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Selpercatinib (LOXO-292, ARRY-192) is a potent and specific RET (c-RET) inhibitor with IC50 values of 1 nM, 2 nM, 2 nM, 4 nM, 2 nM, 2 nM for WT RET, RET V804M, RET V804L, RET A883F, RET M918T and RET S891A respectively. Group: Inhibitors. Alternative Names: ARRY-192. CAS No. 2152628-33-4. Pack Sizes: 5mg. Product ID: S8781. Formula: C29H31N7O3. Smiles: CC(C)(COC1=CN2C(=C(C=N2)C#N)C(=C1)C3=CN=C(C=C3)N4CC5CC(C4)N5CC6=CN=C(C=C6)OC)O. Storage Conditions: 3 years -20°C powder.
United States; Europe
Loxodellic acid
Loxodellic acid, as the principal constant constituent, is a lower homologue of glomelliferic acid from the new species Parmelia loxodella Essl. from Australia (including Tasmania) and New Zealand. Synonyms: Benzoic acid, 2-hydroxy-4-[[2-hydroxy-4-methoxy-6-(2-oxopentyl)benzoyl]oxy]-6-propyl-. CAS No. 67121-37-3. Molecular formula: C23H26O8. Mole weight: 430.45.
Loxodellonic acid
Loxodellonic acid is a depside from the Lichen Neofuscelia subincerta. Synonyms: ACMC-20mit2; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylicacid, 8-hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-propyl-. CAS No. 113689-49-9. Molecular formula: C23H24O8. Mole weight: 428.43.
Loxodin
Loxodin is a depsidone isolated from Parmelia flavescentireagens Gyel. Synonyms: Neoloxodic acid; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 3,8-dihydroxy-11-oxo-6-pentyl-1-valeryl-, methyl ester (8CI). CAS No. 29813-50-1. Molecular formula: C25H28O8. Mole weight: 456.48.
Loxoprofen is a non-steroidal anti-inflammatory drug in the propionic acid derivatives group, which also includes ibuprofen and naproxen among others. It is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic Acid; 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic Acid; 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid. Grade: >98%. CAS No. 68767-14-6. Molecular formula: C15H18O3. Mole weight: 246.3.
Loxoprofen impurity 13
Loxoprofen impurity 13. Uses: For analytical and research use. Molecular formula: C18H22O5. Mole weight: 318.3. Catalog: APB08474.
Loxoprofen Impurity 14
Loxoprofen Impurity 14. Uses: For analytical and research use. CAS No. 81762-82-5. Molecular formula: C17H22O3. Mole weight: 274.36. Catalog: APB81762825.
Loxoprofen Impurity 20
Loxoprofen Impurity 20. Uses: For analytical and research use. Alternative Names: methyl 2-(4-(hydroxymethyl)phenyl)propanoate. CAS No. 1823911-62-1. Molecular formula: C11H14O3. Mole weight: 194.23. Catalog: APB1823911621.
Loxoprofen Impurity 21
Loxoprofen Impurity 21. Uses: For analytical and research use. CAS No. 492-37-5. Molecular formula: C9H10O2. Mole weight: 150.18. Catalog: APB492375.
Loxoprofen Impurity 22
Loxoprofen Impurity 22. Uses: For analytical and research use. CAS No. 88378-22-7. Molecular formula: C15H20O4. Mole weight: 264.32. Catalog: APB88378227.
Loxoprofen impurity 24
Loxoprofen impurity 24. Uses: For analytical and research use. CAS No. 371753-20-7. Molecular formula: C15H20O3. Mole weight: 248.32. Catalog: APB371753207.
Loxoprofen Impurity 24
Loxoprofen Impurity 24. Uses: For analytical and research use. Alternative Names: methyl 1-(4-(1-methoxy-1-oxopropan-2-yl)benzyl)-2-oxocyclopentanecarboxylate. CAS No. 308279-38-1. Molecular formula: C18H22O5. Mole weight: 318.36. Catalog: APB308279381.
Loxoprofen Impurity 26
Loxoprofen Impurity 26. Uses: For analytical and research use. Alternative Names: 2-(4-(chloromethyl)phenyl)propanoic acid. CAS No. 80530-55-8. Molecular formula: C10H11ClO2. Mole weight: 198.65. Catalog: APB80530558.
Loxoprofen Impurity 28
Loxoprofen Impurity 28. Uses: For analytical and research use. CAS No. 141-28-6. Molecular formula: C10H18O4. Mole weight: 202.25. Catalog: APB141286.
Loxoprofen Impurity 31
Loxoprofen Impurity 31. Uses: For analytical and research use. CAS No. 371753-19-4. Molecular formula: C15H20O3. Mole weight: 248.32. Catalog: APB371753194.
Loxoprofen Impurity 32
Loxoprofen Impurity 32. Uses: For analytical and research use. CAS No. 111128-12-2. Molecular formula: C10H11BrO2. Mole weight: 243.1. Catalog: APB111128122.
Loxoprofen Impurity 33
Loxoprofen Impurity 33. Uses: For analytical and research use. CAS No. 2172861-70-8. Molecular formula: C10H11BrO2. Mole weight: 243.1. Catalog: APB2172861708.
Loxoprofen Impurity 34
Loxoprofen Impurity 34. Uses: For analytical and research use. Alternative Names: methyl 3-(4-(1-methoxy-1-oxopropan-2-yl)benzyl)-2-oxocyclopentanecarboxylate. Molecular formula: C18H22O5. Mole weight: 318.36. Catalog: APB01609.
Loxoprofen Impurity 35
Loxoprofen Impurity 35. Uses: For analytical and research use. Alternative Names: 2-(4-((1-hydroxy-2-oxocyclopentyl)methyl)phenyl)propanoic acid. CAS No. 1091621-62-3. Molecular formula: C15H18O4. Mole weight: 262.3. Catalog: APB1091621623.
Loxoprofen Impurity 35
Loxoprofen Impurity 35. Uses: For analytical and research use. CAS No. 1072443-75-4. Molecular formula: C11H13BrO2. Mole weight: 257.13. Catalog: APB1072443754.
Loxoprofen Impurity 36
Loxoprofen Impurity 36. Uses: For analytical and research use. Molecular formula: C30H34O5. Mole weight: 474.6. Catalog: APB08475.
Loxoprofen Impurity 37
Loxoprofen Impurity 37. Uses: For analytical and research use. Alternative Names: (E)-2,2'-(((2'-oxo-[1,1'-bi(cyclopentylidene)]-2,3'-diyl)bis(methylene))bis(4,1-phenylene))dipropanoic acid. Molecular formula: C30H34O5. Mole weight: 474.59. Catalog: APB02160.
Loxoprofen Impurity 38
Loxoprofen Impurity 38. Uses: For analytical and research use. Alternative Names: 6-(4-(1-carboxyethyl)phenyl)-6-oxohexanoic acid. CAS No. 2514697-36-8. Molecular formula: C15H18O5. Mole weight: 278.30. Catalog: APB2514697368.
Loxoprofen impurity 40
Loxoprofen impurity 40. Uses: For analytical and research use. CAS No. 1152440-23-7. Molecular formula: C19H24O5. Mole weight: 332.4. Catalog: APB1152440237.
Loxoprofen Impurity 41
Loxoprofen Impurity 41. Uses: For analytical and research use. CAS No. 36601-73-7. Molecular formula: C7H8O3. Mole weight: 140.14. Catalog: APB36601737.
Loxoprofen Impurity 42
Loxoprofen Impurity 42. Uses: For analytical and research use. Alternative Names: 2-(4-(methoxymethyl)phenyl)propanoic acid. CAS No. 1551612-94-2. Molecular formula: C11H14O3. Mole weight: 194.23. Catalog: APB1551612942.
Loxoprofen Impurity 42
Loxoprofen Impurity 42. Uses: For analytical and research use. Molecular formula: C18H20O2. Mole weight: 268.36. Catalog: APB08476.
Loxoprofen Impurity 43
Loxoprofen Impurity 43. Uses: For analytical and research use. Molecular formula: C18H20O2. Mole weight: 268.36. Catalog: APB08477.
Loxoprofen Impurity 44
Loxoprofen Impurity 44. Uses: For analytical and research use. Molecular formula: C17H18O2. Mole weight: 254.33. Catalog: APB08478.
Loxoprofen Impurity 44
Loxoprofen Impurity 44. Uses: For analytical and research use. Alternative Names: 2-(4-(hydroxymethyl)phenyl)propanoic acid. CAS No. 88416-60-8. Molecular formula: C10H12O3. Mole weight: 180.20. Catalog: APB88416608.
Loxoprofen Impurity 45
Loxoprofen Impurity 45. Uses: For analytical and research use. Molecular formula: C17H18O2. Mole weight: 254.33. Catalog: APB08479.
Loxoprofen Impurity 48
Loxoprofen Impurity 48. Uses: For analytical and research use. Alternative Names: 4-(1-methoxy-1-oxopropan-2-yl)benzyl 2-oxocyclopentanecarboxylate. Molecular formula: C17H20O5. Mole weight: 304.34. Catalog: APB02060.
Loxoprofen Impurity 49
Loxoprofen Impurity 49. Uses: For analytical and research use. Alternative Names: 2-(4-(((2-oxocyclopentanecarbonyl)oxy)methyl)phenyl)propanoic acid. Molecular formula: C16H18O5. Mole weight: 290.31. Catalog: APB02059.
Loxoprofen Impurity 50
Loxoprofen Impurity 50. Uses: For analytical and research use. CAS No. 145679-19-2. Molecular formula: C10H10O4. Mole weight: 194.19. Catalog: APB145679192.
Loxoprofen Impurity 50
Loxoprofen Impurity 50. Uses: For analytical and research use. Alternative Names: 6-methoxy-5-(4-(1-methoxy-1-oxopropan-2-yl)benzyl)-6-oxohexanoic acid. Molecular formula: C18H24O6. Mole weight: 336.38. Catalog: APB01608.
Loxoprofen Impurity 51
Loxoprofen Impurity 51. Uses: For analytical and research use. Alternative Names: methyl 2-((4-(1-methoxy-1-oxopropan-2-yl)benzyl)oxy)cyclopent-1-enecarboxylate. Molecular formula: C18H22O5. Mole weight: 318.36. Catalog: APB02056.
Loxoprofen Impurity 52
Loxoprofen Impurity 52. Uses: For analytical and research use. CAS No. 69956-76-9. Molecular formula: C15H16O3. Mole weight: 244.29. Catalog: APB69956769.
Loxoprofen Impurity 53
Loxoprofen Impurity 53. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08480.
Loxoprofen Impurity 54
Loxoprofen Impurity 54. Uses: For analytical and research use. Alternative Names: methyl 2-(4-(4-methylbenzyl)phenyl)propanoate. Molecular formula: C18H20O2. Mole weight: 268.35. Catalog: APB02058.
Loxoprofen Impurity 56
Loxoprofen Impurity 56. Uses: For analytical and research use. Alternative Names: 2-(4-(4-methylbenzyl)phenyl)propanoic acid. Molecular formula: C17H18O2. Mole weight: 254.32. Catalog: APB02057.
Loxoprofen Impurity 57
Loxoprofen Impurity 57. Uses: For analytical and research use. Alternative Names: 2-(4-(2-methylbenzyl)phenyl)propanoic acid. Molecular formula: C17H18O2. Mole weight: 254.32. Catalog: APB02054.
Loxoprofen Impurity 58
Loxoprofen Impurity 58. Uses: For analytical and research use. CAS No. 10472-24-9. Molecular formula: C7H10O3. Mole weight: 142.15. Catalog: APB10472249.
Loxoprofen Impurity 59
Loxoprofen Impurity 59. Uses: For analytical and research use. Alternative Names: 6-(4-(1-ethoxy-1-oxopropan-2-yl)phenyl)-5-oxohexanoic acid. Molecular formula: C17H22O5. Mole weight: 306.35. Catalog: APB01607.
Loxoprofen Impurity 60
Loxoprofen Impurity 60. Uses: For analytical and research use. CAS No. 334948-52-6. Molecular formula: C13H18O8. Mole weight: 302.28. Catalog: APB334948526.
Loxoprofen Impurity 61
Loxoprofen Impurity 61. Uses: For analytical and research use. Molecular formula: C18H22O5. Mole weight: 318.37. Catalog: APB08481.
Loxoprofen Impurity 62
Loxoprofen Impurity 62. Uses: For analytical and research use. Molecular formula: C19H22O7. Mole weight: 362.38. Catalog: APB08483.
Loxoprofen Impurity 63
Loxoprofen Impurity 63. Uses: For analytical and research use. Molecular formula: C15H17NaO4. Mole weight: 284.29. Catalog: APB08482.
Loxoprofen Impurity 64
Loxoprofen Impurity 64. Uses: For analytical and research use. CAS No. 639857-67-3. Molecular formula: C14H18O. Mole weight: 202.3. Catalog: APB639857673.
Loxoprofen Impurity 66
Loxoprofen Impurity 66. Uses: For analytical and research use. Molecular formula: C15H20O5. Mole weight: 280.32. Catalog: APB08485.
Loxoprofen Impurity 67
Loxoprofen Impurity 67. Uses: For analytical and research use. Molecular formula: C16H20O3. Mole weight: 260.33. Catalog: APB08484.
Loxoprofen Impurity 68
Loxoprofen Impurity 68. Uses: For analytical and research use. Molecular formula: C15H20O3. Mole weight: 248.32. Catalog: APB08487.
Loxoprofen Impurity 69
Loxoprofen Impurity 69. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08486.
Loxoprofen Impurity 70
Loxoprofen Impurity 70. Uses: For analytical and research use. CAS No. 825-25-2. Molecular formula: C10H14O. Mole weight: 150.22. Catalog: APB825252.
Loxoprofen Impurity 71
Loxoprofen Impurity 71. Uses: For analytical and research use. Molecular formula: C15H20O5. Mole weight: 208.32. Catalog: APB08490.
Loxoprofen Impurity 72
Loxoprofen Impurity 72. Uses: For analytical and research use. Molecular formula: C17H22O5. Mole weight: 306.36. Catalog: APB08489.
Loxoprofen Impurity 73
Loxoprofen Impurity 73. Uses: For analytical and research use. Molecular formula: C17H22O5. Mole weight: 306.36. Catalog: APB08488.
Loxoprofen Impurity 74
Loxoprofen Impurity 74. Uses: For analytical and research use. Molecular formula: C18H24O6. Mole weight: 336.38. Catalog: APB08491.
Loxoprofen Impurity 75
Loxoprofen Impurity 75. Uses: For analytical and research use. Molecular formula: C18H24O6. Mole weight: 336.38. Catalog: APB08492.
Loxoprofen Impurity 76
Loxoprofen Impurity 76. Uses: For analytical and research use. CAS No. 77846-90-3. Molecular formula: C10H12O4. Mole weight: 196.2. Catalog: APB77846903.
Loxoprofen Impurity 77
Loxoprofen Impurity 77. Uses: For analytical and research use. Molecular formula: C15H21NaO5. Mole weight: 304.32. Catalog: APB08495.
Loxoprofen Impurity 78
Loxoprofen Impurity 78. Uses: For analytical and research use. Molecular formula: C18H22O5. Mole weight: 318.37. Catalog: APB08493.
Loxoprofen Impurity 79
Loxoprofen Impurity 79. Uses: For analytical and research use. CAS No. 2274853-20-0. Molecular formula: C18H22O5. Mole weight: 318.37. Catalog: APB2274853200.
Loxoprofen Impurity 79
Loxoprofen Impurity 79. Uses: For analytical and research use. Molecular formula: C15H18O4. Mole weight: 262.31. Catalog: APB08494.
Loxoprofen impurity 80
Loxoprofen impurity 80. Uses: For analytical and research use. CAS No. 1027957-36-3. Molecular formula: C17H20O5. Mole weight: 304.34. Catalog: APB1027957363.
Loxoprofen Impurity 80
Loxoprofen Impurity 80. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08496.
Loxoprofen impurity 81
Loxoprofen impurity 81. Uses: For analytical and research use. CAS No. 83648-77-5. Molecular formula: C15H20O3. Mole weight: 248.32. Catalog: APB83648775.
Loxoprofen Impurity 81
Loxoprofen Impurity 81. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08497.
Loxoprofen Impurity 82
Loxoprofen Impurity 82. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08498.
Loxoprofen Impurity 83
Loxoprofen Impurity 83. Uses: For analytical and research use. Molecular formula: C18H24O5. Mole weight: 320.39. Catalog: APB08499.