A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
D-2'-Deoxyribofuranosyl-3-guanylurea is used in the synthesis of N4-alkyl-5-azacytidines as mutagenic agents. Synonyms: N-(Aminoiminomethyl)-N-(2-deoxy-D-erythro-pentofuranosyl)urea; Decitabine deformyl impurity formate; Urea, N-(aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)-; N-(Aminoiminomethyl)-N'-(2-deoxy-D-erythro-pentofuranosyl)urea. Grade: > 95%. CAS No. 570410-72-9. Molecular formula: C7H14N4O4. Mole weight: 218.21.
D-2'-Deoxyribopyranosyl-3-guanylurea (α/β-Mixture) can be obtained from 5-Aza-2'-deoxy Cytidine which can be used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines. Grade: 98%. Molecular formula: C7H14N4O4. Mole weight: 218.21.
The enzymes, characterized from bacteria (Peptoclostridium difficile, Enterococcus faecalis and from lactic acid bacteria) prefer substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain. It also utilizes phenylpyruvate. The enzyme from the halophilic archaeon Haloferax mediterranei prefers substrates with a main chain of 3-4 carbons (pyruvate and 2-oxobutanoate). cf. EC 1.1.1.272, (D)-2-hydroxyacid dehydrogenase (NADP+). Group: Enzymes. Synonyms: LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.1.345. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0260; D-2-hydroxyacid dehydrogenase (NAD+); EC 1.1.1.345; LdhA; HdhD; D-2-hydroxyisocaproate dehydrogenase; R-HicDH; D-HicDH; (R)-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase; (R)-2-hydroxyisocaproate dehydrogenase; D-mandelate dehydrogenase (ambiguous). Cat No: EXWM-0260.
D-2-hydroxyacid dehydrogenase (NADP+)
This enzyme, characterized from the halophilic archaeon Haloferax mediterranei and the mold Aspergillus oryzae, catalyses a stereospecific reduction of 2-oxocarboxylic acids into the corresponding D-2-hydroxycarboxylic acids. The enzyme prefers substrates with a main chain of 5 carbons (such as 4-methyl-2-oxopentanoate) to those with a shorter chain, and can use NADH with much lower efficiency. cf. EC 1.1.1.345, (D)-2-hydroxyacid dehydrogenase (NAD+). Group: Enzymes. Synonyms: ddh (gene name). Enzyme Commission Number: EC 1.1.1.272. CAS No. 81210-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0179; D-2-hydroxyacid dehydrogenase (NADP+); EC 1.1.1.272; 81210-65-3; ddh (gene name). Cat No: EXWM-0179.
D-2-hydroxyacid dehydrogenase (quinone)
The enzyme from mammalian kidney contains one mole of FAD per mole of enzyme.(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors. Group: Enzymes. Synonyms: (R)-2-hydroxy acid dehydrogenase; (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase; D-lactate dehydrogenase (ambiguous). Enzyme Commission Number: EC 1.1.5.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0428; D-2-hydroxyacid dehydrogenase (quinone); EC 1.1.5.10; (R)-2-hydroxy acid dehydrogenase; (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase; D-lactate dehydrogenase (ambiguous). Cat No: EXWM-0428.
D-2-hydroxyglutarate dehydrogenase
The enzyme, which has been characterized from the plant Arabidopsis thaliana, is highly specific for (R)-2-hydroxyglutarate. It has low activity with (R)-lactate, (R)-2-hydroxybutyrate and meso-tartrate, and no activity with the (S) isomers. Group: Enzymes. Synonyms: AtD-2HGDH. Enzyme Commission Number: EC 1.1.99.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0467; D-2-hydroxyglutarate dehydrogenase; EC 1.1.99.39; AtD-2HGDH. Cat No: EXWM-0467.
D-2-Hydroxyglutarate Dehydrogenase from Acidaminococcus fermentans, Recombinant
D-2-hydroxyglutarate (D2HG) level is significantly increased in metabolic diseases and various cancers such as acute myeloid leukemia. Studies suggest that the detection of D2HG serves as a biomarker assay related to IDH (isocitrate dehydrogenase) mutations. D2HGDH is a special NAD-dependent enzyme which reacts with D2HG specifically and converts D2HG to α-ketoglutarate. D2HGDH is a key enzyme to distinguish between two metabolites, D2HG and L-2-hydroxyglutarate (L2HG), during biomarker assays. Group: Enzymes. Synonyms: D-2-hydroxyglutarate dehydrogenase; D2HGDH; D2HGD. Enzyme Commission Number: EC 1.1.99.39. Purity: > 99% by SDS - PAGE. Mole weight: 39 kDa. Activity: > 90,000 mU/mg. Storage: Can be stored at 4°C up to 2 weeks. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. Form: Lyophilized in 50mM Tris, pH 8 without any additives. Source: E. coli. Species: Acidaminococcus fermentans. D-2-hydroxyglutarate dehydrogenase; D2HGDH; D2HGD. Cat No: NATE-1660.
This product with the indicated enzyme activity was briefly purified from engineered E. coli. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.x. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Hydroxyisocaproic Acid Dehydrogenase. Pack: 100ml. Cat No: NATE-1798.
D(+)-2-Octanol. Synonyms: (s)-2-octano;(S)-octan-2-ol;D(+)-2-OCTANOL;D-2-OCTANOL;(S)-(+)-2-HYDROXYOCTANE;(S)-2-HYDROXYOCTANE;(S)-(+)-2-OCTANOL;(S)-2-OCTANOL. CAS No. 6169-6-8. Pack Sizes: 1 kg. Product ID: CDF4-0063. Molecular formula: C8H18O. Category: Flavor Enhancers. Product Keywords: Food Ingredients; Flavor Enhancers; D(+)-2-Octanol; CDF4-0063; 6169-06-8; C8H18O; 228-213-6; 6169-06-8. Purity: 0.98. Color: Colorless to Almost colorless. EC Number: 228-213-6. Physical State: Liquid. Storage: Sealed in dry,Room Temperature. Boiling Point: 175 °C (lit.). Melting Point: -61.15°C (estimate). Product Description: 2-Octanol is a fatty alcohol. It is directly produced from vegetal chemistry. In industry, it is produced by a cracking process from castor oil.
D-(-)-2-Phenylglycine
D-(-)-2-Phenylglycine is the derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. It is also an impurity of Ampicillin and Cefaclor. Synonyms: Ampicillin EP Impurity L; Cefaclor EP Impurity A; (-)-(R)-Phenylglycine; (-)-Phenylglycine; (2R)-Amino-2-phenylethanoic Acid; (R)-(-)-2-Phenylglycine; (R)-2-Amino-2-phenylacetic Acid; (R)-2-Amino-2-phenylethanoic Acid; (R)-2-Phenyl-2-aminoethanoic Acid; (R)-2-Phenylglycine; (R)-2-Phenylglycine. Grade: ≥ 99% (Assay). CAS No. 875-74-1. Molecular formula: C8H9NO2. Mole weight: 151.17.
D-(-)-2-Phenylglycine Cephalexinate
D-(-)-2-Phenylglycine Cephalexinate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C24H24N4O5S, Molecular Weight: 480.54. US Biological Life Sciences.
Worldwide
D-(-)-2-Phenylglycine-d5
Labeled D-Phenylglycine. Group: Biochemicals. Alternative Names: (αR)-α-Amino-benzeneacetic-d5 Acid; D-2-Phenyl-glycine-d5; (-)-(R)-Phenylglycine-d5; (-)-Phenylglycine-d5; (2R)-Amino-2-phenylethanoic-d5 Acid. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
D3024
fast cooling of the rotor and low energy consumption. 3-layer sealed rotors ensure safe centifugation. Brushless motor drive, maintenance free. Safety features include door interlock; excessive speed and temperature detection; automatic self-diagnostics. Outstanding aluminum alloy rotors fully autoclavable at 121°C temperature and high pressure disinfection. Five rotors are optional complete with 24 places 1.5/2.0mL tubes,5.0mL, 0.2mL and 0.5mL tubes with adapters. Categories: Labooratory Centrifuges.
D-3263 is a TRPM8 agonist ( transient receptor potential melastatin member 8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer. Synonyms: 3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one; 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥95%. CAS No. 947257-66-1. Molecular formula: C21H31N3O3. Mole weight: 373.49.
D-3263 hydrochloride
D-3263 hydrochloride is an enteric-coated and orally bioavailable agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity. Synonyms: 3-(2-Amino-ethyl)-1(R)-((2(S)-isopropyl-5(R)-methylcyclohexanecarbonyl))-5-methoxy-1,3-dihydro-benzoimidazol-2-one hydrochloride; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one hydrochloride (1:1); 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, hydrochloride (1:1). Grade: ≥98%. CAS No. 1008763-54-9. Molecular formula: C21H32ClN3O3. Mole weight: 409.95.
D-3263 hydrochloride
D-3263 hydrochloride is an enteric-coated, orally bioavailable (transient receptor potential melastatin member 8) TRPM8 agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 1008763-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16162A.
D-3,5-Difluorophenylalanine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
D-3-Amino methyl phenylalanine
D-3-Amino methyl phenylalanine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 1217607-94-7. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
D3-βArr
D3-βArr is a positive allosteric modulator of thyrotropin (TSH) receptor. D3-βArr does not activate Beta-Arr 1 translocation to the glucagon-like peptide 1 receptor (GLP-1R) in CHO-K1-GLP1R-Beta Arrestin 1 cells. Synonyms: NCGC00379308; D3-betaArr. CAS No. 662164-09-2. Molecular formula: C20H23N5. Mole weight: 333.4.
D-3-HYDROXYBUTYRATE DEHYDROGENASE. Synonyms: D-3-HYDROXYBUTYRATE: NAD OXIDOREDUCTASE;BETA-HYDROXYBUTYRATE DEHYDROGENASE;BETA-HYDROXYBUTYRATE DEHYDROGENASE TYPE V;3-HBDH;3-HYDROXYBUTYRATE DEHYDROGENASE;(R)-3-HYDROXYBUTANOATE: NAD+ OXIDOREDUCTASE;[R]-3-HYDROXYBUTANOATE: NAD+ OXIDOREDUCTASE TYPE V;B-HYDROXYBUTYRATE DEHYDROGENASE TYPE IV FROM PSEUDO. CAS No. 9028-38-0. Pack Sizes: 1 kg. Product ID: CDF4-0049. Molecular formula: NULL. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; D-3-HYDROXYBUTYRATE DEHYDROGENASE; CDF4-0049; 9028-38-0; 232-830-6; 9028-38-0. Purity: 0.99. EC Number: 232-830-6. Physical State: Lyophilized Powder. Storage: -20°C. Product Description: D-β-hydroxybutyrate dehydrogenase (BDH) is a membrane bound lipid-requiring enzyme.
D-3-hydroxybutyrate dehydrogenase from Microorganism
In enzymology, a 3-hydroxybutyrate dehydrogenase (EC 1.1.1.30) is an enzyme that catalyzes the chemical reaction: (R)-3-hydroxybutanoate + NAD+ ? acetoacetate + NADH + H+. Thus, the two substrates of this enzyme are (R)-3-hydroxybutanoate and NAD+, whereas its three products are acetoacetate, NADH, and H+. This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. This enzyme participates in synthesis and degradation of ketone bodies and butanoate metabolism. Group: Enzymes. Synonyms: (R)-3-hydroxybutanoate: NAD+ oxidoreductase; NAD+-beta-hydroxybutyrate dehydro. Enzyme Commission Number: EC 1.1.1.30. CAS No. 9028-38-0. Mole weight: 27.5 kDa (SDS-PAGE). Activity: >300U/mg. Storage: Store at -20°C. Form: Yellowish powder, lyophilized. Source: Microorganism. (R)-3-hydroxybutanoate: NAD+ oxidoreductase; NAD+-beta-hydroxybutyrate dehydrogenase; hydroxybutyrate oxidoreductase; beta-hydroxybutyrate dehydrogenase; D-beta-hydroxybutyrate dehydrogenase; D-3-hydroxybutyrate dehydrogenase; D-( - )-3-hydroxybutyrate dehydrogenase; beta-hydroxybutyric acid dehydrogenase; 3-D-hydroxybutyrate dehydrogenase; beta-hydroxybutyric dehydrogenase; EC 1.1.1.30; 9028-38-0; HBDH; β-Hydroxybutyrate Dehydrogenase; 3-Hydroxybutyrate Dehydrogenase. Cat No: NATE-1714.
D-3-Methoxyphenylalanine
D-3-Methoxyphenylalanine. Group: Biochemicals. Alternative Names: D-Phe(3-OMe)-OH; m-Methoxy-D-phenylalanine; (R) -2-Amino-3- (3-methoxyphenyl) propionic acid. Grades: Highly Purified. CAS No. 145306-65-6. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
D-3-Methoxyphenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
d(-)3-Phosphoglyceric acid calcium
d(-)3-Phosphoglyceric acid calcium. Alternative Names: D(-)3-PHOSPHOGLYCERIC ACID CALCIUM. CAS No. 108347-88-2. Purity: 96%. Product ID: ACM108347882. Molecular formula: C6H8Ca3O14P2. Mole weight: 486.300842. Alfa Chemistry - ISO 9001:32057 Certified.
D-(-)-3-Phosphoglyceric acid disodium
D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 3-Phospho-D-glyceric acid disodium. CAS No. 80731-10-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141412.
D3-Thymidine
D3-Thymidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 74848-84-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H11N2O5D3. US Biological Life Sciences.
D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1). Synonyms: Casein Kinase I Inhibitor; D 4476; D-4476. Grade: >98%. CAS No. 301836-43-1. Molecular formula: C23H18N4O3. Mole weight: 398.41.
D4476
D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Casein Kinase I Inhibitor. CAS No. 301836-43-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10324.
D4-abiraterone
D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite. CAS No. 154229-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-109619.
D-4-Chlorophenylglycine hydrochloride. Alternative Names: D-4-CHLOROPHENYLGLYCINE HCL. CAS No. 108392-76-3. Product ID: ACM108392763. Molecular formula: C8H9Cl2NO2. Alfa Chemistry - ISO 9001:32057 Certified.
D-4-Fluorophenylglycine hydrochloride
D-4-Fluorophenylglycine hydrochloride. Alternative Names: D-4-FLUOROPHENYLGLYCINE HCL. CAS No. 144744-41-2. Product ID: ACM144744412. Molecular formula: C8H9ClFNO2. Alfa Chemistry - ISO 9001:32057 Certified.
D-4-Hydroxyphenylalanine-[3,3-d2]
D-4-Hydroxyphenylalanine-[3,3-d2] is a labelled D-tyrosine. Tyrosine is a non-essential amino acid synthesized from phenylalanine. It is the precursor of some neurotransmitters. Synonyms: D-Tyrosine-d2; p-Hydroxyphenyl-D-alanine-d2; H-D-Tyr-OH-d2. Grade: 95% by HPLC; 98% atom D. CAS No. 1202064-22-9. Molecular formula: C9H9D2NO3. Mole weight: 183.2.
D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3
D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 is a labelled D-tyrosine. Tyrosine is a non-essential amino acid synthesized from phenylalanine. It is the precursor of some neurotransmitters. Synonyms: D-Tyrosine-d7; p-Hydroxyphenyl-D-alanine-d7; H-D-Tyr-OH-d7. Grade: 95% by HPLC; 98% atom D. CAS No. 1426174-46-0. Molecular formula: HOC6D4CD2CD(NH2)COOH. Mole weight: 188.23.
D(-)-4-Hydroxyphenylglycine dane salt
D(-)-4-Hydroxyphenylglycine dane salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 69416-61-1. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C13H14NO5·K. US Biological Life Sciences.