A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Tungstosilicic acid hydrate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
Tunicamycin
N-linked glycosylation is a highly regulated post-translational modification that is involved in protein folding and conformation, oligomerization, sorting, cell-cell interactions, and targeting of proteins to sub- or extra-cellular locations. It is initiated in the endoplastic reticulum with the transfer of a carbohydrate moiety to an asparagine residue within a specific amino acid consensus sequence and then further processed in the Golgi whereupon a mature glycoprotein is exported through the secretory machinery to the plasma membrane. Tunicamycin, a mixture of nucleoside antibiotics, is a specific inhibitor of N-linked glycoslylation that blocks the first step of glycoprotein synthesis thereby inducing protein unfolding. At 500 nM, it can impair the function of several receptor tyrosine kinases, including EGFR, ErbB2, ErbB3, and IGF-IR.1 Also at 500 nM, it radiosensitizes U251 glioma and BXPC3 pancreatic adenocarcinoma cells to chemotherapy.1 Tunicamycin impairs ALK phosphorylation Group: Biochemicals. Alternative Names: Streptomyces Iysosuperficus. Grades: Molecular Biology Grade. CAS No. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C39H64N4O16, Molecular Weight: 844.4. US Biological Life Sciences.
Worldwide
Tunicamycin
Tunicamycin, a mixture of homologous nucleoside antibiotics, has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells. Tunicamycin blocks the formation of N-glycosidic linkages by inhibiting the first step in glycoprotein synthesis. It exhibits a range of biological activities, including antimicrobial, antivirus, and antitumor effects. It is produced by certain bacteria, including Streptomyces lysosuperficus and Streptomyces chartreusis. Grade: ≥98%. CAS No. 11089-65-9.
Tunicamycin
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity.Tunicamycin increases exosome release in cervical cancer cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: tunicamycin, Tunicamycin A1, CID5607, 11089-65-9. Product Category: Inhibitors. Appearance: White to off-white powder. CAS No. 11089-65-9. Molecular formula: C37H60N4O16. Mole weight: 816.89. Purity: 98%+. IUPACName: N-[2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[2-[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-4,5-dihydroxyoxan-3-yl]-12-methyltridec-2-enamide. Canonical SMILES: CC(C)CCCCCCCCC=CC(=O)NC1C(C(C(OC1OC2C(C(C(C(O2)CO)O)O)NC(=O)C)CC(C3C(C(C(O3)N4C=CC(=O)NC4=O)O)O)O)O)O. Density: 1.57g/cm³. Product ID: ACM11089659. Alfa Chemistry ISO 9001:2015 Certified.
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity[1][2][3].Tunicamycin increases exosome release in cervical cancer cells[4]. Uses: Scientific research. Group: Natural products. CAS No. 11089-65-9. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-A0098.
Tunicamycin D
Tunicamycin D is a member of the tunicamycin group of nucleoside antibiotics, which are known for their antibacterial, antiviral, and antitumor activities. These activities are primarily due to the inhibition of bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY), an enzyme crucial for the biosynthesis of peptidoglycan, which is a major component of bacterial cell walls. Tunicamycins also inhibit the human enzyme UDP-N-acetylglucosamine-dolichyl phosphate N-acetylglucosamine-phosphotransferase (GPT), which is involved in the first step of N-linked glycosylation of proteins in the endoplasmic reticulum. This inhibition can lead to the prevention of N-glycan attachment to proteins, affecting their proper folding, trafficking, and function, and ultimately inducing cellular stress and apoptosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(11S)-11-O-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl]-6,10-dideoxy-10-[[(2E)-15-methyl-1-oxo-2-hexadecen-1-yl]amino]-L-galacto-β-D-allo-undecodialdo-1,4-furanose-11,7-pyranos-1-yl]-; 1-[(11S)-11-O-[2-(Acetylamino)-2-deoxy-α-D-glucopyranosyl]-6,10-dideoxy-10-[[(2E)-15-methyl-1-oxo-2-hexadecen-1-yl]amino]-L-galacto-β-D-allo-undecodialdo-1,4-furanose-11,7-pyranos-1-yl. Grade: ≥95%. CAS No. 66081-38-7. Molecular formula: C40H66N4O16. Mole weight: 858.98.
Tunicamycin Ready Made Solution
5 mg/mL in DMSO, from Streptomyces sp. Group: Fluorescence/luminescence spectroscopy.
Tunlametinib
Tunlametinib, an antineoplastic agent, is a MEK1/2 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HL-085. CAS No. 1801756-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132844.
Tupichinol A
Tupichinol A is a natural compound isolated from the underground parts of Tupistra chinensis. Synonyms: (2R,3R)-2-(4-hydroxyphenyl)-7-methoxy-8-methyl-3,4-dihydro-2H-chromen-3-ol. Grade: 98.5%. CAS No. 497142-88-8. Molecular formula: C17H18O4. Mole weight: 286.32.
Turanose
Turanose is an isomer of Sucrose that naturally exists in honey. Turanose has anti-inflammatory and regulates adipogenesis effect. Turanose has potential for obesity and related chronic diseases research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 547-25-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113334.
Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor ( EcR ) agonist in some insect systems [1]. Uses: Scientific research. Group: Natural products. CAS No. 41451-87-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2548.
Turmeric
This exotic root plant is spicy and vibrant and perfectly targets discoloration to smooth out scars and hyperpigmentation. Pack Sizes: 1 kg. Product ID: CDC10-0554. Category: Anti-Acne Ingredients. Product Keywords: Cosmetic Ingredients; Active Ingredients; Anti-Acne Ingredients; Turmeric; CDC10-0554.
Turmeric Extract
Turmeric extract is prepared from curcuma longa of the ginger family, which native to India, China. Turmeric extract also known as curcuma longa extract are taken from the rhizome, which has a characteristic bright yellow color, the active ingredien of turmeric extract is curcumin, which has the function of reducing blood fat, resisting tumor, anti-inflammatory and cholagogic and antioxidant effects. Group: Others. Mole weight: 368.38. Turmeric Extract; Curcuma Longa Linn. Cat No: EXTC-022.
Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FXR-450; XL335; WAY-362450. CAS No. 629664-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50911.
Turpentine Oil
Turpentine Oil. CAS No. 8006-64-2. FEMA No. 3089. Kosher: Y. VIGON Item # 504263. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Turpentine Oil
Turpentine Oil. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
California
TURPENTINE OIL
TURPENTINE OIL. Group: Polymers. CAS No. 8006-64-2.
Turpentine Oil BP/ EP
Turpentine Oil BP/ EP. CAS No. 8006-64-2.
Tusamitamab
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2349294-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99054.
Tusamitamab ravtansine
Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5 , composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8 [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR-408701; HuMAb2-3-SPDB-DM4. CAS No. 2254086-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99542.
Tuspetinib
Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM43239. CAS No. 2294874-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145015.
Tussilagone
Tussilagone. Group: Biochemicals. Alternative Names: Farfaratin. Grades: Plant Grade. CAS No. 104012-37-5. Pack Sizes: 10mg. Molecular Formula: C23H34O5, Molecular Weight: 390.512999999999. US Biological Life Sciences.
Worldwide
Tutin
Tutin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tutu; Toot poison. Appearance: crystalline. CAS No. 2571-22-4. Molecular formula: C15H18O6. Mole weight: 294.3. Purity: 0.98. IUPACName: Tutin. Canonical SMILES: CC(=C)C1C2C(C3(C4(CO4)C5C(C3(C1C(=O)O2)O)O5)C)O. Density: 1.52g/cm³. Product ID: ACM2571224. Alfa Chemistry ISO 9001:2015 Certified.
Tuvusertib
Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a K i value below 1 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M1774; ATR inhibitor 1. CAS No. 1613200-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111451.
TVB-3166
TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1533438-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120394.
TW 37. Group: Biochemicals. Grades: Purified. CAS No. 877877-35-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TW-37
TW-37 is a potent Bcl-2 inhibitor with K i values of 260, 290 and 1110 nM for Mcl-1 , Bcl-2 and Bcl-xL , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 877877-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12020.
TWEAK Receptor human
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
1lt Pack Size. Group: Detergents. Formula: N/A. CAS No. 9005-64-5. Prepack ID 18945167-1lt. See USA prepack pricing.
Tween 20
Tween 20. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Polysorbate 20; Polyethylene glycol sorbitan monolaurate. Product Category: Non-ionic Surfactants. Appearance: Viscous amber liquid. CAS No. 9005-64-5. Molecular formula: C58H114O26. Mole weight: 1228. IUPACName: 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate. Density: 1.11 g/mL at 20 °C. ECNumber: 500-018-3. Product ID: ACM9005645. Alfa Chemistry ISO 9001:2015 Certified.
Tween 20
250ml Pack Size. Group: Detergents. Formula: N/A. CAS No. 9005-64-5. Prepack ID 18945167-250ml. See USA prepack pricing.
Tween 20
Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polysorbate 20. CAS No. 9005-64-5. Pack Sizes: 100 mL. Product ID: HY-141415.
Tween-20 is a polysorbate surfactant whose stability and relative non-toxicity allow it to be used as a detergent and emulsifier in a number of domestic, scientific, and pharmacological applications. It is a polyoxyethylene derivative of sorbitan monolaurate, and is distinguished from the other members in the Tween range by the length of the polyoxyethylene chain. The commercial product contains a range of chemical species.Biological Applications:Tween 20 has a broad range of applications. For example, it is used: to stabilize purified protein derivative (PPD) solution, used in skin testing for tuberculosis exposure, as a blocking agent in immunologic assays, such as Western blots and ELISA and as a solubilizing agent of membrane proteins for lysing mammalian cells, at a concentration of 0.05 to 0.5%.CAS No:9005-64-5. Group: Biochemicals. Alternative Names: Polysorbate 20; Polyethylene glycol sorbitan monolaurate. Grades: Molecular Biology Grade. CAS No. 9005-64-5. Pack Sizes: 100ml, 500ml, 1L, 4L, 10L. US Biological Life Sciences.