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A intermediate in the synthesis of Taxol and derivatives. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
10-deacetylbaccatin III 10-O-acetyltransferase
The enzyme will not acylate the hydroxy group at 1β, 7β or 13α of 10-deacetyl baccatin III, or at 5α of taxa-4(20),11-dien-5α-ol. May be identical to EC 2.3.1.163, 10-hydroxytaxane O-acetyltransferase. Group: Enzymes. Enzyme Commission Number: EC 2.3.1.167. CAS No. 220946-63-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2107; 10-deacetylbaccatin III 10-O-acetyltransferase; EC 2.3.1.167; 220946-63-4. Cat No: EXWM-2107.
10-Deacetyl Cephalomannine
10-Deacetyl Cephalomannine is a derivative of Cephalomannine. Group: Biochemicals. Alternative Names: (αR, βS)-α-Hydroxy- β - [ [ (2E) -2-methyl-1-oxo-2-buten-1-yl] amino] benzenepropanoic Acid (2aR, 4S, 4aS, 6R, 9S, 11S, 12S, 12aR, 12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11, 12, 12a, 12b-dodecahydro-4, 6, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3, 4]benz[1, 2-b]oxet-9-yl Ester; 10-Deacetyltaxol B; 10 β-Deacetylcephalomanine. Grades: Highly Purified. CAS No. 76429-85-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
10-Deacetyl Cephalomannine
10-Deacetyl Cephalomannine is a derivative of Cephalomannine. Synonyms: (αR,βS)-α-Hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-meth. Grade: > 95%. CAS No. 76429-85-1. Molecular formula: C43H51NO13. Mole weight: 789.88.
10-Deacetyl Paclitaxel Ethyl Analogue
An impurity of Paclitaxel which is the first taxane in clinical trials as a chemotherapy medicine. Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-4,6,11-trihydroxy-9-(((2R,3S)-2-hydroxy-3-phenyl-3-propionamidopropanoyl)oxy)-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate; 10-Deacetyl-3'-debenzoyl-3'-propanoylpaclitaxel. Grade: > 95%. CAS No. 173101-59-2. Molecular formula: C41H49NO13. Mole weight: 763.85.
10-Deacetyl Paclitaxel Propyl Analogue
An impurity of Paclitaxel which induces the expression of the gene for tumor necrosis factor α. Synonyms: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-butyramido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Benzoate; 10-Deacetyl-3'-debenzoyl-3'-butanoylpaclitaxel. Grade: > 95%. CAS No. 173101-47-8. Molecular formula: C42H51NO13. Mole weight: 777.87.
10-Deacetyltaxol
10-Deacetyltaxol. Group: Biochemicals. Grades: Plant Grade. CAS No. 78432-77-6. Pack Sizes: 20mg. Molecular Formula: C45H49NO13, Molecular Weight: 811.87. US Biological Life Sciences.
Worldwide
10-Deacetyltaxol
10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc[1]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro[2]. 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 10-Deacetylpaclitaxel. CAS No. 78432-77-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1391.
10-Deacetylyunnanxane
10-Deacetylyunnanxane is extracted from the roots of Taxus x media. Synonyms: 10-Deacetylyunnanxane; 1333323-17-3; [(1S,2S,3S,5S,8S,10S,14S)-2,5-diacetyloxy-10-hydroxy-8,12,15,15-tetramethyl-4-methylidene-14-tricyclo[9.3.1.03,8]pentadec-11-enyl] (2R,3S)-3-hydroxy-2-methylbutanoate. Grade: 96.5%. CAS No. 1333323-17-3. Molecular formula: C29H44O8. Mole weight: 520.66.
10-DEBC
10-DEBC is a selective and reversible Akt/PKB inhibitor that inhibits IGF-1-stimulated Akt phosphorylation and activation, and downstream activation of mTOR, p70 S6 kinase, and S6 ribosomal protein. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine; 10-DEBC free base; Akt Inhibitor X; CCG-206734; NCP. Grade: ≥95%. CAS No. 201788-90-1. Molecular formula: C20H25ClN2O. Mole weight: 344.88.
10-DEBC hydrochloride
10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34.
10-DEBC hydrochloride
Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences.
Worldwide
10-DEBC hydrochloride
10-DEBC hydrochloride is a selective Akt inhibitor, with an IC50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 925681-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-100654.
10-Decarbamoyloxy-9-dehydromitomycin B
10-Decarbamoyloxy-9-dehydromitomycin B is a mitane antibiotic produced by Streptomyces caespitosus KY 2072. It has anti-Gram-positive bacteria and anti-tumor cell activity. Synonyms: Mitomycin H; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxy-8-methylene-, (1aS-(1a-alpha,8a-alpha,8b-alpha))-. CAS No. 74148-44-0. Molecular formula: C15H16N2O4. Mole weight: 288.30.
10-Decarbomethoxyaclacinomycin A
10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. It has anti-tumor and gram-positive bacteria activity. Synonyms: 7-epi-10-Decarbomethoxyaclacinomycin A. CAS No. 76264-91-0. Molecular formula: C40H51NO13. Mole weight: 753.83.
10-Deoxo-9,10-dehydro ketotifen
10-Deoxo-9,10-dehydro ketotifen. Group: Biochemicals. Alternative Names: 4-(4H-Benzo[4, 5]cyclohepta[1, 2-b]thien-4-ylidene)-1-methylpiperidine. Grades: Highly Purified. CAS No. 4673-38-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H19NS. US Biological Life Sciences.
Worldwide
10-Deoxymethymycin
It is produced by the strain of Streptomyces venezuelae. 10-Deoxymethymycin is a biochemical. Synonyms: Antibiotic YC 17; YC-17. Grade: >98%. CAS No. 11091-33-1. Molecular formula: C25H43NO6. Mole weight: 453.61.
10-deoxymethynolide desosaminyltransferase
DesVII is the glycosyltransferase responsible for the attachment of dTDP-D-desosamine to 10-deoxymethynolide or narbonolide during the biosynthesis of methymycin, neomethymycin, narbomycin, and pikromycin in the bacterium Streptomyces venezuelae. Activity requires an additional protein partner, DesVIII. Group: Enzymes. Synonyms: glycosyltransferase DesVII; DesVII. Enzyme Commission Number: EC 2.4.1.277. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2509; 10-deoxymethynolide desosaminyltransferase; EC 2.4.1.277; glycosyltransferase DesVII; DesVII. Cat No: EXWM-2509.
10-deoxymethynolide synthase
The product, 10-deoxymethynolide, contains a 12-membered ring and is an intermediate in the biosynthesis of methymycin in the bacterium Streptomyces venezuelae. The enzyme also produces narbonolide (see EC 2.3.1.240, narbonolide synthase). The enzyme has 29 active sites arranged in four polypeptides (pikAI - pikAIV) with a loading domain, six extension modules and a terminal thioesterase domain. Each extension module contains a ketosynthase (KS), keto reductase (KR), an acyltransferase (AT) and an acyl-carrier protein (ACP). Not all active sites are used in the biosynthesis. Group: Enzymes. Synonyms: pikromycin PKS. Enzyme Commission Number: EC 2.3.1.239. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2187; 10-deoxymethynolide synthase; EC 2.3.1.239; pikromycin PKS. Cat No: EXWM-2187.
10-Desacetyl paclitaxel
10-Desacetyl paclitaxel. Group: Biochemicals. Alternative Names: 10-Deacetylpaclitaxel; 10-Deacetyltaxol; 10-Desacetyltaxol. Grades: Highly Purified. CAS No. 78432-77-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C45H49NO13. US Biological Life Sciences.
Worldwide
10-Desmethoxycolchicoside
10-Desmethoxycolchicoside is an impurity of Thiocolchicoside, a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Synonyms: 10-Desmethoxycolchiside; N-((S)-1,2-Dimethoxy-9-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide; N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide. Molecular formula: C26H31NO10. Mole weight: 517.53.
10-Desmethoxycolchiside
10-Desmethoxycolchiside is an impurity of Thiocolchicoside (T344385), a GABA receptor antagonist which is prescribed as a muscle relaxant having analgesic effects. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H31NO10. US Biological Life Sciences.
Worldwide
10'-Desmethoxystreptonigrin
It is a close analogue of streptonigrin produced by selected streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. It has potent and broad spectrum antibacterial and antitumour activity. Synonyms: 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl-; 10-Desmethoxystreptonigrin. Grade: >95% by HPLC. CAS No. 136803-89-9. Molecular formula: C24H20N4O7. Mole weight: 476.44.
10-Despiperazino-10-fluoro Marbofloxacin
10-Despiperazino-10-fluoro Marbofloxacin is an intermediate in the synthesis of Marbofloxacin (M197000); a fluorinated quinolone antibacterial. Group: Biochemicals. Grades: Highly Purified. CAS No. 115551-41-2. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C12H8F2N2O4, Molecular Weight: 282.2. US Biological Life Sciences.
Worldwide
10-Dihydrosteffimycin A
It is produced by the strain of Actinoplanes utahensis. 10-Dihydrosteffimycin A has anti-gram-positive bacterial activity. Synonyms: 3,4,10,12-tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2-O-methylhexopyranoside. CAS No. 75086-96-3. Molecular formula: C28H32O13. Mole weight: 576.54.
10-Dihydrosteffimycin B
It is produced by the strain of Chaetomium sp. BB 427. 10-Dihydrosteffimycin B has anti-gram-positive bacterial activity. Synonyms: 3,4,10,12-Tetrahydroxy-2,8-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 6-deoxy-2,4-di-O-methylhexopyranoside. CAS No. 75086-97-4. Molecular formula: C29H34O13. Mole weight: 590.57.
10(E),12(Z)-Conjugated linoleic acid
Conjugated linoleic acid (CLA) refers to a family of 8 geometric isomers of linoleic acid in which the two double bonds are contiguous. (The predominant form of linoleic acid in nature, 18:ω6, has double bonds at 9 and 12, interrupted by a methylene carbon.) CLA is found in both meat and dairy products, but it is not found to any significant degree in plants. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites. Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation. Synonyms: 10E,12Z-CLA; 10E,12Z-octadecadienoic acid. Grade: ≥98%. CAS No. 2420-56-6. Molecular formula: C18H32O2. Mole weight: 280.5.
10EO-Bisphenol A Diacrylate
10EO-Bisphenol A Diacrylate.
10EO Bisphenol A Dimethacrylate
10EO Bisphenol A Dimethacrylate.
10EO-BPADA
10EO-BPADA. Mole weight: 776.
10EO Hydroxyethyl Methacrylate
10EO Hydroxyethyl Methacrylate.
10-epi-Docetaxel
10-epi-Docetaxel is an isomer of Docetaxel, which is a semisynthetic derivative of Paclitaxel used to treat a variety of cancers, including breast, head and neck, stomach, prostate, and non-small cell lung cancer. Synonyms: [(1S,2S,3R,4S,7R,9S,10S,12S,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate; (2α,5β,7β,10α,13α)-4-Acetoxy-1,7,10-trihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate; Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6S,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-. Molecular formula: C43H53NO14. Mole weight: 807.88.
10-epi-γ-eudesmol synthase
The recombinant enzyme from ginger (Zingiber zerumbet) gives 62.6% β-eudesmol, 16.8% 10-epi-γ-eudesmol, 10% α-eudesmol, and 5.6% aristolene. cf. EC 4.2.3.68 (β-eudesmol synthase) and EC 4.2.3.85 (α-eudesmol synthase). Group: Enzymes. Enzyme Commission Number: EC 4.2.3.84. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5247; 10-epi-γ-eudesmol synthase; EC 4.2.3.84. Cat No: EXWM-5247.
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor. Synonyms: 10-Fddf; N-(4-{[(2-Amino-4-hydroxyquinazolin-6-yl)methyl](formyl)amino}benzoyl)-L-glutamic acid; NSC 278167; (S)-2-(4-(N-((2-Amino-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)formamido)benzamido)pentanedioic acid; N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-quinazolinyl)methyl)formylamino)benzoyl)-L-glutamic acid. Grade: ≥95%. CAS No. 61038-31-1. Molecular formula: C22H21N5O7. Mole weight: 467.43.
10-Formyl-5,8-dideazafolic acid
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 61038-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143207.
10-Formyl-7,8-dihydro Folic Acid
10-Formyl-7,8-dihydro Folic Acid is an impurity of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid; N-[p-[N-[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]glutamic Acid; N-(10-formyl-7,8-dihydropteroyl)-L-glutamate; N-Formyl-7,8-dihydrofolic Acid; 10-FDHFA; Folinic Acid Impurity F; L-Glutamic acid, N-[4-[[(2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-; 10-Formyldihydrofolate; 10-formyldihydrofolic acid; 10-Formyldihydropteroylglutamate. Grade: ≥95%. CAS No. 28459-40-7. Molecular formula: C20H21N7O7. Mole weight: 471.43.
10-Formyl-7,8-dihydro Folic Acid Disodium Salt
10-Formyl-7,8-dihydro Folic Acid Disodium Salt is an impurity of Folic acid, which is used to treat anemia caused by folate deficiency. Synonyms: N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid Disodium Salt; N-[p-[N-[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]glutamic Acid Disodium Salt; N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-L-glutamic Acid Disodium Salt; N-Formyl-7,8-dihydrofolic Acid Disodium Salt; 10-FDHFA Disodium Salt; Folinic Acid Impurity F Disodium Salt; L-Glutamic acid, N-[4-[[(2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]-, sodium salt (1:2). Grade: 85%. Molecular formula: C20H19N7Na2O7. Mole weight: 515.39.
10-Formyltetrahydrofolic acid disodium
10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 914800-65-0. Pack Sizes: 1 mg. Product ID: HY-112169A.
10-formyltetrahydropteroyl-gamma-glutamylglutamic acid. CAS No. 29552-62-3. Product ID: ACM29552623. Alfa Chemistry - ISO 9001:32057 Certified.
10-Gingerol
10-Gingerol. Group: Biochemicals. Alternative Names: (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone. Grades: Highly Purified. CAS No. 23513-15-7. Pack Sizes: 5mg, 10mg, 20mg, 50mg, 100mg. Molecular Formula: C21H34O4. US Biological Life Sciences.
Worldwide
10-Gingerol
10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23513-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0448.
10-Gingerol
10-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity. lt effectively inhibited the growth of these oral pathogens. lt inhibited exogenous ghrelin deacylation. lt induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells. It has anti-neuroinflammatory capacity. Synonyms: (+)-(S)-[10]-Gingerol; (S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone; (5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one. Grade: >98%. CAS No. 23513-15-7. Molecular formula: C21H34O4. Mole weight: 350.49.
10-Guanidinodecanoic Acid
Blood glucose-lowering compound; hypoglycemic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 73427-68-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H23N3O2, Molecular Weight: 229.32. US Biological Life Sciences.
10-hydroperoxy-8,12-octadecadienoic acid. CAS No. 90540-32-2. Product ID: ACM90540322. Molecular formula: C18H32O4. Alfa Chemistry - ISO 9001:32057 Certified.
10-Hydroxy-11-methoxycamptothecin
10-Hydroxy-11-methoxycamptothecin can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H18N2O6, Molecular Weight: 394.38. US Biological Life Sciences.
Worldwide
10-Hydroxy-11-methoxycamptothecin-d3
10-Hydroxy-11-methoxycamptothecin-d3 is the labelled version of 10-Hydroxy-11-methoxycamptothecin (H949833) which can be obtained from (S)-(+)-Camptothecin (C175150) which is an antitumor alkaloid. It binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C21H15D3N2O6, Molecular Weight: 397.4. US Biological Life Sciences.
10-hydroxy-11-(piperidin-1-yl)undecanoic acid hydrochloride. CAS No. 1296197-35-7. Product ID: ACM1296197357. Alfa Chemistry - ISO 9001:32057 Certified.
10-Hydroxy-12(Z)-octadecenoic acid
10-Hydroxy-12(Z)-octadecenoic acid is a hydroxy-unsaturated fatty acid that can be found in microorganisms such as lactic acid bacteria. Uses: Scientific research. Category: Signaling pathways. CAS No. 34932-12-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-165772.
10-Hydroxy-16-epiaffinine
10-Hydroxy-16-epiaffinine is isolated from the herbs of Rauvolfia verticillata. Synonyms: 10-Hydroxy-16-epiaffinine. Grade: > 95%. CAS No. 82513-70-0. Molecular formula: C20H24N2O3. Mole weight: 340.4.
10-Hydroxy-2-decenoic acid
10-Hydroxy-2-decenoic acid (10-HDA) is an orally active unsaturated medium-chain fatty acid with various physiological activities. 10-Hydroxy-2-decenoic acid induces ROS-mediated apoptosis in A549 cells. 10-Hydroxy-2-decenoic acid inhibits VEGF-induced angiogenesis in human venous endothelial cells. 10-Hydroxy-2-decenoic acid alleviates non-alcoholic fatty liver disease (NAFLD) by activating the AMPK-α signaling pathway. 10-Hydroxy-2-decenoic acid protects against bone loss by inhibiting NF-κB signaling downstream of FFAR4. 10-Hydroxy-2-decenoic acid is an antibiotic against many bacteria and fungi, such as Neurospora sitophila, molds and Staphylococcus aureus. 10-Hydroxy-2-decenoic acid has longevity-promoting effects in C. elegans. 10-Hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence[1][2][3][4][5][6][7][8][9][10]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 10-HDA; Queen Bee Acid. CAS No. 765-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg. Product ID: HY-W592871.
10-Hydroxy-2-decenoic acid
10-Hydroxy-2-decenoic acid. Alternative Names: 1-Hydroxy-2-decenoicacid. CAS No. 765-01-5. Product ID: CI-OT-0106. Molecular formula: C10H18O3. Alfa Chemistry - ISO 9001:32057 Certified.
10-Hydroxy-2-decenoic acid
10-Hydroxy-2-decenoic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 14113-05-4. Pack Sizes: 50mg, 250mg. Molecular Formula: C10H18O3. US Biological Life Sciences.
10-Hydroxy-5,9-dimethoxy-2H-pyrano[2,3,4-kl]xanthen-2-one is a natural product isolated from Exostema caribaeum and Hintonia latiflora plants that acts as uncoupler in spinach chloroplasts. Group: Biochemicals. Grades: Highly Purified. CAS No. 112078-70-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C17H12O6, Molecular Weight: 312.27. US Biological Life Sciences.
10-Hydroxy-9-[ (dimethylamino)methyl]-5-ethoxy- (20S, 5RS)-camptothecin is an impurity of Topotecan (T542500), a chemotherapy agent that is a topoisomerase 1 inhibitor. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-12-ethoxy-4-ethyl-4, 9-dihydroxy-1H-pyrano[3', 4': 6, 7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione. Grades: Highly Purified. CAS No. 504413-76-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
10-Hydroxy Aconitine
10-Hydroxy Aconitine is a toxic constituent from aconitum plants and known for its effects against rheumatism and rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 41849-35-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C34H47NO12, Molecular Weight: 661.74. US Biological Life Sciences.
Worldwide
10-Hydroxy Amitriptyline
A metabolite of Amitriptyline. Group: Biochemicals. Alternative Names: 5-[3- (Dimethylamino) propylidene]-10, 11-dihydro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
10-Hydroxybenzo [h]quinoline-7-sulfonate Sodium Salt
10-Hydroxybenzo [h]quinoline-7-sulfonate is used as a fluorescence method for the determination of beryllium and beryllium oxide particles. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C13H8NNaO4S. US Biological Life Sciences.
Worldwide
10-Hydroxy Cabotegravir
10-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences.
Worldwide
10-Hydroxy Cabotegravir-d3
10-Hydroxy Cabotegravir-d3 is the labelled form of 10-Hydroxy Cabotegravir. 10-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences.