A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Biotin-PEG5-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG5-amine can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG5-CH2CH2NH2. Grade: >95%. CAS No. 113072-75-6. Molecular formula: C22H42N4O7S. Mole weight: 506.66.
Biotin-PEG5-azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG5-azide can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG5-CH2CH2N3. Grade: >97%. CAS No. 1163732-89-5. Molecular formula: C22H40N6O7S. Mole weight: 532.65.
Biotin-PEG5-azide
Biotin-PEG5-azide. Uses: Designed for use in research and industrial production. Product Category: Biotin PEG Linkers. CAS No. 1309649-57-7. Molecular formula: C20H36N6O6S. Mole weight: 488.6. Purity: 95%+. Product ID: ACM1309649577. Alfa Chemistry ISO 9001:2015 Certified.
Biotin-PEG5-NH-Boc
Biotin-PEG5-NH-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG5-NH-Boc can be used in the synthesis of a series of PROTACs. CAS No. 189209-28-7. Molecular formula: C27H50N4O9S. Mole weight: 606.77.
Biotin-PEG5-thiol
Biotin-PEG5-thiol is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: Biotin-PEG5-SH. Grade: >95%. Molecular formula: C20H37N3O6S2. Mole weight: 479.21.
Biotin-PEG6-acid
(+)-Biotin-PEG6-acid (CAS# 1352814-10-8 ) is a useful research chemical. Synonyms: 3-[2-[2-[2-[2-[2-[2-[[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; 3-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid. Grade: >97%. CAS No. 1352814-10-8. Molecular formula: C25H45N3O10S. Mole weight: 579.70.
Biotin-PEG6-alcohol
Biotin-PEG6-alcohol is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-alcohol can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-OH; (+)-Biotin-PEG6-alcohol; Biotin-PEG6-OH. Grade: >97%. CAS No. 906099-89-6. Molecular formula: C22H41N3O8S. Mole weight: 507.64.
Biotin-PEG6-amine
Biotin-PEG6-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-amine can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-CH2CH2NH2; (+)-Biotin-PEG6-amine; Biotin-PEG6-CH2CH2NH2. Grade: >97%. Molecular formula: C24H46N4O8S. Mole weight: 550.71.
Biotin-PEG6-amine
Biotin-PEG6-amine. Uses: Designed for use in research and industrial production. Product Category: Biotin PEG Linkers. CAS No. 113072-75-6. Molecular formula: C22H42N4O7S. Mole weight: 506.66. Purity: 95%+. Product ID: ACM113072756. Alfa Chemistry ISO 9001:2015 Certified. Categories: Biotin PEG2 amine.
Biotin-PEG6-azide
Biotin-PEG6-azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-azide can be used in the synthesis of a series of PROTACs. CAS No. 1085938-09-5. Molecular formula: C24H44N6O8S. Mole weight: 576.71.
Biotin-PEG6-Boc
Biotin-PEG6-Boc is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Boc can be used in the synthesis of a series of PROTACs. CAS No. 1352814-07-3. Molecular formula: C29H53N3O10S. Mole weight: 635.81.
Biotin-PEG6-hydrazide
Biotin-PEG6-hydrazide is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG6-hydrazide. Grade: >95%. Molecular formula: C25H47N5SO9. Mole weight: 593.73.
Biotin-PEG6-NH-Boc
Biotin-PEG6-NH-Boc is a Biotin compound with a Boc protected amine moiety. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG6-NH-Boc; 1292268-20-2; HY-W190945; BP-23614; CS-0254648; tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate. Grade: 0.98. CAS No. 1292268-20-2. Molecular formula: C29H54N4O10S. Mole weight: 650.8.
Biotin-PEG6-NH-Mal
Biotin-PEG6-Mal is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Mal can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-NH-Mal; Biotin-PEG6-Mal; Biotin-PEG6-Maleimide; (+)-Biotin-PEG6-Maleimide. Grade: >97%. CAS No. 1808990-66-0. Molecular formula: C31H51N5O11S. Mole weight: 701.83.
Biotin-PEG6-NHS ester
Biotin-PEG6-NHS ester is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-NHS ester can be used in the synthesis of a series of PROTACs. Synonyms: (+)-Biotin-PEG6-NHS Ester. Grade: >97%. CAS No. 2055045-04-8. Molecular formula: C29H48N4O12S. Mole weight: 676.78.
Biotin-PEG6-Thalidomide
Biotin-PEG6-Thalidomide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG6-Thalidomide can be used in the synthesis of a series of PROTACs. CAS No. 2144775-48-2. Molecular formula: C37H53N5O12S. Mole weight: 791.91.
Biotin-PEG7-amine
Biotin-PEG7-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-amine can be used in the synthesis of a series of PROTACs. Synonyms: Biotin-PEG7-NH2. Grade: >95%. CAS No. 1334172-76-7. Molecular formula: C26H50N4O9S. Mole weight: 594.76.
Biotin-PEG7-amine
Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334172-76-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140898.
Biotin-PEG7-azide
Biotin-PEG7-azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-azide can be used in the synthesis of a series of PROTACs. CAS No. 1334172-75-6. Molecular formula: C26H48N6O9S. Mole weight: 620.76.
Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. Synonyms: Biotin-PEG7-C2-NH-Vidarabine-S-CH3|HY-145248|CS-0370383. Grade: >98%. Molecular formula: C37H62N8O12S2. Mole weight: 875.06.
Biotin-PEG7-C2-S-Vidarabine
Biotin-PEG7-C2-S-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruse. Synonyms: Biotin-PEG7-C2-S-Vidarabine|HY-145247|CS-0370381. Grade: >98%. Molecular formula: C36H60N8O12S2. Mole weight: 861.04.
Biotin-PEG7-thiourea
Biotin-PEG7-thiourea is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG7-thiourea can be used in the synthesis of a series of PROTACs. CAS No. 2353409-59-1. Molecular formula: C27H51N5O9S2. Mole weight: 653.85.
Biotin-PEG8-acid
Biotin-PEG8-acid is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG8-acid can be used in the synthesis of a series of PROTACs. CAS No. 2143964-62-7. Molecular formula: C29H53N3O12S. Mole weight: 667.81.
Biotin-PEG8-alcohol
Biotin-PEG8-alcohol is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-OH; (+)-Biotin-PEG8-alcohol; Biotin-PEG8-OH. Grade: >97%. Molecular formula: C26H49N3O10S. Mole weight: 595.75.
Biotin-PEG8-amine is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG8-amine can be used in the synthesis of a series of PROTACs. CAS No. 2183447-27-8. Molecular formula: C28H54N4O10S. Mole weight: 638.81.
Biotin-PEG8-amine
Biotin-PEG8-amine. Uses: Designed for use in research and industrial production. Product Category: Biotin PEG Linkers. CAS No. 1334172-76-7. Molecular formula: C26H50N4O9S. Mole weight: 594.76. Purity: 95%+. Product ID: ACM1334172767. Alfa Chemistry ISO 9001:2015 Certified. Categories: Biotin PEG2 amine.
Biotin-PEG8-azide
Biotin-PEG8-azide is click chemistry reagent for biotinylation of macromolecule Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG8-azide; SCHEMBL21150837; 2363756-34-5; N-(26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; BP-25110. Grade: 0.98. CAS No. 2363756-34-5. Molecular formula: C28H52N6O10S. Mole weight: 664.8.
Biotin-PEG8-NHS ester. Uses: Designed for use in research and industrial production. Product Category: Biotin PEG Linkers. CAS No. 2143968-03-8. Molecular formula: C33H56N4O14S. Mole weight: 764.88. Purity: 95%+. Product ID: ACM2143968038. Alfa Chemistry ISO 9001:2015 Certified.
Biotin-PEG8-NHS ester
Biotin-PEG8-NHS ester is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-NHS Ester. Grade: >97%. Molecular formula: C33H56N4SO14. Mole weight: 764.88.
Biotin-PEG8-propionic acid
Biotin-PEG8-propionic acid is a biotin-PEG derivative for biotinylation. The biotin group serves as an affinity label towards the proteins avidin and streptavidin. Synonyms: (+)-Biotin-PEG8-CH2CH2COOH; (+)-Biotin-PEG8-propionic acid; Biotin-PEG8-CH2CH2COOH. Grade: >97%. Molecular formula: C29H53N3SO12. Mole weight: 667.81.
Biotin-PEG8-Vidarabine is a PEG-based linker that incorporates adenosine analog Vidarabine. Vidarabine is an antiviral agent which is active against herpes simplex and varicella zoster viruses. Synonyms: Biotin-PEG8-Vidarabine|HY-145246|CS-0370379. Grade: >98%. Molecular formula: C36H60N8O13S. Mole weight: 844.97.
Biotin-PEG9-CH2CH2COOH
Biotin-PEG9-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG9-CH2CH2COOH can be used in the synthesis of a series of PROTACs. Molecular formula: C31H57N3O13S. Mole weight: 711.86.
Biotin-PEG9-NHS Ester
Biotin-PEG9-NHS Ester is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG9-NHS Ester can be used in the synthesis of a series of PROTACs. Molecular formula: C35H60N4O15S. Mole weight: 808.93.
Biotin-PEG-AC, MW 1k-10k
Biotin-PEG-AC is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials.Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-AC can be used as argeted markers for small molecules or materials. Mole weight: Customizable.
Biotin-PEG-azide, MW 1K-10K
Biotin-PEG-azide, MW 1,000 is a biotinylation reagent which has strong binding affinity to avidin or streptavidin. The azide moiety can react with terminal alkyne via copper click reaction or with cyclooctyne (BCN/DBCO) via copper-free click chemistry. Please contact us for GMP-grade inquiries. Synonyms: Biotin-PEG1-azide; 1204085-48-2; N-[2-(2-Azidoethoxy)ethyl]-biotinamide; BIOTIN-PEG-AZIDE; SCHEMBL23947625; DTXSID701118138; 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(2-azidoethoxy)ethyl]pentanamide; AKOS040756543. Molecular formula: C14H24N6O3S. Mole weight: 356.45.
Biotin-PEG-Biotin
Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 194920-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140656A.
Biotin-PEG-Biotin, MW 600-35k
Biotin-PEG-Biotin has two activated terminal groups. Biotin groups are often used in labeling. Homobifunctionalized PEG derivatives have wide applications in peptides, proteins, lipids, other small molecules and surface modifications. Drug PEGylation can alter its dispersity and solubility in aqueous solutions. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Synonyms: Biotin-PEG-Biotin; SCHEMBL15216220; Biotin-PEG-Biotin, MW 1,000; Biotin-PEG-Biotin, MW 2,000; Biotin-PEG-Biotin, MW 3,400; Biotin-PEG-Biotin, MW 5,000; Biotin-PEG-Biotin, MW 10,000; HY-140656A. Molecular formula: C26H44N6O6S2. Mole weight: Customizable.
Biotin-PEG-CH2CO2H, MW 1K-10K
Biotin-PEG-CH2CO2H, MW 1,000 is a carboxyl polyPEG used for biotinylation due to its strong binding with avidin/streptavidin. The carboxyl is reactive with amine in the presence of activating agent, such as HATU or EDC, to generate a covalent amide bond. Please contact us for GMP-grade inquiries.
Biotin-PEG-COOH, MW 1k-10k
Biotin-PEG-AC is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials.Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-AC can be used as argeted markers for small molecules or materials. Mole weight: Customizable.
Biotin-PEG-DMG
Biotin-PEG-DMG is a lipid used in the form of lipid nanoparticles. Synonyms: α-Biotin-ω-dimyristoyl glycerol poly(ethylene glycol).
Biotin-PEG-MAL, MW 1k-10k
Biotin-PEG-MAL is a linear heterobifunctional PEGylation reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-MAL can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-NH2, MW 1k-10k
Biotin-PEG-NH2 is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-NH2 can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-NHS, MW 1k-4k
Biotin-PEG-NHS ester is a heterobifunctional PEG derivative containing a biotin group and an NHS ester group. Mole weight: Customizable.
Biotin-PEG-OH, MW 1k-10k
Biotin-PEG-OH is a linear heterobifunctional PEGylation reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-OH can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-PLGA
Biotin-PEG-PLGA. Synonyms: Folate-poly(ethylene glycol)-b-poly(lactide-co-glycolide). Product ID: MSMN-047. Category: Raw Materials.
Biotin-PEG-SCM, MW 1k-10k
Biotin-PEG-SCM with two different activated terminal groups, a biotin and a succinimidyl NHS ester. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-SCM can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-SH, MW 1k-10k
Biotin-PEG-SH with two different activated terminal groups is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. The other terminal group participates in kinds of active reactions. Biotin-PEG-SH can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-Silane, MW 1k-10k
Biotin-PEG-Silane is a linear heterobifunctional PEG reagent with two different activated terminal groups. It is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Biotin terminal group can label specific molecules, structures or tissues. Silane can modify the surface of metallic materials. Biotin-PEG-Silane can be used as argeted markers for proteins or materials. Mole weight: Customizable.
Biotin-PEG-Succinimidyl Carbonate, MW 5K
Biotin-PEG-Succinimidyl Carbonate, MW 5,000 is a PEG polymer active ester which is reactive with amine via formation of amide bond. The biotin has strong binding affinity with streptavadin and avadin. Please contact us for GMP-grade inquiries.
Biotin-PEG-Succinimidyl glutaramide, MW 3.5k
Biotin-PEG-succinimidyl glutaramide is a heterobifunctional PEG derivative containing a biotin group and a succinimidyl glutaramide group.
Biotin-PEG-Succinimidyl Valerate, MW 3.4K-5K
Biotin-PEG-Succinimidyl Valerate, MW 3,400 is a biotin PEGylation reagent with an NHS ester which is reactive specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form a stable amide bond. Please contact us for GMP-grade inquiries.
Biotin-PEG-Thiol (MW 2000)
Biotin-PEG-Thiol (MW 2000) is an active compound. Biotin-PEG-Thiol (MW 2000) is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. Biotin-PEG-Thiol (MW 2000) can modify biomolecules, proteins, peptides and other small molecule materials. Biotin-PEG-Thiol (MW 2000) is widely used in the research of agent release and nano new materials[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-148263.
Biotin pentafluorophenyl ester
Biotin pentafluorophenyl ester is used to prepare melampomagnolide B as an antileukemic sesquiterpene. Synonyms: Biotin-PFP ester; (+)-Biotin-PFP-ester; Perfluorophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate; Biotin-PFP; Biotin-OPFP; Pentafluorophenyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; AK103675; EZ-Link PFP-Biotin; SCHEMBL140972; D-Biotin pentafluorophenyl ester; CTK8C0381; DTXSID80455998; (+)-Biotin pentafluorophenyl ester; (3aS,3abeta,6abeta)-2-Oxohexahydro-1H-thieno[3,4-d]imidazole-4alpha-pentanoic acid; pentafluorophenyl ester; PFP-Biotin. Grade: 98 % (HPLC). CAS No. 120550-35-8. Molecular formula: C16H15F5N2O3S. Mole weight: 410.36.
Biotin-Phosphatidic Acid
Biotin-Phosphatidic Acid is a biotinylated conjugate of Phosphatidic Acid. Phosphatidic acid (PA) is a major component of cell membranes with important biophysical, metabolic, and signaling roles. PA has been implicated in many aspects of animal cell biochemistry and physiology, including cell proliferation and differentiation, cell transformation, tumor progression and survival signaling. Synonyms: Biotin-PA. Molecular formula: C41H75N4O11PS. Mole weight: 863.10.
Biotin-Phosphatidylcholine
Biotin-Phosphatidylcholine is a functionalized phosphatidylcholine with biotin conjugated to the sn1 acyl chain. Phosphatidylcholine (PC) is generally the most abundant lipid in animal cell membranes providing structural framework. PC is also the primary substrate of Phospholipase D enzymes which produce the signaling lipids - phosphatidic acid and lysophosphatidic acid. Synonyms: Biotin-PC. Grade: >95%. Molecular formula: C46H86N5O11PS. Mole weight: 948.20.
Biotin-Phosphatidylethanol (12:0/18:1)
Biotin-PEth is the first PEth analog used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily in the liver by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is the longest-lived circulating ethanol metabolite yet identified. Synonyms: Biotin-PEth (12:0/18:1). Molecular formula: C51H93N4O11PS. Mole weight: 1001.36.
Biotin-Phosphatidylethanol (6:0/16:0)
Biotin-PEth is the first PEth analog used to build biological assays testing for serum and in vitro PEth levels. PEth is formed primarily in the liver by transphosphatidylation of phosphatidylcholine (PC) by phospholipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is the longest-lived circulating ethanol metabolite yet identified. Synonyms: Biotin-PEth (6:0/16:0). Molecular formula: C43H78N4O11PS. Mole weight: 890.15.
Biotin-Phosphatidylethanolamine
Biotin-Phosphatidylethanolamine is a biotinylated conjugate of phosphatidylethanolamine. Phosphatidylethanolamine (PE) is formed primarily in the reaction of CDP-ethanolamine and diacylglycerol. PE is one of the major components of cell membranes in bacteria and in nervous system. Synonyms: Biotin-PE. Molecular formula: C43H80N5O11PS. Mole weight: 906.17.
Biotin-Phosphatidylglycerol
Biotin-Phosphatidylglycerol is a biotinylated conjugate of phosphatidylglycerol (PG). Phosphatidylglycerol (PG) is a minor component (1-2%) of most of cell membranes. It can be found at higher concentrations (up to 11% of the total lipid content) in lung surfactant. PG is also used by cells as an intermediate in cardiolipin synthesis. Bacterial membranes contain up to 20% of PG. Synonyms: Biotin-PG. Molecular formula: C44H81N4O13PS. Mole weight: 937.18.
Biotin Phosphatidylinositol
Biotin Phosphatidylinositol is a water-soluble analog of Phosphatidylinositol labelled with biotin at the sn-1 position. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol. Synonyms: Biotin PI. Grade: >95%. Molecular formula: C37H64N4NaO16PS. Mole weight: 906.95.
Biotin Phosphatidylinositol 3,4-bisphosphate
Biotin Phosphatidylinositol 3,4-bisphosphate is a water-soluble analog of PI(3,4)P2 labelled with biotin at the sn-1 position. PI(3,4)P2 is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. Synonyms: Biotin PI(3,4)P2. Grade: >95%. Molecular formula: C37H62N4Na5O22P3S. Mole weight: 1153.84.
Biotin Phosphatidylinositol 3,5-bisphosphate
Biotin Phosphatidylinositol 3,5-bisphosphate is a water-soluble analog of PI(3,5)P2 labelled with biotin at the sn-1 position. PI(3,5)P2 is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3,5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease). Synonyms: Biotin PI(3,5)P2. Grade: >95%. Molecular formula: C37H62N4Na5O22P3S. Mole weight: 1154.84.