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| Product | Description | |
|---|---|---|
| Bleomycin | Bleomycin. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3S,4S,5R,6R)-2-(((2R,3S,4S,5S,6S)-2-((1R,2S)-2-(6-amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-(((2R,3S,4S)-5-(((2S,3R)-1-((2-(4-((3-((4-aminobutyl)amino)propyl)carbamoyl)-[2,4'-bithiazol]-2'-yl)ethyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-4-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl carbamate. Molecular Formula: C57H89N19O21S2. Mole Weight: 1440.56. Catalog: APB03866. |  |
| Bleomycin a2 | Heterocyclic Organic Compound. Alternative Names: BLEOMYCIN A2;Bleomycinamide, N1-[3-(dimethylsulfonio)propyl]-; BLEMOYCIN AZ; Bleogin; N1-[3- (Dimethylsulfonio) propyl]bleomycinamide; Pingyangmycin A2;Zhengguangmycin A2;Einecs 234-356-5. CAS No. 11116-31-7. Molecular formula: C55H84N17O21S3+. Mole weight: 1415.55. Catalog: ACM11116317. |  |
| Bleomycin A2 | It is one of two components found in the glycopeptide antineoplastic antibiotic Bleomycin sulfate. Bleomycin sulfate is a chemotherapeutic agent used for the treatment of hodgkins lymphoma. It is isolated from the bacterium Streptomyces verticillus. Synonyms: Bleomycin a2; Bleomycinamide, N1-[3-(dimethylsulfonio)propyl]-; Bleogin; N1-[3- (Dimethylsulfonio) propyl]bleomycinamide; Pingyangmycin A2; Zhengguangmycin A2. Grades: ≥95.0%. CAS No. 11116-31-7. Molecular formula: C55H84N17O21S3. Mole weight: 1415.55. |  |
| Bleomycin a5 | Heterocyclic Organic Compound. Alternative Names: Bleomycinamide, N1-[3-[(4-aminobutyl)amino]propyl]-; bleomycetin; Bleomycin A5; N1- (3- ( (4-Aminobutyl) amino) propyl) bleomycinamide; Pingyangmycin A5;Zhengguanmycin A5;Nsc350895. CAS No. 11116-32-8. Molecular formula: C57H89N19O21S2. Mole weight: 1440.56. Density: 1.56g/cm³. Catalog: ACM11116328. | |
| Bleomycin A5 hydrochloride | Bleomycin A5 hydrochloride is an antitumor antibiotic which induces apoptosis. Synonyms: Bleomycin A5 HCl; N1- (3- ( (4-Aminobutyl) amino) propyl) bleomycinamide hydrochloride; Bleomycinamide, N(sup 1)-(3-((4-aminobutyl)amino)propyl)-, hydrochloride. CAS No. 55658-47-4. Molecular formula: C57H89CuN19O21S2.3HCl. Mole weight: 1477.02. | |
| Bleomycin A5 Hydrochloride | Bleomycin A5 Hydrochloride. Group: Biochemicals. Alternative Names: N1- [3- [ (4-Aminobutyl) amino] propyl] bleomycinamide Hydrochloride. Grades: Highly Purified. CAS No. 55658-47-4. Pack Sizes: 5mg. Molecular Formula: C57H90ClN19O21S2, Molecular Weight: 1477.02. US Biological Life Sciences. |  Worldwide |
| Bleomycin A6 | Bleomycin is a glycopeptide anti-tumor antibiotic produced by Streptomyces verticillus B-80-Z2. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity, and is particularly active against Mycobacterium phlei. Synonyms: zhengguangmycin A6. CAS No. 37293-17-7. Molecular formula: C60H96N20O21S2. Mole weight: 1497.65. | |
| Bleomycin B4 | Bleomycin B4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R, 3S, 4S, 5R, 6R) -2- ( ( (2R, 3S, 4S, 5S, 6S) -2- ( (1R, 2S) -2- (6-amino-2- ( (S) -3-amino-1- ( ( (S) -2, 3-diamino-3-oxopropyl) amino) -3-oxopropyl) -5-methylpyrimidine-4-carboxamido) -3- ( ( (2R, 3S, 4S) -5- ( ( (2S, 3R) -1- ( (2- (4- ( (4- (3- (4-guanidinobutyl) guanidino) butyl) carbamoyl) -[2, 4'-bithiazol]-2'-yl) ethyl) amino) -3-hydroxy-1-oxobutan-2-yl) amino) -3-hydroxy-4-methyl-5-oxopentan-2-yl) amino) -1- (1H-imidazol-4-yl) -3-oxopropoxy) -4, 5-dihydroxy-6- (hydroxymethyl) tetrahydro-2H-pyran-3-yl) oxy) -3, 5-dihydroxy-6- (hydroxymethyl) tetrahydro-2H-pyran-4-yl carbamate. CAS No. 9060-11-1. Molecular Formula: C60H95N23O21S2. Mole Weight: 1538.67. Catalog: APB9060111. | |
| Bleomycin complex (as sulfate salts) | Bleomycin is a complex of 11 glycopeptide antitumor antibiotics originally isolated from Streptomyces verticillus in 1972. The dominant components of the complex are bleomycin A2 and B2 and typically represent >90% of the total weight with the remainder comprising the minor analogues. Bleomycins have found clinical application in the treatment of a range of tumors. Bleomycins act by intercalation of DNA and RNA. In the presence of oxygen and metal ions, notably copper and iron, bleomycins form a pseudo- enzyme that induces DNA cleavage. Group: Biochemicals. Alternative Names: Blenoxane; Blexane; Bleo. Grades: Highly Purified. CAS No. 9041-93-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bleomycin EP impurity B | Bleomycin EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 11116-32-8. Molecular Formula: C57H89N19O21S2. Mole Weight: 1440.57. Catalog: APB11116328. | |
| Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67763-87-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17565A. |  |
| Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic. Group: Inhibitors. Alternative Names: Bleomycin, hydrochloride. CAS No. 67763-87-5. Molecular formula: C50H71N16O21S2R?x(HCl). Mole weight: Unspecified. Appearance: Solid. Purity: 0.9945. Canonical SMILES: O=C (C1=NC ([C@H] (CC (N)=O)NC[C@H] (N)C (N)=O)=NC (N)=C1C)N[C@H] (C (N[C@H] (C)[C@@H] (O)[C@H] (C)C (N[C@] ([C@H] (O)C) ([H])C (NCCC2=NC (C3=NC (C (N[R])=O)=CS3)=CS2)=O)=O)=O)[C@H] (C4=CN=CN4)O[C@H]5[C@H] ([C@H] ([C@@H] ([C@@H] (O5)CO)O)O)O[C@]6 ([H])[C@H] ([C@H] ([C@@H] ([C@H] (O6)CO)O)OC (N)=O)O. NC (NCCCC[R])=N. [R]CCC[S+] (C)C. [H]Cl. [R=]. [Bleomycin A2].[R=].[Bleomycin B2]. Catalog: ACM67763875. | |
| bleomycin hydrolase | The molecule is a homohexamer in which the monomers have a papain-like tertiary structure (in peptidase family C1). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain. Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity. Known from bacteria as well as eukaryotic organisms. Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyses Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates. Group: Enzymes. Synonyms: aminopeptidase C (Lactococcus lactis). Enzyme Commission Number: EC 3.4.22.40. CAS No. 53096-17-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4215; bleomycin hydrolase; EC 3.4.22.40; 53096-17-6; aminopeptidase C (Lactococcus lactis). Cat No: EXWM-4215. |  |
| Bleomycin impurity 2 | Bleomycin impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C55H83N16O22S3+. Mole Weight: 1416.54. Catalog: APB10385. | |
| Bleomycin impurity 4 | Bleomycin impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2'-((3S,6R,7S,8S,11S)-1-(6-amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((R)-(((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4'-bithiazole]-4-carboxylic acid. CAS No. 37364-66-2. Molecular Formula: C50H72N16O22S2. Mole Weight: 1313.33. Catalog: APB37364662. | |
| Bleomycin Impurity 7 Sulfate | Bleomycin Impurity 7 Sulfate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 9041-93-4 (unspecified sulfate content); N-[3- (dimethylsulfonio) propyl]bleomycinamide (bleomycin A2) and N-[4- (carbamimidoylamino) butyl]bleomycinamide (bleomycin B2), sulfate (1:1). Molecular Formula: C55H34N20O21S2· H2SO4. Mole Weight: 1513.62. Catalog: APB03864. | |
| Bleomycin Impurity 8 | Bleomycin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3-(2'-((3S,6R,7S,8S,11S)-1-(6-amino-2-((S)-3-amino-1-(((S)-3-amino-3-oxo-2-(propan-2-ylideneamino)propyl)amino)-3-oxopropyl)-5-methylpyrimidin-4-yl)-3-((R)-(((2R,3S,4S,5S,6S)-3-(((2R,3S,4S,5R,6R)-4-(carbamoyloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)(1H-imidazol-4-yl)methyl)-7-hydroxy-11-((R)-1-hydroxyethyl)-6,8-dimethyl-1,4,9,12-tetraoxo-2,5,10,13-tetraazapentadecan-15-yl)-[2,4'-bithiazole]-4-carboxamido)propyl)dimethylsulfonium. Molecular Formula: C58H88N17O21S3. Mole Weight: 1455.62. Catalog: APB03865. | |
| Bleomycin impurity A5 HCl | Bleomycin impurity A5 HCl. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 11116-32-8 (free salt); (2R,3S,4S,5R,6R)-2-(((2R,3S,4S,5S,6S)-2-((1R,2S)-2-(6-amino-2-((S)-3-amino-1-(((S)-2,3-diamino-3-oxopropyl)amino)-3-oxopropyl)-5-methylpyrimidine-4-carboxamido)-3-(((2R,3S,4S)-5-(((2S,3R)-1-((2-(4-((3-((4-aminobutyl)amino)propyl)carbamoyl)-[2,4'-bithiazol]-2'-yl)ethyl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl)amino)-1-(1H-imidazol-4-yl)-3-oxopropoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl carbamate hydrochloride. CAS No. 55658-47-4. Molecular Formula: C57H89N19O21S2·HCl. Mole Weight: 1477.03. Catalog: APB55658474. | |
| Bleomycin sulfate | Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Bleomycin sulfate. CAS No. 9041-93-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17565. | |
| Bleomycin sulfate | Bleomycin Sulfate is part of a group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic. Group: Inhibitors. Alternative Names: Blenmycins;BleoMycin Sufate;BLEMOYCIN SULFATE;Bleomycin (sulfate);BLENOXANE. CAS No. 9041-93-4. Molecular formula: C110H168N34O46S7. Appearance: White powder. Purity: 0.9853. Canonical SMILES: O=C (C1=NC ([C@H] (CC (N)=O)NC[C@H] (N)C (N)=O)=NC (N)=C1C)N[C@H] (C (N[C@H] (C)[C@@H] (O)[C@H] (C)C (N[C@] ([C@H] (O)C) ([H])C (NCCC2=NC (C3=NC (C (N[R])=O)=CS3)=CS2)=O)=O)=O)[C@H] (C4=CN=CN4)O[C@H]5[C@H] ([C@H] ([C@@H] ([C@@H] (O5)CO)O)O)O[C@]6 ([H])[C@H] ([C@H] ([C@@H] ([C@H] (O6)CO)O)OC (N)=O)O. NC (NCCCC[R])=N. [R]CCC[S+] (C)C. O=S (O) (O)=O. [R=]. [Bleomycin A2].[R=].[Bleomycin B2]. Catalog: ACM9041934. | |
| Bleomycin Sulfate | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: N/A. CAS No. 9041-93-4. Prepack ID 25097489-10mg. See USA prepack pricing. |  |
| Bleomycin Sulfate (A2, B2) | A group of related glycopeptide antibiotics. Bleomycin A2 is the main component of the bleomycin employed clinically. Antineoplastic. Mixture of Bleomycin A2, B2 isolated from Streptomyces verticillus. Group: Biochemicals. Alternative Names: Blenoxane; Blexane; Bleo. Grades: Purified. CAS No. 9041-93-4. Pack Sizes: 10mg, 50mg. Molecular Formula: C55H84N17O21S3·xH2SO4, Molecular Weight: 1415.56 (free acid basis). US Biological Life Sciences. | Worldwide |
| Bleselumab | Bleselumab (ASKP 1240) is a human anti- CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity ( K d : 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASKP 1240; Anti-Human CD40 Recombinant Antibody. CAS No. 1453067-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99257. | |
| Blestriarene C | Phenols. CAS No. 120090-81-5. Molecular formula: C30H22O6. Mole weight: 478.5. Appearance: Powder. Purity: 0.98. IUPACName: 1-(2,7-dihydroxy-4-methoxyphenanthren-1-yl)-4-methoxyphenanthrene-2,7-diol. Canonical SMILES: COC1=C2C3=C (C=CC2=C (C (=C1)O)C4=C5C=CC6=C (C5=C (C=C4O)OC)C=CC (=C6)O)C=C (C=C3)O. Catalog: ACM120090815. | |
| Bletilla Extract | Bletilla Extract. Applications: Use for stop bleeding by astringency, relieving swelling and promoting tissue regeneration. treat haematenesis and tomachache; and with dondey-hide gelatin, dried rehmannia root, biota tops.treat diabrotic skin sorebe. Group: Others. Synonyms: Bletilla Extract; Bletilla striata (Thunb.ex A.Murray)Rchb.f. Purity: 10:1 by TLC. Appearance: Brown yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Root. Species: Bletilla striata (Thunb.ex A.Murray)Rchb.f. Bletilla Extract; Bletilla striata (Thunb.ex A.Murray)Rchb.f.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-196. | |
| Bleximenib | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib shows antiproliferative activity and induces apoptosis. Bleximenib has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617; Menin-MLL inhibitor 24. CAS No. 2654081-35-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148669. | |
| Bleximenib oxalate | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) oxalate is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib oxalate shows antiproliferative activity and induces apoptosis. Bleximenib oxalate has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617 oxalate; Menin-MLL inhibitor 24 oxalate. CAS No. 2866179-95-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148669A. | |
| b-L-Fucopyranosylamine | b-L-Fucopyranosylamine is an indispensable compound, used for studying a myriad of ailments, encompassing cancer and autoimmune disorders. Deemed exceptional due to its distinctive attributes, this compound showcases immense efficacy in selectively studying aberrant cell proliferation, while concurrently modulating the intricate immune response. Synonyms: 2-amino-6-methyloxane-3,4,5-triol; B-l-fucopyranosylamine; 103419-79-0; SCHEMBL22779020; AKOS030241001; FT-0668893. CAS No. 103419-79-0. Molecular formula: C6H13NO4. Mole weight: 163.17. | |
| b-L-Fucopyranosyl nitromethane | b-L-Fucopyranosyl nitromethane is a paramount biomedical compound, standing as a resolute weapon to study a diverse spectrum of afflictions encompassing malignancy and inflammatory disorders. Synonyms: 2,6-Anhydro-1,7-dideoxy-7-nitro-D-glycero-D-galacto-heptitol. Molecular formula: C7H13NO6. Mole weight: 207.2. | |
| b-L-Glucose-1-phosphate ammonium salt | b-L-Glucose-1-phosphate ammonium salt is an indispensable compound fundamental to the research of diverse disorders pertaining to glucose metabolism, encompassing glycogen storage diseases and diabetes. By serving as a synthetic predecessor, it facilitates the compoundion of glucose-1-phosphate is an imperatively significant molecule intricately entwined with glycogen research and development and subsequent energy storage. Molecular formula: C6H19N2O9P. Mole weight: 294.20. | |
| BLI 489 Hydrate | BLI-489 is a penem β-lactamase inhibitor, which has shown activity against class A, C, and D β-lactamases. BLI-489 is being tested in combination therapy for drug-resistant bacteria. Group: Biochemicals. Alternative Names: (5R,6Z)-6-[(5,6-Dihydro-8H-imidazo[2,1-c][1,4]oxazin-2-yl)methylene]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Sodium Salt Hydrate; WAY-185489. Grades: Purified. CAS No. 623564-40-9. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??N?NaO?S; xH?O, Molecular Weight: 327.29. US Biological Life Sciences. | Worldwide |
| blinatumomab | Blinatumomab is a monoclonal antibody used for the treatment of Philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. It effects against tumor cells via binding to a CD3 site for T cells and a CD19 site for the target B cells, which express both in pediatric and adult populations. Uses: The treatment of philadelphia chromosome-negative relapsed or refractory acute lymphoblastic leukemia. Synonyms: Blincyto. CAS No. 853426-35-4. Molecular formula: C2367H3577N649O772S19. Mole weight: 54100. | |
| Blinatumomab | Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anatumomab. CAS No. 853426-35-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P9963. | |
| Blinin | Blinin is a diterpene originally isolated from C. blini. Uses: Antimalarial. Synonyms: 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone; 2(5H)-Furanone, 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-; 4-[2-[(1S,2R,4aS,7S,8aR)-4a-[(Acetyloxy)methyl]-1,2,3,4,4a,7,8,8a-octahydro-7-hydroxy-5-(hydroxymethyl)-1,2-dimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone. Grades: >98%. CAS No. 125675-09-4. Molecular formula: C22H32O6. Mole weight: 392.49. | |
| Bliretrigine | Bliretrigine is a sodium channel blocker. Bliretrigine has the effect of relieving pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233229-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145558. | |
| BLM Helicase Inhibitor, ML216 (ML-216, 1- (4-Fluoro-3- (trifluoromethyl) phenyl) -3- (5- (pyridin-4-yl) -1, 3, 4-thiadiazol-2-yl) urea) | A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50 = 2.98 and 0.97uM, respectively). Competes with and reversibly blocks DNA binding to BLM. However, the inhibition appears to be non-competitive with respect to ATP. Exhibits anti-proliferative activity in cells expressing BLM, but not in those lacking BLM. Induces sister chromatid exchanges (SCEs) and enhances the sensitivity of BLM containing PSNF5 cells to aphidicolin without affecting PSNG13 cells that are devoid of BLM. Displays favorable microsomal (T1/2 > 1.2h) and plasma stability (~100% at 5h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H?F?N?OS. US Biological Life Sciences. | Worldwide |
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| Blonanserin | A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic. Synonyms: 2-(4-ethylpiperazin-1-yl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Grades: 0.99. CAS No. 132810-10-7. Molecular formula: C23H30FN3. Mole weight: 367.512. | |
| Blonanserin | Blonanserin (AD-5423) is a potent and orally active 5-HT 2A ( K i =0.812 nM) and dopamine D2 receptor ( K i =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD-5423. CAS No. 132810-10-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13575. | |
| Blonanserin | A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic. Group: Biochemicals. Alternative Names: 2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine; Lonasen; AD 5423. Grades: Highly Purified. CAS No. 132810-10-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Blonanserin-d5 | Blonanserin-d5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1346599-86-7. Molecular Formula: C23H25D5FN3. Mole Weight: 372.54. Catalog: APB1346599867. | |
| Blonanserin Impurity 1 | Blonanserin Impurity 1 is an impurity of blonanserin pharmaceutical formulations. Blonanserin is an atypical antipsychotic medication used in the therapy of schizophrenia and other related mental disorders. Synonyms: Cycloocta[b]pyridine, 2-(4-ethyl-1-piperazinyl)-4-[4-(4-ethyl-1-piperazinyl)phenyl]-5,6,7,8,9,10-hexahydro-. Grades: > 95%. CAS No. 1648791-23-4. Molecular formula: C29H43N5. Mole weight: 461.70. | |
| Blonanserin Impurity 10 | Blonanserin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H30FN3O2. Mole Weight: 399.51. Catalog: APB06860. | |
| Blonanserin Impurity 11 | Blonanserin Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H30FN3O2. Mole Weight: 399.51. Catalog: APB06861. | |
| Blonanserin Impurity 13 | Blonanserin Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H31N3O. Mole Weight: 365.52. Catalog: APB06862. | |
| Blonanserin Impurity 14 | Blonanserin Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-14-0. Molecular Formula: C17H17ClFN. Mole Weight: 289.78. Catalog: APB132813140. | |
| Blonanserin Impurity 15 | Blonanserin Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143213-96-1. Molecular Formula: C17H17ClFNO. Mole Weight: 305.78. Catalog: APB143213961. | |
| Blonanserin Impurity 16 | Blonanserin Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-4-(2-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Molecular Formula: C17H17ClFN. Mole Weight: 289.77. Catalog: APB03164. | |
| Blonanserin Impurity 17 | Blonanserin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-4-(3-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Molecular Formula: C17H17ClFN. Mole Weight: 289.77. Catalog: APB03166. | |
| Blonanserin Impurity 17 | Blonanserin Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 49860-76-6. Molecular Formula: C7H16N2. Mole Weight: 128.22. Catalog: APB49860766. | |
| Blonanserin Impurity 18 | Blonanserin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-4-phenyl-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Molecular Formula: C17H18ClN. Mole Weight: 271.78. Catalog: APB03163. | |
| Blonanserin Impurity 18 | Blonanserin Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1477480-40-2. Molecular Formula: C19H24FN3. Mole Weight: 313.42. Catalog: APB1477480402. | |
| Blonanserin Impurity 19 | Blonanserin Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-chloro-4-(4-methoxyphenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Molecular Formula: C18H20ClNO. Mole Weight: 301.81. Catalog: APB03162. | |
| Blonanserin Impurity 19 | Blonanserin Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1477480-42-4. Molecular Formula: C19H21FN2O2. Mole Weight: 328.39. Catalog: APB1477480424. | |
| Blonanserin Impurity 2 | Blonanserin Impurity 2 is an impurity of blonanserin used in the therapy of various mental disorders, including schizophrenia and bipolar disorder. Blonanserin acts as a potent antagonist at dopamine D2 and serotonin 5-HT2 receptors, effectively treating symptoms associated with these conditions. Synonyms: Cycloocta[b]pyridine, 2-(4-ethyl-1-piperazinyl)-5,6,7,8,9,10-hexahydro-4-phenyl-. Grades: > 95%. CAS No. 132810-75-4. Molecular formula: C23H31N3. Mole weight: 349.52. | |
| Blonanserin Impurity 20 | Blonanserin Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C23H30FN3O. Mole Weight: 383.51. Catalog: APB06863. | |
| Blonanserin Impurity 21 | Blonanserin Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(4-ethylpiperazin-1-yl)-4-(4-methoxyphenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. CAS No. 132810-93-6. Molecular Formula: C24H33N3O. Mole Weight: 379.54. Catalog: APB132810936. | |
| Blonanserin Impurity 21 | Blonanserin Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 848301-82-6. Molecular Formula: C23H30FN3O. Mole Weight: 383.51. Catalog: APB848301826. | |
| Blonanserin Impurity 22 | Blonanserin Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-fluorophenyl)-N-methyl-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2-amine. Molecular Formula: C18H21FN2. Mole Weight: 284.37. Catalog: APB03161. | |
| Blonanserin Impurity 23 | Blonanserin Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 848301-76-8. Molecular Formula: C23H30FN3O. Mole Weight: 383.51. Catalog: APB848301768. | |
| Blonanserin Impurity 24 | Blonanserin Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H26FN3O. Mole Weight: 355.46. Catalog: APB06864. | |
| Blonanserin Impurity 26 | Blonanserin Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-22-0. Molecular Formula: C17H17Cl2N. Mole Weight: 306.23. Catalog: APB132813220. | |
| Blonanserin Impurity 27 | Blonanserin Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-16-2. Molecular Formula: C17H17ClFN. Mole Weight: 289.78. Catalog: APB132813162. | |
| Blonanserin Impurity 28 | Blonanserin Impurity 28. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-15-1. Molecular Formula: C17H17ClFN. Mole Weight: 289.78. Catalog: APB132813151. | |
| Blonanserin Impurity 29 | Blonanserin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-13-9. Molecular Formula: C17H18ClN. Mole Weight: 271.79. Catalog: APB132813139. | |
| Blonanserin Impurity 3 | Blonanserin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H19FN2. Mole Weight: 270.35. Catalog: APB06856. | |
| Blonanserin Impurity 30 | Blonanserin Impurity 30. Uses: For analytical and research use. Group: Impurity standards. CAS No. 132813-20-8. Molecular Formula: C18H20ClNO. Mole Weight: 301.81. Catalog: APB132813208. | |
| Blonanserin Impurity 31 | Blonanserin Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H10F2N2O. Mole Weight: 308.29. Catalog: APB06865. | |
| Blonanserin Impurity 32 | Blonanserin Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C18H9ClF2N2. Mole Weight: 326.73. Catalog: APB06866. | |
| Blonanserin Impurity 33 | Blonanserin Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H20N2O3. Mole Weight: 252.31. Catalog: APB06867. | |
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