A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PI(4,5)P2 is a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. Alternative Names: 1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt); 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-4,5-bisphosphate] (ammonium salt); PIP2[4',5'](18:1(9Z)/18:1(9Z)) (ammonium salt). Grades: >99%. CAS No. 799268-56-7. Molecular formula: C45H94N3O19P3. Mole weight: 1074.16.
18:1 PI(4)P
18:1 PI(4)P, a phosphatidylinositol lipid molecule, intricately participates in various cell signaling cascades. Its indispensable involvement in modulating cellular functions, including vesicular transport, cytoskeletal dynamics, and cellular proliferation, signifies its crucial significance. The therapeutic potential of 18:1 PI(4)P extends to combating multifaceted diseases like cancer, Alzheimer's disease, and diabetes. Alternative Names: 1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) (ammonium salt). Grades: >99%. CAS No. 1803104-55-3. Molecular formula: C45H84O16P2. Mole weight: 943.09.
18:1 PI(5)P ammonium salt
The 18:1 PI(5)P ammonium salt is a crucial phosphatidylinositol (PI) derivative utilized in research to investigate intricate cellular signaling pathways. There is compelling evidence suggesting its potential role in the regulation of a myriad of diseases, including but not limited to cancer, diabetes, and neurodegenerative disorders. Alternative Names: 1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) (ammonium salt); PIP[5'](18:1/18:1). Grades: >99%. CAS No. 1246303-10-5. Molecular formula: C45H90N2O16P2. Mole weight: 977.15.
18:1 Ptd Ethylene Glycol (sodium salt)
18:1 Ptd Ethylene Glycol (sodium salt) is used in the biomedical industry for the treatment of various diseases such as cancer, diabetes, and neurological disorders. Acts as a therapeutic agent targeting specific cellular pathways for effective disease management. Alternative Names: 1,2-Dioleoyl-sn-Glycero-3-Phospho(Ethylene Glycol) (Sodium Salt); 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho(ethylene glycol) (sodium salt). Grades: >99%. CAS No. 474923-51-8. Molecular formula: C41H76NaO9P. Mole weight: 767.00.
18:1 SM (d18:1/18:1(9Z))
18:1 SM (d18:1/18:1(9Z)) epitomizes a sphingomyelin lipid molecular entity pivotal in biomedicine; rendering therapeutics for neurological maladies and inflammation. Its indispensable involvement in cellular communication and membrane architecture underscores its significance in pharmaceutical compositions tailored for said ailments. Alternative Names: N-oleoyl-D-erythro-sphingosylphosphorylcholine; Oleoyl Sphingomyelin; N-(9Z-octadecenoyl)-sphing-4-enine-1-phosphocholine; C18:1 Sphingomyelin; N-(9Z-octadecenoyl)-sphing-4-enine-1-phosphocholine; SM(d18:1/18:1(9Z)). Grades: >99%. CAS No. 108392-10-5. Molecular formula: C41H81N2O6P. Mole weight: 729.08.
18:1 stigmasteryl glucose
18:1 stigmasteryl glucose. Alternative Names: 3-O-[(6'-O-oleoyl)-β-D-glucopyranosyl] stigmasterol. CAS No. 111103-97-0. Purity: >99%. Product ID: ALCFA111103970. Molecular formula: C53H90O7. Mole weight: 839.278. Alfa Chemistry - ISO 9001:32057 Certified.
18:2 cholesteryl-d7 ester. Alternative Names: cholesteryl-d7 linoleate. CAS No. 1416275-36-9. Purity: >99%. Product ID: ALCFA1416275369. Molecular formula: C45H69D7O2. Mole weight: 656.14. Alfa Chemistry - ISO 9001:32057 Certified.
18:2 Lyso PA (sodium salt)
Lysophosphatidic acid (LPA) belongs to a class of phospholipids that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a free hydroxyl and phosphate moiety. It is the major constituent of serum. 18:2 Lysophosphatidic acid (LPA) is an active ingredient of gintonin, which is a bioactive ligand of ginseng. Alternative Names: 1-linoleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); 1-(9Z,12Z-octadecadienoyl)-2-hydroxy-sn-glycero-3-phosphate (sodium salt); PA(18:2(9Z,12Z)/0:0) (sodium salt). Grades: >99%. CAS No. 65528-85-0. Molecular formula: C21H38NaO7P. Mole weight: 456.49.
18:2 TAP chloride salt
18:2 TAP chloride salt is a cationic lipid characterized by an 18-carbon, two-double-bond (linoleic acid-like) tail and a trimethylammonium propane head group, forming a chloride salt. This compound is useful in biochemical research, particularly in studies involving lipid membranes, vesicle formation, and drug delivery systems due to its ability to interact with negatively charged molecules and membranes. Alternative Names: 1,2-dilinoleoyl-3-trimethylammonium-propane chloride salt; 18:2 TAP; 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-, chloride (1:1); 1,2-Dilinoleoyl-3-trimethylaminopropane chloride salt; N,N,N-trimethyl-2,3-bis(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)propan-1-aminium chloride salt; N,N,N-Trimethyl-2,3-bis[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-1-propanaminium chloride salt; TAP-18:2 chloride. Grades: ≥95%. CAS No. 1169768-16-4. Molecular formula: C42H76ClNO4. Mole weight: 694.51.
18:2 TopFluor® cholesterol
It is a cholesterol analog containing unsaturated (18:2) acyl chain and can be used to study the diffusion of cholesterol analogs compared with phospholipid analogs in model membranes. Alternative Names: 23-(dipyrrometheneboron difluoride)-24-norcholesteryl linoleate. Grades: >99%. CAS No. 2260795-60-4. Molecular formula: C54H81BF2N2O2. Mole weight: 839.04.
187-1, N-WASP inhibitor can inhibit neural Wiskott-Aldrich syndrome protein by stabilizing the autoinhibited state of the protein. It can also block phosphatidylinositol 4,5-bisphosphate (PIP2)-stimulated actin assembly with an IC50 value of~ 2 μM. Alternative Names: n-wasp-inhibitor,187-1; cyclo[Gln-Lys-D-Phe-D-Pro-D-Phe-Phe-D-Pro-Gln-Lys-D-Phe-D-Pro-D-Phe-Phe-D-Pro]; cyclo[L-glutaminyl-L-lysyl-D-phenylalanyl-D-prolyl-D-phenylalanyl-L-phenylalanyl-D-prolyl-L-glutaminyl-L-lysyl-D-phenylalanyl-D-prolyl-D-phenylalanyl-L-phenylalanyl-D-prolyl]. Grades: >98%. CAS No. 380488-27-7. Molecular formula: C96H122N18O16. Mole weight: 1784.13.
187-1, N-WASP inhibitor
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 380488-27-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1045.
1,8,9-Triacetoxyanthracene
1,8,9-Triacetoxyanthracene. Alternative Names: 1,8,9-triacetoxyanthracene;Triacetyldithranol;1,8,9-Anthracenetriol triacetate;Exolan. CAS No. 16203-97-7. Product ID: ACM16203977. Molecular formula: C20H16O6. Mole weight: 262.34576. Alfa Chemistry - ISO 9001:32057 Certified.
18-alpha-Glycyrrhetinic acid
18-alpha-Glycyrrhetinic acid. Alternative Names: 3beta-Hydroxy-11-oxo-18alpha,20beta-olean-12-en-29-oic acid. CAS No. 1449-05-4. Purity: >95.0%. Product ID: FFC-AR-1449054. Molecular formula: C30H46O4. Mole weight: 470.68. IUPAC Name: (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified.
18α-Glycyrrhetinic acid
18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-N0375.
18α-Glycyrrhetinic Acid
18α-Glycyrrhetinic Acid rapidly and reversibly blocks gap junction intercellular communication (GJIC). Group: Biochemicals. Grades: Highly Purified. CAS No. 1449-05-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C30H46O4. US Biological Life Sciences.
Worldwide
18α-Glycyrrhetinic Acid 3-O- β-D-Glucuronide
18α-Glycyrrhetinic Acid 3-O- β-D-Glucuronide is a metabolite of 18α-Glycyrrhetinic Acid (G735005), an anti-inflammatory which also rapidly and reversibly blocks gap junction intercellular communication (GJIC). Group: Biochemicals. Grades: Highly Purified. CAS No. 400870-85-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C36H54O10. US Biological Life Sciences.
Worldwide
18α-Glycyrrhizic acid
18α-Glycyrrhizic acid is a derivate of Glycyrrhizic acid. 18α-Glycyrrhizic acid has weak antihepatotoxic anti-inflammatory activities[1]. Uses: Scientific research. Category: Natural products. CAS No. 83896-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6911A.
18α-Glycyrrhizic Acid
18α-Glycyrrhizic Acid is a derivative of Glycyrrhizic Acid (G735150), a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 83896-44-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C42H62O16, Molecular Weight: 822.93. US Biological Life Sciences.
Worldwide
18α-Hydroxyprogesterone
18α-Hydroxyprogesterone is a steroid hormone related to Progesterone (P755900) which is produced by the corpus luteum. It induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 596-69-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C21H30O3, Molecular Weight: 330.46. US Biological Life Sciences.
Worldwide
18-Amine
18-Amine. CAS No. 124-3-1. Product ID: ACM12431. Molecular formula: C18H39N. Alfa Chemistry - ISO 9001:32057 Certified.
25g Pack Size. Group: Building Blocks, Organics. Formula: C30H46O4. CAS No. 471-53-4. Prepack ID 35554872-25g. Molecular Weight 470.69. See USA prepack pricing.
18β-Glycyrrhetinic acid
18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. Uses: Scientific research. Category: Signaling pathways. CAS No. 471-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-N0180.
18-β-Glycyrrhetinic acid methyl ester is an extensively utilized natural compound within the biomedical field manifesting a promising aptitude for studying a plethora of ailments including hepatitis, cancer and inflammation. Alternative Names: Methyl glycyrrhetinate. CAS No. 1477-44-7. Molecular formula: C31H48O4. Mole weight: 484.71.
Enoxolone is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It exhibits antiallergic, antibacterial, and antiviral properties and is commonly used for allergic or infectious skin inflammation. Enoxolone is a natural compound used in cosmetics material. Uses: The treatment of allergic or infectious skin inflammation. Alternative Names: Enoxolone; Glycyrrhetinic acid; Uralenic acid; Glycyrrhetic acid; Rhetinic Acid; 18-beta-Glycyrrhetinic acid; BRN 2229654; NSC 35347. Grades: >98%. CAS No. 471-53-4. Molecular formula: C30H46O4. Mole weight: 470.68.
1, 8-Bis (chloromethyl) naphthalene is used in the to make acenapthene by laser flash photolysis. Group: Biochemicals. Grades: Highly Purified. CAS No. 50585-29-0. Pack Sizes: 500mg, 5g. Molecular Formula: C12H10Cl2, Molecular Weight: 225.11. US Biological Life Sciences.
1,8-Bis(phenylthio)-9,10-anthracenedione. Alternative Names: SOLVENT YELLOW 163;1,8-bis(phenylthio)-9,10-anthracenedione;1,8-Bis(phenylthio)anthraquinone;AMAPLAST YELLOW GHS;1,8-bis(phenylthio)anthracene-9,10-dione;9,10-Anthracenedione, 1,8-bis(phenylthio)-;Yellow GHS;C.I.58840. CAS No. 13676-91-0. Product ID: ACM13676910. Molecular formula: C26H16O2S2. Mole weight: 424.54. Alfa Chemistry - ISO 9001:32057 Certified.
18-Bromooctadecanoic acid
18-Bromooctadecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 2536-38-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W613392.
18-carboxy dinor Leukotriene B4
18-carboxy dinor Leukotriene B4 is b-oxidation metabolite of LTB4. Group: Biochemicals. Grades: Highly Purified. CAS No. 102674-12-4. Pack Sizes: 25ug, 50ug. Molecular Formula: C18H26O6, Molecular Weight: 338.4. US Biological Life Sciences.
Inhibits both Ca2+ dependent myosin phosphorylation by MLC-Kinase and protein kinase C. Group: Biochemicals. Alternative Names: HA-156. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A heme-thiolate protein (P-450) which uses a flavodoxin-like redox partner to reduce the heme iron. Isolated from the bacterium Citrobacter braakii, which can use 1,8-cineole as the sole source of carbon. Group: Enzymes. Synonyms: P450cin; CYP176A; CYP176A1. Enzyme Commission Number: EC 1.14.13.156. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0756; 1,8-cineole 2-endo-monooxygenase; EC 1.14.13.156; P450cin; CYP176A; CYP176A1. Cat No: EXWM-0756.
1,8-cineole 2-exo-monooxygenase
A heme-thiolate protein (P-450). The mammalian enzyme, expressed in liver microsomes, performs a variety of oxidation reactions of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. cf. EC 1.14.13.97 (taurochenodeoxycholate 6-hydroxylase), EC 1.14.13.67 (quinine 3-monooxygenase) and EC 1.14.13.32 (albendazole monooxygenase). Group: Enzymes. Synonyms: CYP3A4. Enzyme Commission Number: EC 1.14.13.157. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0757; 1,8-cineole 2-exo-monooxygenase; EC 1.14.13.157; CYP3A4. Cat No: EXWM-0757.
1,8-cineole synthase
Requires Mn2+ or Zn2+. Mg2+ is less effective than either. 1,8-Cineole is the main product from the enzyme with just traces of other monoterpenoids. The oxygen atom is derived from water. The reaction proceeds via linalyl diphosphate and α-terpineol, the stereochemistry of both depends on the organism. However neither intermediate can substitute for geranyl diphosphate. The reaction in Salvia officinalis (sage) proceeds via (-)-(3R)-linalyl diphosphate while that in Arabidopsis (rock cress) proceeds via (+)-(3S)-linalyl diphosphate. Group: Enzymes. Synonyms: 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Enzyme Commission Number: EC 4.2.3.108. CAS No. 110637-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5119; 1,8-cineole synthase; EC 4.2.3.108; 110637-19-9; 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Cat No: EXWM-5119.
18-Crown-5 [4-(2,4-Dinitrophenylazo)phenol]. Uses: For analytical and research use. Alternative Names: 5-(2,4-Dinitrophenylazo)-2-hydroxy-1,3-xylylene-18-crown 5-Ether. CAS No. 81238-58-6. Molecular formula: C22H26N4O10. Mole weight: 506.47. Catalog: APB81238586.
18-Crown-6
A useful phase transfer catalyst. Group: Biochemicals. Grades: Highly Purified. CAS No. 17455-13-9. Pack Sizes: 1g, 10g, 25g, 50g, 100g. Molecular Formula: C??H??O?. US Biological Life Sciences.
Worldwide
18-Crown-6
25g Pack Size. Group: Biochemicals, Ligands. Formula: C12H24O6. CAS No. 17455-13-9. Prepack ID 27395735-25g. Molecular Weight 264.32. See USA prepack pricing.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 60ul. US Biological Life Sciences.
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
1,8-Diamino-4,5-dihydroxyanthraquinone
1,8-Diamino-4,5-dihydroxyanthraquinone. Alternative Names: 1,8-diamino-4,5-dihydroxy-10-anthracenedione; 1,8-Diamino-4,5-dihydroxy-9,10-anthracenedione; 1,8-diamino-4,5-dihydroxy-9,10-anthraquinone; 1,8-diamino-4,5-dihydroxyanthrachinon; 1,8-diamino-4,5-dihydroxy-anthraquinon; 1,8-diaminochrysazine; 1,8-dihydroxy-4,5-. CAS No. 128-94-9. Molecular formula: C14H10N2O4. Mole weight: 270.24.
1,8-Diaminochrysazine
1,8-Diaminochrysazine is an intermediate in the synthesis of compounds used to disperse dye for synthetic polyester fibers. Group: Biochemicals. Grades: Highly Purified. CAS No. 128-94-9. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H10N2O4. US Biological Life Sciences.
Worldwide
1,8-Diaminonaphthalene
1,8-Diaminonaphthalene is used as a reagent/ligand in the synthesis of transition metal tetraazamacrocyclic complexes as potent antimicrobial and antioxidant agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 479-27-6. Pack Sizes: 25g, 100g. Molecular Formula: C10H10N2, Molecular Weight: 158.199999999999. US Biological Life Sciences.
Worldwide
1,8-Diaminonapthalene
Diaminonapthalene. CAS No. 479-27-6. Categories: 1,8-diaminonaphthalene; naphthalene-1,8-diamine.
Pennsylvania PA
1,8-Diaminooctane
1,8-Diaminooctane. Alternative Names: 8-Diaminooctane. CAS No. 373-44-4. Molecular formula: C8H20N2. Mole weight: 144.26. Purity: 98%. SMILES: C(CCCCN)CCCN. InChI: InChI=1S/C8H20N2/c9-7-5-3-1-2-4-6-8-10/h1-10H2.
1,8-Diaminooctane (CAS# 373-44-4) is a useful research chemical compound. Uses: Used to produce fungicides. Alternative Names: octane-1,8-diamine. Grades: 98 %. CAS No. 373-44-4. Molecular formula: C8H20N2. Mole weight: 144.26.
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptide synthesis. Alternative Names: NH2-(CH2)8-NH-Trt-Resin; Diaminooctane-Trt-Resin.