A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 54-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W008253.
5-Hydroxyindole-3-acetic acid 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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5-Hydroxyindole-3-acetic acid-d2
5-Hydroxyindole-3-acetic acid-d2 is the deuterium labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 56209-31-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W008253S.
5-Hydroxyindole-3-acetic acid (Standard)
5-Hydroxyindole-3-acetic acid (Standard) is the analytical standard of 5-Hydroxyindole-3-acetic acid. This product is intended for research and analytical applications. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors. Uses: Scientific research. Category: Signaling pathways. CAS No. 54-16-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008253R.
5-Hydroxyindolmycin is an antibiotic produced by the fermentation of Serptomyces griseus in the presence of 5-hydroxytryptophan or 5-hydroxyindole. It has weak anti-Gram-positive and negative bacteria activity. Molecular formula: C14H15N3O3. Mole weight: 273.29.
5-Hydroxyisofraxidin 7-β-D-Glucoside
5-Hydroxyisofraxidin 7-β-D-Glucoside is an analog of Isofraxidin 7-O-β-D-Glucoside; a derivative of Isofraxidin and a chemical constituent found in the aerial parts of Artemisia selengensis that can potentially exhibit interleukin 6 (IL-6) inhibitory activity. Alternative Names: 5-Hydroxy-6,8-dimethoxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one. CAS No. 2415434-82-9. Molecular formula: C17H20O11. Mole weight: 400.33.
5-Hydroxyisophthalic acid
5-Hydroxyisophthalic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 618-83-7. Pack Sizes: 250g, 500g. Molecular Formula: C8H6O5. US Biological Life Sciences.
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5-Hydroxyisophthalic acid
100g Pack Size. Group: Building Blocks, Organics. Formula: C8H6O5. CAS No. 618-83-7. Prepack ID 24242615-100g. Molecular Weight 182.13. See USA prepack pricing.
5-Hydroxyisophthalic acid is used as a reagent in the synthesis of silver carboxylate metal organic framework (MOF) complexes. 5-Hydroxyisophthalic Acid is also used as the starting material in the synthesis of N,N'-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide. It is a compound related to Ioversol which is a nonionic, low osmolality, radiographic contrast agent. Alternative Names: 5-Oxyisophthalic acid; 1,3-Benzenedicarboxylic acid, 5-hydroxy-. Grades: 97 %. CAS No. 618-83-7. Molecular formula: C8H6O5. Mole weight: 182.13.
5-Hydroxyisophthalic acid dimethyl ester. Group: Biochemicals. Alternative Names: Dimethyl 5-hydroxybenzene-1,3-dicarboxylate; Dimethyl 5-hydroxyisophthalate. Grades: Highly Purified. CAS No. 13036-02-7. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C10H10O5. US Biological Life Sciences.
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5-Hydroxyisoquinoline,Tech.
5-Hydroxyisoquinoline,Tech.. CAS No: 196962
Sarchem Laboratories New Jersey NJ
5-Hydroxylansoprazole
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatment of various peptic diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG1908. CAS No. 131926-98-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118283.
5-Hydroxylansoprazole
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor used to treat various peptic diseases. Lansoprazole is metabolized through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole. Category: Active pharmaceutical ingredients. CAS No. 131926-98-2. Product ID: API131926982. Molecular formula: C16H14F3N3O3S. Mole weight: 385.36.
5-Hydroxy Lansoprazole Potassium Salt
A metabolite of Lansoprazole, as gastric pump inhibitor. Group: Biochemicals. Alternative Names: 2- [ [ [3-Methyl-4- (2, 2, 2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -1H-benzimidazol-5-ol Potassium Salt. Grades: Highly Purified. CAS No. 1329613-29-7. Pack Sizes: 5mg. US Biological Life Sciences.
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5-Hydroxy lansoprazole sulfide
5-Hydroxy lansoprazole sulfide. Group: Biochemicals. Alternative Names: 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzimidazol-6-ol. Grades: Highly Purified. CAS No. 131926-96-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C16H14F3N3O2S. US Biological Life Sciences.
Worldwide
5-Hydroxylecanoric acid
5-Hydroxylecanoric acid is a derivative of Lecanoric acid, which is a didepside produced by several species of lichen. Molecular formula: C16H14O8. Mole weight: 334.28.
5-Hydroxy-L-norvaline
5-Hydroxy-L-norvaline. Alternative Names: H-Nva(5-OH)-OH; H-Ser{#(CH2)2}-OH; (S)-5-Hydroxy-2-aminopentanoic acid. CAS No. 6152-89-2. Molecular formula: C5H11NO3. Mole weight: 133.15.
5-Hydroxy-L-norvaline
5-Hydroxy-L-norvaline. Alternative Names: H-Nva(5-OH)-OH. CAS No. 6152-89-2. Purity: 95%. Product ID: ACM6152892. Molecular formula: C5H11NO3. Mole weight: 133.15. Alfa Chemistry - ISO 9001:32057 Certified.
5-Hydroxy Lornoxicam
The main metabolite of Lornoxicam. Group: Biochemicals. Alternative Names: 6-Chloro-4-hydroxy-N-(5-hydroxy-2-pyridinyl)-2-methyl-. Grades: Highly Purified. CAS No. 123252-96-0. Pack Sizes: 1mg. US Biological Life Sciences.
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5-Hydroxy-L-tryptophan
5-Hydroxy-L-tryptophan. Group: Biochemicals. Alternative Names: L-Trp(5-OH)-OH; L-2-Amino-3- (5-hydroxyindolyl) propionic acid; (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid. Grades: Highly Purified. CAS No. 4350-09-8,314062-44-7. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C11H12N2O3. US Biological Life Sciences.
Worldwide
5-Hydroxy-L-tryptophan
5-Hydroxy-L-tryptophan is an intermediate in the biosynthesis of serotonin from tryptophan. It can be used as an antiepileptic and antidepressant. Nutritional supplement in health care products. Uses: Ingredient of health care products. Alternative Names: L-Tryptophan, 5-hydroxy-; Tryptophan, 5-hydroxy-, L-; (2S)-2-Azaniumyl-3-(5-hydroxy-1H-indol-3-yl)propanoate; (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid; (S)-5-Hydroxytryptophan; 5-Hydroxyl-L-tryptophan; 5-Hydroxytryptophan; L-5-HTP; L-5-Hydroxytryptophan; Cincofarm; Hydroxy-L-tryptophan; Levothym; Levotinine; Oxitriptan; Oxyfan; Pretonine; Quietim; Serotonyl; Telesol; Tript-Oh; Triptene. Grades: ≥95%. CAS No. 4350-9-8. Molecular formula: C11H12N2O3. Mole weight: 220.23.
5-Hydroxy L-Tryptophan
5-Hydroxy-L-Tryptophan is a hydroxylated metabolite of L-Tryptophan. Group: Biochemicals. Alternative Names: (S)-5-Hydroxytryptophan. Grades: Highly Purified. CAS No. 4350-9-8. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
5-Hydroxy-L-tryptophan 98+% (HPLC)
5-Hydroxy-L-tryptophan 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
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5-Hydroxy L-Tryptophan-d4 (Major)
A labeled metabolite of Tryptophan. Group: Biochemicals. Alternative Names: (S)-5-Hydroxytryptophan-d4; 5-Hydroxyl-L-tryptophan-d4; 5-Hydroxytryptophan-d4; Cincofarm-d4; L-5-HTP-d4; L-5-Hydroxytryptophan-d4; Levothym-d4; Levotinine-d4; Oxitriptan-d4; Oxyfan-d4; Pretonine-d4; Quietim-d4; Serotonyl-d4; Telesol-d4; Tript-Oh-d4; Triptene-d4. Grades: Highly Purified. CAS No. 1246818-91-6. Pack Sizes: 5mg. Molecular Formula: C??H?D?N?O?, Molecular Weight: 224.25. US Biological Life Sciences.
5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine is a profoundly effective compound, meticulously utilized for research of pernicious viral infections triggered by RNA viruses. Its exceptional antiviral characteristics stem from its remarkable affinity towards targeting specific viral enzymes, unfolding a paradigm shift towards obstructing viral replication and mitigating virus-induced pathogenesis. Alternative Names: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)-2-thiouridine; 5-(hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thio-uridine; 5-(Hydroxymethyl)-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 58479-71-3. Molecular formula: C13H18N2O6S. Mole weight: 330.36.
5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)cytidine is used in the synthesis of tRNA's anticodon stem and loop domain containing the 5-formylcytidine modification. Also, it is an intermediate used in 5-Formylcytidine synthesis, which is a modified nucleoside found at the first position of the anticodon of bovine mitochondrial tRNAMet. Alternative Names: Furo[3,4-d]-1,3-dioxole Cytidine Deriv. CAS No. 72472-12-9. Molecular formula: C13H19N3O6. Mole weight: 313.31.
5-Hydroxymethyl-2'-C-methyluridine
5-Hydroxymethyl-2'-C-methyluridine is a remarkable compound,functioning as an esteemed nucleoside analogue. It adeptly curtails viral replication while propelling disarray within the tumor cell proliferation. Alternative Names: 5-Hydroxymethyl-2'-β-C-methyluridine; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2305415-92-1. Molecular formula: C11H16N2O7. Mole weight: 288.25.
5-Hydroxymethyl-2'C-methyluridine
5-Hydroxymethyl-2'C-methyluridine is a paramount compound employed in the biomedical domain, exhibiting exceptional potential in research of a myriad of ailments, including cancer and viral infections. Unveiling its distinctive configuration and properties, this compound assumes a momentous function in the realm of pharmaceutical development and exploration.
5-Hydroxymethyl-2'-deoxycytidine
5-Hydroxymethyl-2'-deoxycytidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 7226-77-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C10H15N3O5. US Biological Life Sciences.
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5-Hydroxymethyl-2'-deoxycytidine cyclic carbamate
5-Hydroxymethyl-2'-deoxycytidine cyclic carbamate is a formidable compound, showcasing its inhibitory prowess in research of combatting specific cancer strains. This compound operates as a potent DNA demethylating compound, effectively hindering DNA methylation and consequently reawakening tumor suppressor genes. Grades: 95%. CAS No. 1257247-41-8. Molecular formula: C11H13N3O6. Mole weight: 283.24.
5-Hydroxymethyl-2'-deoxycytidine-d3
5-Hydroxymethyl-2'-deoxycytidine-d3 (5hmdC-d3) is the deuterium labeled 5-Hydroxymethyl-2'-deoxycytidine (HY-131394). 5-Hydroxymethyl-2-deoxycytidine (5hmdC) is an oxidation derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA. 5-Hydroxymethyl-2-deoxycytidine may serve as a marker of irreversibly damaged cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5hmdC-d3. CAS No. 1585142-60-4. Pack Sizes: 1 mg. Product ID: HY-W654228.
5-Hydroxymethyl-2'-deoxyuridine
5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5116-24-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-129983.
5-Hydroxymethyl-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine;5116-24-5;alpha-Hydroxythymidine;5-Hydroxymethyldeoxyuridine;2'-Deoxy-5-(hydroxymethyl)uridine;HMdU;5-HMdU;alpha-Hydroxy-thymidin;Thymidine, alpha-hydroxy-;CHEBI:61288;Uridine, 2'-deoxy-5-(hydroxymethyl)-;2'-Deoxy-5-hydroxymethyluridine;5-Hydroxymethyl-deoxyuridine;EJZ33W33JN;1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-. Grades: ≥95%. CAS No. 5116-24-5. Molecular formula: C14H11N5O2S. Mole weight: 313.34.
5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate Sodium is a nucleotide that can be used in DNA bioresearch and repair, as well as cancer treatment. It inhibits the synthesis of DNA by binding to the enzyme DNMT1 and causing it to lose its ability to produce DNA. It also suppresses RNA synthesis to induce cell death. Alternative Names: 5-Hydroxymethyl-2'-deoxyuridine 5'-monophosphate monosodium; 5-hydroxymethyl-dUMP sodium. CAS No. 160509-68-2. Molecular formula: C10H14N2NaO9P. Mole weight: 360.19.
5-Hydroxymethyl-2'-deoxyuridine-5'-Triphosphate
5-Hydroxymethyl-2'-deoxyuridine-5'-Triphosphate is a pivotal compound, holding paramount significance in DNA labeling and sequencing endeavors. Functioning as a modified nucleotide triphosphate, it exhibits competencies in assimilating within DNA during the process of polymerization, thereby facilitating the identification of DNA alterations. This invaluable compound assumes a critical role in the comprehensive exploration of epigenetic modifications and the consequential impact of oxidative stress on DNA replication and repair pathways. Alternative Names: 5-hmdUTP; 5-Hydroxymethyl-dUTP; Hydroxymethyldeoxyuridine triphosphate. Grades: ≥90% by AX-HPLC. CAS No. 14167-70-5. Molecular formula: C10H17N2O15P3. Mole weight: 498.10.
5-Hydroxymethyl-2-furaldehyde
5-Hydroxymethylfurfural, found in rhizome of Typhonium giganteum Engl in natural, has antioxidative activity and is therefore used as an acting agent in a novel anticancer infusion solution, named Karal®, and an oral supplementation. Uses: Antioxidative. Alternative Names: Glucosamine EP Impurity E; 5-hydroxy-methylfurfural. Grades: > 98 %. CAS No. 67-47-0. Molecular formula: C6H6O3. Mole weight: 126.11.
5-Hydroxymethyl-2-furaldehyde-13C6
A labeled antioxidant. Group: Biochemicals. Alternative Names: 5-(Hydroxymethyl)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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5-Hydroxymethyl-2-furaldehyde (HMF)
Melting Point: 32-33°C. Group: Biochemicals. Alternative Names: HMF. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
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5-Hydroxymethyl-2-furancarboxylic Acid
5-Hydroxymethyl-2-furancarboxylic Acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 6338-41-6. Pack Sizes: 25mg. US Biological Life Sciences.
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5-Hydroxymethyl-2-furoic acid
5-Hydroxymethyl-2-furoic acid is an antibiotic produced by Pyricularia grisea IAM 5051. It can inhibit the activity of tumor cells (SV40). Alternative Names: 5-Hydroxymethyl-2-furancarboxylic acid; Sumiki's acid. Grades: >98%. CAS No. 6338-41-6. Molecular formula: C6H6O4. Mole weight: 142.11.
5-Hydroxymethyl-2-methoxyphenylboronic acid
5-Hydroxymethyl-2-methoxyphenylboronic acid. CAS No. 1137339-94-6. Product ID: ACM1137339946. Alfa Chemistry - ISO 9001:32057 Certified.
5-Hydroxymethyl-2-methyl-furan-3-carboxylic acid methyl ester. CAS No. 15341-69-2. Product ID: ACM15341692. Molecular formula: C8H10O4. Alfa Chemistry - ISO 9001:32057 Certified.
5-Hydroxymethyl-2-methylpyridine
5-Hydroxymethyl-2-methylpyridine. Group: Biochemicals. Alternative Names: (6-Methylpyridin-3-yl)methanol; 6-Methyl-3-pyridinemethanol; 6-Methyl-3-pyridylmethanol. Grades: Highly Purified. CAS No. 34107-46-5. Pack Sizes: 250mg. US Biological Life Sciences.
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5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine
5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine is an acclaimed compound, quashing viral replication and precipitously diminishing the burden of viral entities. Alternative Names: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2095417-51-7. Molecular formula: C13H20N2O8. Mole weight: 332.31.
Intermediate in the preparation of Carvedilol (C184625). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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5-Hydroxymethyl-7-methoxybenzofuran
5-Hydroxymethyl-7-methoxybenzofuran isolated from the fruits of Zanthoxylum bungeanum. Alternative Names: (7-methoxycyclopenta[c]pyran-1-yl)methanol. Grades: 98.5%. CAS No. 831222-78-7. Molecular formula: C10H10O3. Mole weight: 178.2.
5-Hydroxymethylblasticidin S
5-Hydroxymethylblasticidin S is a broad-spectrum antibiotic produced by Streptomyces setonii. Alternative Names: 1-(4-{[3-Amino-1-hydroxy-5-(N-methylcarbamimidamido)pentylidene]amino}-2,3,4-trideoxyhex-2-enopyranuronosyl)-5-(hydroxymethyl)-4-imino-1,4-dihydropyrimidin-2-ol. CAS No. 123067-52-7. Molecular formula: C18H28N8O6. Mole weight: 452.46.
5-hydroxymethylcytidine
5-Hydroxymethylcytidine is a product in DNA hydroxymethylation. The concentrations of 5-Hydroxymethylcytidine in the brain were used for Alzheimer's disease study. Alternative Names: 5-Hydroxymethyl cytidine; Cytidine, 5-(hydroxymethyl)-; 5-(Hydroxymethyl)cytidine; 4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one; 5-hydroxymethyl-1-(β-D-ribofuranosyl)cytosine. Grades: ≥95%. CAS No. 19235-17-7. Molecular formula: C10H15N3O6. Mole weight: 273.24.
5-Hydroxymethylcytidine
5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base. It is formed from the DNA base cytosine by adding a methyl group and then a hydroxy group. It is important in epigenetics, because the hydroxymethyl group on the cytosine can possibly switch a gene on and off. It was first seen in bacteriophages in 1952.[1][2] However, in 2009 it was found to be abundant in human and mouse brains,[3] as well as in embryonic stem cells.[4] In mammals, it can be generated by oxidation of 5-methylcytosine, a reaction mediated by the Tet family of enzymes. 5-Hydroxymethylcytidine is a product in DNA hydroxymethylation. The concentrations of 5-Hydroxymethylcytidine in the brain were used to study Alzheimers disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 19235-17-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
5-(Hydroxymethyl)cytidine
5-(Hydroxymethyl)cytidine is a purine nucleoside analog that can be used in oligonucleotide synthesis. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 19235-17-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-152854.
5-Hydroxymethylcytosine
5-Hydroxymethylcytosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1123-95-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C5H7N3O2. US Biological Life Sciences.
Worldwide
5-Hydroxymethylcytosine
5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development. 5-Hydroxymethylcytosine can be used for the study of non-small cell lung cancer (NSCLC), neurodegenerative diseases (Alzheimers, Parkinsons) and hematological malignancies (acute myeloid leukemia, myelodysplastic syndromes)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 5hmC. CAS No. 1123-95-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W018324.
5-(Hydroxymethyl)cytosine
5-(Hydroxymethyl)cytosine. CAS No. 1123-95-1.
5-Hydroxymethyl-dC
It is a modified pyrimidine that is capable of producing interstrand cross-links in duplex DNA. It can be analyzed to quantify DNA hydroxymethylation levels in biological samples. Alternative Names: 5-Hydroxymethyl-2'-deoxycytidine; hm-Dcmp; 2'-deoxy-5-(hydroxymethyl)cytidine; 5-(Hydroxymethyl)deoxycytidine; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 7226-77-9. Molecular formula: C10H15N3O5. Mole weight: 257.24.
5-Hydroxymethyl-dC II-CE Phosphoramidite
5-Hydroxymethyl-dC II-CE Phosphoramidite, a frequently employed reagent in genomic research, is indispensable for synthesizing modified oligonucleotides. Its site-specific labeling aptitude benefits the subsequent detection and analysis of DNA and RNA strands. Besides, the application of 5-Hydroxymethyl-dC II-CE Phosphoramidite in anti-cancer and anti-HIV therapies development also renders it an integral tool in the medical field. Alternative Names: 5'-Dimethoxytrityl-5-hydroxymethyl-N,O-carbamoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N,5-(Carbonyloxymethylene)-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. CAS No. 1257247-42-9. Molecular formula: C41H48N5O9P. Mole weight: 785.82.
5-Hydroxymethyl-dCTP
5-Hydroxymethyl-dCTP, a nucleoside triphosphate analog, is a versatile molecular tool extensively utilized by researchers globally in DNA sequencing for molecular investigations investigating epigenetic modifications and associated mechanisms. Its applications in the diagnosis and treatment of conditions such as cancer and infectious diseases are noteworthy too. Alternative Names: 5-hme-dCTP; 5-hmdCTP; 5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate; 2'-deoxy-5-hydroxymethyl-CTP; 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate; 2'-deoxy-5-(hydroxymethyl)cytidine 5'-(tetrahydrogen triphosphate). Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N3O14P3 (free acid). Mole weight: 497.18 (free acid).
5-Hydroxymethyldeoxycytidylic acid
5-Hydroxymethyldeoxycytidylic acid, an indispensable component in the realm of biomedicine, stands as a compound of paramount importance. Renowned for its potential therapeutic value, this nucleoside analog assumes a pivotal role in combatting DNA-related ailments, encompassing malignant neoplasms and pervasive viral afflictions. Researchers earnestly employ this organic entity to unravel the intricate intricacies of DNA structure-function associations and genetic manipulation techniques. Alternative Names: 5-Hmdcyt; 5-Hydroxymethyldeoxycytidylate; 2'-deoxy-5-(hydroxymethyl)cytidine 5'-(dihydrogen phosphate). Grades: ≥95%. CAS No. 13009-95-5. Molecular formula: C10H16N3O8P. Mole weight: 337.22.