A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Xipamide is a diuretic and antihypertensive agent. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide; Aquaphor; Chronexan; Diurex; Lumitens. Grades: Highly Purified. CAS No. 14293-44-8. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Xipamide-d6
A labeled diuretic and antihypertensive. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide-d6; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide-d6; Aquaphor-d6; Chronexan-d6; Diurex-d6; Lumitens-d6. Grades: Highly Purified. CAS No. 1330262-09-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Xipamide impurity 1
Xipamide impurity 1. Uses: For analytical and research use. CAS No. 14665-31-7. Molecular formula: C7H4Cl2O5S. Mole weight: 271.06. Catalog: APB14665317.
XIRAN Heatboosters
XIRAN Heatboosters.
Xirestomig
Xirestomig (ATG-101) is a tetravalent "2+2" PD-L1×4-1BB bispecific antibody. Xirestomig binds PD-L1 and 4-1BB concurrently, with a greater affinity for PD-L1, and potently activated 4-1BB+ T cells when cross-linked with PD-L1-positive cells. Xirestomig activates exhausted T cells upon PD-L1 binding. Xirestomig displays potent antitumor activity in numerous in vivo tumor models, including those resistant or refractory to immune checkpoint inhibitors (ICIs)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ATG-101. CAS No. 2756879-35-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990778.
XJ735
XJ735, a RGD peptidomimetic αVβ3 integrin antagonist, contains anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. Synonyms: XJ 735; XJ-735; Cyclo[L-alanyl-L-arginylglycyl-L-α-aspartyl-3-(aminomethyl)benzoyl]; 3,6,9,12,15-Pentaazabicyclo[15.3.1]heneicosa-1(21),17,19-triene-5-acetic acid, 11-[3-[(aminoiminomethyl)amino]propyl]-14-methyl-4,7,10,13,16-pentaoxo-, (5S,11S,14S)-. Grade: ≥95%. CAS No. 153381-95-4. Molecular formula: C23H32N8O7. Mole weight: 532.55.
XJB-5-131
XJB-5-131 is a mitochondria-targeted ROS and electron scavenger[1]. XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria[2]. XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs)[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 866404-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-129460.
XK-101-2
XK-101-2 is a nucleoside antibiotic isolated from Micromonospora chalcea subsp. It exhibits activity against Mycobacterium phlei and gram-positive bacteria. Molecular formula: C11H13N3O5. Mole weight: 267.24.
XK-90
XK-90 is produced by Streptomyces sp. It is active against Gram-positive and Gram-negative bacteria. Synonyms: Antibiotic XK 90; 5-(2-Acetylhydrazino)salicylaldehyde. CAS No. 61172-42-7. Molecular formula: C9H10N2O3. Mole weight: 194.19.
XL01126
XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)) composed of the VHL ligand VH 101, thiol (HY-47851, blue part) and the LRRK2 inhibitor HG-10-102-01 (HY-13488, red part). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3011029-58-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148030.
XL041
XL041 (BMS-852927) is an LXRβ-selective agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-852927. CAS No. 1256918-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101973.
XL177A
XL177A is a covalent USP7 inhibitor that blocks the deubiquitinase activity of USP7. XL177A destabilizes non-canonical PRC1 complexes or KDM6A and reduces chromatin deposition of H2AK119Ub, thereby relieving the repression of neuronal differentiation programs. Meanwhile, XL177A also regulates the ELOF1-UVSSA-USP7-nuclear β-catenin axis, decreasing the transcription levels of related proteins and the accumulation of nuclear β-catenin. XL177A exerts antiviral effects by reducing the expression levels of coronavirus receptors, and exhibits inhibitory activity against APC-mutated colorectal cancer cells, neuroblastoma, and coronaviruses including SARS-CoV-2 variants. XL177A is mainly used in studies related to colorectal cancer, neuroblastoma, and coronavirus infections[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417089-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138794.
XL 184
XL 184. Group: Biochemicals. Grades: Purified. CAS No. 849217-68-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XL228
XL228 is a multi-targeted tyrosine kinase inhibitor with IC50s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src and Lyn, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 898280-07-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15749.
XL-3158
XL-3158 is a selective and cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor (IC50: 11.1 μM for human cGAS, 2.19 μM for mouse cGAS). XL-3158 simultaneously occupy allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation and thereby attenuating the cGAS-DNA interactions. XL-3158 inhibits cGAS by targeting phase separation. XL-3158 efficiently penetrates cells by inhibiting aggregate formation, effectively reducing the local concentration of cGAS within cells. XL-3158 can be used for the study of cGAS-dependent inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3117797-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-174802.
XL388
XL388 is a highly potent and ATP-competitive mTOR inhibitor with an IC50 of 9.9 nM. XL388 simultaneously inhibits both mTORC1 and mTORC2. Uses: Scientific research. Category: Signaling pathways. CAS No. 1251156-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13806.
XL 388
XL 388. Group: Biochemicals. Grades: Purified. CAS No. 1251156-08-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XL413
XL413 is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-863233. CAS No. 1169558-38-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15260.
XL 413 hydrochloride
XL 413 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1169562-71-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XL413 monohydrochloride
XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-863233 monohydrochloride. CAS No. 2062200-97-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15260A.
XL-784
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1224964-36-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19485.
XL888
XL888 is a potent and orally active HSP90 inhibitor with an IC50 value of 24 nM. XL888 shows anti-proliferation activity and induces Apoptosis. XL888 shows anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1149705-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13313.
XM462
XM462 is a dihydroceramide desaturase inhibitor. XM462 produced a mixed-type inhibition (Ki=2 μM) in vitro. XM462 has dihydroceramide desaturase inhibition both in vitro and in cultured cells with IC50 values of 8.2 and 0.78 μM, respectively. XM462 can be used for the research of tumor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1045857-53-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-135818.
XmAb 5592
XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1221901-33-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99381.
Xma I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus -2 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme 95% of the dna fragments can be ligated. of these 90% can be recut. Group: Restriction Enzymes. Purity: 300U;1500U. C↑CCGGG GGGCC↓C. Activity: 3000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene XmaI from Xanthomonas malvacearum. Pack: 20 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1189RE.
XMC-[d3]
XMC-[d3] is a deuterium labelled 3,5-Xylyl methylcarbamate, an acetylcholinesterase inhibitor used as an insecticide. Synonyms: XMC-d3; 3,5-Xylyl methylcarbamate-d3; Cosban-d3; Maqbarl-d3; Macbal-d3. Molecular formula: C10H10D3NO2. Mole weight: 182.23.
XMC (pesticide)
XMC (pesticide) is a pesticide used in pesticide formulation for the protection of green tea crops. Group: Biochemicals. Grades: Highly Purified. CAS No. 2655-14-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H13NO2, Molecular Weight: 179.22. US Biological Life Sciences.
Worldwide
XMD8-92
XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with Kds of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with Kds of 190, 600 and 890 nM, respectively. Anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234480-50-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14443.
XMT-1519 conjugate-1
XMT-1519 conjugate-1 (compound 31) is part of the drug-linker conjugate for ADC and can be conjugated with the HER-2 monoclonal antibody Calotatug (XMT-1519) (HY-P990909) for the synthesis of ADC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2720500-19-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148067.
XMU-MP-1
XMU-MP-1 is an inhibitor of MST1/2 with IC50 values of 71.1±12.9 nM and 38.1±6.9 nM against MST1 and MST2, respectively. Group: Inhibitors. CAS No. 2061980-01-4. Pack Sizes: 2mg. Product ID: S8334. Formula: C17H16N6O3S2. Smiles: CN1C2=C(C(=O)N(C3=CN=C(N=C31)NC4=CC=C(C=C4)S(=O)(=O)N)C)SC=C2. Storage Conditions: 2 years -80 in solvent.
United States; Europe
XMU-MP-1
XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2061980-01-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100526.
XMU-MP-10
XMU-MP-10 is a selective NEDD4 inhibitor with a KD of 43.92 nM. XMU-MP-10 selectively inhibits NEDD4 auto-ubiquitination without affecting other ubiquitination activity, upregulates of β-TrCP and results YAP degradation without affecting NEDD4 protein expression. XMU-MP-10 exhibits significant in vivo efficacy in inhibiting TNBC tumor growth by enhancing CD8+ T cell infiltration. XMU-MP-10 enhances antitumor immune responses through the β-TrCP/YAP/ECM axis. XMU-MP-10 can be used for Triple-Negative Breast Cancer (TNBC) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2251132-02-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-179570.
XMU-MP-8
XMU-MP-8 (SKPer1) is a potent molecular glue degrader that targets the oncoprotein SKP2. XMU-MP-8 simultaneously binds to the F-box domain of SKP2 (Kd ? 36 μM) and the N-terminal TPR domain of the E3 ligase STUB1 (Kd ? 2.5 μM), forming a stable SKP2-SKPer1-STUB1 ternary complex (Kd ? 8.9 nM) that induces SKP2 ubiquitination and proteasomal degradation. XMU-MP-8 selectively eliminates SKP2-expressing cancer cells. XMU-MP-8 exhibits substantial tumour suppression with good safety profiles in vivo. XMU-MP-8 can be used for cancer research, such as non-small cell lung adenocarcinoma (NSCLC) and prostatic adenocarcinoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKPer1. CAS No. 2271314-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W1128879.
XMU-MP-9
XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used for the study of colon, lung and pancreatic cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2251130-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-162809.
X-Neu5Ac sodium
X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a Km of 0.89 mM for neuraminidase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: X-NeuNAc. CAS No. 160369-85-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-32264.
XO-379
XO-379.
XO44
XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK2 and CDK1. XO44 also labels CDK4 proteins in cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-6808472. CAS No. 2088112-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122609.
XPC-6444
XPC-6444 is a highly potent, isoform-selective, and CNS-penetrant NaV1.6 inhibitor (IC50=41 nM for hNaV1.6). XPC-6444 also displays potent block of NaV1.2 (IC50=125 nM). XPC-6444 shows anticonvulsant activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230144-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128772.
XPC-7724
XPC-7724 is a selective Nav1.6 channel inhibitor with a IC50 value of 0.078 μM. XPC-7724 can be used in the study of neurological diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3121409-76-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157784.
XPF-SE1
XPF-SE1 is an antibacterial peptide isolated from Silurana epitropicalis. It has strong activity against methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Gly-Leu-Phe-Leu-Asp-Thr-Leu-Lys-Lys-Phe-Ala-Lys-Ala-Gly-Met-Glu-Ala-Val-Ile-Asn-Pro-Lys. Grade: >95%. Molecular formula: C111H183N27O29S. Mole weight: 2391.91.
XPF-SE3
XPF-SE3 is an antibacterial peptide isolated from Silurana epitropicalis. It has strong activity against methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Gly-Phe-Trp-Thr-Thr-Ala-Ala-Glu-Gly-Leu-Lys-Lys-Phe-Ala-Lys-Ala-Gly-Leu-Ala-Ser-Ile-Leu-Asn-Pro-Lys. Grade: >95%. Molecular formula: C123H195N31O32. Mole weight: 2620.10.
XPF-SE4
XPF-SE4 is an antibacterial peptide isolated from Silurana epitropicalis. It has strong activity against methicillin-resistant Staphylococcus aureus (MRSA). Synonyms: Gly-Val-Trp-Thr-Thr-Ile-Leu-Gly-Gly-Leu-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Leu-Glu-Ala-Leu-Thr-Asn-Pro-Lys. Grade: >96%. Molecular formula: C121H199N31O32. Mole weight: 2600.11.
XPF-St4
XPF-St4 is an antibacterial peptide isolated from the African clawed frog Silurana tropicalis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Trp-Ala-Ser-Ser-Ile-Gly-Ser-Ile-Leu-Gly-Lys-Phe-Ala-Lys-Gly-Gly-Ala-Gln-Ala-Phe-Leu-Gln-Pro-Lys. Grade: >96%. Molecular formula: C117H183N31O31. Mole weight: 2519.94.
XPF-St5
XPF-St5 is an antibacterial peptide isolated from the African clawed frog Silurana tropicalis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Trp-Leu-Pro-Thr-Phe-Gly-Lys-Ile-Leu-Arg-Lys-Ala-Met-Gln-Leu-Gly-Pro-Lys-Leu-Ile-Gln-Pro-Ile. Grade: >96%. Molecular formula: C129H213N33O28S. Mole weight: 2706.39.
XPF-St6
XPF-St6 is an antibacterial peptide isolated from the African clawed frog Silurana tropicalis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Val-Trp-Ser-Thr-Ile-Leu-Gly-Gly-Leu-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Leu-Asp-Ala-Ile-Val-Asn-Pro-Lys. Grade: >95%. Molecular formula: C120H197N31O31. Mole weight: 2570.08.
XPF-St7
XPF-St7 is an antibacterial peptide isolated from the African clawed frog Silurana tropicalis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Leu-Leu-Ser-Asn-Val-Ala-Gly-Leu-Leu-Lys-Gln-Phe-Ala-Lys-Gly-Gly-Val-Asn-Ala-Val-Leu-Asn-Pro-Lys. Grade: >96%. Molecular formula: C114H194N32O31. Mole weight: 2509.00.
XPF-St8
XPF-St8 is an antibacterial peptide isolated from the African clawed frog Silurana tropicalis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Phe-Met-Ser-Lys-Val-Ala-Asn-Phe-Ala-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Val-Asn-Ala-Ile-Met-Asn-Gln-Lys. Grade: >97%. Molecular formula: C121H196N34O31S2. Mole weight: 2687.23.
XPhos
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl. CAS No. 564483-18-7. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0006.
X-press Tag Peptide
X-press Tag Peptide, an N-terminal leader peptide containing a polyhistidine sequence, is a tag peptide used for protein purification. Synonyms: H-Asp-Leu-Tyr-Asp-Asp-Asp-Asp-Lys-OH; L-alpha-aspartyl-L-leucyl-L-tyrosyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-lysine. Molecular formula: C41H59N9O20. Mole weight: 997.96.
XPW1
XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear cell renal cell carcinoma (ccRCC) and low toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2700286-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149673.
XR651
XR651 is a naphthacene-5,12-dione produced by Amycolatopsis X 16735. Synonyms: XR-651; XR 651. CAS No. 189697-45-8. Molecular formula: C21H16O5. Mole weight: 348.3.
XRD-0394
XRD-0394 is a potent and orally active dual ATM and DNA-PKcs inhibitor with IC50s of 0.39 nM and 0.89 nM, respectively. XRD-0394 shows selectivity over other PIKK and PI3K family members. XRD-0394 significantly enhances tumor cell killing in vitro and in vivo under therapeutic ionizing radiation conditions. XRD-0394 can potentiate the effects of PARP and topoisomerase I inhibitors in vitro[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2595308-10-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162472.
XRK3F2
XRK3F2 is a p62 (sequestosome-1) ZZ domain inhibitor that has specificity for the p62-ZZ domain over other p62 signaling domains. XRK3F2 blocks TNFα effects and upregulation in bone marrow stromal cells, and induces multiple myeloma cell apoptosis. XRK3F2 can be used for the research of multiple myeloma bone disease, acute myeloid leukemia, and multiple myeloma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375193-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112904.
XRP44X
XRP44X. Group: Biochemicals. Grades: Purified. CAS No. 729605-21-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XST-14
XST-14 is a potent, competitive and highly selective ULK1 inhibitor with an IC50 of 26.6 nM. XST-14 induces autophagy inhibition by reducing the phosphorylation of the ULK1 downstream substrate. XST-14 induces apoptosis in hepatocellular carcinoma (HCC) cells and has antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2607143-50-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-137506.
XT2
XT2 is a potent, orally active, and selective inhibitor of NF-κB-inducing kinase (NIK) with an IC50 of 9.1 nM. XT2 suppresses CCl4-induced upregulation of ALT, a key biomarker of acute liver injury. XT2 also decreases immune cell infiltration into the injured liver tissue. XT2 has the potential for the research of liver inflammatory diseases[1]. XT2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2582816-37-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145801.
XT-2
XT-2 is an antibacterial peptide isolated from Xenopus tropicalis (Diploid clawed frog, Africa). It has activity against gram-negative bacteria. Synonyms: Gly-Cys-Trp-Ser-Thr-Val-Leu-Gly-Gly-Leu-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Leu-Glu-Ala-Ile-Val-Asn-Pro-Lys. Grade: >95%. Molecular formula: C118H193N31O31S. Mole weight: 2574.08.
XT-4
Antimicrobial peptide 4 is an antimicrobial peptide found in Xenopus tropicalis skin secretions (Western clawed frog, Silurana tropicalis). It has antibacterial and antifungal activity. Synonyms: Antimicrobial peptide 4; Gly-Val-Phe-Leu-Asp-Ala-Leu-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Met-Asn-Ala-Val-Leu-Asn-Pro-Lys; Xenopus tropicalis antimicrobial peptide 4. Grade: ≥97%. CAS No. 398143-81-2. Molecular formula: C107H176N28O27S. Mole weight: 2318.81.
XT-5
Antimicrobial peptide 5 is an antimicrobial peptide found in Xenopus tropicalis skin secretions (Western clawed frog, Silurana tropicalis). It has antibacterial and antifungal activity. Synonyms: Antimicrobial peptide 5; PGLa-like peptide-SE1; PGLa-SE1; Gly-Met-Ala-Thr-Lys-Ala-Gly-Thr-Ala-Leu-Gly-Lys-Val-Ala-Lys-Ala-Val-Ile-Gly-Ala-Ala-Leu-NH2; Xenopus tropicalis antimicrobial peptide 5; glycyl-L-methionyl-L-alanyl-L-threonyl-L-lysyl-L-alanylglycyl-L-threonyl-L-alanyl-L-leucylglycyl-L-lysyl-L-valyl-L-alanyl-L-lysyl-L-alanyl-L-valyl-L-isoleucylglycyl-L-alanyl-L-alanyl-L-leucinamide. Grade: ≥96%. CAS No. 398143-82-3. Molecular formula: C88H160N26O24S. Mole weight: 1998.47.
XT-6
Antimicrobial peptide 6 is an antimicrobial peptide found in Xenopus tropicalis skin secretions (Western clawed frog, Silurana tropicalis). It has antibacterial and antifungal activity. Synonyms: Antimicrobial peptide 6; Gly-Phe-Leu-Gly-Ser-Leu-Leu-Lys-Thr-Gly-Leu-Lys-Val-Gly-Ser-Asn-Leu-Leu-NH2; Xenopus tropicalis antimicrobial peptide 6. Grade: 97%. CAS No. 398143-84-5. Molecular formula: C84H146N22O22. Mole weight: 1816.22.
XT-7
Antimicrobial peptide 7 is an antimicrobial peptide found in Xenopus tropicalis skin secretions (Western clawed frog, Silurana tropicalis). It has antibacterial and antifungal activity. Synonyms: Antimicrobial peptide 7; Gly-Leu-Leu-Gly-Pro-Leu-Leu-Lys-Ile-Ala-Ala-Lys-Val-Gly-Ser-Asn-Leu-Leu-NH2; glycyl-L-leucyl-L-leucyl-glycyl-L-prolyl-L-leucyl-L-leucyl-L-lysyl-L-isoleucyl-L-alanyl-L-alanyl-L-lysyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-leucyl-L-leucinamide; Xenopus tropicalis antimicrobial peptide 7. Grade: >96%. CAS No. 398143-86-7. Molecular formula: C83H150N22O20. Mole weight: 1776.25.
XTP/dITP diphosphatase
The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP and dITP. The activity is dependent on divalent cations, Mg2+ is preferred. Group: Enzymes. Synonyms: hypoxanthine/xanthine dNTP pyrophosphatase; rdgB (gene name). Enzyme Commission Number: EC 3.6.1.66. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4639; XTP/dITP diphosphatase; EC 3.6.1.66; hypoxanthine/xanthine dNTP pyrophosphatase; rdgB (gene name). Cat No: EXWM-4639.
XTT sodium
XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product. Uses: Scientific research. Category: Signaling pathways. CAS No. 111072-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122131.
XVA143
XVA143, an α/β I-like allosteric antagonist, inhibits LFA-1 dependent firm adhesion, while at the same time it enhances adhesion in shear flow and rolling both in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 264275-77-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139202.
XX-650-23
XX-650-23 is a potent CREB inhibitor. XX-650-23inhibits CREB function through disruption of CBP-CREB interaction. XX-650-23 can be used for AML research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 117739-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119769.
XY028-140
XY028-140 is a PROTAC connected by ligands for Cereblon and CDK. XY028-140 inhibits both CDK4/6 expression and CDK4/6 activity in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2229974-83-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138946.
XYD049
XYD049 is a CRBN-based molecular glue degrader targeting GSPT1, with a DC50 of 19 nM. XYD049 mediates the formation of a ternary complex between CRBN and GSPT1, thereby triggering CRBN- and proteasome-dependent degradation of GSPT1. By degrading GSPT1, XYD049 downregulates castration-resistant prostate cancer (CRPC)-related oncogenes, including BCL2, CDK2, E2F3, EGFR, HSP90B1, TMPRSS2, AR, AR-V7, PSA and c-Myc. XYD049 inhibits cancer cell growth and suppresses tumor growth in mice. XYD049 can be used for research on castration-resistant prostate cancer. XYD049 consists of a linker (black part) NH2-C5-NH-Boc (HY-W004710), a CRBN-based E3 ligase ligand (blue part) Thalidomide 4-fluoride (HY-41547), and a target protein ligand (red part) GSPT1 ligand-1 (HY-170821), among which the E3 ligase ligand plus linker forms the conjugate E3 Ligase Ligand-linker Conjugate 158 (HY-170822)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3006788-11-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-170820.
XYDAR
XYDAR.
Xylan
5g Pack Size. Group: Building Blocks, Organics. CAS No. 9014-63-5. Prepack ID 12207874-5g. See USA prepack pricing.
Xylan
Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9014-63-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-107846.