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| Product | Description | |
|---|---|---|
| Gallium Nitride Substrates | Gallium Nitride Substrates. CAS No. 25617-97-4. Purity: >99.9%. |  |
| Gallium Nitride wafer | Gallium Nitride wafer. CAS No. 25617-97-4. Purity: >99.9%. | |
| Gallium Oxide | Gallium Oxide. CAS No. 12024-21-4. Molecular formula: Ga2O3. Mole weight: 187.444 g/mol. Purity: 99.9%. | |
| Gallium Oxide Doped Zinc Oxide (GZO) Sputtering Targets | Gallium Oxide Doped Zinc Oxide (GZO) Sputtering Targets. Alternative Names: Gallium Oxide Doped Zinc Oxide (GZO) Sputtering Targets, GZO Sputtering Target, GZO Sputter Target, GZO Target, Gallium Oxide Doped Zinc Oxide Sputtering Target, Gallium Oxide Doped Zinc Oxide Sputter Target, Gallium Oxide Doped Zinc Oxide Target. Purity: 99.9%. | |
| Gallium Oxide (Ga2O3) | Gallium Oxide (Ga2O3). Alternative Names: Gallium Oxide Powder, Ga2O3 Powder, digallium trioxide; gallium(III) oxide; gallium oxide. Purity: 99.999%, 99.9999%. | |
| Gallium Oxide (Ga2O3) Sputtering Targets | Gallium Oxide (Ga2O3) Sputtering Targets. Alternative Names: Gallium Oxide (Ga2O3) Sputtering Targets, Ga2O3 Sputtering Targets, Ga2O3 Targets, Ga2O3 Sputter Targets. Purity: 99.99%-99.9999%. | |
| Gallium Oxide Nanoparticle Dispersion | Gallium Oxide Nanoparticle Dispersion. Mole weight: 187.44. IUPAC Name: Digallium oxygen(2-). SMILES: O=[Ga]O[Ga]=O. InChI: InChI=1S/2Ga.3O. | |
| Gallium Oxide Nanoparticles / Nanopowder | Gallium Oxide Nanoparticles / Nanopowder. CAS No. 12024-21-4. Mole weight: 187.44. IUPAC Name: Digallium oxygen(2-). SMILES: O=[Ga]O[Ga]=O. InChI: InChI=1S/2Ga.3O. | |
| Gallium Oxide Nanopowder | Gallium Oxide Nanopowder. CAS No. 12024-21-4. Molecular formula: Ga2O3. Mole weight: 187.44 g/mol. Purity: 99.9%. | |
| GALLIUM PERCHLORATE HYDRATE 99.999% | GALLIUM PERCHLORATE HYDRATE 99.999%. Alternative Names: Gallium(III) perchlorate hydrate, 574090_ALDRICH, 81029-07-4. CAS No. 81029-07-4. Molecular formula: Cl3GaH2O13. Mole weight: 386.09008. Purity: 96%. IUPAC Name: gallium;triperchlorate;hydrate. SMILES: O.[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O.[Ga+3]. | |
| Gallium phosphide | Gallium phosphide. Alternative Names: Gallium monophosphide. CAS No. 12063-98-8. Molecular formula: GaP. Mole weight: 100.7. Purity: 96%. IUPAC Name: gallanylidynephosphane. SMILES: [P]#[Ga]. InChI: 1S/Ga.P. | |
| Gallium Phosphide | GALLIUM PHOSPHIDE, 99.999% pure, 6 mm pieces and smaller, Formula: GaP. CAS No. 12063-98-8. Noah Chemicals San Antonio, Texas. ISO 9001:2015 Certified. Request a Quote Today! |  Texas TX |
| Gallium phosphide, 99.99% metals basis | Gallium phosphide, 99.99% metals basis. CAS No. 12063-98-8. Molecular formula: GaP;GaP. Mole weight: 100.7g/mol. IUPAC Name: gallanylidynephosphane. SMILES: P#[Ga]. InChI: InChI=1S/Ga.P. | |
| Gallium Phosphide (GaP) Semiconductor Crystal | Gallium Phosphide (GaP) Semiconductor Crystal. Alternative Names: GaP Wafers, GaP Substrate, GaP Slice, Gallium Phosphide Wafers, Gallium Phosphide Substrate, Gallium Phosphide Slice. | |
| Gallium Phosphide Nanodispersion | Gallium Phosphide Nanodispersion. CAS No. 12063-98-8. Mole weight: 100.7. IUPAC Name: gallanylidynephosphane. SMILES: [Ga]>P. InChI: InChI=1S/Ga.P. | |
| Gallium selenide | Gallium selenide. Alternative Names: Gallium selenide;Gallium selenide (Ga2Se3, GaSe, 5N);Gallium sesquiselenide. CAS No. 12024-24-7. Molecular formula: Ga2Se3. Mole weight: 376.326. Purity: N/A. IUPAC Name: digallium selenium(2-). SMILES: [Ga+3].[Ga+3].[Se-2].[Se-2].[Se-2]. | |
| Gallium Selenide Ga2Se3 Powder | Gallium Selenide Ga2Se3 Powder. CAS No. 12024-24-7. Molecular formula: Ga2Se3. Mole weight: 376.33. Purity: 99.99%-99.9999%, or customized. | |
| Gallium Selenide (Ga2Se3) Sputtering Targets | Gallium Selenide (Ga2Se3) Sputtering Targets. Alternative Names: Gallium Selenide (Ga2Se3) Sputtering Targets, Ga2Se3 Sputtering Target, Ga2Se3 Sputter Target, Ga2Se3 Target, Gallium Selenide Sputtering Target, Gallium Selenide Sputter Target, Gallium Selenide Target. Purity: 99.999%. | |
| Gallium Sulfide Ga2S3 Powder | Gallium Sulfide Ga2S3 Powder. CAS No. 12024-22-5. Molecular formula: Ga2S3. Mole weight: 235.64. Purity: 99.999% or customized. | |
| Gallium Sulfide (GaS) | Gallium Sulfide (GaS). Alternative Names: Gallium Sulfide Powder, GaS Powder, gallium sulphide; gallium(II) sulphide; gallium sulfide; gallium(II) sulfide. Purity: 99.999%. | |
| Gallium Sulfide (GaS) Sputtering Targets | Gallium Sulfide (GaS) Sputtering Targets. Alternative Names: Gallium Sulfide (GaS) Sputtering Targets, GaS Sputtering Targets, GaS Targets, GaS Sputter Targets. Purity: 99.999%. | |
| Gallium Telluride | Gallium Telluride. Grades: 99.999% Extremely High (>=99%). CAS No. 12024-14-5. Pack Sizes: Gram Quantities: 5 gm, 10 gm. Order Number: 1903. |  www.prochemonline.com |
| Gallium Telluride (Ga2Te3) | Gallium Telluride (Ga2Te3). Alternative Names: Gallium Telluride Powder, Ga2Te3 Powder, Gallium Telluride, Ga2Te3, 12024-27-0. Purity: 99.99%, 99.999%, 99.9999%. | |
| Gallium Telluride (Ga2Te3) Sputtering Targets | Gallium Telluride (Ga2Te3) Sputtering Targets. Alternative Names: Gallium Telluride (Ga2Te3) Sputtering Targets, Ga2Te3 Sputtering Target, Ga2Te3 Sputter Target, Ga2Te3 Target, Gallium Telluride Sputtering Target, Gallium Telluride Sputter Target, Gallium Telluride Target. Purity: 99.9%-99.999%. | |
| Gallium Telluride (GaTe) | Gallium Telluride (GaTe). Alternative Names: Gallium Telluride Powder, GaTe Powder, gallium telluride; gallium(II) telluride. Purity: 99.999%. | |
| Gallium Tin alloy, 99.99% (metals basis) | Gallium Tin alloy, 99.99% (metals basis). | |
| Gallium trihydroxide | Gallium trihydroxide. Alternative Names: Gallium trihydroxide, Gallium(+3) Cation Trihydroxide, EINECS 234-687-5, CID10154045, 12023-99-3. CAS No. 12023-99-3. Purity: 96%. Product ID: ACM12023993. Molecular formula: GaH3O3. Mole weight: 120.745020 [g/mol]. IUPAC Name: gallium trihydroxide. ECNumber: 234-687-5. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Gallocatechin | Gallocatechin isolated from the wood of Acacia catechu (L.F.) Willd. It possesses free radical scavenging ability and has moderate affinity to the human cannabinoid receptor. Uses: Antioxidant. Alternative Names: 2α-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3β,5,7-triol;(2S)-2β-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3α,5,7-triol;(2S)-3,4-Dihydro-2β-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3α,5,7-triol. Grades: 98%. CAS No. 970-73-0. Molecular formula: C15H14O7. Mole weight: 306.27. |  |
| GALLOCATECHIN | GALLOCATECHIN. CAS No. 3371-27-5. Purity: 0.999. Product ID: DS3371275. Mole weight: 306.27. ECNumber: 608-899-7. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gallocatechin gallate | Gallocatechin gallate is a Flavonoids product that can be isolated from the herbs of Celastrus orbiculatus[1]. Uses: Scientific research. Category: Natural products. CAS No. 5127-64-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7727. |  |
| GALLOCATECHIN GALLATE | GALLOCATECHIN GALLATE. CAS No. 4233-96-9. Product ID: DS4233969. Mole weight: 458.37. ECNumber: 636-979-1. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Gallocatechin gallate (GCG) | Gallocatechin gallate (GCG). Group: Biochemicals. Alternative Names: (-)-Gallocatechin gallate; GCG. Grades: Plant Grade. CAS No. 4233-96-9. Pack Sizes: 20mg. Molecular Formula: C22H18O11, Molecular Weight: 458.372. US Biological Life Sciences. |  Worldwide |
| Gallocyanine | Gallocyanine. Group: Biochemicals. Alternative Names: Mordant Blue 1; CI 513; 7-Dimethylamino-4-hydroxy-3-oxo-3H-phenoxazine-1-carboxylic acid. Grades: Highly Purified. CAS No. 1562-85-2. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| Galloflavin | Galloflavin. Group: Biochemicals. Alternative Names: 3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione; NSC 107022. Grades: Highly Purified. CAS No. 568-80-9. Pack Sizes: 10mg. Molecular Formula: C12H6O8, Molecular Weight: 278.17. US Biological Life Sciences. | Worldwide |
| Galloflavin | Galloflavin is a potent lactate dehydrogenase (LDH) inhibitor. The calculated Kis for pyruvate are 5.46 μM (LDH-A) and 15.06 μM (LDH-B). Galloflavin hinders the proliferation of cancer cells by blocking glycolysis and ATP production[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 568-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W040118. | |
| Galloflavin | Galloflavin is a novel inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 μM, respectively). It has also been shown to be a potential anticancer agent. Alternative Names: NSC 107022; 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione. Grades: ≥98%. CAS No. 568-80-9. Molecular formula: C12H6O8. Mole weight: 278.2. | |
| Galloylpaeoniflorin | 6'-O-Galloylpaeoniflorin is a natural monoterpenoid compound isolated from the roots of Paeonia lactiflora Pall. 6'-O-Galloylpaeoniflorin exhibits strong androgen receptor (AR) binding activity. Alternative Names: β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate); β-D-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-(3,4,5-trihydroxybenzoate), [1aR-(1aα,2β,3aα,5α,5aα,5bα)]-; 6'-O-Galloyl paeoniflorin; ((2R,3S,4S,5R,6S)-6-(((1aR,1a1S,2R,3aR,5S,5aR)-1a1-((Benzoyloxy)methyl)-2-hydroxy-5-methyltetrahydro-1H-3,4-dioxa-2,5-methanocyclobuta[cd]pentalen-5a(5H)-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl 3,4,5-trihydroxybenzoate. Grades: >98%. CAS No. 122965-41-7. Molecular formula: C30H32O15. Mole weight: 632.57. | |
| Galloylpaeoniflorin | Galloylpaeoniflorin. Group: Biochemicals. CAS No. 122965-41-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Galloylpaeoniflorin | Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6'-O-Galloyl paeoniflorin. CAS No. 122965-41-7. Pack Sizes: 5 mg. Product ID: HY-N5048. | |
| GalNAc5-diNAcBac-PP-undecaprenol β-1,3-glucosyltransferase | Isolated from the bacterium Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. |  |
| GalNAc5-diNAcBac-PP-undecaprenol β-1,3-glucosyltransferase | Isolated from the bacterium Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. Group: Enzymes. Synonyms: PglI. Enzyme Commission Number: EC 2.4.1.293. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2527; GalNAc5-diNAcBac-PP-undecaprenol β-1,3-glucosyltransferase; EC 2.4.1.293; PglI. Cat No: EXWM-2527. | |
| GalNAc-α-(1?4)-GalNAc-α-(1?3)-diNAcBac-PP-undecaprenol α-1,4-N-acetyl-D-galactosaminyltransferase | Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. | |
| GalNAc-α-(1?4)-GalNAc-α-(1?3)-diNAcBac-PP-undecaprenol α-1,4-N-acetyl-D-galactosaminyltransferase | Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway. Group: Enzymes. Synonyms: PglH. Enzyme Commission Number: EC 2.4.1.292. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2526; GalNAc-α-(1?4)-GalNAc-α-(1?3)-diNAcBac-PP-undecaprenol α-1,4-N-acetyl-D-galactosaminyltransferase; EC 2.4.1.292; PglH. Cat No: EXWM-2526. | |
| GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP | GalNAcb(1-3)Gala(1-3)Galb(1-4)Glc-b-pNP is a crucial compound extensively used in the biomedical industry for studying glycosidase-related diseases. It acts as a substrate for enzymes involved in research of lysosomal storage disorders such as Tay-Sachs disease and Gaucher disease. Molecular formula: C32H48N20O23. Mole weight: 1080.84. | |
| GalNAc-b-1-4-Gal-b-1-4-Glc-b-ethylazide | GalNAc-b-1-4-Gal-b-1-4-Glc-b-ethylazide. | |
| GalNAc C3 CPG | GalNAc-C3-CPG, a novel therapeutic agent, holds significant potential in the fight against viral infections. Its innovative and intricate architecture aptly mimics viral RNA, thereby facilitating the activation of the immune system and a consequential robust antiviral response. Alternative Names: GalNAc C3 CPG 1000Å; (4-(Trimethoxytrityloxymethyl)-1-(6-(4-(3,4,6-O-triacetyl-2-acetylamino-2-deoxy-β-D-galactopyranosyl)butanamido)hexanoyl)piperidin-4-yl)methyl-O-succinoyl CPG. | |
| GalNAc-Cluster-COOH | GalNAc-Cluster-COOH is a functionalized ligand designed for targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc (N-acetylgalactosamine) cluster linked to a PEG spacer and terminated with a carboxylic acid group, which facilitates conjugation to other molecules. This compound is widely used in the development of lysosome-targeting chimeras (LYTACs) and for delivering nucleic acids or protein complexes to liver cells in a cell-specific manner. Its structure and valency enhance binding affinity to ASGPR, enabling efficient internalization and delivery of therapeutic agents. Alternative Names: N2,N6-Bis[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysyl-N6-[2-[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetyl]-L-lysine; (17S,20S)-1-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-20-(1-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-11-oxo-3,6,9-trioxa-12-azahexadecan-16-yl)-17-(2-(2-(2-(2-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)acetamido)-11,18-dioxo-3,6,9-trioxa-12,19-diazahenicosan-21-oic acid. Grades: >98%. CAS No. 1332358-22-1. Molecular formula: C60H107N7O33. Mole weight: 1454.52. | |
| Galnac GLS-15 | GalNAc GLS-15 is a novel GalNAc-derived small molecule structure designed for siRNA delivery. It is engineered to leverage the high affinity of GalNAc for the asialoglycoprotein receptor (ASGPR) on hepatocytes, enabling efficient liver-targeted delivery of siRNA molecules. This compound is part of the broader GalNAc delivery system, which has been widely adopted for RNA interference (RNAi) therapies due to its ability to enhance drug uptake and reduce off-target effects. Alternative Names: GLS15; GalNAc GLS-15. Grades: >98%. CAS No. 2920438-06-6. Molecular formula: C82H132N11O37P. Mole weight: 1894.97. | |
| GalNAc-hexyl-threoninol-CPG | GalNAc-hexyl-threoninol-CPG is a solid-supported GalNAc (N-acetylgalactosamine) monomer designed for the efficient synthesis of GalNAc-conjugated oligonucleotides. It features a GalNAc moiety attached to a threoninol scaffold via a hexyl linker, with the primary hydroxyl group protected by a dimethoxytrityl (DMT) group. The compound is immobilized on a solid support (controlled-pore glass, CPG) through a succinylated linker, facilitating its use in solid-phase synthesis. This configuration allows for the convenient and scalable incorporation of GalNAc units into oligonucleotides, enhancing their targeting efficiency to hepatocytes via the asialoglycoprotein receptor (ASGPR). GalNAc-hexyl-threoninol-CPG serves as a versatile building block for developing targeted nucleic acid therapeutics with improved cellular uptake and specificity. | |
| GalNAc-INF7 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Alternative Names: GalNAc-CGLFEAIEGFIENGWEGMIDGWYG. Molecular formula: C189H303N39O70S2. Mole weight: 4305.78. | |
| GalNAc-L96-Amide | GalNAc-L96-Amide is a specialized compound within the GalNAc series, designed for targeted delivery of nucleic acid drugs to hepatocytes. This molecule features a triantennary GalNAc (N-acetylgalactosamine) core linked to a longer PEG-based linker and terminated with an amide group. The GalNAc core serves as a high-affinity ligand for the asialoglycoprotein receptor (ASGPR), which is highly expressed on hepatocytes, enabling efficient liver-targeted delivery. The compound is used primarily for the synthesis of GalNAc-siRNA conjugates, which leverage the ASGPR pathway to enhance the uptake and efficacy of siRNA molecules in the liver. This targeted delivery system avoids the immunogenicity associated with lipid-based delivery methods and improves the safety and specificity of nucleic acid therapies. GalNAc-L96-Amide is also a key intermediate in the development of advanced drug delivery systems, particularly for RNA interference (RNAi) therapies. Grades: >98%. | |
| GalNac-L96 analog | GalNAc-L96 analog is an intermediate used in the synthesis of ligands targeting the asialoglycoprotein receptor (ASGPR), a receptor highly expressed on hepatocytes and involved in the internalization and degradation of desialylated glycoproteins. It features a triantennary GalNAc (N-acetylgalactosamine) structure designed to enhance the targeting and delivery of nucleic acid drugs to liver cells. It is commonly used in the development of GalNAc-siRNA conjugates, which leverage the high affinity of GalNAc for ASGPR to facilitate efficient cellular uptake and endosomal release of siRNA molecules, thereby improving the efficacy of RNA-based therapies. Alternative Names: N-Acetylgalactosamine-L96 analog; GalNAc-L96; N-acetyl-D-Galactosamine-L96 analog; (2S,4R)-2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-hydroxy-λ-oxo-N-[2-[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]-1,1-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]ethyl]-1-pyrrolidinedodecanamide. Grades: ≥95%. CAS No. 1159408-72-6. Molecular formula: C117H175N11O42. Mole weight: 2407.69. | |
| GalNAc-L96-CPG | GalNAc-L96-CPG is a solid support reagent designed for the synthesis of GalNAc-conjugated oligonucleotides, particularly siRNA, for targeted delivery applications. It consists of a triantennary GalNAc ligand (specifically the L96 variant) covalently attached to a controlled pore glass (CPG) support via a linker. The GalNAc moiety serves as a high-affinity ligand for the asialoglycoprotein receptor (ASGPR), which is abundantly expressed on hepatocytes, enabling efficient receptor-mediated endocytosis of the conjugated oligonucleotide into liver cells. This system facilitates the development of RNA interference (RNAi) therapeutics, such as GalNAc-siRNA conjugates, by enhancing cellular uptake and pharmacokinetic properties. Alternative Names: 3'-GalNAc CPG 1000; GalNAc-L96 CPG. | |
| GalNac-L96 free base | GalNAC-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Alternative Names: L-96; Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester; 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate; GalNAc-L96-SA; L-96-Succinic Acid; GalNAc-L96-Succinate. Grades: 98%. CAS No. 1159408-61-3. Molecular formula: C121H179N11O45. Mole weight: 2507.76. | |
| GalNAc-L96 Linker-Acid | GalNAc-L96 Linker-Acid is a specialized chemical compound designed for the synthesis of targeted nucleic acid delivery systems. It features a triantennary GalNAc (N-acetylgalactosamine) cluster linked to a longer PEG-based linker, terminating with a carboxylic acid group. This structure allows for efficient conjugation to oligonucleotides, such as siRNA, enabling targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). The compound is widely used in the development of RNA interference (RNAi) therapies, particularly for liver-related diseases. This linker is a key intermediate in the synthesis of GalNAc-siRNA conjugates, which have demonstrated superior stability and gene silencing efficiency compared to traditional lipid nanoparticle delivery systems. Alternative Names: 12,19,25-Trioxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacosanoic acid; 1-(((2R,3R,4R,5R,6R)-3-Acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-16,16-bis((3-((3-(5-(((2R,3R,4. Grades: ≥97%. CAS No. 1426159-34-3. Molecular formula: C91H148N10O39. Mole weight: 2006.22. | |
| GalNAc-L96 Linker-Azide | GalNAc-L96 Linker-Azide is a specialized chemical compound designed for the development of targeted nucleic acid delivery systems. It features a triantennary GalNAc (N-acetylgalactosamine) cluster linked to a PEG-based linker, terminating with an azide group. This structure allows for efficient conjugation to oligonucleotides or other therapeutic agents through click chemistry, enabling targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). GalNAc-L96 Linker-Azide is particularly useful in the synthesis of GalNAc-siRNA conjugates, which have demonstrated high efficiency in liver-targeted gene silencing. The azide group provides a convenient handle for conjugation, making it suitable for the development of advanced drug delivery systems, especially for RNA interference (RNAi) therapies. Grades: ≥97%. CAS No. 2135330-72-0. Molecular formula: C90H147N13O37. Mole weight: 2003.22. | |
| GalNac-L96 (triethylamine salt) | GalNAC-L96 is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Alternative Names: L96.TEA; N-Acetylgalactosamine-L96 triethylamine salt; N-acetyl-D-Galactosamine-L96 triethylamine salt. Grades: ≥98%. CAS No. 1159408-62-4. Molecular formula: C127H194N12O45. Mole weight: 2608.95. | |
| GalNAc-Lipid GL3 | GalNAc-Lipid GL3 is a first-generation GalNAc-based ligand designed for targeted delivery of therapeutic agents to hepatocytes via the asialoglycoprotein receptor (ASGPR). It features a trivalent GalNAc structure attached to a TRIS scaffold, which facilitates efficient binding to ASGPR and subsequent cellular uptake. In preclinical studies, GalNAc-Lipid GL3 was formulated into lipid nanoparticles (LNPs) and tested for its ability to deliver CRISPR base editors to the liver. While effective, GL3 demonstrated lower editing efficiency compared to its second-generation counterpart, GalNAc-Lipid GL6, which achieved higher liver editing rates in both LDLR-deficient and wild-type mice. This suggests that GL3's TRIS scaffold may be less optimal than the lysine-based scaffold used in GL6 for ASGPR-mediated uptake and delivery. Despite this, GalNAc-Lipid GL3 remains an important reference in the development of targeted liver delivery systems, highlighting the potential of GalNAc ligands for non-LDLR-dependent therapies. Grades: >98%. | |
| GalNAc-Lipid GL5 | GalNAc-Lipid GL5 is a targeting ligand designed for lipid nanoparticles (LNPs) with a short 12-unit PEG linker. It enables non-LDLR (low-density lipoprotein receptor)-dependent delivery of therapeutic agents to hepatocytes. However, compared to GL6 with a longer PEG linker, GL5 exhibits lower liver-targeting efficiency. For instance, in experiments targeting the _Angptl3_ gene in mice, GL5 achieved only 18% liver editing efficiency, while GL6 reached 56%. This suggests that the shorter PEG linker in GL5 may limit its binding affinity to ASGPR (asialoglycoprotein receptor) on hepatocytes. Despite its lower efficiency, GL5 remains valuable for understanding the structure-function relationship in GalNAc-LNP design. Grades: ≥98%. | |
| GalNAc-Lipid GL6 | GalNAc-Lipid GL6 is a potent and scalable ligand designed for targeted liver delivery of therapeutic agents, particularly in the context of CRISPR base editing therapies. It features a multi-valent N-acetylgalactosamine (GalNAc) structure that binds specifically to the asialoglycoprotein receptor (ASGPR), enabling efficient uptake by hepatocytes. This ligand is part of the second-generation GalNAc design, which incorporates a lysine-based scaffold and a longer PEG spacer (34-38 units) compared to earlier designs. The combination of a 1,2-O-dioctadecyl-sn-glyceryl (DSG) lipid anchor and the optimized PEG spacer enhances the stability and delivery efficiency of lipid nanoparticles (LNPs) in vivo. In preclinical studies, GalNAc-Lipid GL6 demonstrated superior performance in liver-targeted gene editing compared to other GalNAc ligands, achieving high editing rates in both wild-type and LDLR-deficient mice and non-human primates. This ligand has shown significant potential for non-LDLR-dependent delivery of CRISPR therapies, making it a valuable tool for treating genetic disorders and metabolic diseases. Grades: 98%. | |
| GalNAc-Lipid GL7 | GalNAc-Lipid GL7 is a ligand designed to optimize the delivery of lipid nanoparticles (LNPs) to hepatocytes via non-LDLR (low-density lipoprotein receptor) dependent pathways. It is based on Design 2, which features a lysine scaffold with three GalNAc units attached through a 36-unit PEG linker. The primary goal of GL7 is to evaluate the impact of different lipid anchors on the stability and delivery efficiency of LNPs. Specifically, GL7 incorporates a cholesteryl (Chol) lipid anchor, which was tested alongside other lipid anchors like 1,2-O-dioctadecyl-sn-glyceryl (DSG) and arachidoyl (C20) to assess their effects on ASGPR (asialoglycoprotein receptor) recognition and binding. However, experiments in Ldlr-mice demonstrated that the DSG lipid anchor in GL6 was significantly more effective for liver-targeted gene editing compared to the cholesterol anchor in GL7, with an editing efficiency of 56% for DSG versus 4% for cholesterol. This suggests that GL7, with its cholesterol anchor, is less efficient for non-LDLR-dependent delivery of LNPs to hepatocytes. Grades: ≥98%. | |
| GalNAc-Lipid GL9 | GalNAc-Lipid GL9 is a ligand designed for lipid nanoparticles (LNPs) to facilitate non-LDLR (low-density lipoprotein receptor)-dependent delivery of therapeutic agents to hepatocytes. It is based on Design 2, which uses a lysine scaffold with three GalNAc units attached through a PEG linker. The primary goal of GL9 is to evaluate the impact of different lipid anchors on the stability and delivery efficiency of LNPs. In GL9, the lipid anchor is an arachidoyl (C20) moiety, which was tested alongside other lipid anchors like 1,2-O-dioctadecyl-sn-glyceryl (DSG) and cholesterol (Chol) to assess their effects on ASGPR (asialoglycoprotein receptor) recognition and binding. However, experiments in LDLR-deficient mice demonstrated that the DSG lipid anchor in GL6 was significantly more effective for liver-targeted gene editing compared to the arachidoyl (C20) anchor in GL9. Specifically, the editing efficiency of GL6 with DSG was 56%, while GL9 with C20 achieved only 8% efficiency. This indicates that GL9, with its C20 lipid anchor, is less efficient for non-LDLR-dependent delivery of LNPs to hepatocytes. Grades: ≥98%. | |
| GalNAc-NAG-25 Phosphoramidite | GalNAc-NAG-25 Phosphoramidite is a modified phosphoramidite that incorporates a N-acetylgalactosamine (GalNAc) moiety linked to the NAG component, specifically designed for the synthesis of oligonucleotides. This compound enhances the stability and bioactivity of nucleic acids, particularly in applications involving targeted delivery and therapeutic interventions. Its unique structural features allow for improved interactions with cellular receptors, making GalNAc-NAG-25 Phosphoramidite valuable in the development of glyco-engineered therapeutics and in the field of glycobiology, where carbohydrate-based modifications play a crucial role in biological processes. Alternative Names: NAG-25; NAG 25; NAG25; GalNAc NAG-25 Phosphoramidite; N2-[23-[Bis(1-methylethyl)amino]-26-cyano-1-oxo-4,7,10,13,16,19,22,24-octaoxa-23-phosphahexacos-1-yl]-N-[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-γ-glutamyl-N,N2-bis[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-glutamamide. Grades: ≥95%. CAS No. 2130036-52-9. Molecular formula: C88H145N10O43P. Mole weight: 2062.13. | |
| GalNAc-NAG37 phosphoramidite | GalNAc-NAG37 phosphoramidite is an N-acetylgalactosamine (GalNAc) derivative that acts as a ligand for the asialoglycoprotein receptor (ASGPR). GalNAc-NAG37 phosphoramidite can be used to synthesize GalNAc-siRNA and for oligonucleotide delivery[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2199491-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-173247. | |
| GalNAc-PEG-Cluster-1-CPG | GalNAc-PEG-Cluster-1-CPG is a specialized reagent used for the synthesis of oligonucleotide conjugates, particularly for liver-targeted drug delivery. It combines N-acetylgalactosamine (GalNAc) with a polyethylene glycol (PEG) linker and a controlled pore glass (CPG) support to facilitate the attachment of GalNAc clusters to oligonucleotides. This structure enhances the targeting of siRNA or other nucleic acid drugs to hepatocytes via the asialoglycoprotein receptor (ASGPR), improving cellular uptake and therapeutic efficacy. Grades: ≥98%. | |
| GalNAc(TEG)-CPG | GalNAc CPG allows the synthesis of siRNA-GalNAc conjugate. | |
| GalNAc trimer-Cy5.5 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. Cy5.5 (Cyanine-5.5) is a cyanine dye. Alternative Names: GalNAc trimer-Cyanine5.5. Molecular formula: C112H172N13O33. Mole weight: 2228.63. | |
| Galnon | Galnon. Group: Biochemicals. Grades: Purified. CAS No. 475115-35-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Galnon | Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Alternative Names: 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide; L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Fmoc-b-cyclohexyl-Ala-Lys-AMC. Grades: ≥95% by HPLC. CAS No. 475115-35-6. Molecular formula: C40H46N4O6. Mole weight: 678.83. | |
| Galunisertib | Galunisertib Inhibitor. Uses: Scientific use. Product Category: T2510. CAS No. 700874-72-2. |  |
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