A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil. Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M4 and avanafil metabolite M16, as well as minor metabolites. Avanafil metabolite M4 inhibits PDE5 with 18% of the potency of avanafil. Grade: ≥98%. Molecular formula: C23H26ClN7O4. Mole weight: 499.95.
Avanafil Related Compound 1
Avanafil Related Compound 1 is a pivotal entity within the biomedical research, primarily employed in the synthesand exploration of Avanafil, a pharmaceutical intervention targeting erectile dysfunction. Synonyms: 4-(3-chloro-4-MethoxybenzylaMino)-5-ethoxycarbonyl-2-MethylsulfinylpyriMidine; Ethyl 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(Methylsulfinyl)pyriMidine-5-carboxylate. Grade: > 95%. CAS No. 330785-82-5. Molecular formula: C16H18ClN3O4S. Mole weight: 383.86.
Avapritinib
BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Synonyms: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Molecular formula: C26H27FN10. Mole weight: 498.56.
Avapritinib
Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V , respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-285. CAS No. 1703793-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101561.
Avarofloxacin hydrochloride
Avarofloxacin hydrochloride is an antibacterial drug agent. Uses: Avarofloxacin hydrochloride is an antibacterial drug agent. Synonyms: Avarofloxacin HCl; JNJ-Q2 hydrochloride; 7-[(3E)-3-(2-amino-1-fluoroethylidene)piperidin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid hydrochloride; JNJ-32729463 hydrochloride; JNJ 32729463 hydrochloride. Grade: >98 %. CAS No. 1001162-01-1. Molecular formula: C21H24ClF2N3O4. Mole weight: 455.89.
Avarol
Avarol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Avarol; 2-{[(1r,2s,4as,8as)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]methyl}benzene-1,4-diol; (1R-(1alpha,2beta,4abeta,8abeta))-2-((1,2,3,4,4a,7,8,8a-Octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)methyl)-1,4-benzenediol; Avrol. Product Category: Heterocyclic Organic Compound. CAS No. 55303-98-5. Molecular formula: C21H30O2. Mole weight: 314.5. Purity: 0.97. IUPACName: 2-[[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]methyl]benzene-1,4-diol. Canonical SMILES: C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C=CC(=C3)O)O)CCC=C2C)C. Density: 1.055g/cm³. Product ID: ACM55303985. Alfa Chemistry ISO 9001:2015 Certified.
Avarol
Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Group: Biochemicals. Alternative Names: NSC 306951. Grades: Highly Purified. CAS No. 55303-98-5. Pack Sizes: 1mg. Molecular Formula: C21H30O2. US Biological Life Sciences.
Worldwide
Avasimibe
Avasimibe inhibits Lipoprotein(a) accumulation in the culture media of primary monkey hepatocyte in a dose-dependent manner with 11.9% -31.3% inhibition, the change is mainly associated with decreased ApoA. Uses: Cytochrome p-450 cyp3a inducers. Synonyms: CI-1011; CI 1011; CI1011; ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl este; Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl esterr. Grade: >98%. CAS No. 166518-60-1. Molecular formula: C29H43NO4S. Mole weight: 501.72.
Avasimibe. Group: Biochemicals. Alternative Names: CI 1011; PD 148515; N-[2-[2, 4, 6-tris (1-methylethyl) phenyl]acetyl]-2-sulfamic Acid 6-Bis(1-methylethyl)phenyl Ester. Grades: Highly Purified. CAS No. 166518-60-1. Pack Sizes: 25mg. Molecular Formula: C29H43NO4S, Molecular Weight: 501.72. US Biological Life Sciences.
Worldwide
Avasimibe
Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 μM for ACAT1 and ACAT2, respectively[1]. Avasimibe can be used for the research of prostate cancer[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-1011; PD-148515. CAS No. 166518-60-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13215.
Avasopasem manganese
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O 2 *- to hydrogen peroxide (H 2 O 2 ), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GC-4419; M-40419. CAS No. 435327-40-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109110.
Avatrombopag
Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501; E5501; YM477. CAS No. 570406-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463.
Avatrombopag
Avatrombopag is an orally available platelet thrombopoietin receptor (TPOR; MPL) agonist, with potential megakaryopoiesis stimulating activity. Upon administration, avatrombopag binds to and stimulates TPOR, which may lead to the proliferation and differentiation of megakaryocytes from bone marrow progenitor cells. This increases the production of platelets and may prevent chemotherapy-induced thrombocytopenia (CIT). TPOR is a cytokine receptor and member of the hematopoietin receptor superfamily. Alternative Names: AKR-501. Doptelet. E5501. CAS No. 570406-98-3. Product ID: API570406983. Molecular formula: C29H34Cl2N6O3S2. Mole weight: 649.7. SMILES: C1CCC(CC1)N2CCN(CC2)C3=C(N=C(S3)NC(=O)C4=CC(=C(N=C4)N5CCC(CC5)C(=O)O)Cl)C6=CC(=CS6)Cl. Appearance: white solid powder. Category: Platelet-Promoting APIs.
Avatrombopag
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Synonyms: AKR-501; AKR 501; AKR501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542. Grade: 98%. CAS No. 570406-98-3. Molecular formula: C29H34Cl2N6O3S2. Mole weight: 649.65.
Avatrombopag hydrochloride
Avatrombopag hydrochloride is a novel thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia. Synonyms: Avatrombopag (hydrochloride). Grade: 98%. CAS No. 570403-17-7. Molecular formula: C29H35Cl3N6O3S2. Mole weight: 686.12.
Avatrombopag hydrochloride
Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride. CAS No. 570403-17-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463B.
Avatrombopag Impurity 28
Avatrombopag Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-cyclohexylpiperazine-1-carboxylate. CAS No. 1224935-95-8. Molecular formula: C15H28N2O2. Mole weight: 268.4. Catalog: APB1224935958.
Avatrombopag Impurity 31
Avatrombopag Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 123971-45-9. Molecular formula: C7H5ClN2S2. Mole weight: 216.71. Catalog: APB123971459.
Avatrombopag Impurity 82
Avatrombopag Impurity 82. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(5-bromo-4-chlorothiophen-2-yl)thiazol-2-amine. CAS No. 1534575-19-3. Molecular formula: C7H4BrClN2S2. Mole weight: 293.87. Catalog: APB1534575193.
Avatrombopag maleate
Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. CAS No. 677007-74-8. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7.
Avatrombopag maleate
Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 maleate; E5501 maleate; YM477 maleate. CAS No. 677007-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463A.
AvBD10
AvBD10 is an antimicrobial peptide produced by liver, Peking duck, Anas platyrhynchos (Domestic duck). It has antibacterial activity against Gram-positive bacteria and Gram-negative bacteria. Synonyms: Duck AvBD10; Duck avian beta defensin 10; Val-Leu-Leu-Phe-Leu-Phe-Gln-Ala-Ala-Pro-Gly-Ser-Ala-Asp-Ala-Pro-Phe-Ala-Asp-Thr-Ala-Ala-Cys-Arg-Ser-Gln-Gly-Asn-Phe-Cys-Arg-Ala-Gly-Ala-Cys-Pro-Pro-Thr-Phe-Ala-Ala-Ser-Gly-Ser-Cys-His-Gly-Gly-Leu-Leu-Asn-Cys-Cys-Ala-Lys. Grade: >98%.
AVB-S6-500
AVB-S6-500 is a GAS6-AXL signaling pathway blocker with high affnity for GAS6. AVB-S6-500 is developed for the treatment of cancer and nonmalignant fibrotic conditions as a drug candidate. It is in a phase I clinical trial for its safety and tolerability study. Uses: Potential treatment of cancer and nonmalignant fibrotic conditions. Synonyms: Aravive-S6.
Avdoralimab
Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450.
AVE-0118
AVE 0118 is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to the anti-AF property of AVE0118. Synonyms: [1,1'-Biphenyl]-2-carboxamide, 2'-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide; AVE 0118; AVE0118. Grade: ≥95%. CAS No. 498577-53-0. Molecular formula: C30H29N3O3. Mole weight: 479.57.
AVE 0118 hydrochloride
AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effect on ventricular repolarization. Noteworthy, the atrial selective and dose-dependent prolongation of atrial refractoriness (ERP) by AVE 0118 has been claimed to be an inhibitory effect of sodium channel activity in an atrial-selective manner, and may therefore contribute to anti-AF property of AVE0118. Synonyms: Benzeneacetamide, 4-methoxy-N-[[2'-[[[2-(3-pyridinyl)ethyl]amino]carbonyl][1,1'-biphenyl]-2-yl]methyl]-, hydrochloride (1:1); 2'-[[[2-(4-Methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl][1,1'-biphenyl]-2-carboxamide hydrochloride; [1,1'-Biphenyl]-2-carboxamide, 2'-[[[(4-methoxyphenyl)acetyl]amino]methyl]-N-[2-(3-pyridinyl)ethyl]-, hydrochloride; 2'-[[2-(4-Methoxyphenyl)acetylamino]methyl]biphenyl-2-carboxylic acid (2-pyridin-3-yl-ethyl)amide hydrochloride; AVE 0118 hydrochloride; AVE0118 hydrochloride. Grade: 99%. CAS No. 2108821-80-1. Molecular formula: C30H29N3O3.HCl. Mole weight: 516.03.
AVE 0991
AVE 0991 is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: 1-ethyl-3-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea5-formyl-4-methoxy-2-phenyl-1-((4-(2-ethyl-aminocarbonylsulfonamido-5-isobutyl-3-thienyl)phenyl)methyl)imidiazoleAVE 0991; AVE-0991; AVE0991. CAS No. 304462-19-9. Molecular formula: C29H32N4O5S2. Mole weight: 580.72.
AVE 0991
AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304462-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15778.
AVE 0991 sodium salt
AVE 0991 sodium salt, is an agonist of nonpeptide Ang-(1-7) receptor Mas that has potential as a cardiovascular drug. Synonyms: AVE-0991 sodium salt; AVE 0991 sodium salt; AVE0991 sodium salt; sodium; ethylcarbamoyl-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylazanideAVE 0991 (sodium salt)306288-04-0C29H31N4NaO5S23195AH. CAS No. 306288-04-0. Molecular formula: C29H31N4NaO5S2. Mole weight: 602.70.
Ave-1625
Ave-1625. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AVE-1625;Drinabant. Product Category: Heterocyclic Organic Compound. Appearance: A crystalline solid. CAS No. 358970-97-5. Molecular formula: C23H20Cl2F2N2O2S. Mole weight: 497.38. Density: 1.458. Product ID: ACM358970975. Alfa Chemistry ISO 9001:2015 Certified. Categories: AVE 1625.
AVE-8063
AVE-8063 is an antimitotic agent or microtubule inhibitor with potential anticancer activity. Synonyms: AVE8063; AVE 8063; (Z)-1-(3-Amino-4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene; (Z)-2-methoxy-5-(3,4,5-trimethoxystyryl) aniline. Grade: >98%. CAS No. 162705-07-9. Molecular formula: C18H21NO4. Mole weight: 315.37.
AVE-8134
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively. Synonyms: AVE8134; 2-Methyl-6-((3-((2-phenyloxazol-4-yl)methoxy)propoxy)methyl)benzoic acid. CAS No. 304025-09-0. Molecular formula: C22H23NO5. Mole weight: 381.42.
Avelumab
Avelumab is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730.
Avelumab (anti-PD-L1)
Avelumab (anti-PD-L1) is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108730A.
Avenaciolide
It is produced by the strain of Aspergillus avenaceus. A bicyclic bis-butyrolactone; isolated from aspergillus avenaceu; an antifungal agent; inhibits glutamate transport; an atypical ionophore. Synonyms: Avenaciolid; Furo(3,4-b)furan-2,6(3H,4H)-dione, dihydro-3-methylene-4-octyl- (VAN) (8CI). Grade: >95% by HPLC. CAS No. 20223-76-1. Molecular formula: C15H22O4. Mole weight: 266.33.
avenacosidase
Isolated from oat (Avena sativa) seedlings. The product acts as a defense system against fungal infection. Also acts on avenacoside A. Group: Enzymes. Synonyms: As-P60. Enzyme Commission Number: EC 3.2.1.188. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3872; avenacosidase; EC 3.2.1.188; As-P60. Cat No: EXWM-3872.
Avenanthramide A
Avenanthramide A is a phytoalexin, which can be found in oats ( Avena sativa L. ). Avenanthramide A targets the RNA helicase DDX3 , leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active [1]. Uses: Scientific research. Group: Natural products. CAS No. 108605-70-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114977.
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 116764-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-124344.
Avenanthramide-c methyl ester
Avenanthramide-c methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Avenanthramide-C methyl ester, 955382-52-2, AGN-PC-00DGLK, CTK8E8646, methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate. Product Category: Heterocyclic Organic Compound. CAS No. 955382-52-2. Molecular formula: C17H15NO6. Mole weight: 329.304100 [g/mol]. Purity: 0.96. IUPACName: methyl 2-[3-(3,4-dihydroxyphenyl)prop-2-enoylamino]-5-hydroxybenzoate. Product ID: ACM955382522. Alfa Chemistry ISO 9001:2015 Certified.
Avenanthramide-C methyl ester
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 = 40 μM). Synonyms: Avenanthramide-C methyl ester; 955382-52-2; methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate; SCHEMBL20963041; IUZHCICFVDHVMC-XVNBXDOJSA-N; AKOS040755114; Methyl (E)-2-(3-(3,4-dihydroxyphenyl)acrylamido)-5-hydroxybenzoate; 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxy-benzoic acid, methyl ester; 2-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]5-hydroxybenzoic acid, methyl ester. Grade: ≥90%. CAS No. 955382-52-2. Molecular formula: C17H15NO6. Mole weight: 329.3.
Avenanthramide D
Avenanthramide D is a multifaceted bioactive compound with antioxidant, anti-inflammatory and cardiovascular protective effects used in studying diabetes, cancer and cardiovascular disorders. Synonyms: Avenanthramide 1p; Dianthramide P; N-p-Coumarylanthranilic acid; N-(E)-p-Coumaroylanthranilic acid. CAS No. 115610-36-1. Molecular formula: C16H13NO4. Mole weight: 283.28.
Averantin
Averantin is an anthraquinone fungal metabolite produced by Aspergillus sp. associated with Panax notoginseng. It is a mycotoxic intermediate in the pathway to aflatoxin B1. It displays antifungal activity against Fusariumsolani (pathogenic fungus of P. notoginseng) with minimum inhibitory concentrations of 16-32 ug/mL. It also shows antibacterial activity against Bacillus subtilis with minimum inhibitory concentrations of 16-32 ug/mL. Synonyms: 1,3,6,8-Tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-9,10-anthracenedione; (-)-Averantin; (S)-1,3,6,8-Tetrahydroxy-2-(1-hydroxyhexyl)-9,10-anthracenedione; 9,10-Anthracenedione, 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxyhexyl]-; (1'S)-averantin; (S)-(-)-averantin; (S)-averantin. Grade: ≥95%. CAS No. 5803-62-3. Molecular formula: C20H20O7. Mole weight: 372.37.
Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 5803-62-3. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Worldwide
averantin hydroxylase
A heme-thiolate (P-450) monooxygenase isolated from Aspergillus parasiticus. There is no reaction with (1'R)-averantin. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Enzyme Commission Number: EC 1.14.13.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0772; averantin hydroxylase; EC 1.14.13.174; AVN hydroxylase; avnA (gene name); (1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating). Cat No: EXWM-0772.
Avermectin A1a
Avermectin A1a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: SCHEMBL1681257. CAS No. 65195-51-9. Molecular formula: C49H74O14. Mole weight: 887.10.
Avermectin A2a
Avermectin A2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a had the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22,23-dihydroabamectin B1a (above 80%) and 22,23 dioxabamectin B1b(below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Avermectin A1a; SCHEMBL1681224. CAS No. 50914-15-3. Molecular formula: C49H76O15. Mole weight: 905.12.
Avermectin B1
Avermectin B1. Group: Biochemicals. Grades: Highly Purified. CAS No. 71751-41-2. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C49H74O14. US Biological Life Sciences.
Worldwide
Avermectin B1a
It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Synonyms: Ivermectin EP Impurity A; Abamectin B1a; Doramectin Impurity 3. Grade: ≥95%. CAS No. 65195-55-3. Molecular formula: C48H72O14. Mole weight: 873.08.
Avermectin B1a
Avermectin B1a. Group: Biochemicals. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C48H72O14. US Biological Life Sciences.
Worldwide
Avermectin B1a
Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abamectin B1a. CAS No. 65195-55-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15308.
Avermectin B1a (5-O-Demethylavermectin A1a, Antibiotic C 076B1a)
Avermectin B1a is the major component (>80%) of the commerically available anthelmintic Abamectin (R) used to control parasitic nematodes in livestock. Avermectin B1a contains a secbutyl residue in the 24-position. In vitro and in vivo studies have shown this analogue is the more potent analogue in the commerical product. Group: Biochemicals. Alternative Names: 5-O-Demethylavermectin A1a, Antibiotic C 076B1a. Grades: Highly Purified. CAS No. 65195-55-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Avermectin B1a aglycone
It is an acid degradation product produced by hydrolysis of the disaccharide unit of avermectin. It is an inhibitor of nematode larval development. It has no paralytic activity. It is an anthelmintic in animal health. Synonyms: (6R,13S,25R)-22,23-didehydro-5-O-demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B. Grade: >95% by HPLC. CAS No. 71828-14-3. Molecular formula: C34H48O8. Mole weight: 584.74.
Avermectin b1a ≥95% (HPLC)
Avermectin b1a ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 2.5g. US Biological Life Sciences.
Worldwide
Avermectin B1a monosaccharide
It is an acid degradation product produced by selective hydrolysis of the terminal saccharide unit of avermectin. It is a potent inhibitor of nematode larval development. It has no paralytic activity. Synonyms: 4'-O-de(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-5-O-demethyl-avermectin A1a; 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a; MSB 1a. Grade: >95% by HPLC. CAS No. 71831-09-9. Molecular formula: C41H60O11. Mole weight: 728.91.
Avermectin B1b
Avermectin B1b is the minor component of the commercially available anthelmintic marketed as Abamectin. It is used broadly against nematodes, ticks, flies, and ants. Synonyms: Ivermectin EP Impurity B; 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-avermectin A1a; Doramectin Impurity 2. Grade: ≥95%. CAS No. 65195-56-4. Molecular formula: C47H70O14. Mole weight: 859.05.
Avermectin B1b (Antibiotic C 076B1b)
Avermectin B1b is the minor component (<20%) of the commerically available anthelmintic marketed as Abamectin(R) used to control parasitic nematodes in livestock. Avermectin B1b contains a isopropyl residue in the 24-position. In vitro and in vivo studies have shown this analogue to be active but less potent than the B1a analogue. Group: Biochemicals. Alternative Names: Antibiotic C 076B1b. Grades: Highly Purified. CAS No. 65195-56-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Avermectin B2a
Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Synonyms: Ivermectin EP Impurity C; (23S)-5-O-demethyl-23-hydroxy-22,23-dihydro-avermectin A1a. CAS No. 65195-57-5. Molecular formula: C48H74O15. Mole weight: 891.09.
avermitilol synthase
Requires Mg2+. The recombinent enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol. The (1S)-hydrogen of farnesyl diphosphate is retained. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5260; avermitilol synthase; EC 4.2.3.96. Cat No: EXWM-5260.
Averufin
Averufin is produced by the strain of Asergillus sp. Ames tests showed a weak mutagenic effect. Synonyms: Averufine; 3,4,5,6-Tetrahydro-7,9,11-trihydroxy-2-methyl-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione. CAS No. 14016-29-6. Molecular formula: C20H16O7. Mole weight: 368.34.
a-Vi-5
a-Vi-5. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A-VI-5;Bradykinin potentiating factor alpha-vi-5. Product Category: Heterocyclic Organic Compound. CAS No. 39194-96-2. Molecular formula: C22H40N6O10. Mole weight: 548.59. Purity: 0.96. IUPACName: 6-amino-2-[[2-[[2-[[2-[(2-amino-3-methylbutanoyl)amino]-5-hydroxy-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]hexanoic acid. Canonical SMILES: CC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)O)N. Density: 1.34g/cm³. Product ID: ACM39194962. Alfa Chemistry ISO 9001:2015 Certified. Categories: A-Vi-Pel.
Avian Eggshell Membrane Collagen
Avian Eggshell Membrane Collagen.
CA, FL & NJ
Avibactam
Avibactam is a novel investigational non-beta-lactam beta-lactamase inhibitor that is being developed for possible use in combination with ceftaroline in the U.S. Avibactam does not have any intrinsic antibacterial activity in its own right, but appears to be capable of inhibiting beta-lactamase enzymes that belong to molecular classes A and C.Avibactam is useful for Antibiotics. Uses: Beta-lactamase inhibitors. Synonyms: Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester; Avibactam free acid; [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate. Grade: >98%. CAS No. 1192500-31-4. Molecular formula: C7H11N3O6S. Mole weight: 265.24.
Avibactam free acid
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104 free acid. CAS No. 1192500-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14879.
Avibactam Impurity 11
Avibactam Impurity 11 is an impurity of Avibactam. Synonyms: Avibactam Impurity 11; 1416134-60-5; Ethyl 5-phenylmethoxyiminopiperidine-2-carboxylate; Avibactam Impurity 15; (S,E)-ethyl 5-((benzyloxy)imino)piperidine-2-carboxylate. Grade: > 95%. CAS No. 1416134-60-5. Molecular formula: C14H18N2O3. Mole weight: 262.31.
Avibactam Impurity 27
Avibactam Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,5R)-ethyl 5-((benzyloxy)amino)piperidine-2-carboxylate oxalate. CAS No. 1416134-48-9. Molecular formula: C17H24N2O7. Mole weight: 368.38. Catalog: APB1416134489.
Avibactam Impurity 3
Avibactam Impurity 3 is an impurity of Avibactam. Synonyms: (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxamide; 2-Piperidinecarboxamide, 5-[(phenylmethoxy)amino]-, (2S,5R)-; (2S,5R)-5-(benzyloxyamino)-piperidine-2-carboxylic acid amide; 5R-(5-Benzyloxyamino) L-Pipecolic Amide. Grade: > 95%. CAS No. 1416134-49-0. Molecular formula: C13H19N3O2. Mole weight: 249.32.