A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
BX 795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. Synonyms: N-(3-(5-Iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide hydrochloride. Grade: 98%. CAS No. 1472611-45-2. Molecular formula: C23H26IN7O2S.HCl. Mole weight: 627.93.
BX912
BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. Synonyms: BX912; BX 912; BX-912. Grade: 0.98. CAS No. 702674-56-4. Molecular formula: C20H23BrN8O. Mole weight: 471.363.
BX-912
BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor (IC50=26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 702674-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11005.
BxPC-3 Transfection Reagent
Transfection Reagent for BxPC3 Pancreatic Cancer Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6321.
Nevada, Texas, USA
Byakangelicin
Byakangelicin. Group: Biochemicals. Grades: Plant Grade. CAS No. 482-25-7. Pack Sizes: 20mg. Molecular Formula: C17H18O7, Molecular Weight: 334.32. US Biological Life Sciences.
Worldwide
Byakangelicin
Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Synonyms: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. Grade: >98%. CAS No. 482-25-7. Molecular formula: C17H18O7. Mole weight: 334.32.
Byakangelicol
Byakangelicol. Group: Biochemicals. CAS No. 26091-79-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
BYK 191023 dihydrochloride
BYK 191023 dihydrochloride is a potent and selective inhibitor of inducible nitric oxide synthase (iNOS) (IC50 = 86, 17000, 162000 nM for iNOS, nNOS and eNOS, respectively) acting in a NADPH- and time-dependent manner. BYK 191023 decreases the nitrite levels in rats, and reverses pathological hypotension in the rodent endotoxin model. Synonyms: BYK191023 Dihydrochloride; BYK-191023 Dihydrochloride; BYK 191023 Dihydrochloride; BYK191023 2HCl; BYK-191023 2HCl; BYK 191023 2HCl; ; 2-[2-(4-Methoxy-2-pyridinyl)ethyl]-1H-imidazo[4,5-b]pyridine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1216722-25-6. Molecular formula: C14H14N4O.2HCl. Mole weight: 327.21.
BYK 191023 Dihydrochloride
BYK 191023 Dihydrochloride was used to study the compositions of pentosan polysulfate salts for oral administration and methods of use. Group: Biochemicals. Grades: Highly Purified. CAS No. 1216722-25-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H14N4O; 2(HCl), Molecular Weight: 254.2923646. US Biological Life Sciences.
Worldwide
BYK204165
BYK204165 is a potent and selective PARP1 inhibitor. BYK204165 inhibits cell-free recombinant human PARP-1 (hPARP-1) with a pIC50 of 7.35 (pKi=7.05), and murine PARP-2 (mPARP-2) with a pIC50 of 5.38, respectively. BYK204165 displays 100-fold selectivity for PARP-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1104546-89-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108632.
BYK 204165
BYK 204165 is a potent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 = 5.38 and 7.35 for PARP-2 and PARP-1, respectively). BYK 204165 is 100-fold more potent for PARP-1 than PARP-2. Synonyms: PARP Inhibitor XIV; BYK204165; BYK-204165; BYK 204165; RT-017290; RT017290; RT 017290. 4-[(1-Methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione. Grade: ≥99% by HPLC. CAS No. 1104546-89-5. Molecular formula: C15H12N2O2. Mole weight: 252.27.
BYK 204165
BYK 204165. Group: Biochemicals. Grades: Purified. CAS No. 1104546-89-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BYK 49187
BYK 49187. Group: Biochemicals. Grades: Purified. CAS No. 163120-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BYK 49187
BYK 49187 is a non-selective PARP inhibitor (pIC50 = 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2, respectively). Synonyms: BYK 49187; BYK49187; BYK-49187; 4,5-Dihydro-2-[4-(4-methyl-1H-imidazol-4-yl)-1-piperidinyl]-6H-imidazo[4,5,1-ij]quinolin-6-one. Grade: ≥98% by HPLC. CAS No. 163120-31-8. Molecular formula: C19H21N5O. Mole weight: 335.4.
Byssochlamic acid
Byssochlamic acid is a mycotoxin produced by Byssochlamys fulva (Paecilomyces variotII) and Bys. nivea. CAS No. 743-51-1. Molecular formula: C18H20O6. Mole weight: 332.35.
Byssochlamysol
Byssochlamysol is a steroid antibiotic extracted from the mycelium of Byssochlamys nivea. It has the activity of inhibiting the growth of tumor cells MCF-7. Molecular formula: C32H50O7. Mole weight: 546.73.
Bz 423
Bz 423 has been found to be an ATP synthase inhibitor and could suppress disease in lupus-prone mice at some extent. Uses: Immunologic factors. Synonyms: Bz-423; Bz 423; Bz423; 7-Chloro-1,3-dihydro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthalenylmethyl)-2H-1,4-benzodiazepin-2-one. Grade: ≥98% by HPLC. CAS No. 216691-95-1. Molecular formula: C27H21ClN2O2. Mole weight: 440.92.
A substrate for cathepsin D. Synonyms: benzoyl-Arg-Gly-Phe-Phe-Leu-MNA; Bz-Arg-Gly-Phe-Phe-Leu-4-methoxy-beta-naphthylamide; Bz-RGFFL-MNA. CAS No. 99112-24-0. Molecular formula: C50H59N9O7. Mole weight: 898.06.
Bz-Arg-His-D-Asp-CH2Cl is a peptide inhibitor of D-Aspartyl Endopeptidase. Synonyms: Bz-RHd-CMK; (Benzoyl-L-arginyl-L-histidyl-D-aspart-1-yl)chloromethane. CAS No. 468102-94-5. Molecular formula: C24H31N8O6Cl. Mole weight: 563.01.
The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5-10 fold greater potency than ATP with EC50 of 0.7 μM. It also exhibits partial agonist activity at P2X1 and P2Y1 receptors. BzATP can also be used as a photoaffinity probe to study adenine nucleotide binding to ATPases. Synonyms: BzATP; Benzoylbenzoic adenosine 5'-triphosphate. Grade: ≥95%. CAS No. 112898-15-4. Molecular formula: C30H39N6O15P3. Mole weight: 816.6.
BzATP triethylammonium salt
Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist. Prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 uM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C24H24N5O15P3. C18H45N3, Molecular Weight: 1018.97. US Biological Life Sciences.
Worldwide
BzBzATP (BzATP)
BzBzATP (BzATP) is a P2X7 receptor agonist exhibits high potency at P2X1 receptor (pEC50 = 8.7). Synonyms: 2'/3'-O-(4-benzoylbenzoyl)adenosine-5'-triphosphate, tri(triethylammonium) salt. Grade: ≥ 95% by HPLC. Molecular formula: C24H24N5O15P3*3(C6H15N) [tri(triethylammonium salt)]; C24H24N5O15P3 (free acid). Mole weight: 1018.97 [tri(triethylammonium salt)]; 715.40 (free acid).
Bz-dA (N6-Benzoyl-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N6-Benzoyl-2'-deoxyadenosine. CAS No. 4546-72-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W011125.
Bz-Gly-Gly-OH
Bz-Gly-Gly-OH. Group: Biochemicals. Alternative Names: Hippuryl glycine; (N-Benzoylglycyl)glycine. Grades: Highly Purified. CAS No. 1145-32-0. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Bz-Gly-Gly-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 1145-32-0. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Bz-Gly-His-Leu hydrate
N-Hippuryl-His-Leu (hydrate) can be used for the identification of ACE inhibitors in vitro. Synonyms: N-Hippuryl-His-Leu hydrate; N-benzoylglycyl-L-histidyl-L-leucine, hydrate; N-Benzoyl-Gly-His-Leu. Grade: 95%. CAS No. 207386-83-2. Molecular formula: C21H27N5O5.xH2O. Mole weight: 447.5 (anhydrous).
BZ-ILE-GLU-GLY-ARG-PNA
Bz-IEGR-pNA is a substrate for plasma kallikrein and coagulation factor XIIa. Synonyms: Nalpha-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide; L-Argininamide, N-benzoyl-L-isoleucyl-L-alpha-glutamylglycyl-N-(4-nitrophenyl)-. CAS No. 59068-47-2. Molecular formula: C32H43N9O9. Mole weight: 697.74.
Bz-Nle-Lys-Arg-Arg-AMC can be used for protease activity assay. In 0.1mL Tris-HCl buffer (50 mM, pH 7.8), Bz-Nle-Lys-Arg-Arg-AMC was hydrolyzed, and the release rate of AMC was observed[1]. Uses: Scientific research. Category: Peptides. CAS No. 863975-32-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2435.
Bz-Nle-Lys-Arg-Arg-AMC
Bz-Nle-Lys-Arg-Arg-AMC is a substrate of dengue virus NS2B-NS3 and yellow fever virus NS3 protease. Synonyms: BZ-NLE-LYS-ARG-ARG-AMC. CAS No. 863975-32-0. Molecular formula: C41H60N12O7. Mole weight: 832.99.
Bz-OMe-rA is a nucleoside analog[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Benzoyl-2-O-methyladenosine. CAS No. 85079-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W141394.
BZ-PHE-VAL-ARG-AMC
BZ-PHE-VAL-ARG-AMC is a sensitive fluorogenic substrate for the quantitative determination of thrombin. Synonyms: N-Benzoyl-Phe-Val-Arg 7-amido-4-methylcoumarin; 4-Methyl-7-(Bz-L-Phe-L-Val-L-Arg-amino)coumarin. CAS No. 88899-22-3. Molecular formula: C37H43N7O6. Mole weight: 681.78.
Bz-RS-iSer(3-Ph)-OMe
Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32981-85-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-W009245.
Bz-Tyr-4-Abz-OH
Bz-Tyr-4-Abz-OH. Group: Biochemicals. Alternative Names: Bentiromide. Grades: Highly Purified. CAS No. 37106-97-1. Pack Sizes: 500mg, 1g. US Biological Life Sciences.
Worldwide
Bz-Val-Gly-Arg-AMC
Bz-VGR-AMC acts as a substrate for the tricorn core protease from Thermoplasma acidophilum. Synonyms: benzoyl-Val-Gly-Arg 4-methyl-7-coumarylamide; benzoyl-Val-Gly-Arg-4-methylcoumaryl-7-amide. CAS No. 87779-49-5. Molecular formula: C30H37N7O6. Mole weight: 591.67.