A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Zibotentan (ZD4054) is a potent, selective and orally active endothelin A (ET A ) receptor antagonist with a K i of 13 nM. Zibotentan has no inhibitory effect on ETB. Zibotentan has anticancer effects and can be used for castration-resistant prostate cancer (CRPC) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD4054. CAS No. 186497-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10088.
Ziconotide acetate
Ziconotide acetate (SNX-111 acetate), a peptide, is a potent and selective block of N-type calcium channels antagonist. Ziconotide acetate reduces synaptic transmission, and can be used for chronic pain research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: SNX-111 acetate. CAS No. 914454-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0062B.
Ziconotide acetate
Ziconotide acetate. Group: Biochemicals. Alternative Names: ω-Conotoxin M VIIA acetate; ω-Conopeptide MVIIA acetate; Prialt acetate. Grades: Highly Purified. CAS No. 914454-03-8. Pack Sizes: 1mg, 2mg. Molecular Formula: C104H176N36O34S7. US Biological Life Sciences.
Worldwide
Ziconotide Polyacetate
Α selective antagonist of N-type voltage sensitive calcium channels (VSCC). Blocks neurotransmitter release by preventing depolarization-induced calcium influx. Used as a ligand for binding studies of voltage sensitive calcium channels. Analgesic; neuroprotective. Group: Biochemicals. Alternative Names: ω-Conotoxin M VIIA Acetate; ω-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Zicronapine
Zicronapine, an inden derivative, has been found to be neurotransmitter receptor modulators of sorts of neurotransmitter and was studied against Schizophrenia. Synonyms: Zicronapine; Lu 31-130; Lu31-130; Lu-31-130; Lu 31130; Lu31130; Lu-31130; UNII-QZV11V7G6A; 4-[(1R,3S)-6-chloro-3-phenyl-2,3-dihydro-1H-inden-1-yl]-1,2,2-trimethylpiperazine. Grades: 98%. CAS No. 170381-16-5. Molecular formula: C22H27ClN2. Mole weight: 354.92.
Zidebactam
Zidebactam is a β-lactamase inhibitor which possesses intrinsic antibacterial activity. Zidebactam is undergoing clinical development for the treatment of carbapenem-resistant Gram-negative infections. Uses: Bacterial infections. Synonyms: WCK-5107; WCK 5107; WCK5107; Zidebactam; (1R,2S,5R)-7-oxo-2-(2-((R)-piperidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Grades: 98%. CAS No. 1436861-97-0. Molecular formula: C13H21N5O7S. Mole weight: 391.40.
Zidebactam
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor [1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC 50 of 0.26 μg/mL [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WCK-5107. CAS No. 1436861-97-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120859.
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Group: Inhibitors. Alternative Names: 3-AZIDO-3-DEOXYTHYMIDINE; 1-(4-azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1h-pyrimidine-2, 4-dione; 1-((2R, 4S, 5S)-4-AZIDO-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-5-METHYL-1H-PYRIMIDINE-2, 4-DIONE; AZT; AZIDOTHYMIDINE; ZIDOVUDINE; 3'-azido-3'-deoxy-thymidin; bwa509u. CAS No. 30516-87-1. Molecular formula: C10H13N5O5. Mole weight: 283.24. Purity: 0.9993. Catalog: ACM30516871.
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor ( NRTI ), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Azidothymidine; AZT; ZDV. CAS No. 30516-87-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17413.
Zidovudine Related Compound B
One of the impurities of Zidovudine, which is a reverse transcriptase inhibitor and could restrain the HIV-1 replication. Synonyms: 3'-Chloro-2',3'-dideoxy-5-methyluridine; ClddT; 3'-Chloro-3'-deoxythymidine; USP Zidovudine Related Compound B; 1-((2R,4S,5R)-4-Chloro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(3-Chloro-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 25526-94-7. Molecular formula: C10H13ClN2O4. Mole weight: 260.67.
Zidovudine USP Impurity G
One of the impurities of Zidovudine, which is a reverse transcriptase inhibitor and could restrain the HIV-1 replication. Synonyms: 3'-[3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxy-thymidine; Zidovudine Impurity G; AZT Dimer Impurity G. CAS No. 148665-49-0. Molecular formula: C20H25N7O8. Mole weight: 491.46.
Z-IETD-FMK
Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. Z-IETD-FMK inhibits T cell proliferation induced by PHA or anti-CD3 plus anti-CD28 without toxicity of resting T cells. Synonyms: caspase-8 inhibitor; Z-IE(OMe)TD(OMe)-FMK; Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F; Z-Ile-Glu(OMe)-Thr-Asp(OMe) fluoromethylketone; N-benzyloxycarbonyl-Ile-Glu(OMe)-Thr-Asp(OMe)-fluoromethylketone; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone. Grades: ≥95%. CAS No. 210344-98-2. Molecular formula: C30H43FN4O11. Mole weight: 654.69.
Zifanocyclinum is a tetracycline antibiotic. Synonyms: 2-Naphthacenecarboxamide, 9-(3-azabicyclo[3.1.0]hex-3-ylmethyl)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-. Grades: >98%. CAS No. 1420294-56-9. Molecular formula: C29H36N4O7. Mole weight: 552.62.
Ziftomenib
Ziftomenibum is an antineoplastic. Synonyms: KO539; KO-539; ziftomenibum. Grades: >98%. CAS No. 2134675-36-6. Molecular formula: C33H42F3N9O2S2. Mole weight: 717.87.
Ziftomenib
Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities (WO2017161028A1, compound 151) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KO-539. CAS No. 2134675-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132001.
Zigakibart
Zigakibart (BION-1301) is an IgG4-kappa, anti- TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256) humanized monoclonal antibody. Zigakibart shows anti-inflammatory activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BION-1301. CAS No. 2642175-46-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990070.
Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone
Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone is a cell permeable inhibitor of caspase-8 and granzyme B. The bis-methyl ester of Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone blocks CD95-induced apoptosis. Synonyms: Z-IETD-FMK; Z-IE(OMe)TD(OMe)-FMK; Methyl (5S,8S,11S)-5-[(2S)-2-butanyl]-14-(fluoroacetyl)-11-[(1R)-1-hydroxyethyl]-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate. Grades: ≥95%. CAS No. 1926163-59-8. Molecular formula: C30H43FN4O11. Mole weight: 654.69.
Z-Ile-Glu(O-t-butyl)-Ala-Leucinal
PSI is a drug that blocks the action of proteasomes, protein complexes that degrade unneeded and damaged proteins. It causes dopaminergic cell death in vitro and prevents activation of NF-κB in response to TNF-α and okadaic acid by inhibiting IκB-α degradation. Uses: Cysteine proteinase inhibitors. Synonyms: Proteasome Inhibitor I; PSI peptide; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-alpha-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester. Grades: ≥ 90 % by HPLC. CAS No. 158442-41-2. Molecular formula: C32H50N4O8. Mole weight: 618.76.
Z-Ile-Leu-aldehyde
Z-Ile-Leu-aldehyde ia a cell-permeable and reversible inhibitor that inhibits γ-secretase and Notch signaling. It induces apoptosis of murine MOPC315.BM myeloma cells with high Notch activity in vitro. It has potent anti-MM activity and reduces osteolytic lesions in vivo. Uses: Gamma secretase inhibitors and modulators. Synonyms: Z-IL-CHO; GSI-XII; Z-Ile-Leu-al; Z Ile Leu al; Z IL CHO; Gamma-secretase inhibitor XII; [(1S,2S)-1-((S)-1-Formyl-3-methyl-butylcarbamoyl)-2-methyl-butyl]-carbamic acid benzyl ester; Benzyl ((2S,3S)-3-methyl-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate; N-benzyloxycarbonyl-L-isoleucyl-L-leucinal. Grades: ≥95%. CAS No. 161710-10-7. Molecular formula: C20H30N2O4. Mole weight: 362.46.
Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Group: Inhibitors. Alternative Names: (±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea. CAS No. 111406-87-2. Molecular formula: C11H12N2O2S. Mole weight: 236.29. Appearance: A Crystalline Solid. Purity: 0.99. Catalog: ACM111406872.
Zileuton
Zileuton. Group: Biochemicals. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zileuton
Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077; Abbott 64077. CAS No. 111406-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14164.
Zileuton β-D-Glucuronide
A metabolite of Zileuton. Group: Biochemicals. Alternative Names: 1-O-[(Aminocarbonyl)(1-benzo[b]thien-2-ylethyl)amino]- β-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 141056-63-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Zileuton-d4
Zileuton-d4 is the deuterium labeled Zileuton. Zileuton (A 64077) is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties. Group: Inhibitors. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4; A-64077-d4; Abbott 64077-d4; Leutrol-d4; Zyflo-d4. CAS No. 1189878-76-9. Molecular formula: C11H8D4N2O2S. Mole weight: 240.31. Appearance: White Solid. Purity: 0.96. IUPACName: 1-[1-(1-benzothiophen-2-yl)-1,2,2,2-tetradeuterioethyl]-1-hydroxyurea. Canonical SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O. Catalog: ACM1189878769.
Zileuton-d4 (major)
An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea-d4;A-64077-d4; Abbott 64077-d4; Leutrol-d4; Zyflo-d4. Grades: Highly Purified. CAS No. 1189878-76-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zileuton Glucuronide
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Molecular formula: C17H20N2O8S. Mole weight: 412.42.
Zileuton Impurity 1
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: 1-(Benzo[b]thien-2-yl)ethanol; 2-(1-Hydroxyethyl)benzothiophene; 2-(1-Hydroxyethyl)thianaphthene; α-Methyl-2-benzo[b]thiophenemethanol; α-Methylbenzo[b]thiophene-2-methanol. CAS No. 51868-95-2. Molecular formula: C10H10OS. Mole weight: 178.25.
Zileuton Impurity 2
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxy O-phenyl Carbamate; Phenyl (1-(Benzo[b]thiophen-2-yl)ethyl)(hydroxy)carbamate. CAS No. 1026256-93-8. Molecular formula: C17H15NO3S. Mole weight: 313.38.
An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-(1-Benzo[b]thien-2-yl-ethyl)-N-hydroxyurea;A-64077; Abbott 64077; Leutrol; Zyflo. Grades: Highly Purified. CAS No. 111406-87-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zileuton Related Compound A
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-Dehydroxyzileuton; N-(1-Benzo[b]thien-2-ylethyl)urea; (1-Benzo[b]thien-2-ylethyl)urea; A 66193; Abbott 66193. CAS No. 171370-49-3. Molecular formula: C11H12N2OS. Mole weight: 220.29.
Zileuton sodium
Zileuton sodium is an inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes(LTB4, LTC4, LTD4 and LTE4) formation with an IC50 value of 0.5μM. Zileuton sodium has been reported to concentration-dependently inhibit the 5-lipoxygenase activity with an IC50 value of 0.5μM in RBL-1cell lysate. In addition, Zileuton sodium has been found to be a potent inhibitor of LTB formation with an IC50 value of 0.6μM. Furthermore, stimulated with A23187, Zileuton sodium has shown a dose-dependent reduction in LTB4 and 5-HETE generation in rat leukocyte with IC50 values of 0.38μM and 0.31μM, respectively. About 40-fold higher concentrations of Zileuton sodium also reduced the production of PGE2 with a IC50 of 16μM. Synonyms: Zyflo sodium. Grades: >98%. CAS No. 118569-21-4. Molecular formula: C11H11N2NaO2S. Mole weight: 258.27.
Zileuton sodium
Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase , exhibiting inflammatory activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 64077 sodium; Abbott 64077 sodium. CAS No. 118569-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14164A.
A metabolite of Zileuton. Group: Biochemicals. Alternative Names: N-Hydroxy-N-[1-(1-oxidobenzo[b]thien-2-yl)ethyl]urea. Grades: Highly Purified. CAS No. 1147524-83-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Zileuton Sulfoxide
One of the impurities of Zileuton, which is a 5-lipoxygenase inhibitor and could be used as an antiasthmatic agent. Synonyms: N-Hydroxy-N-[1-(1-oxidobenzo[b]thien-2-yl)ethyl]urea. CAS No. 1147524-83-1. Molecular formula: C11H12N2O3S. Mole weight: 252.29.
Zilovertamab
Zilovertamab (UC-961) is a humanised monoclonal antibody against ROR1 that blocks Wnt5a-induced ROR1 signalling [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: UC-961; Cirmtuzumab. CAS No. 2485779-13-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99201.
Zilovertamab
Zilovertamab is a first-in-class humanized monoclonal antibody that binds to ROR1. Zilovertamab has been undergoing clinical trials in combination with ibrutinib for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). Synonyms: cirmtuzumab; UC-961. CAS No. 2485779-13-1.
Zilpaterol
Zilpaterol. Group: Biochemicals. Alternative Names: (+/-) -trans-4, 5, 6, 7-Tetrahydro-7-hydroxy-6- (isopropylamino) imidazo[4, 5, 1-jk][1]benzazepin-2 (1H) -one; RU-42173. Grades: Highly Purified. CAS No. 119520-05-7. Pack Sizes: 1mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C14H19N3O2. US Biological Life Sciences.
Worldwide
Zilpaterol-13C3
Zilpaterol-13C3 is labelled Zilpaterol (Z430000), a β-Adrenergic agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C1113C3H19N3O2, Molecular Weight: 264.3. US Biological Life Sciences.
Worldwide
Zilpaterol-d7
Zilpaterol-d7. Uses: For analytical and research use. Group: Chiral molecules. CAS No. 1217818-36-4. IUPAC Name: (9S,10S)-10-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)-9-hydroxy-1,3-diazatricyclo[6.4.1.04,13]trideca-4,6,8(13)-trien-2-one. Molecular Formula: C14H12D7N3O2. Mole Weight: 268.36. Catalog: APS1217818364. Format: Neat.
Zilpaterol-d7
β-Adrenergic agonist. Growth promotant. Group: Biochemicals. Alternative Names: (+/-)-trans-4,5,6,7-Tetrahydro-7-hydroxy-6-(isopropylamino-d7)imidazo[4,5,1-jk][1]benzazepin-2(1H)-one; RU-42173-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zilpaterol hydrochloride
Zilpaterol hydrochloride. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites. Alternative Names: Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, monohydrochloride, (6R,7R)-rel- (9CI), Zilmax, Imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, 4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-, monohydrochloride, trans-, trans-(±)-Zilpaterol hydrochloride, Zilpaterol hydrochloride. CAS No. 119520-06-8. Molecular Formula: C14H19N3O2.HCl. Mole Weight: 297.78. Catalog: APS119520068. SMILES: Cl. CC (C)N[C@@H]1CCN2C (=O)Nc3cccc ([C@H]1O)c23. Format: Neat. Shipping: +20°C.
b-Adrenergic agonist. Growth promotant. Group: Biochemicals. Alternative Names: (±) -trans-4, 5, 6, 7-Tetrahydro-7-hydroxy-6- (isopropylamino) imidazo[4, 5, 1-jk][1]benzazepin-2 (1H) -one; RU-42173. Grades: Highly Purified. CAS No. 119520-05-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Ziltivekimab
Ziltivekimab (COR-001) is a humanized monoclonal antibody against IL-6 that effectively reduces serum CRP levels. Ziltivekimab possesses anti-inflammatory activity and can be used in research related to chronic systemic inflammation associated with chronic kidney disease (CKD) and cardiovascular diseases such as atherosclerosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: COR-001. CAS No. 2226654-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99505.
Zilucoplan
Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent complement component 5 (C5) inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: RA101495; RA3193. CAS No. 1841136-73-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3502.
Zilurgisertib
Zilurgisertib (INCB-000928; NBU-928) is a selective ALK 2 inhibitor for researching diseases such as cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB-000928; NBU-928. CAS No. 2173389-57-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145608.
ZIM
ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301298-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152246.
Zimberelimab
Zimberelimab (GLS-010) is a fully human IgG4 anti- PD-1 monoclonal antibody with an EC 50 of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC 50 values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical Hodgkins lymphoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GLS-010; AB-122; WBP-3055. CAS No. 2259860-24-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99109.
Zimeldine
Zimeldine. Group: Biochemicals. Alternative Names: (Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine; Zimelidine. Grades: Highly Purified. CAS No. 56775-88-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H17BrN2. US Biological Life Sciences.
Serotonin uptake inhibitor. Antidepressant. Group: Biochemicals. Alternative Names: (Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine; Zimelidine. Grades: Highly Purified. CAS No. 56775-88-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Zimelidine dihydrochloride
Zimelidine dihydrochloride is a 5-HT reuptake inhibitor with selectivity over noradrenalin and dopamine uptake (IC50 = 0.33, 8.2 and 12 μM, respectively). Zimelidine modulates nociception and induces hyperglycemia in vivo, and is used as an orally active antidepressant. Synonyms: (2Z)-3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyrindinyl)-2-propen-1-amine dihydrochloride; Zimeldine hydrochloride; 2-Propen-1-amine, 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-, hydrochloride (1:2), (2Z)-; 2-Propen-1-amine, 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-, dihydrochloride, (2Z)-; 2-Propen-1-amine, 3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-, dihydrochloride, (Z)-; H 102/09 hydrochloride. Grades: ≥98% by HPLC. CAS No. 60525-15-7. Molecular formula: C16H17BrN2.2HCl. Mole weight: 390.15.
Zimelidine dihydrochloride
Zimelidine dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 60525-15-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Zimelidine dihydrochloride
Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine dihydrochloride is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60525-15-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110023.
Zinc
Zinc is a naturally occurring metal element used in the preparation of galvanized alloys such as steel for its contribution towards anti-corrosive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 7440-66-6. Pack Sizes: 25g, 50g. Molecular Formula: Zn, Molecular Weight: 65.38. US Biological Life Sciences.
Worldwide
ZINC00881524
ZINC00881524 is a specific ROCK inhibitor. Synonyms: ZINC00881524; ZINC-00881524; ZINC 00881524. N-(4,5-dihydrobenzo[e][1,3]benzothiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide. Grades: >98%. CAS No. 557782-81-7. Molecular formula: C21H20N2O3S. Mole weight: 380.46.
ZINC12613047 is a selective butyrylcholinesterase (BChE) inhibitor with IC50 value of 21 nM and 102.1 μM for human and mouse BChE, respectively. Synonyms: N-[[1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl]methyl]-N-(2-methoxyethyl)naphthalene-2-carboxamide. Grades: ≥95%. CAS No. 1069521-64-7. Molecular formula: C29H34N2O2. Mole weight: 442.6.