A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Avobenzone | Oil-soluble UVA filter. Ability to absorb ultraviolet light over a wider range of wavelengths than many other sunscreen agents. Absorption maximum of 357 nm. Uses: Sun care products, baby sun care products, daily sun protection, decorative cosmetics. Additional or Alternative Names: Butyl methoxydibenzoylmethane. Product Category: Heterocyclic Organic Compound. Appearance: Off-white to yellowish, crystalline powder, weak odor. CAS No. 70356-09-1. Molecular formula: C20H22O3. Mole weight: 310.4. Purity: 97-104%. Density: 1.079. Product ID: ACM70356091. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Avobenzone | analytical standard. Group: Uv blockers. |  |
| Avocado Extract | Avocado Extract. Applications: Used for health care products, dietary supplements, herb medicine and cosmetic industry. Group: Others. Synonyms: Avocado Extract; Persea americana L. Purity: 30% Total Phytosterol by UV. Appearance: Yellow Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Persea americana L. Avocado Extract; Persea americana L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-122. |  |
| Avocado Oil | Avocado Oil. CAS No. 8024-32-6. VIGON Item # 507697. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers, Cosmetics. |  America & Internationally |
| Avocado Powder | Avocado powder takes avocado as raw material, adopts spray drying technology, low temperature physical grinding technology, instant grinding, to obtain edible high quality avocado powder. Product ID: CDF4-0226. Category: Flavour. Product Keywords: Flavor Enhancers; Avocado Powder; CDF4-0226; Flavour;. Grade: Food Grade. Color: White powder. Physical State: powder. Storage: Room Temperature. Applications: It is widely used in processing various avocado flavored foods and added to various nutritional foods. |  |
| Avoralstat | Avoralstat (BCX4161), a potent and orally active plasma kallikrein (PKK) inhibitor, is used for hereditary angioedema research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCX4161. CAS No. 918407-35-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16735. |  |
| Avoralstat | Avoralstat, also known as BCX-4161, is an oral plasma kallikrein (PKK) inhibitor and Bradykinin inhibitor, used to treat hereditary angioedema. Synonyms: BCX-4161; BCX 4161; BCX4161. CAS No. 918407-35-9. Molecular formula: C28H27N5O5. Mole weight: 513.54. |  |
| Avosentan | Avosentan, also known as SPP301, R-639, and RO 67-0565, is a potent and selective endothelin receptor(ETA receptor) antagonist. Synonyms: N-[6-methoxy-5-(2-methoxyphenoxy)-2-pyridin-4-ylpyrimidin-4-yl]-5-methylpyridine-2-sulfonamide; Avosentan; 290815-26-8; UNII-L94KSX715K; SPP301; SPP301; SPP301; RO 67-0565; RO-67-0565; RO67-0565; R-639; Avosentan. Grade: 95%. CAS No. 290815-26-8. Molecular formula: C23H21N5O5S. Mole weight: 479.51. | |
| Avosentan | Avosentan is a competitive antagonist of Endothelin-1 (ET-1) with a high selectivity for the ETA receptor. Avosentan may be a potential option in the treatment of glaucoma. Group: Biochemicals. Alternative Names: N-[6-Methoxy-5-(2-methoxyphenoxy)-2-(4-pyridinyl)-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 67-0565; SPP 301. Grades: Highly Purified. CAS No. 290815-26-8. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Avotaciclib | Avotaciclib is a potent and orally active CDK1 inhibitor that can be studied in locally advanced or metastatic pancreatic cancer. Synonyms: BEY1107; 3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)-. CAS No. 1983983-41-0. Molecular formula: C13H11N7O. Mole weight: 281.27. | |
| Avotaciclib | Avotaciclib (BEY1107) is an orally active cyclin-dependent kinase 1 (CDK1) inhibitor. Avotaciclib can inhibit the proliferation and induce apoptosis of tumor cells. Avotaciclib can be used in the research of cancer such as pancreatic cancer and lung cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BEY1107. CAS No. 1983983-41-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137432. | |
| Avotaciclib trihydrochloride | Avotaciclib trihydrochloride is a potent and orally active CDK1 inhibitor that can be studied in locally advanced or metastatic pancreatic cancer. Synonyms: BEY1107 trihydrochloride; 3-Pyridinol, 2,6-bis(2-amino-4-pyrimidinyl)-, hydrochloride (1:3). CAS No. 1983984-01-5. Molecular formula: C13H11N7O.3HCl. Mole weight: 390.66. | |
| Avrainvillamide | Avrainvillamide is a fungal metabolite and monomeric form of stephacidin B that has been found in A. ochraceus. It is active against S. aureus, S. pyogenes, and E. faecalis (MICs = 12.5, 12.5, and 25 μg/ml, respectively). Avrainvillamide inhibits the growth of LNCaP, BT-549, T47D, and MALME-3M cancer cells with GI50 values of 0.24, 0.62, 0.21, and 0.41 μM, respectively. Synonyms: CJ-17,665; CJ17,665; CJ 17,665; 3,11,12,13,13aS,14-hexahydro-3,3,14,14-tetramethyl-8H,10H-7aS,12aS-(iminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazole-8,16-dione 15-oxide. Grade: >95% by HPLC. CAS No. 269741-97-1. Molecular formula: C26H27N3O4. Mole weight: 445.52. | |
| Avridine | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Avridine | Avridine is a potent synthetic non-immunogenic adjuvant that used to induce arthritis in Lewis (LEW) and DA rats. Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Synonyms: CP 20961; CP20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane. Grade: ≥98%. CAS No. 35607-20-6. Molecular formula: C43H90N2O2. Mole weight: 667.19. | |
| Avridine | A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing. Group: Biochemicals. Alternative Names: 2, 2'- [ [3- (Dioctadecylamino) propyl] imino] bisethanol; CP 20961; CP-20961; N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane; N, N-Dioctadecyl-N', N'-bis (2-hydroxyethyl) propanediamine. Grades: Highly Purified. CAS No. 35607-20-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Avutometinib | Avutometinib (Ro 5126766) is a first-in-class dual MEK / RAF inhibitor that allosterically inhibits BRAF V600E , CRAF , MEK , and BRAF (IC 50 : 8.2, 56, 160 nM, and 190 nM, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 5126766; CH5126766. CAS No. 946128-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18652. | |
| AVX 13616 | AVX 13616 shows the potent in vivo antibacterial activity of Avexa's lead antibacterial candidate, particularly against drug-resistant Staphylococcus pathogens. It was as active as mupirocin in a nasal decolonization model but required only a single application. It showed broad spectrum antibacterial activity against a range of isolates with MICs of 2-4 micrograms per millilitre against S. aureus, coagulase negative staphylococci, enterococci, MRSA, VISA and VRSA. Synonyms: AVX-13616; AVX 13616; AVX13616. Grade: >98%. CAS No. 900814-48-4. Molecular formula: C50H73Cl2N7O7. Mole weight: 955.06. | |
| Avycaz | Avycaz is a fixed-dose combination medication composed of ceftazidime, a cephalosporin antibiotic, and avibactam, a β-lactamase inhibitor. Synonyms: ceftazidime & avibactam; ceftazidime + avibactam; Avibactam / Ceftazidime. CAS No. 1393723-27-7. Molecular formula: C29H33N9O13S3. Mole weight: 811.8. | |
| Awamycin | Awamycin is produced by the strain of Streptomyces sp. No. 80-217. It has anti-gram-positive bacteria and antitumor activity. Synonyms: Antibiotic Tan 528A; Protostreptovaricin I, 10,25-didemethyl-21-hydroxy-10-(methoxycarbonyl)-19-O-methyl-25-(methylthio)-; Protostreptovaricin-31-oic acid, 25-demethyl-21-hydroxy-19-O-methyl-2S-(methylthio)-, methyl ester. Molecular formula: C38H49NO12S. Mole weight: 743.86. | |
| AWD 12-281 | AWD 12-281 is a strong selective phosphodiesterase 4 (PDE4) inhibitor which has potent effects in models of lung inflammation using inhalative administration. Synonyms: N-(3,5-dichloropyridin-4-yl)-2-[1-[(4-fluorophenyl)methyl]-5-hydroxyindol-3-yl]-2-oxoacetamide; AWD 12-281; AWD12-281; AWD-12-281; UNII-550671J24D; GSK 842470; GSK 842470; GSK-842470. Grade: >98%. CAS No. 257892-33-4. Molecular formula: C22H14Cl2FN3O3. Mole weight: 458.27. | |
| AWD 131-138 | AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy. Synonyms: AWD 131-138; AWD-131-138; AWD131-138; AWD 131138; Imepitoin; 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one. CAS No. 188116-07-6. Molecular formula: C13H14ClN3O2. Mole weight: 279.724. | |
| AWL-II-38.3 | AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf[1][2][1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1135205-94-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18832. | |
| AX-024 | AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ~1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-?, IFN-?, IL-10 and IL-17A. Uses: Scientific research. Group: Signaling pathways. CAS No. 1370544-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107390. | |
| AX-024 | AX-024 is a first-in-class and orally available TCR-Nck interaction inhibitor that selectively inhibits TCR-triggered T cell activation with an IC50 of ~1 nM. It regulates cell signaling by targeting SH3 domains. It strongly inhibits the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A. Synonyms: 1-[[4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]pyrrolidine; Pyrrolidine, 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-. Grade: ≥98%. CAS No. 1370544-73-2. Molecular formula: C21H22FNO2. Mole weight: 339.40. | |
| AX-024 hydrochloride | AX-024 hydrochloride is an inhibitor of T cell receptor (TCR) that selectively inhibits the TCR-Nck interaction. By modulating TCR signaling, AX-024 prevents the development of psoriasis and asthma and, furthermore, exerts a long-lasting therapeutic effect in a model of autoimmune encephalomyelitis. Synonyms: 1-[[4-(4-Fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]pyrrolidine hydrochloride; Pyrrolidine, 1-[[4-(4-fluorophenyl)-6-methoxy-2H-1-benzopyran-3-yl]methyl]-, hydrochloride (1:1). Grade: 99%. CAS No. 1704801-24-0. Molecular formula: C21H22FNO2.HCl. Mole weight: 375.86. | |
| AX 048 | Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate (AX 048) is a PLA2 (Phospholipase A2) and PGE2 (Prostaglandin E2) inhibitor. PLA2 is known as calcium-dependent cytosolic PLA2 (cPLA2), which selectively releases arachidonic acid from membrane phospholipids. It plays a central role in initiating the synthesis of prostaglandins and leukotrienes. This compound also contains a specific affinity for group IVA cPLA2 which moderates antihyperalgesia effects. Synonyms: AX-048; AX 048; Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester; UNII-8782Z45DLV; 8782Z45DLV; Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester; ethyl 4-(2-oxohexadecanoylamino)butanoate; ethyl 4-(2-oxohexadecanamido)butanoate; CHEMBL574723; SCHEMBL4781039; DTXSID60236282; AKOS040755666; ethyl 4-[(2-oxohexadecanoyl)amino] butanoate; Q27269809; 4- [(1, 2- dioxohexadecyl)amino]- butanoic acid, ethyl ester. Grade: ≥98%. CAS No. 873079-69-7. Molecular formula: C22H41NO4. Mole weight: 383.6. | |
| AX-15836 | AX-15836 is a highly potent and selective ERK5 inhibitor (IC50 = 8 nM) with >1,000-fold selectivity for ERK5 over a panel of over 200 kinases. Synonyms: 2-[2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5-methyl-11-methylsulfonylpyrimido[4,5-b][1,4]benzodiazepin-6-one; AKOS030210962; ZINC669678933; AX15836; AX 15836; AX-15836. CAS No. 2035509-96-5. Molecular formula: C32H40N8O5S. Mole weight: 648.78. | |
| AX-15836 | AX-15836 is a potent and selective ERK5 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2035509-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101846. | |
| AX20017 | AX20017 is a highly selective PknG inhibitor. It acts by blocking the proliferation of M. tuberculosis. AX20017 is shown to completely inactivate PknG-mediated blockage of lysosomal transfer and degradation of M. bovis BCG in macrophages at concentrations (10μM or higher) that does not otherwise affect the growth of BCG outside its infected host. Synonyms: AX 20017; AX-20017; PknG Inhibitor; 2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide. Grade: ≥98% (HPLC). CAS No. 329221-38-7. Molecular formula: C13H16N2O2S. Mole weight: 264.35. | |
| Axatilimab | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SNDX-6352. CAS No. 2155851-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99452. | |
| AXC-715 | AXC-715 is a dual agonist of TLR7/TLR8. Synonyms: 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-; 4-Amino-2-butyl-1H-imidazo[4,5-c]quinoline-1-butanamine; 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine; AXC 715; AXC715. Grade: ≥95%. CAS No. 313350-31-1. Molecular formula: C18H25N5. Mole weight: 311.43. | |
| AXC-715 hydrochloride | AXC-715 hydrochloride is a dual agonist of TLR7/TLR8. (Extracted from patent WO2020168017 A1). Synonyms: 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride; 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-, hydrochloride (1:1). Grade: ≥90%. CAS No. 2490497-93-1. Molecular formula: C18H26ClN5. Mole weight: 347.89. | |
| AXC-715 trihydrochloride | AXC-715 trihydrochloride is a dual agonist of TLR7/TLR8. (Extracted from patent WO2020168017 A1). Synonyms: 1-(4-Aminobutyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine Trihydrochloride; 1H-Imidazo[4,5-c]quinoline-1-butanamine, 4-amino-2-butyl-, hydrochloride (1:3). Grade: 95%. CAS No. 2479276-17-8. Molecular formula: C18H28Cl3N5. Mole weight: 420.81. | |
| Axenomycin B | Axenomycin B is produced by the strain of Streptomyces lisandri F. I. 2604. It has antifungal, nematode and trichomonas activities. Molecular formula: C29H38O10. Mole weight: 546.60. | |
| Axinysone A | Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Synonyms: (-)-Axinysone A. Grade: 97.5%. CAS No. 1114491-57-4. Molecular formula: C15H22O2. Mole weight: 234.338. | |
| Axinysone B | Axinysone B is a metabolite of the mushroom Anthracophyllum sp. BCC18695. Synonyms: (-)-Axinysone B; 2H-Cyclopropa[a]naphthalen-2-one, 1,1a,4,5,6,7,7a,7b-octahydro-4-hydroxy-1,1,7,7a-tetramethyl-, (1aS,4R,7S,7aS,7bR)-. Grade: 98.0%. CAS No. 1114491-60-9. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Axitinib | Axitinib is a multi-targeted tyrosine kinase inhibitor with IC 50 s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1 , VEGFR2 , VEGFR3 and PDGFRβ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-013736. CAS No. 319460-85-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10065. | |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Synonyms: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. Grade: ≥98%. CAS No. 319460-85-0. Molecular formula: C22H18N4OS. Mole weight: 386.5. | |
| Axitinib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Axitinib | Axitinib. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Highly Purified. CAS No. 319460-85-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C22H18N4OS. US Biological Life Sciences. | Worldwide |
| Axitinib-[13C,d3] | Axitinib-[13C,d3] is a labelled Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: [13C,2H3]-N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; (E)-N-(methyl-13C-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Grade: > 98%. CAS No. 1261432-00-1. Molecular formula: C21[13C]H15D3N4OS. Mole weight: 390.48. | |
| Axitinib-d3 | Labeled analogue of Axitinib, a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. Group: Biochemicals. Alternative Names: N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Axitinib-[d3] | Axitinib-[d3] is the labelled analogue of Axitinib. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Synonyms: Axitinib D3; N-(Methyl-d3)-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736-d3; Axitinib-d3 (N-methyl-d3). Grade: 95% by HPLC; 98% atom D. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. | |
| Axitinib-D3 (Axitinib Impurity 36) | Axitinib-D3 (Axitinib Impurity 36). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1126623-89-9. Molecular formula: C22H15D3N4OS. Mole weight: 389.49. Catalog: APB1126623899. | |
| Axitinib Impurity 1 | Axitinib Impurity 1 is an impurity of Axitinib, a drug primarily used in the treatment of advanced renal cell carcinoma and metastatic thyroid cancer. Synonyms: Axitinib Impurity c. Grade: > 95%. CAS No. 885126-40-9. Molecular formula: C22H18N4OS. Mole weight: 386.48. | |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). Grade: > 95%. CAS No. 1428728-83-9. Molecular formula: C44H36N8O2S2. Mole weight: 772.96. | |
| Axitinib Impurity 6 | Axitinib Impurity 6 is an impurity arising from the depths of Axitinib - an oral tyrosine kinase inhibitor profoundly employed in the therapy against advanced renal carcinoma. Synonyms: Axitinib Impurity d. Grade: > 95%. CAS No. 1443118-72-6. Molecular formula: C29H25N5OS. Mole weight: 491.62. | |
| Axitinib Impurity 8 | Axitinib Impurity 8 is an impurity of axitinib fortifying the therapy against the perilous adversity known as advanced renal carcinoma. Synonyms: 2-(1H-indazol-6-ylthio)-N-Methyl- BenzaMide; BenzaMide, 2-(1H-indazol-6-ylthio)-N-Methyl-; Axitinib Impurity e. Grade: > 95%. CAS No. 944835-85-2. Molecular formula: C15H13N3OS. Mole weight: 283.35. | |
| Axitinib Impurity C | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2-((1H-Indazol-6-yl)sulfinyl)-N-methylbenzamide; Axitinib EP Impurity C; Axitinib Impurity 56. Grade: ≥95%. CAS No. 1959572-97-4. Molecular formula: C15H13N3O2S. Mole weight: 299.35. | |
| Axitinib Impurity D | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: 2-[(1-Acetyl-1H-indazol-6-yl)sulfinyl]-N-methylbenzamide; Axitinib EP Impurity D. Grade: ≥95%. CAS No. 1959572-98-5. Molecular formula: C17H15N3O3S. Mole weight: 341.38. | |
| Axitinib N-oxide | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: (E)-N-Methyl-2-[[3-[2-(1-oxido-2-pyridinyl)ethenyl]-2H-indazol-6-yl]thio]benzamide. Grade: ≥95%. Molecular formula: C22H18N4O2S. Mole weight: 402.47. | |
| Axitinib sulfone | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: Sulfonyl axitinib; (E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylsulfonyl)benzamide; N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfonyl]benzamide. Grade: ≥95%. CAS No. 1348536-59-3. Molecular formula: C22H18N4O3S. Mole weight: 418.47. | |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Synonyms: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide; Axitinib Impurity A. Grade: > 95%. CAS No. 1347304-18-0. Molecular formula: C22H18N4O2S. Mole weight: 402.48. | |
| AXKO-0046 | AXKO-0046, indole derivative, is an uncompetitive Lactate dehydrogenase B (LDHB) selective inhibitor.AXKO-0046 has LDHB inhibitory activity with an EC50 value of 42 nM.AXKO-0046 can be used for the research of cancer metabolism[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-147216. | |
| AXL (473-end), active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Axl active human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Axltide | Axltide is based on mouse insulin receptor substrate 1 (amino acids 979-989). It is also a substrate for the kinases AXL, DDR2, MST1 and JAK2. Synonyms: Axl/Insulin Receptor Substrate Peptide; H-Lys-Lys-Ser-Arg-Gly-Asp-Tyr-Met-Thr-Met-Gln-Ile-Gly-OH; L-lysyl-L-lysyl-L-seryl-L-arginyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-methionyl-L-threonyl-L-methionyl-L-glutaminyl-L-isoleucyl-glycine. Grade: ≥98%. CAS No. 143364-95-8. Molecular formula: C63H107N19O20S2. Mole weight: 1514.77. | |
| AY 9944 | Cholesterol synthesis inhibitor; inhibits both 7-dehydrocholesterol ?7-reductase and ?8,7-sterol isomerase. A sonic hedgehog inhibitor. Group: Biochemicals. Alternative Names: trans-N1, N4-Bis [ (2-chlorophenyl) methyl ] -1, 4-cyclohexane dimethanamine Hydrochloride; N, N'-Bis (o-chlorobenzyl)-trans-1, 4-cyclohexanebis (methylamine) Dihydrochloride. Grades: Highly Purified. CAS No. 366-93-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AY 9944 | AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol ?7-reductase (DHCR7) enzyme with an IC50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol ?7-?8 isomerase, which causes the accumulation of cholest-8-en-3?-ol[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 366-93-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107420. | |
| AY 9944 dihydrochloride | AY 9944 dihydrochloride is the dihydrochloride salt of AY 9944, which is an amphiphilic and cell-permeable diamine and acts as a sonic hedgehog inhibitor. It may induce a rapid and irreversible reduction in acidic-sphingomyelinase activity in fibroblasts. It is also a potent inhibitor of cholesterol biosynthesis and esterification, and shows teratogenic properties. It inhibits Δ7-dehydrocholesterol reductase and cholesterol esterificatio, thus reduces cholesterol biosynthesis. It blocks the cellular response to Hh proteins. It is important in Sonic Hedgehog signaling and teratogenicity studies. Synonyms: AY-9944; AY 9944; AY9944; trans-N1,N4-Bis[(2-chlorophenyl)methyl]-1,4-cyclohexanedimethanamine Hydrochloride; N,N'-Bis(o-chlorobenzyl)-trans-1,4-cyclohexanebis(methylamine) Dihydrochloride; trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedimethanamine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 366-93-8. Molecular formula: C22H30Cl4N2. Mole weight: 464.30. | |
| AY 9944 dihydrochloride | AY 9944 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 366-93-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ayanin | Ayanin isolated from the rhizomes of Curcuma aromatica. Synonyms: QUERCETIN 3,7,4'-TRIMETHYL ETHER; AYANIN; 2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one; 3',5-Dihydroxy-3,4',7-trimethoxyflavone; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one. Grade: 0.985. CAS No. 572-32-7. Molecular formula: C18H16O7. Mole weight: 344.3. | |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Synonyms: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grade: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79. | |
| AY-NH2 | AY-NH2. Group: Biochemicals. Grades: Purified. CAS No. 352017-71-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AZ0108 | AZ0108 is an orally bioavailable, PARP1,2,6 inhibitor that causes a multi-polar spindle phenotype at double digit nM concentrations. AZ0108 has been utilized as in vitro tools and in vivo probes to investigate the biological consequences of inhibiting centrosome clustering through PARP enzymes. Synonyms: (S)-4-((3-(3-(1,1-difluoroethyl)-6-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-7-carbonyl)phenyl)difluoromethyl)phthalazin-1(2H)-one; AZ0108; AZ-0108; AZ 0108. Grade: >98%. CAS No. 1825345-52-5. Molecular formula: C24H20F4N6O2. Mole weight: 500.45. | |
| AZ084 | AZ084 is a potent, selective, allosteric and orally active CCR8 antagonist with a Ki of 0.9 nM. It has the potential to treat asthma. Synonyms: Methanone, (5-amino-2-pyridinyl)[9-[(2,3-dihydro-2,2-dimethyl-4-benzofuranyl)methyl]-3,9-diazaspiro[5.5]undec-3-yl]-; (5-Amino-2-pyridinyl){9-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undec-3-yl}methanone. Grade: ≥97%. CAS No. 929300-19-6. Molecular formula: C26H34N4O2. Mole weight: 434.57. | |
| AZ 10397767 | AZ 10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). It significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models and slows growing tumors. It attenuates oxaliplatin-induced NF-κB activation and increases oxaliplatin cytotoxicity, thus potentiates oxaliplatin-induced apoptosis in AIPC cells. It may be potential for treating cystic fibrosis and chronic obstructive pulmonary disease. It is orally bioavailable. Synonyms: AZ-10397767; AZ 10397767; AZ10397767. 5-[[(3-Chloro-2-fluorophenyl)methyl]thio]-7-[[(1R)-2-hydroxy-1-methylethyl]amino]thiazolo[4,5-d]pyrimidin-2(3H)-one. Grade: ≥98% by HPLC. CAS No. 333742-63-5. Molecular formula: C15H14ClFN4O2S2. Mole weight: 400.88. | |
| AZ 10417808 | AZ 10417808 is a non-peptide and selective inhibitor of human caspase-3 with Ki value of 247 nM. It is selective over other caspases. It blocks cellular and biochemical features of apoptosis in cells. It also blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells. It is a bioactive chemical. Synonyms: AZ10417808; AZ-10417808; AZ 10417808; 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide; AQZ-1. Grade: ≥98% by HPLC. CAS No. 331645-84-2. Molecular formula: C18H13Cl2N5O4. Mole weight: 434.23. | |
| AZ 10606120 dihydrochloride | AZ 10606120 dihydrochloride is the dihydrochloride salt of AZ 10606120, which is a potent and negative allosteric modulator of the human P2X7 receptor. Its KD values are 1.4 and 19 nM at human and rat P2X7 receptors respectively. It binds in a positive cooperative manner to sites and acts as a negative allosteric modulator. It is a key modulator of the PI3K/GSK3β/VEGF signaling network. It inhibits tumor growth and shows antiangiogenic effects in mice. Synonyms: AZ10606120; AZ 10606120; AZ-10606120; N-[2-[[2-[(2-Hydroxyethyl)amino]ethyl]amino]-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide Dihydrochloride; 2-(1-Adamantyl)-N-[2-[[2-[(2-hydroxyethyl)amino]ethyl]amino]quinolin-5-yl]acetamide Dihydrochloride. Grade: ≥98% by HPLC. CAS No. 607378-18-7. Molecular formula: C25H36N4O2Cl2. Mole weight: 495.48. | |
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