A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Loganoside. CAS No. 18524-94-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0512.
Loganin
Loganin. Group: Biochemicals. Alternative Names: Meliatin; Loganoside. Grades: Plant Grade. CAS No. 18524-94-2. Pack Sizes: 20mg. Molecular Formula: C17H26O10, Molecular Weight: 390.382. US Biological Life Sciences.
Worldwide
Loganin
Loganin is isolated from the fruits of Cornus officinalis Sieb. et Zucc. It reduced malondialdehyde and increased superoxide dismutase in serum and kidney. It has great promise for the treatment of diabetic complications. Uses: Anti-inflammatory and anti-oxidant. Synonyms: 7-Hydroxy-6-desoxyverbenalin; Loganoside. Grade: 98%. CAS No. 18524-94-2. Molecular formula: C17H26O10. Mole weight: 390.39.
Logwood Extract
Logwood Extract. Applications: Used as coloring in the production of beverage, food, supplement and cosmetic industry. Group: Others. Synonyms: Logwood Extract; Haematoxylum campechianum L. Purity: 5-10:1 By TLC. Appearance: Black fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Wood. Species: Haematoxylum campechianum L. Logwood Extract; Haematoxylum campechianum L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-119.
Lokivetmab
Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody. Lokivetmab inhibits IL-31-mediated activation of pruritogenic signals in peripheral sensory neurons and reduces TH2-weighted inflammation. Lokivetmab demonstrates long-term efficacy in controlling pruritus and improving skin lesions in dogs with canine atopic dermatitis (CAD). Lokivetmab can be used for the research of atopic dermatitis (AD) in dogs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Canine IL31 Recombinant Antibody; CAN34D3-65; PF-06443537. CAS No. 1533403-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99301.
Loliolide
Loliolide is a germination inhibitor that is isolated from Sargassum ringgoldianum subsp. coreanum. Loliolide exhibits antioxidant activity to protect the cells against H2O2-induced cell damage or apoptosis. Synonyms: (3S,5R)-Loliolide. Grade: 98.0%. CAS No. 5989-2-6. Molecular formula: C11H16O3. Mole weight: 196.246.
Loliolide
Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinsons disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Loliolid; Digiprolactone. CAS No. 5989-2-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-118020A.
L-olivosyl-oleandolide 3-O-methyltransferase
The enzyme is involved in the biosynthesis of the macrolide antibiotic oleandomycin in Streptomyces antibioticus. It can also act on other monoglycosylated macrolactones, including L-rhamnosyl-erythronolide B and L-mycarosyl-erythronolide B. Group: Enzymes. Synonyms: OleY. Enzyme Commission Number: EC 2.1.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1842; L-olivosyl-oleandolide 3-O-methyltransferase; EC 2.1.1.239; OleY. Cat No: EXWM-1842.
LOM612
LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2173232-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101035.
Lomatium Dissectum Root (Whole) & (Cut & Sifted)
Lomatium Dissectum Root (Whole) & (Cut & Sifted).
CA, FL & NJ
Lombartinib impurity
Lombartinib impurity. Uses: For analytical and research use. Molecular formula: C25H24ClN5O5. Mole weight: 509.95. Catalog: APB10689.
Lombartinib impurity2
Lombartinib impurity2. Uses: For analytical and research use. CAS No. 1069122-99-1. Molecular formula: C7H7ClN2O2. Mole weight: 186.6. Catalog: APB1069122991.
Lombartinib impurity 3
Lombartinib impurity 3. Uses: For analytical and research use. Molecular formula: C12H10ClNO3. Mole weight: 251.67. Catalog: APB10690.
Lombartinib impurity 4
Lombartinib impurity 4. Uses: For analytical and research use. Molecular formula: C12H10ClNO3. Mole weight: 251.67. Catalog: APB10692.
Lombartinib impurity 5
Lombartinib impurity 5. Uses: For analytical and research use. Molecular formula: C18H15ClN2O4. Mole weight: 358.78. Catalog: APB10691.
Lombartinib impurity 6
Lombartinib impurity 6. Uses: For analytical and research use. Molecular formula: C18H15ClN2O4. Mole weight: 358.78. Catalog: APB10693.
lombricine kinase
Also acts on methylated lombricines such as thalassemine; the specificity varies with the source species. Group: Enzymes. Enzyme Commission Number: EC 2.7.3.5. CAS No. 9026-53-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3185; lombricine kinase; EC 2.7.3.5; 9026-53-3. Cat No: EXWM-3185.
Lomefloxacin-[d5]
Lomefloxacin-[d5] is the labelled salt of Lomefloxacin, which is a fluorinated quinolone antibacterial agent and a DNA gyrase antagonist. Synonyms: Lomefloxacin-D5 ; 1-Ethyl-d5-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid; Alkaflox-d5; Bareon-d5; Chimono-d5; Lomebact-d5; Lomflox-d5; Lomitas-d5; Lomoxin-d5; Maxaquin-d5; Mazaquin-d5; Orchacin-d5; Uniquin-d5. Molecular formula: C17H14D5F2N3O3. Mole weight: 356.38.
Lomefloxacin-[d5] hydrochloride
Lomefloxacin-[d5] hydrochloride is the labelled salt of Lomefloxacin, which is a fluorinated quinolone antibacterial agent and a DNA gyrase antagonist. Synonyms: Lomefloxacin-D5 hydrochloride; 1-Ethyl-d5-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox-d5; Bareon-d5; Chimono-d5; Lomebact-d5; Lomflox-d5; Lomitas-d5; Lomoxin-d5; Maxaquin-d5; Mazaquin-d5; Orchacin-d5; Uniquin-d5. Grade: 95% by HPLC; 98% atom D. Molecular formula: C17H14D5F2N3O3.HCl. Mole weight: 392.84.
Lomefloxacin·HCl 99+% (HPLC)
Lomefloxacin·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Lomefloxacin hydrochloride
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C17H19F2N3O3 · HCl. CAS No. 98079-51-7. Prepack ID 39370200-1g. Molecular Weight 387.81. See USA prepack pricing.
Lomefloxacin hydrochloride
Lomefloxacin hydrochloride is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections. Synonyms: Lomefloxacin hydrochloride; Maxaquin; Ny-198; Bareon; SC 4711; SC-4711; SC4711. Grade: >98%. CAS No. 98079-52-8. Molecular formula: C17H20ClF2N3O3. Mole weight: 387.81.
Lomefloxacin hydrochloride
Lomefloxacin hydrochloride (Okacyn) inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. Category: Active pharmaceutical ingredients. Synonyms: Lomefloxacin HCl, Okacyn, Maxaquin. CAS No. 98079-52-8. Product ID: API98079528. Molecular formula: C17H20ClF2N3O3. Mole weight: 387.81.
Lomefloxacin, Hydrochloride
Fluorinated quinolone antibacterial. DNA gyrase antagonist. Lomefloxacin HCl is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic. Lomefloxacin is an orally bioavailable, broad-spectrum fluoroquinolone antibiotic.1 In vitro, it inhibits growth of N. gonorrhoeae, E. coli, K. pneumoniae, P. vulgaris, S. epidermidis, and M. morganii (MIC90s = 0.1, 0.39, 0.39, 0.39, 0.39, and 0.78ug/ml, respectively). It also inhibits growth of S. aureus and methicillin-resistant S. aureus (MRSA; MIC90 = 3.13ug/ml for both) and of H. influenzae and ampicillin-resistant H. influenzae (MIC90 = 0.1ug/ml for both). In vivo, lomefloxacin inhibits the growth of P. mirabilis, E. coli, K. pneumoniae, and S. aureus (ED50s = 1.39, 1.45, 1.78, and 6.66mg/kg, respectively) in mouse models of systemic infection. It inhibits bacterial DNA gyrase, thereby inhibiting DNA synthesis and bacterial growth.2 Formulations containing lomefloxacin have been used in the treatment of bronchitis and urinary tr Group: Biochemicals. Alternative Names: 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Hydrochloride; Alkaflox; Bareon; Chimono; Lomebact; Lomef 400; Lomflox; Lomitas; Lomoxin; Maxaquin; Mazaquin; NY 198; Orchacin; SC 47111; Uniquin. Grades: Highly Purified. CAS No. 98079-52-8. Pack Sizes: 1g, 5g, 10g, 25g. Molecular Formula: C17H20ClF2N3O3, Molecular Weight: 387.81. US Biological Life Sciences.
Worldwide
Lomeguatrib
Lomeguatrib is an inhibitor of O6-methylguanine-DNA methyltransferase (MGMT). Lomeguatrib attenuates MGMT activity in vitro and in vivo. Lomeguatrib enhances the antitumor activity of temozolomide in both human melanoma and MCF-7 xenografts. Group: Biochemicals. Alternative Names: 6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine; 6-[(4-Bromo-2-thienyl)methoxy]-1H-purin-2-amine; 2-Amino-6-(4-bromothiophen-2-ylmethoxy)-9H-purine; PaTrin 2. Grades: Highly Purified. CAS No. 192441-08-0. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Lomeguatrib
Lomeguatrib is a O6-methylguanine-DNA methyltransferase (MGMT) inhibitor, with IC50s of 9 nM in cell-free assay and ~6?nM in MCF-7 cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PaTrin-2. CAS No. 192441-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13668.
Lomerizine
Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines. Category: Active pharmaceutical ingredients. CAS No. 101477-55-8. Product ID: API101477558. Molecular formula: C27H30F2N2O3. Mole weight: 468.54.
Lomerizine dihydrochloride
Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KB-2796. CAS No. 101477-54-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg. Product ID: HY-B0768A.
Lomerizine dihydrochloride
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine. Category: Active pharmaceutical ingredients. Synonyms: Terranas, Lomerizine 2HCl, Lomerizine hydrochloride, KB-2796. CAS No. 101477-54-7. Product ID: API101477547. Molecular formula: C27H30F2N2O3·2HCl. Mole weight: 541.46.
Lomerizine dihydrochloride
This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation. Synonyms: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride; Flometizinehydrochloride; Lomerizinedihydrochloride, 99%, anewL-andT-typecalciumchannelblocker; Lomerizine2HCl; KB-2796dihydrochlorideChemicalbook; Piperazine, 1-[bis (4-fluorophenyl) methyl]-4-[ (2, 3, 4-trimethoxyphenyl) methyl]-, hydrochloride (1: 2) ; Lomerizinedihydrochloride, >=99%; 1- (Bis (4-fluorophenyl) methyl) -4- (2, 3, 4-trimethoxybenzyl) piperazinedihydrochloride. CAS No. 101477-54-7. Product ID: PAP-0072. Molecular formula: C27H32Cl2F2N2O3. Category: Cardiovascular. Product Keywords: Cardiovascular Series; Lomerizine dihydrochloride; PAP-0072; Cardiovascular; C27H32Cl2F2N2O3; 101477-54-7. Appearance: white to tan. Standard: CP. Chemical Name: 1- (4, 4'-Difluorobenzhydryl) -4- (2, 3, 4-trimethoxybenzyl) piperazine·dihydrochloride. Grade: Pharmaceutical Grade. Solubility: DMSO: ≥30mg/mL. Storage: Inert atmosphere,2-8°C. Product Description: This product is a diphenylpiperazine calcium channel blocker with selective cerebral vasodilation.
A diphenylpiperazine calcium channel blocker. A selective cerebral vasodilator. Group: Biochemicals. Alternative Names: KB-2796; Terranas; 1-[bis (4-fluorophenyl) methyl]-4-[ (2, 3, 4-trimethoxyphenyl) methyl]piperazine. Grades: Highly Purified. CAS No. 101477-54-7. Pack Sizes: 10mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Lometrexol
Lometrexol (DDATHF), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DDATHF. CAS No. 106400-81-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14521.
Lometrexol disodium
Lometrexol (DDATHF) disodium, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol disodium can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol disodium has anticancer activity. Lometrexol disodium also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DDATHF disodium. CAS No. 120408-07-3. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg. Product ID: HY-14521A.
Lomitapide
Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEGR-733; BMS-201038. CAS No. 182431-12-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14667.
Lomitapide
Lomitapide. Group: Biochemicals. Alternative Names: N-(2,2,2-Trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9H-fluorene-9-carboxamide; AEGR 733; BMS 201038; BMS 201038-01; BMS 201238. Grades: Highly Purified. CAS No. 182431-12-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C39H37F6N3O2, Molecular Weight: 693.72. US Biological Life Sciences.
Worldwide
Lomitapide
Lomitapide (AEGR-733) is a small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for absorbing dietary lipids and transferring triglycerides onto apolipoprotein B (apo-B) in the assembly of very-low-density lipoprotein. Category: Active pharmaceutical ingredients. CAS No. 182431-12-5. Product ID: API182431125. Molecular formula: C39H37F6N3O2. Mole weight: 693.72.
Lomitapide Impurity 1
Lomitapide Impurity 1. Uses: For analytical and research use. CAS No. 182439-11-8. Molecular formula: C20H18F3NO3. Mole weight: 377.36. Catalog: APB182439118.
Lomitapide mesylate
Lomitapide (AEGR-733; BMS-201038) mesylate is an orally active microsomal triglyceride transfer protein (MTP) inhibitor and a selective mTORC1 inhibitor with lipid-lowering activity and BBB permeability. Lomitapide mesylate significantly reduces plasma LDL levels by blocking the assembly and secretion of very-low-density lipoprotein (VLDL). Lomitapide mesylate inhibits mTORC1 in an ATP-dependent manner, thereby inducing AMPK-independent autophagic cell death and suppressing cancer cell growth and apoptosis. Lomitapide mesylate also enhances tumor infiltration of CD8+ T cells. In addition, Lomitapide mesylate inhibits HDAC, improves endothelial function, effectively alleviates vascular inflammation and oxidative stress, and exerts neuroprotective effects in a cerebral ischemia/reperfusion injury model. Lomitapide mesylate can be used in research on related diseases such as colorectal cancer, breast cancer, melanoma, ischemic stroke, and familial hypercholesterolemia[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEGR-733 mesylate; BMS-201038 mesylate. CAS No. 202914-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14668.
Lomitapide Mesylate
Lomitapide Mesylate (BMS-201038 mesylate) is a methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein. Category: Active pharmaceutical ingredients. CAS No. 202914-84-9. Product ID: API202914849. Molecular formula: C40H41F6N3O5S. Mole weight: 789.83.
L-Omithine HCL
L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms. Synonyms: L-ORNITHINE HYDROCHLORIDE SALT;L-(+)-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE MONOHYDROCHLORIDE;L-ORNITHINE-OH HCL;L-ORNITHINE-OH HYDROCHLORIDE;L-ORN HCL;L-ORNITHINE HCL;L(+)-ORNITHINE HYDROCHLORIDE. CAS No. 3184-13-2. Product ID: PAP-0030. Molecular formula: C5H13ClN2O2. Category: Amino acid. Product Keywords: Amino Acid Series; L-Omithine HCL; PAP-0030; Amino acid; C5H13ClN2O2; 3184-13-2. Appearance: at 100.00 %. mild green bark. Chemical Name: L(+)-Ornithine hydrochloride. Grade: Pharmaceutical Grade. Solubility: H2O: 100 mg/mL. Storage: Keep in dark place,Inert atmosphere,Room temperature. Applications: L-ornithine hydrochloride has the effect of treating liver cirrhosis, enhancing human immunity and resisting fatigue. Melting Point: 245 °C (dec.)(lit.). Density: 1.57. Product Description: L-ornithine hydrochloride is an important basic raw material in pharmaceutical industry, an important metabolite in cells, and plays an important regulatory role in the elimination of liquid ammonia in living organisms.
Lomofungin
It is produced by the strain of Str. lomondensis var. lomondensis NRRL 3252. It is an antibiotic of the phenazine derivatives. It has anti-bacterial and fungal effects, but the anti-bacterial effects are weak. Synonyms: Lomondomycin; NSC 106995; NSC 156939; U-24792; 1-carbomethoxy-5-formyl-4,6,8-trihydroxyphenazine; 6-Formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid methyl ester. Grade: >95%. CAS No. 26786-84-5. Molecular formula: C15H10N2O6. Mole weight: 314.25.
Lomustine
Chloroethylnitrosourea derivative with antitumor activity. Similar to carmustine, chlorozotocin, nimustine, ranimustine. Antineoplastic. Group: Biochemicals. Alternative Names: N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea. Grades: Highly Purified. CAS No. 13010-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Lomustine
250mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H16ClN3O2. CAS No. 13010-47-4. Prepack ID 89981121-250mg. Molecular Weight 233.7. See USA prepack pricing.
Lomustine
Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CCNU; NSC 79037. CAS No. 13010-47-4. Pack Sizes: 10 mM * 1 mL in DMSO; 200 mg; 500 mg. Product ID: HY-13669.
Lomustine EP impurity C
Lomustine EP impurity C. Uses: For analytical and research use. CAS No. 2387-23-7. Molecular formula: C13H24N2O. Mole weight: 224.34. Catalog: APB2387237.
Lomustine Related Compound B
Lomustine Related Compound B. Uses: For analytical and research use. CAS No. 13908-11-7. Mole weight: 204.70. Catalog: AP13908117.
Lomustine Related Compound C
Lomustine Related Compound C. Uses: For analytical and research use. CAS No. 2387-23-7. Mole weight: 224.34. Catalog: AP2387237.
Lomustine Related Compound D
Lomustine Related Compound D. Uses: For analytical and research use. CAS No. 54749-91-6. Mole weight: 233.70. Catalog: AP54749916.
Lonafarnib
Lonafarnib. Group: Biochemicals. Alternative Names: 4-[2-[4-[(11R)-3, 10-Dibromo-8-chloro-6, 11-dihydro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336. Grades: Highly Purified. CAS No. 193275-84-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H31Br2ClN4O2. US Biological Life Sciences.
Worldwide
Lonafarnib
Lonafarnib (Sch66336) is a potent and orally active, and CNS-penetrant farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch66336. CAS No. 193275-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15136.
Lonafarnib-[d9]
Lonafarnib-[d9] is an isotope laballed analog of Lonafarnib. Lonafarnib is a farnesyltransferase inhibitor (FTI) used for the treatment of progeria. Synonyms: Lonafarnib D9. Grade: 95% by HPLC; 95% atom D. CAS No. 1197367-02-4. Molecular formula: C27H22D9Br2ClN4O2. Mole weight: 647.88.
Loncastuximab
Loncastuximab (RB4v1.2) is an anti-CD19 monoclonal antibody. Loncastuximab has antitumor activity and can be used in the research of Non-Hodgkin Lymphoma (NHL) and Diffuse Large B-cell Lymphoma (DLBCL). Loncastuximab is capable of synthesizing the ADC molecule Loncastuximab tesirine (HY-P99349)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RB4v1.2. CAS No. 1875032-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99711.
Loncastuximab tesirine
Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). The antibody portion is Loncastuximab (HY-P99711), and the drug-linker conjugate for ADC is Tesirine (HY-128952). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Loncastuximab tesirine-lpyl; ADCT-402. CAS No. 1879918-31-6. Pack Sizes: 100 μg; 200 μg; 500 μg; 1 mg. Product ID: HY-P99349.
Londamocitinib
Londamocitinib (AZD4604) is a potent and selective JAK1 inhibitor with IC50 at 0.54 nM. Londamocitinib has anti-inflammatory activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD4604; JAK1-IN-7. CAS No. 2241039-81-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126294.
long-chain-3-hydroxyacyl-CoA dehydrogenase
This enzyme was purified from the mitochondrial inner membrane. The enzyme has a preference for long-chain substrates, and activity with a C16 substrate was 6- to 15-fold higher than with a C4 substrate (cf. EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase). Group: Enzymes. Synonyms: β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Enzyme Commission Number: EC 1.1.1.211. CAS No. 84177-52-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0116; long-chain-3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.211; 84177-52-6; β-hydroxyacyl-CoA dehydrogenase; long-chain 3-hydroxyacyl coenzyme A dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase; LCHAD. Cat No: EXWM-0116.
long-chain acyl-[acyl-carrier-protein] reductase
Catalyses the reaction in the opposite direction. This enzyme, purified from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the NAD(P)H-dependent reduction of an activated fatty acid (acyl-[acp]) to the corresponding aldehyde. Together with EC 4.1.99.5, octadecanal decarbonylase, it is involved in alkane biosynthesis. The natural substrates of the enzyme are C16 and C18 activated fatty acids. Requires Mg2+. Group: Enzymes. Synonyms: long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Enzyme Commission Number: EC 1.2.1.80. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1183; long-chain acyl-[acyl-carrier-protein] reductase; EC 1.2.1.80; long-chain acyl-[acp] reductase; fatty acyl-[acyl-carrier-protein] reductase; acyl-[acp] reductase. Cat No: EXWM-1183.
long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme from pig liver can accept substrates with acyl chain lengths of 6 to at least 16 carbon atoms. The highest activity was found with C12, and the rates with C8 and C16 were 80 and 70%, respectively. The enzyme from rat can accept substrates with C8-C22. It is most active with C14 and C16, and has no activity with C4, C6 or C24. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.8, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Enzyme Commission Number: EC 1.3.8.8. CAS No. 59536-74-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1415; long-chain acyl-CoA dehydrogenase; EC 1.3.8.8; 59536-74-2; palmitoyl-CoA dehydrogenase; palmitoyl-coenzyme A dehydrogenase; long-chain acyl-coenzyme A dehydrogenase; long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase; ACADL (gene name). Cat No: EXWM-1415.
long-chain acyl-CoA ω-monooxygenase
The enzymes from solanaceous plants are involved in the biosynthesis of stigmatic estolide, a lipid-based polyester that forms a major component of the exudate. Group: Enzymes. Synonyms: long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Enzyme Commission Number: EC 1.14.13.204. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0806; long-chain acyl-CoA ω-monooxygenase; EC 1.14.13.204; long-chain acyl-CoA ω-hydroxylase; CYP86A22 (gene name); CYP52M1 (gene name). Cat No: EXWM-0806.
long-chain acyl-protein thioester reductase
Together with a hydrolase component (EC 3.1.2.2 and EC 3.1.2.14) and a synthetase component (EC 6.2.1.19), this enzyme forms a multienzyme fatty acid reductase complex that produces the long-chain aldehyde substrate of the bacterial luciferase enzyme (EC 1.14.14.3). The enzyme is acylated by receiving an acyl group from EC 6.2.1.19, and catalyses the reduction of the acyl group, releasing the aldehyde product. The enzyme is also able to accept the acyl group from a long-chain acyl-CoA. Group: Enzymes. Synonyms: luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Enzyme Commission Number: EC 1.2.1.50. CAS No. 50936-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1154; long-chain acyl-protein thioester reductase; EC 1.2.1.50; 50936-56-6; luxC (gene name); acyl-CoA reductase; acyl coenzyme A reductase; long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming); long-chain-fatty-acyl-CoA reductase. Cat No: EXWM-1154.
long-chain-alcohol dehydrogenase
Hexadecanol is a good substrate. Group: Enzymes. Synonyms: long-chain alcohol dehydrogenase; fatty alcohol oxidoreductase. Enzyme Commission Number: EC 1.1.1.192. CAS No. 76774-36-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0095; long-chain-alcohol dehydrogenase; EC 1.1.1.192; 76774-36-2; long-chain alcohol dehydrogenase; fatty alcohol oxidoreductase. Cat No: EXWM-0095.
long-chain-alcohol O-fatty-acyltransferase
Transfers saturated or unsaturated acyl residues of chain-length C18 to C20 to long-chain alcohols, forming waxes. The best acceptor is cis-icos-11-en-1-ol. Group: Enzymes. Synonyms: wax synthase; wax-ester synthase. Enzyme Commission Number: EC 2.3.1.75. CAS No. 64060-40-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2255; long-chain-alcohol O-fatty-acyltransferase; EC 2.3.1.75; 64060-40-8; wax synthase; wax-ester synthase. Cat No: EXWM-2255.
long-chain-alcohol oxidase
Oxidizes long-chain fatty alcohols; best substrate is dodecyl alcohol. Group: Enzymes. Synonyms: long-chain fatty alcohol oxidase; fatty alcohol oxidase; fatty alcohol:oxygen oxidoreductase; long-chain fatty acid oxidase. Enzyme Commission Number: EC 1.1.3.20. CAS No. 129430-50-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0402; long-chain-alcohol oxidase; EC 1.1.3.20; 129430-50-8; long-chain fatty alcohol oxidase; fatty alcohol oxidase; fatty alcohol:oxygen oxidoreductase; long-chain fatty acid oxidase. Cat No: EXWM-0402.
long-chain-aldehyde dehydrogenase
The best substrate is dodecylaldehyde. Group: Enzymes. Synonyms: long-chain aliphatic aldehyde dehydrogenase; long-chain fatty aldehyde dehydrogenase; fatty aldehyde:NAD+ oxidoreductase. Enzyme Commission Number: EC 1.2.1.48. CAS No. 59298-89-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1151; long-chain-aldehyde dehydrogenase; EC 1.2.1.48; 59298-89-4; long-chain aliphatic aldehyde dehydrogenase; long-chain fatty aldehyde dehydrogenase; fatty aldehyde:NAD+ oxidoreductase. Cat No: EXWM-1151.
long-chain alkane monooxygenase
The enzyme, characterized from the bacterium Geobacillus thermodenitrificans NG80-2, is capable of converting alkanes ranging from C15 to C36 into their corresponding primary alcohols. The FMNH2 cofactor is provided by an FMN reductase. Group: Enzymes. Enzyme Commission Number: EC 1.14.14.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0925; long-chain alkane monooxygenase; EC 1.14.14.28. Cat No: EXWM-0925.
long-chain-enoyl-CoA hydratase
Acts in the reverse direction. The best substrate is oct-3-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA. Group: Enzymes. Synonyms: long-chain enoyl coenzyme A hydratase. Enzyme Commission Number: EC 4.2.1.74. CAS No. 62009-81-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5058; long-chain-enoyl-CoA hydratase; EC 4.2.1.74; 62009-81-8; long-chain enoyl coenzyme A hydratase. Cat No: EXWM-5058.
The enzyme ligates long chain fatty acids (with aliphatic chain of 13-22 carbons) to an acyl-carrier protein. Not identical with EC 6.2.1.3 long-chain-fatty-acid-CoA ligase. Group: Enzymes. Synonyms: acyl-[acyl-carrier-protein] synthetase (ambiguous); acyl-ACP synthetase (ambiguous); stearoyl-ACP synthetase; acyl-acyl carrier protein synthetase (ambiguous); long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming). Enzyme Commission Number: EC 6.2.1.20. CAS No. 77322-37-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5679; long-chain-fatty-acid-[acyl-carrier-protein] ligase; EC 6.2.1.20; 77322-37-3; acyl-[acyl-carrier-protein] synthetase (ambiguous); acyl-ACP synthetase (ambiguous); stearoyl-ACP synthetase; acyl-acyl carrier protein synthetase (ambiguous); long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming). Cat No: EXWM-5679.
long-chain-fatty-acid-CoA ligase
Acts on a wide range of long-chain saturated and unsaturated fatty acids, but the enzymes from different tissues show some variation in specificity. The liver enzyme acts on acids from C6 to C20; that from brain shows high activity up to C24. Group: Enzymes. Synonyms: acyl-CoA synthetase; fatty acid thiokinase (long chain); acyl-activating enzyme; palmitoyl-CoA synthase; lignoceroyl-Co. Enzyme Commission Number: EC 6.2.1.3. CAS No. 9013-18-7. ACS3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5687; long-chain-fatty-acid-CoA ligase; EC 6.2.1.3; 9013-18-7; acyl-CoA synthetase; fatty acid thiokinase (long chain); acyl-activating enzyme; palmitoyl-CoA synthase; lignoceroyl-CoA synthase; arachidonyl-CoA synthetase; acyl coenzyme A synthetase; acyl-CoA ligase; palmitoyl coenzyme A synthetase; thiokinase; palmitoyl-CoA ligase; acyl-coenzyme A ligase; fatty acid CoA ligase; long-chain fatty acyl coenzyme A synthetase; oleoyl-CoA synthetase; stearoyl-CoA synthetase; long chain fatty acyl-CoA synthetase; long-chain acyl CoA synthetase; fatty acid elongase; LCFA synthetase; pristanoyl-CoA synthetase; ACS3; long-chain acyl-CoA synthetase I; long-chain acyl-CoA synthetase II; fatty acyl-coenzyme A synthetase; long-chain acyl-coenzyme A synthetase; FAA1. Cat No: EXWM-5687.
long-chain fatty acid ω-monooxygenase
The plant enzyme CYP704B1, which is involved in the synthesis of sporopollenin, a complex polymer found at the outer layer of spores and pollen, acts on palmitate (18:0), stearate (18:0) and oleate (18:1). The plant enzyme CYP86A1 also acts on laurate (12:0). The enzyme from the yeast Starmerella bombicola (CYP52M1) acts on C16 to C20 saturated and unsaturated fatty acids and can also hydroxylate the (ω-1) position. The mammalian enzyme CYP4A acts on laurate (12:0), myristate (14:0), palmitate (16:0), oleate (18:1), and arachidonate (20:4). Group: Enzymes. Synonyms: CYP704B1 (gene name); CYP52M1 (gene name); CYP4A (gene name); CYP86A (gene name). Enzyme Commission Number: EC 1.14.13.205. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0807; long-chain fatty acid ω-monooxygenase; EC 1.14.13.205; CYP704B1 (gene name); CYP52M1 (gene name); CYP4A (gene name); CYP86A (gene name). Cat No: EXWM-0807.