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| Product | Description | |
|---|---|---|
| HCTU | Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. |  Luxembourg Bio Technologies |
| HCTU | HCTU. Group: Biochemicals. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N,N,N',N'-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate; 1-[Bis (dimethylamino) methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate. Grades: Highly Purified. CAS No. 330645-87-9. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C11H15ClF6N5OP. US Biological Life Sciences. |  Worldwide |
| HCTU | HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g; 250 g; 500 g; 1000 g. Product ID: HY-W010951. |  |
| HCV371 | HCV371 is a potent and selective HCV NS5B polymerase inhibitor. It binds the NS5B with an apparent dissociation constant of 150 nM, which leads to high selectivity and lack of cytotoxicity in the antiviral assays. It displayed broad inhibitory activities against the NS5B RdRp enzyme. It showed no inhibitory activity against a panel of human polymerases, including mitochondrial DNA polymerase gamma and other unrelated viral polymerases. Synonyms: HCV-371; HCV 371; HCV371. (R)-2-(5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid. Grade: 98%. CAS No. 675184-27-7. Molecular formula: C18H20N2O3. Mole weight: 312.37. |  |
| HCV-IN-29 | HCV-IN-29 is an inhibitor of hepatitis C virus (HCV). (Exacted from patent US8329159B2, compound 1e). Synonyms: 4,4'-Bis(2-((S)-pyrrolidin-2-yl)-1H-imidazol-5-yl)-1,1'-biphenyl tetrahydrochloride; 5,5'-[1,1'-Biphenyl]-4,4'-diylbis[2-(2S)-2-pyrrolidinyl-1H-imidazole] Hydrochloride; 5,5'-(4,4'-Biphenyldiyl)bis{2-[(2S)-2-pyrrolidinyl]-1H-imidazole} tetrahydrochloride. Grade: ≥98% (HPLC). CAS No. 1009119-83-8. Molecular formula: C26H32Cl4N6. Mole weight: 570.38. | |
| HCV-IN-3 | HCV-IN-3 is an inhibitor of hepatitis C virus (HCV) NS3/4a protein, with an IC50 of 20 μM and a Kd of 29 μM. Synonyms: 2,4-Difluoro-3-phenoxybenzenemethaneamine; Benzenemethanamine, 2,4-difluoro-3-phenoxy-; 1-(2,4-Difluoro-3-phenoxyphenyl)methanamine. Grade: ≥95%. CAS No. 1401839-25-5. Molecular formula: C13H11F2NO. Mole weight: 235.23. | |
| HCV-IN-30 | HCV-IN-30 is an inhibitor of HCV NS5A replication complex with IC50s of 901 and 102 nM against genotypes 1a and 1b replicons, respectively. Synonyms: (2S,2'S)-Di-tert-butyl 2,2'-(5,5'-([1,1'-biphenyl]-4,4'-diyl)bis(1H-imidazole-5,2-diyl))bis(pyrrolidine-1-carboxylate); Bis(2-methyl-2-propanyl) (2S,2'S)-2,2'-[4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl)]di(1-pyrrolidinecarboxylate); (2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-1-pyrrolidinecarboxylic acid 1,1'-bis(1,1-dimethylethyl) ester; 1-Pyrrolidinecarboxylic acid, 2,2'-([1,1'-biphenyl]-4,4'-diyldi-1H-imidazole-5,2-diyl)bis-, 1,1'-bis(1,1-dimethylethyl) ester, (2S,2'S)-. Grade: ≥98% (HPLC). CAS No. 1007882-23-6. Molecular formula: C36H44N6O4. Mole weight: 624.77. | |
| HCV-IN-31 | HCV-IN-31 is an inhibitor of HCV, with an EC50/EC95 of 15.7 μM for HCV replicon. Synonyms: (2R,3R,4R,5R)-5-(2-amino-6-(methylamino)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; Adenosine, 2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-, (2'R)-; 2-Amino-2'-deoxy-2'-fluoro-N,2'-dimethyladenosine. Grade: ≥95%. CAS No. 1998705-62-6. Molecular formula: C12H17FN6O3. Mole weight: 312.30. | |
| HCV-IN-4 | HCV-IN-4 is a potent and orally bioactive HCV NS5A inhibitor, displaying great potency against GT1a, GT2b, GT3a, GT1a Y93H and GT1a L31V, with EC90s values of 3 pM, 0.3 nM, 0.01 nM, 0.5 nM and 0.02 nM, respectively. Synonyms: HCV-IN-4|CHEMBL3980210|HY-P0162|CS-0020242. Grade: ≥98% (HPLC). CAS No. 2058080-25-2. Molecular formula: C52H58FN9O8. Mole weight: 956.07. | |
| HCV-IN-7 | HCV-IN-7, a potent and orally active pan-genotypic HCV NS5A inhibitor (IC50 of 3-47 pM) with antiviral activity, demonstrates superior pan-genotypic profile and good pharmacokinetic characteristics, as well as favorable liver uptake. Synonyms: Methyl [(2S)-1-{(2S)-2-[5-(2-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-pyrrolidinyl]-1H-imidazol-5-yl}naphtho[1,2-b]thiophen-7-yl)-1H-imidazol-2-yl]-1-pyrrolidinyl}-3-methyl-1-oxo-2-butanyl]carbamate; Carbamic acid, N,N'-[naphtho[1,2-b]thiene-2,7-diylbis[1H-imidazole-5,2-diyl(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, dimethyl ester. Grade: ≥95%. CAS No. 1449756-86-8. Molecular formula: C40H48N8O6S. Mole weight: 768.92. | |
| HCV-IN-7 dihydrochloride | HCV-IN-7 hydrochloride, a potent and orally active pan-genotypic HCV NS5A inhibitor (IC50 of 3-47 pM) with antiviral activity, demonstrates superior pan-genotypic profile and good pharmacokinetic characteristics, as well as favorable liver uptake. Synonyms: Methyl [(2S)-1-{(2S)-2-[5-(2-{2-[(2S)-1-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-2-pyrrolidinyl]-1H-imidazol-5-yl}naphtho[1,2-b]thiophen-7-yl)-1H-imidazol-2-yl]-1-pyrrolidinyl}-3-methyl-1-oxo-2-butanyl]carbamate dihydrochloride; Carbamic acid, N,N'-[naphtho[1,2-b]thiene-2,7-diylbis[1H-imidazole-5,2-diyl(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, dimethyl ester, hydrochloride (1:2). Grade: ≥95%. CAS No. 1449756-87-9. Molecular formula: C40H50Cl2N8O6S. Mole weight: 841.85. | |
| HCVP-IN-1 | HCVP-IN-1 is an inhibitor of hepatitis C viral polymerase (HCVP). Synonyms: Pf-868554; 2-[4-(2-{(2R)-2-Cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl}ethyl)-2-fluorophenyl]-2-methylpropanenitrile; Benzeneacetonitrile, 4-[2-[(2R)-2-cyclopentyl-5-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-3,6-dihydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-2-fluoro-α,α-dimethyl-; (R)-2-(4-(2-(2-cyclopentyl-5-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-2-fluorophenyl)-2-methylpropanenitrile. Grade: 95%. CAS No. 877225-09-7. Molecular formula: C30H34FN5O3. Mole weight: 531.62. | |
| hCYP3A4 Fluorogenic substrate 1 | hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an Km value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 186299-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155002. | |
| H-Cys(4-methoxytrityl)-2-chlorotrityl resin | H-Cys(4-methoxytrityl)-2-chlorotrityl resin. Synonyms: H-Cys(Mmt)-2-ClTrt resin. | |
| H-Cys(Acm)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Cys(Acm)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: S-acetamidomethyl-L-cysteine-2-chlorotrityl resin. |  |
| H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH | H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH. Synonyms: H-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH. CAS No. 166184-23-2. Molecular formula: C41H61N13O15S2. Mole weight: 1040.15. | |
| H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2 | H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-NH2. Synonyms: Cdpgyigsr-NH2; Laminin peptide 11; Cystinyl-aspartyl-prolyl-glycyl-tyrosyl-isoleucyl-glycyl-seryl-arginyl-NH2; Laminin β-1 Chain (925-933) amide (human, mouse). CAS No. 110590-61-9. Molecular formula: C40H63N13O13S. Mole weight: 966.07. | |
| H-Cys(CH3Bzl)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(CH3Bzl)-Trt(2-Cl)-Resin; H-Cys(CH3Bzl)-Barlos Resin; S-(4-Methylbenzyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cys(Et)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(Et)-Trt(2-Cl)-Resin; H-Cys(Et)-Barlos Resin; S-Ethyl-L-cysteine 2-chlorotrityl resin. | |
| H-Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys-OH | H-Cys-Gly-Arg-Arg-Ala-Gly-Gly-Ser-Cys-OH. Molecular formula: C30H55N15O11S2. Mole weight: 865.98. | |
| H-Cys(MeOBzl)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(MeOBzl)-Trt(2-Cl)-Resin; H-Cys(MeOBzl)-Barlos Resin; S-(4-Methoxybenzyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cys(Npys)-D-Ala-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2 | H-Cys(Npys)-D-Ala-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2. Synonyms: Cys(Npys)-Ala-(D-Arg)9; D-Argininamide, 3-[(3-nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-; 3-[(3-Nitro-2-pyridinyl)dithio]-L-alanyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-arginyl-D-argininamide. Grade: ≥95%. CAS No. 1676104-79-2. Molecular formula: C65H123N41O13S2. Mole weight: 1751.07. | |
| H-Cys(tBu)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Cys(tBu)-Trt(2-Cl)-Resin; H-Cys(tBu)-Barlos Resin; S-(t-Butyl)-L-cysteine 2-chlorotrityl resin. | |
| H-Cysteamine-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: 2-Aminoethanethiol-2-chlorotrityl resin. | |
| H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH (Disulfide bond) | It is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: CTTHWGFTLC, CYCLIC; L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide; MMP-2/MMP-9 Inhibitor III; Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor III. Grade: ≥90%. CAS No. 244082-19-7. Molecular formula: C52H71N13O14S2. Mole weight: 1166.33. | |
| H-Cys(Trt)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Cys(Trt)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: S-Trityl-L-cysteine-2-chlorotrityl resin. | |
| HD2EODA | HD2EODA. Mole weight: 314. | |
| H-D-2-Nal-OH HCl | H-D-2-Nal-OH HCl. Synonyms: 3-(2-Naphthyl)-D-alanine hydrochloride; (R)-2-Amino-3-(naphthalen-2-yl)propanoic acid hydrochloride. Grade: 95%. CAS No. 122745-11-3. Molecular formula: C13H13NO2·HCl. Mole weight: 251.8. | |
| HD36 High Quality Foam | Our HD36 High-Quality foam offers superior performance, cushioning, and comfort, all at an affordable price. This high-quality, high-density foam provides medium support for more vigorously used products like couch and chair seating cushions, while still providing softness and comfort. This material is one of our most popular upholstery foams, and can also be used in body wedges, pet beds, and as packaging inserts. | |
| HD36 Regular Foam | This high-density foam provides firmness for more vigorously used products like couch, bench and chair seating cushions, while still offering softness and comfort. Its increased density provides more support in mattresses for those who desire it, and allows it to be used as comfort body wedges, beds for your favorite pet and in packaging. | |
| H-D-3-Pal-OH 2HCl | H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoic acid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grade: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10. | |
| HDA | HDA. Mole weight: 296. | |
| H-D-Abu-OtBu | H-D-Abu-OtBu. Synonyms: (R)-tert-Butyl 2-Aminobutanoate; (2R)-2-aminobutyric acid tert-butyl ester; D-2-Aminobutyric acid tert-butyl ester; 2-Methyl-2-propanyl (2R)-2-aminobutanoate; Butanoic acid, 2-amino-, 1,1-dimethylethyl ester, (2R)-; D-α-Aminobutyric acid t-butyl ester. Grade: 95%. CAS No. 313994-32-0. Molecular formula: C8H17NO2. Mole weight: 159.23. | |
| HDAC11-IN-2 | HDAC11-IN-2 (compound B6) is a high selective Histone Deacetylase 11 (HDAC11) inhibitor. HDAC11-IN-2 inhibits HDAC11 and HDAC8 with IC50s of 51.1 ×10-3 μM and 5 μM, respectively. HDAC11-IN-2 inhibits denovolipogenesis (DNL) and promotes fatty acid oxidation, thus mitigating hepaticlipid accumulation and pathological symptoms in MASLD mice. HDAC11-IN-2 enhances the phosphorylation of AMPKα1 at Thr172 through the inhibition of HDAC11, consequently modulating DNL and fatty acid oxidation in the liver[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2919766-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172157. | |
| HDAC11-IN-3 | HDAC11-IN-3 (Compound A9) is a selective HDAC11 inhibitor (IC50: 4.1 nM). HDAC11-IN-3 has inhibitory effects on U937 and OCI-AML2 acute myeloid leukemia (AML) cell lines (IC50: 10 μM). HDAC11-IN-3 has significant anti-AML activity, inducing apoptosis, cell cycle arrest, and differentiation. HDAC11-IN-3 upregulates the iron transporters transferrin (TF) and transferrin receptor (TFRC), and activates the p62-Keap1-Nrf2-HMOX1 pathway, which together lead to increased intracellular iron levels and induce ferroptosis in AML cells. HDAC11-IN-3 can be used alone or in combination with Cytarabine (HY-13605) for AML research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2989934-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173444. | |
| HDAC1/2-IN-3 | HDAC1/2-IN-3 is an inhibitor of HDAC1 and HDAC2 with IC50s of 0-5 and 5-10 nM, respectively. Synonyms: N-(2-amino-5-(thiophen-2-yl)phenyl)-7-((2-(dimethylamino)ethyl)amino)-3-isoquinolinecarboxamide. CAS No. 2121516-17-2. Molecular formula: C24H25N5OS. Mole weight: 431.55. | |
| HDAC1 Antibody [P23M13] | HDAC1,Histone Deacetylase 1 (HDAC1). Group: Antibodies. Alternative Names: HDAC1,Histone Deacetylase 1. Pack Sizes: 20ul. Product ID: F0735. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| HDAC2-IN-2 | HDAC2-IN-2 (compound 124) is an inhibitor of HDAC2 with Kd value of 0.1-1 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 332169-78-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164050. | |
| HDAC3 Inhibitor | HDAC3 inhibitor is an allosteric inhibitor of histone deacetylase 3 (HDAC3; Ki = 0.16 nM, IC50s = 0.95 nM). HDAC3 inhibitors increase histone acetylation and restore normal transcriptional patterns. Treatment with inhibitors primarily targeting HDAC3, including some with additional activity on HDAC1, led to improvement in motor function and working memory in N-terminal transgenic HD mice. Synonyms: Histone Deacetylase 3 Inhibitor; (E)-3-Phenyl-N-[[4-(propylaminocarbamoyl)phenyl]methyl]prop-2-enamide. Grade: ≥98%. CAS No. 2044701-99-5. Molecular formula: C20H23N3O2. Mole weight: 337.4. | |
| HDAC6 degrader-3 | HDAC6 degrader-3 is a potent and selective HDAC6 degrader via ternary complex formation and the ubiquitin-proteasome pathway with a DC50 value of 19.4 nM. HDAC6 degrader-3 has IC50s of 4.54 nM and 0.647 μM for HDAC6 and HDAC1, respectively. HDAC6 degrader-3 causes strong hyperacetylation of α-tubulin[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2785404-83-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152134. | |
| HDAC6-IN-3 | HDAC6-IN-3 is an antiprostate cancer drug that is an effective MAO-A (IC50 = 0.79 μM) and LSD1 inhibitor, and a potent and orally active HDAC6 inhibitor with IC50s ranging from 0.02 to 1.54 μM for HDAC1/2/3/6/8/10. Synonyms: N1-hydroxy-N8-(3-((methyl(prop-2-yn-1-yl)amino)methyl)phenyl)octanediamide. Molecular formula: C19H27N3O3. Mole weight: 345.44. | |
| HDAC6-IN-33 | HDAC6-IN-33 (compound 6) is a selective and irreversible HDAC6 inhibitor with an IC50 of 193 nM. HDAC6-IN-33 shows no activity against HDAC1-4. HDAC6-IN-33 is a tight-binding HDAC6 inhibitor capable of inhibiting HDAC6 via a two-step slow-binding mechanism[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2444302-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161304. | |
| HDAC8-IN-1 | HDAC8-IN-1 is a HDAC8 inhibitor with IC50 of 27.2 nM in cancer cell lines. Synonyms: (E)-N-hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide; VC-7933. Grade: 98% by HPLC. CAS No. 1417997-93-3. Molecular formula: C22H19NO3. Mole weight: 345.4. | |
| HDAC/BET-IN-1 | HDAC/BET-IN-1 shows submicromolar inhibitory activity against HDAC1 and 6 (IC50s = 0.163 μM and 0.067 μM), and BRD4 (Ki = 0.076 μM). It has potent antileukemia activity. Synonyms: N-(2-((8-(hydroxyamino)-8-oxooctyl)oxy)-5-(morpholinosulfonyl)phenyl)-3-methyl-4-oxo-2,4,5,6,7,8-hexahydrocyclohepta[c]pyrrole-1-carboxamide. Molecular formula: C29H40N4O8S. Mole weight: 604.71. | |
| HDAC-IN-1 | HDAC-IN-1, an analogue of MC 1568, is a Iia HDACs inhibitor that could probably influence myogenesis and adipogenesis. Uses: Hdac-in-1 is a iia hdacs inhibitor that could probably influence myogenesis and adipogenesis. Synonyms: MC1568; MC 1568; MC-1568; HDAC-IN-1; HDAC IN 1. Grade: 98%. CAS No. 1239610-44-6. Molecular formula: C17H15FN2O3. Mole weight: 314.31. | |
| HDAC-IN-2 | HDAC-IN-2, a selective HDAC inhibitor, has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.It is under Phase II trials against Multiple myeloma. IC50: 4 nM and 76 nM for. Uses: Hdac-in-2 is a selective hdac inhibitor that has been found to probably restrain the transcription and division of tumor oncogene and could also lead to the apoptosis of tumor cells.it is under phase ii trials against multiple myeloma. Synonyms: ACY-241; ACY 241; ACY241; HDAC-IN-2; Citarinostat; 2-((2-Chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide; UNII-441P620G3P; 441P620G3P; Citarinostat. Grade: 98%. CAS No. 1316215-12-9. Molecular formula: C24H26ClN5O3. Mole weight: 467.95. | |
| HDAC-IN-26 | HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 of 4.7 nM. Synonyms: (S)-N-(1-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-7-(isoxazol-3-yl)-7-oxoheptyl)-1-methylazetidine-3-carboxamide; N-[(1S)-1-[5-(2-fluorophenyl)-1H-imidazol-2-yl]-7-isoxazol-3-yl-7-oxo-heptyl]-1-methyl-azetidine-3-carboxamide. CAS No. 2410542-97-9. Molecular formula: C24H28FN5O3. Mole weight: 453.51. | |
| HDAC-IN-28 | HDAC-IN-28 is an inhibitor of HDAC that has potent activity against tumor growth and metastasis. Synonyms: N-(4-Methoxyphenyl)-N-[[5-(5-pyrimidinyl)-2-thienyl]methyl]-7-(hydroxyamino)-7-oxoheptanamide. CAS No. 1621154-88-8. Molecular formula: C23H26N4O4S. Mole weight: 454.54. | |
| HDAC-IN-32 | HDAC-IN-32 is a potent inhibitor of HDAC with IC50s of 5.2, 11 and 28 nM for HDAC1, HDAC2 and HDAC6, respectively. HDAC-IN-32 has potent antiproliferation activities against tumor cells. It exhibits strong antitumor efficacy in vivo, and induces anti-tumor immunity. Synonyms: 7-(3-(1H-benzo[d]imidazol-2-yl)phenoxy)-N-hydroxyheptanamide. Molecular formula: C20H23N3O3. Mole weight: 353.41. | |
| HDAC-IN-33 | HDAC-IN-33 is a potent inhibitor of HDAC with IC50s of 24, 46 and 47 nM for HDAC1, HDAC2 and HDAC6, respectively. HDAC-IN-33 has potent antiproliferation activities against tumor cells. It exhibits strong antitumor efficacy in vivo, and induces anti-tumor immunity. Synonyms: 8-(3-(1H-benzo[d]imidazol-2-yl)phenoxy)-N-hydroxyoctanamide. Molecular formula: C21H25N3O3. Mole weight: 367.44. | |
| HDAC-IN-4 | HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC50s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1252003-13-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128763. | |
| HDAC-IN-5 | HDAC-IN-5 is an inhibitor of histone deacetylase (HDAC). Synonyms: N-((1-Methyl-4-(4-phenylthiazol-2-yl)piperidin-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide; Benzamide, N-[[1-methyl-4-(4-phenyl-2-thiazolyl)-4-piperidinyl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]-; NU7. Grade: ≥95%. CAS No. 1314890-51-1. Molecular formula: C26H24F3N5O2S. Mole weight: 527.56. | |
| HDAC-IN-87 | HDAC-IN-87 (Compound XII6) is a nonselective HDAC inhibitor, with pIC50 of 6.9 (HDAC4) and 5.8 (HDAC6) respectively. HDAC-IN-87 has fungicidal activity against P. sorghi and P. pachyrhizi. HDAC-IN-87 shows an acute oral LD50 of greater than 500 mg/kg in male and female rats[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3039482-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173053. | |
| HDAC Inhibitor XVII ((E)-N-Hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamide, Histone Deacetylase Inhibitor XVII) | A cell-permeable N-hydroxycinnamide derivative that acts a highly potent and HDAC8-selective histone deacetylase inhibitor (IC50 = 27nM), displaying much reduced or little potency against HDAC1/3 (IC50 = 3.0uM), HDAC2/4/6/10/11 (IC50 >20uM), or total HDAC activity in HeLa nuclear extract (IC50 >10uM). Reported to preferentially inhibit the proliferation of human lung cancer cells CL1-5, H1299, and A549 (IC50 from 7 to 8uM), while being much less toxic to normal human lung IMR-90 cells (73% inhibition at 40uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??NO?, Primary Target IC50: 27nM. US Biological Life Sciences. | Worldwide |
| HDAC Inhibitor XXIII, Tubastatin A (N-Hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide, HCl) | A cell-permeable carbazolohydroxamate compound that acts as a highly potent, reversible and active-site zinc-binding HDAC6 inhibitor with excellent selectivity among other HDAC isozymes (IC50=0.015, 0.854, 16.4uM for HDAC6, HDAC8 and HDAC1, respectively) with no activity towards HDAC2, 3, 4, 7, 9, 10 and 11 (IC50>30uM). Shown to induce a-tubulin hyperacetylation at 2.5uM, and offer complete neuroprotection in primary cortical rat neuronal cells against homocysteic acid (HCA)-induced oxidative stress at 10uM with no noticeable neurotoxicity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| HDACs/mTOR Inhibitor 1 | HDACs/mTOR Inhibitor 1 is a dual HDACs and mTOR inhibitor, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM for HDAC1, HDAC6, mTOR, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induces tumor cell apoptosis with low toxicity in vivo. HDACs/mTOR Inhibitor 1 can be used in the research of hematologic malignancies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2271413-06-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114414. | |
| HDACs/mTOR Inhibitor 1 | HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. Grade: 98%. CAS No. 2271413-06-8. Molecular formula: C28H38N8O5. Mole weight: 566.65. | |
| H-D-Ala(1-Naph)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Ala(1-Naph)-Trt(2-Cl)-Resin; H-D-Ala(1-Naph)-Barlos Resin; β-(1-Naphthyl)-D-alanine 2-chlorotrityl resin. | |
| H-D-Ala(1-pyridyl)-OH 2HCl | H-D-Ala(1-pyridyl)-OH 2HCl. Molecular formula: C8H10N2O2·2HCl. Mole weight: 239.2. | |
| H-D-Ala-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Ala-Trt(2-Cl)-Resin; H-D-Ala-Barlos Resin; D-Alanine 2-chlorotrityl resin. | |
| H-D-Ala-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: D-alanine-2-chlorotrityl resin. | |
| H-D-Ala(2-Naph)-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-D-Ala(2-Naph)-Trt(2-Cl)-Resin; H-D-Ala(2-Naph)-Barlos Resin; β-(2-Naphthyl)-D-alanine 2-chlorotrityl resin. | |
| H-D-Ala(3-pyridyl)-OH | A reagent used in the synthesis of selective ligands derived from somatostatin antagonists. Synonyms: 3-(3-Pyridyl)-D-alanine; (R)-2-Amino-3-(pyridin-3-yl)propanoic acid. Grade: 95%. CAS No. 70702-47-5. Molecular formula: C8H10N2O2. Mole weight: 166.18. | |
| H-D-Ala(4-pyridyl)-OH 2HCl | H-D-Ala(4-pyridyl)-OH 2HCl. Synonyms: 3-(4-Pyridyl)-D-alanine dihydrochloride; (2R)-2-amino-3-pyridin-4-ylpropanoic acid dihydrochloride. Grade: 95%. CAS No. 174096-41-4. Molecular formula: C8H10N2O2·2HCl. Mole weight: 239.1. | |
| H-D-Ala-Ala-OH | H-D-Ala-Ala-OH. Synonyms: d-alanyl-l-alanine; N-D-Alanyl-L-alanine; (S)-2-((R)-2-Aminopropanamido)propanoic acid. Grade: 95%. CAS No. 1115-78-2. Molecular formula: C6H12N2O3. Mole weight: 160.17. | |
| H-D-ALA-D-ALA-D-ALA-D-ALA-D-ALA-OH | H-D-ALA-D-ALA-D-ALA-D-ALA-D-ALA-OH. Synonyms: Ala-Ala-Ala-Ala-Ala. CAS No. 10491-09-5. Molecular formula: C15H27N5O6. Mole weight: 373.40. | |
| H-D-Ala-D-Ala-D-Ala-D-Ala-OH | It is a substrate for D-aminopeptidase from Ochrobactrum anthropi. Synonyms: N-[2-((2-[(2-Aminopropanoyl)amino]propanoyl)amino)propanoyl]alanine; L-Alanine, N-[N-(N-L-alanyl-L-alanyl)-L-alanyl]-; (2-Isopropyl-1H-benzimidazol-1-yl)aceticacid. Grade: 95%. CAS No. 926-78-3. Molecular formula: C12H22N4O5. Mole weight: 302.33. | |
| H-D-Ala-D-Ala-D-Ala-OH | H-D-Ala-D-Ala-D-Ala-OH. Synonyms: D-Alanyl-D-alanyl-D-alanine; (R)-2-((R)-2-((R)-2-aminopropanamido)propanamido)propanoic acid. CAS No. 1114-94-9. Molecular formula: C9H17N3O4. Mole weight: 231.25. | |
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