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| Product | Description | |
|---|---|---|
| Sophoricoside | Sophoricoside. Group: Biochemicals. Alternative Names: Genistein 4?-glucoside. Grades: Plant Grade. CAS No. 152-95-4. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences. |  Worldwide |
| Sophoridine | Sophoridine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6882-68-4. Pack Sizes: 20mg. Molecular Formula: C15H24N2O, Molecular Weight: 248.36. US Biological Life Sciences. | Worldwide |
| Sophorolipid | Sophorolipid is a glycolipid biosurfactant, one of the well-known high-performance biosurfactants, which is mainly produced by non-pathogenic yeasts. Sophorolipid has an excellent environmental profile in terms of toxicity, biodegradability and surface activity better than synthetic analogs. Applications: Sophorolipid has great potential applications in the food and cosmetic industries as natural emulsifiers, wetting agents, biopreservatives due to its potent antimicrobial activity and good skin compatibility. sophorolipid has been explored for various applications in the pharmaceutical industry as a drug delivery vehicle and therapeutic agent. Category: Natural extract. Synonyms: (E)-17-[(2R,3R,4S,5S,6R)-6-(acetyloxymethyl)-3-[(2S,3R,4S,5S,6R)-6-(acetyloxymethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxyoctadec-9-enoic acid. Product ID: PIPE-0294. Molecular formula: C34H58O15. Mole weight: 706.8. InChIKey: ZTOKUMPYMPKCFX-CZNUEWPDSA-N. |  |
| Soquelitinib | Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CPI-818. CAS No. 2226636-04-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150298. |  |
| Sorafenib | Sorafenib Inhibitor. Uses: Scientific use. Product Category: T0093L. CAS No. 284461-73-0. |  |
| Sorafenib | Sorafenib is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Synonyms: BAY 43-9006. Grade: >98%. CAS No. 284461-73-0. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.82. |  |
| Sorafenib | Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death. Category: Active pharmaceutical ingredients. CAS No. 284461-73-0. Product ID: API284461730. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.82. | |
| Sorafenib | Sorafenib (Bay 43-9006) is a potent oral active multikinase inhibitor. Sorafenib blocks autophosphorylation and activity of receptor tyrosine kinases (VEGFR-2, VEGFR-3) and RAF family kinases, thereby suppressing the RAF/MEK/ERK and PI3K/Akt pathways, inhibiting STAT3 phosphorylation, and selectively inhibiting the MAPK pathway in cancer cells. Sorafenib induces cell cycle arrest, autophagy, apoptosis, and PARP cleavage, reduces Bcl-2, Bcl-XL, cyclin D1 levels, and activates Bak and Bax. Sorafenib inhibits tumor growth and metastasis in mouse and rat models. Sorafenib can be used for cancer research, such as colon, breast, non-small-cell lung cancer (NSCLC), ovarian, pancreatic, melanoma, colorectal and hepatocellular carcinoma[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006. CAS No. 284461-73-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10201. | |
| Sorafenib-13C,d3 | Sorafenib-13C,d3 is the 13C- and deuterium labeled Sorafenib. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bay 43-9006-13C,d3. CAS No. 1210608-86-8. Pack Sizes: 100 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-10201S2. | |
| Sorafenib (BAY 43-9006) | Sorafenib is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity. Group: Inhibitors. Alternative Names: NSC-724772,BAY 43-9006. CAS No. 284461-73-0. Pack Sizes: 20mg. Product ID: S7397. Formula: C21H16ClF3N4O3. Smiles: CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Sorafenib-d3 | Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Donafenib; Bay 43-9006-d3. CAS No. 1130115-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-10201S. | |
| Sorafenib-[d3] | Sorafenib-[d3] is the labelled analogue of Sorafenib, which is a potent RAF kinase inhibitor and an antineoplastic. Synonyms: Sorafenib-d3; Sorafenib-(methyl-d3); 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-(methyl-d3)-2-pyridinecarboxamide. Grade: ≥98%; ≥99% atom D. CAS No. 1130115-44-4. Molecular formula: C21H13D3ClF3N4O3. Mole weight: 467.84. | |
| Sorafenib-d4 | Sorafenib D4 is the deuterium labeled Sorafenib. Sorafenib is an inhibitor of multikinase (Raf-1, B-Raf, and VEGFR-3 IC50s of 6 nM, 20 nM, and 22 nM, respectively). Category: Active pharmaceutical ingredients. CAS No. 1207560-07-3. Product ID: API1207560073. Molecular formula: C21H16ClF3N4O3. Mole weight: 468.85. | |
| Sorafenib-[d4] | Sorafenib-[d4] is the labelled analogue of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: Sorafenib-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1207560-07-3. Molecular formula: C21H12D4ClF3N4O3. Mole weight: 468.85. | |
| Sorafenib Impurity 10 | Sorafenib Impurity 10. Uses: For analytical and research use. CAS No. 284461-82-1. Molecular formula: C22H18ClF3N4O3. Mole weight: 478.86. Catalog: APB284461821. |  |
| Sorafenib Impurity 11 | Sorafenib Impurity 11. Uses: For analytical and research use. CAS No. 1290546-48-3. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.83. Catalog: APB1290546483. | |
| Sorafenib Impurity 11073 | Sorafenib Impurity 11073. Uses: For analytical and research use. CAS No. 2090542-70-2. Molecular formula: C7H7FN2O3. Mole weight: 186.14. Catalog: APB2090542702. | |
| Sorafenib Impurity 13 | Sorafenib Impurity 13. Uses: For analytical and research use. CAS No. 583840-04-4. Molecular formula: C20H14ClF3N4O4. Mole weight: 466.8. Catalog: APB583840044. | |
| Sorafenib Impurity 14 | Sorafenib Impurity 14. Uses: For analytical and research use. CAS No. 2206827-14-5. Molecular formula: C17H19N3O4. Mole weight: 329.36. Catalog: APB2206827145. | |
| Sorafenib Impurity 15 | Sorafenib Impurity 15. Uses: For analytical and research use. CAS No. 871555-75-8. Molecular formula: C14H9ClF3NO2. Mole weight: 315.68. Catalog: APB871555758. | |
| Sorafenib Impurity 16 | Sorafenib Impurity 16. Uses: For analytical and research use. CAS No. 2206827-12-3. Molecular formula: C16H17N3O4. Mole weight: 315.33. Catalog: APB2206827123. | |
| Sorafenib Impurity 17 | Sorafenib Impurity 17. Uses: For analytical and research use. CAS No. 53750-66-6. Molecular formula: C6H3Cl2NO. Mole weight: 176. Catalog: APB53750666. | |
| Sorafenib Impurity 2 | Sorafenib Impurity 2. Uses: For analytical and research use. CAS No. 114780-06-2. Molecular formula: C8H9ClN2O. Mole weight: 184.62. Catalog: APB114780062. | |
| Sorafenib Impurity 22 | Sorafenib Impurity 22. Uses: For analytical and research use. CAS No. 777-37-7. Molecular formula: C7H3ClF3NO2. Mole weight: 225.55. Catalog: APB777377. | |
| Sorafenib Impurity 24 | Sorafenib Impurity 24. Uses: For analytical and research use. CAS No. 39974-35-1. Molecular formula: C7H3ClF3NO2. Mole weight: 225.55. Catalog: APB39974351. | |
| Sorafenib Impurity 27 | Sorafenib Impurity 27. Uses: For analytical and research use. CAS No. 583840-03-3. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.83. Catalog: APB583840033. | |
| Sorafenib Impurity 31 | Sorafenib Impurity 31. Uses: For analytical and research use. CAS No. 62476-58-8. Molecular formula: C7H5ClF3N. Mole weight: 195.57. Catalog: APB62476588. | |
| Sorafenib Impurity 34 | Sorafenib Impurity 34. Uses: For analytical and research use. CAS No. 121-50-6. Molecular formula: C7H5ClF3N. Mole weight: 195.57. Catalog: APB121506. | |
| Sorafenib Impurity 43 | Sorafenib Impurity 43. Uses: For analytical and research use. CAS No. 757251-59-5. Molecular formula: C13H12N2O3. Mole weight: 244.25. Catalog: APB757251595. | |
| Sorafenib Impurity 53 | Sorafenib Impurity 53. Uses: For analytical and research use. CAS No. 1209459-88-0. Molecular formula: C7H7BrN2O. Mole weight: 215.05. Catalog: APB1209459880. | |
| Sorafenib Impurity 5 (Regorafenib Impurity 5) | Sorafenib Impurity 5 (Regorafenib Impurity 5). Uses: For analytical and research use. CAS No. 320-51-4. Molecular formula: C7H5ClF3N. Mole weight: 195.57. Catalog: APB320514. | |
| Sorafenib Impurity 6 | Sorafenib Impurity 6. Uses: For analytical and research use. CAS No. 2204442-52-2. Molecular formula: C27H23N5O6. Mole weight: 513.51. Catalog: APB2204442522. | |
| Sorafenib Impurity 73 | Sorafenib Impurity 73. Uses: For analytical and research use. CAS No. 862875-16-9. Molecular formula: C21H17F3N4O4. Mole weight: 446.39. Catalog: APB862875169. | |
| Sorafenib Impurity 84 | Sorafenib Impurity 84. Uses: For analytical and research use. CAS No. 1403469-80-6. Molecular formula: C7H6Cl2N2O. Mole weight: 205.04. Catalog: APB1403469806. | |
| Sorafenib Impurity 85 | Sorafenib Impurity 85. Uses: For analytical and research use. CAS No. 1021077-12-2. Molecular formula: C7H6Cl2N2O. Mole weight: 205.04. Catalog: APB1021077122. | |
| Sorafenib Impurity 86 | Sorafenib Impurity 86. Uses: For analytical and research use. CAS No. 1793080-72-4. Molecular formula: C21H17F4N2O7P. Mole weight: 516.34. Catalog: APB1793080724. | |
| Sorafenib Impurity 87 | Sorafenib Impurity 87. Uses: For analytical and research use. CAS No. 24484-93-3. Molecular formula: C7H6ClNO2. Mole weight: 171.58. Catalog: APB24484933. | |
| Sorafenib Impurity 88 | Sorafenib Impurity 88. Uses: For analytical and research use. CAS No. 2004659-85-0. Molecular formula: C13H12N2O2. Mole weight: 228.25. Catalog: APB2004659850. | |
| Sorafenib Impurity G | Sorafenib Impurity G. Uses: For analytical and research use. Alternative Names: ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate. CAS No. 18585-06-3. Molecular formula: C10H9ClF3NO2. Mole weight: 267.63. Catalog: APB18585063. | |
| Sorafenib Impurity INT-1-B | Sorafenib Impurity INT-1-B. Uses: For analytical and research use. CAS No. 220000-87-3. Molecular formula: C7H7ClN2O. Mole weight: 170.6. Catalog: APB220000873. | |
| Sorafenib Impurity INT-1-F | Sorafenib Impurity INT-1-F. Uses: For analytical and research use. CAS No. 1065074-98-7. Molecular formula: C8H11N3O. Mole weight: 165.2. Catalog: APB1065074987. | |
| Sorafenib Impurity INT-1-N | Sorafenib Impurity INT-1-N. Uses: For analytical and research use. CAS No. 1863331-80-9. Molecular formula: C9H13N3O. Mole weight: 179.22. Catalog: APB1863331809. | |
| Sorafenib Impurity INT-1-O | Sorafenib Impurity INT-1-O. Uses: For analytical and research use. Molecular formula: C9H14N4O. Mole weight: 194.24. Catalog: APB09538. | |
| Sorafenib Impurity INT-2-G | Sorafenib Impurity INT-2-G. Uses: For analytical and research use. Molecular formula: C25H21N5O4. Mole weight: 455.47. Catalog: APB09539. | |
| Sorafenib Impurity INT-2-L | Sorafenib Impurity INT-2-L. Uses: For analytical and research use. CAS No. 864272-34-3. Molecular formula: C13H11N3O4. Mole weight: 273.25. Catalog: APB864272343. | |
| Sorafenib Impurity INT-2-M | Sorafenib Impurity INT-2-M. Uses: For analytical and research use. CAS No. 284462-80-2. Molecular formula: C12H11N3O2. Mole weight: 229.24. Catalog: APB284462802. | |
| Sorafenib Impurity INT-2-N | Sorafenib Impurity INT-2-N. Uses: For analytical and research use. Molecular formula: C13H11N3O4. Mole weight: 273.25. Catalog: APB09540. | |
| Sorafenib Impurity U | Sorafenib Impurity U. Uses: For analytical and research use. CAS No. 5470-22-4. Molecular formula: C6H4ClNO2. Mole weight: 157.55. Catalog: APB5470224. | |
| Sorafenib-methyl-d3 | Labeled Sorafenib, a potent Raf kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Sorafenib N-oxide | Sorafenib N-oxide. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] phenoxy] -N-methyl-2-pyridinecarboxamide 1-oxide. Grades: Highly Purified. CAS No. 583840-03-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H16ClF3N4O4. US Biological Life Sciences. | Worldwide |
| Sorafenib, p-Toluenesulfonate Salt | Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeting the ERK pathway and angiogenesis by targeting the receptor tyrosine kinases VEGFR-2 and PDGFR-b and their associated signaling cascades. Although sorafenib was initially developed as a Raf kinase inhibitor (IC50=6nM), it has since been shown to have activity against many receptor tyrosine kinases involved in tumorigenesis and angiogenesis including FGFR-1, wt BRAF and V599E mutant BRAF, as well as members of the so-called "split kinase" family: VEGFR-2, VEGFR-3, PDGFR-b, c-KIT, and Flt3. However, sorafenib is not active against erbB1, erbB2, ERK-1, MEK-1, EGFR, HER-2, IGFR-1, c-MET, c-yes, PKB, PKA, cdk1/cyclinB, PKC, and pim-1. In cellular mechanistic assays, sorafenib decreased basal phosphorylation of the ERK pathway in melanoma, breast, colon, and pancreatic tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 475207-59-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C21H16ClF3N4O3 C7H8O3S, Molecular Weight: 637.03. US Biological Life Sciences. | Worldwide |
| Sorafenib related compound 1 | Sorafenib related compound 1. Uses: For analytical and research use. CAS No. 2208275-83-4. Molecular formula: C8H6ClF3N2O. Mole weight: 238.59. Catalog: APB2208275834. | |
| Sorafenib related compound 10 | Sorafenib related compound 10. Uses: For analytical and research use. CAS No. 1012058-78-4. Molecular formula: C20H13ClF3N3O4. Mole weight: 451.79. Catalog: APB1012058784. | |
| Sorafenib related compound 11 | Sorafenib related compound 11. Uses: For analytical and research use. CAS No. 2004659-83-8. Molecular formula: C20H19N5O3. Mole weight: 377.4. Catalog: APB2004659838. | |
| Sorafenib related compound 12 | Sorafenib related compound 12. Uses: For analytical and research use. CAS No. 2004659-84-9. Molecular formula: C14H13N3O3. Mole weight: 271.28. Catalog: APB2004659849. | |
| Sorafenib related compound 13 | Sorafenib related compound 13. Uses: For analytical and research use. CAS No. 845306-04-9. Molecular formula: C7H7ClN2O. Mole weight: 170.6. Catalog: APB845306049. | |
| Sorafenib related compound 14 | Sorafenib related compound 14. Uses: For analytical and research use. CAS No. 284461-74-1. Molecular formula: C20H14ClF3N4O3. Mole weight: 450.8. Catalog: APB284461741. | |
| Sorafenib related compound 15 | Sorafenib related compound 15. Uses: For analytical and research use. CAS No. 284670-98-0. Molecular formula: C27H24N6O5. Mole weight: 512.53. Catalog: APB284670980. | |
| Sorafenib related compound 16 | Sorafenib related compound 16. Uses: For analytical and research use. CAS No. 1256817-30-7. Molecular formula: C8H10N2O2. Mole weight: 166.18. Catalog: APB1256817307. | |
| Sorafenib related compound 17 | Sorafenib related compound 17. Uses: For analytical and research use. CAS No. 88330-63-6. Molecular formula: C8H3ClF3NO. Mole weight: 221.56. Catalog: APB88330636. | |
| Sorafenib related compound 19 | Sorafenib related compound 19. Uses: For analytical and research use. CAS No. 1012058-77-3. Molecular formula: C12H10N2O3. Mole weight: 230.22. Catalog: APB1012058773. | |
| Sorafenib related compound 20 | Sorafenib related compound 20. Uses: For analytical and research use. CAS No. 1431697-81-2. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.83. Catalog: APB1431697812. | |
| Sorafenib related compound 21 | Sorafenib related compound 21. Uses: For analytical and research use. Molecular formula: C13H13N3O2. Mole weight: 243.27. Catalog: APB09542. | |
| Sorafenib related compound 22 | Sorafenib related compound 22. Uses: For analytical and research use. CAS No. 284462-89-1. Molecular formula: C15H17N3O2. Mole weight: 271.32. Catalog: APB284462891. | |
| Sorafenib related compound 23 | Sorafenib related compound 23. Uses: For analytical and research use. CAS No. 284462-37-9. Molecular formula: C13H13N3O2. Mole weight: 243.27. Catalog: APB284462379. | |
| Sorafenib related compound 24 | Sorafenib related compound 24. Uses: For analytical and research use. Molecular formula: C17H20F3N3O3. Mole weight: 371.36. Catalog: APB09543. | |
| Sorafenib related compound 25 | Sorafenib related compound 25. Uses: For analytical and research use. CAS No. 1261456-08-9. Molecular formula: C8H4F3NO2. Mole weight: 203.12. Catalog: APB1261456089. | |
| Sorafenib related compound 26 | Sorafenib related compound 26. Uses: For analytical and research use. CAS No. 573673-43-5. Molecular formula: C21H15ClF3N3O4. Mole weight: 465.81. Catalog: APB573673435. | |
| Sorafenib related compound 27 | Sorafenib related compound 27. Uses: For analytical and research use. CAS No. 6144-78-1. Molecular formula: C7H8N2O. Mole weight: 136.15. Catalog: APB6144781. | |
| Sorafenib related compound 28 | Sorafenib related compound 28. Uses: For analytical and research use. Molecular formula: C13H13N3O2. Mole weight: 243.27. Catalog: APB09545. | |
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