A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize ADC Tusamitamab ravtansine (SAR408701) (HY-P99542)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR-408377; PF-08046050 Antibody; SAR445953 Antibody. CAS No. 2349294-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99054.
Tusamitamab ravtansine
Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5, composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAR-408701; HuMAb2-3-SPDB-DM4. CAS No. 2254086-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99542.
Tuspetinib
Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC50s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HM43239. CAS No. 2294874-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145015.
Tussilagone
Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 104012-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1388.
Tussilagone
Tussilagone. Group: Biochemicals. Alternative Names: Farfaratin. Grades: Plant Grade. CAS No. 104012-37-5. Pack Sizes: 10mg. Molecular Formula: C23H34O5, Molecular Weight: 390.512999999999. US Biological Life Sciences.
Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M1774; ATR inhibitor 1. CAS No. 1613200-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111451.
Tuxobertinib
Tuxobertinib (BDTX-189) is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. Tuxobertinib shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BDTX-189. CAS No. 2414572-47-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136789.
TVB-3166
TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1533438-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120394.
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2097262-58-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120062.
TW-37
TW-37 is a potent Bcl-2 inhibitor with Ki values of 260, 290 and 1110 nM for Mcl-1, Bcl-2 and Bcl-xL, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 877877-35-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12020.
Tween 20
250ml Pack Size. Group: Detergents. Formula: N/A. CAS No. 9005-64-5. Prepack ID 18945167-250ml. See USA prepack pricing.
Tween 20
1lt Pack Size. Group: Detergents. Formula: N/A. CAS No. 9005-64-5. Prepack ID 18945167-1lt. See USA prepack pricing.
Tween-20 is a polysorbate surfactant whose stability and relative non-toxicity allow it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications. It is a polyoxyethylene derivative of sorbitan monolaurate, and is distinguished from the other members in the Tween range by the length of the polyoxyethylene chain. The commercial product contains a range of chemical species.Biological Applications:Tween 20 has a broad range of applications. For example, it is used: to stabilize purified protein derivative (PPD) solution, used in skin testing for tuberculosis exposure, as a blocking agent in immunologic assays, such as Western blots and ELISA and as a solubilizing agent of membrane proteins for lysing mammalian cells, at a concentration of 0.05 to 0.5%.CAS No:9005-64-5. Group: Biochemicals. Alternative Names: Polysorbate 20; Polyethylene glycol sorbitan monolaurate. Grades: Molecular Biology Grade. CAS No. 9005-64-5. Pack Sizes: 100ml, 500ml, 1L, 4L, 10L. US Biological Life Sciences.
Tween 60, also known as polysorbate 60, polyoxyethylene sorbitan monostearate, its molecular formula is C64H126O26. In general, it is a lemon-colored to orange oily liquid or semi-gel, with a slight special odor and a slightly bitter taste. Tween 60 is soluble in water, aniline, ethyl acetate and toluene, but insoluble in mineral oil and vegetable oil. Tween 60 has excellent emulsifying properties, and has the functions of wetting, foaming, and diffusion, and is widely used in textiles, medicine, water-based coatings and other industries. Alternative Names: Polyoxyethylene-60-sorbitan monostearate. CAS No. 9005-67-8. Molecular formula: C64H126O26. Mole weight: 1311.70. IUPAC Name: [(2R)-2-[(2R,3R,4S)-3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-hydroxyethyl] dodecanoate. InChI: InChI=1S/C22H42O8/c1-2-3-4-5-6-7-8-9-10-11-20(26)29-16-18(25)21-22(28-15-13-24)19(17-30-21)27-14-12-23/h18-19,21-25H,2-17H2,1H3/t18-,19+,21-,22-/m1/s1.
Tween-61
Tween-61.
Tween 65
Tween 65. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1Kg, 500g, 5Kg. US Biological Life Sciences.
1lt Pack Size. Group: Detergents. Formula: C64H124O26. CAS No. 9005-65-6. Prepack ID 90004890-1lt. Molecular Weight 1310. See USA prepack pricing.
Tween 80
Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Polysorbate 80. CAS No. 9005-65-6. Pack Sizes: 50 mL; 100 mL. Product ID: HY-Y1891.
Tween 80
Tween 80 is a polysorbate surfactant used for selective protein extraction and the isolation of nuclei from mammalian cell lines. Tween 80 has been used in drug vehicle solutions for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells. Group: Inhibitors. Alternative Names: Polysorbate 80. CAS No. 9005-65-6. Pack Sizes: 100mL. Product ID: S6702. Smiles: CCCCCCCCC=CCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO. Storage Conditions: 2 years room temperature liquid.
TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells. Group: Biochemicals. Alternative Names: POE (20) sorbitan monooleate; Polyethylene glycol sorbitan monooleate; Polyoxyethylene sorbitan monooleate; Polysorbate 80. Grades: Molecular Biology Grade. CAS No. 9005-65-6. Pack Sizes: 100ml, 500ml, 1L, 4L. US Biological Life Sciences.
TWS119 is an inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway. Uses: Scientific research. Category: Signaling pathways. CAS No. 601514-19-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10590.
TWS 119
TWS 119. Group: Biochemicals. Grades: Purified. CAS No. 1507095-58-0. Pack Sizes: 10mg. US Biological Life Sciences.
A potent inhibitor of GSK-3 β (Glycogen synthase kinase-3 β) (IC50 = 30 nM). At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. Group: Biochemicals. Alternative Names: 3-[[6-(3-Aminophenyl)-1H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol. Grades: Highly Purified. CAS No. 601514-19-6. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
TX1-85-1
TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1603845-32-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100848.
TXNIP-IN-1
TXNIP-IN-1 is TXNIP-TRX (thioredoxin-interacting protein- thioredoxin) complex inhibitor extracted from patent US20200085800A1, Compound 1. TXNIP-IN-1 can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1268955-50-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-115688.
TX Polymer
TX Polymer.
TY 52156
TY 52156. Group: Biochemicals. Grades: Purified. CAS No. 934369-14-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TY-52156
TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 934369-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19736.
TYA-018
TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor. TYA-018 can protect heart function in mice. TYA-018 also enhances energetics in mice by increasing expression of targets associated with fatty acid metabolism, protein metabolism, and oxidative phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2653254-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153392.
TYD-68
TYD-68 is a highly efficient and selective CRBN-recruited TYK2 PROTAC degrader with a DC50 value of 0.42 nM. TYD-68 significantly inhibits IL-12 and IFN-α-induced STAT4 and STAT1 phosphorylation, thereby blocking TYK2-dependent signaling pathways.TYD-68 can be used in the study of psoriasis. (Pink: Target protein ligand (HY-173359); Black: Linker (HY-W007732B); Blue: E3 ligase ligand (HY-14658); E3 ligase ligand + Linker (HY-173358))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3110703-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173357.
Tyk2-IN-19
Tyk2-IN-19 (Compound 1) is an orally active and blood-brain barrier (BBB) permeable Tyk2 inhibitor. Tyk2-IN-19 can be used for study of neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2866415-98-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161683.
tylactone mycaminosyltransferase
The enzyme participates in the biosynthetic pathway of the macrolide antibiotic tylosin, which is produced by several species of Streptomyces bacteria. Activity is significantly enhanced by the presence of an accessory protein encoded by the tylM3 gene. Group: Enzymes. Synonyms: tylM2 (gene name). Enzyme Commission Number: EC 2.4.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2552; tylactone mycaminosyltransferase; EC 2.4.1.316; tylM2 (gene name). Cat No: EXWM-2552.
Tylopeptin A
Tylopeptin A is originally isolated from Tylopilus neofelleus and it has anti-gram-positive bacteria activity. Molecular formula: C73H120N18O19. Mole weight: 1553.84.
Tylopeptin B
Tylopeptin B is originally isolated from Tylopilus neofelleus and it has anti-gram-positive bacteria activity. Molecular formula: C72H118N18O19. Mole weight: 1539.81.
Tylosin
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1401-69-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0519A.
Tylosin
Tylosin is a 16-member-ring macrolide produced through the fermentation of Streptomyces fradiae, a species of actinobacteria found in soil. It is effective against gram-positive bacteria, Mycoplasma species and certain gram-negative bacteria. With other macrolides, tylosin inhibits protein synthesis by binding to the 50S subunit of the bacterial ribosome and disrupting aminoacyl-and peptidyl-tRNA transcription. This is believed to ultimately prevent the bacteria from reproducing. Synonyms: Tylosine; Tylocine; Tylosinum; Fradizine; NSC758961; (10E,12E)-(3R,4S,5S,6R,8R,14S,15R)-14-((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxymethyl)-5-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-3-dimethylamino-beta-D-glucopyranosyl)oxy)-6-formylmethyl-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide. Grade: >98%. CAS No. 1401-69-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
A highly purified form of tylosin A. It is a macrolide antibiotic, which is considered to be the major component of tylosin (comprises approximately 90% of tylosin). However, tylosins B, C and D contribute to the overall potency of tylosin. Synonyms: Tylosin; [4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15R*,16R*)]-15-[[(6-Deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-4-hydroxy-5,9,13-trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7-acetaldehyde; Fradizine; Tylocine; Tylosine. Grade: ≥99.0% by HPLC. CAS No. 8026-48-0. Molecular formula: C46H77NO17. Mole weight: 916.10.
Tylosin B
It is a 16-membered macrolide antibiotic and a metabolite of Tylosin. It is also a precursor of Tilmicosin. Synonyms: Desmycosin; 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tylosin; Demycarosyltylosin. Grade: ≥95.0% by HPLC. CAS No. 11032-98-7. Molecular formula: C39H65NO14. Mole weight: 771.93.
Tylosin monotartrate
Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. It can be used to prevent and treat respiratory diseases such as mycoplasma pneumonia, pleuropneumonia, swine pneumonia, Haemophilus parasuis, streptococcus suis, and other tissue infections. Synonyms: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt); Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin tartrate. Grade: >98%. CAS No. 74610-55-2. Molecular formula: C50H83NO23. Mole weight: 1066.19.
Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 74610-55-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0519.
Tylosin tartrate
25g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C49H81NO23. CAS No. 74610-55-2. Prepack ID 12004989-25g. Molecular Weight 1052.16. See USA prepack pricing.
Tylosin tartrate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C49H81NO23. CAS No. 74610-55-2. Prepack ID 12004989-5g. Molecular Weight 1052.16. See USA prepack pricing.
Tylosin tartrate
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C46H77NO17 ¢C4H4O6. CAS No. 1405-54-5. Prepack ID 90028737-1g. Molecular Weight 1066.19. See USA prepack pricing.
Tylosin Tartrate
Tylosin Tartrate is a macrolide antibiotic isolated from a strain of Streptomycetes fradiae found in soil from Thailand. Antibacterial. Group: Biochemicals. Alternative Names: Tylosin (2R,3R)-2,3-dihydroxybutanedioate (1:1) (Salt; Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (Salt); Oxacyclohexadecane Tylosin deriv.; Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin Tartrate. Grades: Highly Purified. CAS No. 74610-55-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C??H??NO??, Molecular Weight: 1066.19. US Biological Life Sciences.
Worldwide
Tylosin Tartrate
Tylosin Tartrate. CAS No. 74610-55-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals[1][2]. Uses: Scientific research. Category: Induced disease models products. CAS No. 25301-02-4. Pack Sizes: 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-B1068.
Tyloxapol, USP
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent[citation needed] (containing mucus and pus) bronchopulmonary secretions,[1][2] administered by inhalation through a nebulizer[3] or with a stream of oxygen. With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.[4] Tyloxapol is the main active ingredient of the medical device Tacholiquin®. Tacholiquin® is an expectorant designated for inhalation and instillation reaching the upper and lower airways. Group: Biochemicals. Alternative Names: p- (1, 1, 3, 3-Tetramethylbutyl) Phenol Polymer with Ethylene Oxide and Formaldehyde; Ethylene Oxide Polymer with Formaldehyde and p- (1, 1, 3, 3-Tetramethylbutyl) phenol; Oxirane Polymer with Formaldehyde and 4- (1, 1, 3, 3-tetramethylbutyl) phenol; Ethylene oxide-formaldehyde-4- (1, 1, 3, 3-tetramethylbutyl) phenol copolymer; Ethylene oxide-formaldehyde-p-octylphenol Copolymer; NSC 90255; Superinone; Triton A 20; Triton WR 1339; Tyloxapol; p-Isooctyl polyoxyethyl ene phenol Formaldehyde Polymer. Grades: USP. CAS No. 25301-02-4. Pack Sizes: 1g, 5g, 25g. Molecular Formula: (C17H30O4)n, Molecular Weight: As reported. US Biological Life Sciences.