A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Xeruborbactam disodium | Xeruborbactam disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170848-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136072. |  |
| Xestospongin C | Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca2+ release from cerebellar microsomes with an IC50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca2+ signaling in neuronal and nonneuronal cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (-)-Xestospongin C. CAS No. 88903-69-9. Pack Sizes: 10 μg. Product ID: HY-103312. | |
| Xevinapant | Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs, and it binds to XIAP, cIAP1, and cIAP2 proteins with Ki of 66.4, 1.9, and 5.1 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-406; Debio 1143; SM-406. CAS No. 1071992-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15454. | |
| Xevinapant | Xevinapant Inhibitor. Uses: Scientific use. Product Category: T6763. CAS No. 1071992-99-8. |  |
| Xevinapant hydrochloride | Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with Kis of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-406 hydrochloride; Debio 1143 hydrochloride; SM-406 hydrochloride. CAS No. 1071992-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13208. | |
| XG 102 | XG-102 is a TAT-conjugated dextrose peptide that inhibits c-Jun N-terminal kinase, and has the potential to treat intraocular inflammation. Alternative Names: AM 111; XG 102 peptide; D-JNKI-1. CAS No. 1198367-70-2. Molecular formula: C164H285N65O41. Mole weight: 3823.49. |  |
| X-Gal | X-Gal is a fluorecent substrate for β-galactosidase and blue-white selection of recombinant bacterial colonies with the lac+ genotype. Alternative Names: 5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside; X-b-D-Galactoside; BCIG. CAS No. 7240-90-6. Molecular formula: C14H15BrClNO6. Mole weight: 408.64. | |
| X-GAL | X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCIG. CAS No. 7240-90-6. Pack Sizes: 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15934. | |
| X-Gal, 40mg/ml in DMF (5-Bromo-4-chloro-3-indolyl-b-D-galactoside galactopyranoside, Xgal) | Blue substrate used in the detection of b-galactosidase in bacteria or phage as a selection agent for cloning experiments utilizing the lacZ vector. Colonies expressing b-galactosidase will appear blue in the presence of XGAL. Others will appear white. Group: Biochemicals. Alternative Names: 5-Bromo-4-chloro-3-indolyl-ß-D-galactoside (galactopyranoside) in Dimethylformamide. Grades: Molecular Biology Grade. CAS No. 7240-90-6,68-12-2. Pack Sizes: 10ml, 5x10ml. Molecular Formula: C14H15BrClNO6 DMF, Molecular Weight: 408.61. US Biological Life Sciences. |  Worldwide |
| X-Gal (5-Bromo-4-chloro-3-indolyl-b-D-galactoside galactopyranoside, Xgal) | Blue substrate used in the detection of b-galactosidase in bacteria or phage as a selection agent for cloning experiments utilizing the lacZ vector. Colonies expressing b-galactosidase will appear blue in the presence of XGAL. Others will appear white.Gene Cloning:In gene cloning, X-gal is used as a visual indication of whether a cell expresses a functional β-galactosidase enzyme in a technique called blue/white screening. This method of screening is a convenient way of distinguishing a successful cloning product from other unsuccessful ones.The blue/white screening method relies on the principle of α-complementation of the β-galactosidase gene, where a fragment of the lacZ gene (lacZα) in the plasmid can complement another mutant lacZ gene (lacZΔM15) in the cell. Both genes by themselves produce non-functional peptides, however, when expressed together, as when a plasmid containing lacZα is transformed into a lacZΔM15 cells, they form a functional β-galactosidase. The presence of an active β-galactosidase may be detected when cells are grown in plates containing X-gal, the blue-colored product precipitated within cells resulted in the characteristic blue colonies. However, the multiple cloning site, where a gene of interest may be ligated into the plasmid vector, is located within the lacZα gene. Group: Bioc | Worldwide |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 5g Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-5g. Molecular Weight 408.63. See USA prepack pricing. |  |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 100mg Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-100mg. Molecular Weight 408.63. See USA prepack pricing. | |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 1g Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-1g. Molecular Weight 408.63. See USA prepack pricing. | |
| X-Gal (aka X-b-D-galactoside) | X-Gal (aka X-b-D-galactoside). CAS No. 7240-90-6. Categories: x-gal. |  Pennsylvania PA |
| X-GAL (solution) | X-GAL (BCIG) (solution) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity[1][2].Solvent and Concentration: DMF: 20 mg/mL. Uses: Scientific research. Category: Signaling pathways. CAS No. 7240-90-6. Pack Sizes: 5 mL. Product ID: HY-DY2002. | |
| x-Gluc | Gluc. CAS No. 18656-96-7. | Pennsylvania PA |
| X-Gluc | X-Gluc. CAS No. 18656-96-7. | Pennsylvania PA |
| XIAP degrader-1 | XIAP degrader-1, a primary amine tethered small molecule, promotes the degradation of X-linked inhibitor of apoptosis protein (XIAP). Uses: Scientific research. Category: Signaling pathways. CAS No. 2803617-91-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115865. | |
| XIE62-1004-A | XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2421146-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W688687. | |
| Ximelagatran | Ximelagatran, an ester prodrug of melagatran, with anticoagulant effect, is the first member of direct thrombin inhibitors that can be taken orally. Uses: An orally active direct thrombin inhibitor; prodrug of melagatran. antithrombotic. Alternative Names: H 376-95; H 376/95; H 37695; H-37695; H37695; N-[(1R)-1-Cyclohexyl-2-[(2S)-2-[[[[4-[(hydroxyamino)iminomethyl]phenyl]methyl]amino]carbonyl]-1-azetidinyl]-2-oxoethyl]glycine Ethyl Ester; Exanta; H 376/95. Grades: >98%. CAS No. 192939-46-1. Molecular formula: C24H35N5O5. Mole weight: 473.57. | |
| Ximelagatran | Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: H 376/95. CAS No. 192939-46-1. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10787. | |
| Ximelagatran | An orally active direct thrombin inhibitor; prodrug of Melagatran. Antithrombotic. Group: Biochemicals. Alternative Names: N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine Ethyl Ester; Exanta; H 376/95. Grades: Highly Purified. CAS No. 192939-46-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ximeninic acid | Ximeninic acid. Alternative Names: (E)-octadec-11-en-9-ynoic acid. CAS No. 557-58-4. Purity: >95.0%. Product ID: FFC-AR-557584. Molecular formula: C18H30O2. Mole weight: 278.43. IUPAC Name: (E)-octadec-11-en-9-ynoic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Xipamide | Xipamide is a diuretic and antihypertensive agent. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide; Aquaphor; Chronexan; Diurex; Lumitens. Grades: Highly Purified. CAS No. 14293-44-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Xipamide-d6 | A labeled diuretic and antihypertensive. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide-d6; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide-d6; Aquaphor-d6; Chronexan-d6; Diurex-d6; Lumitens-d6. Grades: Highly Purified. CAS No. 1330262-09-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Xipamide impurity 1 | Xipamide impurity 1. Uses: For analytical and research use. CAS No. 14665-31-7. Molecular formula: C7H4Cl2O5S. Mole weight: 271.06. Catalog: APB14665317. |  |
| XIRAN Heatboosters | XIRAN Heatboosters. |  |
| Xirestomig | Xirestomig (ATG-101) is a tetravalent "2+2" PD-L1×4-1BB bispecific antibody. Xirestomig binds PD-L1 and 4-1BB concurrently, with a greater affinity for PD-L1, and potently activated 4-1BB+ T cells when cross-linked with PD-L1-positive cells. Xirestomig activates exhausted T cells upon PD-L1 binding. Xirestomig displays potent antitumor activity in numerous in vivo tumor models, including those resistant or refractory to immune checkpoint inhibitors (ICIs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATG-101. CAS No. 2756879-35-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990778. | |
| XJ735 | XJ735, a RGD peptidomimetic αVβ3 integrin antagonist, contains anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. Alternative Names: XJ 735; XJ-735; Cyclo[L-alanyl-L-arginylglycyl-L-α-aspartyl-3-(aminomethyl)benzoyl]; 3,6,9,12,15-Pentaazabicyclo[15.3.1]heneicosa-1(21),17,19-triene-5-acetic acid, 11-[3-[(aminoiminomethyl)amino]propyl]-14-methyl-4,7,10,13,16-pentaoxo-, (5S,11S,14S)-. Grades: ≥95%. CAS No. 153381-95-4. Molecular formula: C23H32N8O7. Mole weight: 532.55. | |
| XJB-5-131 | XJB-5-131 is a mitochondria-targeted ROS and electron scavenger[1]. XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria[2]. XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs)[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 866404-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-129460. | |
| XK-101-2 | XK-101-2 is a nucleoside antibiotic isolated from Micromonospora chalcea subsp. It exhibits activity against Mycobacterium phlei and gram-positive bacteria. Molecular formula: C11H13N3O5. Mole weight: 267.24. | |
| XK-90 | XK-90 is produced by Streptomyces sp. It is active against Gram-positive and Gram-negative bacteria. Alternative Names: Antibiotic XK 90; 5-(2-Acetylhydrazino)salicylaldehyde. CAS No. 61172-42-7. Molecular formula: C9H10N2O3. Mole weight: 194.19. | |
| XL01126 | XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)) composed of the VHL ligand VH 101, thiol (HY-47851, blue part) and the LRRK2 inhibitor HG-10-102-01 (HY-13488, red part). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3011029-58-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148030. | |
| XL041 | XL041 (BMS-852927) is an LXRβ-selective agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-852927. CAS No. 1256918-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101973. | |
| XL092 | XL092 is a novel oral multi-targeted inhibitor of receptor tyrosine kinases MET, VEGFR2, and TAM kinases (AXL, MER), which play important roles in tumor growth, vascularization, resistance to therapy and in modulating the tumor immune microenvironment. Alternative Names: JUN04542; XL-092; XL 092. CAS No. 2367004-54-2. Molecular formula: C29H25FN4O5. Mole weight: 528.53. | |
| XL177A | XL177A is a covalent USP7 inhibitor that blocks the deubiquitinase activity of USP7. XL177A destabilizes non-canonical PRC1 complexes or KDM6A and reduces chromatin deposition of H2AK119Ub, thereby relieving the repression of neuronal differentiation programs. Meanwhile, XL177A also regulates the ELOF1-UVSSA-USP7-nuclear β-catenin axis, decreasing the transcription levels of related proteins and the accumulation of nuclear β-catenin. XL177A exerts antiviral effects by reducing the expression levels of coronavirus receptors, and exhibits inhibitory activity against APC-mutated colorectal cancer cells, neuroblastoma, and coronaviruses including SARS-CoV-2 variants. XL177A is mainly used in studies related to colorectal cancer, neuroblastoma, and coronavirus infections[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417089-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138794. | |
| XL 184 | XL 184. Group: Biochemicals. Grades: Purified. CAS No. 849217-68-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL228 | XL228 is a multi-targeted tyrosine kinase inhibitor with IC50s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src and Lyn, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 898280-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15749. | |
| XL-3158 | XL-3158 is a selective and cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor (IC50: 11.1 μM for human cGAS, 2.19 μM for mouse cGAS). XL-3158 simultaneously occupy allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation and thereby attenuating the cGAS-DNA interactions. XL-3158 inhibits cGAS by targeting phase separation. XL-3158 efficiently penetrates cells by inhibiting aggregate formation, effectively reducing the local concentration of cGAS within cells. XL-3158 can be used for the study of cGAS-dependent inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117797-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-174802. | |
| XL388 | XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2. Uses: Scientific research. Category: Signaling pathways. CAS No. 1251156-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13806. | |
| XL 388 | XL 388. Group: Biochemicals. Grades: Purified. CAS No. 1251156-08-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL413 | XL413 is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-863233. CAS No. 1169558-38-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15260. | |
| XL 413 hydrochloride | XL 413 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1169562-71-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL413 monohydrochloride | XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-863233 monohydrochloride. CAS No. 2062200-97-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15260A. | |
| XL-647 | XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits EGFR, HER2, VEGFR and EphB4 kinase. Alternative Names: XL-647; XL 647; XL647; EXEL-7647; EXEL 7647; EXEL7647; KD-019; KD 019; KD019. Grades: >98%. CAS No. 781613-23-8. Molecular formula: C24H25Cl2FN4O2. Mole weight: 491.39. | |
| XL 765 | XL 765 is a PI3K inhibitor used for the treatment of cancers. It also suppresses DNA-PK and mTOR. Alternative Names: XL765-II; XL765 II; XL765II; XL 765-II; XL-765-II; SAR 245409; SAR245409; SAR-245409; N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide; N-(4-(N-(3-((3,5-Dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide. CAS No. 1349796-36-6. Molecular formula: C31H29N5O6S. Mole weight: 599.662. | |
| XL-784 | XL-784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1224964-36-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19485. | |
| XL888 | XL888 is a potent and orally active HSP90 inhibitor with an IC50 value of 24 nM. XL888 shows anti-proliferation activity and induces Apoptosis. XL888 shows anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1149705-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13313. | |
| XLFG xyloglucan oligosaccharide | XLFG xyloglucan oligosaccharide. Alternative Names: XLFG. Molecular formula: C57H96O47. Mole weight: 1533.3. | |
| XM462 | XM462 is a dihydroceramide desaturase inhibitor. XM462 produced a mixed-type inhibition (Ki=2 μM) in vitro. XM462 has dihydroceramide desaturase inhibition both in vitro and in cultured cells with IC50 values of 8.2 and 0.78 μM, respectively. XM462 can be used for the research of tumor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1045857-53-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-135818. | |
| XmAb 5592 | XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1221901-33-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99381. | |
| Xma I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus -2 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme 95% of the dna fragments can be ligated. of these 90% can be recut. Group: Restriction Enzymes. Purity: 300U;1500U. C↑CCGGG GGGCC↓C. Activity: 3000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene XmaI from Xanthomonas malvacearum. Pack: 20 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1189RE. |  |
| XMC-[d3] | XMC-[d3] is a deuterium labelled 3,5-Xylyl methylcarbamate, an acetylcholinesterase inhibitor used as an insecticide. Alternative Names: XMC-d3; 3,5-Xylyl methylcarbamate-d3; Cosban-d3; Maqbarl-d3; Macbal-d3. Molecular formula: C10H10D3NO2. Mole weight: 182.23. | |
| XMC (pesticide) | XMC (pesticide) is a pesticide used in pesticide formulation for the protection of green tea crops. Group: Biochemicals. Grades: Highly Purified. CAS No. 2655-14-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13NO2, Molecular Weight: 179.22. US Biological Life Sciences. | Worldwide |
| XMD16-5 | XMD16-5is a novel non-receptor tyrosine kinase TNK2 inhibitor (IC50 = 16 nM and 77 nM for D163E and R806Q mutant TNK2, respectively). Alternative Names: 2-[4-(4-hydroxypiperidin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one; XMD-16-5; XMD 16-5; XMD165; XMD-165; XMD 165. CAS No. 1345098-78-3. Molecular formula: C23H24N6O2. Mole weight: 416.48. | |
| XMD8-92 | XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with Kds of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with Kds of 190, 600 and 890 nM, respectively. Anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234480-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14443. | |
| XMT-1519 conjugate-1 | XMT-1519 conjugate-1 (compound 31) is part of the drug-linker conjugate for ADC and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2720500-19-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148067. | |
| XMT-1519 conjugate-1 | XMT-1519 conjugate-1 is a linker for the HER-2 monoclonal antibody XMT-1519. XMT-1519 can be used to synthesize ADC and increase anti-tumor activity. CAS No. 2720500-19-4. Molecular formula: C101H149N23O42. Mole weight: 2357.39. | |
| XMU-MP-1 | XMU-MP-1 is a reversible and selective MST1/2 inhibitor. It suppresses activities of MST1/2 kinase, then activating the downstream effector Yes-associated protein and promoting cell growth. Studies indicated that the pharmacological modulation of MST1/2 kinase activities offered a new way to potentiate tissue repair and regeneration, and XMU-MP-1 is the first lead for the development of targeted regenerative therapeutics. Uses: Targeted regenerative therapeutics. Alternative Names: 4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide; 4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide; Benzenesulfonamide, 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-. Grades: >98%. CAS No. 2061980-01-4. Molecular formula: C17H16N6O3S2. Mole weight: 416.48. | |
| XMU-MP-1 | XMU-MP-1 is an inhibitor of MST1/2 with IC50 values of 71.1±12.9 nM and 38.1±6.9 nM against MST1 and MST2, respectively. Group: Inhibitors. CAS No. 2061980-01-4. Pack Sizes: 2mg. Product ID: S8334. Formula: C17H16N6O3S2. Smiles: CN1C2=C(C(=O)N(C3=CN=C(N=C31)NC4=CC=C(C=C4)S(=O)(=O)N)C)SC=C2. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| XMU-MP-1 | XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2061980-01-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100526. | |
| XMU-MP-10 | XMU-MP-10 is a selective NEDD4 inhibitor with a KD of 43.92 nM. XMU-MP-10 selectively inhibits NEDD4 auto-ubiquitination without affecting other ubiquitination activity, upregulates of β-TrCP and results YAP degradation without affecting NEDD4 protein expression. XMU-MP-10 exhibits significant in vivo efficacy in inhibiting TNBC tumor growth by enhancing CD8+ T cell infiltration. XMU-MP-10 enhances antitumor immune responses through the β-TrCP/YAP/ECM axis. XMU-MP-10 can be used for Triple-Negative Breast Cancer (TNBC) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2251132-02-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-179570. | |
| XMU-MP-8 | XMU-MP-8 (SKPer1) is a potent molecular glue degrader that targets the oncoprotein SKP2. XMU-MP-8 simultaneously binds to the F-box domain of SKP2 (Kd ? 36 μM) and the N-terminal TPR domain of the E3 ligase STUB1 (Kd ? 2.5 μM), forming a stable SKP2-SKPer1-STUB1 ternary complex (Kd ? 8.9 nM) that induces SKP2 ubiquitination and proteasomal degradation. XMU-MP-8 selectively eliminates SKP2-expressing cancer cells. XMU-MP-8 exhibits substantial tumour suppression with good safety profiles in vivo. XMU-MP-8 can be used for cancer research, such as non-small cell lung adenocarcinoma (NSCLC) and prostatic adenocarcinoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKPer1. CAS No. 2271314-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W1128879. | |
| XMU-MP-9 | XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used for the study of colon, lung and pancreatic cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2251130-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162809. | |
| X-Neu5Ac sodium | X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: X-NeuNAc. CAS No. 160369-85-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-32264. | |
| X-NeuNAc | Used as a substrate for the detection of sialidase-like enzyme in screening of enzymes, studying physiological activities of gangliosides, and recombinant technologies. Alternative Names: N-Acetyl-2-O-(5-bromo-4-chloro-1H-indol-3-yl)-α-neuraminic Acid Monosodium Salt; 5-bromo-4-chloro-1H-indol-3-yl 5-(Acetylamino)-3,5-dideoxy-D-glycero-α-D-galacto-2-nonulopyranosidonic Acid Monosodium Salt; 5-Bromo-4-chloro-3-indolyl-α-D-N-acetylneuraminic acid sodium salt. Grades: ≥98.0%. CAS No. 160369-85-7. Molecular formula: C19H25N2NaO3S. Mole weight: 559.73. | |
| XO-379 | XO-379. | |
| XO44 | XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK2 and CDK1. XO44 also labels CDK4 proteins in cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-6808472. CAS No. 2088112-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122609. | |
| XPC-6444 | XPC-6444 is a highly potent, isoform-selective, and CNS-penetrant NaV1.6 inhibitor (IC50=41 nM for hNaV1.6). XPC-6444 also displays potent block of NaV1.2 (IC50=125 nM). XPC-6444 shows anticonvulsant activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230144-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128772. | |
| XPC-7724 | XPC-7724 is a selective Nav1.6 channel inhibitor with a IC50 value of 0.078 μM. XPC-7724 can be used in the study of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3121409-76-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157784. | |
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