A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7619-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1617A.
Zuclopenthixol
The cis(Z)-form of Clopenthixol. Thioxanthene neuroleptic. Antipsychotic. Group: Biochemicals. Alternative Names: 4-[(3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Zuclopenthixol
Zuclopenthixol ((Z)-Clopenthixol) is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Z)-Clopenthixol. CAS No. 53772-83-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0163.
Zuclopenthixol (-)-10-Camphorsulfonic Acid Salt
The labeled cis(Z)-form of Clopenthixol. Thioxanthene neuroleptic. Antipsychotic. Group: Biochemicals. Alternative Names: 4-[(3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-d Salt. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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Zuclopenthixol-d4 (-)-10-Camphorsulfonic Acid Salt
The labeled cis(Z)-form of Clopenthixol. Thioxanthene neuroleptic. Antipsychotic. Group: Biochemicals. Alternative Names: 4-[(3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Zuclopenthixol-d4 Succinate Salt
The labeled cis(Z)-form of Clopenthixol. Thioxanthene neuroleptic. Antipsychotic. Group: Biochemicals. Alternative Names: 4-[(3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Zunsemetinib
Zunsemetinib (CDD-450) is an orally active and selective p38? mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATI-450; CDD-450. CAS No. 1640282-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-139553.
Z-VAD
Z-VAD is a competitive, irreversible pan- caspase inhibitor. Z-VAD inhibits all 10 caspases, except for caspase-2 which is only weakly inhibited. Z-VAD decreases radiation-induced apoptosis. Z-VAD induces both autophagy and necrosis in irradiated MDA-MB-231 and H460 mouse xenografts. Z-VAD with radiation produces a significant tumor growth delay and shows dramatic antiangiogenic effect in cancer xenograft [1]. Uses: Scientific research. Group: Peptides. CAS No. 162852-62-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164388.
Z-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor, which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-VAD(OH)-FMK. CAS No. 161401-82-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16658B.
Z-VAD-FMK
Z-VAD-FMK is a broad spectrum pan-caspase inhibitor that inhibits the intracellular activation of caspase-like proteases. Synonyms: Z-VAD (OMe)-FMK; Caspase Inhibitor I. Grade: >98.0%. CAS No. 187389-52-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49.
Cell-permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3-induced cells. Used in apoptosis and inflammasome studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 187389-52-2, 634911-81-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H30FN3O7. US Biological Life Sciences.
Worldwide
Z-VAD(OH)-FMK
Z-VAD(OH)-FMK, also known as Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone, is an irreversible tripeptide inhibitor of all caspases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-VAD(OH)-FMK; Z-Val-Ala-Asp-(OH)-Fluoromethyl Ketone. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 161401-82-7. Molecular formula: C21H28FN3O7. Mole weight: 453.47. Purity: >98%. IUPACName: (5S,8S,11S)-11-(2-fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oic acid. Canonical SMILES: O=C(O)C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O. Product ID: ACM161401827. Alfa Chemistry ISO 9001:2015 Certified.
Z-VAD(OMe)-FMK
Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor[1]. Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Val-Ala-Asp(OMe)-FMK. CAS No. 187389-52-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16658.
Z-Val-Ala-Asn-AMC is a substrate for the determination of cysteine endopeptidase required for antigen processing and has been used as a fluorescent substrate for porcine asparaginyl endopeptidase (AEP, legumain). Synonyms: Cbz-Val-Ala-Asn-AMC; L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Z-VAN-AMC; Butanediimidic acid, 2-[[(2S)-1-hydroxy-2-[[(2S)-1-hydroxy-2-[[hydroxy(phenylmethoxy)methylene]amino]-3-methylbutylidene]amino]propylidene]amino]-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2S)-; benzyl ((S)-1-(((S)-1-(((S)-4-amino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1,4-dioxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate. Grade: ≥95%. CAS No. 245036-58-2. Molecular formula: C30H35N5O8. Mole weight: 593.64.
Z-VAD-FMK is an irreversible tripeptide inhibitor of all caspases, useful in studies involving enzymes. Synonyms: Z-vad-FMK; N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide; benzyloxycarbonyl-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone. CAS No. 634911-81-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49.
Z-Val-Ala-OH
Z-Val-Ala-OH. Group: Biochemicals. Alternative Names: Z-L-valyl-L-alanine. Grades: Highly Purified. CAS No. 24787-89-1. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
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Z-Val-Ala-OH
Z-Val-Ala-OH is a useful reagent in the preparation and biological evaluation of peptide amide conjugates of nucleosides as prodrugs that are converted to parent drugs by action of DPPIV/CD26. Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme. Synonyms: Z-L-valyl-L-alanine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-3-Methylbutanamido)Propanoic Acid; Z Val Ala OH. Grade: ≥ 98% (HPLC). CAS No. 24787-89-1. Molecular formula: C16H22N2O5. Mole weight: 322.36.
Z-Val-Ala-OH 98+% (HPLC)
Z-Val-Ala-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Z-Val-Arg-Pro-DL-Arg-fluoromethylketone
Z-Val-Arg-Pro-DL-Arg-fluoromethylketone, a cell-permeable and irreversible inhibitor of para-caspase MALT1, is based on the sequence of a published optimal tetrapeptide substrate for the A. thaliana metacaspase AtMC9. Synonyms: MALT1 Inhibitor; Z-VRPR-FMK; L-Prolinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-(2-fluoroacetyl)butyl]-; Cbz-Val-Arg-Pro-DL-Arg-CH2F; N-[(Phenylmethoxy)carbonyl]-L-valyl-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-(2-fluoroacetyl)butyl]-L-prolinamide. Grade: ≥95%. CAS No. 1926163-57-6. Molecular formula: C31H49FN10O6. Mole weight: 676.79.
Z-Val-Asp(OMe)-Val-Ala-DL-Asp(OMe)-fluoromethylketone is a cell-permeable fluoromethylketone that specifically inhibits caspase-2 and, to a lesser extent, caspase-3 and caspase-7. Synonyms: Z-VD(OMe)VAD(OMe)-FMK; Z-VDVA-(DL-Asp)-FMK; Methyl (5S,8S,11S,14S)-17-(fluoroacetyl)-5,11-diisopropyl-8-(2-methoxy-2-oxoethyl)-14-methyl-3,6,9,12,15-pentaoxo-1-phenyl-2-oxa-4,7,10,13,16-pentaazanonadecan-19-oate. Grade: ≥90%. CAS No. 1926163-61-2. Molecular formula: C32H46FN5O11. Mole weight: 695.73.
z-Val-asp-val-ala-asp-afc
z-Val-asp-val-ala-asp-afc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CASPASE-2 SUBSTRATE I, FLUOROGENIC;Z-VDVAD-AFC;Z-VAL-ASP-VAL-ALA-ASP-AFC;Z-Val-Asp-Ala-Asp-AFC. Product Category: Heterocyclic Organic Compound. CAS No. 219138-08-6. Molecular formula: C39H45F3N6O13. Mole weight: 862.8. Product ID: ACM219138086. Alfa Chemistry ISO 9001:2015 Certified.
Z-Val-Asp-Val-Ala-Asp-AFC
Z-VDVAD-AFC is a fluorogenic substrate for caspase-2 (ICH-1). Synonyms: N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine; L-α-Asparagine, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-aspartyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-; Z-VDVAD-AFC. Grade: ≥95%. CAS No. 219138-08-6. Molecular formula: C39H45F3N6O13. Mole weight: 862.81.
z-Val-dl-asp-fluoromethylketone
z-Val-dl-asp-fluoromethylketone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBL23453, Z-VAL-DL-ASP -FLUOROMETHYLKETONE, 582317-87-1. Product Category: Heterocyclic Organic Compound. CAS No. 582317-87-1. Molecular formula: C19H25FN2O6. Mole weight: 396.410003 [g/mol]. Purity: 0.96. IUPACName: methyl 5-fluoro-3-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-4-oxopentanoate. Product ID: ACM582317871. Alfa Chemistry ISO 9001:2015 Certified. Categories: 582316-00-5.
z-Val-glu-ile-asp-afc
z-Val-glu-ile-asp-afc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MCA-VDQVDGWK(DNP)-NH2;MCA-VQVDGW-K(DNP)-NH2;MCA-VAL-ASP-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;MCA-VAL-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;CASPASE-6 SUBSTRATE III, FLUOROGENIC;CASPASE 6 (MCH2) SUBSTRATE 2, FLUOROGENIC;CASPASE-6, SUBSTRATE, FLUOROGENIC;CASPASE-7 S. Product Category: Heterocyclic Organic Compound. CAS No. 219138-06-4. Molecular formula: C38H44F3N5O12. Mole weight: 819.78. Product ID: ACM219138064. Alfa Chemistry ISO 9001:2015 Certified.
Z-Val-Glu-Ile-Asp-AFC
Z-Val-Glu-Ile-Asp-AFC is a fluorogenic substrate for caspase-6 (Mch2). Synonyms: Z-VEID-AFC; N-Acetyl-Val-Glu-Ile-Asp-7-amino-4-(trifluoromethyl)coumarin; N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-glutamyl-L-isoleucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine. Grade: 95%. CAS No. 219138-06-4. Molecular formula: C38H44F3N5O12. Mole weight: 819.78.
z-Val-gly-gly-obzl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-VAL-GLY-GLY-OBZL;Z-L-VALYL-L-GLYCYL GLYCINE BENZYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 72722-19-1. Molecular formula: C24H29N3O6. Mole weight: 455.5. Purity: 0.96. IUPACName: benzyl 2-[[2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]acetyl]amino]acetate. Density: 1.21g/cm³. Product ID: ACM72722191. Alfa Chemistry ISO 9001:2015 Certified.
Z-Val-Ile-OH
Z-Val-Ile-OH. Synonyms: Z-L-valyl isoleucine; (2S,3S)-2-((S)-2-(Benzyloxycarbonylamino)-3-Methylbutanamido)-3-Methylpentanoic Acid; Z Val Ile OH. Grade: ≥ 99% (TLC). CAS No. 41486-97-9. Molecular formula: C19H28N2O5. Mole weight: 364.44.
Z-Val-Ile-OH
Z-Val-Ile-OH. Group: Biochemicals. Alternative Names: Z-L-valyl isoleucine. Grades: Highly Purified. CAS No. 41486-97-9. Pack Sizes: 2g, 5g, 10g. US Biological Life Sciences.
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Z-Val-Ile-OH 99+%
Z-Val-Ile-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 10g. US Biological Life Sciences.
Z-Val-Ser-OH. Group: Biochemicals. Alternative Names: Z-L-valyl-L-serine. Grades: Highly Purified. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
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Z-Val-Ser-OH 98+% (HPLC)
Z-Val-Ser-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
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Z-Val-Trp-OH
Z-Val-Trp-OH. Synonyms: (S)-2-((S)-2-(benzyloxycarbonylamino)-3-methylbutanamido)-3-(1H-indol-3-yl)propanoic acid; Z Val Trp OH. Grade: ≥ 99% (TLC). CAS No. 18904-53-5. Molecular formula: C24H27N3O5. Mole weight: 437.50.
Z-Val-Trp-OH
Z-Val-Trp-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 18904-53-5. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
Z-Val-Trp-OH 99+%
Z-Val-Trp-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Worldwide
z-Val-trp-ome
z-Val-trp-ome. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-VAL-TRP-OME. Product Category: Heterocyclic Organic Compound. CAS No. 17430-65-8. Molecular formula: C25H29N3O5. Mole weight: 451.51. Product ID: ACM17430658. Alfa Chemistry ISO 9001:2015 Certified.
z-Val-tyr-oh
z-Val-tyr-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Z-VAL-TYR-OH. Product Category: Heterocyclic Organic Compound. CAS No. 862-26-0. Molecular formula: C22H26N2O6. Mole weight: 414.45. Purity: 0.96. IUPACName: (2S)-3-(4-hydroxyphenyl)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoic acid. Canonical SMILES: CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)O)NC(=O)OCC2=CC=CC=C2. Product ID: ACM862260. Alfa Chemistry ISO 9001:2015 Certified.
Z-Val-Val-Arg-AMC
Substrate for Cathepsin S. Group: Biochemicals. Alternative Names: Benzyloxycarbonyl-L-Valyl-L-Valyl-L-Arginine 4-Methyl-Coumaryl-7-Amide, Z-Val-Val-Arg-AMC, Z-VVR-AMC, Z-VVR-MCA. Grades: Highly Purified. CAS No. 124485-41-2. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C34H45N7O7 HCl, Molecular Weight: 722.22. US Biological Life Sciences.
Worldwide
Z-Val-Val-Arg-AMC
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins [1]. Uses: Scientific research. Group: Peptides. CAS No. 124485-41-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-137367.
Z-Val-Val-Arg-AMC
Z-Val-Val-Arg-AMC is a peptide used as a selective azadipeptide nitrile inhibitor for cathepsin K. Synonyms: benzyl (S)-1-((S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamate; Z Val Val Arg AMC. Grade: 95%. CAS No. 124485-41-2. Molecular formula: C34H45N7O7. Mole weight: 663.77.
Z-VDVAD-FMK is a special inhibitor of caspase-2. Z-VDVAD-FMK produces a reduction in Lovastatin-induced apoptosis[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-VD(OMe)VAD(OMe)-FMK. CAS No. 210344-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1008.
Z-VDVAD-FMK
Z-VDVAD-FMK is a cell-permeant and irreversible caspase-2 inhibitor and can inhibits apoptosis in various cell lines. Synonyms: Z-VD(OMe)VAD(OMe)-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethyl ketone; benzyloxycarbonyl-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-|A-aspartyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK. Grade: ≥95%. CAS No. 210344-92-6. Molecular formula: C32H46FN5O11. Mole weight: 695.74.
Z-VEID-FMK
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-VE(OMe)ID(OMe)-FMK. CAS No. 210344-96-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1007.
Z-VRPR-FMK trifluoroacetate salt
Z-VRPR-FMK trifluoroacetate salt is an irreversible and cell-permeable MALT1 inhibitor. Z-VRPR-FMK dose-dependently inhibits T cell activation-induced cleavage of Bcl-10. Z-VRPR-FMK reduces NF-κB-dependent gene expression in lymphocytes. Synonyms: Z-Val-Arg-Pro-DL-Arg-FMK. Grade: >90%. Molecular formula: C31H49FN10O6.CF3CO2H. Mole weight: 790.81.
Z-VRPR-FMK (Z-Val-Arg-Pro-DL-Arg-FMK. TFA)
Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-kappaB-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma (GCB-DLBCL) cell lines. Shown to inhibit the autoprocessing activity of MCA2ac (calcium dependent) in Trypanosoma brucei. Group: Biochemicals. Grades: Purified. CAS No. 1381885-28-4 (free base). Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
Worldwide
ZW4864
ZW4864 is an orally active and selective ? catenin/B-Cell lymphoma 9 protein protein interaction (? catenin/BCL9 PPI) inhibitor. ZW4864 inhibits ? catenin/BCL9 PPI with a Ki value of 0.76 ?M and an IC50 value of 0.87 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2632259-93-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132300.
ZX-29
ZX-29 is a potent and selective ALK inhibitor for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX-29 is inactive against EGFR. ZX-29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX-29 also induces protective autophagy and has antitumor effect. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZX-29; ZX29; ZX 29. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2254805-62-2. Molecular formula: C23H28ClN7O3S. Mole weight: 518.03. Purity: >98%. IUPACName: N-(2-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide. Canonical SMILES: CS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3OC)=NC=C2Cl)=O. Product ID: ACM2254805622. Alfa Chemistry ISO 9001:2015 Certified. Categories: ZH-29.
ZXH-3-26
ZXH-3-26 is a PROTAC connected by ligands for Cereblon and BRD4 with a DC50/5h of 5 nM. The DC50/5h refers to half-maximal degradation after 5 hours of treatment of ~ 5 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2243076-67-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122826.
ZY-444
ZY-444 is a small molecule that suppresses breast cancer progression by targeting pyruvate carboxylase. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802650-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142870.
Zygadenine
Zygadenine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Zygadenine;4α,9-Epoxycevane-3β,4,14,15α,16β,20-hexol. Product Category: Heterocyclic Organic Compound. CAS No. 545-45-9. Product ID: ACM545459. Alfa Chemistry ISO 9001:2015 Certified.
Zygosporin D
Zygosporin D is produced by the strain of Zygosporium masonii MFC-612 and Zygosporium mycophylum MFC-702. It is cytotoxic to HeLa cells with ED50 of 0.4 μg/mL. It has anti-tumor and anti-inflammatory properties. Synonyms: Desacetylcytochalasin D; Deactylzygosporin A; (7S,13E,16S,18R,19E,21R)-7,18,21-Trihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione; 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-. CAS No. 25374-67-8. Molecular formula: C28H35NO5. Mole weight: 465.58.
Zygosporin E
Zygosporin E is produced by the strain of Zygosporium masonii MFC-612 and Zygosporium mycophylum MFC-702. It is cytotoxic to HeLa cells with ED50 of 0.4 μg/mL. It has anti-tumor and anti-inflammatory properties. Synonyms: (7S,13E,16S,18S,19E,21R)-21-Acetoxy-7-hydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione; 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6-hydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12S,13E,15R,15aR)-; Z-Val-Lys-Met 7-amido-4-methylcoumarin; Z-Val-Lys-Met-MCA. CAS No. 26399-27-9. Molecular formula: C30H37NO5. Mole weight: 491.62.