A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
D-Glycero-D-manno-heptose is a crucial compound used for synthesizing antibiotics and antiviral drugs. It plays a vital role in studying infectious diseases caused by bacteria or viruses. Its unique structure makes it an essential component in the development of research against various drug-resistant strains. Synonyms: (2S,3S,4R,5R,6R)-2,3,4,5,6,7-Hexahydroxyheptanal; SCHEMBL607071. CAS No. 1961-73-5. Molecular formula: C7H14O7. Mole weight: 210.20.
D-Glycero-D-talo-heptitol
D-Glycero-D-talo-heptitol is an intriguing and versatile compound, used in studying a myriad of metabolic disorders and diseases. With its exceptional role as a precursor in drug synthesis, this compound offers potential in studying dire conditions like diabetes, cancer and cardiovascular ailments. Synonyms: Volemitol; D-Glycero-D-manno-heptitol. CAS No. 488-38-0. Molecular formula: C7H16O7. Mole weight: 212.20.
D-Glycero-D-talo-heptose
D-Glycero-D-talo-heptose is a biochemically significant entity with its indispensability steming from its pivotal involvement in the synthetic pathways of biologically active constituents and pharmaceutical compounds. Notably, this substance assumes paramount importance in the research of efficacious remedies for specific conditions encompassing bacterial affections, oncological disorders and pathological inflammations. Synonyms: D-Glycero-D-taloheptose. CAS No. 10589-31-8. Molecular formula: C7H14O7. Mole weight: 210.18.
D-glycerol-[1-13C]
D-glycerol-[1-13C] is the labelled analogue of Glycerol. Glycerol can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. Synonyms: D-[1-13C]glycerol; D-glycerol-1-13C; 1,2,3-Propanetriol-1-13C; 1,3-dihydroxy-2-propanol-1-13C; Propanetriol-1-13C; 1,2,3-Trihydroxypropane-1-13C; Bulbold-1-13C; Cognis G-1-13C; Cristal-1-13C. Molecular formula: C2[13C]H8O3. Mole weight: 93.09.
D-Glycerol-[3-13C]
D-Glycerol-[3-13C] is the labelled analogue of Glycerol. Glycerol can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. Synonyms: 1,2,3-Propanetriol-3-13C; 1,3-dihydroxy-3-propanol-1-13C; Propanetriol-3-13C; 1,2,3-Trihydroxypropane-3-13C; Bulbold-3-13C; Cognis G-3-13C; Cristal-3-13C; DG-3-13C; DG Glycerin-3-13C. CAS No. 154278-20-3. Molecular formula: C2[13C]H8O3. Mole weight: 93.09.
dG-Me Phosphonamidite is a crucial recompound primarily employed for the synthesis of modified nucleotides for DNA research and drug discovery. This product plays a vital role in the design and generation of nucleic acid analogs, which target specific diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite. Molecular formula: C42H53N6O7P. Mole weight: 784.89.
DGN462 is a potent DNA alkylating agent with antitumor activity, such as against acute myeloid leukemia (AML). DGN462 can be used as an ADC toxin molecule to synthesize ADC. Synonyms: DGN-462; IMGN-779; IMGN779-linker; (5aS)-10-Methoxy-9-({3-[{2-[2-(2-methoxyethoxy)ethoxy]ethyl}(2-methyl-2-sulfanylpropyl)amino]-5-({[(5aS)-10-methoxy-12-oxo-5a,6,7,12-tetrahydro-5H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy}methyl)benzyl}oxy)-5,5a-dihydro-12H-indolo[2,1-c][1,4]benzodiazepin-12-one; 6H-Indolo[2,1-c][1,4]benzodiazepin-6-one, 9-[[3-[[[(12aS)-12a,13-dihydro-8-methoxy-6-oxo-6H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy]methyl]-5-[(2-mercapto-2-methylpropyl)[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amino]phenyl]methoxy]-11,12,12a,13-tetrahydro-8-methoxy-, (12aS)-; (12aS)-9-[[3-[[[(12aS)-12a,13-Dihydro-8-methoxy-6-oxo-6H-indolo[2,1-c][1,4]benzodiazepin-9-yl]oxy]methyl]-5-[(2-mercapto-2-methylpropyl)[2-[2-(2-methoxyethoxy)ethoxy]ethyl]amino]phenyl]methoxy]-11,12,12a,13-tetrahydro-8-methoxy-6H-indolo[2,1-c][1,4]benzodiazepin-6-one. Grade: ≥95%. CAS No. 1394079-41-4. Molecular formula: C53H59N5O9S. Mole weight: 942.13.
dG(N-Pac) CE Phosphoramidite
dG(N-Pac) CE Phosphoramidite is a modified phosphoramidite reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of deoxyguanosine (dG) with an N-phenoxyacetyl (N-Pac) protecting group. This protecting group is part of the UltraMILD chemistry, which allows for the deprotection of oligonucleotides under milder conditions compared to standard protocols. Synonyms: dG(N-Pac) Phosphoramidite; dG(Pac) CE Phosphoramidite; 5'-O-DMT-N2-phenoxyacetyl-2'-Deoxy-guanosine 3'-CE phosphoramidite; 2'-Deoxy-5'-O-DMT-N2-phenoxyacetylguanosine 3'-CE phosphoramidite; Pac-dG-CEP; DMT-dG(Pac) Phosphoramidite; dG(Pac) 3'-CE phosphoramidite; DMT-dG(Pac)-CE Phosphoramidite; N2-phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-CE-Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥97%. CAS No. 110522-83-3. Molecular formula: C48H54N7O9P. Mole weight: 903.97.
dGpCpp
dGpCpp, a pyrophosphate analog employed in biomedical research for studying RNA and DNA polymerase activity, possesses anti-proliferative action against cancerous cells and showcases potential benefits in certain viral infections. Notably, the compound serves as an inhibitor of protein synthesis through the stimulation of mRNA degradation and the targeting of elongation factors. Synonyms: (dGMPCPP); 2'-Deoxyguanosine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 941569-34-2. Molecular formula: C11H18N5O12P3 (free acid). Mole weight: 505.21 (free acid).
dGpdA
dGpdA, a potent nucleoside analog employed in biomedicine for alleviating viral infections, including varicella-zoster virus and herpes simplex virus type 1 and 2, acts as an inhibitor of viral DNA polymerase, thereby prohibiting viral replication. Harnessing unparalleled therapeutic benefits, it also demonstrates breakthrough results in the effective treatment of solid tumors, thanks to its unique ability to stimulate apoptosis in cancer cells. Synonyms: dGpdA DNA Dinucleotide (5'-3'). Grade: ≥95% by AX-HPLC. Molecular formula: C20H25N10O9P. Mole weight: 580.40.
dGpNHpp
dGpNHpp, a minuscule molecule, is capable of disrupting protein-protein interactions with a specific focus on the nucleotide binding domain (NBD) of CFTR, a protein afflicted with mutation in cystic fibrosis. Its viability as a therapeutic agent lies in its probable ability to rectify the rogue folding and movement patterns of the mutated CFTR protein while opening up new dimensions unconquered until now. Synonyms: (dGMPNPP); 2'-Deoxyguanosine-5'-[(α,β)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 756797-73-6. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.19 (free acid).
dGppNHp
dGppNHp is a modified nucleotide widely employed in studying intricate protein kinase signaling pathways. Serving as a non-hydrolyzable analog of GTP, this indispensable biochemical entity assumes a pivotal role in experimental investigations, particularly those concerning GTPases. Synonyms: (dGMPPNP); 2'-Deoxyguanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grade: ≥ 90% by HPLC. Molecular formula: C10H17N6O12P3 (free acid). Mole weight: 506.20 (free acid).
D-GsMTx4
D-GsMTx4 is a mechanosensitive and stretch-activated ion channel inhibitor. It is used as a tool for identifying the role of these excitatory MSCs in normal physiology and pathology. Grade: 95%. Molecular formula: C185H273N49O45S6. Mole weight: 4095.86.
dG-Thiophosphoramidite
dG-Thiophosphoramidite, a premium reagent, is widely utilized in biomedical research. Its application lies in the synthesis of DNA oligonucleotides equipped with thiophosphate links, rendering them incredibly potent agents for combating diseases such as cancer and viral infections, courtesy of enhanced nuclease resistance. Researchers entrust this reagent for its dependable performance as it is easily accessible and has a sound reputation. Synonyms: 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C48H53N6O8PS2. Mole weight: 937.07.
dGTP
The lyophilized form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Synonyms: Deoxyguanosine Triphosphate; Deoxy-GTP; Deoxyguanosine 5'-Triphosphate; 2'-Deoxyguanosine 5'-Triphosphate; 5'-DGTP; 2'-deoxy-guanosine 5'-(tetrahydrogen triphosphate); Guanosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-. Grade: ≥95% by HPLC. CAS No. 2564-35-4. Molecular formula: C10H16N5O13P3. Mole weight: 507.18.
dGTPαS
dGTPαS, a nucleotide analog, is commonly employed in enzymatic assays that investigate the mechanisms of G-protein catalyzed nucleotide exchange reactions. In addition to this, it finds widespread application as a substrate for DNA polymerase and sequencing techniques, including PCR. Its multifaceted nature makes it an essential component of numerous research studies. Synonyms: 2'-Deoxyguanosine-5'-(α-thio)-triphosphate, Sodium salt (1 : 1 Mixture of Rp and Sp isomers). Grade: ≥ 95% by HPLC. CAS No. 82337-56-2. Molecular formula: C10H16N5O12P3S (free acid). Mole weight: 523.24 (free acid).
dGTPase
Also acts on GTP. Group: Enzymes. Synonyms: deoxy-GTPase; deoxyguanosine 5-triphosphate triphosphohydrolase; deoxyguanosine triphosphatase; deoxyguanosine triphosphate triphosphohydrolase. Enzyme Commission Number: EC 3.1.5.1. CAS No. 9025-63-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3741; dGTPase; EC 3.1.5.1; 9025-63-2; deoxy-GTPase; deoxyguanosine 5-triphosphate triphosphohydrolase; deoxyguanosine triphosphatase; deoxyguanosine triphosphate triphosphohydrolase. Cat No: EXWM-3741.
dGTP solution - Lithium Salt
The lithium salt solution form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
dGTP solution - Sodium Salt
The sodium salt solution form of dGTP. dGTP is a nucleoside triphosphate used in the synthesis of DNA. Grade: ≥ 99% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid).
D-Gulonic acid-1,4-lactone is a vital compound found in the biomedical industry. It plays a crucial role in the synthesis of L-ascorbic acid (vitamin C). With its antioxidant properties, D-Gulonic acid-1,4-lactone is utilized in various drugs and treatments for diseases associated with vitamin C deficiency such as scurvy. It serves as a precursor in the production of essential antioxidants, supporting overall health and immune function. Synonyms: D-Gulonolactone. CAS No. 6322-7-2. Molecular formula: C6H10O6. Mole weight: 178.14.
D-Gulose
D-Gulose is a pivotal biomedical resource, playing an eminent role in studying various metabolic disorders and diabetes. With its profound impact on energy metabolism and carbohydrate assimilation, it acts as a vital precursor in the synthesis of D-gluconic acid. Synonyms: aldehydo-D-gulose; (3R,4R,5R,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol. CAS No. 4205-23-6. Molecular formula: C6H12O6. Mole weight: 180.16.
D-gulose-[1-13C]
D-gulose-[1-13C] is an isotope labelled analogue of D-gulose which is an aldohexose sugar that is very rare in nature but has been found in archaea, bacteria and other eukaryotes. Synonyms: D-[1-13C]gulose; D-gulose-1-13C. CAS No. 70849-25-1. Molecular formula: C5[13C]H12O6. Mole weight: 181.15.
D-gulose-[2-13C]
D-gulose-[2-13C] is an isotope labelled analogue of D-gulose which is an aldohexose sugar that is very rare in nature but has been found in archaea, bacteria and other eukaryotes. Synonyms: D-[2-13C]gulose; D-gulose-2-13C. CAS No. 478529-73-6. Molecular formula: C5[13C]H12O6. Mole weight: 181.15.
D-Gulose-2-13C
Isotope-labelled D-glucose analog is an aldose hexose, very rare in nature, but has been found in archaea, bacteria and other eukaryotes. Mannose is the C-3 epimer of galactose. Molecular formula: C5[13C]H12O6. Mole weight: 181.15.
D-gulose-[UL-13C6]
D-gulose-[UL-13C6] is an isotope labelled analogue of D-gulose which is an aldohexose sugar that is very rare in nature but has been found in archaea, bacteria and other eukaryotes. Synonyms: D-[UL-13C6]gulose; D-gulose-U-13C6. Molecular formula: [13C]6H12O6. Mole weight: 186.11.
Dguo-Phip-[d3]
Dguo-Phip-[d3]. Uses: The deuterated dna adduct formed from n-hydroxy-phip. mutagenic nucleotide incorporation and hindered translocation by a food carcinogen c8-dg adduct in sulfolobus solfataricus p2 dna polymerase iv (dpo4). Synonyms: 2'-Deoxy-8-{[1-(2H3)methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl]amino}guanosine; 8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine; N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-β]pyridine. Grade: 98% atom D. CAS No. 303173-39-9. Molecular formula: C23H20D3N9O4. Mole weight: 492.51.
DGY-06-116
DGY-06-116 is an irreversible covalent Src inhibitor with IC50 of 2.6 nM. DGY-06-116 exhibits potent antiproliferative effects. Synonyms: DGY-06-116; CHEMBL4515441; 2556836-50-9; SCHEMBL22807462; EX-A4311. CAS No. 2556836-50-9. Molecular formula: C32H33ClN8O2. Mole weight: 597.11.
DGY-06-116
DGY-06-116 is an irreversible covalent, selective Src inhibitor with an IC50 of 3nM. DGY-06-116 inhibits FGFR1 with an IC50 of 8340 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2556836-50-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136605.
DGY-09-192
DGY-09-192 is a PROTAC FGFR1/2 degrader (FGFR1: DC50 = 4.35 nM; FGFR2: DC50 = 70 nM). DGY-09-192 preferentially degrades wild-type FGFR1/2 and multiple FGFR2 fusion proteins (including FGFR2-PHGDH and FGFR2-OPTN). DGY-09-192 suppresses downstream FGFR signaling (reducing phosphorylation of FRS2 Y196 and ERK1/2 T202/Y204) in vitro and vivo. DGY-09-192 can be used for the study of FGFR-driven cancers. (Pink: FGFR1/2 ligand (HY-160013), Blue: VHL Ligand (HY-112078), Black: Linker (HY-W020017))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2504949-52-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-165298.
DH 97
DH 97 is a potent MT2 melatonin receptor antagonist (pKi = 8.03) with 89- and 229-fold selectivity over MT1 and GPR50 (melatonin-related orphan receptor) respectively. Synonyms: DH-97; DH 97; DH97; N-Pentanoyl-2-benzyltryptamine; N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide. CAS No. 220339-00-4. Molecular formula: C22H26N2O. Mole weight: 334.46.
DH 97
DH 97. Group: Biochemicals. Grades: Purified. CAS No. 220339-00-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
DHA (Dihydroartemisinin)
DHA (Dihydroartemisinin) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua. Dihydroartemisinin induces autophagy and apoptosis by suppressing NF-κB activation. Group: Inhibitors. Alternative Names: Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol. CAS No. 71939-50-9. Pack Sizes: 100mg. Product ID: S2290. Formula: C15H24O5. Storage Conditions: 2 years -80 in solvent.
United States; Europe
DHA-EPA Omega 3 Fish Oil Powder
DHA-EPA Omega 3 Fish Oil Powder.
CA, FL & NJ
DHA Oil 40% from Algae(Crypthecodinium CohnII)
DHA Oil 40% from Algae(Crypthecodinium CohnII).
CA, FL & NJ
DHA-Paclitaxel
DHA-paclitaxel is a prodrug comprised of the naturally occurring omega-3 fatty acid docosahexaenoic acid (DHA) covalently conjugated to the anti-microtubule agent paclitaxel. Because tumor cells take up DHA, DHA-paclitaxel is delivered directly to tumor tissue, where the paclitaxel moiety binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. DHA-paclitaxel exhibits improved pharmacokinetic and toxicity profiles when compared to conventional paclitaxel and has demonstrated antineoplastic activity in animal models of cancer. Synonyms: Paclitaxel 2'-(all-cis-4,7,10,13,16,19-docosahexaenoate); Taxoprexin; (αR,βS)-β-(Benzoylamino)-α-[[(4Z,7Z,10Z,13Z,16Z,19Z)-1-oxo-4,7,10,13,16,19-docosahexaenyl]oxy]-Benzenepropanoic Acid Mono[(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet. Grade: 98%. CAS No. 199796-52-6. Molecular formula: C69H81NO15. Mole weight: 1164.38.
D-Har2-Eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-DHar-Gly-Asp-Trp-Pro-Cys-NH2(Mpr1&Cys7 bridge); Mpr-DHar-GDWPC-NH2(Mpr&Cys bridge); (D-Homo-Arg)2 Eptifibatide impurity; Mpr-(D-Homo-Arg)-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bond Mpr1/Cys7); Mpr(D-Homo-Arg)GDWPC-NH2 (Disulfide bond Mpr1/Cys7); deamino-Cys-D-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-D-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; Eptifibatide Impurity 4; D-Har Eptifibatide; N6-Amidino-N2-(3-mercaptopropionyl)-D-lysylglycyl-D-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide; (D-Homo-Arg)2 Eptifibatide; D-hArg2-Eptifibatide; [D-hArg]2-Eptifibatide; [D-Har2]-Eptifibatide; L-Cysteinamide, N-(3-mercapto-1-oxopropyl)-6-[(aminoiminomethyl)amino]-D-norleucylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-thioether. Grade: ≥95%. CAS No. 3079028-40-0. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
Dhbp dibromide
Dhbp dibromide. Alternative Names: DHBP dibromide;1,1'-di-n-Heptyl-4,4'-bipyridinium dibromide. CAS No. 6159-5-3. Product ID: ACM1555692. Molecular formula: C24H38Br2N2. Alfa Chemistry - ISO 9001:32057 Certified.
DHBP dibromide
DHBP dibromide blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor. Synonyms: Diheptylviologen dibromide; 1,1'-Diheptyl-4,4'-bipyridinium Dibromide; Diheptylviologen Bromide; Heptylviologen Bromide; Heptylviologen Dibromide; N,N'-Diheptyl-4,4'-bipyridinium Dibromide; N,N'-Diheptyl-4,4'-dipyridinium Dibromide; 1,1'-Diheptyl-[4,4'-bipyridine]-1,1'-diium bromide. Grade: 98%. CAS No. 6159-5-3. Molecular formula: C24H38Br2N2. Mole weight: 514.39.
DHBP dibromide
DHBP dibromide. Group: Biochemicals. Grades: Purified. CAS No. 6159-5-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
DHC-156
DHC-156 is a selective Brachyury small molecule downmodulator. DHC-156 can be used for chordoma research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3115269-32-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157964.
DHEA
DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone. CAS No. 53-43-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-14650.
DHEA(17) (HRP)
Dehydroepiandrosterone is the most abundant adrenal androgen in humans and exists predominately in a sulfated form (DHEAS). DHEA sulfotransferase, known as SULT2A1, converts the androgen precursor DHEA to its inactive sulfate ester, DHEAS. The unconjugated molecules can be converted directly to androgens. Dehydroepiandrosterone is converted to DHEAS in the adrenal glands and liver. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences.
DHEA (Prasterone) (Standard) is the analytical standard of DHEA. This product is intended for research and analytical applications. DHEA is a steroid hormone[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prasterone (Standard); Dehydroisoandrosterone (Standard); Dehydroepiandrosterone (Standard). CAS No. 53-43-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14650R.
D-Heptamannuronic Acid Heptasodium Salt is a natural polysaccharide derived from the marine bacterium, presents itself as a sodium salt form in this product. Synonyms: Hepta-Mannuronic Acid Sodium Salt; β-D-Mannopyranuronic acid, O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-,sodium salt (1:7); O-β-D-Mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-O-β-D-mannopyranuronosyl-(1→4)-β-D-mannopyranuronic acid heptasodium salt. Grade: ≥95% by GPC. Molecular formula: C42H51O43Na7. Mole weight: 1404.76.
DHICA
DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an eumelanin building block, GPR35 agonist and melanin synthesis intermediate. DHICA activates GPR35, triggering dynamic mass redistribution and β-arrestin translocation. DHICA interacts with DNA and interferes with Fpg activity. DHICA promotes the generation of single-strand breaks in plasmid DNA. DHICA increases the activity and expression levels of SOD and Catalase. DHICA is applicable to research related to skin cancer and colon cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5,6-Dihydroxyindole-2-carboxylic acid. CAS No. 4790-8-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W018158.
DHICA
DHICA is an intermediate in melanin synthesis and a component of true black pigment. DHICA is a moderately potent GPR35 agonist and shows an ability to stimulate β-arrestin translocation signaling with an EC50 value of 23.2 μM in the U2OS cell line. Synonyms: 5,6-dihydroxyindole-2-carboxylic acid; DHI2C; 5,6-Dhica. CAS No. 4790-8-3. Molecular formula: C9H7NO4. Mole weight: 193.16.
D-His1-Liraglutide
An impurity of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used primarily to treat type 2 diabetes (T2D) and obesity. Synonyms: D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly; DHis-AEGTFTSDVSSYLEGQAA-Lys(Palm-γ-Glu)-EFIAWLVRGRG; D-Histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; [D-His1]-Liraglutide; [D-His]1-Liraglutide; D-His(1)-Liraglutide; Liraglutide D-His(1); D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(γ-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: ≥95%. Molecular formula: C172H265N43O51. Mole weight: 3751.26.
D-His(1)-Semaglutide
D-[His]-1-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 6; Semaglutide D-His-7 Impurity; D-His(7)-Semaglutide; D-[His]-1-Semaglutide; D-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grade: 95%. Molecular formula: C187H291N45O59. Mole weight: 4113.64.
D-His-endo-Ala18-Liraglutide
D-His-endo-Ala18-Liraglutide is a derivative of Liraglutide, a long-acting analog of glucagon-like peptide-1 (GLP-1) receptor which could protect b-cells from apoptosis under conditions associated with the development of type 1 and type 2 diabetes. Synonyms: H-D-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Ala-Lys(Gamma-Glu-palmitoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C175H270N44O52. Mole weight: 3822.36.
D-His-OMe 2HCl
D-Histidine methyl ester is a protected form of D-Histidine. D-Histidine is the unnatural, biologically inactive isomer of L-Histidine. D-histidine is known to inhibit cell division, and is also used by certain types of bacteria (such as Escherichia coli) as a source of L-Histidine. Synonyms: D-Histidine methyl ester dihydrochloride; (R)-methyl 2-amino-3-(1H-imidazol-4-yl)propanoate dihydrochloride; H-D-His-OMe 2HCl; D-HISTIDINE METHYLESTER DIHYDROCHLORIDE; H-D-His-OMe 2HCl; methyl (2R)-2-amino-3-(1H-imidazol-5-yl)propanoate dihydrochloride; H D His OMe 2HCl. Grade: ≥ 98% (HPLC). CAS No. 4467-54-3. Molecular formula: C7H11N3O2·2HCl. Mole weight: 242.11.
D-Histidine hydrochloride monohydrate. Group: Biochemicals. Alternative Names: D-His-OH·HCl·H2O. Grades: Highly Purified. CAS No. 6341-24-8. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
D-Histidine hydrochloride monohydrate
An unnatural isomer of histidine. Synonyms: D-Histidine monohydrochloride monohydrate; D-alpha-Amino-Beta-(4-imidazolyl)propionic acid monohydrochloride monohydrate. Grade: ≥ 98% (TLC). CAS No. 6341-24-8. Molecular formula: C6H10ClN3O2. Mole weight: 191.61.
D-Histidine hydrochloride monohydrate 99+%
D-Histidine hydrochloride monohydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 6341-24-8. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
D-Histidinol
D-Histidinol. CAS No. 70142-15-3. Molecular formula: C6H11N3O. Mole weight: 141.17.
DHMEQ racemate
DHMEQ racemate is an NF-κB inhibitor. The activity of DHMEQ racemate is lower than (-)-DHMEQ. Synonyms: Cis(+/-)-2-hydroxy-N-(2-hydroxy-5-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl)benzamide; rel-DHMEQ. CAS No. 287194-38-1. Molecular formula: C13H11NO5. Mole weight: 261.23.
DHODH-IN-1
DHODH-IN-1 is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor (IC50 = 25 nM), and also an inhibitor of pyrimidine biosynthesis pathway. Synonyms: 5-Cyclopropyl-2-[4-(2,6-difluorophenoxy)-3-isopropoxy-5-methyl-1H-pyrazol-1-yl]-3-fluoropyridine; Pyridine, 5-cyclopropyl-2-[4-(2,6-difluorophenoxy)-5-methyl-3-(1-methylethoxy)-1H-pyrazol-1-yl]-3-fluoro-; 2-[4-[2,6-bis(fluoranyl)phenoxy]-5-methyl-3-propan-2-yloxy-pyrazol-1-yl]-5-cyclopropyl-3-fluoranyl-pyridine; 2-(3-Isopropyloxy-4-(2,6-difluorophenoxy)-5-methyl-1H-pyrazole-1-yl)-3-fluoro-5-cyclopropylpyridine. Grade: ≥95%. CAS No. 1800296-63-2. Molecular formula: C21H20F3N3O2. Mole weight: 403.40.
DHODH-IN-12
DHODH-IN-12, a leflunomide derivative, is a weak inhibitor of dihydroorotate dehydrogenase (DHODH) with a pKa of 5.07. Synonyms: (2E)-2-cyano-2-(hydroxyimino)-N-(4-methylphenyl)ethanamide; Acetamide, 2-cyano-2-(hydroxyimino)-N-(4-methylphenyl)-, (2E)-. Grade: ≥95%. CAS No. 1263303-93-0. Molecular formula: C10H9N3O2. Mole weight: 203.20.
DHODH-IN-13
DHODH-IN-13, a hydroxyfurazan analogue of A771726, is an inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 4.3 μM for rat liver DHODH. It can be used for rheumatoid arthritis. Synonyms: 4-Oxo-N-[4-(trifluoromethyl)phenyl]-4,5-dihydro-1,2,5-oxadiazole-3-carboxamide; 1,2,5-Oxadiazole-3-carboxamide, 4,5-dihydro-4-oxo-N-[4-(trifluoromethyl)phenyl]-. Grade: ≥95%. CAS No. 1364791-86-5. Molecular formula: C10H6F3N3O3. Mole weight: 273.17.