A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis. Z-LEHD-FMK exhibits the neuroprotective effect in a rat model of spinal cord trauma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 210345-04-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1010.
Z-LEHD-FMK TFA
Z-LEHD-FMK TFA (Caspase-9 Inhibitor) is a cell-permeable, competitive and irreversible inhibitor of enzyme caspase-9, which helps in cell survival. Group: Inhibitors. Alternative Names: Caspase-9 Inhibitor. CAS No. 524746-03-0. Pack Sizes: 2mg. Product ID: S7313. Formula: C34H44F4N6O12. Smiles: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2.C(=O)(C(F)(F)F)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
z-Leu-arg-7-amino-4-methylcoumarin
z-Leu-arg-7-amino-4-methylcoumarin. Alternative Names: Z-LEU-ARG-7-AMINO-4-METHYLCOUMARIN;Z-LEU-ARG-AMC;Z-LEU-ARG-AMC HYDROCHLORIDE. CAS No. 156192-32-4. Product ID: ACM156192324. Molecular formula: C30H38N6O6. Mole weight: 578.66. Alfa Chemistry - ISO 9001:32057 Certified.
Z-Leu-Arg-7-Amino-4-Methylcoumarin
Z-Leu-Arg-7-Amino-4-Methylcoumarin is a fluorescent substrate for cathepsin L, S, and V, human tissue kallikrein and the falcipains I-III. It is the preferred substrate for falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design. It is used to detect cathepsin K, an enzyme involved in osteoclast bone resorption. Synonyms: Z-LR-AMC; Cbz-Leu-Arg-AMC; Cathepsin K Substrate (fluorogenic); benzyloxycarbonyl-Leu-Arg-7-amino-4-methyl-coumarin; benzyl (S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate; L-Argininamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Benzyloxycarbonyl-L-leucyl-L-arginine 4-methylcoumaryl-7-amide. Grade: 99%. CAS No. 156192-32-4. Molecular formula: C30H38N6O6. Mole weight: 578.66.
Z-Leu-Arg-AMC
Z-Leu-Arg-AMC is a fluorogenic peptide substrate for cysteine proteases (e.g., Cathepsin) (Ex=350 nm, Em=460 nm). Z-Leu-Arg-AMC is preferentially cleaved by Cathepsin K and S under weakly acidic conditions, while its hydrolysis relies on residual Cathepsin S activity at neutral pH. Z-Leu-Arg-AMC serves as a substrate for recombinant Sphenophorus levis Cathepsin L, falcipain-2, falcipain-3, berghepain-2, knowlepain-2, vivapain-2, as well as falcipain-2 chimeras and constructs. It enables quantitative detection of cysteine protease activity in human inflammatory bronchoalveolar lavage fluid via fluorescence generation. Z-Leu-Arg-AMC can be used in research related to pulmonary inflammatory diseases and malaria[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 156192-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-142021.
Z-Leu-Arg-Gly-Gly-AMC
Z-Leu-Arg-Gly-Gly-AMC is a fluorescent substrate based on the C-terminal isopeptidase T (IPaseT) of ubiquitin and other ubiquitin C-terminal hydrolases (UCH). Synonyms: Z-LRGG-AMC.TFA; UCH Substrate. Grade: >95%. CAS No. 167698-68-2. Molecular formula: C36H45F3N8O10. Mole weight: 692.77.
Z-Leucine methyl ester
Z-Leucine methyl ester. Group: Biochemicals. Alternative Names: Z-L-Leu-OMe; (S)-Z-2-amino-4-methyl-pentanoic acid methyl ester. Grades: Highly Purified. CAS No. 51021-87-5. Pack Sizes: 10g, 25g, 50g, 100g. US Biological Life Sciences.
Z-Leu-Leu-Glu-AMC (Z-LLE-AMC) is a peptide-AMC linked substrate used to measure the postacidic-like hydrolysing activity of proteasome. Z-Leu-Leu-Glu-AMC can be used for the research of parkinson's disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-LLE-AMC. CAS No. 348086-66-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123053.
Z-Leu-Leu-OH
Z-Leu-Leu-OH. Synonyms: Z-L-leucyl-L-leucine; N-Carbobenzoxy-L-leucyl-L-leucine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-4-Methylpentanamido)-4-Methylpentanoic Acid; Z Leu Leu OH. Grade: ≥ 95% (HPLC). CAS No. 7801-71-0. Molecular formula: C20H30N2O5. Mole weight: 378.47.
Z-Leu-Leu-OH
Z-Leu-Leu-OH. Group: Biochemicals. Alternative Names: Z-L-leucyl-L-leucine; N-Carbobenzoxy-L-leucyl-L-leucine. Grades: Highly Purified. CAS No. 7801-71-0. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Z-Leu-Leu-OH ≥95% (HPLC)
Z-Leu-Leu-OH ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 7801-71-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Z-Leu-Leu-Tyr-α-keto aldehyde
Z-Leu-Leu-Tyr-α-keto aldehyde, an excellent inhibitor of serine and cysteine proteases, is an excellent inhibitor of chymotryptic-like activity of the proteasome with a Ki of about 3.0 nM. It may be valuable in identifying the role of the proteasome in the normal and abnormal pathways of protein catabolism in cells. Synonyms: L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-[(4-hydroxyphenyl)methyl]-2,3-dioxopropyl]-; Z-LLY-α-keto aldehyde; N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-(4-hydroxyphenyl)-3,4-dioxo-2-butanyl]-L-leucinamide; benzyl ((S)-1-(((S)-1-(((S)-1-(4-hydroxyphenyl)-3,4-dioxobutan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate; Cbz-Leu-Leu-Tyr-α-keto aldehyde. Grade: ≥95%. CAS No. 204649-66-1. Molecular formula: C30H39N3O7. Mole weight: 553.66.
Z-Leu-Phe-OH
Substrate for carboxypeptidase Y from baker's yeast. Synonyms: Z-L-leucyl-L-phenylalanine; (S)-2-((S)-2-(benzyloxycarbonylamino)-4-methylpentanamido)-3-phenylpropanoic acid; Z Leu Phe OH. Grade: ≥ 99% (HPLC). CAS No. 6401-63-4. Molecular formula: C23H28N2O5. Mole weight: 412.49.
Z-Leu-Phe-OH
Z-Leu-Phe-OH. Group: Biochemicals. Alternative Names: Z-L-leucyl-L-phenylalanine. Grades: Highly Purified. CAS No. 6401-63-4. Pack Sizes: 2g, 5g. US Biological Life Sciences.
Worldwide
Z-Leu-Phe-OH 99+% (TLC)
Z-Leu-Phe-OH 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Z-Leu-Trp-OH
Z-Leu-Trp-OH. Group: Biochemicals. Alternative Names: Z-L-leucyl-L-tryptophan. Grades: Highly Purified. CAS No. 53262-00-3. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
Z-Leu-Trp-OH
Z-Leu-Trp-OH. Synonyms: Z-L-leucyl-L-tryptophan; (S)-2-((S)-2-(benzyloxycarbonylamino)-4-methylpentanamido)-3-(1H-indol-3-yl)propanoic acid; Z Leu Trp OH. Grade: ≥ 99% (TLC). CAS No. 53262-00-3. Molecular formula: C25H29N3O5. Mole weight: 451.52.
Z-Leu-Trp-OH 99+%
Z-Leu-Trp-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Worldwide
Z-Leu-Tyr-chloromethylketone
Z-Leu-Tyr-chloromethylketone is an E.coli ClpP inhibitor. Synonyms: Carbobenzyloxyleucyl-tyrosine chloromethyl ketone; Z-LY-CMK; 2-{[(Benzyloxy)(hydroxy)methylidene]amino}-N-[4-chloro-1-(4-hydroxyphenyl)-3-oxobutan-2-yl]-4-methylpentanimidic acid. CAS No. 56979-35-2. Molecular formula: C24H29ClN2O5. Mole weight: 460.95.
z-Leu-val-gly-diazomethylketone
z-Leu-val-gly-diazomethylketone. Alternative Names: Z-LEU-VAL-GLY-DIAZOMETHYLKETONE;cbz-leu-val-gly diazomethyl ketone;N-benzyloxycarbonyl-leucyl-valyl-glycine diazomethane. CAS No. 119670-30-3. Product ID: ACM119670303. Molecular formula: C22H31N5O5. Mole weight: 445.51. Alfa Chemistry - ISO 9001:32057 Certified.
Z-LEVD-FMK
Z-LEVD-FMK is a cell-permeant and irreversible caspase-4 inhibitor. Synonyms: Z-LE(OMe)VD(OMe)-FMK; Z-Leu-Glu(OMe)-Val-Asp(OMe)-Fluoromethylketone; Cbz-Leu-Glu(OMe)-Val-Asp(OMe)-CH2F; Caspase 4 inhibitor. Grade: ≥95%. CAS No. 1135688-25-3. Molecular formula: C31H45FN4O10. Mole weight: 652.72.
Z-LEVD-FMK
Z-LEVD-FMK is a cell-permeable caspase-4 inhibitor. Z-LEVD-FMK blocks ER stress-induced apoptosis in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135688-25-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128707.