A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Alrizomadlin is a highly potent and chemically stable E3 ubiquitin-protein ligase Mdm2 (Hdm2) inhibitor. It is used in the treatment and prevention of osteoarthritis. Synonyms: APG-115; AA-115; 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid; APG115; APG 115; NSC831270. Grade: >98%. CAS No. 1818393-16-6. Molecular formula: C34H38Cl2FN3O4. Mole weight: 642.59.
Alrizomadlin
Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APG-115; AA-115. CAS No. 1818393-16-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101518.
ALS-8112
ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1445379-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12983.
ALS-8176 (active form)
ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneALS-8176 (active form); ALS-8112; ALS8112; ALS 8112.UNII-7795987MKM7795987MKMCHEMBL3417243SCHEMBL15070479CS-5472; HY-12983; CS 5472; HY 12983; CS5472; HY129834'-Chloromethyl-2'-deoxy-2'-fluorocytidineCytidine. Grade: 99.67%. CAS No. 1445379-92-9. Molecular formula: C10H13ClFN3O4. Mole weight: 293.68.
Alsevalimab
Alsevalimab is a human monoclonal antibody that targets B7-H4 with potential antineoplastic and immune checkpoint inhibitory activities. CAS No. 2254029-91-7.
Alsevalimab
Alsevalimab is a humanized, afucosylated IgG1 monoclonal antibody against B7-H4. Alsevalimab blocks the binding of the B7-H4 protein to the receptors on the surface of T cells, reversing the immunosuppressive state in the tumor microenvironment, thereby activating the killing effect of T cells on cancer cells. Alsevalimab can be used in combination with Pembrolizumab (HY-P9902), and shows good safety profiles[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2254029-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99242.
ALS-I
ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 308818-13-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg. Product ID: HY-44157.
AlSi10Mg Aluminum Alloy Powder
AlSi10Mg Aluminum Alloy Powder.
Al-Si Alloy Powder
Al-Si Alloy Powder. Purity: 99.9%+.
Also Nameel F46 Tubing
Also Nameel F46 Tubing.
Alsterpaullone
Alsterpaullone (9-Nitropaullone) is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders[1]. Alsterpaullone induces apoptosis in leukemia cell line[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 9-Nitropaullone; NSC 705701. CAS No. 237430-03-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108359.
Alsterpaullone
Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grade: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3.
Alsterpaullone
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 237430-03-4. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H11N3O3. US Biological Life Sciences.
Worldwide
Alstolenine
Alstolenine is an alkaloid compound found in the Alstonia venenata. Synonyms: Deacetylakuammiline trimethylgallate. Grade: >95%. CAS No. 85769-33-1. Molecular formula: C31H34N2O7. Mole weight: 546.6.
Alstonic acid A
Alstonic acid A can be found in the herbs of Alstonia scholaris. Synonyms: (3alpha,4beta)-3-(1,1-Dimethyl-2-oxoethyl)-4,8,9,20-tetramethyl-19-norpregn-5(10)-ene-4-acetic acid. Grade: >98%. CAS No. 1159579-44-8. Molecular formula: C30H48O3. Mole weight: 456.7.
Alstonic acid B
Alstonic acid B is a natural compound isolated from the herbs of Alstonia scholaris. Synonyms: Alstonic acid B; 1159579-45-9; 2-[(1R,4S,5R,8R,9R,12S,16R,19S)-4,9,12,17,17,19-hexamethyl-18-oxo-8-propan-2-yl-19-pentacyclo[14.2.1.01,13.04,12.05,9]nonadec-13-enyl]acetic acid; ZINC96023603; AKOS032962124. Grade: 98.0%. CAS No. 1159579-45-9. Molecular formula: C30H46O3. Mole weight: 454.695.
Alstonic Acid B
Alstonic Acid B. CAS No. 1159579-45-9. Purity: 98%. Product ID: ACM1159579459. Molecular formula: C30H46O3. Mole weight: 454.7. IUPAC Name: 2-[(1R,4S,5R,8R,9R,12S,16R,19S)-4,9,12,17,17,19-hexamethyl-18-oxo-8-propan-2-yl-19-pentacyclo[14.2.1.01,13.04,12.05,9]nonadec-13-enyl]acetic acid. Alfa Chemistry - ISO 9001:32057 Certified.
ALT-007
ALT-007 is an orally active serine palmitoyltransferase (SPT) inhibitor that selectively reduces the levels of toxic very-long-chain deoxysphingolipids to enhance protein homeostasis. ALT-007 restores aging-related loss of muscle mass in a mouse model of sarcopenia. ALT-007 enhances protein homeostasis in both mouse and C. elegans models of aging and disease. ALT-007 can be used for age-related neuromuscular diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2035010-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-170794.
Altanserin
Altanserin can synthesize Fluorine-18 Altanserin. Fluorine-18 Altanserin binds to the brain 5HT2 receptors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76330-71-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119156.
Altanserin hydrochloride
Altanserin hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135280-78-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Altanserin hydrochloride
Altanserin hydrochloride is the hydrochloride salt of altanserin, which is a selective and potent 5-HT2A receptor antagonist with Ki value of 0.13 nM. It is centrally active following systemic administration in vivo. It is also a useful intermediate for organic synthesis. Synonyms: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride. Grade: ≥98% by HPLC. CAS No. 1135280-78-2. Molecular formula: C22H23FN3O2SCl. Mole weight: 447.95.
Alta oils smoke tree (sumac) essential oil
Alta oils smoke tree (sumac) essential oil. Alternative Names: Cotinus Coggygria Branch/Leaf Oil. CAS No. 89997-96-6. Purity: 100% Pure and Natural. Product ID: FFC-AR-89997966. Alfa Chemistry - ISO 9001:32057 Certified.
Altechromone A
Altechromone A is produced from Alternaria brassicicola ML-P08. Altechromone A shows antimicrobial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively. Synonyms: 7-Hydroxy-2,5-dimethylchromone; 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one. Grade: 98.0%. CAS No. 38412-47-4. Molecular formula: C11H10O3. Mole weight: 190.19.
Alteichin
It is produced by the strain of Alternaria eichorniae. Phytotoxic substances. Synonyms: alterperylenol; Alteichin; GRK18WHV7F; C10295; (+)-Alterperylenol; AC1L2PAW; Alterperylnol; CHEBI:2614; DTXSID10237401; ZINC4098645; AKOS030213167; (1S,12aR,12bS)-1,4,9,12a-tetrahydroxy-2,12b-dihydro-1H-perylene-3,10-dione; Q27105736; 3,10-Perylenedione,1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1S,12aR,12bS)-; 3,10-Perylenedione, 1,2,12a,12b-tetrahydro-1,4,9,12a-tetrahydroxy-, (1alpha,12abeta,12balpha)-(+)-. Grade: 95%. CAS No. 88899-62-1. Molecular formula: C20H14O6. Mole weight: 350.32.
Altemicidin
It is produced by the strain of Streptomyces sioyaensis. It has acaricidal and anti-tumor activity. The inhibition IC50 of L1210 and IMC cancer cells was 0.84 and 0.82 ?/mL. Synonyms: CTK4B4358; DTXSID20925120; 1H-Cyclopenta[c]pyridine-7-carboxylicacid,4-(aminocarbonyl)-7-[[2-(aminosulfonyl)acetyl]amino]-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-,(4aR,6S,7R,7aS)-; LS-136376; Q15410226; 6-Hydroxy-7-({[(1-hydroxy-2-sulfamoylethylidene)amino]oxy}carbonyl)-2-methyl-2,4a,5,6,7,7a-hexahydro-1H-cyclopenta[c]pyridine-4-carboximidic acid. Grade: 99%. CAS No. 125399-82-8. Molecular formula: C13H20N4O7S. Mole weight: 376.38.
Alteminostat
Alteminostat is a histone deacetylase inhibitor and antineoplastic drug candidate. Alteminostat inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. Uses: Histone deacetylase inhibitors. Synonyms: 1-Piperazinecarboxamide, N-(7-(hydroxyamino)-7-oxoheptyl)-4-methyl-N-(4-(1-methyl-1H-indazol-6-yl)phenyl)-; CKD-581. CAS No. 1246374-97-9. Molecular formula: C27H36N6O3. Mole weight: 492.61.
Altenuene
(-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. It has antioxidant activity and inhibits cholinesterases. Synonyms: (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one. Grade: >95%. CAS No. 29752-43-0. Molecular formula: C15H16O6. Mole weight: 292.29.
Altenuene
Altenuene is a heptaketide isolated from an endolichenic fungal strain Nigrospora sphaerica[1]. Uses: Scientific research. Category: Natural products. CAS No. 29752-43-0. Pack Sizes: 1 mg. Product ID: HY-N6713A.
Altenusin
Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grade: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27.
Altenusin, Penicillium sp.
Sphingomyelinase (N-SMase) and strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain kinase inhibitor. Also exhibits anti-HIV-1 integrase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 31186-12-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
Alteplase
Alteplase (Actilyse; Activase), a tissue plasminogen activator prepared by recombination, is a thrombolytic agent that play important roles in acute ischemic stroke, pulmonary embolism, acute myocardial infarction, and occluded catheters[1][2][3][4].The product size below only indicate the effective content of Alteplase. The ratio of Alteplase effective content : total content = 1:46-1:50. The actual ratio depends on the batch.). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Actilyse; Activase. CAS No. 105857-23-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108865.
Alterlactone
Alterlactone is produced from the endolichenic fungus Ulocladium sp. Alterlactone shows strong radical scavenging activity. Synonyms: 4,9,10-trihydroxy-2-methoxydibenzo[c,e]oxepin-5(7H)-one. Grade: 97.5%. CAS No. 1030376-89-6. Molecular formula: C15H12O6. Mole weight: 288.25.
alternansucrase
The product, which has quite different properties from other dextrans, has been called alternan. Group: Enzymes. Synonyms: sucrose-1,6(3)-α-glucan 6(3)-α-glucosyltransferase; sucrose:1,6-, 1,3-α-D-glucan 3-α- and 6-α-D-glucosyltransferase;sucrose:1,6(1,3)-α-D-glucan 6(3)-α-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.140. CAS No. 100630-46-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2366; alternansucrase; EC 2.4.1.140; 100630-46-4; sucrose-1,6(3)-α-glucan 6(3)-α-glucosyltransferase; sucrose:1,6-, 1,3-α-D-glucan 3-α- and 6-α-D-glucosyltransferase;sucrose:1,6(1,3)-α-D-glucan 6(3)-α-D-glucosyltransferase. Cat No: EXWM-2366.
Alternapyrone
Alternapyrone is a polyketide produced in A. oryzae heterologously expressing the A. solani-derived polyketide synthase gene alt5. CAS No. 676340-02-6. Molecular formula: C28H44O3. Mole weight: 428.65.
Alternapyrone B
Alternapyrone B is an extraordinary and innovative biomedical compound, used for studying fungal ailments, notably candidiasand aspergillosis. CAS No. 2254311-61-8. Molecular formula: C28H42O5. Mole weight: 458.63.
Alternaric acid
It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Synonyms: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grade: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46.
Alternariol
An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Alternative Names: 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; NSC 638263. Grades: Highly Purified. CAS No. 641-38-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Alternariol
It is produced by the strain of Alternaria tenuis. The inhibition concentration of S. aureus and E. coli was 1:40000 and 1:20000, respectively. Synonyms: 3,7,9-Trihydroxy-1-methyl-6H-benzo[c]chromen-6-one; 3,7,9-trihydroxy-1-methylbenzo[c]chromen-6-one; 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; CCRIS 6734; AOH; KN9L4260JW; CHEBI:64983; NSC638263; 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone; 3,7,9-Trihydroxy-1-methyl-6H-dibenzo(b,d)pyran-6-one; CHEMBL519982. Grade: 97%. CAS No. 641-38-3. Molecular formula: C14H10O5. Mole weight: 258.23.
Alternariol
Alternariol is an orally ingested mycotoxin produced by Alternaria, capable of inhibiting the activity of topoisomerase I and II (topoisomerase I, topoisomerase II). Alternariol has weak estrogenic (Estrogen Receptor/ERR) and androgen/antiandrogen (Androgen Receptor) effects. Alternariol can induce apoptosis, trigger cell cycle arrest, suppress innate immune responses, and exhibit anti-tumor activity. Alternariol has genotoxic, mutagenic, and endocrine-disrupting effects[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 641-38-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-N6714.
Alternariol 9-methyl ether
Alternariol monomethyl ether is produced from the media of Alternaria alternata strain 261. Alternariol monomethyl ether, an Alternaria toxin, is a strong mutagen in Escherichia coli strain ND-160. Alternariol monomethyl ether possesses cytotoxic and immunosuppressive properties. It has genotoxic properties and can cause oxidative DNA damage. Synonyms: 2-Biphenylcarboxylic acid, 2',3,4'-trihydroxy-5-methoxy-6'-methyl-, δ-lactone; 6H-Dibenzo[b,d]pyran-6-one, 3,7-dihydroxy-9-methoxy-1-methyl-; 3,7-Dihydroxy-9-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol 4-O-methyl ether; Alternariol 9-O-methyl ether; Alternariol monomethyl ether; Alternariol-5-O-methyl ether; AME; Djalonensone; NSC 638262. Grade: 98%. CAS No. 23452-05-3. Molecular formula: C15H12O5. Mole weight: 272.25.
Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt
Alternariol 9-Methyl Ether 3-Sulfate Ammonium Salt is a derivative of Alternariol 9-Methyl Ether (A575770) which is an alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Grades: Highly Purified. CAS No. 1488351-25-2. Pack Sizes: 1mg. Molecular Formula: C15H12O8S(NH3), Molecular Weight: 352.321703. US Biological Life Sciences.
Worldwide
Alternariol 9-Monomethyl Ether
Alternariol Monomethyl Ether is a mycotoxins found in subsistence farmed maize. Also, it is a natural mycotoxin isolated from the fermentation broth of Trichoderma sp. Jing-8 with phytotoxic, antibacterial and antioxidant activities. Also, it is derived from 3,5-Dimethoxyiodobenzene (D460640), which is an intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Group: Biochemicals. Grades: Highly Purified. CAS No. 23452-05-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H12O5, Molecular Weight: 272.25. US Biological Life Sciences.
Worldwide
Alternariol-[d3]
Alternariol-[d3] is a deuterated version of Alternariol. Alternariol is produced by the strain of Alternaria tenuis. The inhibition concentration of S. aureus and E. coli was 1:40000 and 1:20000, respectively. Molecular formula: C14H7D3O5. Mole weight: 261.24.
Alternariol monomethyl ether
The 50 ppm acetonitrile solution of Alternariol monomethyl ether, shows activities as a cholinesterase inhibitor as well as an anti-fungal agent, could be commonly used as a standard solution. It is an alternaria mycotoxin and genotoxin, which can inhibit the activity of DNA-topoisomerases. Synonyms: 6H-Dibenzo[b,d]pyran-6-one, 3,7(3,9 or 7,9)-dihydroxy-9(7 or 3)-methoxy-1-methyl-; 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one; Alternariol, methyl ether. Grade: >95%. CAS No. 26894-49-5. Molecular formula: C15H12O5. Mole weight: 272.25.
Alternariol Monomethyl Ether
An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks. Group: Biochemicals. Alternative Names: 3,7(3,9 or 7,9)-Dihydroxy-9(7 or 3)-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one. Grades: Highly Purified. CAS No. 26894-49-5. Pack Sizes: 1mg. US Biological Life Sciences.
Mycotoxin. Antifungal. Phytotoxic. Shown to possess DNA strand-breaking activity. Inhibits the activity of topoisomerase IIalpha (Topo IIalpha) in mammalian cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 26894-49-5. Pack Sizes: 500ug, 1mg, 5mg. US Biological Life Sciences.
Worldwide
alternative-complement-pathway C3/C5 convertase
A bimolecular complex of complement fragment Bb with either C3b or cobra venom factor; Bb contains the active site. Bb is formed by cleavage of proenzyme factor B by factor D. Cleavage of complement component C5 requires additional C3b which binds C5 and renders it susceptible to cleavage by C3b,Bb complex. C3b,Bb is stabilized in plasma by factor P. Complement factor B is in peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: complement component C3/C5 convertase (alternative); proenzyme factor B; properdin factor B; C3 proactivator; glycine-rich β-glycoprotein; heat-labile factor; C3 convertase; C3. Enzyme Commission Number: EC 3.4.21.47. CAS No. 80295-67-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4140; alternative-complement-pathway C3/C5 convertase; EC 3.4.21.47; 80295-67-6; complement component C3/C5 convertase (alternative); proenzyme factor B; properdin factor B; C3 proactivator; glycine-rich β-glycoprotein; heat-labile factor; C3 convertase; C3b,Bb,CVF,Bb,C5 convertase; (C3b)n,Bb; complement C 3(C 5) convertase (amplification); alternative complement pathway C3(C5) convertase; C5 convertase; CVF,Bb; (CVF)-dependent glycine-rich-β-glucoprotein; cobra venom factor-dependent C3 convertase. Cat No: EXWM-4140.
Altertoxin I
Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1]. Uses: Scientific research. Category: Natural products. Alternative Names: Dihydroalterperylenol. CAS No. 56258-32-3. Pack Sizes: 1 mg. Product ID: HY-N6724.
Altertoxin I
Altertoxin I, a sort of natural mycotoxin, could be obtained from Alternaria fungi and has been found to restrain human topoisomerase II as well as bacterial gyrase. Altertoxin I (and other altertoxins) inhibit the HIV replication. Synonyms: Altertoxin-I; BC9625200. Grade: ≥97%. CAS No. 56258-32-3. Molecular formula: C20H16O6. Mole weight: 352.34.
Althaea rosea flower extract
Althaea rosea flower extract. Alternative Names: althaea rosea extract. CAS No. 90045-76-4. Product ID: FFC-AR-90045764. Alfa Chemistry - ISO 9001:32057 Certified.
Althiazide
Diuretic and antihypertensive. Group: Biochemicals. Alternative Names: 6-Chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; 3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide; Althizide; Altizid; Altizide. Grades: Highly Purified. CAS No. 5588-16-9. Pack Sizes: 10mg. US Biological Life Sciences.
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Althiomycin
It is produced by the strain of Streptomyces althiotious. Anti-Gram-positive bacteria (weak) and E. coli (weak). Synonyms: Althiomycin; Altiomycin; NSC 102809; 4-Thiazolecarboxamide, N-(1-(4-((2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl)-4,5-dihydro-2-thiazolyl)-2-hydroxyethyl)-2-((hydroxyimino)methyl)-; NSC102809. CAS No. 12656-40-5. Molecular formula: C16H17N5O6S2. Mole weight: 439.47.
Altiloxin A
It is produced by the strain of Phoma asparagi Sacc ALD-8. It is a plant toxin that can inhibit the growth of roots. Synonyms: (1as,3s,4r,4ar,8ar)-3-hydroxy-3,4a,8,8-tetramethyloctahydro-1ah-naphtho[1,8a-b]oxirene-4-carboxylic acid; (-)-Altiloxin A; CTK5H1580; DTXSID20896902; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS,3R,4R,4aR,8aR)-; 3H-Naphth(1,8a-b)oxirene-4-carboxylic acid, octahydro-3-hydroxy-3,4a,8,8-tetramethyl-, (1aS-(1aalpha,3beta,4alpha,4aalpha,8aS*))-. Grade: 95%. CAS No. 92675-11-1. Molecular formula: C15H24O4. Mole weight: 268.35.
Altiloxin B
It is produced by the strain of Phoma asparagi Sacc ALD-8. Plant toxin. Synonyms: (1aS,8aS)-7α-Chlorooctahydro-3β-hydroxy-3,4aα,8,8-tetramethyl-3H-naphth[1,8a-b]oxirene-4α-carboxylic acid. CAS No. 92675-14-4. Molecular formula: C15H23O4Cl. Mole weight: 302.79.
Altiratinib
Altiratinib (DCC-2701) is a multi-targeted kinase inhibitor with IC50s of 2.7, 8, 9.2, 9.3, 0.85, 4.6, 0.83 nM for MET, TIE2, VEGFR2, FLT3, Trk1, Trk2, and Trk3 respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DCC-2701. CAS No. 1345847-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0791.
Altiratinib
Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF. DCC-2701 may be superior to HGF antagonists that are in clinical trials and that pTyr(1349) levels might be a good indicator of c-MET activation and likely response to targeted therapy as a result of signals from the microenvironment. Synonyms: DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164; Altiratinib. Grade: >98%. CAS No. 1345847-93-9. Molecular formula: C26H21F3N4O4. Mole weight: 510.46.
Altiratinib
Altiratinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 1345847-93-9. Pack Sizes: 100mg. US Biological Life Sciences.
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AlTiVFeCr High-Entropy Alloy
Unlike most current alloy materials, high-entropy alloys are alloy materials that contain equimolar or approximately equimolar elements. AlTiVFeCr High-Entropy Alloy is composed of Al, Ti, V, and Fe.
Altizide EP Impurity B
An impurity of a thiazide diuretic Altizide. Synonyms: 3-((2,2-Dimethoxyethyl)thio)propene; 3-[(2,2-dimethoxyethyl)thio]propene. Grade: 95%. CAS No. 84522-35-0. Molecular formula: C7H14O2S. Mole weight: 162.25.
Altogen Labs Biology CRO
Altogen Labs is a preclinical contract research organization (CRO) that provides a wide range of laboratory services to biotech and pharma companies. Services includes: Xenograft models (CDX and PDX), pharm/tox studies, PK/PD, and more. Uses: Preclinical research services: Validated xenograft models (CDX and PDX). Product ID: 9999.
Nevada, Texas, USA
Altrenogest
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone. It is a synthetic active progesterone. It can suppress the sow's estrus to achieve the purpose of estrus in the pig herd at the same time, reshape the sow's physiological cycle, and induce the sow to estrus at the same time. Uses: Progestins. Synonyms: Altrenogest; A 35957; A-35957; Allyl trenbolone; DRC 6246; R 2267; REGU-MATE; Regumate; RU 2267; RU-2267. Grade: >98%. CAS No. 850-52-2. Molecular formula: C21H26O2. Mole weight: 310.43.
Altrenogest
Altrenogest. Group: Biochemicals. Alternative Names: (17b)-17-Hydroxy-17-(2-propen-1-yl)estra-4,9,11-trien-3-one; (17b)-17-Hydroxy-17-(2-propenyl)estra-4,9,11-trien-3-one; 17a-Allyl-17-hydroxyestra-4,9,11-trien-3-one. Grades: Highly Purified. CAS No. 850-52-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C21H26O2. US Biological Life Sciences.
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Altrenogest
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone. It is a synthetic active progesterone. It can suppress the sow's estrus to achieve the purpose of estrus in the pig herd at the same time, reshape the sow's physiological cycle, and induce the sow to estrus at the same time. Category: Apis for progestogens. Synonyms: Allyltrenbolone. Regumate. Allyl trenbolone. CAS No. 850-52-2. Product ID: API850522. Molecular formula: C21H26O2. Mole weight: 310.4. EINECS: 212-703-1. SMILES: CC12C=CC3=C4CCC(=O)C=C4CCC3C1CCC2(CC=C)O.
Altrenogest 19,19,20,21,21 (d5)
Altrenogest 19,19,20,21,21-d5 is labelled Altrenogest (A575755) which is a synthetic progestational agent used in veterinary medicine for the control of estrus in mares. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250ug, 500ug. Molecular Formula: C21H21D5O2. US Biological Life Sciences.
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Altrenogest Impurity 10
Altrenogest Impurity 10. Uses: For analytical and research use. Molecular formula: C23H32O3. Mole weight: 356.51. Catalog: APB10172.
Altrenogest Impurity 9
Altrenogest Impurity 9. Uses: For analytical and research use. Molecular formula: C21H26O3. Mole weight: 326.44. Catalog: APB10170.
Altretamine
Altretamine is an alkylating antineoplastic agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ENT-50852; RB-1515; WR-95704. CAS No. 645-05-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0181.
Altretamine
Altretamine is an anti-neoplastic agent. Uses: An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. antineoplastic. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine. Grade: > 98 %. CAS No. 645-05-6. Molecular formula: C9H18N6. Mole weight: 210.28.
Altretamine
An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic. Group: Biochemicals. Alternative Names: N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 1,3,5-Tris(dimethylamino)-s-triazine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine; ENT 50852; HMM; Hemel; Hexalen; Hexamethylmelamine; Hexylen; NSC 13875. Grades: Highly Purified. CAS No. 645-05-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
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Altretamine hydrochloride
Altretamine hydrochloride, also called as hexamethylmelamine hydrochloride, is an alkylating agent with apparently less toxicity compared to other cytotoxic drugs used for palliation of patients with recurrent epithelial ovarian cancer. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine; hydrochloride Altretamine hydrochloride Altretamine (hydrochloride) 2975-00-0 Hexamethylmelamine HCl UNII-30FQ7QG6VM 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-, monohydroch. CAS No. 2975-00-0. Molecular formula: C9H19ClN6. Mole weight: 246.74.