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| Product | Description | |
|---|---|---|
| N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt | plasmin substrate. Group: Fluorescence/luminescence spectroscopy. |  |
| N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt | N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Synonyms: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. Grades: ≥98% by TLC. CAS No. 88793-79-7. Molecular formula: C28H38N6O9S. Mole weight: 634.7. |  |
| N-p-Tosyl-L-phenylalanine | N-p-Tosyl-L-phenylalanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NCIOpen2_009805, Oprea1_534866, MLS000776584, ZERO/006235, ALBB-006226, CID309599, NSC211907, SMR000371829, EU-0000301, 2-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoic acid, 13505-32-3. Product Category: Heterocyclic Organic Compound. CAS No. 13505-32-3. Molecular formula: C16H17NO4S. Mole weight: 319.37. Purity: 0.96. IUPACName: 2-[(4-methylphenyl)sulfonylamino]-3-phenylpropanoic acid. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC=CC=C2)C(=O)O. Density: 1.303g/cm³. Product ID: ACM13505323. Alfa Chemistry ISO 9001:2015 Certified. |  |
| NPY 5RA972 | NPY 5RA972. Group: Biochemicals. Grades: Purified. CAS No. 439861-56-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| NPY 5RA972 | NPY5RA972 is a neuropeptide Y Y5 antagonist. Synonyms: NPY5RA972; NPY-5-RA-972; NPY 5 RA 972; N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide. Grades: ≥98% by HPLC. CAS No. 439861-56-0. Molecular formula: C21H25N3O2. Mole weight: 351.44. | |
| N-Pyrazinylcarbonyl-L-phenylalanine | N-Pyrazinylcarbonyl-L-phenylalanine. Group: Biochemicals. Alternative Names: N-(2-pyrazinylcarbonyl)-L-phenylalanine. Grades: Highly Purified. CAS No. 114457-94-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C14H13N3O3. US Biological Life Sciences. | Worldwide |
| N-Pyrazinylcarbonyl-L-phenylalanine methyl ester | Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates. Group: Biochemicals. Alternative Names: N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester; 3-Phenyl-2-[ (pyrazine-2-carbonyl) amino]propionic Acid Methyl Ester. Grades: Highly Purified. CAS No. 73058-37-4. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C??H??N?O?, Molecular Weight: 285.3. US Biological Life Sciences. | Worldwide |
| N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester | N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bortezomib Impurity R. Appearance: White Powder. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.29. Purity: 0.95. Product ID: ACM73058374. Alfa Chemistry ISO 9001:2015 Certified. Categories: DTXSID90503277. | |
| N-Pyrazinyl carbonyl phenyl alanine (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid) | N-Pyrazinyl carbonyl phenyl alanine (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid). Group: Biochemicals. Alternative Names: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-Pyrazinyl carbonyl phenyl alanine-d8 | N-Pyrazinyl carbonyl phenyl alanine-d8. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| N-Pyrazinyl carbonyl phenyl alanine Methyl Ester (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester) | N-Pyrazinyl carbonyl phenyl alanine Methyl Ester (3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester). Group: Biochemicals. Alternative Names: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| N-Pyridin-2-yl-Oxalamic Acid Ethyl Ester | Synonyms: EdoxaBan impurity K. Grades: > 95%. CAS No. 41374-72-5. Molecular formula: C9H10N2O3. Mole weight: 194.19. | |
| N-(Pyridin-3-ylmethyl)ethanamine | N-(Pyridin-3-ylmethyl)ethanamine (CAS# 3000-75-7) is used as a reagent in organic synthesis, in particular, that of bis-nicotine derivatives which act as inhibitors of cholinesterases and β-amyloid aggregation. It is also used in the synthesis of [11C]EMPA which acts as a potential PET tracer for orexin 2 receptors. N-(Pyridin-3-ylmethyl)ethanamine is also a nicotinic analog. Synonyms: N-(Pyridin-3-ylmethyl)ethylamine; N-Ethyl-3-pyridinemethanamine; N-Ethyl-N-(3-pyridylmethyl)amine; N-Ethyl-N-(pyridin-3-ylmethyl)amine; N-Ethyl[(3-pyridyl)methyl]amine; N-Ethyl[(pyridin-3-yl)methyl]amine; 3-[(Ethylamino)methyl]pyridine; α-Ethylamino-3-Picoline. Grades: ≥95%. CAS No. 3000-75-7. Molecular formula: C8H12N2. Mole weight: 136.19. | |
| N-Pyridin-4-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide | N-Pyridin-4-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-PYRIDIN-4-YL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-BENZAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 864759-38-6. Molecular formula: C18H21BN2O3. Mole weight: 324.18194. Product ID: ACM864759386. Alfa Chemistry ISO 9001:2015 Certified. | |
| N- (Pyridin-4-Ylmethyl) Methanesulfonamide | N- (Pyridin-4-Ylmethyl) Methanesulfonamide. Group: Biochemicals. Grades: Reagent Grade. CAS No. 349404-63-3. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| N-Pyrrolo-2'-deoxycytidine | N-Pyrrolo-2'-deoxycytidine. Group: Biochemicals. Alternative Names: 6-Methyl-3- (b-D-2-deoxyribofuranosyl) pyrrolo[2, 3-d]pyrimidin-2-one. Grades: Highly Purified. CAS No. 382137-74-8. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C12H15N3O4. US Biological Life Sciences. | Worldwide |
| NQ301 | NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC 50 of 10 mg/mL. Uses: Scientific research. Group: Signaling pathways. CAS No. 130089-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101054. |  |
| NQ301 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NQ 301 | NQ 301 is a CD45 inhibitor with IC50 value of 200 nM. It can block inflammation in a delayed-type hypersensitivity model in vivo. Synonyms: NQ-301; NQ 301; NQ301. 2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione. Grades: ≥98% by HPLC. CAS No. 130089-98-4. Molecular formula: C18H12ClNO3. Mole weight: 325.75. | |
| NQDI 1 | NQDI 1. Group: Biochemicals. Grades: Purified. CAS No. 175026-96-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NQDI-1 | NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. Synonyms: NQDI1; NQDI-1; NQDI 1. CAS#175026-96-7. Grades: 98%. CAS No. 175026-96-7. Molecular formula: C19H13NO4. Mole weight: 319.31. | |
| NQDI-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NQO1 substrate | NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304503-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114315. | |
| NQTrp | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NQTrp | NQTrp, also called 1,4-Naphthoquinon-2-yl-L-tryptophan, inhibits amyloid β (Aβ) oligomerization and fibrillization (IC50 = 50 nM for formation of fibrils from Aβ1-42) to treat Alzheimer's disease. Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: NQTrp; NQ-Trp; NQ Trp; (2S)-2-[(1,4-dioxonaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid; 185351-19-3; nqtrp; TRY001; DTXSID30717912; ZINC100222454; KB-274843; N-(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)-L-tryptophan; L-Tryptophan, N-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-; NQTrp|N-(1,4-Dihydro-1,4-dioxo-2-naphthalenyl)-L-tryptophan. CAS No. 185351-19-3. Molecular formula: C21H16N2O4. Mole weight: 360.36. | |
| N-(Quinolin-4-yl)acetamide | N-(Quinolin-4-yl)acetamide. Group: Biochemicals. Grades: Highly Purified. CAS No. 32433-28-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N-Quinolin-8-ylacetamide | N-Quinolin-8-ylacetamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-Acetamidoquinoline, 8-Acetylaminoquinoline, N-8-Quinolinylacetamide, Quinoline, 8-acetamido-, 8-(Acetylamino)quinoline, Acetamide, N-8-quinolinyl-, N-Quinolin-8-yl-acetamide, ACETAMIDE, N-8-QUINOLYL-, CCRIS 1686, N-(quinolin-8-yl)acetamide, Oprea1_284229, Oprea1_790091, NSC17020, MolPort-001-892-197, STK370914, AIDS020638, NSC 130773, AIDS-020638, CID36591, BRN 0135601. Product Category: Heterocyclic Organic Compound. CAS No. 33757-42-5. Molecular formula: C11H10N2O. Mole weight: 186.21 g/mol. Purity: 0.96. IUPACName: N-quinolin-8-ylacetamide. Canonical SMILES: CC(=O)NC1=CC=CC2=C1N=CC=C2. Density: 1.242g/cm³. Product ID: ACM33757425. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide | N-(Quinoxalin-2-yl)-4-(quinoxalin-2-ylamino)benzenesulfonamide, an intriguing chemical substance, has garnered interest in the biomedical domain as a plausible remedy for assorted cancer types. This compound exerts its therapeutic effects by curbing certain enzymes and provoking apoptosis in malignant cells, thereby causing their demise. Although promising, further scientific investigations and clinical deliberations are fundamental to ascertain its potency and risk profiles. Grades: 98.0%. Molecular formula: C22H16N6O2S. Mole weight: 428.474. | |
| N-[(R)-1-Phenylethyl]acetamide | N-[(R)-1-Phenylethyl]acetamide. Group: Biochemicals. Alternative Names: (+)-N-(1-Phenylethyl)acetamide; (R)-1-Acetamido-1-phenylethane; (R)-N-Acetyl-1-phenylethylamine; (α R) -N- (α -Methylphenyl) acetamide. Grades: Highly Purified. CAS No. 36283-44-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide | N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Product Category: Heterocyclic Organic Compound. CAS No. 1217846-28-0. Molecular formula: C12H13N3O. Mole weight: 215.25. Purity: 0.96. IUPACName: N-[(1R)-1-phenylethyl]imidazole-1-carboxamide. Canonical SMILES: CC(C1=CC=CC=C1)NC(=O)N2C=CN=C2. Product ID: ACM1217846280. Alfa Chemistry ISO 9001:2015 Certified. | |
| N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide | N-[(R)-(+)-1-Phenylethyl]imidazole-1-carboxamide. Group: Biochemicals. Alternative Names: (R)-N-(1-Phenylethyl)-1H-imidazole-1-carboxamide. Grades: Highly Purified. CAS No. 1217846-28-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C12H13N3O. US Biological Life Sciences. | Worldwide |
| NR2F6 modulator-1 | NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. NR2F6 modulator-1 can be used for researching immune modulation and modulation of cancer stem cell activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 904449-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147228. | |
| NRC-11 | NRC-11 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP1), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Ser-Val-Phe-Arg-Lys-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Leu-Asp-His-Tyr-Leu-NH2. Grades: ≥96%. Molecular formula: C129H209N37O30. Mole weight: 2758.32. | |
| NRC-12 | NRC-12 is an antimicrobial peptide found in Hippoglossoides platessoides (American plaice AP2), and has antibacterial and antifungal activity. Synonyms: Gly-Trp-Lys-Lys-Trp-Phe-Asn-Arg-Ala-Lys-Lys-Val-Gly-Lys-Thr-Val-Gly-Gly-Leu-Ala-Val-Asp-His-Tyr-Leu-NH2. Grades: ≥97%. Molecular formula: C135H209N39O30. Mole weight: 2858.40. | |
| NRC-13 | NRC-13 is an antimicrobial peptide found in American plaice AP3, Hippoglossoides platessoides Fabricius. It has antimicrobial activity against gram-negative bacteria, gram-positive bacteria and Fungi. Synonyms: H-Gly-Trp-Arg-Thr-Leu-Leu-Lys-Lys-Ala-Glu-Val-Lys-Thr-Val-Gly-Lys-Leu-Ala-Leu-Lys-His-Tyr-Leu-NH2; glycyl-L-tryptophyl-L-arginyl-L-threonyl-L-leucyl-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-alpha-glutamyl-L-valyl-L-lysyl-L-threonyl-L-valyl-glycyl-L-lysyl-L-leucyl-L-alanyl-L-leucyl-L-lysyl-L-histidyl-L-tyrosyl-L-leucinamide; (4S, 7S, 10S, 13S, 16S, 19S, 22S, 25S, 31S, 34S, 37S, 40S, 43S)-10-((1H-imidazol-5-yl)methyl)-43-((2S, 5S, 8S, 11S, 14S, 17S, 20S, 23S)-23-((1H-indol-3-yl)methyl)-26-amino-5, 8-bis(4-aminobutyl)-20-(3-guanidinopropyl)-17-((R)-1-hydroxyethyl)-11, 14-diisobutyl-2-methyl-4, 7, 10, 13, 16, 19, 22, 25-octaoxo-3, 6, 9, 12, 15, 18, 21, 24-octaazahexacosanamido)-13, 25, 37-tris(4-aminobutyl)-4-carbamoyl-7-(4-hydroxybenzyl)-34-((R)-1-hydroxyethyl)-16, 22-diisobutyl-31, 40-diisopropyl-2, 19-dimethyl-6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36, 39, 42-tridecaoxo-5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35, 38, 41-tridecaazahexatetracontan-46-oic acid. Grades: ≥97%. Molecular formula: C125H211N35O28. Mole weight: 2652.28. | |
| NRC-17 | NRC-17 is an antimicrobial peptide found in Glyptocephalus cynoglossus L. (Witch flounder GC3.8), and has antibacterial and antifungal activity. Synonyms: H-Gly-Trp-Lys-Lys-Trp-Leu-Arg-Lys-Gly-Ala-Lys-His-Leu-Gly-Gln-Ala-Ala-Ile-Lys-Gly-Leu-Ala-Ser-OH. Grades: ≥98%. Molecular formula: C116H190N36O26. Mole weight: 2505.02. | |
| NRC-2694 | NRC-2694 is a small molecule antagonist of epidermal growth factor receptor (EGFR) signalling pathways, for the treatment of solid tumors. Synonyms: NRC-2694; NRC 2694; NRC2694; N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine; NRC-2694; NRC 2694; NRC2694; 4-Quinazolinamine, N-(3-ethynylphenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-. CAS No. 936446-61-6. Molecular formula: C24H26N4O3. Mole weight: 418.49. | |
| NR-CL | Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. Synonyms: Nicotinamideribosidechloride; NicotinamideB-DRibosideChloride(WX900111); NicotinamideRiboside.Cl; Nicotimideribosidechloride; Pyridinium, 3-(aminocarbonyl)-1-β -D-ribofuranosyl-, chloride(1:1); 3-carbamoyChemicalbookl-1-((2R, 3R, 4S, 5R)-3, 4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-iumchloride; 3-Carbamoyl-1-(β -D-ribofuranosyl)pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride. CAS No. 23111-00-4. Product ID: PAP-0088. Molecular formula: C11H15ClN2O5. Product Keywords: Other Active Pharmaceutical Ingredients; NR-CL; PAP-0088; ; C11H15ClN2O5; 23111-00-4. Appearance: White Powder. Chemical Name: Pyridinium,3-(aminocarbonyl)-1-β-D-ribofuranosyl-,chloride(1:1). Grade: Pharmaceutical Grade. Color: White. Solubility: Soluble to 100 mM in DMSO and to 100 mM in water. Storage: under inert gas (nitrogen or Argon) at 2-8°C. Product Description: Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents a source of vitamin B3. |  |
| Nrf2 activator-1 | Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 ( Nrf2 ). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230697-41-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145390. | |
| Nrf2 activator-12 | Nrf2 activator-12 (compund 10v) potently activates Nrf2 (EC50=83.5 nM) and exhibits promising pharmacological properties, reversing disease progression and alleviating demyelination in an experimental autoimmune encephalomyelitis mouse model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3020661-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169201. | |
| Nrf2-Activator-12G | Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinsons Disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1554271-18-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-115849. | |
| Nrf2 Activator II, AI-1 (Ethyl-4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate) | A cell-permeable chloro-quinolinone compound that selectively and covalently modifies Kelch-like ECH-associated protein 1 (Keap1)-Cys151 and represses Keap1 function and reduces Nrf2 (Nuclear factor E2-related factor 2)-Keap1 interaction. Shown to stabilize Nrf2 by inhibiting the Keap1-driven ubiquitination of Nrf2 and thereby activating the Nrf2-ARE (antioxidant response element) pathway (EC50 = 2.7uM in neuroblastoma IMR-32 cells). Offers protection against H2O2 induced oxidative stress, but unlike tert-butylhydroquinone AI-1 does not act as a free radical scavenger. Its anti-oxidant effects are mediated via Nrf2 induced antioxidant response. Does not affect mutant ARE where GC are substituted with AT within the core ARE sequence. Group: Biochemicals. Grades: Highly Purified. CAS No. 75483-04-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Nrf2 Activator III, TAT-14 Peptide, H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH | A 14-mer peptide (LQLDEETGEFLPIQ) conjugated to cell-penetrating trans-activating transcriptional activator (TAT) sequence (YGRKKRRQRRRLQ) that targets the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) binding site on Kelch-like ECH-associated protein 1 (Keap1). Competitively disrupts Nrf2-Keap1 interaction and stabilizes cytosolic Nrf2, and promotes its nuclear translocation and binding to the antioxidant response element (ARE). Exhibits anti-inflammatory properties and increases heme-oxygenase-1 gene expression (~75uM). Also shown to suppress LPS-induced TNF-a secretion in THP-1 monocytes (~ 37.5uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1362661-34-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Nrf2 degrader 1 | Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with anticancer effects. Nrf2 degrader 1 inhibits cancer cells growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3025286-00-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162307. | |
| Nrf2-IN-1 | Nrf2-IN-1 is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2). Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1610022-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101025. | |
| Nrf2-IN-3 | Nrf2-IN-3 (Compound R16) is a small-molecule NRF2 inhibitor and increases reactive oxygen species (ROS) production. Nrf2-IN-3 selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions, leading to proteasome-dependent NRF2 degradation in cells. Nrf2-IN-3 sensitizes KEAP1-mutated tumor cells to Cisplatin (HY-17394), Gefitinib (HY-50895), and KEAP1 G333C-mutated xenograft to Cisplatin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6325-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149508. | |
| N-(R)-Glycidyl Phthalimide | Reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants. Group: Biochemicals. Alternative Names: 2-[(2R)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione; (R)-2-(Oxiranylmethyl)-1H-isoindole-1,3(2H)-dione; (R)-N-(2,3-Epoxypropan-1-yl)phthalimide; N-((2R)-Oxiran-2-ylmethyl)phthalimide. Grades: Highly Purified. CAS No. 181140-34-1. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| NRP1 antagonist 1 | NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC 50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569598-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133034. | |
| Nrpe | Nrpe. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (all-E)-1,2-di-2-Palmitin. Product Category: Heterocyclic Organic Compound. CAS No. 30576-47-7. Molecular formula: C57H100NO8P. Mole weight: 958.38. Product ID: ACM30576477. Alfa Chemistry ISO 9001:2015 Certified. | |
| NRPE | NRPE. Group: Biochemicals. Alternative Names: (all-E)-1,2-di-2-palmitin. Grades: Highly Purified. CAS No. 30576-47-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C57H100NO8P. US Biological Life Sciences. | Worldwide |
| N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH | N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH is a specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) with a Ki of 0.027±0.003 μM. Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts it into a potent inhibitor of angiotensin-converting enzyme (ACE). Synonyms: Cpp-AAF-pAb; Cfp-aaf-pab; N-(1-Carboxy-3-phenylpropyl)-ala-ala-phe-p-aminobenzoate; N-(1-Carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate; L-Phenylalaninamide, N-(1-carboxy-3-phenylpropyl)-L-alanyl-L-alanyl-N-(4-carboxyphenyl)-; N-(1-Carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide. Grades: ≥95%. CAS No. 116560-97-5. Molecular formula: C32H36N4O7. Mole weight: 588.66. | |
| N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide | Synonyms: N-((RS)-2-Hydroxy-propyl)-VL-anilide; L-Leucinamide, N-(2-hydroxypropyl)-L-valyl-N-phenyl- (9CI). CAS No. 282726-24-3. Molecular formula: C20H33N3O3. Mole weight: 363.49. | |
| N-rt-Butyloxycarbonyl Gabapentin | Protected Gabapentin. Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-[[[ (1, 1-Dimethylethoxy) carbonyl]amino]methyl]-cyclohexaneacetic Acid; 2- [1- [ (tert-Butoxycarbonylamino) methyl] cyclohexyl] acetic Acid; [1- (tert-Butoxycarbonylamino methyl ) cyclohexyl] acetic Acid. Grades: Highly Purified. CAS No. 227626-60-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| NRTN (Neurturin), Human | It is a cell-penetrating peptide (CPP) derived from human neurturin protein. NRTN can permeate cell membrane at low micromolar concentration and has no obvious effect on cell membrane. NRTN has high activity as a siRNA transfection reagent. Synonyms: H-Gly-Ala-Ala-Glu-Ala-Ala-Ala-Arg-Val-Tyr-Asp-Leu-Gly-Leu-Arg-Arg-Leu-Arg-Gln-Arg-Arg-Arg-Leu-Arg-Arg-Glu-Arg-Val-Arg-Ala-OH. Grades: >98%. Molecular formula: C150H268N64O39. Mole weight: 3592.20. | |
| Nru I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 50% of the dna fragments can be ligated and 90% of them can be recut. in the presence of 10% peg ligation is better. Group: Restriction Enzymes. Purity: 500 U; 2500U. TCG↑CGA AGC↓GCT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Nocardia rubra. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1142RE. |  |
| NRWC | NRWC is an antimicrobial peptide found in Bacillus subtilis, and has antibacterial activity. Synonyms: Asn-Arg-Trp-Cys-Phe-Ala-Gly-Asp-Asp; NRWC (Bacteriocin). Grades: >98%. Molecular formula: C46H62N14O15S. Mole weight: 1083.14. | |
| NRX-204647 | NRX-204647 is a Retinoic acid receptor gamma-selective inverse agonist. Synonyms: NRX204647; NRX-204647; NRX 204647. 4-((1E,3Z)-3-(hydroxyimino)-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl)benzoic acid. Grades: 98%. CAS No. 1351452-80-6. Molecular formula: C24H27NO3. Mole weight: 377.78. | |
| NRX-252114 | NRX-252114 is a potent enhancer of the interaction between ?-catenin, and its cognate E3 ligase, SCF?-TrCP. NRX-252114 enhances the binding of pSer33/S37A ?-catenin peptide for ?-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant ?-catenin degradation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763260-39-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111836. | |
| NRX-252262 | NRX-252262 is a potent enhancer of the interaction between ?-Catenin, and its cognate E3 ligase, SCF?-TrCP, induces mutant ?-catenin degradation, with an EC50 of 3.8 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2438637-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111760. | |
| NRX-4204 | NRX-4204, also known as NRX-194204 and AGN-194204, is an orally bioavailable synthetic retinoid X receptor (RXR) agonist with potential antineoplastic and anti-inflammatory activities. Rexinoid NRX 194204 selectively binds to and activates RXRs. Because RXRs can form heterodimers with several nuclear receptors (NRs), RXR activation by this agent may result in a broad range of gene expression depending on the effector DNA response elements activated. Rexinoid NRX 194204 may inhibit the tumor-necrosis factor (TNF)-mediated release of nitric oxide (NO) and interleukin 6 (IL6) and may inhibit tumor cell proliferation. This agent appears to be less toxic than RAR-selective ligands. Synonyms: IRX4204; IRX-4204; IRX 4204; NRX4204; NRX-4204; NRX 4204; NRX194204; NRX 194204; NRX-194204; AGN194204; AGN 194204; AGN-194204; VTP 194204; VTP194204; VTP-194204. CAS No. 220619-73-8. Molecular formula: C24H32O2. Mole weight: 352.51. | |
| NS | NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase. | |
| NS-018 | NS-018, a selective JAK2 as well as Src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. It is still under Phase I/II trial against Myelofibrosis. IC50: 470 nM for Ba/F3-JAK2V617F cell. Uses: Ns-018 is a selective jak2 as well as src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. Synonyms: NS-018; NS 018; NS018; UNII-56R994WX4L; 56R994WX4L; GTPL7839; GTPL 7839; GTPL-7839; SCHEMBL14954406; UQTPDWDAYHAZNT-AWEZNQCLSA-N. Grades: 98%. CAS No. 1239358-86-1. Molecular formula: C21H20FN7. Mole weight: 389.43. | |
| NS-018 hydrochloride | The hydrochloride salt form of NS-018 which is a selective JAK2 as well as Src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. It is still under Phase I/II trial against Myelofibrosis. IC50: 470 nM for Ba/F3-JAK2. Uses: The hydrochloride salt form of ns-018 which is a selective jak2 as well as src family tyrosine kinases inhibitor that could probably induce the apoptosis of tumor cells. Synonyms: NS018 hydrochloride; NS 018 hydrochloride. Grades: 98%. CAS No. 1239358-85-0. Molecular formula: C21H21ClFN7. Mole weight: 425.89. | |
| NS 102 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| NS11021 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| NS 11021 | NS 11021. Group: Biochemicals. Grades: Purified. CAS No. 956014-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| NS 11021 | NS 11021 is a potent and specific Ca 2+ -activated big-conductance K + Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956014-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13103. | |
| NS 11021 | NS 11021 is an activator of large-conductance Ca2+-activated potassium channels. It has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro. Synonyms: NS-11021; NS 11021; NS11021. N'-[3,5-Bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl-phenyl]thiourea. Grades: ≥98% by HPLC. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24. | |
| NS-11021 | NS-11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle. NS11021 enhances erectile responses in rats. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NS-11021; NS 11021; NS11021. Product Category: Activators. Appearance: Solid powder. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24. Purity: >98%. IUPACName: N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea. Canonical SMILES: S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC2=CC=C(Br)C=C2C3=NNN=N3. Product ID: ACM956014190. Alfa Chemistry ISO 9001:2015 Certified. | |
| NS 11394 | NS 11394 is a drug with selectivity for the α3 and α5 subtypes. It acts as a subtype-selective positive allosteric modulator at GABAA receptors. It is used as an analgesic for use in chronic or neuropathic pain. It is unique in having superior efficacy at alpha(3) receptors and low efficacy at alpha(1) receptors in vitro. It has an excellent pharmacokinetic profile, which correlates with pharmacodynamic endpoints, yielding a high level of confidence in deriving in vivo conclusions anchored to an in vitro selectivity profile and allowing for translation to higher species. It impairs memory in both rats and mice because of its efficacy at GABA(A)-alpha(5) receptors. It is potent and highly effective in rodent anxiety models. It has a significantly reduced side effect profile in rat and mouse, even at full CNS receptor occupancy. Uses: Ns-11394 is used as an analgesic for use in chronic or neuropathic pain. Synonyms: NS-11394; NS 11394; NS11394; 2-[3-[5-(2-hydroxypropan-2-yl)benzimidazol-1-yl]phenyl]benzonitrile;NS-11394;3'-[5-(1-Hydroxy-1-methylethyl)-1H-benzimidazol-1-yl]-[1,1'-biphenyl]-2-carbonitrile. Grades: >98 %. CAS No. 951650-22-9. Molecular formula: C23H19N3O. Mole weight: 353.42. | |
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