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| Product | Description | |
|---|---|---|
| Butyrophenone | Butyrophenone is used as an antipsychotic drug in pharmacotherapy. Group: Biochemicals. Alternative Names: 1-Phenyl-1-butanone; 1-Benzoylpropane; 1-Phenyl-1-butanone; Butanophenone; NSC 8463; Phenyl n-Propyl Ketone; Phenyl Propyl Ketone; Propyl Phenyl Ketone; n-Butyrophenone; n-Propyl Phenyl Ketone. Grades: Highly Purified. CAS No. 495-40-9. Pack Sizes: 5g. US Biological Life Sciences. |  Worldwide |
| Butyrophenone, -alpha--amino--alpha--methyl- (1CI) | Butyrophenone, -alpha--amino--alpha--methyl- (1CI). CAS No. 861597-75-3. Product ID: ACM861597753. Molecular formula: C11H15NO. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Butyrospermol | Butyrospermol is a natural product[1]. Uses: Scientific research. Category: Natural products. CAS No. 472-28-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124045. |  |
| Butyrylcarnitine | Butyrylcarnitine is an endogenous metabolite found in plasma. Elevated levels of Butyrylcarnitine are closely associated with abnormalities in lipid and energy metabolism. Butyrylcarnitine can serve as a diagnostic and prognostic indicator for certain diseases, such as heart failure and head and neck cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25576-40-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113168. | |
| Butyryl Chloride | Butyryl Chloride. Group: Biochemicals. Alternative Names: Butyryl Chloride; Butanoic Acid Chloride; Butyric Acid Chloride; Butyric Chloride; Butyroyl Chloride; n-Butanoyl Chloride; n-Butyroyl Chloride; n-Butyryl Chloride. Grades: Highly Purified. CAS No. 141-75-3. Pack Sizes: 5g. Molecular Formula: C4H7ClO, Molecular Weight: 106.55. US Biological Life Sciences. | Worldwide |
| BUTYRYLCHOLINE BROMIDE | BUTYRYLCHOLINE BROMIDE. Alternative Names: BUTYRYLCHOLINE BROMIDE;trimethyl[2-(1-oxobutoxy)ethyl]ammonium bromide. CAS No. 18956-84-8. Product ID: ACM18956848. Molecular formula: C9H20BrNO2. Mole weight: 254.16. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Butyrylcholine chloride | 25g Pack Size. Group: Building Blocks, Organics. Formula: C9H20ClNO2. CAS No. 2963-78-2. Prepack ID 49629139-25g. Molecular Weight 209.71. See USA prepack pricing. |  |
| Butyrylcholine Chloride | Butyrylcholine Chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 2963-78-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Butyryl coenzyme A lithium salt | Butyryl coenzyme A lithium salt. Grade: 95%. CAS No. 102282-28-0. Molecular formula: C25H39Li3N7O17P3S. Mole weight: 855.423. |  |
| Butyryl-Coenzyme A sodium | Butyryl-Coenzyme A (Butyryl CoA) sodium is a coenzyme A-containing derivative of Butyric acid. Butyryl-Coenzyme A sodium is responsible for the final step of Butyrate production in bacteria[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Butyryl CoA sodium. CAS No. 125527-24-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-138177. | |
| Butyryl-[d7] Chloride | Butyryl-[d7] Chloride is the labelled analogue of Butyryl Chloride, which is used in the synthesis of chromones and also used in the synthesis of antiproliferative agents based on anilines. Synonyms: Butyryl-d7 Chloride; Butanoyl-2,2,3,3,4,4,4-d7 chloride; Butanoic Acid-d7 Chloride; Butyric Acid-d7 Chloride; Butyroyl-d7 Chloride; n-Butanoyl-d7 Chloride; n-Butyroyl-d7 Chloride; n-Butyryl-d7 Chloride. Grade: ≥98%; ≥98% atom D. CAS No. 1219805-71-6. Molecular formula: C4D7ClO. Mole weight: 113.59. | |
| Butyryl-L-carnitine chloride | (R)-Butyryl Carnitine is a potential prodrug of Carnitine, via the carnitine transporter OCTN2 and the amino acid transporter ATB0,+. It is an inhibitor of intestinal transporters, which block carnitine uptake by the carnitine transporter with IC50s of 1.5 μM and glycine transport with IC50s of 4.6 μM in in human retinal pigment epithelial (HRPE) cells. Butyryl-L-carnitine is used for treating seizure disorders. Synonyms: L-Butyrylcarnitine; C4 Carnitine. Grade: ≥95%. CAS No. 162067-50-7. Molecular formula: C11H22NO4·Cl. Mole weight: 267.8. | |
| Butyryl-L-carnitine chloride 98+% (TLC) | Butyryl-L-carnitine chloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Butyryl-L-carnitine chloride-[d3] | Butyryl-L-carnitine chloride-[d3] is the deuterium labelled edition of Butyryl-L-carnitine chloride. (R)-Butyryl Carnitine is a potential prodrug of Carnitine, via the carnitine transporter OCTN2 and the amino acid transporter ATB0+. It is an inhibitor of intestinal transporters, which blocks carnitine uptake by the carnitine transporter with IC50s of 1.5 μM and glycine transport with IC50s of 4.6 μM in human retinal pigment epithelial (HRPE) cells. Butyryl-L-carnitine is used for treating seizure disorders. Synonyms: Butyryl-L-carnitine-(N-methyl-d3) hydrochloride. Grade: 98% (CP); 99% atom D. CAS No. 1334532-21-6. Molecular formula: C11H19D3ClNO4. Mole weight: 270.77. | |
| Butyryl Phosphate Dilithium Salt | Butyryl phosphate has a role in metabolism. Group: Biochemicals. Alternative Names: Butanoic Acid Phosphono Ester Dilithium Salt; Butanoyl Phosphate Dilithium Salt. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Butyrylthiocholine chloride | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials, Organics. Formula: C9H20ClNOS. CAS No. 22026-63-7. Prepack ID 26608039-1g. Molecular Weight 225.78. See USA prepack pricing. | |
| Butyrylthiocholine iodide | 5g Pack Size. Group: Building Blocks, Organics. Formula: C9H20INOS. CAS No. 1866-16-6. Prepack ID 34904481-5g. Molecular Weight 317.23. See USA prepack pricing. | |
| Butyzamide | Butyzamide is a non-peptidyl thrombopoietin receptor, activator of Mpl. It also augments the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. It has potential for treatment of thrombocytopenia. Group: Inhibitors. CAS No. 1110767-45-7. Pack Sizes: 1mg. Product ID: E1352. Formula: C29H32Cl2N2O5S. |  United States; Europe |
| Butyzamide | Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of platelets in mouse xenotransplantation assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1110767-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148748. | |
| BV02 | BV02 is a 14-3-3 inhibitor and an antibacterial agent. BV02 enhances the cleavage of PARP and caspase-3. BV02 induces Apoptosis, Autophagy, and enhances Akt activation. BV02 has anti-B. melitensis infection and epilepsy-promoting effects. BV02 can also be used in colitis research. Uses: Scientific research. Category: Signaling pathways. CAS No. 292870-53-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101985. | |
| BV6 | BV-6 is a selective inhibitor of apoptosis (IAP) family with IC50 value of 7.2 μM when tested with H460 cells. It acts by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. BV-6 induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 μM. In BALB/c mice model with transplanted abdominal cavities from donor mouse uterine tissue, intraperitoneally with BV-6 repressed the advancement of endometriosis, cell proliferative activity via inhibiting the expression of IAPs. In hematological THP-1 cells, pre-treatment with BV-6 increased the CIK cells killing ability and the same results were achieved in solid malignancy RH30 cells. Grade: ≥98%. CAS No. 1001600-56-1. Molecular formula: C70H96N10O8. Mole weight: 1205.57. | |
| BV6 | BV6 is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. BV6 shows an IC50 of 7.2 μM in MTS assays in HCC193 cells. BV6 can be used in the research of endometrial cancer and endometriosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1001600-56-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16701. | |
| BV6 | BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor. Group: Inhibitors. CAS No. 1001600-56-1(freebase). Pack Sizes: 5mg. Product ID: S7597. Formula: C70H96N10O8.xCF3COOH. Smiles: CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC(C(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)NCCCCCCNC(=O)C(C(C5=CC=CC=C5)C6=CC=CC=C6)NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Bvacado Oil microencapsulated powder | Bvacado Oil microencapsulated powder. Product ID: CDF4-0212. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0212; Bvacado Oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: Bvacado. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc. |  |
| BVD 10 | BVD 10 is a selective NPY Y1 receptor antagonist (Ki = 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors, respectively) with no activity at Y4 receptors. Synonyms: BVD 10; BVD10; BVD-10. Grade: >98%. CAS No. 262418-00-8. Molecular formula: C58H92N16O13. Mole weight: 1221.46. | |
| Bvdv-IN-1 | BVDV-IN-1, a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV) (EC50 = 1.8 μM), has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC). It directly binds to a hydrophobic pocket of the BVDV RNA-dependent RNA polymerase (RdRp), and inhibits the replication of TSC-resistant BVDV variants in vitro. Synonyms: BVDV-IN-1; 345651-04-9; 2-[4-(2-phenylquinazolin-4-yl)piperazin-1-yl]ethanol; 2-(4-(2-Phenylquinazolin-4-yl)piperazin-1-yl)ethanol; EX-A5593; AKOS000915262; MS-25053; HY-131976; CS-0145660; G13690. Grade: ≥98%. CAS No. 345651-04-9. Molecular formula: C20H22N4O. Mole weight: 334.41. | |
| BVT.13 | BVT.13 is an orally active and selective PPARγ agonist with a maximal efficacy similar to that of Rosiglitazone (HY-17386). In addition, BVT.13 exhibits antidiabetic activity in ob/ob mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 756813-87-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114853. | |
| BVT-14225 | BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93. | |
| BVT-14225 | BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 376638-65-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18055. | |
| BVT173187 | BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374984-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117971. | |
| BVT 2733 | BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grade: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95. | |
| BVT 2733 hydrochloride | BVT 2733 hydrochloride is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1. Synonyms: BVT 2733 hydrochloride; BVT2733 hydrochloride; BVT-2733 hydrochloride; 3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide hydrochloride. Grade: 99%. CAS No. 376641-65-5. Molecular formula: C17H21ClN4O3S2.HCl. Mole weight: 465.42. | |
| BVT 948 | BVT 948. Group: Biochemicals. Grades: Purified. CAS No. 39674-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BVT-948 | BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grade: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24. | |
| BW-180C | BW-180C ([D-Ala2, D-Leu5]-Enkephalin; DADLE) is an δ opioid receptor (DOR) agonist, which belongs to the enkephalin family. Neuroprotective agent. BW-180C reversibly inhibits cellular transcription in neurons without causing cell injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: [D-Ala2, D-Leu5]-Enkephalin; DADLE. CAS No. 63631-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105343. | |
| BW 245C | BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1) agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM and has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation. Synonyms: 7-[(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl]heptanoic acid; 245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C; BW 245C, (R*,S*)-(+-); BW-245C. CAS No. 72814-32-5. Molecular formula: C19H32N2O5. Mole weight: 368.47. | |
| BW 245C | BW 245C is a prostanoid DP-receptor (DP1) agonist, used to study stroke. Uses: Scientific research. Category: Signaling pathways. CAS No. 72814-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101987. | |
| BW 246C | The prostaglandin D2 (PGD2) receptors are the members of G protein-coupled receptors. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). BW 246C is a DP receptor agonist. BW 246C is the less active C-8 diastereomer of the DP receptor agonist BW 245C. The activity of BW 245C is 70-fold greater than that of BW 246C. Synonyms: 8-epi BW 245C. Grade: ≥98%. CAS No. 65705-83-1. Molecular formula: C19H32N2O5. Mole weight: 368.5. | |
| BW 373U86 | BW 373U86 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 1.8, 15 and 34 nM for δ, μ and κ receptors, respectively). Synonyms: BW-373U86; SNC-86; BW 373U86; SNC 86; BW373U86; SNC86; 4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide. Grade: ≥99% by HPLC. CAS No. 155836-50-3. Molecular formula: C27H37N3O2. Mole weight: 435.61. | |
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. | |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. Uses: The treatment of cns disorders as epilepsy, migraine and feeding disorders. Synonyms: BW723C86; BW-723-C-86; BW 723 C 86; BW-723C86; BW 723C86; α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride. Grade: ≥99% by HPLC. CAS No. 160521-72-2. Molecular formula: C16H18N2OS.HCl. Mole weight: 322.85. | |
| BW 723C86 hydrochloride | BW 723C86 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160521-72-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BW 755C | Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grade: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20. | |
| BWA-522 | BWA-522 is an orally active PROTAC degrader targeting full-length androgen receptor (AR-FL) and androgen receptor splice variant 7 (AR-V7). BWA-522 antagonizes the N-terminal domain (AR-NTD) of the androgen receptor, suppresses AR downstream signaling proteins and induces cancer cells apoptosis. BWA-522 inhibits tumor growth in LNCaP xenograft mouse model. BWA-522 can be used for the research of prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3042820-12-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149433. | |
| BW-A78U | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grade: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27. | |
| BW A868C | Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grade: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6. | |
| BW A868C | BW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 118675-50-6. Pack Sizes: 1 mg (21.76 mM * 100 μL in Ethanol). Product ID: HY-50848. | |
| BW-B 70C | BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-α. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grade: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33. | |
| BW-B 70C | BW-B 70C. Group: Biochemicals. Grades: Purified. CAS No. 134470-38-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BWC0977 formic | BWC0977 formic is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 formic exhibits a minimum inhibitory concentration (MIC90) of 0.03-2?μg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3027162-72-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-162959A. | |
| BWX 46 | BWX 46. Group: Biochemicals. Grades: Purified. CAS No. 172997-92-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| BWX 46 Acetate | BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM. Synonyms: ((Cys31,Nva34)-NPY (27-36))2 Acetate. Molecular formula: C118H190N36O30S2. Mole weight: 2657.12. | |
| BX-320 | BX-320 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1; IC50 = 30 nM). BX-320 also induces apoptosis. Synonyms: BX320; N-(3-(4-(3-(3-amino-2,2-dimethyl-3-oxopropanamido)propylamino)-5-bromopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide. CAS No. 702676-93-5. Molecular formula: C23H31BrN8O3. Mole weight: 547.45. | |
| BX341 | BX341, also known as bifluranol, is a new fluorinated bibenzyl anti-androgen and one of a series of bibenzyls designed to present some of the hormonal properties of diethylstilboestrol (DES) but with a lower potential for toxicity. Synonyms: BX341; BX 341; BX-341; 2-fluoro-4-[3-(3-fluoro-4-hydroxyphenyl)pentan-2-yl]phenol; bifluranol; erythro-2,3-bis(3-fluor-4-hydroxyphenyl)pentan. CAS No. 34633-34-6. Molecular formula: C17H18F2O2. Mole weight: 292.32. | |
| BX430 | BX430 is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist with an IC50 of 0.54 μM. BX430 has species specificity. BX430 is used for chronic pain and cardiovascular disease. Uses: Scientific research. Category: Signaling pathways. CAS No. 688309-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110237. | |
| BX 430 | BX 430 is a selective P2X4 allosteric antagonist (IC50 = 0.54 μM) binding noncompetitively to extracellular allosteric site. It exhibits >10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. BX 430 is inactive at mouse and rat P2X4 receptors. Synonyms: BX430; BX-430; BX 430; N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea. Grade: ≥99% by HPLC. CAS No. 688309-70-8. Molecular formula: C15H15Br2N3O. Mole weight: 413.11. | |
| BX471 | BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK-811752. CAS No. 217645-70-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12080. | |
| BX 471 | BX 471 is a selective CCR1 antagonist. Synonyms: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea; BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. | |
| BX 471 | BX 471. Group: Biochemicals. Grades: Purified. CAS No. 217645-70-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX471 hydrochloride | BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Synonyms: BX-471 hydrochloride; BX 471 hydrochloride; (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride. CAS No. 288262-96-4. Molecular formula: C21H25Cl2FN4O3. Mole weight: 471.35. | |
| BX471 hydrochloride | BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with Ki of 1 nM for human CCR1, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZK-811752 hydrochloride. CAS No. 288262-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12080A. | |
| BX 513 | BX 513 is a selective CCR1 receptor antagonist and a full inverse agonist of the HCMV-encoding chemokine receptor US28. It inhibits MIP-1α-induced intracellular calcium mobilization. Synonyms: 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-; 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile; VUF 2274; 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile; BX-513; BX513. Grade: ≥95%. CAS No. 193542-65-3. Molecular formula: C28H29ClN2O. Mole weight: 445.00. | |
| BX 513 hydrochloride | BX 513 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216540-18-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-513 hydrochloride | BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki = 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors, respectively), and also acts as a US28 agonist. It inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Synonyms: BX 513 hydrochloride; 193542-65-3; 1216540-18-9; BX-513 HCl; BX513Hydrochloride; VUF 2274; BX-513; 5-[4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL]-2,2-DIPHENYLPENTANENITRILE HYDROCHLORIDE; 5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile; hydrochloride; BX-513 hydrochloride; 4-(4-CHLOROPHENYL)-4-HYDROXY-A,A-DIPHENYL-1-PIPERIDINEPENTANENITRILE HYDROCHLORIDE; BX 513 HCL; DTXSID30719335; BCP27909; AKOS024457285; AS-57268; VUF 2274; VUF2274; BX513 hydrochloride; BX-513 hydrochloride; 1-Piperidinepentanenitrile,4-(4-chlorophenyl)-4-hydroxy-a,a-diphenyl-,HCl; 5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile--hydrogen chloride (1/1). Grade: ≥99% by HPLC. CAS No. 1216540-18-9. Molecular formula: C28H30Cl2N2O. Mole weight: 481.46. | |
| BX-517 | BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM). Synonyms: (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid; BX-517; BX 517; BX517; PDK1 inhibitor2. CAS No. 850717-64-5. Molecular formula: C15H14N4O2. Mole weight: 282.3. | |
| BX795 | BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 702675-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10514. | |
| BX795 | BX795 Inhibitor. Uses: Scientific use. Product Category: T1830. CAS No. 702675-74-9. |  |
| BX 795 | BX 795. Group: Biochemicals. Grades: Purified. CAS No. 702675-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BX-795 | BX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively. Group: Inhibitors. CAS No. 702675-74-9. Pack Sizes: 10mg. Product ID: S1274. Formula: C23H26IN7O2S. Smiles: C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCCNC(=O)C4=CC=CS4)I. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| BX-795 | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Synonyms: BX 795; BX795. Grade: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47. | |
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