonyms: dC(Ac)-3'-Methoxy Phosphoramidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite; DNA C(Ac) OMe-amidite; 2'-Deoxycytidine-(N-Ac)-3'-Methyl-Phosphoramidite. Grade: ≥95%. CAS No. 833480-37-8. Molecular formula: C39H49N4O8P. Mole weight: 732.81.
Ac-dC-PACE Phosphoramidite
Ac-dC-PACE Phosphoramidite, a vital instrument in the construction of oligonucleotides for eradicating viral infections and cancer, operates as a foundation for modified nucleic acid analogs, which specialize in pinpointing particular RNA or DNA sequences within the body. With its distinctive chemical makeup, it has the ability to stifle the spread of viruses and impede the progression of tumors, rendering it an auspicious nomination within the realm of biomedicine. Synonyms: DNA C(Ac) PACE amidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; dC(Ac)-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-[(bisisopropylamino)(2-cyano-1,1-dimethylethoxycarbonylmethyl)phosphino]-2'-deoxycytidine. Grade: ≥95%. CAS No. 411234-22-5. Molecular formula: C45H56N5O9P. Mole weight: 841.93.
Ac-DEVD-AFC
Ac-DEVD-AFC is a fluorogenic substrate (λex=400 nm, λem=530 nm). Uses: Scientific research. Category: Signaling pathways. CAS No. 201608-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1005.
Ac-DEVD-AFC
Ac-DEVD-AFC is a fluorogenic substrate for caspase-3 and related caspases. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Synonyms: Ac-DEVD-7-amido-4-trifluoroMethylcoumarin; Caspase-3 Substrate ?, Fluorogenic; Ac-Asp-Glu-Val-Asp-AFC; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine. Grade: ≥90%. CAS No. 201608-14-2. Molecular formula: C30H34F3N5O13. Mole weight: 729.61.
Ac-DEVD-AMC
Ac-DEVD-AMC is a fluorogenic substrate for caspase-3. Caspase activity can be quantified by fluorescent detection of free AMC (7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Synonyms: N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin; N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine. Grade: ≥95%. CAS No. 169332-61-0. Molecular formula: C30H37N5O13. Mole weight: 675.64.
Ac-DEVD-AMC
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 169332-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1003.
Ac-DEVD-CHO
Ac-DEVD-CHO is a Caspase-3 inhibitor with a Ki value of 230 pM. Uses: Scientific research. Category: Signaling pathways. CAS No. 169332-60-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1001.
Ac-DEVD-CHO
Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Group: Inhibitors. Alternative Names: Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO. CAS No. 169332-60-9. Pack Sizes: 2mg. Product ID: S7901. Formula: C20H30N4O11. Smiles: CC(C)C(C(=O)NC(CC(=O)O)C=O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Ac-DEVD-CHO
Ac-DEVD-CHO is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. Uses: Cysteine proteinase inhibitors. Synonyms: N-acetyl-asp-glu-val-asp-al; Ac-Asp-Glu-Val-Asp-Aldehyde; L-Valinamide,N-acetyl-L-a-aspartyl-L-a-glutamyl-N-(2-carboxy-1-formylethyl)-. Grade: 95 %. CAS No. 169332-60-9. Molecular formula: C20H30N4O11. Mole weight: 502.47.
Ac-DEVD-CHO acetate
Ac-DEVD-CHO acetate is a specific inhibitor of Caspase-3. Synonyms: Caspase-3 Inhibitor I; N-acetyl-asp-glu-val-asp-al acetate; Ac-Asp-Glu-Val-Asp-al acetate; Ac-DEVD-al.CH3CO2H; L 761191 acetate; MF 191 acetate; N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-L-aspart-1-al acetate; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide acetate. Grade: ≥95%. Molecular formula: C22H34N4O13. Mole weight: 562.52.
Ac-DEVD-CMK
Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Synonyms: Ac-Asp-Glu-Val-Asp-chloromethylketone; Caspase-3 Inhibitor III; N-acetyl-Asp-Glu-Val-Asp-chloromethylketone; N-Acetyl-L-α-aspartyl-L-α-glutamyl-N-[(2S)-1-carboxy-4-chloro-3-oxo-2-butanyl]-L-valinamide; (2S,5S,8S,11S)-8-(2-carboxyethyl)-11-(carboxymethyl)-2-(2-chloroacetyl)-5-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazatetradecane-1-carboxylic acid. Grade: ≥98%. CAS No. 285570-60-7. Molecular formula: C21H31ClN4O11. Mole weight: 550.95.
Ac-DEVD-CMK
Ac-DEVD-CMK (Caspase-3 Inhibitor III) is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK significantly inhibits apoptosis induced by high levels of glucose or Ingenol 3,20-dibenzoate?(HY-137295). Ac-DEVD-CMK can be used in a variety of experimental approaches to inhibit apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Caspase-3 Inhibitor III. CAS No. 285570-60-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0034.
Ac-DEVD-pNA
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) (Km=9.7μM) and related cysteine proteases. Synonyms: Ac-DL-Asp-DL-Glu-DL-Val-DL-Asp-pNA; DEVD; 4-[(2-acetamido-3-carboxypropanoyl)amino]-5-[[1-[[3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid; NAc-Asp-Glu-Val-Asp-pNA. CAS No. 189950-66-1. Molecular formula: C26H34N6O13. Mole weight: 638.58.
Ac-DEVD-pNA
Ac-DEVD-pNA is a ligand for caspase-3/-7 and related cysteine proteases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 189950-66-1. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1006.
Acetylleucine is a drug mianly used to treat the vertigo.It has been listed. Uses: Acetylleucine is used to treat the vertigo. Synonyms: Acetylleucine; N-Acetyl-DL-leucine; DL-Leucine,N-acetyl-; Acetyl-DL-leucine; Tanganil; 2-Acetamido-4-methylpentanoic acid. Grade: >98 %. CAS No. 99-15-0. Molecular formula: C8H15NO3. Mole weight: 173.21.
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). It is selective for caspase-3 over caspase-1 and caspase-8 (IC50s = 148 and 1,100 nM, respectively). Ac-DMQD-CHO inhibits apoptosis induced by camptothecin in immortalized human T/C 28a4 chondrocytes and primary human chondrocytes. In vivo, Ac-DMQD-CHO (1 mg/kg, i.v.) reduces the number of apoptotic cells, cavitation, and demyelination in a rat model of traumatic injury to the spinal cord. Synonyms: Ac-Asp-Met-Gln-Asp-CHO; Caspase-3 Inhibitor. Grade: ≥95%. Molecular formula: C20H31N5O10S·xCF3COOH. Mole weight: 533.6.
Ac-DNLD-CHO
Ac-DNLD-CHO is a Caspase-3/7 inhibitor with IC50 of 3.2 nM and 22.6 nM, respectively. Ac-DNLD-CHO may be an attractive lead compound to generate novel effective non-peptidic pharmaceuticals for caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases. Synonyms: N-acetyl-Asp-Asn-Leu-Asp-aldehyde; Ac-Asp-Asn-Leu-Asp-al; Caspase-3/7 Inhibitor II. CAS No. 775289-20-8. Molecular formula: C20H31N5O10. Mole weight: 501.49.
Ac-D-phenylglycinol 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
ACDPP hydrochloride
ACDPP hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 37804-11-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ACDPP hydrochloride
The hydrochloride salt form of ACDPP, which has been found to be a mGluR-5 antagonist. Synonyms: 3-Amino-6-chloro-5-dimethylamino-N-2-pyridinylpyrazinecarboxamide hydrochloride. Grade: ≥99% by HPLC. CAS No. 37804-11-8. Molecular formula: C12H13ClN6O.HCl. Mole weight: 329.19.
Ac-DQTD-CHO
Ac-DQTD-CHO is an inhibitor of caspase-3 (Ki = 1.27 nM), caspase-8 (Ki = 9.75 nM), caspase-9 (Ki = 14.5 nM) and caspase-7 (Ki = 21.8 nM). Synonyms: Ac-Asp-Gln-Thr-Asp-al; N-acetyl-Asp-Gln-Thr-Asp-aldehyde; N-Acetyl-L-α-aspartyl-L-glutaminyl-N-[(1S)-2-carboxy-1-formylethyl]-L-threoninamide. CAS No. 958001-91-7. Molecular formula: C19H29N5O11. Mole weight: 503.46.
Ac-DQTD-MCA
Ac-DQTD-MCA is a synthetic peptide substrate for Caspase-7/3. Ac-DQTD-MCA has been used as a tool for the study of protein interactions. Synonyms: Ac-Asp-Gln-Thr-Asp-AMC; Ac-Asp-Gln-Thr-Asp-MCA; Acetyl-L-aspartyl-L-glutaminyl-L-threonyl-L-aspartic acid α-(4-methyl-coumaryl-7-amide). Molecular formula: C29H36N6O13. Mole weight: 676.63.
ACEA
ACEA is a selective cannabinoid receptor 1 (CB1R) agonist (Ki = 1.4 nM) with much higher affinity over CB2R. CB1 receptors are mainly expressed in the central and peripheral nervous system. Synonyms: N-(2-chloroethyl)icosa-5,8,11,14-tetraenamide; 5,8,11,14-Eicosatetraenamide,N-(2-chloroethyl)-, (5Z,8Z,11Z,14Z); (5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)-5,8,11,14-eicosatetraenamide; Arachidonyl-2'-chloroethylamide. CAS No. 220556-69-4. Molecular formula: C22H36ClNO. Mole weight: 365.986.
ACEA
ACEA (short for arachidonyl-2'-chloroacetamide) is a synthetic organic compound that acts as an agonist of the cannabinoid receptor CB1. It is a chemical that affects the endocannabinoid system in the body, which regulates various physiological processes such as appetite, pain perception, mood, and memory[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Arachidonyl-2-chloroethylamide. CAS No. 220556-69-4. Pack Sizes: 5 mg (68.31 mM * 200 μL in Methyl acetate); 10 mg (68.31 mM * 400 μL in Methyl acetate); 25 mg (68.31 mM * 1 mL in Methyl acetate); 50 mg (68.31 mM * 2 mL in Methyl acetate). Product ID: HY-110004.
Acebilustat
Acebilustat, formerly known as ZK322, is an oral anti-inflammatory designed to reduce the production of leukotriene B4 (LTB4). Synonyms: 4-(((1S,4S)-5-(4-(4-(oxazol-2-yl)phenoxy)benzyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)methyl)benzoic acid; ZK322; ZK-322; ZK 322; CTX-4430; EP-501; CTX4430; EP501; CTX 4430; EP 501; Acebilustat, CAS#943764-99-6. CAS No. 943764-99-6. Molecular formula: C29H27N3O4. Mole weight: 481.55.
Acebrophylline
Acebrophylline can be utilized for adverse effect, pharmacological activity and biological study of effect of acebrophylline vs. sustained release theophylline in patients of chronic obstructive pulmonary disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 96989-76-3. Pack Sizes: 25mg, 100mg. Molecular Formula: C13H18Br2N2O C9H10N4O4, Molecular Weight: 616.299999999999. US Biological Life Sciences.