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8-Methyladenosine, a nucleoside present in diverse organisms' RNAs, holds significance in multiple biological processes, such as gene expression, mRNA stability, and translation regulation. Studies indicate that 8-Methyladenosine's aberrant expression associates with numerous ailments like viral infection, neurodegenerative disorders, and cancer, expediting the development of newer therapies. Synonyms: 8-Methyl Ado; 8-Methyl adenosine; Adenosine, 8-methyl-; (2R,3R,4S,5R)-2-(6-Amino-8-methyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 56973-12-7. Molecular formula: C11H15N5O4. Mole weight: 281.27.
8-Methyladenosine
8-Methyladenosine. Group: Biochemicals. Grades: Highly Purified. CAS No. 56973-12-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H15N5O4. US Biological Life Sciences.
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8-Methyladenosine
8-Methyladenosine is a modified adenosine nucleoside. Through methylation at the 8-position, 8-Methyladenosine confers bacterial resistance to five classes of antibiotics that bind to the ribosomal peptidyl transferase center. 8-Methyladenosine can be used in studies of antibiotic-resistant bacterial infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 56973-12-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152296.
8-Methyldecanoic acid
8-Methyldecanoic acid. Alternative Names: 8-METHYLDECANOIC ACID;Decanoic acid, 8-methyl-. CAS No. 5601-60-5. Product ID: ACM5601605-1. Molecular formula: C11H22O2. Mole weight: 186.29. Alfa Chemistry - ISO 9001:32057 Certified.
8-Methylguanosine
8-Methylguanosine is a crucial compound in biomedicine used for research purposes. It serves as a building block in the synthesis of nucleic acids and is commonly used in studies investigating RNA metabolism and epitranscriptomics. Synonyms: monomethylguanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-methyl-1H-purin-6(9H)-one. Grade: ≥95%. CAS No. 36799-17-4. Molecular formula: C11H15N5O5. Mole weight: 297.27.
8-Methylthioadenosine, an extensively researched biochemical compound, is widely employed in biomedical studies due to its involvement in diverse physiological processes. With its potential therapeutic implications in cancer, liver diseases, and immunological disorders, this nucleoside serves as a valuable asset for exploring innovative treatment strategies within the realm of biomedicine. Synonyms: 8-Methylthio-adenosine; 8-methylsulphanyladenosine; 8-MeS-adenosine; Adenosine, 8-(methylthio)-; (2R,3R,4S,5R)-2-(6-amino-8-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 29836-01-9. Molecular formula: C11H15N5O4S. Mole weight: 313.33.
8-Methylthioguanosine
8-Methylthioguanosine is a synthetic nucleoside analogue impeding viral polymerases, widely applied in the research of viral maladies encompassing hepatitis C and influenza. Synonyms: 8-Methylthio-guanosine; 8-methylsulfanyl-guanosine; 8-Methylmercapto-guanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-(methylthio)-1H-purin-6(9H)-one; 8-(Methylthio)guanosine. Grade: ≥95%. CAS No. 2104-66-7. Molecular formula: C11H15N5O5S. Mole weight: 329.33.
8-Methylxanthine
8-Methylxanthine. Group: Biochemicals. Alternative Names: 2,6-Dihydroxy-8-methylpurine. Grades: Highly Purified. CAS No. 17338-96-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C6H6N4O2. US Biological Life Sciences.
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8-Morpholinyl-GTP
8-Morpholinyl-GTP, a biochemical known for its role in G protein signaling, has gained popularity in scientific research to examine the etiology of several ailments. Studies exploring Parkinson's, Huntington's, and Alzheimer's diseases and cancer have utilized this compound due to its unique composition and performance. Researchers find its presence instrumental in determining molecular mechanisms of these diseases and uncovering effective treatment options. Synonyms: 8-Morpholinyl-guanosine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C14H23N6O15P3 (free acid). Mole weight: 608.28 (free acid).
8-M-PDOT
8-M-PDOT is a melatonin receptor agonist, with 20-fold selective for the MT2 (vs MT1) subtype (pKi = 8.23 and 8.95 at human recombinant MT1 and MT2 receptors respectively). Synonyms: 8-Methoxy-2-propionamidotetralin. Grade: ≥99% by HPLC. CAS No. 134865-70-6. Molecular formula: C14H19NO2. Mole weight: 233.31.
8-[N-(2-Diphenylmethoxyethyl)-N,N-dimethylaminium]-1,3-dimethylxanthine inner salt
An impurity of Dimenhydrinate. Dimenhydrinate is an antihistamine and anticholinergic medication primarily used to prevent and treat symptoms of motion sickness, such as nausea, vomiting, and dizziness. Synonyms: 1H-Purin-8-aminium, N-[2-(diphenylmethoxy)ethyl]-2,3,6,7-tetrahydro-N,N,1,3-tetramethyl-2,6-dioxo-, inner salt; N-[2-(Diphenylmethoxy)ethyl]-2,3,6,7-tetrahydro-N,N,1,3-tetramethyl-2,6-dioxo-1H-purin-8-aminium inner salt; Dimenhydrinate Impurity 1; 8-((2-(Benzhydryloxy)ethyl)dimethylammonio)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide. Grade: ≥95%. CAS No. 64487-94-1. Molecular formula: C24H27N5O3. Mole weight: 433.51.
8-N3-6-Biotin-10-cAMP
8-N3-6-Biotin-10-cAMP is an analogue in photoaffinity labelling of cAMP binding proteins which can be immobilized by UV light. Grade: ≥ 98% by HPLC. Molecular formula: C28H40N12O9PS ยท Na. Mole weight: 774.7.
8-N3-6-[DY-547]-AE-cAMP
8-N3-6-[DY-547]-AE-cAMP is a photosensitive analogue for photoaffinity labelling. It can be immobilized by irradiation of UV light. Synonyms: 8-Azido-N6-(2-[DY-547]-aminoethyl)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C42H48N11Na2O13PS2. Mole weight: 1056.
8-N3-cAMP
8-N3-cAMP is an analogue of cAMP binding proteins used for photoaffinity labelling. Uses: Affinity labels. Synonyms: 8- Azidoadenosine- 3', 5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 31966-52-6. Molecular formula: C10H10N8O6P ยท Na. Mole weight: 392.2.
8-N3-ε-ADP
8-N3-ε-ADP is a 8-N3-ADP analogue with photosensitive activity and a ε-ADP analogue with fluorescent property, which is used for photoaffinity labelling of ADP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem410 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C12H15N8O10P2 (free acid). Mole weight: 493.3 (free acid).
8-N3-ε-ATP
8-N3-ε-ATP is a photosensitive analogue of 8-N3-ATP as well as a fluorescent analogue of ε-ATP, which can be used for photoaffinity labelling of ATP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem412 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 66895-05-4. Molecular formula: C12H15N8O13P3 (free acid). Mole weight: 572.2 (free acid).
8-N3-ε-cAMP
8-N3-ε-cAMP is a cAMP analogue used for labelling of cAMP receptors. ε-cAMP can be fluorescent through immobilization by UV light illumination, which offers a label for cAMP receptors. Synonyms: 8-Azido-1,N6-ethenoadenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. CAS No. 60902-12-7. Molecular formula: C12H10N8O6P. Mole weight: 394.24.
8-(N-Acetylamino-L-arginine)-goserelin
8-(N-Acetylamino-L-arginine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro(Ac)-NHNHCONH2; (S)-N-((9S,12S,15R,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-15-(tert-butoxymethyl)-9-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-18-(4-hydroxybenzyl)-21-(hydroxymethyl)-28-(1H-imidazol-5-yl)-4-imino-12-isobutyl-2,11,14,17,20,23,26-heptaoxo-3,5,10,13,16,19,22,25-octaazaoctacosan-27-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C61H86N18O15. Mole weight: 1311.47.
8-NBD-cAMP
8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41.
8-NBD-cGMP
8-NBD-cGMP is a fluorescent activator of both isozymes I α and I β of cGMP-dependent protein kinase. 8-NBD-cGMP fluoresces strongly in hydrophobic environments. Synonyms: 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 115993-88-9. Molecular formula: C18H17N9NaO10PS. Mole weight: 605.41.
8-NH2-ADP is an analogue of adenosine-5'-O-diphosphate used in receptor mapping studies. Synonyms: 8- Aminoadenosine- 5'- O- diphosphate. Grade: ≥ 95% by HPLC. CAS No. 65312-53-0. Molecular formula: C10H16N6O10P2 (free acid). Mole weight: 442.2 (free acid).
8-NH2-ATP
8-NH2-ATP is an analogue of adenosine-5'-triphosphate and a metabolite of the cytotoxic nucleoside 8-aminoadenosine that can be used for receptor mapping purposes. Synonyms: 8- Aminoadenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 35874-49-8. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 522.2 (free acid).
8-Nitro-1-anthraquinonesulfonic acid
8-Nitro-1-anthraquinonesulfonic acid. Alternative Names: 9,10-dihydro-8-nitro-9,10-dioxoanthracene-1-sulphonic acid;8-nitro-9,10-dioxo-9,10-dihydroanthracene-1-sulfonic acid;9,10-Dihydro-8-nitro-9,10-dioxo-1-anthracenesulfonic acid;8-nitro-9,10-dioxo-anthracene-1-sulfonic acid;8-nitro-9,10-dioxoanthracene-1-su. CAS No. 129-37-3. Product ID: ACM129373. Molecular formula: C14H7NO7S. Mole weight: 333.27288. Alfa Chemistry - ISO 9001:32057 Certified.
8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. Synonyms: 2-Amino-8-nitro-7H-purin-6-ol. Grade: ≥95%. CAS No. 168701-80-2. Molecular formula: C5H4N6O3. Mole weight: 196.1.
8-Nitroguanine
8-Nitroguanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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8-Nitroguanine-[4,8-13C2,7-15N]
The labelled 8-nitroguanine can be used as a potential biomarker for the progression of malignant fibrous histiocytoma, a model of cancer associated with inflammation. Synonyms: 2-Amino-1,9-dihydro-8-nitro-6H-purin-6-one-4,8-13C2-7-15N; 2-Amino-1,7-dihydro-8-nitro-6H-purin-6-one-4,8-13C2-7-15N. Grade: 50%; 92.6% atom 13C & 15N. CAS No. 1215708-85-2. Molecular formula: C3[13C]2H4N5[15N]O3. Mole weight: 199.1.
8-Nitroguanosine
A highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Synonyms: 8-Nitro-D-guanosine; 2-imino-8-nitro-9-(beta-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-nitro-1H-purin-6(9H)-one. Grade: ≥95%. CAS No. 337536-53-5. Molecular formula: C10H12N6O7. Mole weight: 328.24.
8-Nitroguanosine
A highly reactive redox-active nucleic acid derivative that is is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 337536-53-5. Pack Sizes: 10mg. US Biological Life Sciences.
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8-Nitroguanosine 2',3',5'-Triacetate
8-Nitroguanosine derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Synonyms: 8-Nitroguanosine 2',3',5'-Triacetate; 1096020-95-9; [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-8-nitro-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-nitro-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate; J-002308; [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2-amino-8-nitro-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl acetate. CAS No. 1096020-95-9. Molecular formula: C16H18N6O10. Mole weight: 454.35.
8-Nitroguanosine 2',3',5'-Triacetate
8-Nitroguanosine (N496050) derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Group: Biochemicals. Grades: Highly Purified. CAS No. 1096020-95-9. Pack Sizes: 25mg. US Biological Life Sciences.
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8-Nitroisoquinolin-5-amine
8-Nitroisoquinolin-5-amine. Alternative Names: 8-NITROISOQUINOLIN-5-AMINE. CAS No. 156901-58-5. Purity: 96%. Product ID: ACM156901585. Molecular formula: C9H7N3O2. Mole weight: 189.17078. IUPAC Name: 8-nitroisoquinolin-5-amine. Alfa Chemistry - ISO 9001:32057 Certified.
8-Nitronaphthalene-1,3,6-trisulfonic acid
8-Nitronaphthalene-1,3,6-trisulfonic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 38267-31-1. Pack Sizes: 5g, 10g. US Biological Life Sciences.
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8-Nitroquinoline
8-Nitroquinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 607-35-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H6N2O2. US Biological Life Sciences.
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8-Nitroquinoline-2-carboxylic acid
8-Nitroquinoline-2-carboxylic acid. Alternative Names: 8-Nitro-2-quinolinecarboxylic acid;Einecs 239-826-3. CAS No. 15733-85-4. Product ID: ACM15733854. Molecular formula: C10H6N2O4. Alfa Chemistry - ISO 9001:32057 Certified.
8-(N,N-Dimethylaminomethyl)guanosine is a profound compound, aiding in studying the unparalleled menace of herpes simplex virus (HSV) and human cytomegalovirus (HCMV). Grade: ≥95%. Molecular formula: C13H20N6O5. Mole weight: 340.34.
8-NO2-Guo
8-NO2-Guo is used for analysis of hydrolysates of RNA stressed by nitric oxide/superoxide and peroxynitrite. Synonyms: 8- Nitroguanosine. Grade: ≥ 98% by HPLC. CAS No. 337636-63-6. Molecular formula: C10H12N6O7. Mole weight: 328.3.
8-Nonenoic Acid
Nonenoic Acid. CAS No. 31642-67-8. Categories: 8-nonenoic acidnon-8-enoic acid.
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8-O-Acetylharpagide
8-O-Acetylharpagide. Group: Biochemicals. CAS No. 6926-14-3. Pack Sizes: 5mg. US Biological Life Sciences.
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8-O-Acetyl shanzhiside methyl ester
8-O-Acetyl shanzhiside methyl ester. Group: Biochemicals. Alternative Names: Barlerin; Umbroside. Grades: Plant Grade. CAS No. 57420-46-9. Pack Sizes: 20mg. Molecular Formula: C19H28O12, Molecular Weight: 448.418. US Biological Life Sciences.